SIMILAR PATTERNS OF AMINO ACIDS FOR 3H6T_B_CYZB265
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2zns | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 1 (Homo sapiens) |
PF10613(Lig_chan-Glu_bd) | 6 | LYS A 516PRO A 517MET A 519LEU A 768LEU A 776LYS A 780 | None | 0.84A | 3h6tB-2znsA:37.5 | 3h6tB-2znsA:52.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nks | PROTOPORPHYRINOGENOXIDASE (Homo sapiens) |
PF01593(Amino_oxidase) | 5 | PRO A 287LEU A 294SER A 292LEU A 306LYS A 429 | None | 1.22A | 3h6tB-3nksA:undetectable | 3h6tB-3nksA:19.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qxm | GLUTAMATE RECEPTORIONOTROPIC, KAINATE2 (Homo sapiens) |
PF10613(Lig_chan-Glu_bd) | 6 | LYS A 500PRO A 501MET A 503LEU A 752LEU A 760LYS A 764 | None | 0.82A | 3h6tB-3qxmA:37.0 | 3h6tB-3qxmA:52.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tc3 | UV DAMAGEENDONUCLEASE (Sulfolobusacidocaldarius) |
PF03851(UvdE) | 5 | LYS A 78LEU A 31SER A 35LEU A 38LYS A 42 | None | 0.96A | 3h6tB-3tc3A:undetectable | 3h6tB-3tc3A:24.54 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3u92 | GLUTAMATE RECEPTOR,IONOTROPIC KAINATE 3 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 6 | LYS A 103PRO A 104MET A 106LEU A 234LEU A 242LYS A 246 | NoneNoneNoneNoneNone ZN A 259 (-3.5A) | 0.83A | 3h6tB-3u92A:37.3 | 3h6tB-3u92A:52.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4wxj | GLUTAMATE RECEPTORIIB,GLUTAMATERECEPTOR IIB (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 5 | PRO A 112MET A 114LEU A 245SER A 248LEU A 253 | None | 0.75A | 3h6tB-4wxjA:36.1 | 3h6tB-4wxjA:40.36 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5dtb | CG3822 (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 5 | PRO A 109MET A 111LEU A 242LEU A 250LYS A 254 | None | 0.62A | 3h6tB-5dtbA:38.8 | 3h6tB-5dtbA:54.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ict | GLUTAMATE RECEPTOR 1 (Drosophilamelanogaster) |
PF10613(Lig_chan-Glu_bd) | 5 | LYS A 110PRO A 111MET A 113LEU A 244LEU A 252 | None | 0.98A | 3h6tB-5ictA:39.0 | 3h6tB-5ictA:56.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ikb | GLUTAMATE RECEPTORIONOTROPIC, KAINATE4,GLUTAMATE RECEPTORIONOTROPIC, KAINATE4 (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 6 | LYS A 103PRO A 104MET A 106LEU A 235LEU A 243LYS A 247 | None | 0.88A | 3h6tB-5ikbA:36.4 | 3h6tB-5ikbA:55.73 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l1b | GLUTAMATE RECEPTOR2,GLUTAMATE RECEPTOR2 (Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 6 | LYS A 493PRO A 494MET A 496LEU A 751SER A 754LEU A 759 | None | 0.48A | 3h6tB-5l1bA:22.2 | 3h6tB-5l1bA:34.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5l1b | GLUTAMATE RECEPTOR2,GLUTAMATE RECEPTOR2 (Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 7 | LYS A 493PRO A 494MET A 496SER A 497SER A 754LEU A 759LYS A 763 | None | 0.63A | 3h6tB-5l1bA:22.2 | 3h6tB-5l1bA:34.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wel | CHIMERA OF GLUTAMATERECEPTOR 2, GERMCELL-SPECIFIC GENE1-LIKE PROTEIN (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF07803(GSG-1)PF10613(Lig_chan-Glu_bd) | 7 | LYS A 493PRO A 494MET A 496SER A 497LEU A 751SER A 754LEU A 759 | None | 0.93A | 3h6tB-5welA:32.3 | 3h6tB-5welA:34.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wel | CHIMERA OF GLUTAMATERECEPTOR 2, GERMCELL-SPECIFIC GENE1-LIKE PROTEIN (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF07803(GSG-1)PF10613(Lig_chan-Glu_bd) | 7 | LYS A 493PRO A 494MET A 496SER A 497SER A 754LEU A 759LYS A 763 | None | 1.03A | 3h6tB-5welA:32.3 | 3h6tB-5welA:34.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5weo | GLUTAMATE RECEPTOR2,VOLTAGE-DEPENDENTCALCIUM CHANNELGAMMA-2 SUBUNITCHIMERA (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF00822(PMP22_Claudin)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 5 | LYS A 493MET A 496SER A 497LEU A 751LEU A 759 | NoneCYZ A1302 (-4.3A)CYZ A1302 (-3.2A)NoneNone | 0.66A | 3h6tB-5weoA:25.2 | 3h6tB-5weoA:34.03 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5weo | GLUTAMATE RECEPTOR2,VOLTAGE-DEPENDENTCALCIUM CHANNELGAMMA-2 SUBUNITCHIMERA (Mus musculus;Rattusnorvegicus) |
PF00060(Lig_chan)PF00822(PMP22_Claudin)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 5 | LYS A 493PRO A 494MET A 496SER A 497LEU A 751 | NoneCYZ A1302 (-4.5A)CYZ A1302 (-4.3A)CYZ A1302 (-3.2A)None | 0.67A | 3h6tB-5weoA:25.2 | 3h6tB-5weoA:34.03 |