SIMILAR PATTERNS OF AMINO ACIDS FOR 3HUO_A_PNNA304

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bdo ACETYL-COA
CARBOXYLASE

(Escherichia
coli) 		PF00364
(Biotin_lipoyl) 		4 GLN A 144
PRO A 145
VAL A 146
GLU A 147
 None
 1.39A 3huoA-1bdoA:
0.0		 3huoA-1bdoA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1evq SERINE HYDROLASE

(Alicyclobacillus
acidocaldarius) 		PF07859
(Abhydrolase_3) 		4 GLN A 179
PRO A 243
VAL A 272
GLU A 273
 None
 1.27A 3huoA-1evqA:
0.0		 3huoA-1evqA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ig8 HEXOKINASE PII

(Saccharomyces
cerevisiae) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 GLN A 193
PRO A 190
VAL A 189
GLU A 168
 None
 1.14A 3huoA-1ig8A:
0.0		 3huoA-1ig8A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lxy ARGININE DEIMINASE

(Mycoplasma
arginini) 		PF02274
(Amidinotransf) 		4 GLN A 307
PRO A 308
VAL A 309
GLU A 310
 None
 1.28A 3huoA-1lxyA:
0.0		 3huoA-1lxyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ofe FERREDOXIN-DEPENDENT
GLUTAMATE SYNTHASE 2

(Synechocystis
sp. PCC 6803) 		PF00310
(GATase_2)
PF01493
(GXGXG)
PF01645
(Glu_synthase)
PF04898
(Glu_syn_central) 		4 GLN A 467
PRO A 463
VAL A 462
GLU A 458
 None
 1.37A 3huoA-1ofeA:
0.0		 3huoA-1ofeA:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1siv SIV PROTEASE

(Simian
immunodeficiency
virus) 		PF00077
(RVP) 		4 GLN A  18
PRO A  19
VAL A  20
GLU A  21
 None
 1.38A 3huoA-1sivA:
0.0		 3huoA-1sivA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE
F1-ATPASE

(Bacillus sp.
PS3;
Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF00306
(ATP-synt_ab_C)
PF02874
(ATP-synt_ab_N)
PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 GLN B 113
PRO B 114
VAL B 115
GLU E 126
 None
 0.91A 3huoA-1skyB:
0.0		 3huoA-1skyB:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t6k PHENAZINE
BIOSYNTHESIS PROTEIN
PHZF

(Pseudomonas
fluorescens) 		PF02567
(PhzC-PhzF) 		4 GLN A 232
PRO A 233
VAL A 234
GLU A 235
 None
 0.84A 3huoA-1t6kA:
0.0		 3huoA-1t6kA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ytq BETA CRYSTALLIN B2

(Homo sapiens) 		PF00030
(Crystall) 		4 GLN A 182
PRO A 181
VAL A 140
GLU A 112
 None
 1.18A 3huoA-1ytqA:
undetectable		 3huoA-1ytqA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zy1 PEPTIDE DEFORMYLASE,
MITOCHONDRIAL

(Arabidopsis
thaliana) 		PF01327
(Pep_deformylase) 		4 GLN A  54
PRO A  53
VAL A  13
GLU A  16
 ZN  A 198 (-3.4A)
None
None
None
 1.46A 3huoA-1zy1A:
undetectable		 3huoA-1zy1A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bb2 BETA B2-CRYSTALLIN

(Bos taurus) 		PF00030
(Crystall) 		4 GLN A 163
PRO A 162
VAL A 121
GLU A  94
 None
 1.09A 3huoA-2bb2A:
undetectable		 3huoA-2bb2A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hmi FAB FRAGMENT OF
MONOCLONAL ANTIBODY
28

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLN D  16
PRO D  14
VAL D  87
GLU D  88
 None
 1.11A 3huoA-2hmiD:
undetectable		 3huoA-2hmiD:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inp PHENOL HYDROXYLASE
COMPONENT PHN

(Pseudomonas
stutzeri) 		PF02332
(Phenol_Hydrox)
PF04945
(YHS) 		4 GLN A 259
PRO A 256
VAL A 255
GLU A 252
 None
 1.23A 3huoA-2inpA:
undetectable		 3huoA-2inpA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lem APOLIPOPROTEIN A-I

(Mus musculus) 		PF01442
(Apolipoprotein) 		4 GLN A  97
PRO A  98
VAL A  96
GLU A 102
 None
 0.98A 3huoA-2lemA:
undetectable		 3huoA-2lemA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nbr GAMMA-CRYSTALLIN C

(Homo sapiens) 		PF00030
(Crystall) 		4 GLN A 148
PRO A 147
VAL A 125
GLU A 127
 None
 1.47A 3huoA-2nbrA:
undetectable		 3huoA-2nbrA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o7q BIFUNCTIONAL
3-DEHYDROQUINATE
DEHYDRATASE/SHIKIMAT
E DEHYDROGENASE

(Arabidopsis
thaliana) 		PF01487
(DHquinase_I)
PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 GLN A 526
PRO A 527
VAL A 529
GLU A 531
 None
 1.50A 3huoA-2o7qA:
undetectable		 3huoA-2o7qA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ohg GLUTAMATE RACEMASE

(Streptococcus
pyogenes) 		PF01177
(Asp_Glu_race) 		4 GLN A 246
PRO A 242
VAL A 259
GLU A 260
 None
 1.47A 3huoA-2ohgA:
undetectable		 3huoA-2ohgA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pof CDP-DIACYLGLYCEROL
PYROPHOSPHATASE

(Escherichia
coli) 		PF02611
(CDH) 		4 GLN A  47
PRO A  60
VAL A  58
GLU A  57
 None
 1.44A 3huoA-2pofA:
undetectable		 3huoA-2pofA:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qu7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Staphylococcus
saprophyticus) 		PF13407
(Peripla_BP_4) 		4 GLN A 296
PRO A 297
VAL A 298
GLU A  84
 None
 1.48A 3huoA-2qu7A:
undetectable		 3huoA-2qu7A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ya1 PUTATIVE ALKALINE
AMYLOPULLULANASE

(Streptococcus
pneumoniae) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48)
PF03714
(PUD) 		4 GLN A1054
PRO A1052
VAL A1057
GLU A1058
 None
 1.38A 3huoA-2ya1A:
undetectable		 3huoA-2ya1A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ziu MUS81 PROTEIN
CROSSOVER JUNCTION
ENDONUCLEASE EME1

(Danio rerio;
Homo sapiens) 		PF02732
(ERCC4)
PF02732
(ERCC4) 		4 GLN B 561
PRO B 562
VAL A 532
GLU A 534
 None
 0.92A 3huoA-2ziuB:
undetectable		 3huoA-2ziuB:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3exq NUDIX FAMILY
HYDROLASE

(Lactobacillus
brevis) 		PF00293
(NUDIX) 		4 GLN A   7
PRO A   8
VAL A   9
GLU A  10
 None
 0.99A 3huoA-3exqA:
undetectable		 3huoA-3exqA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hr8 PROTEIN RECA

(Thermotoga
maritima) 		PF00154
(RecA) 		4 GLN A  37
PRO A  38
VAL A  39
GLU A  40
 None
 1.24A 3huoA-3hr8A:
undetectable		 3huoA-3hr8A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kt9 APRATAXIN

(Homo sapiens) 		PF00498
(FHA) 		4 GLN A  85
PRO A  83
VAL A  98
GLU A  99
 None
 1.43A 3huoA-3kt9A:
undetectable		 3huoA-3kt9A:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lyr TRANSCRIPTION FACTOR
COE1

(Homo sapiens) 		PF16422
(COE1_DBD) 		4 GLN A  80
PRO A  81
VAL A  82
GLU A  83
 None
 1.13A 3huoA-3lyrA:
undetectable		 3huoA-3lyrA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mlp TRANSCRIPTION FACTOR
COE1

(Mus musculus) 		PF01833
(TIG)
PF16422
(COE1_DBD)
PF16423
(COE1_HLH) 		4 GLN A  80
PRO A  81
VAL A  82
GLU A  83
 None
 1.29A 3huoA-3mlpA:
undetectable		 3huoA-3mlpA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p1v METALLO-ENDOPEPTIDAS
E

(Bacteroides
ovatus) 		PF09471
(Peptidase_M64)
PF16217
(M64_N) 		4 GLN A 122
PRO A 123
VAL A 124
GLU A 125
 None
 1.36A 3huoA-3p1vA:
undetectable		 3huoA-3p1vA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pqd L-LACTATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 GLN A  59
PRO A  60
VAL A  61
GLU A  32
 None
 1.02A 3huoA-3pqdA:
undetectable		 3huoA-3pqdA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q0i METHIONYL-TRNA
FORMYLTRANSFERASE

(Vibrio cholerae) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		4 GLN A 298
PRO A 296
VAL A 297
GLU A 285
 None
 1.32A 3huoA-3q0iA:
undetectable		 3huoA-3q0iA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6g LIGHT CHAIN OF FAB
OF RHESUS MAB 2.5B

(Macaca mulatta) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLN L  17
PRO L  15
VAL L  78
GLU L  79
 None
 1.14A 3huoA-3q6gL:
undetectable		 3huoA-3q6gL:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s38 CYTOCHROME C OXIDASE
SUBUNIT 2

(Thermus
thermophilus) 		PF00116
(COX2)
PF09125
(COX2-transmemb) 		4 GLN B  99
PRO B  98
VAL B 166
GLU B  96
 None
 1.16A 3huoA-3s38B:
undetectable		 3huoA-3s38B:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usz EXO-1,3/1,4-BETA-GLU
CANASE

(Pseudoalteromonas
sp. BB1) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		4 GLN A  43
PRO A  44
VAL A 321
GLU A 323
 None
 1.26A 3huoA-3uszA:
undetectable		 3huoA-3uszA:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wad GLYCOSYLTRANSFERASE

(Streptomyces
halstedii) 		PF06722
(DUF1205) 		4 GLN A 336
PRO A 335
VAL A 334
GLU A 390
 None
 1.43A 3huoA-3wadA:
undetectable		 3huoA-3wadA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wzf ASPARTATE
AMINOTRANSFERASE,
CYTOPLASMIC

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		4 GLN A  11
PRO A  10
VAL A   9
GLU A   8
 None
 1.36A 3huoA-3wzfA:
undetectable		 3huoA-3wzfA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis) 		PF00141
(peroxidase) 		4 GLN A 500
PRO A 501
VAL A 581
GLU A 582
 None
 1.32A 3huoA-4c51A:
undetectable		 3huoA-4c51A:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h61 MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 6

(Schizosaccharomyces
pombe) 		PF04934
(Med6) 		4 GLN A  92
PRO A 104
VAL A 102
GLU A 101
 None
 1.50A 3huoA-4h61A:
undetectable		 3huoA-4h61A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hk0 UCA LIGHT CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLN B  16
PRO B  14
VAL B  77
GLU B  78
 None
 1.11A 3huoA-4hk0B:
undetectable		 3huoA-4hk0B:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hr7 BIOTIN CARBOXYL
CARRIER PROTEIN OF
ACETYL-COA
CARBOXYLASE

(Escherichia
coli) 		PF00364
(Biotin_lipoyl) 		4 GLN B 144
PRO B 145
VAL B 146
GLU B 147
 None
 1.23A 3huoA-4hr7B:
undetectable		 3huoA-4hr7B:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oe6 DELTA-1-PYRROLINE-5-
CARBOXYLATE
DEHYDROGENASE,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00171
(Aldedh) 		4 GLN A 184
PRO A 185
VAL A 186
GLU A 187
 None
 0.71A 3huoA-4oe6A:
undetectable		 3huoA-4oe6A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p17 RABGAP/TBC PROTEIN

(Chlamydomonas
reinhardtii) 		PF00566
(RabGAP-TBC) 		4 GLN A  41
PRO A  38
VAL A  37
GLU A  34
 None
 1.21A 3huoA-4p17A:
undetectable		 3huoA-4p17A:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qgk FATTY ALDEHYDE
DEHYDROGENASE

(Homo sapiens) 		PF00171
(Aldedh) 		4 GLN A  98
PRO A  99
VAL A  79
GLU A  77
 None
 1.40A 3huoA-4qgkA:
undetectable		 3huoA-4qgkA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yys FICIN ISOFORM B

(Ficus carica) 		PF00112
(Peptidase_C1) 		4 GLN A 131
PRO A 132
VAL A  33
GLU A  35
 None
 1.10A 3huoA-4yysA:
undetectable		 3huoA-4yysA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yyw FICIN ISOFORM D

(Ficus carica) 		PF00112
(Peptidase_C1) 		4 GLN A 131
PRO A 132
VAL A  33
GLU A  35
 None
 1.14A 3huoA-4yywA:
undetectable		 3huoA-4yywA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f9q MACROLIDE EXPORT
ATP-BINDING/PERMEASE
PROTEIN YKNZ

(Bacillus
amyloliquefaciens) 		PF12704
(MacB_PCD) 		4 GLN A 138
PRO A 139
VAL A 140
GLU A 141
 None
 1.20A 3huoA-5f9qA:
undetectable		 3huoA-5f9qA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hzw MALTOSE-BINDING
PERIPLASMIC
PROTEIN,ENDOGLIN

(Escherichia
coli;
Homo sapiens) 		PF13416
(SBP_bac_8) 		4 GLN A 448
PRO A 718
VAL A 623
GLU A 716
 None
 1.41A 3huoA-5hzwA:
undetectable		 3huoA-5hzwA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lnk MITOCHONDRIAL
COMPLEX I, 39 KDA
SUBUNIT

(Ovis aries) 		no annotation 4 GLN d 115
PRO d 114
VAL d 156
GLU d 153
 None
 1.45A 3huoA-5lnkd:
undetectable		 3huoA-5lnkd:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nge UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 7

(Homo sapiens) 		no annotation 4 GLN A 261
PRO A 257
VAL A 307
GLU A 308
 None
 1.44A 3huoA-5ngeA:
undetectable		 3huoA-5ngeA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sv2 RIBONUCLEASE VAPC21

(Mycobacterium
tuberculosis) 		PF01850
(PIN) 		4 GLN A 127
PRO A 128
VAL A 129
GLU A 130
 None
 1.20A 3huoA-5sv2A:
undetectable		 3huoA-5sv2A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3p PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7

(Homo sapiens) 		PF00293
(NUDIX) 		4 GLN A 136
PRO A 137
VAL A  98
GLU A 141
 None
 1.35A 3huoA-5t3pA:
undetectable		 3huoA-5t3pA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t4m PROTOCADHERIN-15

(Homo sapiens) 		PF00028
(Cadherin) 		4 GLN A 446
PRO A 447
VAL A 448
GLU A 385
 None
None
None
CA  A 704 ( 2.8A)
 1.00A 3huoA-5t4mA:
undetectable		 3huoA-5t4mA:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5te6 HEAVY CHAIN OF N6

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 GLN H  53
PRO H  52
VAL H  73
GLU H  76
 None
 1.19A 3huoA-5te6H:
undetectable		 3huoA-5te6H:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vni PROTEIN TRANSPORT
PROTEIN SEC24A

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 GLN B 933
PRO B 934
VAL B 936
GLU B 384
 None
 1.34A 3huoA-5vniB:
undetectable		 3huoA-5vniB:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w1d PROTOCADHERIN-15

(Mus musculus) 		no annotation 4 GLN A 446
PRO A 447
VAL A 448
GLU A 385
 None
None
None
CA  A1007 (-2.9A)
 0.88A 3huoA-5w1dA:
undetectable		 3huoA-5w1dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cuf -

(-) 		no annotation 4 GLN 6  17
PRO 6  15
VAL 6  78
GLU 6  79
 None
 1.06A 3huoA-6cuf6:
undetectable		 3huoA-6cuf6:
undetectable