SIMILAR PATTERNS OF AMINO ACIDS FOR 3HZN_G_ACTG225

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism
Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
12as ASPARAGINE
SYNTHETASE


(Escherichia
coli)
PF03590
(AsnA)
3 PRO A 159
LEU A 157
GLN A 306
None
0.69A 3hznG-12asA:
0.5
3hznH-12asA:
1.8
3hznG-12asA:
20.77
3hznH-12asA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a2o CHEB METHYLESTERASE

(Salmonella
enterica)
PF00072
(Response_reg)
PF01339
(CheB_methylest)
3 PRO A 179
LEU A 180
GLN A 208
None
0.67A 3hznG-1a2oA:
0.0
3hznH-1a2oA:
0.0
3hznG-1a2oA:
22.54
3hznH-1a2oA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a44 PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN


(Bos taurus)
PF01161
(PBP)
3 PRO A 129
LEU A 130
GLN A 126
None
0.54A 3hznG-1a44A:
0.0
3hznH-1a44A:
0.0
3hznG-1a44A:
20.61
3hznH-1a44A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ct9 ASPARAGINE
SYNTHETASE B


(Escherichia
coli)
PF00733
(Asn_synthase)
PF13537
(GATase_7)
3 PRO A  61
LEU A  62
GLN A  60
None
0.67A 3hznG-1ct9A:
0.0
3hznH-1ct9A:
0.0
3hznG-1ct9A:
17.63
3hznH-1ct9A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fiu TYPE II RESTRICTION
ENZYME NGOMI


(Neisseria
gonorrhoeae)
PF09015
(NgoMIV_restric)
3 PRO A 178
LEU A 179
GLN A 109
None
0.69A 3hznG-1fiuA:
0.6
3hznH-1fiuA:
0.0
3hznG-1fiuA:
20.34
3hznH-1fiuA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kn3 PHOSPHATIDYLETHANOLA
MINE BINDING
PROTEIN-2


(Mus musculus)
PF01161
(PBP)
3 PRO A 130
LEU A 131
GLN A 127
None
0.70A 3hznG-1kn3A:
0.0
3hznH-1kn3A:
0.0
3hznG-1kn3A:
18.83
3hznH-1kn3A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lth L-LACTATE
DEHYDROGENASE (T-
AND R- STATE
TETRAMER COMPLEX)


(Bifidobacterium
longum)
no annotation 3 PRO T 209
LEU T 210
GLN T 164
None
0.67A 3hznG-1lthT:
0.0
3hznH-1lthT:
0.0
3hznG-1lthT:
22.08
3hznH-1lthT:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1o5e SERINE PROTEASE
HEPSIN


(Homo sapiens)
PF09272
(Hepsin-SRCR)
3 PRO L   8
LEU L   6
GLN L  10
None
0.68A 3hznG-1o5eL:
0.0
3hznH-1o5eL:
0.0
3hznG-1o5eL:
21.70
3hznH-1o5eL:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oxx ABC TRANSPORTER, ATP
BINDING PROTEIN


(Sulfolobus
solfataricus)
PF00005
(ABC_tran)
3 PRO K 232
LEU K 228
GLN K 221
None
None
IOD  K1931 (-4.4A)
0.72A 3hznG-1oxxK:
0.0
3hznH-1oxxK:
0.0
3hznG-1oxxK:
22.32
3hznH-1oxxK:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1psw ADP-HEPTOSE LPS
HEPTOSYLTRANSFERASE
II


(Escherichia
coli)
PF01075
(Glyco_transf_9)
3 PRO A 154
LEU A 155
GLN A 153
None
0.61A 3hznG-1pswA:
undetectable
3hznH-1pswA:
undetectable
3hznG-1pswA:
19.03
3hznH-1pswA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pvd PYRUVATE
DECARBOXYLASE


(Saccharomyces
cerevisiae)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
3 PRO A 191
LEU A 189
GLN A 325
None
0.70A 3hznG-1pvdA:
undetectable
3hznH-1pvdA:
undetectable
3hznG-1pvdA:
16.64
3hznH-1pvdA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t5o TRANSLATION
INITIATION FACTOR
EIF2B, SUBUNIT DELTA


(Archaeoglobus
fulgidus)
PF01008
(IF-2B)
3 PRO A 299
LEU A 300
GLN A 296
None
0.43A 3hznG-1t5oA:
undetectable
3hznH-1t5oA:
undetectable
3hznG-1t5oA:
23.35
3hznH-1t5oA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tlq HYPOTHETICAL PROTEIN
YPJQ


(Bacillus
subtilis)
PF04608
(PgpA)
3 PRO A  45
LEU A  46
GLN A  34
None
0.65A 3hznG-1tlqA:
undetectable
3hznH-1tlqA:
undetectable
3hznG-1tlqA:
19.49
3hznH-1tlqA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM


(Streptococcus
mutans)
PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6)
3 PRO A1065
LEU A1066
GLN A1053
None
0.51A 3hznG-1wviA:
undetectable
3hznH-1wviA:
undetectable
3hznG-1wviA:
22.26
3hznH-1wviA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE


(Sulfurisphaera
tokodaii)
PF00294
(PfkB)
3 PRO A  21
LEU A  22
GLN A  93
None
0.69A 3hznG-1wyeA:
undetectable
3hznH-1wyeA:
undetectable
3hznG-1wyeA:
21.14
3hznH-1wyeA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b4v RNA EDITING COMPLEX
PROTEIN MP57


(Trypanosoma
brucei)
PF01909
(NTP_transf_2)
PF03828
(PAP_assoc)
3 PRO A 357
LEU A 358
GLN A  91
None
0.69A 3hznG-2b4vA:
undetectable
3hznH-2b4vA:
undetectable
3hznG-2b4vA:
19.02
3hznH-2b4vA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bjr MFP2B

(Ascaris suum)
PF12150
(MFP2b)
3 PRO A 226
LEU A 218
GLN A 228
None
0.50A 3hznG-2bjrA:
undetectable
3hznH-2bjrA:
undetectable
3hznG-2bjrA:
20.68
3hznH-2bjrA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c1d SOXA
SOXX


(Paracoccus
denitrificans;
Paracoccus
pantotrophus)
no annotation
PF00034
(Cytochrom_C)
3 PRO B 138
LEU B 136
GLN A 201
None
0.65A 3hznG-2c1dB:
undetectable
3hznH-2c1dB:
undetectable
3hznG-2c1dB:
22.81
3hznH-2c1dB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cpr EXOSOME COMPONENT 10

(Homo sapiens)
PF00570
(HRDC)
3 PRO A 580
LEU A 581
GLN A 505
None
0.58A 3hznG-2cprA:
undetectable
3hznH-2cprA:
undetectable
3hznG-2cprA:
18.35
3hznH-2cprA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2daq WHSC1L1 PROTEIN,
ISOFORM LONG


(Homo sapiens)
PF00855
(PWWP)
3 PRO A  36
LEU A  37
GLN A  40
None
0.68A 3hznG-2daqA:
undetectable
3hznH-2daqA:
undetectable
3hznG-2daqA:
19.91
3hznH-2daqA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fgo FERREDOXIN

(Pseudomonas
aeruginosa)
PF00037
(Fer4)
3 PRO A  59
LEU A   2
GLN A  50
None
SF4  A 202 (-4.3A)
None
0.70A 3hznG-2fgoA:
undetectable
3hznH-2fgoA:
undetectable
3hznG-2fgoA:
14.71
3hznH-2fgoA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hz7 GLUTAMINYL-TRNA
SYNTHETASE


(Deinococcus
radiodurans)
PF00749
(tRNA-synt_1c)
PF03950
(tRNA-synt_1c_C)
3 PRO A 332
LEU A  82
GLN A 337
None
0.73A 3hznG-2hz7A:
undetectable
3hznH-2hz7A:
undetectable
3hznG-2hz7A:
14.60
3hznH-2hz7A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ics ADENINE DEAMINASE

(Enterococcus
faecalis)
PF01979
(Amidohydro_1)
3 PRO A 184
LEU A 185
GLN A 177
None
0.73A 3hznG-2icsA:
undetectable
3hznH-2icsA:
undetectable
3hznG-2icsA:
19.05
3hznH-2icsA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iqx PHOSPHATIDYLETHANOLA
MINE-BINDING PROTEIN
1


(Rattus
norvegicus)
PF01161
(PBP)
3 PRO A 130
LEU A 131
GLN A 127
None
0.60A 3hznG-2iqxA:
undetectable
3hznH-2iqxA:
undetectable
3hznG-2iqxA:
23.63
3hznH-2iqxA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2krx ASL3597 PROTEIN

(Nostoc sp. PCC
7120)
PF12095
(CRR7)
3 PRO A  46
LEU A  47
GLN A  50
None
0.66A 3hznG-2krxA:
undetectable
3hznH-2krxA:
undetectable
3hznG-2krxA:
17.05
3hznH-2krxA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lul TYROSINE-PROTEIN
KINASE TEC


(Homo sapiens)
PF00169
(PH)
PF00779
(BTK)
3 PRO A  33
LEU A  34
GLN A  27
None
0.44A 3hznG-2lulA:
undetectable
3hznH-2lulA:
undetectable
3hznG-2lulA:
20.76
3hznH-2lulA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nxx ULTRASPIRACLE (USP,
NR2B4)


(Tribolium
castaneum)
PF00104
(Hormone_recep)
3 PRO A 239
LEU A 240
GLN A 243
None
0.70A 3hznG-2nxxA:
undetectable
3hznH-2nxxA:
undetectable
3hznG-2nxxA:
20.63
3hznH-2nxxA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o2k METHIONINE SYNTHASE

(Homo sapiens)
PF02965
(Met_synt_B12)
3 PRO A 931
LEU A 932
GLN A1068
None
0.51A 3hznG-2o2kA:
undetectable
3hznH-2o2kA:
3.3
3hznG-2o2kA:
21.73
3hznH-2o2kA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q5o PHENYLPYRUVATE
DECARBOXYLASE


(Azospirillum
brasilense)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
3 PRO A 373
LEU A 374
GLN A 371
None
0.70A 3hznG-2q5oA:
undetectable
3hznH-2q5oA:
undetectable
3hznG-2q5oA:
17.64
3hznH-2q5oA:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q60 RETINOID X RECEPTOR

(Polyandrocarpa
misakiensis)
PF00104
(Hormone_recep)
3 PRO A 168
LEU A 169
GLN A 172
None
0.70A 3hznG-2q60A:
undetectable
3hznH-2q60A:
undetectable
3hznG-2q60A:
21.77
3hznH-2q60A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r5s UNCHARACTERIZED
PROTEIN VP0806


(Vibrio
parahaemolyticus)
PF14559
(TPR_19)
PF14561
(TPR_20)
3 PRO A 175
LEU A 176
GLN A 179
None
0.65A 3hznG-2r5sA:
undetectable
3hznH-2r5sA:
undetectable
3hznG-2r5sA:
25.86
3hznH-2r5sA:
25.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vk4 PYRUVATE
DECARBOXYLASE


(Kluyveromyces
lactis)
PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N)
3 PRO A 191
LEU A 189
GLN A 325
None
0.61A 3hznG-2vk4A:
undetectable
3hznH-2vk4A:
0.2
3hznG-2vk4A:
18.15
3hznH-2vk4A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vut NITROGEN METABOLITE
REPRESSION REGULATOR
NMRA


(Aspergillus
nidulans)
PF05368
(NmrA)
3 PRO A  59
LEU A  60
GLN A  35
None
0.44A 3hznG-2vutA:
undetectable
3hznH-2vutA:
undetectable
3hznG-2vutA:
22.12
3hznH-2vutA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ww8 CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN


(Streptococcus
pneumoniae)
PF13519
(VWA_2)
3 PRO A 224
LEU A 225
GLN A 218
None
0.53A 3hznG-2ww8A:
undetectable
3hznH-2ww8A:
undetectable
3hznG-2ww8A:
12.88
3hznH-2ww8A:
12.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zba TRICHOTHECENE
3-O-ACETYLTRANSFERAS
E


(Fusarium
sporotrichioides)
PF02458
(Transferase)
3 PRO A 334
LEU A 335
GLN A 279
None
0.64A 3hznG-2zbaA:
undetectable
3hznH-2zbaA:
0.6
3hznG-2zbaA:
20.39
3hznH-2zbaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zpb NITRILE HYDRATASE
SUBUNIT BETA


(Rhodococcus
erythropolis)
PF02211
(NHase_beta)
3 PRO B 104
LEU B 105
GLN B  92
None
0.67A 3hznG-2zpbB:
undetectable
3hznH-2zpbB:
undetectable
3hznG-2zpbB:
23.51
3hznH-2zpbB:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cjx PROTEIN OF UNKNOWN
FUNCTION WITH A
CUPIN-LIKE FOLD


(Cupriavidus
pinatubonensis)
no annotation 3 PRO A  60
LEU A  61
GLN A 102
None
0.57A 3hznG-3cjxA:
undetectable
3hznH-3cjxA:
undetectable
3hznG-3cjxA:
17.89
3hznH-3cjxA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d2u UL18 PROTEIN

(Human
betaherpesvirus
5)
PF00129
(MHC_I)
PF07654
(C1-set)
3 PRO A 240
LEU A 241
GLN A 251
None
0.60A 3hznG-3d2uA:
undetectable
3hznH-3d2uA:
undetectable
3hznG-3d2uA:
17.87
3hznH-3d2uA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e59 PYOVERDINE
BIOSYNTHESIS PROTEIN
PVCA


(Pseudomonas
aeruginosa)
PF05141
(DIT1_PvcA)
3 PRO A 179
LEU A 180
GLN A 233
None
0.39A 3hznG-3e59A:
undetectable
3hznH-3e59A:
undetectable
3hznG-3e59A:
20.73
3hznH-3e59A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eo4 UNCHARACTERIZED
PROTEIN MJ1062


(Methanocaldococcus
jannaschii)
PF13302
(Acetyltransf_3)
3 PRO A 384
LEU A 385
GLN A 381
None
0.57A 3hznG-3eo4A:
undetectable
3hznH-3eo4A:
undetectable
3hznG-3eo4A:
20.89
3hznH-3eo4A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3epr HYDROLASE, HALOACID
DEHALOGENASE-LIKE
FAMILY


(Streptococcus
agalactiae)
PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6)
3 PRO A  66
LEU A  67
GLN A  55
None
0.55A 3hznG-3eprA:
undetectable
3hznH-3eprA:
undetectable
3hznG-3eprA:
20.22
3hznH-3eprA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eqx FIC DOMAIN
CONTAINING
TRANSCRIPTIONAL
REGULATOR


(Shewanella
oneidensis)
PF02661
(Fic)
PF13784
(Fic_N)
3 PRO A  14
LEU A  12
GLN A 193
None
0.60A 3hznG-3eqxA:
undetectable
3hznH-3eqxA:
undetectable
3hznG-3eqxA:
20.11
3hznH-3eqxA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fy4 6-4 PHOTOLYASE

(Arabidopsis
thaliana)
PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7)
3 PRO A 460
LEU A 461
GLN A 464
None
0.65A 3hznG-3fy4A:
undetectable
3hznH-3fy4A:
undetectable
3hznG-3fy4A:
18.89
3hznH-3fy4A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmb N-ACETYLMURAMOYL-L-A
LANINE AMIDASE XLYA


(Bacillus
subtilis)
PF01510
(Amidase_2)
3 PRO A  70
LEU A  71
GLN A  67
None
0.57A 3hznG-3hmbA:
undetectable
3hznH-3hmbA:
undetectable
3hznG-3hmbA:
20.59
3hznH-3hmbA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jyo QUINATE/SHIKIMATE
DEHYDROGENASE


(Corynebacterium
glutamicum)
PF08501
(Shikimate_dh_N)
3 PRO A 271
LEU A 269
GLN A  30
None
0.56A 3hznG-3jyoA:
undetectable
3hznH-3jyoA:
undetectable
3hznG-3jyoA:
23.13
3hznH-3jyoA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx2 PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE PRP43


(Saccharomyces
cerevisiae)
no annotation 3 PRO B 263
LEU B 264
GLN B 256
None
0.71A 3hznG-3kx2B:
undetectable
3hznH-3kx2B:
undetectable
3hznG-3kx2B:
15.01
3hznH-3kx2B:
15.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l6r SERINE RACEMASE

(Homo sapiens)
PF00291
(PALP)
3 PRO A  27
LEU A  25
GLN A 173
None
0.70A 3hznG-3l6rA:
undetectable
3hznH-3l6rA:
undetectable
3hznG-3l6rA:
21.45
3hznH-3l6rA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mbr GLUTAMINE
CYCLOTRANSFERASE


(Xanthomonas
campestris)
PF05096
(Glu_cyclase_2)
3 PRO X 256
LEU X 257
GLN X  28
None
0.48A 3hznG-3mbrX:
undetectable
3hznH-3mbrX:
undetectable
3hznG-3mbrX:
21.32
3hznH-3mbrX:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3no5 UNCHARACTERIZED
PROTEIN


(Cupriavidus
pinatubonensis)
PF05853
(BKACE)
3 PRO A 165
LEU A 166
GLN A 157
None
0.44A 3hznG-3no5A:
undetectable
3hznH-3no5A:
undetectable
3hznG-3no5A:
25.35
3hznH-3no5A:
25.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oee ATP SYNTHASE SUBUNIT
ALPHA


(Saccharomyces
cerevisiae)
PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N)
3 PRO A 437
LEU A 438
GLN A 432
None
0.71A 3hznG-3oeeA:
undetectable
3hznH-3oeeA:
undetectable
3hznG-3oeeA:
19.09
3hznH-3oeeA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oo3 OXY PROTEIN

(Actinoplanes
teichomyceticus)
PF00067
(p450)
3 PRO A   4
LEU A   5
GLN A   8
None
0.69A 3hznG-3oo3A:
undetectable
3hznH-3oo3A:
undetectable
3hznG-3oo3A:
17.47
3hznH-3oo3A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ps9 TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC


(Escherichia
coli)
PF01266
(DAO)
PF05430
(Methyltransf_30)
3 PRO A 249
LEU A 250
GLN A 170
None
0.61A 3hznG-3ps9A:
undetectable
3hznH-3ps9A:
undetectable
3hznG-3ps9A:
15.29
3hznH-3ps9A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qdn PUTATIVE THIOREDOXIN
PROTEIN


(Salmonella
enterica)
PF00085
(Thioredoxin)
PF14559
(TPR_19)
PF14561
(TPR_20)
3 PRO A 175
LEU A 176
GLN A 179
None
0.73A 3hznG-3qdnA:
undetectable
3hznH-3qdnA:
undetectable
3hznG-3qdnA:
22.74
3hznH-3qdnA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qit POLYKETIDE SYNTHASE

(Moorea
producens)
PF00561
(Abhydrolase_1)
3 PRO A 126
LEU A 127
GLN A 250
None
0.70A 3hznG-3qitA:
undetectable
3hznH-3qitA:
undetectable
3hznG-3qitA:
19.66
3hznH-3qitA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rlf MALTOSE/MALTODEXTRIN
IMPORT ATP-BINDING
PROTEIN MALK


(Escherichia
coli)
PF00005
(ABC_tran)
PF08402
(TOBE_2)
3 PRO A 225
LEU A 221
GLN A 214
None
0.69A 3hznG-3rlfA:
undetectable
3hznH-3rlfA:
undetectable
3hznG-3rlfA:
22.89
3hznH-3rlfA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sag EXOSOME COMPONENT 10

(Homo sapiens)
PF00570
(HRDC)
PF01612
(DNA_pol_A_exo1)
3 PRO A 580
LEU A 581
GLN A 505
PRO  A 580 ( 1.1A)
LEU  A 581 ( 0.6A)
GLN  A 505 ( 0.6A)
0.69A 3hznG-3sagA:
undetectable
3hznH-3sagA:
undetectable
3hznG-3sagA:
17.87
3hznH-3sagA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u9p NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN


(Mus musculus)
PF00061
(Lipocalin)
3 PRO C  11
LEU C  12
GLN C 105
None
0.60A 3hznG-3u9pC:
undetectable
3hznH-3u9pC:
undetectable
3hznG-3u9pC:
21.52
3hznH-3u9pC:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3un9 NLR FAMILY MEMBER X1

(Homo sapiens)
PF13516
(LRR_6)
3 PRO A 671
LEU A 675
GLN A 668
None
0.54A 3hznG-3un9A:
undetectable
3hznH-3un9A:
undetectable
3hznG-3un9A:
20.58
3hznH-3un9A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg2 PATF

(Prochloron
didemni)
no annotation 3 PRO A  31
LEU A  35
GLN A  24
None
0.73A 3hznG-4bg2A:
undetectable
3hznH-4bg2A:
0.6
3hznG-4bg2A:
20.13
3hznH-4bg2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bgq CYCLIN-DEPENDENT
KINASE-LIKE 5


(Homo sapiens)
PF00069
(Pkinase)
3 PRO A 229
LEU A 230
GLN A 224
None
0.72A 3hznG-4bgqA:
undetectable
3hznH-4bgqA:
undetectable
3hznG-4bgqA:
21.16
3hznH-4bgqA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d0c BETA-2-MICROGLOBULIN

(Gallus gallus)
PF07654
(C1-set)
3 PRO B  89
LEU B  86
GLN B  90
None
0.71A 3hznG-4d0cB:
undetectable
3hznH-4d0cB:
undetectable
3hznG-4d0cB:
19.09
3hznH-4d0cB:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f6c AUSA REDUCTASE
DOMAIN PROTEIN


(Staphylococcus
aureus)
PF07993
(NAD_binding_4)
3 PRO A2043
LEU A2044
GLN A2289
None
0.70A 3hznG-4f6cA:
undetectable
3hznH-4f6cA:
undetectable
3hznG-4f6cA:
19.48
3hznH-4f6cA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g4s PROTEASOME ASSEMBLY
CHAPERONE 2


(Saccharomyces
cerevisiae)
PF09754
(PAC2)
3 PRO P  88
LEU P  41
GLN P  85
None
0.65A 3hznG-4g4sP:
undetectable
3hznH-4g4sP:
undetectable
3hznG-4g4sP:
20.94
3hznH-4g4sP:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jc8 HOPS COMPONENT VPS33

(Chaetomium
thermophilum)
PF00995
(Sec1)
3 PRO A 187
LEU A 185
GLN A 581
None
0.63A 3hznG-4jc8A:
undetectable
3hznH-4jc8A:
undetectable
3hznG-4jc8A:
16.01
3hznH-4jc8A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kvf RHAMNOSE ABC
TRANSPORTER,
PERIPLASMIC
RHAMNOSE-BINDING
PROTEIN


(Kribbella
flavida)
PF13407
(Peripla_BP_4)
3 PRO A  56
LEU A  57
GLN A 320
None
0.54A 3hznG-4kvfA:
undetectable
3hznH-4kvfA:
undetectable
3hznG-4kvfA:
23.14
3hznH-4kvfA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m5p NADPH DEHYDROGENASE

(Scheffersomyces
stipitis)
PF00724
(Oxidored_FMN)
3 PRO A 131
LEU A 129
GLN A  74
None
0.70A 3hznG-4m5pA:
undetectable
3hznH-4m5pA:
undetectable
3hznG-4m5pA:
21.67
3hznH-4m5pA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mtk VGRG1

(Pseudomonas
aeruginosa)
PF05954
(Phage_GPD)
3 PRO A  47
LEU A  48
GLN A  79
SO4  A 708 (-4.3A)
SO4  A 708 (-3.5A)
SO4  A 708 ( 4.6A)
0.72A 3hznG-4mtkA:
undetectable
3hznH-4mtkA:
undetectable
3hznG-4mtkA:
15.32
3hznH-4mtkA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4myd 2-SUCCINYL-6-HYDROXY
-2,4-CYCLOHEXADIENE-
1-CARBOXYLATE
SYNTHASE


(Escherichia
coli)
PF12697
(Abhydrolase_6)
3 PRO A 113
LEU A 191
GLN A 188
None
0.72A 3hznG-4mydA:
undetectable
3hznH-4mydA:
undetectable
3hznG-4mydA:
22.30
3hznH-4mydA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlo HOMOSERINE
O-ACETYLTRANSFERASE


(Staphylococcus
aureus)
PF00561
(Abhydrolase_1)
3 PRO A  38
LEU A  39
GLN A  77
None
0.64A 3hznG-4qloA:
undetectable
3hznH-4qloA:
undetectable
3hznG-4qloA:
21.37
3hznH-4qloA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qvj VP1

(Norwalk virus)
PF08435
(Calici_coat_C)
3 PRO A 352
LEU A 353
GLN A 349
None
0.41A 3hznG-4qvjA:
undetectable
3hznH-4qvjA:
undetectable
3hznG-4qvjA:
22.06
3hznH-4qvjA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxd 3'(2'),5'-BISPHOSPHA
TE NUCLEOTIDASE,
PUTATIVE


(Entamoeba
histolytica)
PF00459
(Inositol_P)
3 PRO A 163
LEU A 164
GLN A 207
None
0.42A 3hznG-4qxdA:
undetectable
3hznH-4qxdA:
undetectable
3hznG-4qxdA:
20.27
3hznH-4qxdA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r8l UNCHARACTERIZED
PROTEIN


(Cavia porcellus)
PF00710
(Asparaginase)
3 PRO A  81
LEU A  82
GLN A  80
None
0.68A 3hznG-4r8lA:
undetectable
3hznH-4r8lA:
undetectable
3hznG-4r8lA:
21.30
3hznH-4r8lA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ric FANCONI-ASSOCIATED
NUCLEASE 1


(Homo sapiens)
PF08774
(VRR_NUC)
3 PRO A 867
LEU A 868
GLN A 864
None
0.44A 3hznG-4ricA:
undetectable
3hznH-4ricA:
undetectable
3hznG-4ricA:
17.52
3hznH-4ricA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tqv ALGS

(Sphingomonas
sp.)
PF00005
(ABC_tran)
PF03459
(TOBE)
3 PRO C 226
LEU C 222
GLN C 215
None
0.68A 3hznG-4tqvC:
undetectable
3hznH-4tqvC:
undetectable
3hznG-4tqvC:
22.71
3hznH-4tqvC:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4urt NETRIN RECEPTOR DCC

(Homo sapiens)
PF00041
(fn3)
3 PRO B1032
LEU B1033
GLN B1023
None
0.52A 3hznG-4urtB:
undetectable
3hznH-4urtB:
undetectable
3hznG-4urtB:
19.57
3hznH-4urtB:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wbo RHODOPSIN KINASE

(Bos taurus)
PF00069
(Pkinase)
PF00615
(RGS)
3 PRO A  43
LEU A  44
GLN A 173
None
0.61A 3hznG-4wboA:
undetectable
3hznH-4wboA:
undetectable
3hznG-4wboA:
18.29
3hznH-4wboA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wpz CYTOCHROME P450

(Streptomyces
avermitilis)
PF00067
(p450)
3 PRO A 284
LEU A 285
GLN A 247
None
HEM  A 503 (-4.3A)
HEM  A 503 ( 4.7A)
0.67A 3hznG-4wpzA:
undetectable
3hznH-4wpzA:
undetectable
3hznG-4wpzA:
20.60
3hznH-4wpzA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xai MALTOSE-BINDING
PERIPLASMIC
PROTEIN,TAILLESS
ORTHOLOG


(Escherichia
coli;
Tribolium
castaneum)
PF00104
(Hormone_recep)
PF13416
(SBP_bac_8)
3 PRO A1224
LEU A1225
GLN A1228
None
0.73A 3hznG-4xaiA:
undetectable
3hznH-4xaiA:
undetectable
3hznG-4xaiA:
20.00
3hznH-4xaiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yr6 HEAVY CHAIN OF 5G6

(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
3 PRO A  14
LEU A  12
GLN A  16
None
0.66A 3hznG-4yr6A:
undetectable
3hznH-4yr6A:
undetectable
3hznG-4yr6A:
17.98
3hznH-4yr6A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzf FAB FRAGMENT OF
IMMUNOGLOBULIN (IGG)
MOLECULE


(Mus musculus)
PF07654
(C1-set)
PF07686
(V-set)
3 PRO E  14
LEU E  12
GLN E  16
None
0.73A 3hznG-4yzfE:
undetectable
3hznH-4yzfE:
undetectable
3hznG-4yzfE:
20.70
3hznH-4yzfE:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zvi DNA GYRASE SUBUNIT B

(Escherichia
coli)
PF00204
(DNA_gyraseB)
PF02518
(HATPase_c)
3 PRO A 153
LEU A 154
GLN A 143
None
0.60A 3hznG-4zviA:
undetectable
3hznH-4zviA:
undetectable
3hznG-4zviA:
21.01
3hznH-4zviA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5buk FADH2-DEPENDENT
HALOGENASE


(Streptomyces
sp. CNQ-418)
PF04820
(Trp_halogenase)
3 PRO A 290
LEU A 291
GLN A 287
None
0.56A 3hznG-5bukA:
undetectable
3hznH-5bukA:
undetectable
3hznG-5bukA:
21.43
3hznH-5bukA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dn6 ATP SYNTHASE SUBUNIT
ALPHA


(Paracoccus
denitrificans)
PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N)
3 PRO A 436
LEU A 437
GLN A 431
None
0.65A 3hznG-5dn6A:
undetectable
3hznH-5dn6A:
undetectable
3hznG-5dn6A:
17.74
3hznH-5dn6A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dne L-ASPARAGINASE

(Cavia porcellus)
PF00710
(Asparaginase)
3 PRO A  81
LEU A  82
GLN A  80
None
0.61A 3hznG-5dneA:
undetectable
3hznH-5dneA:
undetectable
3hznG-5dneA:
17.35
3hznH-5dneA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e3t PHOSPHATIDYLINOSITOL
-4-PHOSPHATE
5-KINASE, TYPE I,
ALPHA


(Danio rerio)
PF01504
(PIP5K)
3 PRO A 146
LEU A 147
GLN A  67
None
0.66A 3hznG-5e3tA:
undetectable
3hznH-5e3tA:
1.4
3hznG-5e3tA:
19.35
3hznH-5e3tA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5exx TRANSCRIPTIONAL
REGULATOR FLEQ


(Pseudomonas
aeruginosa)
PF00158
(Sigma54_activat)
3 PRO A 251
LEU A 252
GLN A 255
None
0.72A 3hznG-5exxA:
undetectable
3hznH-5exxA:
undetectable
3hznG-5exxA:
23.48
3hznH-5exxA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fo3 CELL DIVISION
PROTEIN ZAPC


(Escherichia
coli)
PF07126
(ZapC)
3 PRO A  90
LEU A  88
GLN A  91
None
0.55A 3hznG-5fo3A:
undetectable
3hznH-5fo3A:
undetectable
3hznG-5fo3A:
23.14
3hznH-5fo3A:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fql IDURONATE-2-SULFATAS
E


(Homo sapiens)
PF00884
(Sulfatase)
3 PRO A 243
LEU A 244
GLN A 298
NAG  A1558 ( 4.6A)
None
None
0.32A 3hznG-5fqlA:
undetectable
3hznH-5fqlA:
undetectable
3hznG-5fqlA:
17.29
3hznH-5fqlA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gli ENDOTHELIN RECEPTOR
SUBTYPE-B


(Homo sapiens)
PF00001
(7tm_1)
PF00959
(Phage_lysozyme)
3 PRO A 259
LEU A 257
GLN A 261
None
0.64A 3hznG-5gliA:
undetectable
3hznH-5gliA:
undetectable
3hznG-5gliA:
18.81
3hznH-5gliA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jff UNCHARACTERIZED
PROTEIN YHFG


(Escherichia
coli)
PF10832
(DUF2559)
3 PRO B  33
LEU B  34
GLN B  22
None
0.59A 3hznG-5jffB:
undetectable
3hznH-5jffB:
undetectable
3hznG-5jffB:
14.55
3hznH-5jffB:
14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jkp UNCHARACTERIZED
PROTEIN


(Pseudomonas
aeruginosa)
PF08238
(Sel1)
3 PRO A 273
LEU A 274
GLN A 210
None
0.64A 3hznG-5jkpA:
undetectable
3hznH-5jkpA:
undetectable
3hznG-5jkpA:
21.55
3hznH-5jkpA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lk7 VP1

(Slow bee
paralysis virus)
PF08762
(CRPV_capsid)
3 PRO A  14
LEU A  15
GLN A  11
None
0.66A 3hznG-5lk7A:
undetectable
3hznH-5lk7A:
undetectable
3hznG-5lk7A:
19.12
3hznH-5lk7A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lta PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE PRP43


(Chaetomium
thermophilum)
PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind)
3 PRO A 266
LEU A 267
GLN A 259
None
0.72A 3hznG-5ltaA:
undetectable
3hznH-5ltaA:
undetectable
3hznG-5ltaA:
15.32
3hznH-5ltaA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlp UNCHARACTERIZED
PROTEIN


(Rickettsiella
grylli)
no annotation 3 PRO A  76
LEU A  77
GLN A  70
None
0.52A 3hznG-5mlpA:
undetectable
3hznH-5mlpA:
undetectable
3hznG-5mlpA:
undetectable
3hznH-5mlpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wvg CHITINASE

(Ostrinia
furnacalis)
no annotation 3 PRO A 733
LEU A 734
GLN A 826
None
0.63A 3hznG-5wvgA:
undetectable
3hznH-5wvgA:
undetectable
3hznG-5wvgA:
undetectable
3hznH-5wvgA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byi BETA-MANNOSIDASE

(Xanthomonas
citri)
no annotation 3 PRO A  46
LEU A  44
GLN A  48
None
0.63A 3hznG-6byiA:
undetectable
3hznH-6byiA:
undetectable
3hznG-6byiA:
undetectable
3hznH-6byiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dfp VCA0883

(Vibrio cholerae)
no annotation 3 PRO A 363
LEU A 361
GLN A 247
None
0.70A 3hznG-6dfpA:
undetectable
3hznH-6dfpA:
undetectable
3hznG-6dfpA:
undetectable
3hznH-6dfpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6etz BETA-GALACTOSIDASE

(Arthrobacter
sp. 32cB)
no annotation 3 PRO A 780
LEU A 781
GLN A 784
None
0.73A 3hznG-6etzA:
undetectable
3hznH-6etzA:
undetectable
3hznG-6etzA:
undetectable
3hznH-6etzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eys -

(-)
no annotation 3 PRO B 246
LEU B 247
GLN B 243
None
0.72A 3hznG-6eysB:
undetectable
3hznH-6eysB:
undetectable
3hznG-6eysB:
undetectable
3hznH-6eysB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE SUBUNIT
ALPHA, CHLOROPLASTIC


(Spinacia
oleracea)
no annotation 3 PRO C 428
LEU C 429
GLN C 423
None
0.70A 3hznG-6fkhC:
undetectable
3hznH-6fkhC:
undetectable
3hznG-6fkhC:
undetectable
3hznH-6fkhC:
undetectable