SIMILAR PATTERNS OF AMINO ACIDS FOR 3HTH_A_PRLA201

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bas YKUI PROTEIN

(Bacillus
subtilis) 		PF00563
(EAL)
PF10388
(YkuI_C) 		5 PHE A 365
VAL A 268
LEU A 400
TYR A 369
ASP A 394
 None
 0.98A 3hthA-2basA:
0.7		 3hthA-2basA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gk8 HISTIDINOL-PHOSPHATA
SE

(Lactococcus
lactis) 		PF02811
(PHP) 		5 PHE A 152
VAL A 143
LEU A 136
TYR A 208
ASP A 156
 None
 1.15A 3hthA-4gk8A:
0.7		 3hthA-4gk8A:
20.83