SIMILAR PATTERNS OF AMINO ACIDS FOR 3K13_C_THHC643_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a9n U2A'
SPLICEOSOMAL U2B''

(Homo sapiens;
Homo sapiens) 		PF14580
(LRR_9)
PF00076
(RRM_1) 		3 ASN A  74
ASP A  51
ARG B  28
 None
 0.91A 3k13C-1a9nA:
0.0		 3k13C-1a9nA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b1y PROTEIN
(BETA-AMYLASE)

(Hordeum vulgare) 		PF01373
(Glyco_hydro_14) 		3 ASN A 316
ASP A 321
ARG A 394
 None
 0.83A 3k13C-1b1yA:
7.3		 3k13C-1b1yA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c30 CARBAMOYL PHOSPHATE
SYNTHETASE: LARGE
SUBUNIT

(Escherichia
coli) 		PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 ASN A  50
ASP A  27
ARG A 845
 None
 0.83A 3k13C-1c30A:
0.6		 3k13C-1c30A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezf FARNESYL-DIPHOSPHATE
FARNESYLTRANSFERASE

(Homo sapiens) 		PF00494
(SQS_PSY) 		3 ASN A 205
ASP A 169
ARG A 218
 None
 0.91A 3k13C-1ezfA:
0.0		 3k13C-1ezfA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hle HORSE LEUKOCYTE
ELASTASE INHIBITOR

(Equus caballus) 		PF00079
(Serpin) 		3 ASN A  42
ASP A  45
ARG A 209
 None
 0.82A 3k13C-1hleA:
0.0		 3k13C-1hleA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i84 SMOOTH MUSCLE MYOSIN
HEAVY CHAIN

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF01576
(Myosin_tail_1)
PF02736
(Myosin_N) 		3 ASN S 228
ASP S 465
ARG S 285
 None
 0.82A 3k13C-1i84S:
undetectable		 3k13C-1i84S:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1itk CATALASE-PEROXIDASE

(Haloarcula
marismortui) 		PF00141
(peroxidase) 		3 ASN A 608
ASP A 605
ARG A 116
 None
 0.87A 3k13C-1itkA:
0.0		 3k13C-1itkA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jr7 HYPOTHETICAL 37.4
KDA PROTEIN IN
ILEY-GABD INTERGENIC
REGION

(Escherichia
coli) 		PF08943
(CsiD) 		3 ASN A 286
ASP A 171
ARG A 209
 None
 0.91A 3k13C-1jr7A:
0.5		 3k13C-1jr7A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k32 TRICORN PROTEASE

(Thermoplasma
acidophilum) 		PF03572
(Peptidase_S41)
PF07676
(PD40)
PF14684
(Tricorn_C1)
PF14685
(Tricorn_PDZ) 		3 ASN A 867
ASP A1045
ARG A 132
 None
 0.79A 3k13C-1k32A:
undetectable		 3k13C-1k32A:
14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l5j ACONITATE HYDRATASE
2

(Escherichia
coli) 		PF00330
(Aconitase)
PF06434
(Aconitase_2_N)
PF11791
(Aconitase_B_N) 		3 ASN A 284
ASP A 527
ARG A 159
 None
 0.94A 3k13C-1l5jA:
undetectable		 3k13C-1l5jA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ly1 POLYNUCLEOTIDE
KINASE

(Escherichia
virus T4) 		PF13671
(AAA_33) 		3 ASN A  31
ASP A  36
ARG A 122
 None
 0.93A 3k13C-1ly1A:
undetectable		 3k13C-1ly1A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n71 AAC(6')-II

(Enterococcus
faecium) 		PF00583
(Acetyltransf_1) 		3 ASN A 162
ASP A 168
ARG A  83
 None
None
COA  A 601 (-3.6A)
 0.93A 3k13C-1n71A:
undetectable		 3k13C-1n71A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o7d LYSOSOMAL
ALPHA-MANNOSIDASE
LYSOSOMAL
ALPHA-MANNOSIDASE

(Bos taurus;
Bos taurus) 		PF01074
(Glyco_hydro_38)
PF07748
(Glyco_hydro_38C) 		3 ASN D 748
ASP A 159
ARG A 229
 None
 0.84A 3k13C-1o7dD:
undetectable		 3k13C-1o7dD:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1obf GLYCERALDEHYDE
3-PHOSPHATE
DEHYDROGENASE

(Achromobacter
xylosoxidans) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ASN O  15
ASP O  50
ARG O 199
 None
None
SO4  O 341 (-3.4A)
 0.95A 3k13C-1obfO:
undetectable		 3k13C-1obfO:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ozn RETICULON 4 RECEPTOR

(Homo sapiens) 		PF13855
(LRR_8) 		3 ASN A 164
ASP A 138
ARG A  68
 None
 0.89A 3k13C-1oznA:
undetectable		 3k13C-1oznA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)
PROTEIN (IMPORTIN
ALPHA-2 SUBUNIT)

(Homo sapiens;
Homo sapiens) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ)
PF01749
(IBB) 		3 ASN A 343
ASP A 337
ARG B  29
 None
 0.80A 3k13C-1qgrA:
undetectable		 3k13C-1qgrA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uyo NALP

(Neisseria
meningitidis) 		PF03797
(Autotransporter) 		3 ASN X 940
ASP X 892
ARG X1077
 None
 0.75A 3k13C-1uyoX:
undetectable		 3k13C-1uyoX:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xje RIBONUCLEOTIDE
REDUCTASE,
B12-DEPENDENT

(Thermotoga
maritima) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC) 		3 ASN A 600
ASP A 630
ARG A 514
 None
 0.93A 3k13C-1xjeA:
3.5		 3k13C-1xjeA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xsz GUANINE NUCLEOTIDE
EXCHANGE PROTEIN

(Legionella
pneumophila) 		PF01369
(Sec7) 		3 ASN A 229
ASP A 239
ARG A 348
 None
 0.83A 3k13C-1xszA:
undetectable		 3k13C-1xszA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yoz HYPOTHETICAL PROTEIN
AF0941

(Archaeoglobus
fulgidus) 		PF14591
(AF0941-like) 		3 ASN A  71
ASP A  50
ARG A  89
 None
 0.92A 3k13C-1yozA:
undetectable		 3k13C-1yozA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z05 TRANSCRIPTIONAL
REGULATOR, ROK
FAMILY

(Vibrio cholerae) 		PF00480
(ROK) 		3 ASN A  81
ASP A  25
ARG A 376
 None
 0.90A 3k13C-1z05A:
undetectable		 3k13C-1z05A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z14 VP2

(Rodent
protoparvovirus
1) 		PF00740
(Parvo_coat) 		3 ASN A 235
ASP A 101
ARG A  83
 None
 0.86A 3k13C-1z14A:
undetectable		 3k13C-1z14A:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1z UDP-GLUCOSE
FLAVONOID 3-O
GLYCOSYLTRANSFERASE

(Vitis vinifera) 		PF00201
(UDPGT) 		3 ASN A 145
ASP A 374
ARG A  30
 None
U2F  A1457 (-2.7A)
None
 0.85A 3k13C-2c1zA:
undetectable		 3k13C-2c1zA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dzd PYRUVATE CARBOXYLASE

(Geobacillus
thermodenitrificans) 		PF00289
(Biotin_carb_N)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2) 		3 ASN A 382
ASP A  40
ARG A 296
 None
 0.92A 3k13C-2dzdA:
undetectable		 3k13C-2dzdA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e0i 432AA LONG
HYPOTHETICAL
DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE

(Sulfurisphaera
tokodaii) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 ASN A  20
ASP A 126
ARG A 190
 None
 0.90A 3k13C-2e0iA:
undetectable		 3k13C-2e0iA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f2a GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Staphylococcus
aureus) 		PF01425
(Amidase) 		3 ASN A  81
ASP A 211
ARG A 357
 None
 0.86A 3k13C-2f2aA:
undetectable		 3k13C-2f2aA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgq OUTER MEMBRANE PORIN
PROTEIN 32

(Delftia
acidovorans) 		PF13609
(Porin_4) 		3 ASN X  13
ASP X  64
ARG X 133
 None
CA  X 501 (-3.4A)
MLT  X 700 (-3.1A)
 0.90A 3k13C-2fgqX:
undetectable		 3k13C-2fgqX:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fv0 UNSATURATED
GLUCURONYL HYDROLASE

(Bacillus sp.
GL1) 		PF07470
(Glyco_hydro_88) 		3 ASN A  88
ASP A  41
ARG A 341
 GAD  A 404 (-2.1A)
RAM  A 402 ( 4.6A)
None
 0.87A 3k13C-2fv0A:
undetectable		 3k13C-2fv0A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2go7 HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY

(Streptococcus
pneumoniae) 		PF13419
(HAD_2) 		3 ASN A 181
ASP A   9
ARG A  42
 None
MG  A 207 ( 2.4A)
None
 0.91A 3k13C-2go7A:
undetectable		 3k13C-2go7A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hke DIPHOSPHOMEVALONATE
DECARBOXYLASE,
PUTATIVE

(Trypanosoma
brucei) 		PF00288
(GHMP_kinases_N) 		3 ASN A  13
ASP A 293
ARG A  23
 None
 0.75A 3k13C-2hkeA:
undetectable		 3k13C-2hkeA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i2x METHYLTRANSFERASE 1

(Methanosarcina
barkeri) 		PF12176
(MtaB) 		3 ASN A 273
ASP A 268
ARG A 130
 None
 0.70A 3k13C-2i2xA:
7.9		 3k13C-2i2xA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i3o GAMMA-GLUTAMYLTRANSF
ERASE RELATED
PROTEIN

(Thermoplasma
acidophilum) 		PF01019
(G_glu_transpept) 		3 ASN A 254
ASP A  60
ARG A 226
 None
 0.89A 3k13C-2i3oA:
undetectable		 3k13C-2i3oA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ix8 ELONGATION FACTOR 3A

(Saccharomyces
cerevisiae) 		PF00005
(ABC_tran) 		3 ASN A1571
ASP A1567
ARG A1758
 None
 0.94A 3k13C-2ix8A:
undetectable		 3k13C-2ix8A:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p18 GLYOXALASE II

(Leishmania
infantum) 		PF00753
(Lactamase_B)
PF16123
(HAGH_C) 		3 ASN A 196
ASP A 201
ARG A 184
 None
 0.84A 3k13C-2p18A:
undetectable		 3k13C-2p18A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q5o PHENYLPYRUVATE
DECARBOXYLASE

(Azospirillum
brasilense) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		3 ASN A 364
ASP A 389
ARG A 214
 None
None
PPY  A5003 (-3.3A)
 0.93A 3k13C-2q5oA:
undetectable		 3k13C-2q5oA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr4 PEPTIDASE M3B,
OLIGOENDOPEPTIDASE F

(Enterococcus
faecium) 		PF01432
(Peptidase_M3)
PF08439
(Peptidase_M3_N) 		3 ASN A 494
ASP A 505
ARG A 294
 None
 0.91A 3k13C-2qr4A:
undetectable		 3k13C-2qr4A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vef DIHYDROPTEROATE
SYNTHASE

(Streptococcus
pneumoniae) 		PF00809
(Pterin_bind) 		3 ASN A 110
ASP A 201
ARG A 262
 None
 0.58A 3k13C-2vefA:
18.8		 3k13C-2vefA:
26.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		3 ASN D 551
ASP D 549
ARG D 896
 A  B  -1 ( 3.9A)
A  B  -1 ( 2.3A)
A  B  -6 ( 3.9A)
 0.91A 3k13C-2vnuD:
undetectable		 3k13C-2vnuD:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zah COAT PROTEIN

(Melon necrotic
spot virus) 		PF00729
(Viral_coat) 		3 ASN A 203
ASP A 196
ARG A 175
 None
 0.78A 3k13C-2zahA:
undetectable		 3k13C-2zahA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3auo DNA POLYMERASE BETA
FAMILY (X FAMILY)

(Thermus
thermophilus) 		PF14520
(HHH_5)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb) 		3 ASN A 558
ASP A 340
ARG A 472
 None
 0.91A 3k13C-3auoA:
4.8		 3k13C-3auoA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bil PROBABLE LACI-FAMILY
TRANSCRIPTIONAL
REGULATOR

(Corynebacterium
glutamicum) 		PF13407
(Peripla_BP_4) 		3 ASN A  77
ASP A 276
ARG A 199
 None
 0.88A 3k13C-3bilA:
undetectable		 3k13C-3bilA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cvj PUTATIVE
PHOSPHOHEPTOSE
ISOMERASE

(Bacillus
halodurans) 		PF13580
(SIS_2) 		3 ASN A 169
ASP A 192
ARG A  91
 None
 0.83A 3k13C-3cvjA:
undetectable		 3k13C-3cvjA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnq GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE, TYPE
I

(Burkholderia
pseudomallei) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		3 ASN A  15
ASP A  50
ARG A 199
 None
 0.92A 3k13C-3gnqA:
undetectable		 3k13C-3gnqA:
24.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0l GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Aquifex
aeolicus) 		PF01425
(Amidase) 		3 ASN A  74
ASP A 204
ARG A 350
 None
 0.92A 3k13C-3h0lA:
undetectable		 3k13C-3h0lA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h9j MCCB PROTEIN

(Escherichia
coli) 		PF00899
(ThiF) 		3 ASN A 154
ASP A 148
ARG A 285
 None
APC  A 359 (-3.0A)
None
 0.62A 3k13C-3h9jA:
undetectable		 3k13C-3h9jA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iru PHOSHONOACETALDEHYDE
HYDROLASE LIKE
PROTEIN

(Oleispira
antarctica) 		PF13419
(HAD_2) 		3 ASN A 131
ASP A 191
ARG A  64
 None
 0.95A 3k13C-3iruA:
undetectable		 3k13C-3iruA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ive NUCLEOTIDASE

(Escherichia
coli) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		3 ASN A 396
ASP A 115
ARG A 229
 CTN  A 603 (-3.0A)
CTN  A 603 ( 4.1A)
None
 0.85A 3k13C-3iveA:
undetectable		 3k13C-3iveA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jur EXO-POLY-ALPHA-D-GAL
ACTURONOSIDASE

(Thermotoga
maritima) 		PF00295
(Glyco_hydro_28)
PF12708
(Pectate_lyase_3) 		3 ASN A 331
ASP A 363
ARG A 180
 None
 0.88A 3k13C-3jurA:
undetectable		 3k13C-3jurA:
23.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE

(Bacteroides
thetaiotaomicron) 		PF00809
(Pterin_bind) 		3 ASN A 452
ASP A 519
ARG A 567
 THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.4A)
 0.29A 3k13C-3k13A:
50.1		 3k13C-3k13A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n23 SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1

(Sus scrofa) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF13246
(Cation_ATPase) 		3 ASN A 713
ASP A 710
ARG A 544
 PHD  A 369 ( 3.6A)
MG  A1017 (-3.2A)
None
 0.93A 3k13C-3n23A:
undetectable		 3k13C-3n23A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rqz METALLOPHOSPHOESTERA
SE

(Sphaerobacter
thermophilus) 		PF12850
(Metallophos_2) 		3 ASN A  61
ASP A  63
ARG A 214
 ZN  A 302 (-3.3A)
None
None
 0.92A 3k13C-3rqzA:
undetectable		 3k13C-3rqzA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3stp GALACTONATE
DEHYDRATASE,
PUTATIVE

(Labrenzia
aggregata) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASN A 194
ASP A 186
ARG A  43
 None
 0.95A 3k13C-3stpA:
6.5		 3k13C-3stpA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wjs NADH OXIDASE

(Gluconobacter
oxydans) 		PF00724
(Oxidored_FMN) 		3 ASN A 292
ASP A 230
ARG A  28
 None
HG  A 403 ( 4.8A)
None
 0.81A 3k13C-3wjsA:
9.7		 3k13C-3wjsA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zjx EPSILON-TOXIN

(Clostridium
perfringens) 		PF03318
(ETX_MTX2) 		3 ASN A 136
ASP A 111
ARG A 286
 None
 0.77A 3k13C-3zjxA:
undetectable		 3k13C-3zjxA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zk4 DIPHOSPHONUCLEOTIDE
PHOSPHATASE 1

(Lupinus luteus) 		PF00149
(Metallophos)
PF14008
(Metallophos_C)
PF16656
(Pur_ac_phosph_N) 		3 ASN A 145
ASP A 173
ARG A 199
 None
 0.89A 3k13C-3zk4A:
undetectable		 3k13C-3zk4A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxy SUBTILISIN-LIKE
PROTEIN

(Prochloron
didemni) 		PF00082
(Peptidase_S8) 		3 ASN A 117
ASP A  23
ARG A 213
 None
 0.80A 3k13C-3zxyA:
undetectable		 3k13C-3zxyA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aez WD REPEAT-CONTAINING
PROTEIN SLP1
MITOTIC SPINDLE
CHECKPOINT COMPONENT
MAD3

(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40)
PF08311
(Mad3_BUB1_I) 		3 ASN A 459
ASP A 173
ARG C  55
 None
 0.92A 3k13C-4aezA:
undetectable		 3k13C-4aezA:
22.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ccz METHIONINE SYNTHASE

(Homo sapiens) 		PF00809
(Pterin_bind)
PF02574
(S-methyl_trans) 		3 ASN A 470
ASP A 537
ARG A 585
 THG  A1652 (-3.2A)
THG  A1652 (-3.4A)
THG  A1652 (-3.3A)
 0.81A 3k13C-4cczA:
43.2		 3k13C-4cczA:
30.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ci0 F420-REDUCING
HYDROGENASE, SUBUNIT
ALPHA
F420-REDUCING
HYDROGENASE, SUBUNIT
GAMMA

(Methanothermobacter
marburgensis;
Methanothermobacter
marburgensis) 		PF00374
(NiFeSe_Hases)
PF00037
(Fer4)
PF01058
(Oxidored_q6) 		3 ASN B 245
ASP B 236
ARG A  94
 None
 0.88A 3k13C-4ci0B:
undetectable		 3k13C-4ci0B:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7r PROLINE/BETAINE
TRANSPORTER, RALF

(Legionella
pneumophila;
Rickettsia
prowazekii) 		PF01369
(Sec7) 		3 ASN A 227
ASP A 237
ARG A 346
 None
 0.93A 3k13C-4d7rA:
undetectable		 3k13C-4d7rA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dvg RHO-LIKE SMALL
GTPASE
DIAPHANOUS PROTEIN

(Entamoeba
histolytica;
Entamoeba
histolytica) 		PF00071
(Ras)
PF06367
(Drf_FH3)
PF06371
(Drf_GBD) 		3 ASN A 103
ASP A  28
ARG B 197
 None
 0.95A 3k13C-4dvgA:
2.9		 3k13C-4dvgA:
24.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fbq DNA REPAIR AND
TELOMERE MAINTENANCE
PROTEIN NBS1,DNA
REPAIR PROTEIN RAD32
CHIMERIC PROTEIN

(Schizosaccharomyces
pombe) 		PF00149
(Metallophos)
PF04152
(Mre11_DNA_bind) 		3 ASN A1133
ASP A1135
ARG A1037
 MN  A1501 (-2.5A)
None
None
 0.85A 3k13C-4fbqA:
undetectable		 3k13C-4fbqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gfi MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Agrobacterium
fabrum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASN A 184
ASP A 156
ARG A  51
 None
 0.90A 3k13C-4gfiA:
5.0		 3k13C-4gfiA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h6w N-TERMINAL
CYANOBACTIN PROTEASE

(Planktothrix
agardhii) 		PF00082
(Peptidase_S8) 		3 ASN A 120
ASP A  26
ARG A 216
 None
 0.73A 3k13C-4h6wA:
undetectable		 3k13C-4h6wA:
25.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc8 HOPS COMPONENT VPS33

(Chaetomium
thermophilum) 		PF00995
(Sec1) 		3 ASN A 264
ASP A  38
ARG A 238
 None
 0.95A 3k13C-4jc8A:
undetectable		 3k13C-4jc8A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc8 HOPS COMPONENT VPS33

(Chaetomium
thermophilum) 		PF00995
(Sec1) 		3 ASN A 264
ASP A  38
ARG A 421
 None
 0.87A 3k13C-4jc8A:
undetectable		 3k13C-4jc8A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4krg PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
1

(Haemonchus
contortus) 		PF08241
(Methyltransf_11) 		3 ASN A 122
ASP A  39
ARG A 163
 SAH  A 502 (-3.9A)
None
None
 0.91A 3k13C-4krgA:
undetectable		 3k13C-4krgA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lsb LYASE/MUTASE

(Burkholderia
cenocepacia) 		PF13714
(PEP_mutase) 		3 ASN A  28
ASP A  87
ARG A 165
 None
MG  A 501 ( 4.1A)
None
 0.95A 3k13C-4lsbA:
9.2		 3k13C-4lsbA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mh1 SORBOSE
DEHYDROGENASE

(Ketogulonicigenium
vulgare) 		PF13360
(PQQ_2) 		3 ASN A 531
ASP A 479
ARG A 108
 None
 0.91A 3k13C-4mh1A:
undetectable		 3k13C-4mh1A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nw4 LIPOPROTEIN S-LAYER
PROTEIN

(Enterococcus
faecalis) 		PF16103
(DUF4822) 		3 ASN A 297
ASP A 217
ARG A 249
 None
None
SO4  A 405 (-3.7A)
 0.84A 3k13C-4nw4A:
undetectable		 3k13C-4nw4A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r6y PUTATIVE
2-AMINOETHYLPHOSPHON
ATE-BINDING
PERIPLASMIC PROTEIN

(Salmonella
enterica) 		PF13343
(SBP_bac_6) 		3 ASN A 122
ASP A 162
ARG A 226
 GOL  A 401 (-4.1A)
ACT  A 402 (-3.4A)
None
 0.93A 3k13C-4r6yA:
undetectable		 3k13C-4r6yA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rhh BETA-XYLOSIDASE

(Geobacillus
stearothermophilus) 		PF03512
(Glyco_hydro_52) 		3 ASN A 566
ASP A 498
ARG A 611
 None
 0.93A 3k13C-4rhhA:
undetectable		 3k13C-4rhhA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ry8 PERIPLASMIC BINDING
PROTEIN

(Pseudothermotoga
lettingae) 		PF13407
(Peripla_BP_4) 		3 ASN A 162
ASP A 170
ARG A  41
 None
 0.87A 3k13C-4ry8A:
undetectable		 3k13C-4ry8A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xdt FAD:PROTEIN FMN
TRANSFERASE

(Treponema
pallidum) 		PF02424
(ApbE) 		3 ASN A 109
ASP A 159
ARG A 217
 FAD  A 401 ( 4.9A)
FAD  A 401 (-2.3A)
None
 0.81A 3k13C-4xdtA:
undetectable		 3k13C-4xdtA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zck GTP-BINDING PROTEIN
TYPA/BIPA

(Escherichia
coli) 		PF00679
(EFG_C) 		3 ASN A 601
ASP A 575
ARG A 507
 None
 0.63A 3k13C-4zckA:
undetectable		 3k13C-4zckA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aw4 NA, K-ATPASE ALPHA
SUBUNIT

(Squalus
acanthias) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF13246
(Cation_ATPase) 		3 ASN A 720
ASP A 376
ARG A 551
 MF4  A2001 (-3.4A)
MF4  A2001 ( 2.4A)
None
 0.94A 3k13C-5aw4A:
undetectable		 3k13C-5aw4A:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3h PROTEIN SHORT-ROOT

(Arabidopsis
thaliana) 		PF03514
(GRAS) 		3 ASN B 139
ASP B 144
ARG B 431
 None
 0.87A 3k13C-5b3hB:
undetectable		 3k13C-5b3hB:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4c UDP-2,3-DIACYLGLUCOS
AMINE HYDROLASE

(Pseudomonas
aeruginosa) 		PF00149
(Metallophos) 		3 ASN A  10
ASP A  81
ARG A 213
 None
 0.72A 3k13C-5b4cA:
undetectable		 3k13C-5b4cA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bv9 CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Bacillus
pumilus) 		PF02011
(Glyco_hydro_48) 		3 ASN A 410
ASP A 399
ARG A 631
 GOL  A 818 (-3.1A)
ACT  A 813 (-3.2A)
None
 0.72A 3k13C-5bv9A:
undetectable		 3k13C-5bv9A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dot CARBAMOYL-PHOSPHATE
SYNTHASE [AMMONIA],
MITOCHONDRIAL

(Homo sapiens) 		PF00117
(GATase)
PF00988
(CPSase_sm_chain)
PF02142
(MGS)
PF02786
(CPSase_L_D2)
PF02787
(CPSase_L_D3) 		3 ASN A1016
ASP A 993
ARG A 718
 None
 0.92A 3k13C-5dotA:
undetectable		 3k13C-5dotA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqn CYTOCHROME P450
CYP125

(Mycolicibacterium
smegmatis) 		PF00067
(p450) 		3 ASN A  18
ASP A  11
ARG A 301
 None
None
HEM  A 501 (-3.0A)
 0.88A 3k13C-5dqnA:
undetectable		 3k13C-5dqnA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ffj ENDONUCLEASE AND
METHYLASE LLAGI

(Lactococcus
lactis) 		PF00271
(Helicase_C)
PF02384
(N6_Mtase)
PF04851
(ResIII) 		3 ASN A1086
ASP A1117
ARG A1375
 None
 0.94A 3k13C-5ffjA:
undetectable		 3k13C-5ffjA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fhi GLUTATHIONE
S-TRANSFERASE,
PUTATIVE

(Aspergillus
fumigatus) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 ASN A 180
ASP A 136
ARG A 121
 None
 0.83A 3k13C-5fhiA:
undetectable		 3k13C-5fhiA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz SPINDLE POLE BODY
COMPONENT SPC97
TUBULIN GAMMA CHAIN

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF04130
(Spc97_Spc98)
PF00091
(Tubulin)
PF03953
(Tubulin_C) 		3 ASN C 240
ASP C  47
ARG A 664
 None
 0.86A 3k13C-5flzC:
undetectable		 3k13C-5flzC:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gqf LACTO-N-BIOSIDASE

(Bifidobacterium
longum) 		no annotation 3 ASN A 402
ASP A 341
ARG A 204
 None
NAG  A 704 ( 4.2A)
None
 0.91A 3k13C-5gqfA:
undetectable		 3k13C-5gqfA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5it1 PUTATIVE CYTOCHROME
P450

(Streptomyces
peucetius) 		PF00067
(p450) 		3 ASN A 144
ASP A 137
ARG A  15
 None
 0.81A 3k13C-5it1A:
undetectable		 3k13C-5it1A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjo UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF08238
(Sel1) 		3 ASN A 151
ASP A 121
ARG A  48
 None
 0.88A 3k13C-5jjoA:
undetectable		 3k13C-5jjoA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jkp UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF08238
(Sel1) 		3 ASN A 151
ASP A 121
ARG A  48
 None
 0.90A 3k13C-5jkpA:
undetectable		 3k13C-5jkpA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jnm MANNITOL-1-PHOSPHATE
5-DEHYDROGENASE

(Staphylococcus
aureus) 		no annotation 3 ASN A 271
ASP A  52
ARG A  13
 None
 0.90A 3k13C-5jnmA:
undetectable		 3k13C-5jnmA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l9p PERIPLASMIC BINDING
PROTEIN

(Agrobacterium
tumefaciens) 		PF13416
(SBP_bac_8) 		3 ASN A  68
ASP A  92
ARG A 351
 None
 0.90A 3k13C-5l9pA:
undetectable		 3k13C-5l9pA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE

(Mus musculus) 		no annotation 3 ASN A 508
ASP A 448
ARG A 748
 None
6A9  A 903 (-3.0A)
None
 0.77A 3k13C-5mhfA:
undetectable		 3k13C-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mms CYSTATHIONINE
BETA-SYNTHASE

(Homo sapiens) 		PF00291
(PALP) 		3 ASN A 294
ASP A 281
ARG A  45
 None
 0.95A 3k13C-5mmsA:
undetectable		 3k13C-5mmsA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ocd -

(-) 		no annotation 3 ASN A  98
ASP A  42
ARG A 154
 None
 0.93A 3k13C-5ocdA:
undetectable		 3k13C-5ocdA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5svc ACETONE CARBOXYLASE
ALPHA SUBUNIT

(Xanthobacter
autotrophicus) 		PF02538
(Hydantoinase_B) 		3 ASN A 539
ASP A 545
ARG A 651
 None
 0.90A 3k13C-5svcA:
undetectable		 3k13C-5svcA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tum TETRACYCLINE
DESTRUCTASE TET(56)

(Legionella
longbeachae) 		PF01494
(FAD_binding_3) 		3 ASN A 209
ASP A 211
ARG A  49
 None
 0.91A 3k13C-5tumA:
undetectable		 3k13C-5tumA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u1d ANTIGEN PEPTIDE
TRANSPORTER 2
TAP TRANSPORTER
INHIBITOR ICP47

(Homo sapiens;
Human
alphaherpesvirus
1) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane)
PF05363
(Herpes_US12) 		3 ASN B 267
ASP B 432
ARG X  37
 None
 0.76A 3k13C-5u1dB:
undetectable		 3k13C-5u1dB:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5udb DNA REPLICATION
LICENSING FACTOR
MCM2

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		3 ASN 2 384
ASP 2 413
ARG 2 288
 None
 0.78A 3k13C-5udb2:
undetectable		 3k13C-5udb2:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5win -

(-) 		no annotation 3 ASN A 612
ASP A 699
ARG A 588
 None
 0.94A 3k13C-5winA:
undetectable		 3k13C-5winA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c0f RIBOSOME PRODUCTION
FACTOR 1

(Saccharomyces
cerevisiae) 		no annotation 3 ASN I 234
ASP I 237
ARG I 272
 None
 0.74A 3k13C-6c0fI:
undetectable		 3k13C-6c0fI:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6q EXOSOME RNA HELICASE
MTR4

(Homo sapiens) 		no annotation 3 ASN M 219
ASP M 208
ARG M 244
 None
 0.87A 3k13C-6d6qM:
undetectable		 3k13C-6d6qM:
undetectable