SIMILAR PATTERNS OF AMINO ACIDS FOR 3H52_C_486C4_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cg4 PROTEIN
(ADENYLOSUCCINATE
SYNTHETASE)

(Escherichia
coli) 		PF00709
(Adenylsucc_synt) 		3 MET A 349
CYH A 344
PRO A 279
 None
 1.18A 3h52C-1cg4A:
0.0		 3h52C-1cg4A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eys PHOTOSYNTHETIC
REACTION CENTER

(Thermochromatium
tepidum) 		PF02276
(CytoC_RC) 		3 MET C 108
CYH C 288
PRO C 140
 HEM  C 610 (-1.9A)
HEM  C 612 (-1.7A)
HEM  C 610 ( 4.8A)
 1.21A 3h52C-1eysC:
undetectable		 3h52C-1eysC:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f0x D-LACTATE
DEHYDROGENASE

(Escherichia
coli) 		PF01565
(FAD_binding_4)
PF09330
(Lact-deh-memb) 		3 MET A  74
CYH A  65
PRO A  52
 FAD  A 600 (-4.7A)
None
None
 1.15A 3h52C-1f0xA:
0.0		 3h52C-1f0xA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fn9 OUTER-CAPSID PROTEIN
SIGMA 3

(Reovirus sp.) 		PF00979
(Reovirus_cap) 		3 MET A   1
CYH A  51
PRO A  69
 None
ZN  A1001 (-2.3A)
None
 1.24A 3h52C-1fn9A:
0.0		 3h52C-1fn9A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg4 ULTRASPIRACLE

(Drosophila
melanogaster) 		PF00104
(Hormone_recep) 		3 MET A 298
CYH A 254
PRO A 499
 None
 0.95A 3h52C-1hg4A:
19.0		 3h52C-1hg4A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jft PURINE NUCLEOTIDE
SYNTHESIS REPRESSOR

(Escherichia
coli) 		PF00356
(LacI)
PF13377
(Peripla_BP_3) 		3 MET A 133
CYH A 123
PRO A 127
 None
 1.26A 3h52C-1jftA:
0.0		 3h52C-1jftA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jlv GLUTATHIONE
TRANSFERASE GST1-3

(Anopheles
cracens) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 MET A 101
CYH A  69
PRO A  11
 GSH  A 701 (-3.7A)
None
GSH  A 701 ( 4.7A)
 1.28A 3h52C-1jlvA:
0.0		 3h52C-1jlvA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k32 TRICORN PROTEASE

(Thermoplasma
acidophilum) 		PF03572
(Peptidase_S41)
PF07676
(PD40)
PF14684
(Tricorn_C1)
PF14685
(Tricorn_PDZ) 		3 MET A  39
CYH A  57
PRO A 314
 None
 1.28A 3h52C-1k32A:
0.0		 3h52C-1k32A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1knr L-ASPARTATE OXIDASE

(Escherichia
coli) 		PF00890
(FAD_binding_2)
PF02910
(Succ_DH_flav_C) 		3 MET A 358
CYH A 503
PRO A 528
 None
 1.04A 3h52C-1knrA:
0.0		 3h52C-1knrA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1n5x XANTHINE
DEHYDROGENASE

(Bos taurus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		3 MET A 927
CYH A 999
PRO A1002
 None
 0.76A 3h52C-1n5xA:
undetectable		 3h52C-1n5xA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1no7 MAJOR CAPSID PROTEIN

(Human
alphaherpesvirus
1) 		PF03122
(Herpes_MCP) 		3 MET A 940
CYH A 661
PRO A 624
 None
 1.24A 3h52C-1no7A:
undetectable		 3h52C-1no7A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oaa SEPIAPTERIN
REDUCTASE

(Mus musculus) 		PF00106
(adh_short) 		3 MET A 206
CYH A 160
PRO A 199
 OAA  A   1 ( 3.5A)
OAA  A   1 ( 3.9A)
NAP  A 800 (-4.1A)
 0.89A 3h52C-1oaaA:
undetectable		 3h52C-1oaaA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oq1 PROTEIN YESU

(Bacillus
subtilis) 		PF09224
(DUF1961) 		3 MET A 160
CYH A  75
PRO A  68
 None
 1.00A 3h52C-1oq1A:
undetectable		 3h52C-1oq1A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pzd COATOMER GAMMA
SUBUNIT

(Bos taurus) 		PF08752
(COP-gamma_platf)
PF16381
(Coatomer_g_Cpla) 		3 MET A 659
CYH A 722
PRO A 713
 None
 1.19A 3h52C-1pzdA:
undetectable		 3h52C-1pzdA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r79 DIACYLGLYCEROL
KINASE, DELTA

(Homo sapiens) 		PF00130
(C1_1) 		3 MET A  26
CYH A  59
PRO A  81
 None
ZN  A 201 (-2.3A)
None
 1.22A 3h52C-1r79A:
undetectable		 3h52C-1r79A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s2t PHOSPHOENOLPYRUVATE
PHOSPHOMUTASE

(Mytilus edulis) 		PF13714
(PEP_mutase) 		3 MET A 234
CYH A 155
PRO A  81
 None
 1.20A 3h52C-1s2tA:
undetectable		 3h52C-1s2tA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sbz PROBABLE AROMATIC
ACID DECARBOXYLASE

(Escherichia
coli) 		PF02441
(Flavoprotein) 		3 MET A 134
CYH A  86
PRO A 146
 None
 1.22A 3h52C-1sbzA:
undetectable		 3h52C-1sbzA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9k PROBABLE
METHYLTHIORIBOSE-1-P
HOSPHATE ISOMERASE

(Thermotoga
maritima) 		PF01008
(IF-2B) 		3 MET A  45
CYH A 154
PRO A 190
 SO4  A 401 ( 4.1A)
SO4  A 401 (-3.6A)
None
 1.19A 3h52C-1t9kA:
undetectable		 3h52C-1t9kA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1urj MAJOR DNA-BINDING
PROTEIN

(Human
alphaherpesvirus
1) 		PF00747
(Viral_DNA_bp) 		3 MET A 516
CYH A 502
PRO A 498
 None
ZN  A2131 (-2.3A)
None
 1.05A 3h52C-1urjA:
undetectable		 3h52C-1urjA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w2w 5-METHYLTHIORIBOSE-1
-PHOSPHATE ISOMERASE

(Saccharomyces
cerevisiae) 		PF01008
(IF-2B) 		3 MET A  48
CYH A 181
PRO B 234
 SO4  A1212 (-4.7A)
SO4  A1212 ( 4.0A)
None
 1.14A 3h52C-1w2wA:
undetectable		 3h52C-1w2wA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a0u INITIATION FACTOR 2B

(Leishmania
major) 		PF01008
(IF-2B) 		3 MET A  58
CYH A 185
PRO A 221
 SO4  A 402 (-4.8A)
SO4  A 402 ( 3.9A)
None
 1.23A 3h52C-2a0uA:
undetectable		 3h52C-2a0uA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bfu COWPEA MOSAIC VIRUS,
SMALL (S) SUBUNIT

(Cowpea mosaic
virus) 		PF02248
(Como_SCP) 		3 MET S  15
CYH S 148
PRO S  41
 None
 0.91A 3h52C-2bfuS:
undetectable		 3h52C-2bfuS:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ch1 3-HYDROXYKYNURENINE
TRANSAMINASE

(Anopheles
gambiae) 		PF00266
(Aminotran_5) 		3 MET A  37
CYH A  29
PRO A 211
 None
 1.25A 3h52C-2ch1A:
undetectable		 3h52C-2ch1A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cpr EXOSOME COMPONENT 10

(Homo sapiens) 		PF00570
(HRDC) 		3 MET A 569
CYH A 554
PRO A 559
 None
 1.15A 3h52C-2cprA:
undetectable		 3h52C-2cprA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		3 MET A 767
CYH A 627
PRO A 760
 None
 1.12A 3h52C-2eyqA:
undetectable		 3h52C-2eyqA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gl5 PUTATIVE DEHYDRATASE
PROTEIN

(Salmonella
enterica) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		3 MET A  20
CYH A 326
PRO A  25
 None
 1.16A 3h52C-2gl5A:
undetectable		 3h52C-2gl5A:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ifx HYPOTHETICAL PROTEIN

(Cupriavidus
necator) 		PF09448
(MmlI) 		3 MET A  79
CYH A  67
PRO A 100
 None
 1.23A 3h52C-2ifxA:
undetectable		 3h52C-2ifxA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n0s FE-HYDROGENASE

(Chlamydomonas
reinhardtii) 		PF02256
(Fe_hyd_SSU)
PF02906
(Fe_hyd_lg_C) 		3 MET A 183
CYH A 377
PRO A 131
 None
SF4  A 501 (-2.6A)
SF4  A 501 (-4.3A)
 1.24A 3h52C-2n0sA:
undetectable		 3h52C-2n0sA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p50 N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE

(Escherichia
coli) 		PF01979
(Amidohydro_1) 		3 MET A   1
CYH A  32
PRO A  38
 None
 1.03A 3h52C-2p50A:
undetectable		 3h52C-2p50A:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p8j S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE

(Clostridium
acetobutylicum) 		PF08241
(Methyltransf_11) 		3 MET A  89
CYH A  29
PRO A  83
 None
 0.79A 3h52C-2p8jA:
undetectable		 3h52C-2p8jA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vpw NRFC PROTEIN

(Thermus
thermophilus) 		PF13247
(Fer4_11) 		3 MET B   6
CYH B 135
PRO B  55
 None
SF4  B1194 (-2.7A)
SF4  B1194 ( 4.9A)
 1.22A 3h52C-2vpwB:
undetectable		 3h52C-2vpwB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wmh FUCOLECTIN-RELATED
PROTEIN

(Streptococcus
pneumoniae) 		PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C) 		3 MET A 128
CYH A 178
PRO A 138
 None
 0.88A 3h52C-2wmhA:
undetectable		 3h52C-2wmhA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT

(Arabidopsis
thaliana) 		PF00503
(G-alpha) 		3 MET A 168
CYH A 152
PRO A 161
 None
 0.94A 3h52C-2xtzA:
undetectable		 3h52C-2xtzA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yxe PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Methanocaldococcus
jannaschii) 		PF01135
(PCMT) 		3 MET A  65
CYH A 199
PRO A 176
 None
 1.18A 3h52C-2yxeA:
undetectable		 3h52C-2yxeA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3anv D-SERINE DEHYDRATASE

(Gallus gallus) 		PF01168
(Ala_racemase_N)
PF14031
(D-ser_dehydrat) 		3 MET A 232
CYH A 177
PRO A 240
 None
None
PLP  A 401 (-4.9A)
 1.01A 3h52C-3anvA:
undetectable		 3h52C-3anvA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asp CAPSID PROTEIN

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		3 MET A 333
CYH A 329
PRO A 324
 None
 1.33A 3h52C-3aspA:
undetectable		 3h52C-3aspA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3byq UNCHARACTERIZED
PROTEIN DUF1185

(Bordetella
bronchiseptica) 		PF06684
(AA_synth) 		3 MET A 129
CYH A  34
PRO A 156
 None
 1.08A 3h52C-3byqA:
undetectable		 3h52C-3byqA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c6g CYTOCHROME P450 2R1

(Homo sapiens) 		PF00067
(p450) 		3 MET A 458
CYH A 448
PRO A 440
 HEM  A 601 ( 4.3A)
HEM  A 601 (-2.1A)
None
 1.32A 3h52C-3c6gA:
2.6		 3h52C-3c6gA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dbg PUTATIVE CYTOCHROME
P450

(Streptomyces
coelicolor) 		PF00067
(p450) 		3 MET A 417
CYH A 410
PRO A 402
 None
HEM  A 500 (-2.3A)
None
 1.21A 3h52C-3dbgA:
1.4		 3h52C-3dbgA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dcp HISTIDINOL-PHOSPHATA
SE

(Listeria
monocytogenes) 		PF02811
(PHP)
PF13263
(PHP_C) 		3 MET A 204
CYH A 185
PRO A 239
 None
 1.09A 3h52C-3dcpA:
undetectable		 3h52C-3dcpA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dp5 CYTOCHROME C FAMILY
PROTEIN

(Geobacter
sulfurreducens) 		PF13442
(Cytochrome_CBB3) 		3 MET A  86
CYH A  35
PRO A  80
 None
HEM  A 122 (-1.9A)
HEM  A 122 ( 4.8A)
 0.73A 3h52C-3dp5A:
undetectable		 3h52C-3dp5A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3efv PUTATIVE
SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Salmonella
enterica) 		PF00171
(Aldedh) 		3 MET A 107
CYH A 452
PRO A 149
 None
 1.24A 3h52C-3efvA:
undetectable		 3h52C-3efvA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egj N-ACETYLGLUCOSAMINE-
6-PHOSPHATE
DEACETYLASE

(Vibrio cholerae) 		PF01979
(Amidohydro_1) 		3 MET A   1
CYH A  32
PRO A  38
 None
 1.23A 3h52C-3egjA:
undetectable		 3h52C-3egjA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3egw RESPIRATORY NITRATE
REDUCTASE 1 BETA
CHAIN

(Escherichia
coli) 		PF13247
(Fer4_11)
PF14711
(Nitr_red_bet_C) 		3 MET B   9
CYH B 263
PRO B 181
 None
F3S  B 802 (-2.3A)
F3S  B 802 ( 4.6A)
 1.13A 3h52C-3egwB:
undetectable		 3h52C-3egwB:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fd5 SELENIDE, WATER
DIKINASE 1

(Homo sapiens) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		3 MET A 187
CYH A 180
PRO A  74
 None
 1.29A 3h52C-3fd5A:
undetectable		 3h52C-3fd5A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g8m SERINE
HYDROXYMETHYLTRANSFE
RASE

(Escherichia
coli) 		PF00464
(SHMT) 		3 MET A 266
CYH A  68
PRO A  60
 None
 1.10A 3h52C-3g8mA:
undetectable		 3h52C-3g8mA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ip1 ALCOHOL
DEHYDROGENASE,
ZINC-CONTAINING

(Thermotoga
maritima) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		3 MET A 355
CYH A 124
PRO A 194
 None
 0.91A 3h52C-3ip1A:
undetectable		 3h52C-3ip1A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3isl PURINE CATABOLISM
PROTEIN PUCG

(Bacillus
subtilis) 		PF00266
(Aminotran_5) 		3 MET A 323
CYH A 201
PRO A  19
 None
 0.99A 3h52C-3islA:
undetectable		 3h52C-3islA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3isr TRANSGLUTAMINASE-LIK
E ENZYMES, PUTATIVE
CYSTEINE PROTEASE

(Cytophaga
hutchinsonii) 		PF01841
(Transglut_core) 		3 MET A   1
CYH A 259
PRO A 225
 None
 1.33A 3h52C-3isrA:
undetectable		 3h52C-3isrA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lnp AMIDOHYDROLASE
FAMILY PROTEIN
OLEI01672_1_465

(Oleispira
antarctica) 		PF01979
(Amidohydro_1) 		3 MET A 370
CYH A 314
PRO A 303
 None
 1.20A 3h52C-3lnpA:
undetectable		 3h52C-3lnpA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwi ZINC TRANSPORT
PROTEIN ZNTB

(Salmonella
enterica) 		PF01544
(CorA) 		3 MET A   3
CYH A 145
PRO A 219
 None
 1.27A 3h52C-3nwiA:
undetectable		 3h52C-3nwiA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omx CG14216

(Drosophila
melanogaster) 		PF04722
(Ssu72) 		3 MET A  85
CYH A  13
PRO A  96
 None
VO4  A 300 (-2.3A)
None
 1.28A 3h52C-3omxA:
undetectable		 3h52C-3omxA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3poc ALPHA-GLUCOSIDASE

(Blautia obeum) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		3 MET A 475
CYH A 488
PRO A 190
 None
 1.01A 3h52C-3pocA:
undetectable		 3h52C-3pocA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r6o 2-HYDROXYHEPTA-2,4-D
IENE-1,
7-DIOATEISOMERASE

(Mycobacteroides
abscessus) 		PF01557
(FAA_hydrolase) 		3 MET A 164
CYH A 199
PRO A  82
 None
 1.22A 3h52C-3r6oA:
undetectable		 3h52C-3r6oA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ruc WBGU

(Plesiomonas
shigelloides) 		PF01370
(Epimerase) 		3 MET A 245
CYH A 237
PRO A 321
 None
 1.21A 3h52C-3rucA:
1.0		 3h52C-3rucA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sr6 XANTHINE
DEHYDROGENASE/OXIDAS
E

(Bos taurus) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		3 MET C 927
CYH C 999
PRO C1002
 None
 0.89A 3h52C-3sr6C:
undetectable		 3h52C-3sr6C:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tp9 BETA-LACTAMASE AND
RHODANESE DOMAIN
PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF00581
(Rhodanese)
PF00753
(Lactamase_B) 		3 MET A 250
CYH A 202
PRO A 244
 None
ZN  A 472 (-3.1A)
None
 1.29A 3h52C-3tp9A:
undetectable		 3h52C-3tp9A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tsy FUSION PROTEIN
4-COUMARATE--COA
LIGASE 1,
RESVERATROL SYNTHASE

(Arabidopsis
thaliana;
Vitis vinifera) 		PF00195
(Chal_sti_synt_N)
PF00501
(AMP-binding)
PF02797
(Chal_sti_synt_C)
PF13193
(AMP-binding_C) 		3 MET A 388
CYH A 291
PRO A 384
 None
 1.15A 3h52C-3tsyA:
undetectable		 3h52C-3tsyA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4boc DNA-DIRECTED RNA
POLYMERASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00940
(RNA_pol)
PF14700
(RPOL_N) 		3 MET A 268
CYH A 319
PRO A 294
 None
 1.26A 3h52C-4bocA:
undetectable		 3h52C-4bocA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c25 L-FUCULOSE PHOSPHATE
ALDOLASE

(Streptococcus
pneumoniae) 		PF00596
(Aldolase_II) 		3 MET A 198
CYH A 177
PRO A 110
 None
 1.30A 3h52C-4c25A:
undetectable		 3h52C-4c25A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3y 3-KETOSTEROID
DEHYDROGENASE

(Rhodococcus
erythropolis) 		PF00890
(FAD_binding_2) 		3 MET A 339
CYH A 353
PRO A 283
 None
 0.93A 3h52C-4c3yA:
undetectable		 3h52C-4c3yA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyk AMIDOHYDROLASE

(Pseudomonas
aeruginosa) 		PF01979
(Amidohydro_1) 		3 MET A 348
CYH A 292
PRO A 281
 None
 1.06A 3h52C-4dykA:
undetectable		 3h52C-4dykA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2z TCAB9

(Micromonospora
chalcea) 		PF08421
(Methyltransf_13)
PF08484
(Methyltransf_14)
PF13489
(Methyltransf_23) 		3 MET A  71
CYH A 180
PRO A 183
 None
 1.29A 3h52C-4e2zA:
undetectable		 3h52C-4e2zA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kq8 CYTOCHROME P450 19A1

(Homo sapiens) 		PF00067
(p450) 		3 MET A 444
CYH A 437
PRO A 429
 None
HEM  A 601 (-2.3A)
None
 1.14A 3h52C-4kq8A:
0.9		 3h52C-4kq8A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]

(Synechocystis
sp. PCC 6803) 		PF02347
(GDC-P) 		3 MET A  48
CYH A 893
PRO A 880
 None
 1.20A 3h52C-4lglA:
undetectable		 3h52C-4lglA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]

(Synechocystis
sp. PCC 6803) 		PF02347
(GDC-P) 		3 MET A 896
CYH A 836
PRO A 526
 None
 0.88A 3h52C-4lglA:
undetectable		 3h52C-4lglA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lgl GLYCINE
DEHYDROGENASE
[DECARBOXYLATING]

(Synechocystis
sp. PCC 6803) 		PF02347
(GDC-P) 		3 MET A 896
CYH A 836
PRO A 866
 None
 1.13A 3h52C-4lglA:
undetectable		 3h52C-4lglA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lr2 BIS(5'-ADENOSYL)-TRI
PHOSPHATASE ENPP4

(Homo sapiens) 		PF01663
(Phosphodiest) 		3 MET A 345
CYH A 243
PRO A 267
 None
 1.17A 3h52C-4lr2A:
undetectable		 3h52C-4lr2A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6v NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT A

(Vibrio cholerae) 		PF05896
(NQRA)
PF11973
(NQRA_SLBB) 		3 MET A 388
CYH A 421
PRO A 385
 None
 1.23A 3h52C-4p6vA:
undetectable		 3h52C-4p6vA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0w YEAZ

(Pseudomonas
aeruginosa) 		PF00814
(Peptidase_M22) 		3 MET A 173
CYH A 127
PRO A 177
 None
 1.17A 3h52C-4y0wA:
undetectable		 3h52C-4y0wA:
25.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysw XANTHINE
DEHYDROGENASE/OXIDAS
E

(Rattus
norvegicus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		3 MET A 927
CYH A 999
PRO A1002
 None
 0.89A 3h52C-4yswA:
undetectable		 3h52C-4yswA:
11.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zbt ACETOACETATE
DECARBOXYLASE

(Streptomyces
bingchenggensis) 		PF06314
(ADC) 		3 MET A 258
CYH A  93
PRO A 181
 None
 1.05A 3h52C-4zbtA:
undetectable		 3h52C-4zbtA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bq2 UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE

(Pseudomonas
aeruginosa) 		PF00275
(EPSP_synthase) 		3 MET A 173
CYH A 200
PRO A  27
 None
 1.29A 3h52C-5bq2A:
undetectable		 3h52C-5bq2A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5d9a POLYMERASE BASIC
PROTEIN 2
RNA-DIRECTED RNA
POLYMERASE CATALYTIC
SUBUNIT

(Influenza C
virus) 		PF00602
(Flu_PB1)
PF00604
(Flu_PB2) 		3 MET C  67
CYH C 111
PRO B 628
 None
 0.80A 3h52C-5d9aC:
undetectable		 3h52C-5d9aC:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fq6 PUTATIVE LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF12771
(SusD-like_2) 		3 MET A 290
CYH A 249
PRO A 284
 None
 1.26A 3h52C-5fq6A:
undetectable		 3h52C-5fq6A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hi9 TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 2

(Rattus
norvegicus) 		PF00520
(Ion_trans)
PF12796
(Ank_2) 		3 MET A 372
CYH A 364
PRO A 367
 None
 1.12A 3h52C-5hi9A:
undetectable		 3h52C-5hi9A:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i2g DIOL DEHYDRATASE

(Roseburia
inulinivorans) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		3 MET A 294
CYH A 367
PRO A 287
 None
 1.26A 3h52C-5i2gA:
undetectable		 3h52C-5i2gA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5il0 METTL3

(Homo sapiens) 		PF05063
(MT-A70) 		3 MET A 520
CYH A 483
PRO A 514
 None
 0.51A 3h52C-5il0A:
undetectable		 3h52C-5il0A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
2, MITOCHONDRIAL
NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL

(Bos taurus) 		PF00346
(Complex1_49kDa)
PF01058
(Oxidored_q6) 		3 MET D 111
CYH B  54
PRO B 150
 None
SF4  B 201 (-2.2A)
SF4  B 201 (-4.1A)
 1.34A 3h52C-5lc5D:
undetectable		 3h52C-5lc5D:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lc5 NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL

(Bos taurus) 		PF01058
(Oxidored_q6) 		3 MET B  86
CYH B 136
PRO B 141
 None
 1.25A 3h52C-5lc5B:
undetectable		 3h52C-5lc5B:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldw NADH DEHYDROGENASE
[UBIQUINONE]
IRON-SULFUR PROTEIN
7, MITOCHONDRIAL

(Bos taurus) 		PF01058
(Oxidored_q6) 		3 MET B  86
CYH B 136
PRO B 141
 None
 1.31A 3h52C-5ldwB:
undetectable		 3h52C-5ldwB:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lj3 PRE-MRNA-SPLICING
FACTOR SLT11

(Saccharomyces
cerevisiae) 		no annotation 3 MET N  25
CYH N  73
PRO N  10
 None
 1.33A 3h52C-5lj3N:
undetectable		 3h52C-5lj3N:
24.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mz8 ALDEHYDE
DEHYDROGENASE 21

(Physcomitrella
patens) 		PF00171
(Aldedh) 		3 MET A 166
CYH A 189
PRO A 183
 None
 1.32A 3h52C-5mz8A:
undetectable		 3h52C-5mz8A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 3 MET A 812
CYH A 664
PRO A 806
 None
 0.80A 3h52C-5nd1A:
undetectable		 3h52C-5nd1A:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tey N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT

(Homo sapiens) 		PF05063
(MT-A70) 		3 MET A 520
CYH A 483
PRO A 514
 None
 0.62A 3h52C-5teyA:
undetectable		 3h52C-5teyA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ub6 PHOSPHATE-BINDING
PROTEIN

(Xanthomonas
citri) 		no annotation 3 MET A 189
CYH A 170
PRO A 159
 None
 1.03A 3h52C-5ub6A:
undetectable		 3h52C-5ub6A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vem ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5

(Homo sapiens) 		PF01663
(Phosphodiest) 		3 MET A 348
CYH A 244
PRO A 268
 None
 1.22A 3h52C-5vemA:
undetectable		 3h52C-5vemA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5veo ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 5

(Mus musculus) 		PF01663
(Phosphodiest) 		3 MET A 348
CYH A 244
PRO A 268
 None
 1.19A 3h52C-5veoA:
undetectable		 3h52C-5veoA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wt3 TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A

(Pyrococcus
abyssi) 		no annotation 3 MET A 170
CYH A 326
PRO A 260
 G  C  37 ( 4.4A)
None
None
 1.24A 3h52C-5wt3A:
undetectable		 3h52C-5wt3A:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yg7 RIBOSE
1,5-BISPHOSPHATE
ISOMERASE

(Pyrococcus
horikoshii) 		no annotation 3 MET A  19
CYH A 135
PRO A 163
 RI2  A 401 (-4.5A)
RI2  A 401 (-3.6A)
None
 1.00A 3h52C-5yg7A:
undetectable		 3h52C-5yg7A:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yk2 PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER

(Mycobacterium
tuberculosis) 		no annotation 3 MET A 381
CYH A 420
PRO A 365
 None
 1.32A 3h52C-5yk2A:
undetectable		 3h52C-5yk2A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6btg FUCULOSE PHOSPHATE
ALDOLASE

(Bacillus
thuringiensis) 		no annotation 3 MET A 200
CYH A 179
PRO A 112
 None
 1.24A 3h52C-6btgA:
undetectable		 3h52C-6btgA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c93 CYTOCHROME P450 4B1

(Oryctolagus
cuniculus) 		no annotation 3 MET A 455
CYH A 448
PRO A 374
 None
HEM  A 600 (-2.1A)
HEM  A 600 (-4.0A)
 1.26A 3h52C-6c93A:
1.1		 3h52C-6c93A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c93 CYTOCHROME P450 4B1

(Oryctolagus
cuniculus) 		no annotation 3 MET A 455
CYH A 448
PRO A 440
 None
HEM  A 600 (-2.1A)
None
 1.07A 3h52C-6c93A:
1.1		 3h52C-6c93A:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cza -

(-) 		no annotation 3 MET B   5
CYH B 183
PRO B  54
 None
SF4  B 301 (-2.3A)
SF4  B 301 ( 4.8A)
 1.17A 3h52C-6czaB:
undetectable		 3h52C-6czaB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f0k FE-S-CLUSTER-CONTAIN
ING HYDROGENASE

(Rhodothermus
marinus) 		no annotation 3 MET B 800
CYH B 980
PRO B 862
 SF4  B1103 ( 4.7A)
SF4  B1104 (-2.2A)
None
 1.14A 3h52C-6f0kB:
undetectable		 3h52C-6f0kB:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC1
DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC2

(Saccharomyces
cerevisiae) 		no annotation 3 MET B1101
CYH A  77
PRO A 265
 None
ZN  A1501 ( 4.9A)
None
 1.31A 3h52C-6f42B:
undetectable		 3h52C-6f42B:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f42 DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC8
DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC9

(Saccharomyces
cerevisiae) 		no annotation 3 MET D   1
CYH G  45
PRO G  40
 None
 1.29A 3h52C-6f42D:
undetectable		 3h52C-6f42D:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fik POLYKETIDE SYNTHASE

(Cercospora
nicotianae) 		no annotation 3 MET A 966
CYH A 987
PRO A 961
 None
 1.17A 3h52C-6fikA:
undetectable		 3h52C-6fikA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6flk CEP120

(Homo sapiens) 		no annotation 3 MET A 501
CYH A 474
PRO A 471
 None
 1.15A 3h52C-6flkA:
undetectable		 3h52C-6flkA:
14.67