SIMILAR PATTERNS OF AMINO ACIDS FOR 3HCO_A_CHDA3_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b9g PROTEIN (GROWTH
FACTOR IGF-1)

(Homo sapiens) 		PF00049
(Insulin) 		4 LEU A  41
PRO A   2
LEU A  44
ARG A  21
 None
 1.17A 3hcoA-1b9gA:
undetectable		 3hcoA-1b9gA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0a ASPARTYL TRNA
SYNTHETASE

(Escherichia
coli) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 LEU A 110
PRO A 109
LEU A 127
ARG A  39
 None
G  B 610 ( 4.3A)
None
None
 1.47A 3hcoA-1c0aA:
undetectable		 3hcoA-1c0aA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ccw PROTEIN (GLUTAMATE
MUTASE)

(Clostridium
cochlearium) 		PF06368
(Met_asp_mut_E) 		4 LEU B 146
PRO B 145
LEU B  91
ARG B  80
 None
 1.42A 3hcoA-1ccwB:
undetectable		 3hcoA-1ccwB:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d2f MALY PROTEIN

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 LEU A 328
PRO A 330
LEU A 331
ARG A 387
 None
 1.30A 3hcoA-1d2fA:
2.0		 3hcoA-1d2fA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gtk PORPHOBILINOGEN
DEAMINASE

(Escherichia
coli) 		PF01379
(Porphobil_deam)
PF03900
(Porphobil_deamC) 		4 LEU A  93
PRO A  90
LEU A  71
ARG A  74
 None
 1.08A 3hcoA-1gtkA:
undetectable		 3hcoA-1gtkA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kcz BETA-METHYLASPARTASE

(Clostridium
tetanomorphum) 		PF05034
(MAAL_N)
PF07476
(MAAL_C) 		4 LEU A 304
PRO A 275
LEU A 291
ARG A 298
 None
 1.48A 3hcoA-1kczA:
undetectable		 3hcoA-1kczA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1m0u GST2 GENE PRODUCT

(Drosophila
melanogaster) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 LEU A  64
PRO A  63
LEU A  67
ARG A 115
 None
 1.43A 3hcoA-1m0uA:
undetectable		 3hcoA-1m0uA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p0c NADP-DEPENDENT
ALCOHOL
DEHYDROGENASE

(Pelophylax
perezi) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A1300
PRO A1301
LEU A1302
ARG A1311
 None
 1.44A 3hcoA-1p0cA:
3.4		 3hcoA-1p0cA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qxo CHORISMATE SYNTHASE

(Streptococcus
pneumoniae) 		PF01264
(Chorismate_synt) 		4 LEU A 371
PRO A  22
LEU A 374
ARG A 382
 None
EDO  A3006 (-3.9A)
None
None
 1.10A 3hcoA-1qxoA:
undetectable		 3hcoA-1qxoA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sfs HYPOTHETICAL PROTEIN

(Geobacillus
stearothermophilus) 		PF08924
(DUF1906) 		4 LEU A  36
PRO A  63
LEU A  46
ARG A  48
 None
 1.39A 3hcoA-1sfsA:
undetectable		 3hcoA-1sfsA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u02 TREHALOSE-6-PHOSPHAT
E PHOSPHATASE
RELATED PROTEIN

(Thermoplasma
acidophilum) 		PF02358
(Trehalose_PPase) 		4 LEU A  58
PRO A  57
LEU A  29
ARG A 216
 None
 1.46A 3hcoA-1u02A:
2.1		 3hcoA-1u02A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v47 ATP SULFURYLASE

(Thermus
thermophilus) 		PF01747
(ATP-sulfurylase)
PF14306
(PUA_2) 		4 LEU A  93
PRO A 121
LEU A  95
ARG A 100
 None
 1.36A 3hcoA-1v47A:
2.8		 3hcoA-1v47A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vhk HYPOTHETICAL PROTEIN
YQEU

(Bacillus
subtilis) 		PF04452
(Methyltrans_RNA) 		4 LEU A 239
PRO A 238
LEU A 242
ARG A 145
 None
 1.28A 3hcoA-1vhkA:
3.3		 3hcoA-1vhkA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yni SUCCINYLARGININE
DIHYDROLASE

(Escherichia
coli) 		PF04996
(AstB) 		4 LEU A 417
PRO A 414
LEU A  86
ARG A  74
 None
 1.33A 3hcoA-1yniA:
undetectable		 3hcoA-1yniA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yse DNA-BINDING PROTEIN
SATB1

(Homo sapiens) 		PF02376
(CUT) 		4 LEU A 423
PRO A 415
LEU A 422
ARG A 400
 None
 1.32A 3hcoA-1yseA:
undetectable		 3hcoA-1yseA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6r MLC PROTEIN

(Escherichia
coli) 		PF00480
(ROK) 		4 LEU A 178
PRO A 177
LEU A 125
ARG A 127
 None
 1.43A 3hcoA-1z6rA:
undetectable		 3hcoA-1z6rA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d1y HYPOTHETICAL PROTEIN
TT0321

(Thermus
thermophilus) 		PF13561
(adh_short_C2) 		4 LEU A 109
PRO A 112
LEU A 159
ARG A 161
 None
 1.38A 3hcoA-2d1yA:
3.3		 3hcoA-2d1yA:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d5l DIPEPTIDYL
AMINOPEPTIDASE IV,
PUTATIVE

(Porphyromonas
gingivalis) 		PF00326
(Peptidase_S9)
PF00930
(DPPIV_N) 		4 LEU A 670
PRO A 700
LEU A 666
ARG A 662
 None
 1.43A 3hcoA-2d5lA:
3.6		 3hcoA-2d5lA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfv PROBABLE L-THREONINE
3-DEHYDROGENASE

(Pyrococcus
horikoshii) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 LEU A 182
PRO A 153
LEU A 179
ARG A 204
 None
None
NAD  A1401 (-3.9A)
NAD  A1401 (-3.1A)
 1.41A 3hcoA-2dfvA:
3.1		 3hcoA-2dfvA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2duy COMPETENCE PROTEIN
COMEA-RELATED
PROTEIN

(Thermus
thermophilus) 		PF12836
(HHH_3) 		4 LEU A  66
PRO A  63
LEU A  56
ARG A  51
 None
 1.22A 3hcoA-2duyA:
undetectable		 3hcoA-2duyA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		4 LEU A 358
PRO A 359
LEU A 361
ARG A 423
 None
 1.26A 3hcoA-2eyqA:
3.3		 3hcoA-2eyqA:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ggj N-ACYLAMINO ACID
RACEMASE

(Deinococcus
radiodurans) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 223
PRO A 222
LEU A 234
ARG A 236
 None
 1.44A 3hcoA-2ggjA:
3.1		 3hcoA-2ggjA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gp4 6-PHOSPHOGLUCONATE
DEHYDRATASE

(Shewanella
oneidensis) 		PF00920
(ILVD_EDD) 		4 LEU A 365
PRO A 331
LEU A 360
ARG A 379
 None
 1.47A 3hcoA-2gp4A:
undetectable		 3hcoA-2gp4A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i62 NICOTINAMIDE
N-METHYLTRANSFERASE

(Mus musculus) 		PF01234
(NNMT_PNMT_TEMT) 		4 LEU A 215
PRO A 216
LEU A 217
ARG A 178
 None
 1.41A 3hcoA-2i62A:
undetectable		 3hcoA-2i62A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6h GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE

(Escherichia
coli) 		PF01380
(SIS)
PF13522
(GATase_6) 		4 LEU A 507
PRO A 506
LEU A 502
ARG A 472
 None
 1.40A 3hcoA-2j6hA:
3.2		 3hcoA-2j6hA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6p SB(V)-AS(V)
REDUCTASE

(Leishmania
major) 		PF00581
(Rhodanese) 		4 LEU A  12
PRO A   9
LEU A 106
ARG A  31
 None
 1.13A 3hcoA-2j6pA:
3.4		 3hcoA-2j6pA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m2k HASB PROTEIN

(Serratia
marcescens) 		PF03544
(TonB_C) 		4 LEU A  87
PRO A  88
LEU A  90
ARG A 128
 None
 1.44A 3hcoA-2m2kA:
undetectable		 3hcoA-2m2kA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m56 CAMPHOR
5-MONOOXYGENASE

(Pseudomonas
putida) 		PF00067
(p450) 		4 LEU A 402
PRO A 403
LEU A 404
ARG A 271
 None
 1.34A 3hcoA-2m56A:
undetectable		 3hcoA-2m56A:
25.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwq PROBABLE SHORT-CHAIN
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00106
(adh_short) 		4 LEU A  39
PRO A  54
LEU A  31
ARG A  20
 None
 1.39A 3hcoA-2nwqA:
3.3		 3hcoA-2nwqA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ox6 HYPOTHETICAL PROTEIN
SO3848

(Shewanella
oneidensis) 		PF14590
(DUF4447) 		4 LEU A 107
PRO A 108
LEU A 112
ARG A 119
 None
 1.39A 3hcoA-2ox6A:
3.4		 3hcoA-2ox6A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ppq HOMOSERINE KINASE

(Agrobacterium
fabrum) 		PF01636
(APH) 		4 LEU A 268
PRO A 182
LEU A 219
ARG A 255
 None
 1.47A 3hcoA-2ppqA:
undetectable		 3hcoA-2ppqA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qdd MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Roseovarius
nubinhibens) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A  13
PRO A  14
LEU A 326
ARG A 337
 None
 1.29A 3hcoA-2qddA:
3.7		 3hcoA-2qddA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qob EPHRIN RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A 901
PRO A 844
LEU A 843
ARG A 789
 None
 1.40A 3hcoA-2qobA:
undetectable		 3hcoA-2qobA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vc6 DIHYDRODIPICOLINATE
SYNTHASE

(Sinorhizobium
meliloti) 		PF00701
(DHDPS) 		4 LEU A   9
PRO A  40
LEU A  38
ARG A  69
 None
 1.45A 3hcoA-2vc6A:
undetectable		 3hcoA-2vc6A:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vxo GMP SYNTHASE
[GLUTAMINE-HYDROLYZI
NG]

(Homo sapiens) 		PF00117
(GATase)
PF00958
(GMP_synt_C)
PF02540
(NAD_synthase) 		4 LEU A 512
PRO A 513
LEU A 618
ARG A 677
 None
 1.17A 3hcoA-2vxoA:
2.2		 3hcoA-2vxoA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vzz RV0802C

(Mycobacterium
tuberculosis) 		PF13302
(Acetyltransf_3) 		4 LEU A  80
PRO A  81
LEU A  82
ARG A  11
 None
 1.36A 3hcoA-2vzzA:
undetectable		 3hcoA-2vzzA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zgi PUTATIVE
4-AMINO-4-DEOXYCHORI
SMATE LYASE

(Thermus
thermophilus) 		PF01063
(Aminotran_4) 		4 LEU A 100
PRO A 101
LEU A 104
ARG A 110
 None
 0.90A 3hcoA-2zgiA:
undetectable		 3hcoA-2zgiA:
22.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3aqi FERROCHELATASE

(Homo sapiens) 		PF00762
(Ferrochelatase) 		4 LEU A 101
PRO A 102
LEU A 107
ARG A 114
 CHD  A   3 ( 4.9A)
CHD  A   3 ( 4.7A)
CHD  A   3 ( 4.6A)
CHD  A   2 (-3.6A)
 0.80A 3hcoA-3aqiA:
54.0		 3hcoA-3aqiA:
99.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b5m UNCHARACTERIZED
PROTEIN

(Rhodopirellula
baltica) 		PF04289
(DUF447) 		4 LEU A  39
PRO A  41
LEU A 118
ARG A 105
 None
 1.22A 3hcoA-3b5mA:
undetectable		 3hcoA-3b5mA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bwx ALPHA/BETA HYDROLASE

(Novosphingobium
aromaticivorans) 		PF12697
(Abhydrolase_6) 		4 LEU A  58
PRO A  60
LEU A  32
ARG A 120
 None
None
None
EDO  A 296 (-3.9A)
 1.14A 3hcoA-3bwxA:
2.8		 3hcoA-3bwxA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cqh L-RIBULOSE-5-PHOSPHA
TE 3-EPIMERASE ULAE

(Escherichia
coli) 		PF01261
(AP_endonuc_2) 		4 LEU A  15
PRO A  16
LEU A  27
ARG A 268
 None
 1.48A 3hcoA-3cqhA:
undetectable		 3hcoA-3cqhA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cv3 GLUCURONOSYLTRANSFER
ASE GUMK

(Xanthomonas
campestris) 		no annotation 4 LEU A 184
PRO A 187
LEU A 381
ARG A 196
 None
 1.30A 3hcoA-3cv3A:
undetectable		 3hcoA-3cv3A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eb2 PUTATIVE
DIHYDRODIPICOLINATE
SYNTHETASE

(Rhodopseudomonas
palustris) 		PF00701
(DHDPS) 		4 LEU A  12
PRO A  44
LEU A  42
ARG A  73
 None
 1.41A 3hcoA-3eb2A:
undetectable		 3hcoA-3eb2A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eez PUTATIVE MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Ruegeria
pomeroyi) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A  13
PRO A  14
LEU A 326
ARG A 337
 None
 1.27A 3hcoA-3eezA:
4.1		 3hcoA-3eezA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ege PUTATIVE
METHYLTRANSFERASE
FROM ANTIBIOTIC
BIOSYNTHESIS PATHWAY

(Trichormus
variabilis) 		PF08241
(Methyltransf_11) 		4 LEU A 179
PRO A 180
LEU A 183
ARG A  15
 None
 1.41A 3hcoA-3egeA:
undetectable		 3hcoA-3egeA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f4s PUTATIVE
UNCHARACTERIZED
PROTEIN

(Wolbachia
endosymbiont of
Drosophila
melanogaster) 		PF13462
(Thioredoxin_4) 		4 LEU A  76
PRO A  37
LEU A  33
ARG A  80
 None
 1.40A 3hcoA-3f4sA:
undetectable		 3hcoA-3f4sA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fs5 UNCHARACTERIZED
PROTEIN YGR203W

(Saccharomyces
cerevisiae) 		PF00581
(Rhodanese) 		4 LEU A  17
PRO A  14
LEU A 121
ARG A  39
 None
 1.32A 3hcoA-3fs5A:
3.2		 3hcoA-3fs5A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gxo MMCR

(Streptomyces
lavendulae) 		PF00891
(Methyltransf_2) 		4 LEU A 237
PRO A 238
LEU A 212
ARG A 272
 None
 1.47A 3hcoA-3gxoA:
undetectable		 3hcoA-3gxoA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i2t EPIDERMAL GROWTH
FACTOR RECEPTOR,
ISOFORM A

(Drosophila
melanogaster) 		PF00757
(Furin-like)
PF01030
(Recep_L_domain)
PF14843
(GF_recep_IV) 		4 LEU A  42
PRO A  43
LEU A  47
ARG A  24
 None
 0.88A 3hcoA-3i2tA:
undetectable		 3hcoA-3i2tA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k85 D-GLYCERO-D-MANNO-HE
PTOSE 1-PHOSPHATE
KINASE

(Bacteroides
thetaiotaomicron) 		PF00288
(GHMP_kinases_N)
PF08544
(GHMP_kinases_C) 		4 LEU A 132
PRO A 133
LEU A 134
ARG A  86
 None
 1.28A 3hcoA-3k85A:
undetectable		 3hcoA-3k85A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kfu GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Thermus
thermophilus) 		PF01425
(Amidase) 		4 LEU E 435
PRO E 385
LEU E 383
ARG E 273
 None
 1.45A 3hcoA-3kfuE:
undetectable		 3hcoA-3kfuE:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ksw STEROL 14-ALPHA
DEMETHYLASE

(Trypanosoma
cruzi) 		PF00067
(p450) 		4 LEU A  53
PRO A  52
LEU A 385
ARG A 352
 None
 1.44A 3hcoA-3kswA:
undetectable		 3hcoA-3kswA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l4d STEROL 14-ALPHA
DEMETHYLASE

(Leishmania
infantum) 		PF00067
(p450) 		4 LEU A  53
PRO A  52
LEU A 384
ARG A 351
 None
 1.28A 3hcoA-3l4dA:
undetectable		 3hcoA-3l4dA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omx CG14216

(Drosophila
melanogaster) 		PF04722
(Ssu72) 		4 LEU A  45
PRO A  46
LEU A  82
ARG A  88
 None
 0.84A 3hcoA-3omxA:
5.0		 3hcoA-3omxA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pmk NUCLEOCAPSID PROTEIN

(Recombinant
vesicular
stomatitis
Indiana virus
rVSV-G/GFP) 		PF00945
(Rhabdo_ncap) 		4 LEU A 283
PRO A  28
LEU A 278
ARG A 221
 None
 1.24A 3hcoA-3pmkA:
undetectable		 3hcoA-3pmkA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qit POLYKETIDE SYNTHASE

(Moorea
producens) 		PF00561
(Abhydrolase_1) 		4 LEU A  76
PRO A 214
LEU A  79
ARG A 113
 None
 1.28A 3hcoA-3qitA:
4.0		 3hcoA-3qitA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sdo NITRILOTRIACETATE
MONOOXYGENASE

(Burkholderia
pseudomallei) 		PF00296
(Bac_luciferase) 		4 LEU A 392
PRO A 271
LEU A 394
ARG A  44
 None
 1.44A 3hcoA-3sdoA:
undetectable		 3hcoA-3sdoA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3szb ALDEHYDE
DEHYDROGENASE

(Homo sapiens) 		PF00171
(Aldedh) 		4 LEU A  77
PRO A  78
LEU A  22
ARG A  20
 None
 1.37A 3hcoA-3szbA:
2.7		 3hcoA-3szbA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tgw V-TYPE ATP SYNTHASE
BETA CHAIN

(Methanosarcina
mazei) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		4 LEU A 436
PRO A 437
LEU A 441
ARG A 443
 None
 1.38A 3hcoA-3tgwA:
undetectable		 3hcoA-3tgwA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uki OXYR

(Porphyromonas
gingivalis) 		PF03466
(LysR_substrate) 		4 LEU A 106
PRO A 107
LEU A 105
ARG A 267
 None
 1.39A 3hcoA-3ukiA:
undetectable		 3hcoA-3ukiA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vov GLUCOKINASE

(Thermus
thermophilus) 		PF00480
(ROK) 		4 LEU A 163
PRO A 167
LEU A 180
ARG A 223
 None
None
None
GOL  A 402 (-3.9A)
 1.39A 3hcoA-3vovA:
2.0		 3hcoA-3vovA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c9m CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 LEU A  55
PRO A  54
LEU A  72
ARG A  82
 None
 1.34A 3hcoA-4c9mA:
undetectable		 3hcoA-4c9mA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4edn BETA-PARVIN

(Homo sapiens) 		PF00307
(CH) 		4 LEU A 253
PRO A 250
LEU A 245
ARG A 351
 None
 1.43A 3hcoA-4ednA:
undetectable		 3hcoA-4ednA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g3j STEROL
14-ALPHA-DEMETHYLASE

(Trypanosoma
brucei) 		PF00067
(p450) 		4 LEU A  53
PRO A  52
LEU A 385
ARG A 351
 None
 1.45A 3hcoA-4g3jA:
undetectable		 3hcoA-4g3jA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h19 MANDELATE RACEMASE

(Agrobacterium
fabrum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 232
PRO A 231
LEU A 243
ARG A 245
 None
 1.29A 3hcoA-4h19A:
undetectable		 3hcoA-4h19A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i7u DIHYDRODIPICOLINATE
SYNTHASE

(Agrobacterium
sp. H13-3) 		PF00701
(DHDPS) 		4 LEU A   9
PRO A  41
LEU A  39
ARG A  70
 None
 1.39A 3hcoA-4i7uA:
undetectable		 3hcoA-4i7uA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k0e HEAVY METAL CATION
TRICOMPONENT EFFLUX
PUMP ZNEA(CZCA-LIKE)

(Cupriavidus
metallidurans) 		PF00873
(ACR_tran) 		4 LEU A 517
PRO A1009
LEU A 514
ARG A 509
 None
 1.24A 3hcoA-4k0eA:
undetectable		 3hcoA-4k0eA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mks ENOLASE 2

(Lactobacillus
gasseri) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 LEU A 142
PRO A 143
LEU A 175
ARG A 408
 None
 1.39A 3hcoA-4mksA:
undetectable		 3hcoA-4mksA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4onr DECORIN-BINDING
PROTEIN DBPA

(Borreliella
burgdorferi) 		PF02352
(Decorin_bind) 		4 LEU A 126
PRO A 125
LEU A 129
ARG A  84
 None
 1.41A 3hcoA-4onrA:
undetectable		 3hcoA-4onrA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pzv 2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE/DI
HYDROPTEROATE
SYNTHASE

(Francisella
tularensis) 		PF00809
(Pterin_bind)
PF01288
(HPPK) 		4 LEU A 388
PRO A 383
LEU A 386
ARG A 402
 None
 1.23A 3hcoA-4pzvA:
2.8		 3hcoA-4pzvA:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qax 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Staphylococcus
aureus) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		4 LEU A 486
PRO A 483
LEU A 485
ARG A 324
 None
 1.28A 3hcoA-4qaxA:
3.5		 3hcoA-4qaxA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r89 UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF08774
(VRR_NUC) 		4 LEU A 237
PRO A 236
LEU A 240
ARG A 228
 None
 1.28A 3hcoA-4r89A:
undetectable		 3hcoA-4r89A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rlv ANKYRIN-1, ANKYRIN-2

(Homo sapiens;
Mus musculus) 		PF00023
(Ank)
PF12796
(Ank_2)
PF13637
(Ank_4)
PF13857
(Ank_5) 		4 LEU A2567
PRO A2566
LEU A2582
ARG A2586
 None
 1.49A 3hcoA-4rlvA:
undetectable		 3hcoA-4rlvA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zas CALS13

(Micromonospora
echinospora) 		PF01041
(DegT_DnrJ_EryC1) 		4 LEU A 214
PRO A 215
LEU A 219
ARG A 226
 None
 1.43A 3hcoA-4zasA:
undetectable		 3hcoA-4zasA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zdk CTP SYNTHASE

(Mycobacterium
tuberculosis) 		PF00117
(GATase)
PF06418
(CTP_synth_N) 		4 LEU A 362
PRO A 364
LEU A 306
ARG A 325
 None
 1.27A 3hcoA-4zdkA:
4.2		 3hcoA-4zdkA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a0k LABDANE-RELATED
DITERPENE SYNTHASE

(Streptomyces
sp.) 		no annotation 4 LEU A 132
PRO A 129
LEU A 112
ARG A 156
 None
None
None
GOL  A1324 (-3.1A)
 1.41A 3hcoA-5a0kA:
undetectable		 3hcoA-5a0kA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b01 MOEN5

(Streptomyces
viridosporus) 		no annotation 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.15A 3hcoA-5b01A:
undetectable		 3hcoA-5b01A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b0l MOEN5,DNA-BINDING
PROTEIN 7D

(Sulfolobus
solfataricus;
Streptomyces
viridosporus) 		no annotation 4 LEU A  59
PRO A  39
LEU A  42
ARG A 171
 None
 1.24A 3hcoA-5b0lA:
undetectable		 3hcoA-5b0lA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5brl STAR-RELATED LIPID
TRANSFER PROTEIN 4

(Mus musculus) 		PF01852
(START) 		4 LEU A  93
PRO A  90
LEU A 102
ARG A 116
 None
 1.15A 3hcoA-5brlA:
undetectable		 3hcoA-5brlA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bza BETA-N-ACETYLHEXOSAM
INIDASE

(Thermotoga
neapolitana) 		PF00933
(Glyco_hydro_3) 		4 LEU A 219
PRO A 220
LEU A 223
ARG A 263
 None
 1.12A 3hcoA-5bzaA:
2.6		 3hcoA-5bzaA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cio PYRROLOQUINOLINE
QUINONE BIOSYNTHESIS
PROTEIN PQQF

(Serratia sp.
FS14) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		4 LEU A 404
PRO A 405
LEU A 406
ARG A 245
 None
 1.39A 3hcoA-5cioA:
undetectable		 3hcoA-5cioA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eyt ADENYLOSUCCINATE
LYASE

(Schistosoma
mansoni) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		4 LEU A 372
PRO A 373
LEU A 375
ARG A 151
 None
 1.23A 3hcoA-5eytA:
undetectable		 3hcoA-5eytA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmq INFLUENZA A PB2
SUBUNIT

(Influenza A
virus) 		PF00604
(Flu_PB2) 		4 LEU A 277
PRO A 276
LEU A 502
ARG A 505
 None
 1.38A 3hcoA-5fmqA:
undetectable		 3hcoA-5fmqA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4i PHOSPHOLYASE

(Paenarthrobacter
aurescens) 		PF00202
(Aminotran_3) 		4 LEU A 438
PRO A 439
LEU A 386
ARG A 403
 None
 1.27A 3hcoA-5g4iA:
undetectable		 3hcoA-5g4iA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ikz OXALATE BIOSYNTHETIC
COMPONENT 1

(Burkholderia
thailandensis) 		PF05853
(BKACE) 		4 LEU A 684
PRO A 683
LEU A 729
ARG A 736
 None
 1.38A 3hcoA-5ikzA:
undetectable		 3hcoA-5ikzA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 LEU A 956
PRO A 957
LEU A1021
ARG A1023
 None
 1.45A 3hcoA-5ip9A:
undetectable		 3hcoA-5ip9A:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kyo CYP101J2

(Sphingobium
yanoikuyae) 		PF00067
(p450) 		4 LEU A  54
PRO A  53
LEU A  71
ARG A  81
 None
 1.39A 3hcoA-5kyoA:
undetectable		 3hcoA-5kyoA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l7d SMOOTHENED
HOMOLOG,SOLUBLE
CYTOCHROME
B562,SMOOTHENED
HOMOLOG

(Escherichia
coli;
Homo sapiens) 		PF01392
(Fz)
PF01534
(Frizzled)
PF07361
(Cytochrom_B562) 		4 LEU A 125
PRO A 124
LEU A 146
ARG A 144
 None
 1.22A 3hcoA-5l7dA:
undetectable		 3hcoA-5l7dA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lcw ANAPHASE-PROMOTING
COMPLEX SUBUNIT 1

(Homo sapiens) 		PF12859
(ANAPC1) 		4 LEU A1325
PRO A1322
LEU A1371
ARG A1407
 None
 1.40A 3hcoA-5lcwA:
undetectable		 3hcoA-5lcwA:
11.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5op0 DNA POLYMERASE LIGD,
POLYMERASE DOMAIN

(Mycolicibacterium
smegmatis) 		no annotation 4 LEU B 301
PRO B 300
LEU B 304
ARG B 210
 None
 1.37A 3hcoA-5op0B:
undetectable		 3hcoA-5op0B:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5weg UTP--GLUCOSE-1-PHOSP
HATE
URIDYLYLTRANSFERASE

(Saccharum
hybrid cultivar) 		no annotation 4 LEU A 364
PRO A 365
LEU A 231
ARG A 112
 None
None
None
SO4  A 505 (-4.1A)
 1.48A 3hcoA-5wegA:
undetectable		 3hcoA-5wegA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wrp PYRUVATE KINASE

(Mycobacterium
tuberculosis) 		no annotation 4 LEU A 320
PRO A 319
LEU A  24
ARG A  50
 None
 1.43A 3hcoA-5wrpA:
2.3		 3hcoA-5wrpA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT

(Komagataella
phaffii) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 LEU A 958
PRO A 959
LEU A1023
ARG A1025
 None
 1.49A 3hcoA-5xogA:
undetectable		 3hcoA-5xogA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y2v RUBISCO OPERON
TRANSCRIPTIONAL
REGULATOR

(Synechocystis
sp. PCC 6803) 		no annotation 4 LEU A 111
PRO A 108
LEU A 125
ARG A  94
 None
 1.42A 3hcoA-5y2vA:
undetectable		 3hcoA-5y2vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ze8 CYTOCHROME C552

(Thermochromatium
tepidum) 		no annotation 4 LEU A 418
PRO A 419
LEU A 422
ARG A 319
 None
None
None
HEM  A 502 ( 2.8A)
 1.37A 3hcoA-5ze8A:
undetectable		 3hcoA-5ze8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bs7 ADENYLOSUCCINATE
SYNTHETASE

(Legionella
pneumophila) 		no annotation 4 LEU A 108
PRO A 109
LEU A 187
ARG A 155
 None
 1.42A 3hcoA-6bs7A:
undetectable		 3hcoA-6bs7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d9z SULFATE TRANSPORTER
CYSZ

(Pseudomonas
denitrificans
(nomen
rejiciendum)) 		no annotation 4 LEU F 164
PRO F 163
LEU F 167
ARG F 200
 None
 1.09A 3hcoA-6d9zF:
undetectable		 3hcoA-6d9zF:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ejb XYLOSYLTRANSFERASE 1

(Homo sapiens) 		no annotation 4 LEU A 858
PRO A 762
LEU A 842
ARG A 847
 None
 1.45A 3hcoA-6ejbA:
undetectable		 3hcoA-6ejbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f74 ALCOHOL OXIDASE

(Thermothelomyces
thermophila) 		no annotation 4 LEU A 403
PRO A 320
LEU A 330
ARG A 452
 None
 1.46A 3hcoA-6f74A:
undetectable		 3hcoA-6f74A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gh2 LAMINARIBIOSE
PHOSPHORYLASE

(Paenibacillus
sp. YM1) 		no annotation 4 LEU A  30
PRO A  29
LEU A 112
ARG A 320
 None
None
None
SO4  A1001 (-3.3A)
 1.27A 3hcoA-6gh2A:
undetectable		 3hcoA-6gh2A:
undetectable