SIMILAR PATTERNS OF AMINO ACIDS FOR 3JB2_A_SAMA1101_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b0k PROTEIN (ACONITASE)

(Sus scrofa) 		PF00330
(Aconitase)
PF00694
(Aconitase_C) 		3 GLU A 723
ASP A 695
ASP A 687
 None
 0.77A 3jb2A-1b0kA:
0.0		 3jb2A-1b0kA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dmg RIBOSOMAL PROTEIN L4

(Thermotoga
maritima) 		PF00573
(Ribosomal_L4) 		3 GLU A 161
ASP A 183
ASP A 216
 None
CIT  A 510 (-2.9A)
None
 0.63A 3jb2A-1dmgA:
undetectable		 3jb2A-1dmgA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ev1 ECHOVIRUS 1
ECHOVIRUS 1

(Enterovirus B;
Enterovirus B) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 GLU 1  65
ASP 3  18
ASP 1 116
 None
 0.74A 3jb2A-1ev11:
undetectable		 3jb2A-1ev11:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvf TAGATOSE-BISPHOSPHAT
E ALDOLASE AGAY

(Escherichia
coli) 		PF01116
(F_bP_aldolase) 		3 GLU A 196
ASP A 190
ASP A 156
 EDO  A1291 (-3.3A)
EDO  A1291 (-2.6A)
None
 0.57A 3jb2A-1gvfA:
0.0		 3jb2A-1gvfA:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcz BETA-METHYLASPARTASE

(Clostridium
tetanomorphum) 		PF05034
(MAAL_N)
PF07476
(MAAL_C) 		3 GLU A 188
ASP A 190
ASP A 230
 None
 0.67A 3jb2A-1kczA:
0.1		 3jb2A-1kczA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ldn L-LACTATE
DEHYDROGENASE

(Geobacillus
stearothermophilus) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		3 GLU A  47
ASP A  90
ASP A  85
 None
 0.78A 3jb2A-1ldnA:
0.0		 3jb2A-1ldnA:
14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mqt POLYPROTEIN
POLYPROTEIN CAPSID
PROTEIN

(Enterovirus B;
Enterovirus B) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 GLU A  65
ASP C  18
ASP A 115
 None
 0.59A 3jb2A-1mqtA:
0.0		 3jb2A-1mqtA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n7r HYALURONIDASE

(Streptococcus
pneumoniae) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		3 GLU A 454
ASP A 508
ASP A 600
 None
 0.66A 3jb2A-1n7rA:
2.7		 3jb2A-1n7rA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nlf REGULATORY PROTEIN
REPA

(Escherichia
coli) 		PF13481
(AAA_25) 		3 GLU A 132
ASP A 169
ASP A 125
 None
 0.62A 3jb2A-1nlfA:
4.8		 3jb2A-1nlfA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf7 PROTEIN (CATALASE
HPII)

(Escherichia
coli) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 GLU A 503
ASP A 350
ASP A 355
 None
 0.77A 3jb2A-1qf7A:
undetectable		 3jb2A-1qf7A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qys TOP7

(-) 		no annotation 3 GLU A  59
ASP A  86
ASP A   3
 None
 0.69A 3jb2A-1qysA:
3.8		 3jb2A-1qysA:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r1a HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP1)
HUMAN RHINOVIRUS 1A
COAT PROTEIN
(SUBUNIT VP3)

(Rhinovirus A;
Rhinovirus A) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 GLU 1  68
ASP 3  18
ASP 1 122
 None
 0.64A 3jb2A-1r1a1:
undetectable		 3jb2A-1r1a1:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rhi HUMAN RHINOVIRUS 3
COAT PROTEIN
HUMAN RHINOVIRUS 3
COAT PROTEIN

(Rhinovirus B;
Rhinovirus B) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 GLU 1  68
ASP 3  18
ASP 1 125
 None
 0.61A 3jb2A-1rhi1:
undetectable		 3jb2A-1rhi1:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rzv GLYCOGEN SYNTHASE 1

(Agrobacterium
tumefaciens) 		PF00534
(Glycos_transf_1)
PF08323
(Glyco_transf_5) 		3 GLU A   9
ASP A 138
ASP A  21
 None
 0.76A 3jb2A-1rzvA:
2.6		 3jb2A-1rzvA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s5k AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE

(Salmonella
enterica) 		PF00583
(Acetyltransf_1) 		3 GLU A  79
ASP A 115
ASP A  65
 None
 0.78A 3jb2A-1s5kA:
undetectable		 3jb2A-1s5kA:
9.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sro PNPASE

(Escherichia
coli) 		PF00575
(S1) 		3 GLU A  44
ASP A  48
ASP A  18
 None
 0.65A 3jb2A-1sroA:
undetectable		 3jb2A-1sroA:
7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tht THIOESTERASE

(Vibrio harveyi) 		PF02273
(Acyl_transf_2) 		3 GLU A 122
ASP A 126
ASP A 194
 None
 0.77A 3jb2A-1thtA:
undetectable		 3jb2A-1thtA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vfg POLY A POLYMERASE

(Aquifex
aeolicus) 		PF01743
(PolyA_pol) 		3 GLU A  81
ASP A 100
ASP A 105
 None
None
APC  A 500 (-3.6A)
 0.60A 3jb2A-1vfgA:
undetectable		 3jb2A-1vfgA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aaa ALPHA-AMYLASE

(Aspergillus
niger) 		PF00128
(Alpha-amylase)
PF09260
(DUF1966) 		3 GLU A 230
ASP A 117
ASP A 121
 CA  A 486 (-2.5A)
None
CA  A 485 (-3.2A)
 0.66A 3jb2A-2aaaA:
undetectable		 3jb2A-2aaaA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aff ANTIGEN KI-67
MKI67 FHA DOMAIN
INTERACTING
NUCLEOLAR
PHOSPHOPROTEIN

(Homo sapiens;
Homo sapiens) 		PF00498
(FHA)
PF12196
(hNIFK_binding) 		3 GLU B 260
ASP B 256
ASP A  92
 None
 0.70A 3jb2A-2affB:
undetectable		 3jb2A-2affB:
4.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bdw HYPOTHETICAL PROTEIN
K11E8.1D

(Caenorhabditis
elegans) 		PF00069
(Pkinase) 		3 GLU A 236
ASP A 238
ASP A 231
 None
 0.69A 3jb2A-2bdwA:
undetectable		 3jb2A-2bdwA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d89 EHBP1 PROTEIN

(Homo sapiens) 		PF00307
(CH) 		3 GLU A  67
ASP A  56
ASP A  74
 None
 0.70A 3jb2A-2d89A:
undetectable		 3jb2A-2d89A:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e6s E3 UBIQUITIN-PROTEIN
LIGASE UHRF2

(Homo sapiens) 		PF00628
(PHD) 		3 GLU A  12
ASP A  14
ASP A  19
 None
 0.75A 3jb2A-2e6sA:
undetectable		 3jb2A-2e6sA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f1n CYTOLETHAL
DISTENDING TOXIN
SUBUNIT B

(Escherichia
coli) 		PF03372
(Exo_endo_phos) 		3 GLU A  44
ASP A 174
ASP A 242
 None
 0.76A 3jb2A-2f1nA:
undetectable		 3jb2A-2f1nA:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fpg SUCCINYL-COA LIGASE
[GDP-FORMING]
BETA-CHAIN,
MITOCHONDRIAL

(Sus scrofa) 		PF00549
(Ligase_CoA)
PF08442
(ATP-grasp_2) 		3 GLU B 204
ASP B 220
ASP B 139
 None
K  B 396 ( 3.6A)
None
 0.56A 3jb2A-2fpgB:
2.9		 3jb2A-2fpgB:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fvm DIHYDROPYRIMIDINASE

(Lachancea
kluyveri) 		PF01979
(Amidohydro_1) 		3 GLU A 112
ASP A 101
ASP A 119
 None
 0.77A 3jb2A-2fvmA:
undetectable		 3jb2A-2fvmA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jjf L-LYSINE EPSILON
AMINOTRANSFERASE

(Mycobacterium
tuberculosis) 		PF00202
(Aminotran_3) 		3 GLU A 315
ASP A 294
ASP A 265
 None
 0.69A 3jb2A-2jjfA:
undetectable		 3jb2A-2jjfA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o34 HYPOTHETICAL PROTEIN

(Desulfovibrio
vulgaris) 		no annotation 3 GLU A 245
ASP A 243
ASP A 138
 None
 0.75A 3jb2A-2o34A:
undetectable		 3jb2A-2o34A:
12.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5v DNA REPLICATION AND
REPAIR PROTEIN RECF

(Deinococcus
radiodurans) 		PF02463
(SMC_N) 		3 GLU A 119
ASP A 120
ASP A  55
 None
 0.74A 3jb2A-2o5vA:
undetectable		 3jb2A-2o5vA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ofk 3-METHYLADENINE DNA
GLYCOSYLASE I,
CONSTITUTIVE

(Salmonella
enterica) 		PF03352
(Adenine_glyco) 		3 GLU A 106
ASP A 114
ASP A  27
 None
PGE  A 904 (-4.0A)
None
 0.75A 3jb2A-2ofkA:
undetectable		 3jb2A-2ofkA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p1r LIPID KINASE YEGS

(Salmonella
enterica) 		PF00781
(DAGK_cat) 		3 GLU A 281
ASP A 257
ASP A 131
 None
 0.65A 3jb2A-2p1rA:
undetectable		 3jb2A-2p1rA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7c TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN

(Escherichia
coli) 		PF02384
(N6_Mtase)
PF12161
(HsdM_N) 		3 GLU B  42
ASP B 111
ASP B 114
 None
 0.73A 3jb2A-2y7cB:
5.8		 3jb2A-2y7cB:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ywo PROBABLE
THIOL-DISULFIDE
ISOMERASE/THIOREDOXI
N

(Thermus
thermophilus) 		PF00578
(AhpC-TSA) 		3 GLU A 104
ASP A 103
ASP A  75
 None
 0.70A 3jb2A-2ywoA:
undetectable		 3jb2A-2ywoA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zau SELENIDE, WATER
DIKINASE

(Aquifex
aeolicus) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		3 GLU A 112
ASP A  68
ASP A 119
 None
 0.63A 3jb2A-2zauA:
undetectable		 3jb2A-2zauA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwa LEUCINE CARBOXYL
METHYLTRANSFERASE 2

(Saccharomyces
cerevisiae) 		PF04072
(LCM)
PF13418
(Kelch_4) 		3 GLU A 314
ASP A 308
ASP A 363
 None
 0.77A 3jb2A-2zwaA:
8.4		 3jb2A-2zwaA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ab4 ASPARTOKINASE

(Corynebacterium
glutamicum) 		PF00696
(AA_kinase)
PF01842
(ACT)
PF13840
(ACT_7) 		3 GLU A 391
ASP A 395
ASP A 261
 None
 0.66A 3jb2A-3ab4A:
undetectable		 3jb2A-3ab4A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahm OLIGOPEPTIDASE

(Geobacillus sp.
MO-1) 		no annotation 3 GLU A 179
ASP A 463
ASP A 172
 None
 0.68A 3jb2A-3ahmA:
undetectable		 3jb2A-3ahmA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bhh CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II BETA
CHAIN

(Homo sapiens) 		PF00069
(Pkinase) 		3 GLU A 237
ASP A 239
ASP A 232
 None
 0.49A 3jb2A-3bhhA:
undetectable		 3jb2A-3bhhA:
14.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ce6 ADENOSYLHOMOCYSTEINA
SE

(Mycobacterium
tuberculosis) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		3 GLU A 374
ASP A 388
ASP A 365
 None
 0.63A 3jb2A-3ce6A:
undetectable		 3jb2A-3ce6A:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fj1 PUTATIVE
PHOSPHOSUGAR
ISOMERASE

(Ruegeria
pomeroyi) 		PF01380
(SIS) 		3 GLU A 320
ASP A  13
ASP A 193
 None
 0.68A 3jb2A-3fj1A:
undetectable		 3jb2A-3fj1A:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fot 15-O-ACETYLTRANSFERA
SE

(Fusarium
sporotrichioides) 		PF07428
(Tri3) 		3 GLU A 179
ASP A 136
ASP A 466
 None
 0.61A 3jb2A-3fotA:
undetectable		 3jb2A-3fotA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM

(Serratia
plymuthica) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 GLU A 124
ASP A  82
ASP A 195
 None
 0.67A 3jb2A-3gbdA:
undetectable		 3jb2A-3gbdA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gha DISULFIDE BOND
FORMATION PROTEIN D

(Bacillus
subtilis) 		PF13462
(Thioredoxin_4) 		3 GLU A 216
ASP A  86
ASP A 209
 None
 0.69A 3jb2A-3ghaA:
undetectable		 3jb2A-3ghaA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhc INTERLEUKIN-28B

(Homo sapiens) 		PF15177
(IL28A) 		3 GLU A  73
ASP A  77
ASP A  87
 None
 0.75A 3jb2A-3hhcA:
undetectable		 3jb2A-3hhcA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 2

(Manduca sexta) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		3 GLU A 239
ASP A 235
ASP A 646
 None
 0.76A 3jb2A-3hhsA:
undetectable		 3jb2A-3hhsA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjj MALTOSE
O-ACETYLTRANSFERASE

(Bacillus
anthracis) 		PF12464
(Mac)
PF14602
(Hexapep_2) 		3 GLU A 127
ASP A  17
ASP A  71
 ACY  A 188 ( 4.7A)
None
None
 0.71A 3jb2A-3hjjA:
undetectable		 3jb2A-3hjjA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibg ATPASE, SUBUNIT OF
THE GET COMPLEX

(Aspergillus
fumigatus) 		PF02374
(ArsA_ATPase) 		3 GLU A  93
ASP A 158
ASP A  70
 None
 0.78A 3jb2A-3ibgA:
undetectable		 3jb2A-3ibgA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ivu HOMOCITRATE
SYNTHASE,
MITOCHONDRIAL

(Schizosaccharomyces
pombe) 		PF00682
(HMGL-like) 		3 GLU A 161
ASP A 123
ASP A 220
 None
 0.60A 3jb2A-3ivuA:
undetectable		 3jb2A-3ivuA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j9e VP5

(Bluetongue
virus) 		PF00901
(Orbi_VP5) 		3 GLU D 103
ASP D 104
ASP D 226
 None
 0.76A 3jb2A-3j9eD:
undetectable		 3jb2A-3j9eD:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jvd TRANSCRIPTIONAL
REGULATORS

(Corynebacterium
glutamicum) 		PF13377
(Peripla_BP_3) 		3 GLU A 292
ASP A 299
ASP A  89
 None
 0.78A 3jb2A-3jvdA:
undetectable		 3jb2A-3jvdA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kl8 CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE II

(Caenorhabditis
elegans) 		PF00069
(Pkinase) 		3 GLU A 235
ASP A 237
ASP A 230
 None
 0.75A 3jb2A-3kl8A:
undetectable		 3jb2A-3kl8A:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l44 GLUTAMATE-1-SEMIALDE
HYDE 2,1-AMINOMUTASE
1

(Bacillus
anthracis) 		PF00202
(Aminotran_3) 		3 GLU A 286
ASP A 112
ASP A 264
 None
 0.77A 3jb2A-3l44A:
undetectable		 3jb2A-3l44A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3one ADENOSYLHOMOCYSTEINA
SE

(Lupinus luteus) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		3 GLU A 361
ASP A 376
ASP A 352
 None
 0.74A 3jb2A-3oneA:
undetectable		 3jb2A-3oneA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p27 ELONGATION FACTOR 1
ALPHA-LIKE PROTEIN

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3) 		3 GLU A 464
ASP A 466
ASP A 448
 None
 0.47A 3jb2A-3p27A:
undetectable		 3jb2A-3p27A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qxm GLUTAMATE RECEPTOR
IONOTROPIC, KAINATE
2

(Homo sapiens) 		PF10613
(Lig_chan-Glu_bd) 		3 GLU A 429
ASP A 434
ASP A 426
 None
 0.75A 3jb2A-3qxmA:
undetectable		 3jb2A-3qxmA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3soa CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER

(Homo sapiens) 		PF00069
(Pkinase)
PF08332
(CaMKII_AD) 		3 GLU A 236
ASP A 238
ASP A 231
 None
 0.66A 3jb2A-3soaA:
undetectable		 3jb2A-3soaA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3srz TOXIN A

(Clostridioides
difficile) 		PF12918
(TcdB_N)
PF12919
(TcdA_TcdB) 		3 GLU A 176
ASP A 180
ASP A 425
 None
 0.68A 3jb2A-3srzA:
undetectable		 3jb2A-3srzA:
20.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sut BETA-HEXOSAMINIDASE

(Paenibacillus
sp. TS12) 		PF00728
(Glyco_hydro_20)
PF02838
(Glyco_hydro_20b) 		3 GLU A 244
ASP A 237
ASP A 183
 None
 0.76A 3jb2A-3sutA:
undetectable		 3jb2A-3sutA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t9q STAGE II SPORULATION
PROTEIN E

(Bacillus
subtilis) 		PF07228
(SpoIIE) 		3 GLU A 729
ASP A 727
ASP A 681
 None
 0.69A 3jb2A-3t9qA:
undetectable		 3jb2A-3t9qA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufx SUCCINYL-COA
SYNTHETASE BETA
SUBUNIT

(Thermus
aquaticus) 		PF00549
(Ligase_CoA)
PF08442
(ATP-grasp_2) 		3 GLU B 188
ASP B 204
ASP B 124
 None
GDP  B 398 ( 3.5A)
None
 0.59A 3jb2A-3ufxB:
undetectable		 3jb2A-3ufxB:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vf1 11R-LIPOXYGENASE

(Gersemia
fruticosa) 		PF00305
(Lipoxygenase)
PF01477
(PLAT) 		3 GLU A  63
ASP A  29
ASP A 126
 None
 0.74A 3jb2A-3vf1A:
undetectable		 3jb2A-3vf1A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vr5 V-TYPE SODIUM ATPASE
CATALYTIC SUBUNIT A

(Enterococcus
hirae) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N)
PF16886
(ATP-synt_ab_Xtn) 		3 GLU A 381
ASP A 323
ASP A 206
 None
 0.78A 3jb2A-3vr5A:
undetectable		 3jb2A-3vr5A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x3y PHENYLETHYLAMINE
OXIDASE

(Arthrobacter
globiformis) 		PF01179
(Cu_amine_oxid)
PF02728
(Cu_amine_oxidN3) 		3 GLU A 482
ASP A 574
ASP A 578
 None
 0.64A 3jb2A-3x3yA:
undetectable		 3jb2A-3x3yA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zdb PROTEIN XNI

(Escherichia
coli) 		PF01367
(5_3_exonuc)
PF02739
(5_3_exonuc_N) 		3 GLU A 102
ASP A 105
ASP A 127
 MG  A1253 ( 4.9A)
None
None
 0.72A 3jb2A-3zdbA:
2.7		 3jb2A-3zdbA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b1m LEVANASE

(Bacillus
subtilis) 		PF06439
(DUF1080) 		3 GLU A 561
ASP A 563
ASP A 643
 None
 0.40A 3jb2A-4b1mA:
undetectable		 3jb2A-4b1mA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ew9 PECTATE LYASE

(Caldicellulosiruptor
bescii) 		PF03211
(Pectate_lyase) 		3 GLU A  39
ASP A  64
ASP A 107
 CA  A 204 (-2.2A)
CA  A 202 (-2.3A)
UNG  A 209 ( 3.3A)
 0.61A 3jb2A-4ew9A:
undetectable		 3jb2A-4ew9A:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4exr PUTATIVE LIPOPROTEIN

(Clostridioides
difficile) 		PF03413
(PepSY) 		3 GLU A 137
ASP A  83
ASP A 170
 None
NA  A 301 (-2.6A)
None
 0.53A 3jb2A-4exrA:
undetectable		 3jb2A-4exrA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hhr ALPHA-DIOXYGENASE

(Arabidopsis
thaliana) 		PF03098
(An_peroxidase) 		3 GLU A 170
ASP A 167
ASP A 467
 None
 0.73A 3jb2A-4hhrA:
undetectable		 3jb2A-4hhrA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hzu ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA 2
ENERGY-COUPLING
FACTOR TRANSPORTER
ATP-BINDING PROTEIN
ECFA 1

(Lactobacillus
brevis;
Lactobacillus
brevis) 		PF00005
(ABC_tran)
PF00005
(ABC_tran) 		3 GLU A 236
ASP A 214
ASP B 177
 None
 0.76A 3jb2A-4hzuA:
undetectable		 3jb2A-4hzuA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1d ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN

(Bradyrhizobium
diazoefficiens) 		PF13416
(SBP_bac_8) 		3 GLU A 215
ASP A 194
ASP A 169
 None
 0.77A 3jb2A-4i1dA:
undetectable		 3jb2A-4i1dA:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3g BETA-GLUCOSIDASE

(Streptomyces
venezuelae) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 GLU A  93
ASP A 145
ASP A  76
 None
 0.65A 3jb2A-4i3gA:
undetectable		 3jb2A-4i3gA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4idm DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00171
(Aldedh) 		3 GLU A 442
ASP A 446
ASP A 473
 None
 0.68A 3jb2A-4idmA:
3.4		 3jb2A-4idmA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0k TANNASE

(Lactobacillus
plantarum) 		no annotation 3 GLU A 357
ASP A 213
ASP A 421
 EGR  A 501 (-2.9A)
None
EGR  A 501 (-3.5A)
 0.72A 3jb2A-4j0kA:
undetectable		 3jb2A-4j0kA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nes UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Methanocaldococcus
jannaschii) 		PF02350
(Epimerase_2) 		3 GLU A 129
ASP A 124
ASP A 287
 UD1  A 400 (-3.6A)
None
None
 0.78A 3jb2A-4nesA:
2.4		 3jb2A-4nesA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p8i PROTEIN-GLUTAMINE
GAMMA-GLUTAMYLTRANSF
ERASE

(Bacillus
subtilis) 		no annotation 3 GLU A  48
ASP A 168
ASP A 236
 None
 0.74A 3jb2A-4p8iA:
undetectable		 3jb2A-4p8iA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q1t GLUTAMATE 5-KINASE

(Burkholderia
thailandensis) 		PF00696
(AA_kinase)
PF01472
(PUA) 		3 GLU A  48
ASP A 167
ASP A 367
 None
 0.76A 3jb2A-4q1tA:
3.0		 3jb2A-4q1tA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4y COXSACKIEVIRUS
CAPSID PROTEIN VP1
COXSACKIEVIRUS
CAPSID PROTEIN VP3

(Enterovirus C;
Enterovirus C) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 GLU 1  78
ASP 3  18
ASP 1 133
 None
 0.70A 3jb2A-4q4y1:
undetectable		 3jb2A-4q4y1:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzp ENGINEERED PROTEIN
OR366

(synthetic
construct) 		PF00514
(Arm)
PF13646
(HEAT_2) 		3 GLU A  77
ASP A  42
ASP A  84
 None
 0.76A 3jb2A-4rzpA:
2.0		 3jb2A-4rzpA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uzu ALPHA-AMYLASE

(Geobacillus
stearothermophilus) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		3 GLU A 262
ASP A 101
ASP A 105
 NA  A1490 (-2.7A)
None
CA  A1484 (-3.2A)
 0.75A 3jb2A-4uzuA:
undetectable		 3jb2A-4uzuA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bnn CAPSID PROTEIN VP1
CAPSID PROTEIN VP3

(Enterovirus D;
Enterovirus D) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 GLU A  60
ASP C  18
ASP A 116
 None
 0.63A 3jb2A-5bnnA:
undetectable		 3jb2A-5bnnA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c0p ENDO-ARABINASE

(Bacteroides
thetaiotaomicron) 		PF04616
(Glyco_hydro_43) 		3 GLU A 179
ASP A 230
ASP A 104
 None
TRS  A 409 (-3.3A)
None
 0.76A 3jb2A-5c0pA:
undetectable		 3jb2A-5c0pA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5b DCC-INTERACTING
PROTEIN 13-ALPHA
DCC-INTERACTING
PROTEIN 13-BETA

(Homo sapiens;
Homo sapiens) 		PF00169
(PH)
PF16746
(BAR_3)
PF00169
(PH)
PF16746
(BAR_3) 		3 GLU A 155
ASP A 157
ASP B 265
 None
 0.62A 3jb2A-5c5bA:
undetectable		 3jb2A-5c5bA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c5s UNCONVENTIONAL
MYOSIN-IXB

(Homo sapiens) 		PF00620
(RhoGAP) 		3 GLU A 235
ASP A 122
ASP A 127
 None
 0.60A 3jb2A-5c5sA:
undetectable		 3jb2A-5c5sA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5czz CRISPR-ASSOCIATED
ENDONUCLEASE CAS9

(Staphylococcus
aureus) 		PF13395
(HNH_4)
PF16592
(Cas9_REC) 		3 GLU A 729
ASP A 712
ASP A 722
 None
 0.73A 3jb2A-5czzA:
2.3		 3jb2A-5czzA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fcl CRISPR-ASSOCIATED
ENDONUCLEASE CAS1

(Pectobacterium
atrosepticum) 		PF01867
(Cas_Cas1) 		3 GLU A 191
ASP A 273
ASP A 266
 None
 0.70A 3jb2A-5fclA:
undetectable		 3jb2A-5fclA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fhc ANTIBODY 114 FAB
HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 GLU H  46
ASP H  42
ASP H  86
 None
 0.76A 3jb2A-5fhcH:
undetectable		 3jb2A-5fhcH:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fq2 SUMO-ACTIVATING
ENZYME SUBUNIT 2

(Homo sapiens) 		PF14732
(UAE_UbL) 		3 GLU B 545
ASP B 541
ASP B 537
 None
 0.61A 3jb2A-5fq2B:
undetectable		 3jb2A-5fq2B:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gai PORTAL PROTEIN

(Salmonella
virus P22) 		PF16510
(P22_portal) 		3 GLU A 503
ASP A 237
ASP A 509
 None
 0.71A 3jb2A-5gaiA:
undetectable		 3jb2A-5gaiA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h11 UNCHARACTERIZED
PROTEIN

(Danio rerio) 		PF07393
(Sec10) 		3 GLU A 347
ASP A 351
ASP A 438
 None
 0.51A 3jb2A-5h11A:
2.1		 3jb2A-5h11A:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN

(Lachnoclostridium
phytofermentans) 		PF17167
(Glyco_hydro_36) 		3 GLU A 662
ASP A 713
ASP A 719
 None
 0.65A 3jb2A-5h42A:
undetectable		 3jb2A-5h42A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hu3 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II ALPHA
CHAIN

(Drosophila
melanogaster) 		PF00069
(Pkinase) 		3 GLU A 237
ASP A 239
ASP A 232
 None
 0.52A 3jb2A-5hu3A:
undetectable		 3jb2A-5hu3A:
13.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ig1 CAMK/CAMK2 PROTEIN
KINASE

(Salpingoeca
rosetta) 		PF00069
(Pkinase) 		3 GLU A 240
ASP A 242
ASP A 235
 None
 0.53A 3jb2A-5ig1A:
undetectable		 3jb2A-5ig1A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxr CHROMATIN-REMODELING
COMPLEX ATPASE-LIKE
PROTEIN

(Thermothelomyces
thermophila) 		PF00176
(SNF2_N)
PF00271
(Helicase_C) 		3 GLU A 474
ASP A 482
ASP A 524
 None
 0.67A 3jb2A-5jxrA:
undetectable		 3jb2A-5jxrA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5liv CYTOCHROME P450
CYP260A1,CYTOCHROME
P450 CYP260A1

(Sorangium
cellulosum) 		PF00067
(p450) 		3 GLU A 223
ASP A 217
ASP A 430
 None
 0.70A 3jb2A-5livA:
undetectable		 3jb2A-5livA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpd 26S PROTEASOME
REGULATORY SUBUNIT
RPN7
26S PROTEASOME
REGULATORY SUBUNIT
RPN3

(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		PF01399
(PCI)
PF10602
(RPN7)
PF01399
(PCI)
PF08375
(Rpn3_C) 		3 GLU S 444
ASP R 382
ASP S 440
 None
 0.77A 3jb2A-5mpdS:
2.2		 3jb2A-5mpdS:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msc CARBOXYLIC ACID
REDUCTASE

(Nocardia
iowensis) 		PF00501
(AMP-binding) 		3 GLU A 187
ASP A 116
ASP A 107
 None
 0.76A 3jb2A-5mscA:
2.1		 3jb2A-5mscA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE

(Mus musculus) 		PF06090
(Ins_P5_2-kin) 		3 GLU A 365
ASP A  65
ASP A  57
 None
 0.62A 3jb2A-5mwlA:
undetectable		 3jb2A-5mwlA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o7j HISTIDINE KINASE

(Pseudomonas
aeruginosa) 		no annotation 3 GLU A 145
ASP A  65
ASP A 143
 None
 0.77A 3jb2A-5o7jA:
undetectable		 3jb2A-5o7jA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5osn CAPSID PROTEIN
CAPSID PROTEIN

(Enterovirus E;
Enterovirus E) 		PF00073
(Rhv)
PF00073
(Rhv) 		3 GLU A  67
ASP C  18
ASP A 111
 None
 0.55A 3jb2A-5osnA:
undetectable		 3jb2A-5osnA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7s GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE

(Paenibacillus
sp. 598K) 		PF01055
(Glyco_hydro_31)
PF16338
(DUF4968)
PF16990
(CBM_35)
PF17137
(DUF5110) 		3 GLU A 292
ASP A 334
ASP A 287
 None
 0.77A 3jb2A-5x7sA:
undetectable		 3jb2A-5x7sA:
21.80