SIMILAR PATTERNS OF AMINO ACIDS FOR 3K37_A_BCZA468_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cs1 PROTEIN
(CYSTATHIONINE
GAMMA-SYNTHASE)

(Escherichia
coli) 		PF01053
(Cys_Met_Meta_PP) 		3 ASP A  55
ARG A  59
ARG A  49
 None
 0.99A 3k37A-1cs1A:
undetectable		 3k37A-1cs1A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f4h BETA-GALACTOSIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 ASP A 164
ARG A 439
ARG A 210
 None
 1.00A 3k37A-1f4hA:
undetectable		 3k37A-1f4hA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ikp EXOTOXIN A

(Pseudomonas
aeruginosa) 		PF09009
(Exotox-A_cataly)
PF09101
(Exotox-A_bind)
PF09102
(Exotox-A_target) 		3 ASP A 309
ARG A 313
ARG A 458
 None
 0.98A 3k37A-1ikpA:
2.2		 3k37A-1ikpA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iqr PHOTOLYASE

(Thermus
thermophilus) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 ASP A  11
ARG A  13
ARG A 104
 None
None
PO4  A 422 (-2.6A)
 0.90A 3k37A-1iqrA:
undetectable		 3k37A-1iqrA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itu RENAL DIPEPTIDASE

(Homo sapiens) 		PF01244
(Peptidase_M19) 		3 ASP A 235
ARG A 238
ARG A 229
 None
 0.97A 3k37A-1ituA:
undetectable		 3k37A-1ituA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j5s URONATE ISOMERASE

(Thermotoga
maritima) 		PF02614
(UxaC) 		3 ASP A 397
ARG A 407
ARG A 178
 None
 1.00A 3k37A-1j5sA:
undetectable		 3k37A-1j5sA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kej TERMINAL
DEOXYNUCLEOTIDYLTRAN
SFERASE SHORT
ISOFORM

(Mus musculus) 		PF10391
(DNA_pol_lambd_f)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		3 ASP A 343
ARG A 432
ARG A 336
 CO  A 701 (-2.5A)
None
DAD  A 601 (-3.2A)
 0.89A 3k37A-1kejA:
undetectable		 3k37A-1kejA:
19.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1nmb N9 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP N 151
ARG N 152
ARG N 371
 None
 0.93A 3k37A-1nmbN:
53.5		 3k37A-1nmbN:
30.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf6 THREONYL-TRNA
SYNTHETASE

(Escherichia
coli) 		PF00587
(tRNA-synt_2b)
PF02824
(TGS)
PF03129
(HGTP_anticodon)
PF07973
(tRNA_SAD) 		3 ASP A 161
ARG A 145
ARG A 207
 None
 0.86A 3k37A-1qf6A:
undetectable		 3k37A-1qf6A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rpn GDP-MANNOSE
4,6-DEHYDRATASE

(Pseudomonas
aeruginosa) 		PF16363
(GDP_Man_Dehyd) 		3 ASP A 240
ARG A 165
ARG A 295
 None
 0.99A 3k37A-1rpnA:
undetectable		 3k37A-1rpnA:
20.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1v0z NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP A 157
ARG A 158
ARG A 378
 None
 0.34A 3k37A-1v0zA:
53.9		 3k37A-1v0zA:
32.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vcj NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		3 ASP A 149
ARG A 150
ARG A 374
 IBA  A   1 (-3.6A)
IBA  A   1 (-3.9A)
IBA  A   1 (-3.2A)
 0.80A 3k37A-1vcjA:
74.0		 3k37A-1vcjA:
93.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wta 5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE

(Aeropyrum
pernix) 		PF01048
(PNP_UDP_1) 		3 ASP A 152
ARG A 156
ARG A 263
 None
 0.90A 3k37A-1wtaA:
undetectable		 3k37A-1wtaA:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1xog NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP A 152
ARG A 153
ARG A 372
 ABW  A1000 (-3.7A)
ABW  A1000 (-4.1A)
ABW  A1000 (-2.8A)
 0.42A 3k37A-1xogA:
53.4		 3k37A-1xogA:
31.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zef ALKALINE PHOSPHATASE

(Homo sapiens) 		PF00245
(Alk_phosphatase) 		3 ASP A 273
ARG A 314
ARG A 166
 None
None
SEP  A  92 (-2.9A)
 1.01A 3k37A-1zefA:
undetectable		 3k37A-1zefA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zrt UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT

(Rhodobacter
capsulatus) 		PF00355
(Rieske)
PF10399
(UCR_Fe-S_N) 		3 ASP E 161
ARG E 167
ARG E  77
 None
 0.93A 3k37A-1zrtE:
undetectable		 3k37A-1zrtE:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bv5 TYROSINE-PROTEIN
PHOSPHATASE,
NON-RECEPTOR TYPE 5

(Homo sapiens) 		PF00102
(Y_phosphatase) 		3 ASP A 358
ARG A 361
ARG A 300
 None
 1.03A 3k37A-2bv5A:
undetectable		 3k37A-2bv5A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0n A197

(Sulfolobus
turreted
icosahedral
virus 1) 		no annotation 3 ASP A  63
ARG A  14
ARG A  41
 None
 0.99A 3k37A-2c0nA:
undetectable		 3k37A-2c0nA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d6f GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT D

(Methanothermobacter
thermautotrophicus) 		PF00710
(Asparaginase) 		3 ASP A 388
ARG A 367
ARG A 413
 None
 1.01A 3k37A-2d6fA:
undetectable		 3k37A-2d6fA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d7d UVRABC SYSTEM
PROTEIN B

(Bacillus
subtilis) 		PF00271
(Helicase_C)
PF02151
(UVR)
PF04851
(ResIII)
PF12344
(UvrB) 		3 ASP A 373
ARG A 311
ARG A 378
 None
 0.96A 3k37A-2d7dA:
undetectable		 3k37A-2d7dA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2etv IRON(III) ABC
TRANSPORTER,
PERIPLASMIC
IRON-BINDING
PROTEIN, PUTATIVE

(Thermotoga
maritima) 		PF01497
(Peripla_BP_2) 		3 ASP A 321
ARG A 331
ARG A 355
 None
 1.00A 3k37A-2etvA:
undetectable		 3k37A-2etvA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2faq PROBABLE
ATP-DEPENDENT DNA
LIGASE

(Pseudomonas
aeruginosa) 		no annotation 3 ASP A 671
ARG A 752
ARG A 776
 MN  A 501 (-2.5A)
None
ATP  A1304 (-3.0A)
 0.93A 3k37A-2faqA:
undetectable		 3k37A-2faqA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fuq HEPARINASE II
PROTEIN

(Pedobacter
heparinus) 		PF07940
(Hepar_II_III)
PF16332
(DUF4962) 		3 ASP A 644
ARG A 649
ARG A 297
 None
 0.99A 3k37A-2fuqA:
undetectable		 3k37A-2fuqA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwn DIHYDROOROTASE

(Porphyromonas
gingivalis) 		PF01979
(Amidohydro_1) 		3 ASP A 275
ARG A 278
ARG A 299
 None
None
GOL  A 614 (-3.5A)
 1.02A 3k37A-2gwnA:
undetectable		 3k37A-2gwnA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ihm DNA POLYMERASE MU

(Mus musculus) 		PF10391
(DNA_pol_lambd_f)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		3 ASP A 330
ARG A 418
ARG A 323
 NA  A 902 (-2.5A)
None
D3T  A 538 (-2.8A)
 0.99A 3k37A-2ihmA:
undetectable		 3k37A-2ihmA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2is8 MOLYBDOPTERIN
BIOSYNTHESIS ENZYME,
MOAB

(Thermus
thermophilus) 		PF00994
(MoCF_biosynth) 		3 ASP A  11
ARG A  15
ARG A  79
 None
 0.71A 3k37A-2is8A:
undetectable		 3k37A-2is8A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jgr YEGS

(Escherichia
coli) 		PF00781
(DAGK_cat) 		3 ASP A 218
ARG A 299
ARG A 224
 None
 0.94A 3k37A-2jgrA:
undetectable		 3k37A-2jgrA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5v DNA REPLICATION AND
REPAIR PROTEIN RECF

(Deinococcus
radiodurans) 		PF02463
(SMC_N) 		3 ASP A 251
ARG A 190
ARG A 234
 None
 1.00A 3k37A-2o5vA:
undetectable		 3k37A-2o5vA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00106
(adh_short)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 ASP A1534
ARG A1566
ARG A1518
 None
 0.89A 3k37A-2pffA:
undetectable		 3k37A-2pffA:
11.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4j AEROBIC
GLYCEROL-3-PHOSPHATE
DEHYDROGENASE

(Escherichia
coli) 		PF01266
(DAO)
PF16901
(DAO_C) 		3 ASP A 263
ARG A 238
ARG A 395
 None
 0.80A 3k37A-2r4jA:
undetectable		 3k37A-2r4jA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ux8 GLUCOSE-1-PHOSPHATE
URIDYLYLTRANSFERASE

(Sphingomonas
elodea) 		PF00483
(NTP_transferase) 		3 ASP A 134
ARG A 207
ARG A  19
 G1P  A1290 (-3.5A)
None
G1P  A1290 ( 4.9A)
 1.03A 3k37A-2ux8A:
undetectable		 3k37A-2ux8A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wzs PUTATIVE
ALPHA-1,2-MANNOSIDAS
E

(Bacteroides
thetaiotaomicron) 		PF07971
(Glyco_hydro_92) 		3 ASP A 470
ARG A 439
ARG A 351
 None
 1.02A 3k37A-2wzsA:
undetectable		 3k37A-2wzsA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xu0 ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF05424
(Duffy_binding)
PF15447
(NTS) 		3 ASP A 207
ARG A 119
ARG A 134
 None
 0.93A 3k37A-2xu0A:
undetectable		 3k37A-2xu0A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ydy METHIONINE
ADENOSYLTRANSFERASE
2 SUBUNIT BETA

(Homo sapiens) 		PF04321
(RmlD_sub_bind) 		3 ASP A 296
ARG A 148
ARG A 308
 None
 0.89A 3k37A-2ydyA:
undetectable		 3k37A-2ydyA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z3t CYTOCHROME P450

(Streptomyces
sp. TP-A0274) 		PF00067
(p450) 		3 ASP A  54
ARG A  58
ARG A 353
 None
 1.03A 3k37A-2z3tA:
undetectable		 3k37A-2z3tA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zj8 PUTATIVE SKI2-TYPE
HELICASE

(Pyrococcus
furiosus) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF14520
(HHH_5) 		3 ASP A 599
ARG A 602
ARG A 248
 None
 0.76A 3k37A-2zj8A:
undetectable		 3k37A-2zj8A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b54 NUCLEOSIDE
DIPHOSPHATE KINASE

(Saccharomyces
cerevisiae) 		PF00334
(NDK) 		3 ASP A 122
ARG A  89
ARG A 129
 None
PO4  A 154 (-4.2A)
None
 0.98A 3k37A-3b54A:
undetectable		 3k37A-3b54A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cfi TYPE II SECRETORY
PATHWAY, PSEUDOPILIN
EPSJ
NANOBODY NBEPSIJ_11

(Vibrio
vulnificus;
Lama glama) 		PF11612
(T2SSJ)
PF07686
(V-set) 		3 ASP B  83
ARG B 114
ARG C  71
 None
 0.82A 3k37A-3cfiB:
2.0		 3k37A-3cfiB:
17.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ckz NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP A 151
ARG A 152
ARG A 371
 ZMR  A 469 (-3.5A)
ZMR  A 469 (-3.9A)
ZMR  A 469 (-2.9A)
 0.20A 3k37A-3ckzA:
53.8		 3k37A-3ckzA:
35.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d54 FORMYLGLYCINAMIDE
RIBONUCLEOTIDE
AMIDOTRANSFERASE

(Thermotoga
maritima) 		PF02700
(PurS) 		3 ASP B   9
ARG B  80
ARG B  40
 None
 0.97A 3k37A-3d54B:
undetectable		 3k37A-3d54B:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo sapiens) 		PF04042
(DNA_pol_E_B) 		3 ASP A 193
ARG A 443
ARG A   9
 None
 0.96A 3k37A-3e0jA:
undetectable		 3k37A-3e0jA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 GAMMA
CHAIN

(Escherichia
coli) 		PF02665
(Nitrate_red_gam) 		3 ASP C 126
ARG C 112
ARG C  27
 None
HEM  C 806 (-3.9A)
None
 0.84A 3k37A-3egwC:
undetectable		 3k37A-3egwC:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbf PHPD

(Streptomyces
viridochromogenes) 		no annotation 3 ASP A 309
ARG A 312
ARG A 157
 CD  A 505 (-2.1A)
CD  A 505 ( 4.5A)
None
 0.98A 3k37A-3gbfA:
undetectable		 3k37A-3gbfA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gzd SELENOCYSTEINE LYASE

(Homo sapiens) 		PF00266
(Aminotran_5) 		3 ASP C 244
ARG C 242
ARG C 271
 None
 0.90A 3k37A-3gzdC:
undetectable		 3k37A-3gzdC:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3isa PUTATIVE ENOYL-COA
HYDRATASE/ISOMERASE

(Bordetella
parapertussis) 		PF00378
(ECH_1) 		3 ASP A  45
ARG A  49
ARG A  87
 None
 0.69A 3k37A-3isaA:
undetectable		 3k37A-3isaA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3loy COPPER AMINE OXIDASE

(Ogataea angusta) 		PF01179
(Cu_amine_oxid) 		3 ASP A 416
ARG A 430
ARG A 292
 None
 1.04A 3k37A-3loyA:
undetectable		 3k37A-3loyA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qtd PMBA PROTEIN

(Pseudomonas
aeruginosa) 		PF01523
(PmbA_TldD) 		3 ASP A 203
ARG A 232
ARG A 431
 None
 0.93A 3k37A-3qtdA:
undetectable		 3k37A-3qtdA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sql GLYCOSYL HYDROLASE
FAMILY 3

(Synechococcus
sp. PCC 7002) 		PF00933
(Glyco_hydro_3) 		3 ASP A  43
ARG A  35
ARG A  49
 None
None
EDO  A 545 (-4.6A)
 1.03A 3k37A-3sqlA:
undetectable		 3k37A-3sqlA:
19.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ti8 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP A 151
ARG A 152
ARG A 371
 LNV  A 901 (-3.4A)
LNV  A 901 (-4.0A)
LNV  A 901 (-2.9A)
 0.16A 3k37A-3ti8A:
53.9		 3k37A-3ti8A:
35.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tia NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP A 151
ARG A 152
ARG A 371
 LNV  A 801 (-3.4A)
LNV  A 801 (-3.9A)
LNV  A 801 (-2.9A)
 0.20A 3k37A-3tiaA:
55.2		 3k37A-3tiaA:
29.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Corynebacterium
glutamicum) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		3 ASP A 288
ARG A 180
ARG A 325
 None
 0.97A 3k37A-3tx8A:
undetectable		 3k37A-3tx8A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usc HYDROGENASE-1 LARGE
CHAIN

(Escherichia
coli) 		PF00374
(NiFeSe_Hases) 		3 ASP L 211
ARG L 214
ARG L 169
 None
 0.59A 3k37A-3uscL:
undetectable		 3k37A-3uscL:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ayh METAL-BINDING
PROTEIN YODA

(Salmonella
enterica) 		PF09223
(ZinT) 		3 ASP A  52
ARG A  56
ARG A  75
 None
 1.02A 3k37A-4ayhA:
undetectable		 3k37A-4ayhA:
18.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4b7j NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP A 151
ARG A 152
ARG A 368
 G39  A1470 (-3.7A)
G39  A1470 (-3.9A)
G39  A1470 (-3.0A)
 0.24A 3k37A-4b7jA:
53.2		 3k37A-4b7jA:
33.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c2t DNA HELICASE II

(Deinococcus
radiodurans) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		3 ASP A 118
ARG A 145
ARG A 552
 None
 0.91A 3k37A-4c2tA:
undetectable		 3k37A-4c2tA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c30 DNA HELICASE II

(Deinococcus
radiodurans) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		3 ASP A 118
ARG A 145
ARG A 552
 MG  A1664 (-2.9A)
None
None
 0.82A 3k37A-4c30A:
undetectable		 3k37A-4c30A:
19.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4cpn NEURAMINIDASE

(Influenza B
virus) 		PF00064
(Neur) 		3 ASP A 148
ARG A 149
ARG A 373
 ZMR  A 700 (-3.3A)
ZMR  A 700 (-4.0A)
ZMR  A 700 (-3.0A)
 0.19A 3k37A-4cpnA:
75.0		 3k37A-4cpnA:
97.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ddw REVERSE GYRASE

(Thermotoga
maritima) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		3 ASP A 670
ARG A 853
ARG A 693
 None
 1.00A 3k37A-4ddwA:
undetectable		 3k37A-4ddwA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f36 NUCLEOSIDE
DIPHOSPHATE KINASE

(Trypanosoma
brucei) 		PF00334
(NDK) 		3 ASP A 120
ARG A  87
ARG A 127
 None
 1.05A 3k37A-4f36A:
undetectable		 3k37A-4f36A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fnq ALPHA-GALACTOSIDASE
AGAB

(Geobacillus
stearothermophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		3 ASP A 184
ARG A  85
ARG A 161
 None
 0.98A 3k37A-4fnqA:
undetectable		 3k37A-4fnqA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ft6 PROBABLE PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		3 ASP A 122
ARG A 120
ARG A 360
 None
 1.04A 3k37A-4ft6A:
undetectable		 3k37A-4ft6A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4glx DNA LIGASE

(Escherichia
coli) 		PF01653
(DNA_ligase_aden)
PF03119
(DNA_ligase_ZBD)
PF03120
(DNA_ligase_OB)
PF12826
(HHH_2)
PF14520
(HHH_5) 		3 ASP A 138
ARG A 447
ARG A  74
 SO4  A 602 ( 4.9A)
None
SO4  A 602 (-2.5A)
 0.98A 3k37A-4glxA:
undetectable		 3k37A-4glxA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h0m C-PHYCOCYANIN ALPHA
CHAIN

(Synechococcus
elongatus) 		PF00502
(Phycobilisome) 		3 ASP A 148
ARG A 147
ARG A  32
 None
 1.05A 3k37A-4h0mA:
undetectable		 3k37A-4h0mA:
17.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4h53 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP A 151
ARG A 152
ARG A 371
 SLB  A 512 (-3.5A)
SLB  A 512 (-3.8A)
SLB  A 512 (-2.9A)
 0.29A 3k37A-4h53A:
55.1		 3k37A-4h53A:
32.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h8e UNDECAPRENYL
PYROPHOSPHATE
SYNTHASE

(Staphylococcus
aureus) 		PF01255
(Prenyltransf) 		3 ASP A  33
ARG A 201
ARG A  46
 MG  A 301 ( 2.6A)
SO4  A 303 (-3.5A)
FPP  A 302 (-2.8A)
 1.05A 3k37A-4h8eA:
undetectable		 3k37A-4h8eA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hz8 BETA-GLUCOSIDASE

(uncultured
bacterium) 		PF00232
(Glyco_hydro_1) 		3 ASP A  73
ARG A  77
ARG A 121
 None
 0.75A 3k37A-4hz8A:
undetectable		 3k37A-4hz8A:
21.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hzz NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP A 151
ARG A 152
ARG A 371
 G39  A 509 (-3.6A)
G39  A 509 (-3.9A)
G39  A 509 (-2.9A)
 0.23A 3k37A-4hzzA:
52.4		 3k37A-4hzzA:
34.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iws PA0254

(Pseudomonas
aeruginosa) 		PF01977
(UbiD) 		3 ASP A  13
ARG A  17
ARG A 301
 None
 1.02A 3k37A-4iwsA:
undetectable		 3k37A-4iwsA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jn7 ENOLASE

(Agrobacterium
tumefaciens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASP A  15
ARG A 336
ARG A  18
 None
 1.01A 3k37A-4jn7A:
undetectable		 3k37A-4jn7A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k3j HEPATOCYTE GROWTH
FACTOR BETA CHAIN

(Homo sapiens) 		PF01403
(Sema)
PF01437
(PSI) 		3 ASP B 236
ARG B 242
ARG B 217
 None
 0.90A 3k37A-4k3jB:
8.7		 3k37A-4k3jB:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l62 TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF00440
(TetR_N)
PF16925
(TetR_C_13) 		3 ASP A  14
ARG A  18
ARG A  64
 None
 0.76A 3k37A-4l62A:
undetectable		 3k37A-4l62A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9o ISOPRENYL
TRANSFERASE

(Streptococcus
pneumoniae) 		PF01255
(Prenyltransf) 		3 ASP A  28
ARG A 200
ARG A  41
 None
None
SO4  A 302 (-3.7A)
 0.99A 3k37A-4q9oA:
undetectable		 3k37A-4q9oA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qkf ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE ALKB
HOMOLOG 7,
MITOCHONDRIAL

(Homo sapiens) 		PF13532
(2OG-FeII_Oxy_2) 		3 ASP A 111
ARG A  74
ARG A 194
 None
 1.03A 3k37A-4qkfA:
undetectable		 3k37A-4qkfA:
19.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4qn3 NEURAMINIDASE

(Influenza A
virus) 		PF00064
(Neur) 		3 ASP A  69
ARG A  70
ARG A 290
 None
 0.48A 3k37A-4qn3A:
53.7		 3k37A-4qn3A:
32.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rft COAT PROTEIN

(Redspotted
grouper nervous
necrosis virus) 		no annotation 3 ASP A 130
ARG A 176
ARG A 145
 None
 0.99A 3k37A-4rftA:
undetectable		 3k37A-4rftA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v1u LYND

(Lyngbya
aestuarii) 		PF02624
(YcaO) 		3 ASP A 724
ARG A 210
ARG A 323
 None
 0.95A 3k37A-4v1uA:
undetectable		 3k37A-4v1uA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v2d FIBRONECTIN LEUCINE
RICH TRANSMEMBRANE
PROTEIN 2

(Homo sapiens) 		PF01463
(LRRCT)
PF13855
(LRR_8) 		3 ASP A 212
ARG A 239
ARG A 208
 None
 0.98A 3k37A-4v2dA:
undetectable		 3k37A-4v2dA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y1k OUTER MEMBRANE
PROTEIN OPRM

(Pseudomonas
aeruginosa) 		PF02321
(OEP) 		3 ASP A 190
ARG A 194
ARG A 217
 None
 0.81A 3k37A-4y1kA:
undetectable		 3k37A-4y1kA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dih MICROCOMPARTMENTS
PROTEIN

(Haliangium
ochraceum) 		PF00936
(BMC) 		3 ASP A 112
ARG A 202
ARG A 103
 None
 0.99A 3k37A-5dihA:
undetectable		 3k37A-5dihA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5djw ALPHA-GLUCOSIDASE II

(Bacteroides
thetaiotaomicron) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2)
PF17137
(DUF5110) 		3 ASP A 533
ARG A 573
ARG A 159
 None
 0.74A 3k37A-5djwA:
undetectable		 3k37A-5djwA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjj BETA-GLUCOSIDASE

(Aspergillus
oryzae) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 ASP A 762
ARG A 765
ARG A 239
 None
 0.86A 3k37A-5fjjA:
undetectable		 3k37A-5fjjA:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fl7 ATP SYNTHASE SUBUNIT
ALPHA
ATP SYNTHASE SUBUNIT
BETA
ATP SYNTHASE SUBUNIT
GAMMA CHAIN,
MITOCHONDRIAL

(Yarrowia
lipolytica;
Yarrowia
lipolytica;
Yarrowia
lipolytica) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N)
PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF00231
(ATP-synt) 		3 ASP D 347
ARG G  25
ARG A 197
 None
 1.03A 3k37A-5fl7D:
undetectable		 3k37A-5fl7D:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h6j PIERISIN-1

(Pieris rapae) 		no annotation 3 ASP A  72
ARG A  70
ARG A 227
 NAD  A 301 (-3.8A)
NAD  A 301 (-3.4A)
None
 0.90A 3k37A-5h6jA:
undetectable		 3k37A-5h6jA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hrm HALOALKYLPHOSPHORUS
HYDROLASE

(Sphingobium sp.
TCM1) 		no annotation 3 ASP A 289
ARG A 297
ARG A 211
 None
 0.98A 3k37A-5hrmA:
2.4		 3k37A-5hrmA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2g DIOL DEHYDRATASE

(Roseburia
inulinivorans) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 ASP A 745
ARG A 668
ARG A 423
 None
 0.81A 3k37A-5i2gA:
undetectable		 3k37A-5i2gA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ioj HALOALKYLPHOSPHORUS
HYDROLASE

(Sphingobium sp.
TCM1) 		no annotation 3 ASP A 289
ARG A 297
ARG A 211
 None
 1.00A 3k37A-5iojA:
7.9		 3k37A-5iojA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iva LPS-ASSEMBLY PROTEIN
LPTD

(Pseudomonas
aeruginosa) 		PF04453
(OstA_C) 		3 ASP A 373
ARG A 207
ARG A 324
 None
 0.88A 3k37A-5ivaA:
undetectable		 3k37A-5ivaA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lp8 E3 UBIQUITIN-PROTEIN
LIGASE HUWE1

(Homo sapiens) 		no annotation 3 ASP B3995
ARG B3998
ARG B3963
 None
 1.00A 3k37A-5lp8B:
undetectable		 3k37A-5lp8B:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m0o TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE

(Jeotgalicoccus
sp. ATCC 8456) 		PF00067
(p450) 		3 ASP A 239
ARG A  95
ARG A 245
 None
None
EPA  A 502 (-3.8A)
 1.05A 3k37A-5m0oA:
undetectable		 3k37A-5m0oA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg8 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
5
STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
6

(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe) 		no annotation
no annotation 		3 ASP A 438
ARG A 486
ARG B 678
 GOL  A 703 (-3.5A)
None
None
 0.98A 3k37A-5mg8A:
undetectable		 3k37A-5mg8A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE

(Mus musculus) 		no annotation 3 ASP A 140
ARG A 133
ARG A 817
 None
MLY  A 131 ( 4.1A)
None
 0.94A 3k37A-5mhfA:
undetectable		 3k37A-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o34 ENOYL-COA HYDRATASE
CARB HOMOLOGUE

(Streptomyces
cattleya) 		no annotation 3 ASP A 127
ARG A  71
ARG A  82
 None
 1.05A 3k37A-5o34A:
undetectable		 3k37A-5o34A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sva MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 9

(Saccharomyces
cerevisiae) 		PF07544
(Med9) 		3 ASP V 141
ARG V 137
ARG V 149
 None
 0.96A 3k37A-5svaV:
undetectable		 3k37A-5svaV:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tws HUMAN DNA POLYMERASE
MU

(Homo sapiens) 		PF10391
(DNA_pol_lambd_f)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		3 ASP A 330
ARG A 416
ARG A 323
 MG  A 501 (-2.6A)
NA  A 502 ( 4.9A)
GOA  A 503 (-3.0A)
 1.01A 3k37A-5twsA:
undetectable		 3k37A-5twsA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u9c DTDP-4-DEHYDRORHAMNO
SE REDUCTASE

(Yersinia
enterocolitica) 		PF04321
(RmlD_sub_bind) 		3 ASP A  67
ARG A  71
ARG A 186
 None
 0.92A 3k37A-5u9cA:
undetectable		 3k37A-5u9cA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xgu RIBONUCLEASE R

(Escherichia
coli) 		no annotation 3 ASP B 139
ARG B 143
ARG B 356
 None
 0.92A 3k37A-5xguB:
undetectable		 3k37A-5xguB:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6br6 NEURAMINIDASE

(Influenza A
virus) 		no annotation 3 ASP A 151
ARG A 152
ARG A 371
 E3M  A 511 (-2.9A)
E3M  A 511 (-3.8A)
E3M  A 511 (-2.9A)
 0.39A 3k37A-6br6A:
54.6		 3k37A-6br6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bsz METABOTROPIC
GLUTAMATE RECEPTOR 8

(Homo sapiens) 		no annotation 3 ASP A 342
ARG A 346
ARG A 335
 None
 0.60A 3k37A-6bszA:
undetectable		 3k37A-6bszA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6exn PRE-MRNA-SPLICING
FACTOR CLF1

(Saccharomyces
cerevisiae) 		no annotation 3 ASP S 174
ARG S 178
ARG S 207
 None
 0.98A 3k37A-6exnS:
undetectable		 3k37A-6exnS:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g3u -

(-) 		no annotation 3 ASP A  66
ARG A  69
ARG A 717
 None
 0.81A 3k37A-6g3uA:
undetectable		 3k37A-6g3uA:
undetectable