SIMILAR PATTERNS OF AMINO ACIDS FOR 3IT4_B_ACTB601

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lcm TRANSESTERASE

(Aspergillus
terreus) 		PF00144
(Beta-lactamase) 		4 ASN A 316
ARG A 337
LEU A 347
MET A 331
 None
 1.42A 3it4B-4lcmA:
0.0
3it4C-4lcmA:
0.0		 3it4B-4lcmA:
22.30
3it4C-4lcmA:
20.44