SIMILAR PATTERNS OF AMINO ACIDS FOR 3ILT_B_TRUB800
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dmu | BGLI RESTRICTIONENDONUCLEASE (Bacillussubtilis) |
PF14562(Endonuc_BglI) | 5 | PRO A 290LEU A 285SER A 239LEU A 35ILE A 288 | None | 1.35A | 3iltB-1dmuA:undetectable3iltE-1dmuA:undetectable | 3iltB-1dmuA:22.443iltE-1dmuA:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kcx | DIHYDROPYRIMIDINASERELATED PROTEIN-1 (Mus musculus) |
PF01979(Amidohydro_1) | 5 | SER A 114LEU A 152LEU A 117ILE A 141SER A 119 | None | 1.26A | 3iltB-1kcxA:undetectable3iltE-1kcxA:undetectable | 3iltB-1kcxA:20.003iltE-1kcxA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lsn | RNASE H (Simian foamyvirus) |
PF00075(RNase_H) | 5 | LEU A 95LEU A 111ILE A 120SER A 115LYS A 118 | None | 1.34A | 3iltB-2lsnA:undetectable3iltE-2lsnA:undetectable | 3iltB-2lsnA:22.053iltE-2lsnA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vn7 | GLUCOAMYLASE (Trichodermareesei) |
PF00686(CBM_20)PF00723(Glyco_hydro_15) | 5 | LEU A 135SER A 139LEU A 142ILE A 158SER A 152 | None | 1.11A | 3iltB-2vn7A:undetectable3iltE-2vn7A:undetectable | 3iltB-2vn7A:17.723iltE-2vn7A:17.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zns | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 1 (Homo sapiens) |
PF10613(Lig_chan-Glu_bd) | 6 | LYS A 516PRO A 517MET A 519LEU A 768LEU A 776LYS A 780 | None | 0.90A | 3iltB-2znsA:35.43iltE-2znsA:35.4 | 3iltB-2znsA:51.923iltE-2znsA:51.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eo3 | BIFUNCTIONALUDP-N-ACETYLGLUCOSAMINE2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE (Homo sapiens) |
PF00480(ROK) | 5 | LYS A 433LEU A 706LEU A 410ILE A 430SER A 408 | None | 1.45A | 3iltB-3eo3A:undetectable3iltE-3eo3A:undetectable | 3iltB-3eo3A:19.723iltE-3eo3A:19.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3h6t | GLUTAMATE RECEPTOR 2 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 8 | LYS A 104PRO A 105MET A 107SER A 108LEU A 239SER A 242LEU A 247LYS A 251 | NoneCYZ A 265 (-3.9A)NoneCYZ A 265 (-2.8A)CYZ A 265 (-4.7A)CYZ A 265 (-2.9A)CYZ A 265 (-4.3A)CYZ A 265 ( 4.4A) | 0.57A | 3iltB-3h6tA:37.53iltE-3h6tA:37.0 | 3iltB-3h6tA:100.003iltE-3h6tA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3otx | ADENOSINE KINASE,PUTATIVE (Trypanosomabrucei) |
PF00294(PfkB) | 5 | SER A 197LEU A 213LEU A 171ILE A 219SER A 167 | None | 1.33A | 3iltB-3otxA:undetectable3iltE-3otxA:undetectable | 3iltB-3otxA:20.343iltE-3otxA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q98 | TRANSCARBAMYLASE (Escherichiacoli) |
PF00185(OTCace)PF02729(OTCace_N) | 5 | LEU A 15SER A 17LEU A 19ILE A 12LYS A 379 | None | 1.45A | 3iltB-3q98A:undetectable3iltE-3q98A:undetectable | 3iltB-3q98A:22.473iltE-3q98A:22.47 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxm | GLUTAMATE RECEPTORIONOTROPIC, KAINATE2 (Homo sapiens) |
PF10613(Lig_chan-Glu_bd) | 5 | LYS A 500MET A 503LEU A 752LEU A 760LYS A 764 | None | 0.86A | 3iltB-3qxmA:34.83iltE-3qxmA:34.8 | 3iltB-3qxmA:51.923iltE-3qxmA:51.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxm | GLUTAMATE RECEPTORIONOTROPIC, KAINATE2 (Homo sapiens) |
PF10613(Lig_chan-Glu_bd) | 5 | LYS A 500PRO A 501MET A 503LEU A 752LEU A 760 | None | 0.75A | 3iltB-3qxmA:34.83iltE-3qxmA:34.8 | 3iltB-3qxmA:51.923iltE-3qxmA:51.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3u92 | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 3 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 6 | LYS A 103PRO A 104MET A 106LEU A 234LEU A 242LYS A 246 | NoneNoneNoneNoneNone ZN A 259 (-3.5A) | 0.94A | 3iltB-3u92A:34.33iltE-3u92A:33.8 | 3iltB-3u92A:51.343iltE-3u92A:51.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gwn | MEPRIN A SUBUNITBETA (Homo sapiens) |
PF00629(MAM)PF01400(Astacin) | 5 | SER A 316LEU A 345SER A 416ILE A 380SER A 348 | None | 1.39A | 3iltB-4gwnA:undetectable3iltE-4gwnA:undetectable | 3iltB-4gwnA:19.493iltE-4gwnA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ha6 | PYRIDOXINE 4-OXIDASE (Mesorhizobiumloti) |
PF00732(GMC_oxred_N)PF05199(GMC_oxred_C) | 5 | PRO A 463LEU A 500LEU A 305ILE A 505SER A 495 | NoneNoneNoneFAD A 601 (-4.4A)None | 1.45A | 3iltB-4ha6A:undetectable3iltE-4ha6A:undetectable | 3iltB-4ha6A:17.193iltE-4ha6A:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ii3 | UBIQUITIN-60SRIBOSOMAL PROTEINL40 (Schizosaccharomycespombe) |
PF00240(ubiquitin) | 5 | LEU B 69LEU B 15ILE B 36SER B 28LYS B 27 | None | 1.50A | 3iltB-4ii3B:undetectable3iltE-4ii3B:undetectable | 3iltB-4ii3B:20.663iltE-4ii3B:20.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rxm | POSSIBLE SUGAR ABCSUPERFAMILY ATPBINDING CASSETTETRANSPORTER, BINDINGPROTEIN (Mannheimiahaemolytica) |
PF13407(Peripla_BP_4) | 5 | PRO A 32SER A 64LEU A 42LEU A 34SER A 36 | NoneNoneNoneNoneINS A 401 ( 4.4A) | 1.36A | 3iltB-4rxmA:2.13iltE-4rxmA:3.4 | 3iltB-4rxmA:21.813iltE-4rxmA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ux3 | MITOTIC CHROMOSOMEDETERMINANT-RELATEDPROTEINSTRUCTURALMAINTENANCE OFCHROMOSOMES PROTEIN3 (Saccharomycescerevisiae) |
PF02463(SMC_N)PF04825(Rad21_Rec8_N) | 5 | LYS A1034SER B 54LEU A 179LEU B 68ILE A1030 | None | 1.03A | 3iltB-4ux3A:undetectable3iltE-4ux3A:undetectable | 3iltB-4ux3A:19.143iltE-4ux3A:19.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4wxj | GLUTAMATE RECEPTORIIB,GLUTAMATERECEPTOR IIB (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 5 | PRO A 112MET A 114LEU A 245SER A 248LEU A 253 | None | 0.62A | 3iltB-4wxjA:34.63iltE-4wxjA:34.3 | 3iltB-4wxjA:41.423iltE-4wxjA:41.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d6g | 50S RIBOSOMALPROTEIN L10 (Methanocaldococcusjannaschii) |
PF00466(Ribosomal_L10) | 5 | PRO A 137MET A 135LEU A 141ILE A 153SER A 132 | None | 1.27A | 3iltB-5d6gA:undetectable3iltE-5d6gA:undetectable | 3iltB-5d6gA:25.443iltE-5d6gA:25.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dtb | CG3822 (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 5 | PRO A 109MET A 111LEU A 242LEU A 250LYS A 254 | None | 0.66A | 3iltB-5dtbA:35.83iltE-5dtbA:35.7 | 3iltB-5dtbA:54.793iltE-5dtbA:54.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ict | GLUTAMATE RECEPTOR 1 (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 5 | LYS A 110PRO A 111MET A 113LEU A 244LEU A 252 | None | 0.98A | 3iltB-5ictA:35.93iltE-5ictA:35.6 | 3iltB-5ictA:55.813iltE-5ictA:55.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ikb | GLUTAMATE RECEPTORIONOTROPIC, KAINATE4,GLUTAMATE RECEPTORIONOTROPIC, KAINATE4 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 5 | LYS A 103PRO A 104MET A 106LEU A 235LEU A 243 | None | 0.94A | 3iltB-5ikbA:32.63iltE-5ikbA:32.2 | 3iltB-5ikbA:54.413iltE-5ikbA:54.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ikb | GLUTAMATE RECEPTORIONOTROPIC, KAINATE4,GLUTAMATE RECEPTORIONOTROPIC, KAINATE4 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 5 | LYS A 103PRO A 104MET A 106LEU A 243LYS A 247 | None | 0.96A | 3iltB-5ikbA:32.63iltE-5ikbA:32.2 | 3iltB-5ikbA:54.413iltE-5ikbA:54.41 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l1b | GLUTAMATE RECEPTOR2,GLUTAMATE RECEPTOR2 (Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 8 | LYS A 493PRO A 494MET A 496SER A 497LEU A 751SER A 754LEU A 759LYS A 763 | None | 0.56A | 3iltB-5l1bA:19.53iltE-5l1bA:19.1 | 3iltB-5l1bA:70.443iltE-5l1bA:70.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wel | CHIMERA OF GLUTAMATERECEPTOR 2, GERMCELL-SPECIFIC GENE1-LIKE PROTEIN (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF07803(GSG-1)PF10613(Lig_chan-Glu_bd) | 8 | LYS A 493PRO A 494MET A 496SER A 497LEU A 751SER A 754LEU A 759LYS A 763 | None | 0.99A | 3iltB-5welA:29.33iltE-5welA:28.8 | 3iltB-5welA:66.933iltE-5welA:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5weo | GLUTAMATE RECEPTOR2,VOLTAGE-DEPENDENTCALCIUM CHANNELGAMMA-2 SUBUNITCHIMERA (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF00822(PMP22_Claudin)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 6 | LYS A 493MET A 496LEU A 751SER A 754LEU A 759LYS A 763 | NoneCYZ A1302 (-4.3A)NoneCYZ A1302 ( 4.1A)NoneCYZ A1302 (-2.9A) | 0.96A | 3iltB-5weoA:21.43iltE-5weoA:21.3 | 3iltB-5weoA:66.933iltE-5weoA:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5weo | GLUTAMATE RECEPTOR2,VOLTAGE-DEPENDENTCALCIUM CHANNELGAMMA-2 SUBUNITCHIMERA (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF00822(PMP22_Claudin)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 6 | LYS A 493MET A 496SER A 497LEU A 751LEU A 759LYS A 763 | NoneCYZ A1302 (-4.3A)CYZ A1302 (-3.2A)NoneNoneCYZ A1302 (-2.9A) | 1.02A | 3iltB-5weoA:21.43iltE-5weoA:21.3 | 3iltB-5weoA:66.933iltE-5weoA:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5weo | GLUTAMATE RECEPTOR2,VOLTAGE-DEPENDENTCALCIUM CHANNELGAMMA-2 SUBUNITCHIMERA (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF00822(PMP22_Claudin)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 5 | LYS A 493PRO A 494MET A 496LEU A 751SER A 754 | NoneCYZ A1302 (-4.5A)CYZ A1302 (-4.3A)NoneCYZ A1302 ( 4.1A) | 0.97A | 3iltB-5weoA:21.43iltE-5weoA:21.3 | 3iltB-5weoA:66.933iltE-5weoA:66.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5weo | GLUTAMATE RECEPTOR2,VOLTAGE-DEPENDENTCALCIUM CHANNELGAMMA-2 SUBUNITCHIMERA (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF00822(PMP22_Claudin)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 5 | LYS A 493PRO A 494MET A 496SER A 497LEU A 751 | NoneCYZ A1302 (-4.5A)CYZ A1302 (-4.3A)CYZ A1302 (-3.2A)None | 0.81A | 3iltB-5weoA:21.43iltE-5weoA:21.3 | 3iltB-5weoA:66.933iltE-5weoA:66.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y0q | UPF0348 PROTEINB4417_3650 (Bacillussubtilis) |
no annotation | 5 | PRO A 358SER A 365LEU A 355ILE A 335SER A 361 | None | 1.48A | 3iltB-5y0qA:undetectable3iltE-5y0qA:undetectable | 3iltB-5y0qA:undetectable3iltE-5y0qA:undetectable |