SIMILAR PATTERNS OF AMINO ACIDS FOR 3IAK_A_EV1A415_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1soj CGMP-INHIBITED
3',5'-CYCLIC
PHOSPHODIESTERASE B

(Homo sapiens) 		PF00233
(PDEase_I) 		6 TYR A 736
ILE A 955
PHE A 959
GLN A 988
PHE A 991
ILE A 995
 IBM  A2111 (-4.5A)
IBM  A2111 (-4.2A)
None
IBM  A2111 (-3.3A)
IBM  A2111 (-3.6A)
None
 0.58A 3iakA-1sojA:
42.0		 3iakA-1sojA:
31.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zkl HIGH-AFFINITY
CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 7A

(Homo sapiens) 		PF00233
(PDEase_I) 		5 TYR A 211
ASN A 365
PHE A 384
GLN A 413
PHE A 416
 IBM  A 503 (-4.6A)
IBM  A 503 ( 4.7A)
IBM  A 503 (-4.5A)
IBM  A 503 (-3.0A)
IBM  A 503 (-3.4A)
 0.53A 3iakA-1zklA:
44.9		 3iakA-1zklA:
33.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qyk CYCLIC AMP-SPECIFIC
PHOSPHODIESTERASE
HSPDE4A10

(Homo sapiens) 		PF00233
(PDEase_I) 		8 TYR A 371
ASN A 533
ILE A 548
PHE A 552
MET A 569
GLN A 581
PHE A 584
ILE A 588
 NPV  A   3 (-4.4A)
NPV  A   3 (-4.4A)
NPV  A   3 (-3.8A)
NPV  A   3 (-4.8A)
NPV  A   3 (-3.1A)
NPV  A   3 (-3.1A)
NPV  A   3 (-3.3A)
None
 0.34A 3iakA-2qykA:
51.7		 3iakA-2qykA:
82.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qyk CYCLIC AMP-SPECIFIC
PHOSPHODIESTERASE
HSPDE4A10

(Homo sapiens) 		PF00233
(PDEase_I) 		8 TYR A 371
MET A 485
ASN A 533
ILE A 548
PHE A 552
MET A 569
GLN A 581
PHE A 584
 NPV  A   3 (-4.4A)
None
NPV  A   3 (-4.4A)
NPV  A   3 (-3.8A)
NPV  A   3 (-4.8A)
NPV  A   3 (-3.1A)
NPV  A   3 (-3.1A)
NPV  A   3 (-3.3A)
 0.59A 3iakA-2qykA:
51.7		 3iakA-2qykA:
82.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qym PHOSPHODIESTERASE 4C

(Homo sapiens) 		PF00233
(PDEase_I) 		5 TYR A 281
ASN A 443
ILE A 458
PHE A 494
ILE A 498
 None
 0.65A 3iakA-2qymA:
43.1		 3iakA-2qymA:
82.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qym PHOSPHODIESTERASE 4C

(Homo sapiens) 		PF00233
(PDEase_I) 		5 TYR A 281
MET A 395
ASN A 443
ILE A 458
PHE A 494
 None
 0.67A 3iakA-2qymA:
43.1		 3iakA-2qymA:
82.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r8q CLASS I
PHOSPHODIESTERASE
PDEB1

(Leishmania
major) 		PF00233
(PDEase_I) 		6 TYR A 680
MET A 797
ASN A 838
PHE A 857
GLN A 887
PHE A 890
 IBM  A   3 ( 4.7A)
None
IBM  A   3 (-4.5A)
IBM  A   3 (-4.9A)
IBM  A   3 (-3.3A)
IBM  A   3 (-3.6A)
 0.74A 3iakA-2r8qA:
38.9		 3iakA-2r8qA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r8q CLASS I
PHOSPHODIESTERASE
PDEB1

(Leishmania
major) 		PF00233
(PDEase_I) 		6 TYR A 680
MET A 797
ASN A 838
PHE A 857
MET A 874
PHE A 890
 IBM  A   3 ( 4.7A)
None
IBM  A   3 (-4.5A)
IBM  A   3 (-4.9A)
IBM  A   3 ( 3.8A)
IBM  A   3 (-3.6A)
 0.85A 3iakA-2r8qA:
38.9		 3iakA-2r8qA:
30.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3b2r CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		5 TYR A 612
PHE A 786
GLN A 817
PHE A 820
ILE A 824
 VDN  A   1 (-4.8A)
None
VDN  A   1 (-3.0A)
VDN  A   1 (-3.6A)
None
 0.40A 3iakA-3b2rA:
30.8		 3iakA-3b2rA:
31.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjc CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		5 TYR A 612
PHE A 786
GLN A 817
PHE A 820
ILE A 824
 None
WAN  A 901 (-4.8A)
WAN  A 901 (-3.1A)
WAN  A 901 (-3.7A)
None
 0.42A 3iakA-3bjcA:
33.5		 3iakA-3bjcA:
17.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ecn HIGH AFFINITY
CAMP-SPECIFIC AND
IBMX-INSENSITIVE
3',5'-CYCLIC
PHOSPHODIESTERASE 8A

(Homo sapiens) 		PF00233
(PDEase_I) 		5 TYR A 555
ILE A 744
GLN A 778
PHE A 781
ILE A 786
 None
IBM  A   3 (-4.3A)
IBM  A   3 (-3.4A)
IBM  A   3 (-3.5A)
None
 1.45A 3iakA-3ecnA:
43.0		 3iakA-3ecnA:
33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ecn HIGH AFFINITY
CAMP-SPECIFIC AND
IBMX-INSENSITIVE
3',5'-CYCLIC
PHOSPHODIESTERASE 8A

(Homo sapiens) 		PF00233
(PDEase_I) 		6 TYR A 555
MET A 670
ASN A 729
ILE A 744
GLN A 778
PHE A 781
 None
IBM  A   3 (-4.5A)
None
IBM  A   3 (-4.3A)
IBM  A   3 (-3.4A)
IBM  A   3 (-3.5A)
 0.53A 3iakA-3ecnA:
43.0		 3iakA-3ecnA:
33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g4g CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		PF00233
(PDEase_I) 		8 TYR A 325
MET A 439
ASN A 487
ILE A 502
PHE A 506
GLN A 535
PHE A 538
ILE A 542
 None
D71  A 901 ( 4.0A)
D71  A 901 (-4.5A)
D71  A 901 (-4.1A)
D71  A 901 (-4.8A)
D71  A 901 (-3.1A)
D71  A 901 (-3.9A)
None
 0.44A 3iakA-3g4gA:
52.1		 3iakA-3g4gA:
81.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i1l HEMAGGLUTININ-ESTERA
SE PROTEIN

(Porcine
torovirus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		5 TYR A 238
PHE A 237
MET A 259
PHE A 211
ILE A 274
 None
 1.49A 3iakA-3i1lA:
undetectable		 3iakA-3i1lA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i5g MYOSIN HEAVY CHAIN
ISOFORM A

(Doryteuthis
pealeii) 		PF00063
(Myosin_head)
PF00612
(IQ)
PF02736
(Myosin_N) 		5 MET A  88
ASN A 696
MET A 495
GLN A 488
ILE A 702
 None
 1.17A 3iakA-3i5gA:
undetectable		 3iakA-3i5gA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ibj CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I)
PF01590
(GAF)
PF13185
(GAF_2) 		5 TYR A 655
ILE A 826
GLN A 859
PHE A 862
ILE A 866
 None
 0.68A 3iakA-3ibjA:
32.0		 3iakA-3ibjA:
18.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o57 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		5 ILE A 410
MET A 431
GLN A 443
PHE A 446
ILE A 450
 ZG2  A 506 (-4.4A)
ZG2  A 506 (-3.4A)
ZG2  A 506 (-3.3A)
ZG2  A 506 (-3.6A)
None
 0.81A 3iakA-3o57A:
51.2		 3iakA-3o57A:
82.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o57 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		5 MET A 347
ILE A 410
MET A 431
GLN A 443
PHE A 446
 ZG2  A 506 (-3.9A)
ZG2  A 506 (-4.4A)
ZG2  A 506 (-3.4A)
ZG2  A 506 (-3.3A)
ZG2  A 506 (-3.6A)
 0.95A 3iakA-3o57A:
51.2		 3iakA-3o57A:
82.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o57 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		7 TYR A 233
ASN A 395
ILE A 410
PHE A 414
GLN A 443
PHE A 446
ILE A 450
 None
ZG2  A 506 (-4.3A)
ZG2  A 506 (-4.4A)
ZG2  A 506 (-4.4A)
ZG2  A 506 (-3.3A)
ZG2  A 506 (-3.6A)
None
 0.52A 3iakA-3o57A:
51.2		 3iakA-3o57A:
82.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o57 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		7 TYR A 233
MET A 347
ASN A 395
ILE A 410
PHE A 414
GLN A 443
PHE A 446
 None
ZG2  A 506 (-3.9A)
ZG2  A 506 (-4.3A)
ZG2  A 506 (-4.4A)
ZG2  A 506 (-4.4A)
ZG2  A 506 (-3.3A)
ZG2  A 506 (-3.6A)
 0.77A 3iakA-3o57A:
51.2		 3iakA-3o57A:
82.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3sl5 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		PF00233
(PDEase_I) 		8 TYR A 159
ASN A 321
ILE A 336
PHE A 340
MET A 357
GLN A 369
PHE A 372
ILE A 376
 TYR  A 159 (-1.3A)
ASN  A 321 (-0.6A)
ILE  A 336 ( 0.4A)
PHE  A 340 (-1.3A)
MET  A 357 (-0.0A)
GLN  A 369 (-0.6A)
PHE  A 372 (-1.3A)
ILE  A 376 (-0.6A)
 0.53A 3iakA-3sl5A:
51.9		 3iakA-3sl5A:
94.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3sl5 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		PF00233
(PDEase_I) 		8 TYR A 159
MET A 273
ASN A 321
ILE A 336
PHE A 340
MET A 357
GLN A 369
PHE A 372
 TYR  A 159 (-1.3A)
MET  A 273 (-0.0A)
ASN  A 321 (-0.6A)
ILE  A 336 ( 0.4A)
PHE  A 340 (-1.3A)
MET  A 357 (-0.0A)
GLN  A 369 (-0.6A)
PHE  A 372 (-1.3A)
 0.73A 3iakA-3sl5A:
51.9		 3iakA-3sl5A:
94.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ui7 CAMP AND
CAMP-INHIBITED CGMP
3',5'-CYCLIC
PHOSPHODIESTERASE
10A

(Homo sapiens) 		PF00233
(PDEase_I) 		5 TYR A 524
ILE A 692
MET A 713
GLN A 726
PHE A 729
 C1L  A   1 ( 4.8A)
C1L  A   1 (-4.3A)
C1L  A   1 (-3.7A)
C1L  A   1 (-2.9A)
C1L  A   1 (-3.5A)
 1.16A 3iakA-3ui7A:
37.8		 3iakA-3ui7A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ui7 CAMP AND
CAMP-INHIBITED CGMP
3',5'-CYCLIC
PHOSPHODIESTERASE
10A

(Homo sapiens) 		PF00233
(PDEase_I) 		5 TYR A 524
ILE A 692
PHE A 696
GLN A 726
PHE A 729
 C1L  A   1 ( 4.8A)
C1L  A   1 (-4.3A)
C1L  A   1 ( 4.7A)
C1L  A   1 (-2.9A)
C1L  A   1 (-3.5A)
 0.74A 3iakA-3ui7A:
37.8		 3iakA-3ui7A:
28.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v94 CYCLIC NUCLEOTIDE
SPECIFIC
PHOSPHODIESTERASE

(Trypanosoma
cruzi) 		PF00233
(PDEase_I) 		6 TYR A 367
MET A 482
ILE A 538
PHE A 542
GLN A 570
PHE A 573
 WYQ  A 701 (-4.5A)
WYQ  A 701 (-4.5A)
WYQ  A 701 ( 4.1A)
WYQ  A 701 (-4.7A)
WYQ  A 701 (-3.3A)
WYQ  A 701 (-3.4A)
 0.52A 3iakA-3v94A:
39.9		 3iakA-3v94A:
30.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htz CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		6 TYR A 655
ILE A 826
PHE A 830
GLN A 859
PHE A 862
ILE A 866
 None
 0.43A 3iakA-4htzA:
38.1		 3iakA-4htzA:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htz CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		6 TYR A 655
ILE A 826
PHE A 830
MET A 847
PHE A 862
ILE A 866
 None
 0.85A 3iakA-4htzA:
38.1		 3iakA-4htzA:
28.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i15 CLASS 1
PHOSPHODIESTERASE
PDEB1

(Trypanosoma
brucei) 		PF00233
(PDEase_I) 		6 TYR A 668
MET A 785
ASN A 825
PHE A 844
GLN A 874
PHE A 877
 None
 0.84A 3iakA-4i15A:
38.1		 3iakA-4i15A:
32.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4i15 CLASS 1
PHOSPHODIESTERASE
PDEB1

(Trypanosoma
brucei) 		PF00233
(PDEase_I) 		6 TYR A 668
MET A 785
ASN A 825
PHE A 844
MET A 861
PHE A 877
 None
 0.88A 3iakA-4i15A:
38.1		 3iakA-4i15A:
32.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wzi CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		8 TYR A 405
MET A 519
ASN A 567
ILE A 582
PHE A 586
GLN A 615
PHE A 618
ILE A 622
 None
 0.56A 3iakA-4wziA:
51.6		 3iakA-4wziA:
48.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5b25 CALCIUM/CALMODULIN-D
EPENDENT
3',5'-CYCLIC
NUCLEOTIDE
PHOSPHODIESTERASE 1B

(Homo sapiens) 		PF00233
(PDEase_I) 		6 TYR A 222
MET A 336
PHE A 392
GLN A 421
PHE A 424
ILE A 428
 None
4QJ  A 603 ( 3.9A)
GOL  A 607 (-3.9A)
4QJ  A 603 (-3.0A)
4QJ  A 603 (-3.5A)
None
 0.75A 3iakA-5b25A:
43.5		 3iakA-5b25A:
38.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h2r PHOSPHODIESTERASE

(Trypanosoma
brucei) 		no annotation 6 TYR A 668
MET A 785
ASN A 826
PHE A 845
GLN A 875
PHE A 878
 LLN  A1003 ( 4.8A)
LLN  A1003 (-4.0A)
LLN  A1003 (-4.4A)
LLN  A1003 (-4.6A)
LLN  A1003 (-3.0A)
LLN  A1003 (-3.8A)
 0.63A 3iakA-5h2rA:
38.8		 3iakA-5h2rA:
32.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5h2r PHOSPHODIESTERASE

(Trypanosoma
brucei) 		no annotation 6 TYR A 668
MET A 785
ASN A 826
PHE A 845
MET A 862
PHE A 878
 LLN  A1003 ( 4.8A)
LLN  A1003 (-4.0A)
LLN  A1003 (-4.4A)
LLN  A1003 (-4.6A)
LLN  A1003 (-3.5A)
LLN  A1003 (-3.8A)
 0.82A 3iakA-5h2rA:
38.8		 3iakA-5h2rA:
32.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohj CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		no annotation 7 MET A 519
ASN A 567
ILE A 582
PHE A 586
MET A 603
GLN A 615
PHE A 618
 9VE  A 801 (-3.8A)
9VE  A 801 (-4.1A)
9VE  A 801 (-4.1A)
9VE  A 801 (-3.6A)
9VE  A 801 (-3.6A)
9VE  A 801 (-3.2A)
9VE  A 801 (-3.9A)
 0.92A 3iakA-5ohjA:
51.5		 3iakA-5ohjA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ohj CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		no annotation 8 TYR A 405
ASN A 567
ILE A 582
PHE A 586
MET A 603
GLN A 615
PHE A 618
ILE A 622
 None
9VE  A 801 (-4.1A)
9VE  A 801 (-4.1A)
9VE  A 801 (-3.6A)
9VE  A 801 (-3.6A)
9VE  A 801 (-3.2A)
9VE  A 801 (-3.9A)
9VE  A 801 (-4.8A)
 0.63A 3iakA-5ohjA:
51.5		 3iakA-5ohjA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ubj ALPHA-L-ARABINOFURAN
OSIDASE AXHA-2

(Aspergillus
nidulans) 		PF03664
(Glyco_hydro_62) 		5 TYR A 126
MET A 184
ILE A 114
PHE A 105
ILE A 186
 None
 1.46A 3iakA-5ubjA:
undetectable		 3iakA-5ubjA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wh6 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		no annotation 8 TYR A 159
ASN A 321
ILE A 336
PHE A 340
MET A 357
GLN A 369
PHE A 372
ILE A 376
 AKJ  A 601 ( 4.7A)
AKJ  A 601 (-4.3A)
AKJ  A 601 (-3.8A)
AKJ  A 601 (-4.5A)
AKJ  A 601 (-3.4A)
AKJ  A 601 (-3.0A)
AKJ  A 601 (-4.1A)
None
 0.30A 3iakA-5wh6A:
53.2		 3iakA-5wh6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wh6 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		no annotation 8 TYR A 159
MET A 273
ASN A 321
ILE A 336
PHE A 340
MET A 357
GLN A 369
PHE A 372
 AKJ  A 601 ( 4.7A)
AKJ  A 601 ( 3.9A)
AKJ  A 601 (-4.3A)
AKJ  A 601 (-3.8A)
AKJ  A 601 (-4.5A)
AKJ  A 601 (-3.4A)
AKJ  A 601 (-3.0A)
AKJ  A 601 (-4.1A)
 0.52A 3iakA-5wh6A:
53.2		 3iakA-5wh6A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f1j -

(-) 		no annotation 5 TYR A 128
MET A 186
ILE A 116
PHE A 107
ILE A 188
 None
 1.46A 3iakA-6f1jA:
undetectable		 3iakA-6f1jA:
undetectable