SIMILAR PATTERNS OF AMINO ACIDS FOR 3HJO_A_EAAA211

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b25 PROTEIN
(FORMALDEHYDE
FERREDOXIN
OXIDOREDUCTASE)

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 PHE A  31
VAL A 529
ILE A   8
GLY A  33
 None
 0.82A 3hjoA-1b25A:
undetectable		 3hjoA-1b25A:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kgp RIBONUCLEOTIDE
REDUCTASE PROTEIN
R2F

(Corynebacterium
ammoniagenes) 		PF00268
(Ribonuc_red_sm) 		4 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.79A 3hjoA-1kgpA:
undetectable		 3hjoA-1kgpA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kh2 ARGININOSUCCINATE
SYNTHETASE

(Thermus
thermophilus) 		PF00764
(Arginosuc_synth) 		4 TYR A 279
VAL A  79
VAL A 254
GLY A  82
 None
 0.89A 3hjoA-1kh2A:
undetectable		 3hjoA-1kh2A:
22.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		6 TYR A   7
PHE A   8
VAL A  10
VAL A  35
TRP A  38
GLN A  39
 None
GSH  A 504 (-4.7A)
None
None
GSH  A 504 (-3.9A)
None
 0.20A 3hjoA-1lbkA:
36.1		 3hjoA-1lbkA:
96.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		6 TYR A   7
PHE A   8
VAL A  10
VAL A  35
TRP A  38
ILE A 104
 None
GSH  A 504 (-4.7A)
None
None
GSH  A 504 (-3.9A)
None
 0.54A 3hjoA-1lbkA:
36.1		 3hjoA-1lbkA:
96.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0u GST2 GENE PRODUCT

(Drosophila
melanogaster) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A  54
PHE A  55
VAL A  57
TRP A  85
 GSH  A 500 (-4.7A)
GSH  A 500 (-4.8A)
None
GSH  A 500 (-3.6A)
 0.49A 3hjoA-1m0uA:
23.0		 3hjoA-1m0uA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q7l AMINOACYLASE-1

(Homo sapiens) 		PF01546
(Peptidase_M20) 		4 PHE A 158
VAL A  54
VAL A 159
GLY A 154
 None
 0.91A 3hjoA-1q7lA:
undetectable		 3hjoA-1q7lA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r7l PHAGE PROTEIN

(Bacillus cereus) 		no annotation 4 VAL A  79
VAL A  57
ILE A   6
GLY A  91
 None
 0.90A 3hjoA-1r7lA:
undetectable		 3hjoA-1r7lA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sgf NERVE GROWTH FACTOR

(Mus musculus) 		PF00089
(Trypsin) 		4 TYR G  40
VAL G  66
TRP G  67
GLY G  44
 None
 0.70A 3hjoA-1sgfG:
undetectable		 3hjoA-1sgfG:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sky F1-ATPASE

(Bacillus sp.
PS3) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 VAL E 184
VAL E  87
ILE E 292
GLY E 232
 None
 0.95A 3hjoA-1skyE:
undetectable		 3hjoA-1skyE:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uzr RIBONUCLEOTIDE
REDUCTASE R2-2 SMALL
SUBUNIT

(Mycobacterium
tuberculosis) 		PF00268
(Ribonuc_red_sm) 		4 TYR A 110
PHE A  65
ILE A 194
GLY A 170
 None
 0.85A 3hjoA-1uzrA:
undetectable		 3hjoA-1uzrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vbr ENDO-1,4-BETA-XYLANA
SE B

(Thermotoga
maritima) 		PF00331
(Glyco_hydro_10) 		4 VAL A 639
VAL A 631
ILE A 686
GLY A 597
 None
 0.92A 3hjoA-1vbrA:
undetectable		 3hjoA-1vbrA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xqp 8-OXOGUANINE DNA
GLYCOSYLASE

(Pyrobaculum
aerophilum) 		PF09171
(AGOG) 		4 PHE A  76
VAL A  38
ILE A 148
GLY A  47
 None
 0.82A 3hjoA-1xqpA:
undetectable		 3hjoA-1xqpA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xqp 8-OXOGUANINE DNA
GLYCOSYLASE

(Pyrobaculum
aerophilum) 		PF09171
(AGOG) 		4 PHE A  76
VAL A  38
VAL A  81
GLY A  47
 None
 0.81A 3hjoA-1xqpA:
undetectable		 3hjoA-1xqpA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zem XYLITOL
DEHYDROGENASE

(Gluconobacter
oxydans) 		PF13561
(adh_short_C2) 		4 TYR A 157
VAL A 148
ILE A  19
GLY A 188
 NAD  A2263 (-4.4A)
None
NAD  A2263 (-3.8A)
None
 0.73A 3hjoA-1zemA:
undetectable		 3hjoA-1zemA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zj9 PROBABLE
FERREDOXIN-DEPENDENT
NITRITE REDUCTASE
NIRA

(Mycobacterium
tuberculosis) 		PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		4 VAL A 546
GLN A 494
ILE A 456
GLY A 498
 None
 0.53A 3hjoA-1zj9A:
undetectable		 3hjoA-1zj9A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ag5 DEHYDROGENASE/REDUCT
ASE (SDR FAMILY)
MEMBER 6

(Homo sapiens) 		PF13561
(adh_short_C2) 		4 TYR A 147
VAL A 138
ILE A  18
GLY A 178
 NAD  A2001 (-4.6A)
None
NAD  A2001 (-3.5A)
None
 0.80A 3hjoA-2ag5A:
undetectable		 3hjoA-2ag5A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1q LUCIFERIN
4-MONOOXYGENASE

(Luciola
cruciata) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 PHE A 371
VAL A 367
ILE A  10
GLY A  13
 None
 0.95A 3hjoA-2d1qA:
undetectable		 3hjoA-2d1qA:
16.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 TYR A   7
PHE A   8
VAL A  10
TRP A  38
GLY A 203
 GTS  A 208 (-4.5A)
GTS  A 208 (-4.7A)
None
GTS  A 208 (-3.9A)
None
 0.20A 3hjoA-2gsrA:
35.8		 3hjoA-2gsrA:
82.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnl GLUTATHIONE
S-TRANSFERASE 1

(Onchocerca
volvulus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A  32
PHE A  33
TRP A  63
ILE A 127
 None
None
GSH  A 501 (-3.9A)
None
 0.52A 3hjoA-2hnlA:
25.5		 3hjoA-2hnlA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2huf ALANINE GLYOXYLATE
AMINOTRANSFERASE

(Aedes aegypti) 		PF00266
(Aminotran_5) 		4 TYR A 307
VAL A 354
VAL A 317
GLY A 346
 None
 0.84A 3hjoA-2hufA:
undetectable		 3hjoA-2hufA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i44 SERINE-THREONINE
PHOSPHATASE 2C

(Toxoplasma
gondii) 		PF00481
(PP2C) 		4 TYR A 124
VAL A  83
ILE A 167
GLY A  64
 None
 0.94A 3hjoA-2i44A:
undetectable		 3hjoA-2i44A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2il5 HYPOTHETICAL PROTEIN

(Staphylococcus
aureus) 		PF08327
(AHSA1) 		4 TYR A  78
VAL A  54
TRP A  30
ILE A  50
 None
 0.96A 3hjoA-2il5A:
undetectable		 3hjoA-2il5A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jhq URACIL
DNA-GLYCOSYLASE

(Vibrio cholerae) 		PF03167
(UDG) 		4 TYR A  66
VAL A  79
ILE A  92
GLY A 109
 None
 0.96A 3hjoA-2jhqA:
undetectable		 3hjoA-2jhqA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2msk NITROGEN REGULATION
PROTEIN NR(I)

(Salmonella
enterica) 		PF00072
(Response_reg) 		4 PHE A  33
VAL A   9
ILE A  69
GLY A  36
 None
 0.95A 3hjoA-2mskA:
undetectable		 3hjoA-2mskA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oq5 TRANSMEMBRANE
PROTEASE, SERINE 11E

(Homo sapiens) 		PF00089
(Trypsin) 		4 VAL A 231
TRP A  29
GLN A  30
ILE A 244
 None
 0.86A 3hjoA-2oq5A:
undetectable		 3hjoA-2oq5A:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qe7 ATP SYNTHASE SUBUNIT
BETA

(Bacillus sp.
TA2.A1) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 VAL D 177
VAL D  81
ILE D 285
GLY D 225
 None
 0.93A 3hjoA-2qe7D:
undetectable		 3hjoA-2qe7D:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vid SERINE PROTEASE SPLB

(Staphylococcus
aureus) 		PF00089
(Trypsin) 		4 TYR A 106
PHE A 190
VAL A 188
ILE A 202
 None
 0.86A 3hjoA-2vidA:
undetectable		 3hjoA-2vidA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wgh RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE SUBUNIT

(Homo sapiens) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC) 		4 TYR A 279
PHE A 297
GLN A 288
GLY A 249
 None
 0.95A 3hjoA-2wghA:
undetectable		 3hjoA-2wghA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtg GLOBIN-LIKE PROTEIN

(Caenorhabditis
elegans) 		PF00042
(Globin) 		4 PHE A  90
VAL A  83
ILE A  98
GLY A  92
 None
 0.95A 3hjoA-2wtgA:
undetectable		 3hjoA-2wtgA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xyd ANGIOTENSIN-CONVERTI
NG ENZYME

(Homo sapiens) 		PF01401
(Peptidase_M2) 		4 PHE A  20
GLN A  25
ILE A  79
GLY A  16
 None
 0.96A 3hjoA-2xydA:
undetectable		 3hjoA-2xydA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cb5 FACT COMPLEX SUBUNIT
SPT16

(Schizosaccharomyces
pombe) 		PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob) 		4 VAL A 371
VAL A 353
ILE A 415
GLY A 357
 None
 0.83A 3hjoA-3cb5A:
undetectable		 3hjoA-3cb5A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cr3 PTS-DEPENDENT
DIHYDROXYACETONE
KINASE,
PHOSPHOTRANSFERASE
SUBUNIT DHAM

(Lactococcus
lactis) 		PF03610
(EIIA-man) 		4 PHE C  88
VAL C  90
ILE C   7
GLY C  95
 None
 0.95A 3hjoA-3cr3C:
undetectable		 3hjoA-3cr3C:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxm URACIL-DNA
GLYCOSYLASE

(Leishmania
naiffi) 		PF03167
(UDG) 		4 TYR A 208
VAL A 221
ILE A 234
GLY A 251
 URB  A 401 ( 3.3A)
None
None
None
 0.95A 3hjoA-3cxmA:
undetectable		 3hjoA-3cxmA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6b GLUTARYL-COA
DEHYDROGENASE

(Burkholderia
pseudomallei) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 TYR A 373
VAL A 369
ILE A 210
GLY A 215
 None
 0.79A 3hjoA-3d6bA:
2.1		 3hjoA-3d6bA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB3
DNA-DIRECTED RNA
POLYMERASES I, II,
AND III SUBUNIT
RPABC5

(Schizosaccharomyces
pombe) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L)
PF01194
(RNA_pol_N) 		4 VAL C 236
TRP C 171
ILE J   5
GLY J  11
 None
 0.58A 3hjoA-3h0gC:
undetectable		 3hjoA-3h0gC:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2t BASEPLATE STRUCTURAL
PROTEIN GP6

(Escherichia
virus T4) 		no annotation 4 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.89A 3hjoA-3h2tA:
undetectable		 3hjoA-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igx TRANSALDOLASE

(Francisella
tularensis) 		PF00923
(TAL_FSA) 		4 TYR A 217
PHE A 222
ILE A 143
GLY A 174
 None
 0.67A 3hjoA-3igxA:
undetectable		 3hjoA-3igxA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3isl PURINE CATABOLISM
PROTEIN PUCG

(Bacillus
subtilis) 		PF00266
(Aminotran_5) 		4 PHE A  99
VAL A 145
ILE A 106
GLY A 100
 PLP  A 419 (-3.5A)
None
None
None
 0.84A 3hjoA-3islA:
undetectable		 3hjoA-3islA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k13 5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE

(Bacteroides
thetaiotaomicron) 		PF00809
(Pterin_bind) 		4 VAL A 594
VAL A 394
ILE A 585
GLY A 592
 None
 0.72A 3hjoA-3k13A:
undetectable		 3hjoA-3k13A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m16 TRANSALDOLASE

(Oleispira
antarctica) 		PF00923
(TAL_FSA) 		4 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.77A 3hjoA-3m16A:
undetectable		 3hjoA-3m16A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mg3 ORANGE
CAROTENOID-BINDING
PROTEIN

(Synechocystis
sp. PCC 6803) 		PF02136
(NTF2)
PF09150
(Carot_N) 		4 TYR A  98
PHE A 109
GLN A  72
GLY A 108
 None
 0.82A 3hjoA-3mg3A:
undetectable		 3hjoA-3mg3A:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o3r ALDO-KETO REDUCTASE
FAMILY 1, MEMBER B7

(Rattus
norvegicus) 		PF00248
(Aldo_ket_red) 		4 VAL A 265
GLN A  27
ILE A  75
GLY A  19
 NAP  A 317 (-3.8A)
None
None
NAP  A 317 (-3.2A)
 0.86A 3hjoA-3o3rA:
undetectable		 3hjoA-3o3rA:
23.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus musculus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 TYR A   7
PHE A   8
VAL A  10
TRP A  38
GLY A 205
 None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.0A)
GTB  A 210 (-3.7A)
 0.19A 3hjoA-3o76A:
36.6		 3hjoA-3o76A:
84.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o8q SHIKIMATE
5-DEHYDROGENASE I
ALPHA

(Vibrio cholerae) 		PF01488
(Shikimate_DH)
PF08501
(Shikimate_dh_N) 		4 PHE B  11
VAL B  64
VAL B  42
ILE B 100
 None
 0.85A 3hjoA-3o8qB:
undetectable		 3hjoA-3o8qB:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q3q ALKALINE PHOSPHATASE

(Sphingomonas
sp. BSAR-1) 		PF01663
(Phosphodiest) 		4 VAL A 488
VAL A 238
ILE A 262
GLY A 307
 None
 0.95A 3hjoA-3q3qA:
undetectable		 3hjoA-3q3qA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qt4 CATHEPSIN-L-LIKE
MIDGUT CYSTEINE
PROTEINASE

(Tenebrio
molitor) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		4 VAL A 223
VAL A 110
ILE A 303
GLY A 265
 None
 0.89A 3hjoA-3qt4A:
undetectable		 3hjoA-3qt4A:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rjt LIPOLYTIC PROTEIN
G-D-S-L FAMILY

(Alicyclobacillus
acidocaldarius) 		PF13472
(Lipase_GDSL_2) 		4 TYR A  36
VAL A  56
ILE A  88
GLY A  59
 None
 0.96A 3hjoA-3rjtA:
undetectable		 3hjoA-3rjtA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t90 GLUCOSE-6-PHOSPHATE
ACETYLTRANSFERASE 1

(Arabidopsis
thaliana) 		PF00583
(Acetyltransf_1) 		4 PHE A 107
VAL A 104
ILE A  64
GLY A  68
 None
 0.84A 3hjoA-3t90A:
undetectable		 3hjoA-3t90A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tbj ACTIBIND

(Aspergillus
niger) 		PF00445
(Ribonuclease_T2) 		4 TYR A 237
VAL A 228
ILE A 145
GLY A 230
 None
 0.85A 3hjoA-3tbjA:
undetectable		 3hjoA-3tbjA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr7 URACIL-DNA
GLYCOSYLASE

(Coxiella
burnetii) 		PF03167
(UDG) 		4 TYR A  69
VAL A  82
ILE A  95
GLY A 111
 None
 0.91A 3hjoA-3tr7A:
undetectable		 3hjoA-3tr7A:
22.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3vpq GLUTATHIONE
S-TRANSFERASE SIGMA

(Bombyx mori) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   8
PHE A   9
VAL A  11
TRP A  39
 GSH  A 301 (-4.3A)
GSH  A 301 (-4.3A)
None
GSH  A 301 (-3.5A)
 0.30A 3hjoA-3vpqA:
20.6		 3hjoA-3vpqA:
31.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zoq URACIL-DNA
GLYCOSYLASE

(Bacillus
subtilis) 		PF03167
(UDG) 		4 TYR A  67
VAL A  80
ILE A  93
GLY A 109
 None
 0.96A 3hjoA-3zoqA:
undetectable		 3hjoA-3zoqA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aej COLLAGEN
ALPHA-1(III) CHAIN

(Homo sapiens) 		PF01410
(COLFI) 		4 VAL A 242
VAL A 221
GLN A 116
ILE A  69
 None
 0.90A 3hjoA-4aejA:
undetectable		 3hjoA-4aejA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ccz METHIONINE SYNTHASE

(Homo sapiens) 		PF00809
(Pterin_bind)
PF02574
(S-methyl_trans) 		4 VAL A 612
VAL A 412
ILE A 603
GLY A 610
 None
 0.68A 3hjoA-4cczA:
undetectable		 3hjoA-4cczA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d1d HYDANTOIN TRANSPORT
PROTEIN

(Microbacterium
liquefaciens) 		PF02133
(Transp_cyt_pur) 		4 PHE A 269
VAL A  58
ILE A 287
GLY A 271
 None
 0.95A 3hjoA-4d1dA:
undetectable		 3hjoA-4d1dA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fno PEPTIDYL-TRNA
HYDROLASE

(Pseudomonas
aeruginosa) 		PF01195
(Pept_tRNA_hydro) 		4 VAL A  38
GLN A   5
ILE A  64
GLY A  51
 None
None
GOL  A 203 (-4.5A)
None
 0.83A 3hjoA-4fnoA:
undetectable		 3hjoA-4fnoA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hst GLUTARYL-7-AMINOCEPH
ALOSPORANIC ACID
ACYLASE BETA CHAIN

(Pseudomonas) 		PF01804
(Penicil_amidase) 		4 TYR B  32
PHE B  31
VAL B  49
ILE B 176
 GLJ  B 601 (-4.9A)
None
None
None
 0.79A 3hjoA-4hstB:
undetectable		 3hjoA-4hstB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iiv 3-OXOACYL-[ACYL-CARR
IER PROTEIN]
REDUCTASE

(Escherichia
coli) 		PF13561
(adh_short_C2) 		4 TYR A 153
VAL A 144
ILE A  14
GLY A 184
 NAP  A1901 (-4.6A)
None
NAP  A1901 (-4.0A)
NAP  A1901 (-4.9A)
 0.84A 3hjoA-4iivA:
undetectable		 3hjoA-4iivA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jmh CLAMP SHC1_PY239/240

(synthetic
construct) 		PF00017
(SH2)
PF00041
(fn3) 		4 PHE A  63
VAL A  79
TRP A  40
GLY A  61
 None
 0.94A 3hjoA-4jmhA:
undetectable		 3hjoA-4jmhA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mbo SERINE-RICH REPEAT
ADHESION
GLYCOPROTEIN (SRR1)

(Streptococcus
agalactiae) 		PF10425
(SdrG_C_C) 		4 TYR A 569
VAL A 565
VAL A 594
GLN A 501
 None
 0.85A 3hjoA-4mboA:
undetectable		 3hjoA-4mboA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q4l ATP SYNTHASE SUBUNIT
BETA 1

(Burkholderia
thailandensis) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 VAL A 192
VAL A  96
ILE A 299
GLY A 240
 None
 0.94A 3hjoA-4q4lA:
undetectable		 3hjoA-4q4lA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qav 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
SYNTHASE 2

(Neisseria
meningitidis) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		4 VAL A 348
GLN A  13
ILE A 141
GLY A 343
 None
 0.87A 3hjoA-4qavA:
undetectable		 3hjoA-4qavA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rmb SERINE RICH REPEAT
PROTEIN-1 (SRR-1)

(Streptococcus
agalactiae) 		PF10425
(SdrG_C_C) 		4 TYR A 569
VAL A 565
VAL A 594
GLN A 501
 None
 0.80A 3hjoA-4rmbA:
undetectable		 3hjoA-4rmbA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s3m 2-DEHYDROPANTOATE
2-REDUCTASE

(Staphylococcus
aureus) 		PF02558
(ApbA)
PF08546
(ApbA_C) 		5 TYR A  40
VAL A 126
VAL A  53
ILE A 117
GLY A  11
 None
None
None
None
NAP  A 500 (-3.1A)
 0.90A 3hjoA-4s3mA:
undetectable		 3hjoA-4s3mA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u6d CONSERVED
HYPOTHETICAL
PERIPLASMIC PROTEIN

(Zobellia
galactanivorans) 		no annotation 4 TYR A 180
VAL A 164
VAL A 149
TRP A 208
 None
 0.83A 3hjoA-4u6dA:
undetectable		 3hjoA-4u6dA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4udn PERIPLASMIC SOLUTE
BINDING PROTEIN

(Candidatus
Liberibacter
asiaticus) 		PF01297
(ZnuA) 		4 TYR A 177
VAL A 176
VAL A 246
GLY A 173
 None
 0.92A 3hjoA-4udnA:
undetectable		 3hjoA-4udnA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w66 GLUTATHIONE
S-TRANSFERASE DOMAIN
PROTEIN

(Haliangium
ochraceum) 		PF14497
(GST_C_3) 		4 TYR A   9
PHE A  10
VAL A  12
TRP A  40
 None
 0.36A 3hjoA-4w66A:
21.5		 3hjoA-4w66A:
27.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w82 FATTY ACID SYNTHASE

(Homo sapiens) 		PF00107
(ADH_zinc_N) 		4 PHE A1831
VAL A1854
ILE A1544
GLY A1833
 None
 0.93A 3hjoA-4w82A:
undetectable		 3hjoA-4w82A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xb4 ORANGE
CAROTENOID-BINDING
PROTEIN

(Synechocystis
sp. PCC 6803) 		PF09150
(Carot_N) 		4 TYR A  98
GLN A  72
ILE A  40
GLY A 108
 None
None
45D  A 201 (-3.5A)
45D  A 201 ( 4.4A)
 0.86A 3hjoA-4xb4A:
undetectable		 3hjoA-4xb4A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xkz VALINE-TRNA LIGASE

(Pseudomonas
aeruginosa) 		PF08264
(Anticodon_1) 		4 VAL A 665
GLN A 767
ILE A 675
GLY A 733
 None
None
IOD  A 902 ( 4.3A)
None
 0.82A 3hjoA-4xkzA:
3.6		 3hjoA-4xkzA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 ANAPHASE-PROMOTING
COMPLEX SUBUNIT 5

(Homo sapiens) 		PF12862
(ANAPC5) 		4 VAL O 713
GLN O 717
ILE O 648
GLY O 661
 None
 0.77A 3hjoA-5a31O:
3.1		 3hjoA-5a31O:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdf ATP SYNTHASE SUBUNIT
BETA

(Paracoccus
denitrificans) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 VAL E 214
VAL E 251
ILE E  77
GLY E 232
 None
 0.96A 3hjoA-5cdfE:
undetectable		 3hjoA-5cdfE:
19.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d73 GLUTATHIONE
S-TRANSFERASE

(Wuchereria
bancrofti) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
PHE A   8
TRP A  38
GLY A 204
 None
GSH  A 301 (-4.9A)
GSH  A 301 (-4.0A)
None
 0.25A 3hjoA-5d73A:
30.6		 3hjoA-5d73A:
41.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ev7 CONSERVED DOMAIN
PROTEIN

(Bacillus
anthracis) 		PF13402
(Peptidase_M60)
PF17291
(M60-like_N) 		4 VAL A 348
TRP A 351
GLN A 352
GLY A 323
 None
 0.68A 3hjoA-5ev7A:
undetectable		 3hjoA-5ev7A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewo STRUCTURAL PROTEIN

(Mamastrovirus 1) 		PF12226
(Astro_capsid_p) 		4 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.93A 3hjoA-5ewoA:
undetectable		 3hjoA-5ewoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fl7 ATP SYNTHASE SUBUNIT
BETA

(Yarrowia
lipolytica) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 VAL D 214
VAL D 118
ILE D 327
GLY D 267
 None
 0.95A 3hjoA-5fl7D:
undetectable		 3hjoA-5fl7D:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae) 		PF12717
(Cnd1) 		4 TYR A 157
VAL A 219
ILE A 179
GLY A 172
 None
 0.90A 3hjoA-5frsA:
2.2		 3hjoA-5frsA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i84 PHOSPHATE-BINDING
PROTEIN PSTS

(Xanthomonas
citri) 		PF12849
(PBP_like_2) 		4 PHE A  76
VAL A 286
VAL A  28
ILE A 330
 None
 0.74A 3hjoA-5i84A:
undetectable		 3hjoA-5i84A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 VAL A 102
TRP A 139
ILE A 128
GLY A 223
 None
 0.88A 3hjoA-5ip9A:
undetectable		 3hjoA-5ip9A:
8.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jif HEMAGGLUTININ-ESTERA
SE

(Murine
coronavirus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		4 PHE A 182
VAL A 163
GLN A 230
GLY A 184
 None
None
NA  A 801 (-3.5A)
None
 0.95A 3hjoA-5jifA:
undetectable		 3hjoA-5jifA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k9z PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE

(Paraburkholderia
xenovorans) 		PF13561
(adh_short_C2) 		4 TYR A 161
VAL A 152
ILE A  27
GLY A 192
 None
 0.82A 3hjoA-5k9zA:
undetectable		 3hjoA-5k9zA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kf7 BIFUNCTIONAL PROTEIN
PUTA

(Sinorhizobium
meliloti) 		PF00171
(Aldedh)
PF01619
(Pro_dh)
PF14850
(Pro_dh-DNA_bdg) 		4 VAL A 461
VAL A 441
ILE A 472
GLY A 215
 None
 0.92A 3hjoA-5kf7A:
undetectable		 3hjoA-5kf7A:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5koh NITROGENASE FEMO
BETA SUBUNIT PROTEIN
NIFK

(Gluconacetobacter
diazotrophicus) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		4 TYR B 196
PHE B  76
ILE B 249
GLY B  80
 None
 0.82A 3hjoA-5kohB:
undetectable		 3hjoA-5kohB:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nof ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE

(Thermococcus
kodakarensis) 		no annotation 4 PHE A 168
VAL A 105
VAL A 167
GLY A 172
 None
 0.93A 3hjoA-5nofA:
undetectable		 3hjoA-5nofA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uf2 RIBOSE-5-PHOSPHATE
ISOMERASE A

(Neisseria
gonorrhoeae) 		PF06026
(Rib_5-P_isom_A) 		4 VAL A 107
VAL A  69
ILE A  33
GLY A  26
 None
 0.95A 3hjoA-5uf2A:
undetectable		 3hjoA-5uf2A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vug UNCHARACTERIZED
PROTEIN RV2277C

(Mycobacterium
tuberculosis) 		PF03009
(GDPD) 		4 VAL A 248
VAL A  11
ILE A 260
GLY A 245
 None
 0.92A 3hjoA-5vugA:
undetectable		 3hjoA-5vugA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w15 ALPHA/BETA HYDROLASE
FOLD PROTEIN

(Burkholderia
ambifaria) 		PF12697
(Abhydrolase_6) 		4 TYR A  55
VAL A  29
GLN A 191
GLY A  99
 None
 0.74A 3hjoA-5w15A:
undetectable		 3hjoA-5w15A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x55 PROBABLE URACIL-DNA
GLYCOSYLASE

(Acanthamoeba
polyphaga
mimivirus) 		PF03167
(UDG) 		4 TYR A 193
VAL A 211
ILE A 224
GLY A 241
 None
 0.86A 3hjoA-5x55A:
undetectable		 3hjoA-5x55A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xau LAMININ SUBUNIT
ALPHA-5

(Homo sapiens) 		PF02210
(Laminin_G_2)
PF06009
(Laminin_II) 		4 VAL A3087
VAL A3111
ILE A3027
GLY A3066
 None
 0.95A 3hjoA-5xauA:
undetectable		 3hjoA-5xauA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT

(Komagataella
phaffii) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 VAL A 102
TRP A 139
ILE A 128
GLY A 224
 None
 0.77A 3hjoA-5xogA:
undetectable		 3hjoA-5xogA:
7.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwb 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Colwellia
psychrerythraea) 		PF00275
(EPSP_synthase) 		4 PHE A 250
VAL A 261
ILE A   9
GLY A 254
 None
 0.92A 3hjoA-5xwbA:
undetectable		 3hjoA-5xwbA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xww AMPHB

(Streptomyces
nodosus) 		no annotation 4 TYR A 367
VAL A 358
ILE A 230
GLY A 394
 NAP  A 501 ( 4.5A)
None
NAP  A 501 (-3.9A)
NAP  A 501 (-4.9A)
 0.74A 3hjoA-5xwwA:
undetectable		 3hjoA-5xwwA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi 40S RIBOSOMAL
PROTEIN S5-B,
PUTATIVE
UNCHARACTERIZED
PROTEIN

(Trichomonas
vaginalis) 		PF00177
(Ribosomal_S7)
PF03297
(Ribosomal_S25) 		4 TYR F  10
PHE F   7
VAL F  38
ILE Z  77
 None
 0.74A 3hjoA-5xyiF:
undetectable		 3hjoA-5xyiF:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y0q UPF0348 PROTEIN
B4417_3650

(Bacillus
subtilis) 		no annotation 4 TYR A  72
PHE A  41
VAL A  76
GLY A  45
 None
 0.79A 3hjoA-5y0qA:
undetectable		 3hjoA-5y0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yl7 PSEUDOALTEROMONAS
ARCTICA PAMC 21717

(Pseudoalteromonas
arctica) 		no annotation 4 TYR A 158
VAL A 265
VAL A 473
GLY A 433
 None
 0.95A 3hjoA-5yl7A:
undetectable		 3hjoA-5yl7A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bhu MULTIDRUG
RESISTANCE-ASSOCIATE
D PROTEIN 1

(Bos taurus) 		no annotation 4 VAL A 258
TRP A 261
ILE A 423
GLY A 401
 None
 0.91A 3hjoA-6bhuA:
undetectable		 3hjoA-6bhuA:
0.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d79 SULFATE TRANSPORTER
CYSZ

(Pseudomonas
fragi) 		no annotation 4 VAL A 172
TRP A 203
ILE A 180
GLY A 210
 None
 0.96A 3hjoA-6d79A:
undetectable		 3hjoA-6d79A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fao GLYCOSIDE HYDROLASE
FAMILY 6

(metagenome) 		no annotation 4 VAL A  54
GLN A 151
ILE A  98
GLY A 104
 None
 0.95A 3hjoA-6faoA:
undetectable		 3hjoA-6faoA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fzw COLLAGEN
ALPHA-1(III) CHAIN

(Homo sapiens) 		no annotation 4 VAL A 242
VAL A 221
GLN A 116
ILE A  69
 None
 0.93A 3hjoA-6fzwA:
undetectable		 3hjoA-6fzwA:
15.88