SIMILAR PATTERNS OF AMINO ACIDS FOR 3HCR_A_CHDA4_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bix AP ENDONUCLEASE 1

(Homo sapiens) 		PF03372
(Exo_endo_phos) 		3 LEU A 104
PRO A 105
LEU A 108
 None
 0.50A 3hcrA-1bixA:
0.0		 3hcrA-1bixA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1chm CREATINE
AMIDINOHYDROLASE

(Pseudomonas
putida) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		3 LEU A 367
PRO A 368
LEU A 363
 None
 0.47A 3hcrA-1chmA:
0.0		 3hcrA-1chmA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fch PEROXISOMAL
TARGETING SIGNAL 1
RECEPTOR

(Homo sapiens) 		PF13374
(TPR_10)
PF13432
(TPR_16) 		3 LEU A 600
PRO A 601
LEU A 595
 None
 0.49A 3hcrA-1fchA:
undetectable		 3hcrA-1fchA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gak FERTILIZATION
PROTEIN

(Haliotis
fulgens) 		PF01303
(Egg_lysin) 		3 LEU A  76
PRO A  77
LEU A  71
 None
 0.42A 3hcrA-1gakA:
undetectable		 3hcrA-1gakA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jpd L-ALA-D/L-GLU
EPIMERASE

(Escherichia
coli) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 LEU X 115
PRO X 116
LEU X 321
 None
 0.50A 3hcrA-1jpdX:
3.2		 3hcrA-1jpdX:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k4j ACYL-HOMOSERINELACTO
NE SYNTHASE ESAI

(Pantoea
stewartii) 		PF00765
(Autoind_synth) 		3 LEU A  91
PRO A  92
LEU A  72
 None
 0.48A 3hcrA-1k4jA:
0.6		 3hcrA-1k4jA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1klq MITOTIC SPINDLE
ASSEMBLY CHECKPOINT
PROTEIN MAD2A

(Homo sapiens) 		PF02301
(HORMA) 		3 LEU A 144
PRO A 145
LEU A 147
 None
 0.24A 3hcrA-1klqA:
undetectable		 3hcrA-1klqA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lln ANTIVIRAL PROTEIN 3

(Phytolacca
americana) 		PF00161
(RIP) 		3 LEU A 226
PRO A 227
LEU A 230
 None
None
MLY  A 231 ( 4.0A)
 0.47A 3hcrA-1llnA:
0.0		 3hcrA-1llnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mk2 SMAD 3

(Homo sapiens) 		PF03166
(MH2) 		3 LEU A 403
PRO A 402
LEU A 406
 None
 0.54A 3hcrA-1mk2A:
undetectable		 3hcrA-1mk2A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nne DNA MISMATCH REPAIR
PROTEIN MUTS

(Thermus
aquaticus) 		PF00488
(MutS_V)
PF01624
(MutS_I)
PF05188
(MutS_II)
PF05190
(MutS_IV)
PF05192
(MutS_III) 		3 LEU A 372
PRO A 373
LEU A 359
 None
 0.48A 3hcrA-1nneA:
undetectable		 3hcrA-1nneA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qf7 PROTEIN (CATALASE
HPII)

(Escherichia
coli) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 LEU A 648
PRO A 649
LEU A 632
 None
 0.55A 3hcrA-1qf7A:
2.9		 3hcrA-1qf7A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rfy TRANSCRIPTIONAL
REPRESSOR TRAM

(Agrobacterium
tumefaciens) 		PF09228
(Prok-TraM) 		3 LEU A  17
PRO A  16
LEU A  20
 None
 0.54A 3hcrA-1rfyA:
undetectable		 3hcrA-1rfyA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rp0 THIAZOLE
BIOSYNTHETIC ENZYME

(Arabidopsis
thaliana) 		PF01946
(Thi4) 		3 LEU A 276
PRO A 277
LEU A 271
 None
 0.56A 3hcrA-1rp0A:
undetectable		 3hcrA-1rp0A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1si2 EUKARYOTIC
TRANSLATION
INITIATION FACTOR 2C
1

(Homo sapiens) 		PF02170
(PAZ) 		3 LEU A 323
PRO A 324
LEU A 339
 None
 0.46A 3hcrA-1si2A:
undetectable		 3hcrA-1si2A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1us7 HSP90 CO-CHAPERONE
CDC37

(Homo sapiens) 		PF08564
(CDC37_C)
PF08565
(CDC37_M) 		3 LEU B 301
PRO B 302
LEU B 305
 None
 0.45A 3hcrA-1us7B:
undetectable		 3hcrA-1us7B:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vq0 33 KDA CHAPERONIN

(Thermotoga
maritima) 		PF01430
(HSP33) 		3 LEU A 208
PRO A 207
LEU A 211
 None
 0.54A 3hcrA-1vq0A:
undetectable		 3hcrA-1vq0A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8i PUTATIVE VAPC
RIBONUCLEASE AF_1683

(Archaeoglobus
fulgidus) 		PF01850
(PIN) 		3 LEU A  58
PRO A  59
LEU A  53
 None
 0.53A 3hcrA-1w8iA:
undetectable		 3hcrA-1w8iA:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE

(Salmonella
enterica) 		PF00483
(NTP_transferase) 		3 LEU A 214
PRO A 213
LEU A 217
 None
 0.56A 3hcrA-1wvcA:
2.4		 3hcrA-1wvcA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zlp PETAL DEATH PROTEIN

(Dianthus
caryophyllus) 		PF13714
(PEP_mutase) 		3 LEU A  77
PRO A  78
LEU A  82
 None
 0.52A 3hcrA-1zlpA:
2.5		 3hcrA-1zlpA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zlt SERINE/THREONINE-PRO
TEIN KINASE CHK1

(Homo sapiens) 		PF00069
(Pkinase) 		3 LEU A 239
PRO A 238
LEU A 242
 None
 0.52A 3hcrA-1zltA:
undetectable		 3hcrA-1zltA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a33 HYPOTHETICAL PROTEIN

(Arabidopsis
thaliana) 		PF03641
(Lysine_decarbox) 		3 LEU A 116
PRO A 117
LEU A  57
 None
 0.40A 3hcrA-2a33A:
3.0		 3hcrA-2a33A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b49 PROTEIN TYROSINE
PHOSPHATASE,
NON-RECEPTOR TYPE 3

(Homo sapiens) 		PF00102
(Y_phosphatase) 		3 LEU A 866
PRO A 867
LEU A 861
 None
 0.52A 3hcrA-2b49A:
undetectable		 3hcrA-2b49A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0l PEROXISOMAL
TARGETING SIGNAL 1
RECEPTOR

(Homo sapiens) 		PF00515
(TPR_1)
PF13432
(TPR_16) 		3 LEU A 637
PRO A 638
LEU A 632
 None
 0.53A 3hcrA-2c0lA:
undetectable		 3hcrA-2c0lA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cuk GLYCERATE
DEHYDROGENASE/GLYOXY
LATE REDUCTASE

(Thermus
thermophilus) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 LEU A 266
PRO A 265
LEU A 269
 None
 0.49A 3hcrA-2cukA:
4.9		 3hcrA-2cukA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cy8 D-PHENYLGLYCINE
AMINOTRANSFERASE

(Pseudomonas
stutzeri) 		PF00202
(Aminotran_3) 		3 LEU A 367
PRO A 368
LEU A 353
 None
 0.55A 3hcrA-2cy8A:
2.4		 3hcrA-2cy8A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dh3 4F2 CELL-SURFACE
ANTIGEN HEAVY CHAIN

(Homo sapiens) 		PF00128
(Alpha-amylase) 		3 LEU A 488
PRO A 489
LEU A 510
 None
 0.32A 3hcrA-2dh3A:
undetectable		 3hcrA-2dh3A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ef4 ARGINASE

(Thermus
thermophilus) 		PF00491
(Arginase) 		3 LEU A 140
PRO A 139
LEU A 143
 None
 0.54A 3hcrA-2ef4A:
2.9		 3hcrA-2ef4A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2erj CYTOKINE RECEPTOR
COMMON GAMMA CHAIN

(Homo sapiens) 		PF00041
(fn3)
PF09240
(IL6Ra-bind) 		3 LEU C  35
PRO C  36
LEU C 110
 None
 0.56A 3hcrA-2erjC:
undetectable		 3hcrA-2erjC:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2f02 TAGATOSE-6-PHOSPHATE
KINASE

(Enterococcus
faecalis) 		PF00294
(PfkB) 		3 LEU A 141
PRO A 142
LEU A 137
 None
 0.54A 3hcrA-2f02A:
2.6		 3hcrA-2f02A:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fep CATABOLITE CONTROL
PROTEIN A

(Bacillus
subtilis) 		PF13377
(Peripla_BP_3) 		3 LEU A 210
PRO A 211
LEU A 205
 None
 0.51A 3hcrA-2fepA:
4.2		 3hcrA-2fepA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gqw FERREDOXIN REDUCTASE

(Pseudomonas sp.
KKS102) 		PF07992
(Pyr_redox_2)
PF14759
(Reductase_C) 		3 LEU A 377
PRO A 376
LEU A 380
 None
 0.51A 3hcrA-2gqwA:
2.1		 3hcrA-2gqwA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gv9 DNA POLYMERASE

(Human
alphaherpesvirus
1) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 LEU A1003
PRO A1004
LEU A1007
 None
 0.53A 3hcrA-2gv9A:
undetectable		 3hcrA-2gv9A:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF17221
(COMMD1_N) 		3 LEU A  12
PRO A  11
LEU A  15
 None
 0.51A 3hcrA-2h2mA:
undetectable		 3hcrA-2h2mA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hoq PUTATIVE
HAD-HYDROLASE PH1655

(Pyrococcus
horikoshii) 		PF13419
(HAD_2) 		3 LEU A  71
PRO A  72
LEU A  66
 None
 0.50A 3hcrA-2hoqA:
3.3		 3hcrA-2hoqA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2id0 EXORIBONUCLEASE 2

(Escherichia
coli) 		PF00575
(S1)
PF00773
(RNB)
PF08206
(OB_RNB) 		3 LEU A 262
PRO A 263
LEU A 266
 None
 0.51A 3hcrA-2id0A:
undetectable		 3hcrA-2id0A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6l ALDEHYDE
DEHYDROGENASE FAMILY
7 MEMBER A1

(Homo sapiens) 		PF00171
(Aldedh) 		3 LEU A 216
PRO A 217
LEU A 211
 None
 0.47A 3hcrA-2j6lA:
undetectable		 3hcrA-2j6lA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jg7 ANTIQUITIN

(Acanthopagrus
schlegelii) 		PF00171
(Aldedh) 		3 LEU A 214
PRO A 215
LEU A 209
 None
 0.45A 3hcrA-2jg7A:
3.4		 3hcrA-2jg7A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2k8j P7TM2

(Hepacivirus C) 		no annotation 3 LEU X  16
PRO X  15
LEU X  19
 None
 0.52A 3hcrA-2k8jX:
undetectable		 3hcrA-2k8jX:
5.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mcd MURINE NOROVIRUS 1

(Norwalk virus) 		no annotation 3 LEU A  72
PRO A  73
LEU A  69
 None
 0.53A 3hcrA-2mcdA:
undetectable		 3hcrA-2mcdA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nzu CATABOLITE CONTROL
PROTEIN

(Bacillus
megaterium) 		PF13377
(Peripla_BP_3) 		3 LEU G 209
PRO G 210
LEU G 204
 None
 0.48A 3hcrA-2nzuG:
4.6		 3hcrA-2nzuG:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p0o HYPOTHETICAL PROTEIN
DUF871

(Enterococcus
faecalis) 		PF05913
(DUF871) 		3 LEU A  85
PRO A  84
LEU A  88
 None
 0.55A 3hcrA-2p0oA:
undetectable		 3hcrA-2p0oA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pmp 2-C-METHYL-D-ERYTHRI
TOL
2,4-CYCLODIPHOSPHATE
SYNTHASE

(Arabidopsis
thaliana) 		PF02542
(YgbB) 		3 LEU A  57
PRO A  58
LEU A  52
 None
 0.56A 3hcrA-2pmpA:
undetectable		 3hcrA-2pmpA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppg PUTATIVE ISOMERASE

(Sinorhizobium
meliloti) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 LEU A 161
PRO A 162
LEU A 172
 None
 0.53A 3hcrA-2ppgA:
2.5		 3hcrA-2ppgA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q4d LYSINE
DECARBOXYLASE-LIKE
PROTEIN AT5G11950

(Arabidopsis
thaliana) 		PF03641
(Lysine_decarbox) 		3 LEU A 112
PRO A 113
LEU A  53
 None
 0.35A 3hcrA-2q4dA:
2.9		 3hcrA-2q4dA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v8o FLAVIVIRIN PROTEASE
NS3

(Murray Valley
encephalitis
virus) 		PF00271
(Helicase_C)
PF07652
(Flavi_DEAD) 		3 LEU A 501
PRO A 502
LEU A 505
 None
 0.54A 3hcrA-2v8oA:
3.7		 3hcrA-2v8oA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		3 LEU D 431
PRO D 432
LEU D 426
 None
 0.34A 3hcrA-2vnuD:
undetectable		 3hcrA-2vnuD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vnu EXOSOME COMPLEX
EXONUCLEASE RRP44

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		3 LEU D 604
PRO D 605
LEU D 608
 None
 0.48A 3hcrA-2vnuD:
undetectable		 3hcrA-2vnuD:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wp8 EXOSOME COMPLEX
EXONUCLEASE DIS3

(Saccharomyces
cerevisiae) 		PF00773
(RNB)
PF13638
(PIN_4)
PF17215
(Rrp44_S1)
PF17216
(Rrp44_CSD1) 		3 LEU J 431
PRO J 432
LEU J 426
 None
GOL  J2002 ( 4.1A)
None
 0.36A 3hcrA-2wp8J:
undetectable		 3hcrA-2wp8J:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wv9 FLAVIVIRIN PROTEASE
NS2B REGULATORY
SUBUNIT, FLAVIVIRIN
PROTEASE NS3
CATALYTIC SUBUNIT

(Murray Valley
encephalitis
virus) 		PF00271
(Helicase_C)
PF00949
(Peptidase_S7)
PF01002
(Flavi_NS2B)
PF07652
(Flavi_DEAD) 		3 LEU A 501
PRO A 502
LEU A 505
 None
 0.52A 3hcrA-2wv9A:
3.7		 3hcrA-2wv9A:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xdq LIGHT-INDEPENDENT
PROTOCHLOROPHYLLIDE
REDUCTASE SUBUNIT N

(Thermosynechococcus
elongatus) 		PF00148
(Oxidored_nitro) 		3 LEU A 374
PRO A 375
LEU A   9
 None
 0.40A 3hcrA-2xdqA:
2.5		 3hcrA-2xdqA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwb COMPLEMENT C3B
ALPHA' CHAIN

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		3 LEU B 813
PRO B 814
LEU B 907
 None
 0.54A 3hcrA-2xwbB:
undetectable		 3hcrA-2xwbB:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yqh UDP-N-ACETYLGLUCOSAM
INE
PYROPHOSPHORYLASE

(Candida
albicans) 		PF01704
(UDPGP) 		3 LEU A 202
PRO A 203
LEU A 390
 None
 0.55A 3hcrA-2yqhA:
undetectable		 3hcrA-2yqhA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yys PROLINE
IMINOPEPTIDASE-RELAT
ED PROTEIN

(Thermus
thermophilus) 		PF12697
(Abhydrolase_6) 		3 LEU A  69
PRO A  70
LEU A  75
 None
 0.54A 3hcrA-2yysA:
3.2		 3hcrA-2yysA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-2

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 LEU X 190
PRO X 191
LEU X 185
 None
 0.42A 3hcrA-2zkmX:
3.6		 3hcrA-2zkmX:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-2

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 LEU X 448
PRO X 449
LEU X 318
 None
 0.46A 3hcrA-2zkmX:
3.6		 3hcrA-2zkmX:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ajf NON-STRUCTURAL
PROTEIN 3

(Rice hoja
blanca
tenuivirus) 		PF05310
(Tenui_NS3) 		3 LEU A  97
PRO A  96
LEU A 100
 None
 0.55A 3hcrA-3ajfA:
undetectable		 3hcrA-3ajfA:
16.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqi FERROCHELATASE

(Homo sapiens) 		PF00762
(Ferrochelatase) 		3 LEU A 101
PRO A 102
LEU A 107
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
 0.47A 3hcrA-3aqiA:
53.5		 3hcrA-3aqiA:
99.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c02 AQUAGLYCEROPORIN

(Plasmodium
falciparum) 		PF00230
(MIP) 		3 LEU A 245
PRO A 244
LEU A 248
 None
 0.54A 3hcrA-3c02A:
undetectable		 3hcrA-3c02A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dzm HYPOTHETICAL
CONSERVED PROTEIN

(Thermus
thermophilus) 		no annotation 3 LEU A  31
PRO A  32
LEU A  33
 None
 0.48A 3hcrA-3dzmA:
undetectable		 3hcrA-3dzmA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcp L-ALA-D/L-GLU
EPIMERASE, A
MUCONATE LACTONIZING
ENZYME

(Klebsiella
pneumoniae) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 LEU A 320
PRO A 321
LEU A 298
 None
 0.45A 3hcrA-3fcpA:
2.8		 3hcrA-3fcpA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhc INTERLEUKIN-28B

(Homo sapiens) 		PF15177
(IL28A) 		3 LEU A  90
PRO A  89
LEU A  93
 None
IOD  A 164 ( 4.4A)
None
 0.53A 3hcrA-3hhcA:
undetectable		 3hcrA-3hhcA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmj FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00109
(ketoacyl-synt)
PF01648
(ACPS)
PF02801
(Ketoacyl-synt_C) 		3 LEU A 824
PRO A 825
LEU A 846
 None
 0.45A 3hcrA-3hmjA:
2.0		 3hcrA-3hmjA:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA

(Moorella
thermoacetica) 		PF03063
(Prismane) 		3 LEU A 541
PRO A 542
LEU A 528
 None
 0.55A 3hcrA-3i04A:
3.8		 3hcrA-3i04A:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i27 HEMAGGLUTININ-ESTERA
SE

(Bovine
torovirus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		3 LEU A 148
PRO A 149
LEU A 151
 None
 0.54A 3hcrA-3i27A:
undetectable		 3hcrA-3i27A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i2t EPIDERMAL GROWTH
FACTOR RECEPTOR,
ISOFORM A

(Drosophila
melanogaster) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		3 LEU A  42
PRO A  43
LEU A  47
 None
 0.45A 3hcrA-3i2tA:
undetectable		 3hcrA-3i2tA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iyl VP1

(Aquareovirus C) 		PF06016
(Reovirus_L2) 		3 LEU W 943
PRO W 944
LEU W 946
 None
 0.51A 3hcrA-3iylW:
2.2		 3hcrA-3iylW:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jd5 28S RIBOSOMAL
PROTEIN S25,
MITOCHONDRIAL

(Bos taurus) 		PF14955
(MRP-S24) 		3 LEU c 155
PRO c 156
LEU c 159
 None
 0.52A 3hcrA-3jd5c:
undetectable		 3hcrA-3jd5c:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k7d GLUTAMATE-AMMONIA-LI
GASE
ADENYLYLTRANSFERASE

(Escherichia
coli) 		PF03710
(GlnE)
PF08335
(GlnD_UR_UTase) 		3 LEU A 919
PRO A 920
LEU A 914
 None
 0.56A 3hcrA-3k7dA:
undetectable		 3hcrA-3k7dA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kby PUTATIVE
UNCHARACTERIZED
PROTEIN

(Staphylococcus
aureus) 		PF10804
(DUF2538) 		3 LEU A  94
PRO A  93
LEU A  97
 None
 0.54A 3hcrA-3kbyA:
undetectable		 3hcrA-3kbyA:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lul 4-AMINO-4-DEOXYCHORI
SMATE LYASE

(Legionella
pneumophila) 		PF01063
(Aminotran_4) 		3 LEU A 136
PRO A 135
LEU A 139
 None
None
LLP  A 140 ( 4.2A)
 0.55A 3hcrA-3lulA:
undetectable		 3hcrA-3lulA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m9v FAD-DEPENDENT
OXIDOREDUCTASE

(Actinomadura
kijaniata) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 LEU A 371
PRO A 370
LEU A 374
 None
 0.51A 3hcrA-3m9vA:
undetectable		 3hcrA-3m9vA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mxl NITROSOSYNTHASE

(Micromonospora
sp. ATCC 39149) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 LEU A 362
PRO A 361
LEU A 365
 None
 0.44A 3hcrA-3mxlA:
undetectable		 3hcrA-3mxlA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ngw MOLYBDOPTERIN-GUANIN
E DINUCLEOTIDE
BIOSYNTHESIS PROTEIN
A (MOBA)

(Archaeoglobus
fulgidus) 		PF12804
(NTP_transf_3) 		3 LEU A 153
PRO A 152
LEU A 156
 None
 0.55A 3hcrA-3ngwA:
undetectable		 3hcrA-3ngwA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nip 3-GUANIDINOPROPIONAS
E

(Pseudomonas
aeruginosa) 		PF00491
(Arginase) 		3 LEU A 118
PRO A 119
LEU A 310
 None
 0.56A 3hcrA-3nipA:
3.1		 3hcrA-3nipA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pta DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Homo sapiens) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC) 		3 LEU A1439
PRO A1440
LEU A1495
 None
 0.32A 3hcrA-3ptaA:
undetectable		 3hcrA-3ptaA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3puf RIBONUCLEASE H2
SUBUNIT B

(Homo sapiens) 		PF09468
(RNase_H2-Ydr279) 		3 LEU B  94
PRO B  93
LEU B  97
 None
 0.48A 3hcrA-3pufB:
undetectable		 3hcrA-3pufB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q60 ROP5B

(Toxoplasma
gondii) 		PF14531
(Kinase-like) 		3 LEU A 461
PRO A 462
LEU A 465
 None
 0.52A 3hcrA-3q60A:
undetectable		 3hcrA-3q60A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qr1 PHOSPHOLIPASE C-BETA
(PLC-BETA)

(Doryteuthis
pealeii) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 LEU A 456
PRO A 457
LEU A 329
 None
 0.44A 3hcrA-3qr1A:
3.6		 3hcrA-3qr1A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rko NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT N

(Escherichia
coli) 		no annotation 3 LEU N 139
PRO N 138
LEU N 142
 None
 0.39A 3hcrA-3rkoN:
undetectable		 3hcrA-3rkoN:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sf6 GLUTARYL-COA
DEHYDROGENASE

(Mycolicibacterium
smegmatis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 LEU A 251
PRO A 250
LEU A 254
 None
 0.51A 3hcrA-3sf6A:
undetectable		 3hcrA-3sf6A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3smt HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3

(Homo sapiens) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		3 LEU A 232
PRO A 233
LEU A 234
 None
 0.50A 3hcrA-3smtA:
undetectable		 3hcrA-3smtA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3swo GLUTARYL-COA
DEHYDROGENASE

(Mycolicibacterium
smegmatis) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 LEU A 248
PRO A 247
LEU A 251
 EDO  A 505 (-4.9A)
None
EDO  A 505 (-4.3A)
 0.53A 3hcrA-3swoA:
undetectable		 3hcrA-3swoA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uf5 MACROPHAGE
COLONY-STIMULATING
FACTOR 1

(Mus musculus) 		PF05337
(CSF-1) 		3 LEU A 111
PRO A 110
LEU A 114
 None
 0.51A 3hcrA-3uf5A:
undetectable		 3hcrA-3uf5A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w6j SCPB

(Geobacillus
stearothermophilus) 		PF04079
(SMC_ScpB) 		3 LEU B 134
PRO B 133
LEU B 137
 None
 0.53A 3hcrA-3w6jB:
undetectable		 3hcrA-3w6jB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wo6 MEMBRANE PROTEIN
INSERTASE YIDC 2

(Bacillus
halodurans) 		PF02096
(60KD_IMP) 		3 LEU A 236
PRO A 237
LEU A 240
 None
 0.53A 3hcrA-3wo6A:
undetectable		 3hcrA-3wo6A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zif HEXON PROTEIN

(Bovine
mastadenovirus
B) 		PF01065
(Adeno_hexon)
PF03678
(Adeno_hexon_C) 		3 LEU A 443
PRO A 444
LEU A 447
 None
 0.46A 3hcrA-3zifA:
undetectable		 3hcrA-3zifA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a8j ELONGATOR COMPLEX
PROTEIN 4

(Saccharomyces
cerevisiae) 		PF05625
(PAXNEB) 		3 LEU A 164
PRO A 165
LEU A 247
 None
 0.54A 3hcrA-4a8jA:
2.5		 3hcrA-4a8jA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b98 BETA-ALANINE--PYRUVA
TE TRANSAMINASE

(Pseudomonas
aeruginosa) 		PF00202
(Aminotran_3) 		3 LEU A 107
PRO A 108
LEU A 111
 None
 0.35A 3hcrA-4b98A:
undetectable		 3hcrA-4b98A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bb9 GLUCOKINASE
REGULATORY PROTEIN

(Homo sapiens) 		no annotation 3 LEU A 449
PRO A 448
LEU A 452
 None
 0.53A 3hcrA-4bb9A:
2.6		 3hcrA-4bb9A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bhk FLORICAULA/LEAFY
HOMOLOG 1

(Physcomitrella
patens) 		PF17538
(C_LFY_FLO) 		3 LEU A 305
PRO A 304
LEU A 308
 None
 0.53A 3hcrA-4bhkA:
undetectable		 3hcrA-4bhkA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czb NA(+)/H(+)
ANTIPORTER 1

(Methanocaldococcus
jannaschii) 		PF00999
(Na_H_Exchanger) 		3 LEU A  34
PRO A  33
LEU A  37
 None
 0.50A 3hcrA-4czbA:
undetectable		 3hcrA-4czbA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d25 BMVLG PROTEIN

(Bombyx mori) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 LEU A 508
PRO A 509
LEU A 543
 None
 0.56A 3hcrA-4d25A:
2.4		 3hcrA-4d25A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dzh AMIDOHYDROLASE

(Xanthomonas
campestris) 		PF01979
(Amidohydro_1) 		3 LEU A 247
PRO A 246
LEU A 250
 None
 0.51A 3hcrA-4dzhA:
undetectable		 3hcrA-4dzhA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e5t MANDELATE RACEMASE /
MUCONATE LACTONIZING
ENZYME, C-TERMINAL
DOMAIN PROTEIN

(Labrenzia
alexandrii) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 LEU A 321
PRO A 320
LEU A 324
 None
 0.53A 3hcrA-4e5tA:
undetectable		 3hcrA-4e5tA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0x MALONYL-COA
DECARBOXYLASE,
MITOCHONDRIAL

(Homo sapiens) 		PF05292
(MCD)
PF17408
(MCD_N) 		3 LEU A 398
PRO A 397
LEU A 401
 None
 0.52A 3hcrA-4f0xA:
undetectable		 3hcrA-4f0xA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gio PUTATIVE LIPOPROTEIN

(Campylobacter
jejuni) 		PF07233
(DUF1425) 		3 LEU A  35
PRO A  36
LEU A  31
 BR  A 201 ( 4.8A)
None
None
 0.42A 3hcrA-4gioA:
undetectable		 3hcrA-4gioA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gip FUSION GLYCOPROTEIN
F1

(Mammalian
rubulavirus 5) 		PF00523
(Fusion_gly) 		3 LEU D 305
PRO D 306
LEU D 289
 None
 0.55A 3hcrA-4gipD:
undetectable		 3hcrA-4gipD:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gnk 1-PHOSPHATIDYLINOSIT
OL 4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-3

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 LEU B 453
PRO B 454
LEU B 323
 None
 0.44A 3hcrA-4gnkB:
3.4		 3hcrA-4gnkB:
14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gzi GLUCAN
ENDO-1,3-BETA-D-GLUC
OSIDASE

(Solanum
tuberosum) 		PF00332
(Glyco_hydro_17) 		3 LEU A 194
PRO A 195
LEU A 189
 None
 0.53A 3hcrA-4gziA:
undetectable		 3hcrA-4gziA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 14

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M) 		3 LEU N 118
PRO N 117
LEU N 121
 None
 0.47A 3hcrA-4heaN:
undetectable		 3hcrA-4heaN:
20.48