SIMILAR PATTERNS OF AMINO ACIDS FOR 3K13_A_THHA642_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ad1 DIHYDROPTEROATE
SYNTHETASE

(Staphylococcus
aureus) 		PF00809
(Pterin_bind) 		3 ASN A 246
ASP A 220
ARG A  52
 None
 0.77A 3k13A-1ad1A:
19.1		 3k13A-1ad1A:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1al8 GLYCOLATE OXIDASE

(Spinacia
oleracea) 		PF01070
(FMN_dh) 		3 ASN A  38
ASP A 285
ARG A 209
 None
FMN  A 360 (-2.7A)
None
 0.82A 3k13A-1al8A:
7.3		 3k13A-1al8A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b1y PROTEIN
(BETA-AMYLASE)

(Hordeum vulgare) 		PF01373
(Glyco_hydro_14) 		3 ASN A 316
ASP A 321
ARG A 394
 None
 0.90A 3k13A-1b1yA:
6.8		 3k13A-1b1yA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bev BOVINE ENTEROVIRUS
COAT PROTEINS VP1 TO
VP4
BOVINE ENTEROVIRUS
COAT PROTEINS VP1 TO
VP4

(Enterovirus E;
Enterovirus E) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 ASN 2 203
ASP 2 196
ARG 1 100
 None
None
MYR  1 900 (-4.7A)
 0.84A 3k13A-1bev2:
undetectable		 3k13A-1bev2:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e0t PYRUVATE KINASE

(Escherichia
coli) 		PF00224
(PK)
PF02887
(PK_C) 		3 ASN A 159
ASP A 127
ARG A  32
 None
 0.89A 3k13A-1e0tA:
7.6		 3k13A-1e0tA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f6y 5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE

(Moorella
thermoacetica) 		PF00809
(Pterin_bind) 		3 ASN A  96
ASP A 160
ARG A 207
 None
 0.51A 3k13A-1f6yA:
29.0		 3k13A-1f6yA:
26.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l0q SURFACE LAYER
PROTEIN

(Methanosarcina
mazei) 		PF00801
(PKD)
PF10282
(Lactonase) 		3 ASN A 224
ASP A 245
ARG A 158
 None
 0.76A 3k13A-1l0qA:
undetectable		 3k13A-1l0qA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n71 AAC(6')-II

(Enterococcus
faecium) 		PF00583
(Acetyltransf_1) 		3 ASN A 162
ASP A 168
ARG A  83
 None
None
COA  A 601 (-3.6A)
 0.88A 3k13A-1n71A:
undetectable		 3k13A-1n71A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1no7 MAJOR CAPSID PROTEIN

(Human
alphaherpesvirus
1) 		PF03122
(Herpes_MCP) 		3 ASN A 997
ASP A 548
ARG A 595
 None
 0.93A 3k13A-1no7A:
undetectable		 3k13A-1no7A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vzv VARICELLA-ZOSTER
VIRUS PROTEASE

(Human
alphaherpesvirus
3) 		PF00716
(Peptidase_S21) 		3 ASN A 154
ASP A 156
ARG A  98
 None
 0.77A 3k13A-1vzvA:
undetectable		 3k13A-1vzvA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wue MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME
FAMILY PROTEIN

(Enterococcus
faecalis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASN A1191
ASP A1239
ARG A1299
 None
 0.93A 3k13A-1wueA:
5.8		 3k13A-1wueA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE

(Sulfurisphaera
tokodaii) 		PF00294
(PfkB) 		3 ASN A 286
ASP A 250
ARG A 108
 None
 0.93A 3k13A-1wyeA:
2.6		 3k13A-1wyeA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xwi SKD1 PROTEIN

(Homo sapiens) 		PF00004
(AAA)
PF09336
(Vps4_C) 		3 ASN A 279
ASP A 234
ARG A 346
 SO4  A 601 ( 3.5A)
SO4  A 601 ( 4.4A)
None
 0.88A 3k13A-1xwiA:
undetectable		 3k13A-1xwiA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yoz HYPOTHETICAL PROTEIN
AF0941

(Archaeoglobus
fulgidus) 		PF14591
(AF0941-like) 		3 ASN A  71
ASP A  50
ARG A  26
 None
 0.76A 3k13A-1yozA:
undetectable		 3k13A-1yozA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z63 HELICASE OF THE
SNF2/RAD54 FAMILY

(Sulfolobus
solfataricus) 		PF00176
(SNF2_N)
PF00271
(Helicase_C) 		3 ASN A 566
ASP A 562
ARG A 821
 None
 0.92A 3k13A-1z63A:
undetectable		 3k13A-1z63A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zk7 MERCURIC REDUCTASE

(Pseudomonas
aeruginosa) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		3 ASN A 330
ASP A 335
ARG A 426
 None
 0.84A 3k13A-1zk7A:
undetectable		 3k13A-1zk7A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gfi PHYTASE

(Debaryomyces
castellii) 		PF00328
(His_Phos_2) 		3 ASN A 220
ASP A 293
ARG A 170
 None
 0.88A 3k13A-2gfiA:
undetectable		 3k13A-2gfiA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hwk HELICASE NSP2

(Venezuelan
equine
encephalitis
virus) 		PF01707
(Peptidase_C9) 		3 ASN A 517
ASP A 529
ARG A 738
 None
 0.92A 3k13A-2hwkA:
undetectable		 3k13A-2hwkA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i5g AMIDOHYDROLASE

(Pseudomonas
aeruginosa) 		PF01244
(Peptidase_M19) 		3 ASN A 281
ASP A 250
ARG A 272
 None
 0.77A 3k13A-2i5gA:
7.3		 3k13A-2i5gA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j4l URIDYLATE KINASE

(Sulfolobus
solfataricus) 		PF00696
(AA_kinase) 		3 ASN A  75
ASP A  13
ARG A  55
 None
 0.86A 3k13A-2j4lA:
undetectable		 3k13A-2j4lA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7n RNA-DEPENDENT RNA
POLYMERASE

(Neurospora
crassa) 		PF05183
(RdRP) 		3 ASN A1080
ASP A 587
ARG A 962
 None
 0.89A 3k13A-2j7nA:
undetectable		 3k13A-2j7nA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mbr URIDINE
DIPHOSPHO-N-ACETYLEN
OLPYRUVYLGLUCOSAMINE
REDUCTASE

(Escherichia
coli) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		3 ASN A 226
ASP A 220
ARG A  66
 FAD  A 401 (-3.5A)
None
None
 0.83A 3k13A-2mbrA:
undetectable		 3k13A-2mbrA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1o PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE

(Cryptosporidium
parvum) 		PF00348
(polyprenyl_synt) 		3 ASN A 262
ASP A 268
ARG A  75
 None
MG  A 501 ( 4.8A)
None
 0.71A 3k13A-2o1oA:
undetectable		 3k13A-2o1oA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3e DIAMINOPIMELATE
DECARBOXYLASE

(Aquifex
aeolicus) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		3 ASN A 314
ASP A 352
ARG A 365
 None
 0.85A 3k13A-2p3eA:
7.6		 3k13A-2p3eA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfa BOREALIN
INNER CENTROMERE
PROTEIN

(Homo sapiens;
Homo sapiens) 		PF10444
(Nbl1_Borealin_N)
PF12178
(INCENP_N) 		3 ASN C  25
ASP B  42
ARG B  30
 None
 0.70A 3k13A-2qfaC:
undetectable		 3k13A-2qfaC:
12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qm6 GAMMA-GLUTAMYLTRANSP
EPTIDASE

(Helicobacter
pylori) 		PF01019
(G_glu_transpept) 		3 ASN B 418
ASP B 422
ARG B 513
 None
GLU  B   1 (-2.9A)
None
 0.84A 3k13A-2qm6B:
undetectable		 3k13A-2qm6B:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wok CLAVULANIC ACID
BIOSYNTHESIS
OLIGOPEPTIDE BINDING
PROTEIN 2

(Streptomyces
clavuligerus) 		PF00496
(SBP_bac_5) 		3 ASN A 272
ASP A 261
ARG A 338
 None
 0.83A 3k13A-2wokA:
undetectable		 3k13A-2wokA:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE

(Staphylococcus
aureus) 		PF00155
(Aminotran_1_2) 		3 ASN A 156
ASP A 129
ARG A 277
 None
None
PLP  A1429 (-2.9A)
 0.86A 3k13A-2x5fA:
undetectable		 3k13A-2x5fA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x60 MANNOSE-1-PHOSPHATE
GUANYLYLTRANSFERASE

(Thermotoga
maritima) 		PF00483
(NTP_transferase) 		3 ASN A  85
ASP A 239
ARG A  43
 MG  A 602 (-4.4A)
None
None
 0.69A 3k13A-2x60A:
undetectable		 3k13A-2x60A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ycj 5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE

(Carboxydothermus
hydrogenoformans) 		PF00809
(Pterin_bind) 		3 ASN A  97
ASP A 161
ARG A 208
 C2F  A3000 (-3.0A)
C2F  A3000 (-3.5A)
C2F  A3000 ( 2.6A)
 0.43A 3k13A-2ycjA:
29.6		 3k13A-2ycjA:
29.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dy5 ALLENE OXIDE
SYNTHASE-LIPOXYGENAS
E PROTEIN

(Plexaura
homomalla) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 ASN A 611
ASP A 862
ARG A 641
 None
 0.85A 3k13A-3dy5A:
undetectable		 3k13A-3dy5A:
14.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 ALPHA
CHAIN

(Escherichia
coli) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF14710
(Nitr_red_alph_N) 		3 ASN A 545
ASP A 551
ARG A1036
 None
 0.69A 3k13A-3egwA:
undetectable		 3k13A-3egwA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3faw RETICULOCYTE BINDING
PROTEIN

(Streptococcus
agalactiae) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 ASN A 920
ASP A1007
ARG A 771
 CL  A1226 (-4.0A)
None
None
 0.91A 3k13A-3fawA:
4.5		 3k13A-3fawA:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g25 GLYCEROL KINASE

(Staphylococcus
aureus) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		3 ASN A 184
ASP A 244
ARG A 105
 None
GOL  A 499 ( 2.8A)
None
 0.84A 3k13A-3g25A:
undetectable		 3k13A-3g25A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Schizosaccharomyces
pombe) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 ASN B 206
ASP B 615
ARG B 408
 None
 0.79A 3k13A-3h0gB:
undetectable		 3k13A-3h0gB:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i0z PUTATIVE
TAGATOSE-6-PHOSPHATE
KETOSE/ALDOSE
ISOMERASE

(Streptococcus
pneumoniae) 		PF01380
(SIS) 		3 ASN A 120
ASP A 148
ARG A  19
 None
 0.81A 3k13A-3i0zA:
undetectable		 3k13A-3i0zA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ive NUCLEOTIDASE

(Escherichia
coli) 		PF00149
(Metallophos)
PF02872
(5_nucleotid_C) 		3 ASN A 396
ASP A 115
ARG A 229
 CTN  A 603 (-3.0A)
CTN  A 603 ( 4.1A)
None
 0.60A 3k13A-3iveA:
undetectable		 3k13A-3iveA:
21.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE

(Bacteroides
thetaiotaomicron) 		PF00809
(Pterin_bind) 		3 ASN A 452
ASP A 519
ARG A 573
 THH  A 642 (-3.0A)
THH  A 642 (-3.4A)
THH  A 642 (-3.1A)
 0.06A 3k13A-3k13A:
51.9		 3k13A-3k13A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3now UNC-45 PROTEIN,
SD10334P

(Drosophila
melanogaster) 		PF11701
(UNC45-central) 		3 ASN A 571
ASP A 531
ARG A 403
 None
 0.90A 3k13A-3nowA:
undetectable		 3k13A-3nowA:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pjx CYCLIC DIMERIC GMP
BINDING PROTEIN

(Pseudomonas
fluorescens) 		PF00563
(EAL)
PF00990
(GGDEF) 		3 ASN A 281
ASP A 290
ARG A 247
 None
 0.81A 3k13A-3pjxA:
4.1		 3k13A-3pjxA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3prl NADP-DEPENDENT
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Bacillus
halodurans) 		PF00171
(Aldedh) 		3 ASN A 366
ASP A 336
ARG A 381
 None
 0.91A 3k13A-3prlA:
undetectable		 3k13A-3prlA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r9r PHOSPHORIBOSYLAMINOI
MIDAZOLE-SUCCINOCARB
OXAMIDE SYNTHASE

(Mycobacteroides
abscessus) 		PF01259
(SAICAR_synt) 		3 ASN A 154
ASP A 152
ARG A 244
 ASN  A 154 ( 0.6A)
ASP  A 152 ( 0.6A)
ARG  A 244 ( 0.6A)
 0.83A 3k13A-3r9rA:
undetectable		 3k13A-3r9rA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3stp GALACTONATE
DEHYDRATASE,
PUTATIVE

(Labrenzia
aggregata) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 ASN A 194
ASP A 186
ARG A  43
 None
 0.72A 3k13A-3stpA:
9.6		 3k13A-3stpA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t05 PYRUVATE KINASE

(Staphylococcus
aureus) 		PF00224
(PK)
PF00391
(PEP-utilizers)
PF02887
(PK_C) 		3 ASN A 446
ASP A 474
ARG A 424
 None
 0.85A 3k13A-3t05A:
9.4		 3k13A-3t05A:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t20 CIS-ACONITATE PORIN
OPDH

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		3 ASN A 250
ASP A 227
ARG A 365
 None
 0.88A 3k13A-3t20A:
undetectable		 3k13A-3t20A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ubo ADENOSINE KINASE

(Sinorhizobium
meliloti) 		PF00294
(PfkB) 		3 ASN A  63
ASP A  15
ARG A 195
 ADN  A 353 (-3.4A)
ADN  A 353 (-2.8A)
None
 0.82A 3k13A-3uboA:
undetectable		 3k13A-3uboA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ujz METALLOPROTEASE STCE

(Escherichia
coli) 		PF10462
(Peptidase_M66) 		3 ASN A 251
ASP A 134
ARG A 324
 None
 0.87A 3k13A-3ujzA:
undetectable		 3k13A-3ujzA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ar9 COLLAGENASE COLT

(Clostridium
tetani) 		PF01752
(Peptidase_M9) 		3 ASN A 660
ASP A 360
ARG A 464
 None
 0.87A 3k13A-4ar9A:
undetectable		 3k13A-4ar9A:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bju N-ACETYLGLUCOSAMINE-
PHOSPHATE MUTASE

(Aspergillus
fumigatus) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I) 		3 ASN A  71
ASP A 260
ARG A 505
 None
 0.92A 3k13A-4bjuA:
undetectable		 3k13A-4bjuA:
21.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ccz METHIONINE SYNTHASE

(Homo sapiens) 		PF00809
(Pterin_bind)
PF02574
(S-methyl_trans) 		3 ASN A 470
ASP A 537
ARG A 585
 THG  A1652 (-3.2A)
THG  A1652 (-3.4A)
THG  A1652 (-3.3A)
 0.64A 3k13A-4cczA:
43.4		 3k13A-4cczA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ccz METHIONINE SYNTHASE

(Homo sapiens) 		PF00809
(Pterin_bind)
PF02574
(S-methyl_trans) 		3 ASN A 470
ASP A 537
ARG A 591
 THG  A1652 (-3.2A)
THG  A1652 (-3.4A)
THG  A1652 (-3.0A)
 0.19A 3k13A-4cczA:
43.4		 3k13A-4cczA:
30.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e3a SUGAR KINASE PROTEIN

(Rhizobium etli) 		PF00294
(PfkB) 		3 ASN A  61
ASP A  13
ARG A 193
 ADN  A 500 (-3.5A)
ADN  A 500 (-2.7A)
None
 0.89A 3k13A-4e3aA:
2.4		 3k13A-4e3aA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ee9 ENDOGLUCANASE

(uncultured
bacterium) 		PF00150
(Cellulase) 		3 ASN A   8
ASP A 131
ARG A 176
 None
 0.85A 3k13A-4ee9A:
10.4		 3k13A-4ee9A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fdj N-ACETYLGALACTOSAMIN
E-6-SULFATASE

(Homo sapiens) 		PF00884
(Sulfatase)
PF14707
(Sulfatase_C) 		3 ASN A 289
ASP A  39
ARG A 175
 CA  A 603 (-2.9A)
CA  A 603 (-3.5A)
None
 0.89A 3k13A-4fdjA:
undetectable		 3k13A-4fdjA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h54 DIGUANYLATE CYCLASE
YDEH

(Escherichia
coli) 		PF00990
(GGDEF) 		3 ASN A 173
ASP A 182
ARG A 140
 GAV  A 402 (-3.1A)
GAV  A 402 (-3.5A)
None
 0.78A 3k13A-4h54A:
undetectable		 3k13A-4h54A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kh8 HYPOTHETICAL PROTEIN

(Enterococcus
faecalis) 		PF16103
(DUF4822) 		3 ASN A 323
ASP A 243
ARG A 275
 None
None
SO4  A 407 ( 4.2A)
 0.81A 3k13A-4kh8A:
undetectable		 3k13A-4kh8A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lx4 ENDOGLUCANASE(ENDO-1
,4-BETA-GLUCANASE)PR
OTEIN

(Pseudomonas
stutzeri) 		PF00150
(Cellulase) 		3 ASN A  17
ASP A  97
ARG A 178
 None
 0.89A 3k13A-4lx4A:
8.1		 3k13A-4lx4A:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4myc IRON-SULFUR CLUSTERS
TRANSPORTER ATM1,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00005
(ABC_tran)
PF00664
(ABC_membrane) 		3 ASN A 421
ASP A 506
ARG A 413
 None
 0.80A 3k13A-4mycA:
undetectable		 3k13A-4mycA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nw4 LIPOPROTEIN S-LAYER
PROTEIN

(Enterococcus
faecalis) 		PF16103
(DUF4822) 		3 ASN A 297
ASP A 217
ARG A 249
 None
None
SO4  A 405 (-3.7A)
 0.75A 3k13A-4nw4A:
undetectable		 3k13A-4nw4A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o1e DIHYDROPTEROATE
SYNTHASE DHPS

(Desulfitobacterium
hafniense) 		PF00809
(Pterin_bind) 		3 ASN A  97
ASP A 161
ARG A 207
 C2F  A3000 (-3.0A)
C2F  A3000 (-3.5A)
None
 0.48A 3k13A-4o1eA:
27.8		 3k13A-4o1eA:
29.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfr TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Rhodobacter
sphaeroides) 		PF03480
(DctP) 		3 ASN A  65
ASP A  32
ARG A 166
 None
None
MLT  A 401 (-3.1A)
 0.56A 3k13A-4pfrA:
undetectable		 3k13A-4pfrA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rgg PUTATIVE PHAGE
STRUCTURAL PROTEIN

(Lactococcus
phage 1358) 		no annotation 3 ASN A 206
ASP A 235
ARG A 132
 None
 0.93A 3k13A-4rggA:
undetectable		 3k13A-4rggA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rjw PORIN O

(Pseudomonas
aeruginosa) 		PF07396
(Porin_O_P) 		3 ASN A 205
ASP A 116
ARG A 313
 None
 0.80A 3k13A-4rjwA:
undetectable		 3k13A-4rjwA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru4 TAIL SPIKE PROTEIN
GP49

(Pseudomonas
virus LKA1) 		PF13229
(Beta_helix) 		3 ASN A 430
ASP A 433
ARG A 329
 None
 0.90A 3k13A-4ru4A:
undetectable		 3k13A-4ru4A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8y CRISPR SYSTEM CMR
SUBUNIT CMR2

(Pyrococcus
furiosus) 		PF12469
(DUF3692) 		3 ASN A 735
ASP A 600
ARG A 223
 None
MN  A 904 (-2.5A)
None
 0.93A 3k13A-4w8yA:
undetectable		 3k13A-4w8yA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xaa PUTATIVE OXYGENASE

(Streptomyces
viridochromogenes) 		PF05721
(PhyH) 		3 ASN A 150
ASP A 144
ARG A  66
 None
 0.79A 3k13A-4xaaA:
undetectable		 3k13A-4xaaA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xib E3 UBIQUITIN-PROTEIN
LIGASE MIB1

(Homo sapiens) 		PF00569
(ZZ)
PF06701
(MIB_HERC2) 		3 ASN A 253
ASP A 116
ARG A 149
 None
 0.74A 3k13A-4xibA:
undetectable		 3k13A-4xibA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zhs ASPARTATE
SEMIALDEHYDE
DEHYDROGENASE

(Trichophyton
rubrum) 		no annotation 3 ASN D 112
ASP D  90
ARG D 244
 None
 0.84A 3k13A-4zhsD:
undetectable		 3k13A-4zhsD:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BONTOXILYSIN A
BOTULINUM NEUROTOXIN
TYPE E,
NONTOXIC-NONHEMAGGLU
TININ COMPONENT,
NTNH

(Clostridium
botulinum;
Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07951
(Toxin_R_bind_C)
PF07952
(Toxin_trans)
PF07953
(Toxin_R_bind_N)
PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		3 ASN B 623
ASP B 773
ARG A1040
 None
 0.88A 3k13A-4zktB:
undetectable		 3k13A-4zktB:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a55 ENDO-ALPHA-N-ACETYLG
ALACTOSAMINIDASE

(Streptococcus
pneumoniae) 		PF12905
(Glyco_hydro_101)
PF17451
(Glyco_hyd_101C) 		3 ASN A 874
ASP A1013
ARG A1094
 None
 0.91A 3k13A-5a55A:
5.0		 3k13A-5a55A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aw4 NA, K-ATPASE ALPHA
SUBUNIT

(Squalus
acanthias) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF13246
(Cation_ATPase) 		3 ASN A 720
ASP A 376
ARG A 551
 MF4  A2001 (-3.4A)
MF4  A2001 ( 2.4A)
None
 0.93A 3k13A-5aw4A:
undetectable		 3k13A-5aw4A:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bpk GAMMA-GLUTAMYLTRANSP
EPTIDASE (GGT)

(Helicobacter
pylori) 		PF01019
(G_glu_transpept) 		3 ASN C 418
ASP C 422
ARG C 513
 None
4UD  C 701 ( 3.0A)
None
 0.85A 3k13A-5bpkC:
undetectable		 3k13A-5bpkC:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csl ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00289
(Biotin_carb_N)
PF00364
(Biotin_lipoyl)
PF01039
(Carboxyl_trans)
PF02785
(Biotin_carb_C)
PF02786
(CPSase_L_D2)
PF08326
(ACC_central) 		3 ASN A1319
ASP A1367
ARG A1348
 None
 0.93A 3k13A-5cslA:
undetectable		 3k13A-5cslA:
10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cx8 LIPOPROTEIN RAGB

(Porphyromonas
gingivalis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		3 ASN A 284
ASP A 281
ARG A 162
 None
 0.90A 3k13A-5cx8A:
undetectable		 3k13A-5cx8A:
24.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e7j ATP-DEPENDENT RNA
HELICASE DDX3X

(Homo sapiens) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 ASN A 509
ASP A 354
ARG A 407
 None
 0.91A 3k13A-5e7jA:
undetectable		 3k13A-5e7jA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewt EXODEOXYRIBONUCLEASE
III XTH

(Sulfolobus
islandicus) 		PF03372
(Exo_endo_phos) 		3 ASN A 146
ASP A 213
ARG A  12
 None
 0.90A 3k13A-5ewtA:
undetectable		 3k13A-5ewtA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h53 SKELETAL MUSCLE
MYOSIN HEAVY CHAIN
MYHC-EO/IIL

(Oryctolagus
cuniculus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		3 ASN A 424
ASP A 601
ARG A 245
 None
 0.83A 3k13A-5h53A:
undetectable		 3k13A-5h53A:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hgr ORANGE CAROTENOID
PROTEIN (OCP)

(Nostoc sp. PCC
7120) 		PF02136
(NTF2)
PF09150
(Carot_N) 		3 ASN A  29
ASP A 160
ARG A   9
 None
 0.87A 3k13A-5hgrA:
undetectable		 3k13A-5hgrA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jcf MELANOMA
DIFFERENTIATION
ASSOCIATED PROTEIN-5

(Gallus gallus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF11648
(RIG-I_C-RD) 		3 ASN A 357
ASP A 435
ARG A 753
 None
 0.93A 3k13A-5jcfA:
undetectable		 3k13A-5jcfA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
3, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
2, MITOCHONDRIAL

(Bos taurus;
Bos taurus) 		PF00329
(Complex1_30kDa)
PF00346
(Complex1_49kDa) 		3 ASN D 149
ASP D 107
ARG C 104
 None
 0.86A 3k13A-5lc5D:
undetectable		 3k13A-5lc5D:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m3x ANGIOTENSINOGEN

(Homo sapiens) 		no annotation 3 ASN A 246
ASP A 358
ARG A 385
 None
 0.92A 3k13A-5m3xA:
undetectable		 3k13A-5m3xA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mzs FERRIC ENTEROBACTIN
RECEPTOR

(Pseudomonas
aeruginosa) 		no annotation 3 ASN A 208
ASP A 203
ARG A  52
 None
 0.84A 3k13A-5mzsA:
undetectable		 3k13A-5mzsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n6w RETINOSCHISIN

(Homo sapiens) 		PF00754
(F5_F8_type_C) 		3 ASN A  85
ASP A 118
ARG A 156
 None
 0.87A 3k13A-5n6wA:
undetectable		 3k13A-5n6wA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nbs BETA-GLUCOSIDASE

(Neurospora
crassa) 		no annotation 3 ASN A 450
ASP A 432
ARG A 368
 None
 0.90A 3k13A-5nbsA:
3.3		 3k13A-5nbsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nug CYTOPLASMIC DYNEIN 1
HEAVY CHAIN 1

(Homo sapiens) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		3 ASN A2667
ASP A2717
ARG A2511
 None
 0.80A 3k13A-5nugA:
undetectable		 3k13A-5nugA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ols RHAMNOGALACTURONAN
LYASE

(Bacteroides
thetaiotaomicron) 		no annotation 3 ASN A 324
ASP A 280
ARG A 125
 RAM  A 607 (-2.8A)
CA  A 602 ( 3.2A)
ADA  A 604 ( 3.0A)
 0.87A 3k13A-5olsA:
undetectable		 3k13A-5olsA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ovl 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG

(Mycolicibacterium
smegmatis) 		no annotation 3 ASN A 160
ASP A 102
ARG A  33
 None
None
NAP  A1001 (-3.3A)
 0.89A 3k13A-5ovlA:
undetectable		 3k13A-5ovlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tum TETRACYCLINE
DESTRUCTASE TET(56)

(Legionella
longbeachae) 		PF01494
(FAD_binding_3) 		3 ASN A 209
ASP A 211
ARG A  49
 None
 0.91A 3k13A-5tumA:
undetectable		 3k13A-5tumA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5txe ATXE2

(Asticcacaulis
excentricus) 		PF00326
(Peptidase_S9) 		3 ASN A 127
ASP A  48
ARG A 321
 None
 0.91A 3k13A-5txeA:
2.2		 3k13A-5txeA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue8 PROTEIN UNC-13
HOMOLOG A

(Rattus
norvegicus) 		PF00130
(C1_1)
PF00168
(C2)
PF06292
(DUF1041)
PF10540
(Membr_traf_MHD) 		3 ASN A1371
ASP A1366
ARG A1401
 None
 0.89A 3k13A-5ue8A:
undetectable		 3k13A-5ue8A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vop 5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE

(Thermus
thermophilus) 		no annotation 3 ASN A 464
ASP A 531
ARG A 583
 C2F  A3001 (-2.2A)
C2F  A3001 (-2.5A)
C2F  A3001 (-3.0A)
 0.19A 3k13A-5vopA:
39.5		 3k13A-5vopA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wx4 ALKYLQUINOLONE
SYNTHASE

(Tetradium
ruticarpum) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		3 ASN A 342
ASP A 198
ARG A 178
 None
 0.88A 3k13A-5wx4A:
undetectable		 3k13A-5wx4A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ybb TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT
RESTRICTION
ENDONUCLEASE S
SUBUNITS

(Caldanaerobacter
subterraneus;
Caldanaerobacter
subterraneus) 		no annotation
no annotation 		3 ASN D 287
ASP D 254
ARG A 375
 None
 0.83A 3k13A-5ybbD:
undetectable		 3k13A-5ybbD:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cey BIFUNCTIONAL AAC/APH

(Staphylococcus
aureus) 		no annotation 3 ASN A 378
ASP A 374
ARG A 475
 None
GNP  A 500 (-4.6A)
None
 0.92A 3k13A-6ceyA:
undetectable		 3k13A-6ceyA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ejb XYLOSYLTRANSFERASE 1

(Homo sapiens) 		no annotation 3 ASN A 421
ASP A 426
ARG A 557
 None
 0.85A 3k13A-6ejbA:
undetectable		 3k13A-6ejbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoq DIPEPTIDYL PEPTIDASE
9

(Homo sapiens) 		no annotation 3 ASN A 810
ASP A 763
ARG A 354
 None
 0.82A 3k13A-6eoqA:
undetectable		 3k13A-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eot DIPEPTIDYL PEPTIDASE
8

(Homo sapiens) 		no annotation 3 ASN A 835
ASP A 788
ARG A 380
 None
 0.87A 3k13A-6eotA:
undetectable		 3k13A-6eotA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6etz BETA-GALACTOSIDASE

(Arthrobacter
sp. 32cB) 		no annotation 3 ASN A 791
ASP A 955
ARG A 771
 None
 0.92A 3k13A-6etzA:
6.3		 3k13A-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fah CAFFEYL-COA
REDUCTASE-ETF
COMPLEX SUBUNIT CARC

(Acetobacterium
woodii) 		no annotation 3 ASN C 310
ASP C 239
ARG C 178
 None
 0.59A 3k13A-6fahC:
undetectable		 3k13A-6fahC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fq3 E3 UBIQUITIN-PROTEIN
LIGASE TRIM71

(Danio rerio) 		no annotation 3 ASN A 584
ASP A 629
ARG A 799
 None
C  B   7 ( 2.5A)
None
 0.90A 3k13A-6fq3A:
undetectable		 3k13A-6fq3A:
undetectable