SIMILAR PATTERNS OF AMINO ACIDS FOR 3JB3_A_SAMA1101

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bkh MUCONATE LACTONIZING
ENZYME


(Pseudomonas
putida)
PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C)
5 GLU A 364
GLU A  46
VAL A  14
ASP A  10
ILE A  12
None
1.45A 3jb3A-1bkhA:
3.2
3jb3A-1bkhA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1htq GLUTAMINE SYNTHETASE

(Mycobacterium
tuberculosis)
PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N)
5 ASN A 106
VAL A  17
ASP A  70
ILE A  87
ASN A  88
None
1.44A 3jb3A-1htqA:
0.0
3jb3A-1htqA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n81 PLASMODIUM
FALCIPARUM GAMETE
ANTIGEN 27/25


(Plasmodium
falciparum)
PF09216
(Pfg27)
5 GLU A  42
GLU A 129
ARG A  34
VAL A 194
ASN A  96
None
1.09A 3jb3A-1n81A:
0.0
3jb3A-1n81A:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p75 THYMIDINE KINASE

(Equid
alphaherpesvirus
4)
PF00693
(Herpes_TK)
5 GLU A 257
VAL A 142
ILE A 179
ASN A 178
GLU A 173
None
1.47A 3jb3A-1p75A:
0.0
3jb3A-1p75A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pxy FIMBRIN-LIKE PROTEIN

(Arabidopsis
thaliana)
PF00307
(CH)
5 GLU A 395
VAL A 427
ASP A 417
ILE A 423
GLU A 426
None
1.38A 3jb3A-1pxyA:
0.0
3jb3A-1pxyA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q51 MENB

(Mycobacterium
tuberculosis)
PF00378
(ECH_1)
5 ASN A  18
GLU A 240
VAL A  72
ASN A  53
GLU A  68
None
1.41A 3jb3A-1q51A:
0.7
3jb3A-1q51A:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfx PROTEIN (PH 2.5 ACID
PHOSPHATASE)


(Aspergillus
niger)
PF00328
(His_Phos_2)
5 SER A 449
GLU A 159
GLU A 455
ASP A 460
ILE A 181
None
GOL  A 702 (-3.2A)
None
None
None
1.27A 3jb3A-1qfxA:
0.0
3jb3A-1qfxA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qhx PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)


(Streptomyces
venezuelae)
PF07931
(CPT)
5 GLU A  72
VAL A 114
ASP A  93
ILE A   7
ASN A   9
None
1.29A 3jb3A-1qhxA:
1.9
3jb3A-1qhxA:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tqy ACTINORHODIN
POLYKETIDE PUTATIVE
BETA-KETOACYL
SYNTHASE 1


(Streptomyces
coelicolor)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
5 ASN A 316
SER A 403
MET A 285
ILE A 306
ASN A 307
None
None
None
None
MG  A1095 (-3.1A)
1.47A 3jb3A-1tqyA:
0.0
3jb3A-1tqyA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6j LANOSTEROL SYNTHASE

(Homo sapiens)
PF13243
(SQHop_cyclase_C)
PF13249
(SQHop_cyclase_N)
5 GLU A 555
GLU A 558
ARG A 552
VAL A 537
ASN A 492
None
1.50A 3jb3A-1w6jA:
undetectable
3jb3A-1w6jA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wn1 DIPEPTIDASE

(Pyrococcus
horikoshii)
PF00557
(Peptidase_M24)
PF01321
(Creatinase_N)
5 GLU A 319
ARG A 351
VAL A 258
ASP A 335
ILE A 336
CO  A1001 (-2.6A)
None
None
None
None
1.28A 3jb3A-1wn1A:
undetectable
3jb3A-1wn1A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zao RIO2 SERINE KINASE

(Archaeoglobus
fulgidus)
PF01163
(RIO1)
PF09202
(Rio2_N)
5 ASN A 153
SER A 239
ILE A 234
ASN A 223
GLU A 186
None
None
ATP  A 286 (-4.5A)
MN  A 283 (-2.8A)
ATP  A 286 (-3.5A)
1.46A 3jb3A-1zaoA:
undetectable
3jb3A-1zaoA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfs MYOSIN-5A

(Gallus gallus)
PF00063
(Myosin_head)
PF00612
(IQ)
5 ASN A 208
SER A 218
ASP A 437
ILE A 224
GLU A 225
None
1.42A 3jb3A-2dfsA:
undetectable
3jb3A-2dfsA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lbw H/ACA
RIBONUCLEOPROTEIN
COMPLEX SUBUNIT 2


(Saccharomyces
cerevisiae)
PF01248
(Ribosomal_L7Ae)
5 ASN A 130
GLU A  71
VAL A  76
ILE A 125
ASN A  55
None
1.49A 3jb3A-2lbwA:
undetectable
3jb3A-2lbwA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lbw H/ACA
RIBONUCLEOPROTEIN
COMPLEX SUBUNIT 2


(Saccharomyces
cerevisiae)
PF01248
(Ribosomal_L7Ae)
5 ASN A 130
GLU A  71
VAL A 123
ILE A 125
ASN A  55
None
1.36A 3jb3A-2lbwA:
undetectable
3jb3A-2lbwA:
8.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mt4 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSA


(Bacillus
subtilis)
PF08529
(NusA_N)
5 GLU A   4
VAL A 118
ASP A   7
ILE A  11
GLU A  15
None
1.23A 3jb3A-2mt4A:
2.0
3jb3A-2mt4A:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr5 GLYCOGEN OPERON
PROTEIN GLGX


(Sulfolobus
solfataricus)
PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48)
5 SER A  22
VAL A 146
ASP A 107
ILE A 106
ASN A 248
None
1.05A 3jb3A-2vr5A:
0.9
3jb3A-2vr5A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxo GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]


(Homo sapiens)
PF00117
(GATase)
PF00958
(GMP_synt_C)
PF02540
(NAD_synthase)
5 SER A 280
VAL A 351
ASP A 271
ILE A 297
ASN A 298
None
1.42A 3jb3A-2vxoA:
1.2
3jb3A-2vxoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yfn ALPHA-GALACTOSIDASE-
SUCROSE KINASE AGASK


([Ruminococcus]
gnavus)
PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N)
5 ASN A 276
SER A 258
GLU A 277
ILE A  88
ASN A  87
None
1.23A 3jb3A-2yfnA:
undetectable
3jb3A-2yfnA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ab4 ASPARTOKINASE
ASPARTOKINASE


(Corynebacterium
glutamicum;
Corynebacterium
glutamicum)
PF00696
(AA_kinase)
PF01842
(ACT)
PF13840
(ACT_7)
PF01842
(ACT)
PF13840
(ACT_7)
5 SER A 302
VAL B  33
ASP B  60
ILE B  23
GLU B  29
None
None
None
THR  B 201 ( 4.7A)
None
1.37A 3jb3A-3ab4A:
undetectable
3jb3A-3ab4A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3baz HYDROXYPHENYLPYRUVAT
E REDUCTASE


(Plectranthus
scutellarioides)
PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
5 GLU A 259
VAL A 201
ASP A 237
ILE A 213
ASN A 214
None
1.36A 3jb3A-3bazA:
3.6
3jb3A-3bazA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3byh FIMBRIN ABD2

(Homo sapiens)
PF00307
(CH)
5 GLU B 395
VAL B 427
ASP B 417
ILE B 423
GLU B 426
None
1.37A 3jb3A-3byhB:
undetectable
3jb3A-3byhB:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cnj CHOLESTEROL OXIDASE

(Streptomyces
sp. SA-COO)
PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C)
5 ASN A 221
SER A 211
ARG A  64
ARG A  87
VAL A  85
None
1.44A 3jb3A-3cnjA:
undetectable
3jb3A-3cnjA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ff1 GLUCOSE-6-PHOSPHATE
ISOMERASE


(Staphylococcus
aureus)
PF00342
(PGI)
5 ASN A 357
GLU A 269
VAL A 391
ILE A 380
ASN A 379
None
1.30A 3jb3A-3ff1A:
undetectable
3jb3A-3ff1A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3obw PROTEIN PELOTA
HOMOLOG


(Sulfolobus
solfataricus)
PF03463
(eRF1_1)
PF03465
(eRF1_3)
5 GLU A 278
VAL A 285
ASP A 308
ILE A 309
ASN A 311
None
1.37A 3jb3A-3obwA:
undetectable
3jb3A-3obwA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r3s OXIDOREDUCTASE

(Salmonella
enterica)
PF13561
(adh_short_C2)
5 GLU A  85
VAL A  76
ASP A  58
ILE A  78
ASN A  79
None
None
MG  A 296 ( 2.5A)
None
NAD  A 300 ( 4.1A)
1.46A 3jb3A-3r3sA:
4.0
3jb3A-3r3sA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uvj GUANYLATE CYCLASE
SOLUBLE SUBUNIT
ALPHA-3


(Homo sapiens)
PF00211
(Guanylate_cyc)
5 ASN A 605
GLU A 608
ARG A 574
ASP A 530
ILE A 487
None
1.33A 3jb3A-3uvjA:
undetectable
3jb3A-3uvjA:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zo0 E3 UBIQUITIN-PROTEIN
LIGASE TRIM21


(Mus musculus)
PF00622
(SPRY)
PF13765
(PRY)
5 ASN B  19
SER B  20
ARG B  87
ASP B  42
ASN B  43
None
1.48A 3jb3A-3zo0B:
undetectable
3jb3A-3zo0B:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bfr PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC S
SUBUNIT BETA ISOFORM


(Mus musculus)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
5 GLU A 249
ARG A 247
VAL A 193
ILE A 263
ASN A 265
None
1.35A 3jb3A-4bfrA:
undetectable
3jb3A-4bfrA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4crm TRANSLATION
INITIATION FACTOR
RLI1


(Saccharomyces
cerevisiae)
PF00005
(ABC_tran)
PF00037
(Fer4)
PF04068
(RLI)
5 ARG P 475
VAL P 476
ASP P 458
ILE P 457
GLU P 472
None
1.38A 3jb3A-4crmP:
undetectable
3jb3A-4crmP:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e4j ARGININE DEIMINASE

(Mycoplasma
penetrans)
PF02274
(Amidinotransf)
5 GLU A 257
VAL A 285
ASP A 260
ILE A 271
ASN A 273
None
1.47A 3jb3A-4e4jA:
undetectable
3jb3A-4e4jA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ipn 6-PHOSPHO-BETA-GLUCO
SIDASE


(Streptococcus
pneumoniae)
PF00232
(Glyco_hydro_1)
5 GLU B  20
ARG B 158
VAL B 155
ILE B  88
ASN B  98
None
1.15A 3jb3A-4ipnB:
0.8
3jb3A-4ipnB:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mz0 CURL

(Moorea
producens)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc)
5 SER A 827
GLU A 824
ARG A 840
VAL A 839
ASN A 833
None
1.43A 3jb3A-4mz0A:
2.1
3jb3A-4mz0A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o3x TRANSFERRIN BINDING
PROTEIN B


(Actinobacillus
pleuropneumoniae)
PF01298
(TbpB_B_D)
PF17484
(TbpB_A)
5 ASN B 244
SER B 247
VAL B  51
ILE B  65
ASN B 150
None
1.33A 3jb3A-4o3xB:
undetectable
3jb3A-4o3xB:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p72 PHENYLALANINE--TRNA
LIGASE BETA SUBUNIT


(Pseudomonas
aeruginosa)
PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5)
5 SER A 324
ARG A 308
VAL A 275
ASP A 267
ILE A 271
None
1.46A 3jb3A-4p72A:
undetectable
3jb3A-4p72A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pd3 NONMUSCLE MYOSIN
HEAVY CHAIN B,
ALPHA-ACTININ A
CHIMERA PROTEIN


(Homo sapiens;
Dictyostelium
discoideum)
PF00063
(Myosin_head)
PF00435
(Spectrin)
PF02736
(Myosin_N)
5 ASN A 230
SER A 240
VAL A 191
ASP A 459
ILE A 457
None
1.41A 3jb3A-4pd3A:
undetectable
3jb3A-4pd3A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxw CARCINOEMBRYONIC
ANTIGEN-RELATED CELL
ADHESION MOLECULE 1


(Homo sapiens)
PF07686
(V-set)
5 ASN A  61
SER A  62
ARG A  43
ASP A  82
ASN A  81
None
None
MLA  A 201 (-2.8A)
None
None
1.42A 3jb3A-4qxwA:
undetectable
3jb3A-4qxwA:
7.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8e 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2


(Yersinia pestis)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
5 MET A 390
VAL A 318
ILE A 300
ASN A 301
GLU A 314
None
1.26A 3jb3A-4r8eA:
undetectable
3jb3A-4r8eA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tym PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE


(Streptococcus
agalactiae)
PF01048
(PNP_UDP_1)
5 VAL A 126
ASP A 226
ILE A 224
ASN A 227
GLU A 124
None
1.48A 3jb3A-4tymA:
undetectable
3jb3A-4tymA:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uir OLEATE HYDRATASE

(Elizabethkingia
meningoseptica)
PF06100
(MCRA)
5 ASN A 575
GLU A 551
ARG A 524
VAL A 525
ILE A 559
None
1.26A 3jb3A-4uirA:
2.9
3jb3A-4uirA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xul MG662

(Megavirus
chiliensis)
no annotation 5 ARG A  53
ARG A  30
VAL A  29
ASP A  61
ILE A  62
None
None
None
MG  A 402 (-2.4A)
None
1.46A 3jb3A-4xulA:
undetectable
3jb3A-4xulA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b01 MOEN5

(Streptomyces
viridosporus)
no annotation 5 ASN A 193
GLU A 195
ARG A 256
VAL A 214
ASP A 185
None
1.46A 3jb3A-5b01A:
undetectable
3jb3A-5b01A:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c54 DIHYDRODIPICOLINATE
SYNTHASE/N-ACETYLNEU
RAMINATE LYASE


(Corynebacterium
glutamicum)
PF00701
(DHDPS)
5 SER A  49
MET A  14
GLU A 198
VAL A 305
ILE A 252
GOL  A 401 ( 3.7A)
None
GOL  A 401 (-2.7A)
None
None
1.21A 3jb3A-5c54A:
1.3
3jb3A-5c54A:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c8g PP-BRD20

(Trypanosoma
brucei)
PF00439
(Bromodomain)
5 ASN A  95
ARG A 121
ASP A  88
ILE A  85
ASN A  87
None
1.22A 3jb3A-5c8gA:
undetectable
3jb3A-5c8gA:
10.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lox PEPTIDASE

(Pseudomonas
aeruginosa)
no annotation 5 SER A 223
ARG A  19
VAL A 186
ASP A 177
ILE A 180
None
1.42A 3jb3A-5loxA:
undetectable
3jb3A-5loxA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tv2 ELONGATION FACTOR G

(Vibrio
vulnificus)
PF00009
(GTP_EFTU)
PF03144
(GTP_EFTU_D2)
5 GLU A 284
GLU A 245
VAL A 167
ASP A 184
ILE A 169
None
1.46A 3jb3A-5tv2A:
undetectable
3jb3A-5tv2A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u5g 6-PHOSPHOGLUCONATE
DEHYDROGENASE


(Pseudomonas
syringae)
PF03446
(NAD_binding_2)
PF14833
(NAD_binding_11)
5 GLU A 144
VAL A 139
ASP A 117
ILE A 119
GLU A 120
None
1.48A 3jb3A-5u5gA:
undetectable
3jb3A-5u5gA:
15.40