SIMILAR PATTERNS OF AMINO ACIDS FOR 3HUO_A_PNNA303_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fbw | ENDO-1,4-BETA-GLUCANASE F ([Clostridium]cellulolyticum) |
PF02011(Glyco_hydro_48) | 4 | GLN A 356GLN A 324GLY A 322HIS A 320 | None | 1.41A | 3huoA-1fbwA:0.0 | 3huoA-1fbwA:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mwi | G/UMISMATCH-SPECIFICDNA GLYCOSYLASE (Escherichiacoli) |
PF03167(UDG) | 4 | GLN A 110GLN A 114GLY A 115HIS A 86 | None | 1.18A | 3huoA-1mwiA:0.0 | 3huoA-1mwiA:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nbu | PROBABLEDIHYDRONEOPTERINALDOLASE (Mycobacteriumtuberculosis) |
PF02152(FolB) | 4 | GLN B 101GLN B 27GLY B 14HIS B 16 | None | 1.25A | 3huoA-1nbuB:0.0 | 3huoA-1nbuB:20.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pk6 | COMPLEMENT C1QSUBCOMPONENT, ACHAIN PRECURSORCOMPLEMENT C1QSUBCOMPONENT, CCHAIN PRECURSOR (Homo sapiens;Homo sapiens) |
PF00386(C1q)PF00386(C1q) | 4 | GLN A 177GLN C 173GLY C 166HIS C 167 | CA B 1 (-3.2A) CA B 1 ( 4.7A)NoneNone | 1.39A | 3huoA-1pk6A:0.2 | 3huoA-1pk6A:17.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qni | NITROUS-OXIDEREDUCTASE (Marinobacterhydrocarbonoclasticus) |
no annotation | 4 | GLN A 371GLN A 415GLY A 430HIS A 428 | None | 1.42A | 3huoA-1qniA:0.0 | 3huoA-1qniA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r4n | AMYLOID BETAPRECURSORPROTEIN-BINDINGPROTEIN 1 (Homo sapiens) |
PF00899(ThiF) | 4 | GLN A 16GLN A 25GLY A 21HIS A 23 | None | 1.47A | 3huoA-1r4nA:0.0 | 3huoA-1r4nA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uru | AMPHIPHYSIN (Drosophilamelanogaster) |
PF03114(BAR) | 4 | GLN A 174GLN A 148GLY A 147HIS A 150 | None | 1.44A | 3huoA-1uruA:undetectable | 3huoA-1uruA:23.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yif | BETA-1,4-XYLOSIDASE (Bacillussubtilis) |
PF04616(Glyco_hydro_43) | 4 | GLN A 421GLN A 514GLY A 367HIS A 368 | None | 1.15A | 3huoA-1yifA:0.0 | 3huoA-1yifA:18.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nlz | CEPHALOSPORINACYLASE (Bacillushalodurans) |
PF01019(G_glu_transpept) | 4 | GLN A 472GLN A 446GLY A 447HIS A 448 | None | 1.11A | 3huoA-2nlzA:0.0 | 3huoA-2nlzA:20.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yeq | ALKALINE PHOSPHATASED (Bacillussubtilis) |
PF09423(PhoD)PF16655(PhoD_N) | 4 | GLN A 330GLN A 331GLY A 150HIS A 148 | None | 1.41A | 3huoA-2yeqA:undetectable | 3huoA-2yeqA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9y | ACETOLACTATESYNTHASE,CHLOROPLASTIC (Arabidopsisthaliana) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | GLN A 573GLN A 487GLY A 486HIS A 488 | NoneTDM A 700 (-4.9A)TDM A 700 (-3.4A)TDM A 700 (-4.1A) | 1.10A | 3huoA-3e9yA:undetectable | 3huoA-3e9yA:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k30 | HISTAMINEDEHYDROGENASE (Pimelobactersimplex) |
PF00724(Oxidored_FMN)PF07992(Pyr_redox_2) | 4 | GLN A 574GLN A 559GLY A 557HIS A 533 | None | 1.44A | 3huoA-3k30A:undetectable | 3huoA-3k30A:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mw3 | NEUREXIN-2-BETA (Rattusnorvegicus) |
PF02210(Laminin_G_2) | 4 | GLN A 123GLN A 257GLY A 95HIS A 286 | None | 1.45A | 3huoA-3mw3A:undetectable | 3huoA-3mw3A:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qh4 | ESTERASE LIPW (Mycobacteriummarinum) |
PF07859(Abhydrolase_3) | 4 | GLN A 103GLN A 303GLY A 304HIS A 305 | None | 1.18A | 3huoA-3qh4A:undetectable | 3huoA-3qh4A:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bed | HEMOCYANIN KLH1 (Megathuracrenulata) |
PF00264(Tyrosinase)PF14830(Haemocyan_bet_s) | 4 | GLN B2415GLN B2400GLY B2413HIS B2411 | None | 1.41A | 3huoA-4bedB:undetectable | 3huoA-4bedB:9.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwr | PROTEINCORRESPONDING TOLOCUS C5321 FROMCFT073 E.COLI STRAIN (Escherichiacoli) |
PF08238(Sel1) | 4 | GLN A 225GLN A 199GLY A 198HIS A 201 | None | 1.44A | 3huoA-4bwrA:undetectable | 3huoA-4bwrA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4el8 | GLYCOSIDE HYDROLASEFAMILY 48 (Caldicellulosiruptorbescii) |
PF02011(Glyco_hydro_48) | 4 | GLN A 357GLN A 325GLY A 323HIS A 321 | None | 1.41A | 3huoA-4el8A:undetectable | 3huoA-4el8A:17.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fye | SIDF, INHIBITOR OFGROWTH FAMILY,MEMBER 3 (Legionellapneumophila) |
no annotation | 4 | GLN A 657GLN A 703GLY A 716HIS A 707 | None | 1.46A | 3huoA-4fyeA:undetectable | 3huoA-4fyeA:15.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hb4 | EXPORTIN-1 (Saccharomycescerevisiae) |
PF03810(IBN_N)PF08389(Xpo1)PF08767(CRM1_C) | 4 | GLN C 640GLN C 592GLY C 590HIS C 588 | None | 1.36A | 3huoA-4hb4C:undetectable | 3huoA-4hb4C:13.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l37 | SILKWORM STORAGEPROTEIN (Bombyx mori) |
PF00372(Hemocyanin_M)PF03722(Hemocyanin_N)PF03723(Hemocyanin_C) | 4 | GLN A 326GLN A 327GLY A 328HIS A 329 | None | 1.42A | 3huoA-4l37A:undetectable | 3huoA-4l37A:16.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m2g | L-ARGININEBETA-HYDROXYLASE (Streptomyceslavendulae) |
PF02668(TauD) | 4 | GLN A 81GLN A 290GLY A 291HIS A 77 | None | 1.24A | 3huoA-4m2gA:undetectable | 3huoA-4m2gA:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xwl | EXOGLUCANASE S (Clostridiumcellulovorans) |
PF02011(Glyco_hydro_48) | 4 | GLN A 348GLN A 316GLY A 314HIS A 312 | None | 1.46A | 3huoA-4xwlA:undetectable | 3huoA-4xwlA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bv9 | CELLULOSE1,4-BETA-CELLOBIOSIDASE (Bacilluspumilus) |
PF02011(Glyco_hydro_48) | 4 | GLN A 356GLN A 323GLY A 321HIS A 319 | None | 1.48A | 3huoA-5bv9A:undetectable | 3huoA-5bv9A:15.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c92 | KELCHDOMAIN-CONTAININGPROTEIN (Colletotrichumgraminicola) |
PF01344(Kelch_1)PF09118(DUF1929) | 4 | GLN A 298GLN A 309GLY A 295HIS A 328 | None | 1.42A | 3huoA-5c92A:undetectable | 3huoA-5c92A:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5czy | LEGIONELLA EFFECTORLEGAS4 (Legionellapneumophila) |
PF00023(Ank)PF00856(SET) | 4 | GLN A 199GLN A 363GLY A 368HIS A 369 | None | 1.21A | 3huoA-5czyA:undetectable | 3huoA-5czyA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hkj | COMPLEMENT C1QSUBCOMPONENT SUBUNITA,COMPLEMENT C1QSUBCOMPONENT SUBUNITC,COMPLEMENT C1QSUBCOMPONENT SUBUNITB (Homo sapiens) |
PF00386(C1q) | 4 | GLN A 90GLN A 226GLY A 219HIS A 220 | CA A 502 (-3.0A) CA A 502 ( 4.7A)NoneNone | 1.31A | 3huoA-5hkjA:undetectable | 3huoA-5hkjA:20.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbg | LGP2 (Gallus gallus) |
PF00271(Helicase_C)PF04851(ResIII)PF11648(RIG-I_C-RD) | 4 | GLN A 357GLN A 394GLY A 393HIS A 395 | None | 1.43A | 3huoA-5jbgA:undetectable | 3huoA-5jbgA:16.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vni | PROTEIN TRANSPORTPROTEIN SEC24A (Homo sapiens) |
PF00626(Gelsolin)PF04810(zf-Sec23_Sec24)PF04811(Sec23_trunk)PF04815(Sec23_helical)PF08033(Sec23_BS) | 4 | GLN B 929GLN B 933GLY B 784HIS B 412 | None | 1.20A | 3huoA-5vniB:undetectable | 3huoA-5vniB:16.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yj6 | DOCKERIN TYPE IREPEAT-CONTAININGPROTEIN (Ruminiclostridiumthermocellum) |
no annotation | 4 | GLN A 384GLN A 352GLY A 350HIS A 348 | None | 1.48A | 3huoA-5yj6A:undetectable | 3huoA-5yj6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c49 | ALCOHOLDEHYDROGENASE (Acinetobacterbaumannii) |
no annotation | 4 | GLN A 107GLN A 134GLY A 132HIS A 31 | None | 1.41A | 3huoA-6c49A:undetectable | 3huoA-6c49A:undetectable |