SIMILAR PATTERNS OF AMINO ACIDS FOR 3HJO_B_EAAB211

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b25 PROTEIN
(FORMALDEHYDE
FERREDOXIN
OXIDOREDUCTASE)

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 PHE A  31
VAL A 529
ILE A   8
GLY A  33
 None
 0.83A 3hjoB-1b25A:
0.0		 3hjoB-1b25A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhe POLYGALACTURONASE

(Pectobacterium
carotovorum) 		PF00295
(Glyco_hydro_28) 		4 VAL A 304
VAL A 299
ASN A 277
GLY A 278
 None
 0.80A 3hjoB-1bheA:
0.0		 3hjoB-1bheA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c8o ICE INHIBITOR

(Cowpox virus) 		PF00079
(Serpin) 		4 PHE A 151
VAL A 161
VAL A 153
VAL A 240
 None
 0.77A 3hjoB-1c8oA:
undetectable		 3hjoB-1c8oA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dbr HYPOXANTHINE GUANINE
XANTHINE
PHOSPHORIBOSYLTRANSF
ERASE

(Toxoplasma
gondii) 		PF00156
(Pribosyltran) 		4 VAL A 142
VAL A 165
ILE A  77
VAL A 113
 None
 0.88A 3hjoB-1dbrA:
undetectable		 3hjoB-1dbrA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e7s GDP-FUCOSE
SYNTHETASE

(Escherichia
coli) 		PF01370
(Epimerase) 		4 TRP A 311
ILE A 260
VAL A 263
GLY A 304
 TRS  A1321 (-4.5A)
None
None
None
 0.83A 3hjoB-1e7sA:
0.1		 3hjoB-1e7sA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h1y D-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE

(Oryza sativa) 		PF00834
(Ribul_P_3_epim) 		4 VAL A 163
ILE A 197
VAL A 220
GLY A 193
 None
 0.88A 3hjoB-1h1yA:
undetectable		 3hjoB-1h1yA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hr7 MITOCHONDRIAL
PROCESSING PEPTIDASE
BETA SUBUNIT

(Saccharomyces
cerevisiae) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 VAL B 395
ILE B 119
VAL B 123
GLY B  51
 None
 0.77A 3hjoB-1hr7B:
0.0		 3hjoB-1hr7B:
20.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 PHE A   8
VAL A  10
VAL A  35
TRP A  38
 GSH  A 504 (-4.7A)
None
None
GSH  A 504 (-3.9A)
 0.12A 3hjoB-1lbkA:
36.1		 3hjoB-1lbkA:
96.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 PHE A   8
VAL A  35
TRP A  38
ILE A 104
 GSH  A 504 (-4.7A)
None
GSH  A 504 (-3.9A)
None
 0.55A 3hjoB-1lbkA:
36.1		 3hjoB-1lbkA:
96.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1llu ALCOHOL
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A  83
ILE A 149
VAL A  70
GLY A 138
 None
 0.88A 3hjoB-1lluA:
0.0		 3hjoB-1lluA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mld MALATE DEHYDROGENASE

(Sus scrofa) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 VAL A 172
ILE A 124
VAL A 120
GLY A 175
 None
 0.81A 3hjoB-1mldA:
undetectable		 3hjoB-1mldA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qrp PEPSIN 3A

(Homo sapiens) 		PF00026
(Asp) 		4 VAL E 194
VAL E 214
ILE E 258
VAL E 269
 None
 0.61A 3hjoB-1qrpE:
undetectable		 3hjoB-1qrpE:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t0b THUA-LIKE PROTEIN

(Geobacillus
stearothermophilus) 		PF06283
(ThuA) 		4 VAL A  87
VAL A  79
ILE A 192
VAL A  99
 None
 0.88A 3hjoB-1t0bA:
undetectable		 3hjoB-1t0bA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tdt TETRAHYDRODIPICOLINA
TE-N-SUCCINYLTRANSFE
RASE

(Mycobacterium
bovis) 		PF00132
(Hexapep)
PF14602
(Hexapep_2)
PF14805
(THDPS_N_2) 		4 VAL A 227
VAL A 156
ASN A 181
GLY A 199
 None
 0.78A 3hjoB-1tdtA:
undetectable		 3hjoB-1tdtA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w6s METHANOL
DEHYDROGENASE
SUBUNIT 1

(Methylobacterium
extorquens) 		PF01011
(PQQ)
PF13360
(PQQ_2) 		4 VAL A 144
ILE A 171
VAL A 169
GLY A 192
 None
 0.81A 3hjoB-1w6sA:
undetectable		 3hjoB-1w6sA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x0l HOMOISOCITRATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00180
(Iso_dh) 		4 PHE A 193
VAL A 196
ILE A 168
VAL A 221
 None
 0.70A 3hjoB-1x0lA:
undetectable		 3hjoB-1x0lA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xqp 8-OXOGUANINE DNA
GLYCOSYLASE

(Pyrobaculum
aerophilum) 		PF09171
(AGOG) 		4 PHE A  76
VAL A  38
ILE A 148
GLY A  47
 None
 0.80A 3hjoB-1xqpA:
undetectable		 3hjoB-1xqpA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xqp 8-OXOGUANINE DNA
GLYCOSYLASE

(Pyrobaculum
aerophilum) 		PF09171
(AGOG) 		4 PHE A  76
VAL A  38
VAL A  81
GLY A  47
 None
 0.80A 3hjoB-1xqpA:
undetectable		 3hjoB-1xqpA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aw5 NADP-DEPENDENT MALIC
ENZYME

(Homo sapiens) 		PF00390
(malic)
PF03949
(Malic_M) 		4 PHE A 458
ILE A 485
VAL A 509
GLY A 460
 None
 0.71A 3hjoB-2aw5A:
undetectable		 3hjoB-2aw5A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ctk VIGILIN

(Homo sapiens) 		PF00013
(KH_1) 		4 PHE A  46
VAL A  48
ILE A  62
VAL A  21
 None
 0.68A 3hjoB-2ctkA:
undetectable		 3hjoB-2ctkA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfu PROBABLE
2-HYDROXYHEPTA-2,4-D
IENE-1,7-DIOATE
ISOMERASE

(Thermus
thermophilus) 		PF01557
(FAA_hydrolase)
PF10370
(DUF2437) 		4 VAL A 137
VAL A 224
VAL A 249
GLY A 139
 None
 0.87A 3hjoB-2dfuA:
undetectable		 3hjoB-2dfuA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvm 439AA LONG
HYPOTHETICAL MALATE
OXIDOREDUCTASE

(Pyrococcus
horikoshii) 		PF00390
(malic)
PF03949
(Malic_M) 		4 PHE A 332
ILE A 359
VAL A 380
GLY A 334
 None
 0.75A 3hjoB-2dvmA:
undetectable		 3hjoB-2dvmA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fqd BLUE COPPER OXIDASE
CUEO

(Escherichia
coli) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 VAL A 107
VAL A 127
ILE A 162
VAL A 160
 None
 0.86A 3hjoB-2fqdA:
undetectable		 3hjoB-2fqdA:
18.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 PHE A   8
VAL A  10
TRP A  38
ASN A 202
GLY A 203
 GTS  A 208 (-4.7A)
None
GTS  A 208 (-3.9A)
None
None
 0.21A 3hjoB-2gsrA:
35.8		 3hjoB-2gsrA:
82.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hev TUMOR NECROSIS
FACTOR LIGAND
SUPERFAMILY MEMBER 4

(Homo sapiens) 		no annotation 4 VAL F 165
VAL F 135
VAL F  64
GLY F 168
 None
 0.84A 3hjoB-2hevF:
undetectable		 3hjoB-2hevF:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iks DNA-BINDING
TRANSCRIPTIONAL DUAL
REGULATOR

(Escherichia
coli) 		PF00532
(Peripla_BP_1) 		4 VAL A 118
ILE A 144
VAL A 123
GLY A  65
 None
 0.76A 3hjoB-2iksA:
undetectable		 3hjoB-2iksA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipi ACLACINOMYCIN
OXIDOREDUCTASE
(AKNOX)

(Streptomyces
galilaeus) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		4 VAL A 175
ILE A  63
VAL A 491
GLY A 201
 None
 0.69A 3hjoB-2ipiA:
undetectable		 3hjoB-2ipiA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iut DNA TRANSLOCASE FTSK

(Pseudomonas
aeruginosa) 		PF01580
(FtsK_SpoIIIE) 		4 PHE A 350
VAL A 352
ILE A 411
VAL A 399
 None
 0.90A 3hjoB-2iutA:
undetectable		 3hjoB-2iutA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2obv S-ADENOSYLMETHIONINE
SYNTHETASE ISOFORM
TYPE-1

(Homo sapiens) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		4 TRP A 300
ILE A 332
VAL A 314
GLY A 140
 None
 0.51A 3hjoB-2obvA:
undetectable		 3hjoB-2obvA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ols PHOSPHOENOLPYRUVATE
SYNTHASE

(Neisseria
meningitidis) 		PF00391
(PEP-utilizers)
PF01326
(PPDK_N)
PF02896
(PEP-utilizers_C) 		4 VAL A   6
ILE A 120
VAL A 122
GLY A  44
 None
 0.87A 3hjoB-2olsA:
undetectable		 3hjoB-2olsA:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p0y HYPOTHETICAL PROTEIN
LP_0780

(Lactobacillus
plantarum) 		PF01933
(UPF0052) 		4 VAL A  67
ILE A 226
VAL A 193
GLY A  17
 None
 0.84A 3hjoB-2p0yA:
undetectable		 3hjoB-2p0yA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p7u CYSTEINE PROTEASE

(Trypanosoma
brucei) 		PF00112
(Peptidase_C1) 		4 VAL A  40
VAL A  13
ASN A 132
GLY A 133
 None
 0.82A 3hjoB-2p7uA:
undetectable		 3hjoB-2p7uA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2psy KALLIKREIN-5

(Homo sapiens) 		PF00089
(Trypsin) 		4 TRP A 215
ILE A 160
VAL A 138
GLY A 211
 None
 0.84A 3hjoB-2psyA:
undetectable		 3hjoB-2psyA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bzw PUTATIVE LIPASE

(Bacteroides
thetaiotaomicron) 		PF13472
(Lipase_GDSL_2) 		4 VAL A 108
ILE A 182
VAL A 113
GLY A  49
 None
 0.89A 3hjoB-3bzwA:
undetectable		 3hjoB-3bzwA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c30 AUTOINDUCER 2 SENSOR
KINASE/PHOSPHATASE
LUXQ

(Vibrio cholerae) 		PF09308
(LuxQ-periplasm) 		4 PHE A 132
ILE A 167
VAL A 165
GLY A 134
 None
 0.85A 3hjoB-3c30A:
undetectable		 3hjoB-3c30A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c4n UNCHARACTERIZED
PROTEIN DR_0571

(Deinococcus
radiodurans) 		PF01266
(DAO) 		4 VAL A 198
ILE A  42
VAL A  40
GLY A 201
 None
ADP  A 411 (-4.9A)
None
None
 0.81A 3hjoB-3c4nA:
undetectable		 3hjoB-3c4nA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cb5 FACT COMPLEX SUBUNIT
SPT16

(Schizosaccharomyces
pombe) 		PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob) 		4 VAL A 371
VAL A 353
ILE A 415
GLY A 357
 None
 0.84A 3hjoB-3cb5A:
undetectable		 3hjoB-3cb5A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cmv PROTEIN RECA

(Escherichia
coli) 		PF00154
(RecA) 		4 VAL A  37
ILE A 190
VAL A  62
GLY A  59
 None
 0.87A 3hjoB-3cmvA:
undetectable		 3hjoB-3cmvA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eg4 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-SUCCINYLTRANSFERAS
E

(Brucella suis) 		PF00132
(Hexapep)
PF14602
(Hexapep_2)
PF14805
(THDPS_N_2) 		4 VAL A 234
VAL A 163
ASN A 188
GLY A 206
 None
 0.79A 3hjoB-3eg4A:
undetectable		 3hjoB-3eg4A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC5

(Schizosaccharomyces
pombe) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L)
PF01194
(RNA_pol_N) 		4 VAL C 236
TRP C 171
ILE J   5
GLY J  11
 None
 0.57A 3hjoB-3h0gC:
undetectable		 3hjoB-3h0gC:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2t BASEPLATE STRUCTURAL
PROTEIN GP6

(Escherichia
virus T4) 		no annotation 4 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.88A 3hjoB-3h2tA:
undetectable		 3hjoB-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjp PEROXIREDOXIN,
BACTERIOFERRITIN
COMIGRATORY PROTEIN
HOMOLOG (BCP-4)

(Sulfolobus
solfataricus) 		PF00578
(AhpC-TSA) 		4 VAL A   2
VAL A 135
ILE A  11
GLY A 103
 None
 0.90A 3hjoB-3hjpA:
undetectable		 3hjoB-3hjpA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hzh CHEMOTAXIS OPERON
PROTEIN (CHEX)

(Borreliella
burgdorferi) 		PF13690
(CheX) 		4 VAL B  47
VAL B 153
ASN B  99
GLY B  98
 None
None
BFD  A  79 ( 3.2A)
None
 0.68A 3hjoB-3hzhB:
undetectable		 3hjoB-3hzhB:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iqd OCTOPINE
DEHYDROGENASE

(Pecten maximus) 		PF02317
(Octopine_DH) 		4 VAL B   7
VAL B 157
ASN B  12
GLY B  13
 None
None
NAI  B 405 (-3.7A)
NAI  B 405 (-3.5A)
 0.89A 3hjoB-3iqdB:
undetectable		 3hjoB-3iqdB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3isl PURINE CATABOLISM
PROTEIN PUCG

(Bacillus
subtilis) 		PF00266
(Aminotran_5) 		4 PHE A  99
VAL A 145
ILE A 106
GLY A 100
 PLP  A 419 (-3.5A)
None
None
None
 0.84A 3hjoB-3islA:
undetectable		 3hjoB-3islA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE

(Bacteroides
thetaiotaomicron) 		PF00809
(Pterin_bind) 		4 VAL A 594
VAL A 394
ILE A 585
GLY A 592
 None
 0.71A 3hjoB-3k13A:
undetectable		 3hjoB-3k13A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lft UNCHARACTERIZED
PROTEIN

(Streptococcus
pneumoniae) 		PF04392
(ABC_sub_bind) 		4 VAL A 235
ILE A 264
VAL A 240
GLY A 185
 None
 0.78A 3hjoB-3lftA:
undetectable		 3hjoB-3lftA:
21.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus musculus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 PHE A   8
VAL A  10
TRP A  38
ASN A 204
GLY A 205
 GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.0A)
None
GTB  A 210 (-3.7A)
 0.30A 3hjoB-3o76A:
36.6		 3hjoB-3o76A:
84.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA

(Vibrio cholerae) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 PHE B  11
VAL B  64
VAL B  42
ILE B 100
 None
 0.87A 3hjoB-3o8qB:
undetectable		 3hjoB-3o8qB:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ohp HYPOXANTHINE
PHOSPHORIBOSYLTRANSF
ERASE

(Vibrio cholerae) 		PF00156
(Pribosyltran) 		4 VAL A  14
VAL A  46
ILE A 147
VAL A 152
 None
 0.75A 3hjoB-3ohpA:
undetectable		 3hjoB-3ohpA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qt4 CATHEPSIN-L-LIKE
MIDGUT CYSTEINE
PROTEINASE

(Tenebrio
molitor) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		4 VAL A 223
VAL A 110
ILE A 303
GLY A 265
 None
 0.90A 3hjoB-3qt4A:
undetectable		 3hjoB-3qt4A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3stj PROTEASE DEGQ

(Escherichia
coli) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 VAL A 327
ILE A 244
VAL A 270
GLY A 280
 None
 0.89A 3hjoB-3stjA:
undetectable		 3hjoB-3stjA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t90 GLUCOSE-6-PHOSPHATE
ACETYLTRANSFERASE 1

(Arabidopsis
thaliana) 		PF00583
(Acetyltransf_1) 		4 PHE A 107
VAL A 104
ILE A  64
GLY A  68
 None
 0.84A 3hjoB-3t90A:
undetectable		 3hjoB-3t90A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vrh PUTATIVE
UNCHARACTERIZED
PROTEIN PH0300

(Pyrococcus
horikoshii) 		PF01171
(ATP_bind_3) 		4 VAL A  34
VAL A 204
ILE A  74
VAL A  52
 None
 0.71A 3hjoB-3vrhA:
undetectable		 3hjoB-3vrhA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wbn PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF01554
(MatE) 		4 VAL A 278
VAL A 425
ASN A 274
GLY A 275
 None
 0.86A 3hjoB-3wbnA:
1.8		 3hjoB-3wbnA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwx S12 FAMILY PEPTIDASE

(Streptomyces
sp. 82F2) 		PF00144
(Beta-lactamase) 		4 VAL A  59
VAL A  84
ASN A 358
GLY A 357
 None
 0.88A 3hjoB-3wwxA:
undetectable		 3hjoB-3wwxA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zeu PROBABLE TRNA
THREONYLCARBAMOYLADE
NOSINE BIOSYNTHESIS
PROTEIN GCP

(Salmonella
enterica) 		PF00814
(Peptidase_M22) 		4 VAL B 311
ILE B 143
VAL B 145
GLY B 149
 None
 0.73A 3hjoB-3zeuB:
undetectable		 3hjoB-3zeuB:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ccz METHIONINE SYNTHASE

(Homo sapiens) 		PF00809
(Pterin_bind)
PF02574
(S-methyl_trans) 		4 VAL A 612
VAL A 412
ILE A 603
GLY A 610
 None
 0.68A 3hjoB-4cczA:
undetectable		 3hjoB-4cczA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h44 APOCYTOCHROME F

(Nostoc sp. PCC
7120) 		PF01333
(Apocytochr_F_C)
PF16639
(Apocytochr_F_N) 		4 VAL C  34
VAL C  72
ASN C 154
GLY C 153
 None
HEM  C 301 (-4.3A)
HEM  C 301 (-4.1A)
HEM  C 301 ( 4.7A)
 0.91A 3hjoB-4h44C:
undetectable		 3hjoB-4h44C:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4imm OUTER MEMBRANE
ASSEMBLY LIPOPROTEIN
YFGL

(Moraxella
catarrhalis) 		PF13360
(PQQ_2) 		4 VAL A 184
ILE A 212
VAL A 210
GLY A 227
 None
 0.62A 3hjoB-4immA:
undetectable		 3hjoB-4immA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jcc IRON-COMPOUND ABC
TRANSPORTER,
IRON-COMPOUND-BINDIN
G PROTEIN

(Streptococcus
pneumoniae) 		PF01497
(Peripla_BP_2) 		4 PHE A 244
VAL A 247
ILE A 291
VAL A 257
 None
 0.75A 3hjoB-4jccA:
1.3		 3hjoB-4jccA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsp ENDONUCLEASE V

(Homo sapiens) 		PF04493
(Endonuclease_5) 		4 PHE A 136
VAL A  28
ASN A 128
GLY A 129
 None
 0.88A 3hjoB-4nspA:
undetectable		 3hjoB-4nspA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nsp ENDONUCLEASE V

(Homo sapiens) 		PF04493
(Endonuclease_5) 		4 PHE A 136
VAL A  28
VAL A 125
GLY A 129
 None
 0.74A 3hjoB-4nspA:
undetectable		 3hjoB-4nspA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ppz SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Neisseria
meningitidis) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 VAL A 356
ILE A 310
VAL A 367
GLY A 343
 None
 0.90A 3hjoB-4ppzA:
undetectable		 3hjoB-4ppzA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9x COPPER HOMEOSTASIS
PROTEIN CUTC

(Bacillus
anthracis) 		PF03932
(CutC) 		4 VAL A 116
ILE A 125
VAL A  99
GLY A  91
 None
 0.84A 3hjoB-4r9xA:
undetectable		 3hjoB-4r9xA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rap GLYCOSYLTRANSFERASE
TIBC

(Escherichia
coli) 		PF01075
(Glyco_transf_9) 		4 VAL A 197
ILE A 101
VAL A 167
GLY A 192
 None
 0.85A 3hjoB-4rapA:
undetectable		 3hjoB-4rapA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3m 2-DEHYDROPANTOATE
2-REDUCTASE

(Staphylococcus
aureus) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		4 VAL A 126
VAL A  53
ILE A 117
GLY A  11
 None
None
None
NAP  A 500 (-3.1A)
 0.79A 3hjoB-4s3mA:
undetectable		 3hjoB-4s3mA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wcw RIBOSOMAL SILENCING
FACTOR RSFS

(Mycobacterium
tuberculosis) 		PF02410
(RsfS) 		4 VAL A 116
ILE A  55
VAL A  59
GLY A  16
 None
 0.74A 3hjoB-4wcwA:
undetectable		 3hjoB-4wcwA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a1i S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2

(Homo sapiens) 		PF00438
(S-AdoMet_synt_N)
PF02772
(S-AdoMet_synt_M)
PF02773
(S-AdoMet_synt_C) 		4 TRP A 300
ILE A 332
VAL A 314
GLY A 140
 None
 0.50A 3hjoB-5a1iA:
undetectable		 3hjoB-5a1iA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aor DOSAGE COMPENSATION
REGULATOR

(Drosophila
melanogaster) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind) 		4 VAL A1069
ILE A1082
VAL A1092
GLY A1078
 None
 0.73A 3hjoB-5aorA:
undetectable		 3hjoB-5aorA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aoy ENDONUCLEASE V

(Mus musculus) 		PF04493
(Endonuclease_5) 		4 PHE A 136
VAL A  28
ASN A 128
GLY A 129
 None
 0.82A 3hjoB-5aoyA:
undetectable		 3hjoB-5aoyA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aoy ENDONUCLEASE V

(Mus musculus) 		PF04493
(Endonuclease_5) 		4 PHE A 136
VAL A  28
VAL A 125
GLY A 129
 None
 0.72A 3hjoB-5aoyA:
undetectable		 3hjoB-5aoyA:
23.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d73 GLUTATHIONE
S-TRANSFERASE

(Wuchereria
bancrofti) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 PHE A   8
TRP A  38
ASN A 203
GLY A 204
 GSH  A 301 (-4.9A)
GSH  A 301 (-4.0A)
None
None
 0.36A 3hjoB-5d73A:
30.6		 3hjoB-5d73A:
41.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gje LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6

(Homo sapiens) 		PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition) 		4 VAL A 433
ILE A 516
ASN A 474
GLY A 475
 None
 0.72A 3hjoB-5gjeA:
undetectable		 3hjoB-5gjeA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ham RICKCE

(Rickettsia
bellii) 		no annotation 4 VAL A 566
VAL A 446
ASN A 635
GLY A 636
 None
 0.89A 3hjoB-5hamA:
undetectable		 3hjoB-5hamA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i33 ADENYLOSUCCINATE
SYNTHETASE

(Cryptococcus
neoformans) 		PF00709
(Adenylsucc_synt) 		4 VAL A  25
ILE A 250
VAL A 253
GLY A 227
 None
 0.80A 3hjoB-5i33A:
undetectable		 3hjoB-5i33A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i84 PHOSPHATE-BINDING
PROTEIN PSTS

(Xanthomonas
citri) 		PF12849
(PBP_like_2) 		4 PHE A  76
VAL A 286
VAL A  28
ILE A 330
 None
 0.76A 3hjoB-5i84A:
undetectable		 3hjoB-5i84A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 VAL A 102
TRP A 139
ILE A 128
GLY A 223
 None
 0.89A 3hjoB-5ip9A:
undetectable		 3hjoB-5ip9A:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j0a LYMPHOKINE-ACTIVATED
KILLER
T-CELL-ORIGINATED
PROTEIN KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A 199
ILE A 184
VAL A 187
GLY A 166
 None
 0.88A 3hjoB-5j0aA:
undetectable		 3hjoB-5j0aA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2d SURFACE-ASSOCIATED
PROTEIN CSHA

(Streptococcus
gordonii) 		no annotation 4 VAL A 180
ILE A 154
VAL A 224
GLY A 218
 None
 0.68A 3hjoB-5l2dA:
undetectable		 3hjoB-5l2dA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lf5 MYELIN-ASSOCIATED
GLYCOPROTEIN

(Mus musculus) 		PF08205
(C2-set_2)
PF13927
(Ig_3) 		4 PHE A  61
VAL A  73
ILE A  40
VAL A  38
 None
 0.65A 3hjoB-5lf5A:
undetectable		 3hjoB-5lf5A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lfr MYELIN-ASSOCIATED
GLYCOPROTEIN

(Mus musculus) 		PF08205
(C2-set_2)
PF13927
(Ig_3) 		4 PHE A  61
VAL A  73
ILE A  40
VAL A  38
 None
 0.68A 3hjoB-5lfrA:
undetectable		 3hjoB-5lfrA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqp GLYCOSIDE HYDROLASE
BT_1002

(Bacteroides
thetaiotaomicron) 		no annotation 4 VAL A 402
VAL A 301
ILE A 450
VAL A 407
 None
 0.90A 3hjoB-5mqpA:
undetectable		 3hjoB-5mqpA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqs BETA-L-ARABINOBIOSID
ASE

(Bacteroides
thetaiotaomicron) 		PF13088
(BNR_2) 		4 VAL A 189
VAL A 123
ASN A 169
GLY A 168
 None
 0.86A 3hjoB-5mqsA:
2.0		 3hjoB-5mqsA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u03 CTP SYNTHASE 1

(Homo sapiens) 		PF00117
(GATase)
PF06418
(CTP_synth_N) 		4 VAL A 262
VAL A 253
ILE A   4
VAL A   6
 None
 0.79A 3hjoB-5u03A:
undetectable		 3hjoB-5u03A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v4b F-BOX/WD
REPEAT-CONTAINING
PROTEIN 7

(Homo sapiens) 		PF00400
(WD40)
PF12937
(F-box-like) 		4 VAL B2627
VAL B2637
ASN B2598
GLY B2597
 None
 0.80A 3hjoB-5v4bB:
undetectable		 3hjoB-5v4bB:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vug UNCHARACTERIZED
PROTEIN RV2277C

(Mycobacterium
tuberculosis) 		PF03009
(GDPD) 		4 VAL A 248
VAL A  11
ILE A 260
GLY A 245
 None
 0.90A 3hjoB-5vugA:
undetectable		 3hjoB-5vugA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x2q TASTE RECEPTOR, TYPE
1, MEMBER 2A

(Oryzias latipes) 		PF01094
(ANF_receptor) 		4 PHE A 178
VAL A 160
ASN A 423
GLY A 424
 None
None
None
NA  A 962 ( 4.6A)
 0.66A 3hjoB-5x2qA:
undetectable		 3hjoB-5x2qA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x9y DNA MISMATCH REPAIR
PROTEIN MUTL

(Aquifex
aeolicus) 		no annotation 4 PHE C 108
VAL C 133
ASN C  52
GLY C  53
 None
 0.86A 3hjoB-5x9yC:
undetectable		 3hjoB-5x9yC:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmd EPOXIDE HYDROLASE A

(Vigna radiata) 		no annotation 4 VAL A 253
ILE A  76
VAL A  80
GLY A 107
 None
 0.73A 3hjoB-5xmdA:
undetectable		 3hjoB-5xmdA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT

(Komagataella
phaffii) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 VAL A 102
TRP A 139
ILE A 128
GLY A 224
 None
 0.76A 3hjoB-5xogA:
undetectable		 3hjoB-5xogA:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xoy [LYSW]-LYSINE
HYDROLASE

(Thermus
thermophilus) 		PF01546
(Peptidase_M20) 		4 VAL A 332
ILE A 285
VAL A 343
GLY A 318
 None
 0.83A 3hjoB-5xoyA:
undetectable		 3hjoB-5xoyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xu1 ABC TRANSPORTER
PERMEAE

(Streptococcus
pneumoniae) 		no annotation 4 VAL M 144
ILE M 234
ASN M 222
GLY M 136
 None
 0.81A 3hjoB-5xu1M:
undetectable		 3hjoB-5xu1M:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6amz 2,3,4,5-TETRAHYDROPY
RIDINE-2,6-DICARBOXY
LATE
N-SUCCINYLTRANSFERAS
E

(Acinetobacter
baumannii) 		PF00132
(Hexapep)
PF14602
(Hexapep_2)
PF14805
(THDPS_N_2) 		4 VAL A 227
VAL A 156
ASN A 181
GLY A 199
 None
 0.73A 3hjoB-6amzA:
undetectable		 3hjoB-6amzA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6aon DIHYDROLIPOYL
DEHYDROGENASE

(Bordetella
pertussis) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 VAL A 273
ILE A 170
VAL A 278
GLY A 187
 None
 0.71A 3hjoB-6aonA:
undetectable		 3hjoB-6aonA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b3r PIEZO-TYPE
MECHANOSENSITIVE ION
CHANNEL COMPONENT 1

(Mus musculus) 		no annotation 4 VAL A1701
ILE A1694
VAL A1788
ASN A1698
 None
 0.89A 3hjoB-6b3rA:
undetectable		 3hjoB-6b3rA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b5v TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5

(Oryctolagus
cuniculus) 		no annotation 4 VAL A 143
VAL A 125
ILE A 189
VAL A 199
 None
 0.87A 3hjoB-6b5vA:
undetectable		 3hjoB-6b5vA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c2h CYSTATHIONINE
BETA-SYNTHASE

(Saccharomyces
cerevisiae) 		no annotation 4 VAL A 115
ILE A  52
ASN A  47
GLY A  49
 None
 0.85A 3hjoB-6c2hA:
undetectable		 3hjoB-6c2hA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cqb CHALCONE SYNTHASE

(Piper
methysticum) 		no annotation 4 PHE A 374
VAL A 380
VAL A 303
ASN A 279
 None
 0.77A 3hjoB-6cqbA:
undetectable		 3hjoB-6cqbA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fkh ATP SYNTHASE GAMMA
CHAIN, CHLOROPLASTIC

(Spinacia
oleracea) 		no annotation 4 VAL g 226
VAL g 218
ILE g 239
VAL g 247
 None
 0.86A 3hjoB-6fkhg:
undetectable		 3hjoB-6fkhg:
15.84