SIMILAR PATTERNS OF AMINO ACIDS FOR 3H0A_A_9RAA500_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bco BACTERIOPHAGE MU
TRANSPOSASE

(Escherichia
virus Mu) 		PF02914
(DDE_2)
PF09299
(Mu-transpos_C) 		3 ILE A 266
PHE A 318
HIS A 375
 None
 0.71A 3h0aA-1bcoA:
undetectable		 3h0aA-1bcoA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4k PROTEIN (ORNITHINE
DECARBOXYLASE)

(Lactobacillus
sp. 30A) 		PF01276
(OKR_DC_1)
PF03709
(OKR_DC_1_N)
PF03711
(OKR_DC_1_C) 		3 ILE A 251
PHE A 616
HIS A 223
 None
None
PLP  A 955 (-3.4A)
 0.68A 3h0aA-1c4kA:
0.0		 3h0aA-1c4kA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eyw PHOSPHOTRIESTERASE

(Brevundimonas
diminuta) 		PF02126
(PTE) 		3 ILE A 228
PHE A 216
HIS A  55
 None
None
ZN  A 401 (-3.2A)
 0.72A 3h0aA-1eywA:
undetectable		 3h0aA-1eywA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eyw PHOSPHOTRIESTERASE

(Brevundimonas
diminuta) 		PF02126
(PTE) 		3 ILE A 228
PHE A 216
HIS A 201
 None
None
ZN  A 402 (-3.1A)
 0.76A 3h0aA-1eywA:
undetectable		 3h0aA-1eywA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k9a CARBOXYL-TERMINAL
SRC KINASE

(Rattus
norvegicus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		3 ILE A 379
PHE A 382
HIS A 449
 None
 0.70A 3h0aA-1k9aA:
0.0		 3h0aA-1k9aA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kfi PHOSPHOGLUCOMUTASE 1

(Paramecium
tetraurelia) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		3 ILE A 118
PHE A  47
HIS A  91
 None
 0.75A 3h0aA-1kfiA:
0.0		 3h0aA-1kfiA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nsv GALACTOSE MUTAROTASE

(Lactococcus
lactis) 		PF01263
(Aldose_epim) 		3 ILE A 278
PHE A 219
HIS A 298
 None
 0.73A 3h0aA-1nsvA:
undetectable		 3h0aA-1nsvA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1psz PROTEIN (SURFACE
ANTIGEN PSAA)

(Streptococcus
pneumoniae) 		PF01297
(ZnuA) 		3 ILE A  41
PHE A 150
HIS A  67
 None
None
ZN  A1000 ( 3.2A)
 0.66A 3h0aA-1pszA:
undetectable		 3h0aA-1pszA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q56 AGRIN

(Gallus gallus) 		PF00054
(Laminin_G_1) 		3 ILE A  97
PHE A 163
HIS A 101
 None
 0.70A 3h0aA-1q56A:
undetectable		 3h0aA-1q56A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA
CYTOCHROME C OXIDASE
POLYPEPTIDE III

(Paracoccus
denitrificans) 		PF00115
(COX1)
PF00510
(COX3) 		3 ILE A 194
PHE C  93
HIS A 187
 None
 0.73A 3h0aA-1qleA:
0.2		 3h0aA-1qleA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r5m SIR4-INTERACTING
PROTEIN SIF2

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		3 ILE A 286
PHE A 299
HIS A 275
 None
 0.64A 3h0aA-1r5mA:
undetectable		 3h0aA-1r5mA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rif DNA HELICASE UVSW

(Escherichia
virus T4) 		PF04851
(ResIII) 		3 ILE A  15
PHE A  22
HIS A  12
 None
 0.70A 3h0aA-1rifA:
undetectable		 3h0aA-1rifA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s5j DNA POLYMERASE I

(Sulfolobus
solfataricus) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 ILE A 120
PHE A 128
HIS A 463
 None
SO4  A 891 ( 4.3A)
None
 0.70A 3h0aA-1s5jA:
0.0		 3h0aA-1s5jA:
14.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1uhl RETINOIC ACID
RECEPTOR RXR-BETA

(Homo sapiens) 		PF00104
(Hormone_recep) 		3 ILE A 339
PHE A 384
HIS A 506
 MEI  A1001 (-3.8A)
MEI  A1001 (-4.5A)
None
 0.52A 3h0aA-1uhlA:
32.0		 3h0aA-1uhlA:
88.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ui1 URACIL-DNA
GLYCOSYLASE

(Thermus
thermophilus) 		PF03167
(UDG) 		3 ILE A 178
PHE A 151
HIS A 172
 None
 0.74A 3h0aA-1ui1A:
undetectable		 3h0aA-1ui1A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8j MYOSIN VA

(Gallus gallus) 		PF00063
(Myosin_head) 		3 ILE A 332
PHE A 360
HIS A 406
 None
 0.74A 3h0aA-1w8jA:
0.8		 3h0aA-1w8jA:
16.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1xiu RXR-LIKE PROTEIN

(Biomphalaria
glabrata) 		PF00104
(Hormone_recep) 		3 ILE A 242
PHE A 287
HIS A 409
 9CR  A 201 ( 4.4A)
9CR  A 201 (-4.7A)
9CR  A 201 (-4.8A)
 0.55A 3h0aA-1xiuA:
29.4		 3h0aA-1xiuA:
82.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1xls RETINOIC ACID
RECEPTOR RXR-ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep) 		3 ILE A 268
PHE A 313
HIS A 435
 9CR  A 801 (-3.9A)
9CR  A 801 (-4.3A)
None
 0.54A 3h0aA-1xlsA:
31.5		 3h0aA-1xlsA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xmx HYPOTHETICAL PROTEIN
VC1899

(Vibrio cholerae) 		PF09002
(DUF1887) 		3 ILE A  73
PHE A  89
HIS A  97
 None
 0.59A 3h0aA-1xmxA:
undetectable		 3h0aA-1xmxA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y63 LMAJ004144AAA
PROTEIN

(Leishmania
major) 		PF13238
(AAA_18) 		3 ILE A  13
PHE A 101
HIS A  39
 None
None
MN  A 311 (-3.3A)
 0.68A 3h0aA-1y63A:
undetectable		 3h0aA-1y63A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6y ADP-RIBOSYLATION
FACTOR-LIKE PROTEIN
5

(Homo sapiens) 		PF00025
(Arf) 		3 ILE A  88
PHE A  36
HIS A 153
 None
 0.67A 3h0aA-1z6yA:
undetectable		 3h0aA-1z6yA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2as9 SERINE PROTEASE

(Staphylococcus
aureus) 		PF00089
(Trypsin) 		3 ILE A  36
PHE A 107
HIS A 201
 None
 0.72A 3h0aA-2as9A:
undetectable		 3h0aA-2as9A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b61 HOMOSERINE
O-ACETYLTRANSFERASE

(Haemophilus
influenzae) 		PF00561
(Abhydrolase_1) 		3 ILE A 133
PHE A  81
HIS A 130
 None
 0.68A 3h0aA-2b61A:
undetectable		 3h0aA-2b61A:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dfs MYOSIN-5A

(Gallus gallus) 		PF00063
(Myosin_head)
PF00612
(IQ) 		3 ILE A 332
PHE A 360
HIS A 406
 None
 0.66A 3h0aA-2dfsA:
undetectable		 3h0aA-2dfsA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e6m WERNER SYNDROME
ATP-DEPENDENT
HELICASE HOMOLOG

(Mus musculus) 		PF01612
(DNA_pol_A_exo1) 		3 ILE A  94
PHE A 145
HIS A 107
 None
 0.71A 3h0aA-2e6mA:
undetectable		 3h0aA-2e6mA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fpg SUCCINYL-COA LIGASE
[GDP-FORMING]
ALPHA-CHAIN,
MITOCHONDRIAL

(Sus scrofa) 		PF00549
(Ligase_CoA)
PF02629
(CoA_binding) 		3 ILE A 156
PHE A 203
HIS A 151
 None
 0.72A 3h0aA-2fpgA:
undetectable		 3h0aA-2fpgA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6y GREEN FLUORESCENT
PROTEIN 2

(Pontellina
plumata) 		PF01353
(GFP) 		3 ILE A 180
PHE A  74
HIS A 143
 None
 0.55A 3h0aA-2g6yA:
undetectable		 3h0aA-2g6yA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h6o MAJOR OUTER ENVELOPE
GLYCOPROTEIN GP350

(Human
gammaherpesvirus
4) 		PF05109
(Herpes_BLLF1) 		3 ILE A  50
PHE A  26
HIS A 143
 None
 0.74A 3h0aA-2h6oA:
undetectable		 3h0aA-2h6oA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h8x XENOBIOTIC REDUCTASE
A

(Pseudomonas
putida) 		PF00724
(Oxidored_FMN) 		3 ILE A  89
PHE A 172
HIS A  41
 None
 0.75A 3h0aA-2h8xA:
undetectable		 3h0aA-2h8xA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i0k OXIDOREDUCTASE

(Brevibacterium
sterolicum) 		PF01565
(FAD_binding_4)
PF09129
(Chol_subst-bind) 		3 ILE A 513
PHE A 300
HIS A 202
 None
None
FAD  A 700 (-3.9A)
 0.72A 3h0aA-2i0kA:
undetectable		 3h0aA-2i0kA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ify 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Bacillus
anthracis) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		3 ILE A 440
PHE A  13
HIS A  41
 None
 0.71A 3h0aA-2ifyA:
undetectable		 3h0aA-2ifyA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2im9 HYPOTHETICAL PROTEIN

(Legionella
pneumophila) 		PF07313
(DUF1460) 		3 ILE A 335
PHE A 247
HIS A 291
 None
 0.65A 3h0aA-2im9A:
undetectable		 3h0aA-2im9A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jhq URACIL
DNA-GLYCOSYLASE

(Vibrio cholerae) 		PF03167
(UDG) 		3 ILE A  60
PHE A 203
HIS A 187
 None
 0.70A 3h0aA-2jhqA:
undetectable		 3h0aA-2jhqA:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jnk HYALURONONGLUCOSAMIN
IDASE

(Clostridium
perfringens) 		PF00404
(Dockerin_1)
PF07554
(FIVAR) 		3 ILE A 118
PHE A  84
HIS A  30
 None
 0.67A 3h0aA-2jnkA:
undetectable		 3h0aA-2jnkA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o5h HYPOTHETICAL PROTEIN

(Neisseria
meningitidis) 		PF04591
(DUF596) 		3 ILE A  54
PHE A  41
HIS A   7
 None
 0.67A 3h0aA-2o5hA:
undetectable		 3h0aA-2o5hA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oca ATP-DEPENDENT DNA
HELICASE UVSW

(Escherichia
virus T4) 		PF00271
(Helicase_C)
PF04851
(ResIII) 		3 ILE A  15
PHE A  22
HIS A  12
 None
 0.74A 3h0aA-2ocaA:
undetectable		 3h0aA-2ocaA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p5z TYPE VI SECRETION
SYSTEM COMPONENT

(Escherichia
coli) 		PF05954
(Phage_GPD) 		3 ILE X 197
PHE X 150
HIS X 141
 None
 0.73A 3h0aA-2p5zX:
undetectable		 3h0aA-2p5zX:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME

(Bos taurus) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		3 ILE A 290
PHE A 498
HIS A 196
 None
 0.56A 3h0aA-2pncA:
undetectable		 3h0aA-2pncA:
14.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qfb PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58

(Homo sapiens) 		PF11648
(RIG-I_C-RD) 		3 ILE A 862
PHE A 838
HIS A 871
 None
 0.63A 3h0aA-2qfbA:
undetectable		 3h0aA-2qfbA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r2i GUANYLYL
CYCLASE-ACTIVATING
PROTEIN 1

(Gallus gallus) 		PF00036
(EF-hand_1)
PF13499
(EF-hand_7) 		3 ILE A 118
PHE A  62
HIS A 176
 None
MYR  A   1 ( 4.7A)
None
 0.51A 3h0aA-2r2iA:
undetectable		 3h0aA-2r2iA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uvf EXOPOLYGALACTURONASE

(Yersinia
enterocolitica) 		PF00295
(Glyco_hydro_28)
PF12708
(Pectate_lyase_3) 		3 ILE A 448
PHE A 519
HIS A 443
 None
None
AD0  A1617 (-3.8A)
 0.70A 3h0aA-2uvfA:
undetectable		 3h0aA-2uvfA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2van DNA POLYMERSE BETA

(Rattus
norvegicus) 		PF10391
(DNA_pol_lambd_f)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		3 ILE A 255
PHE A 235
HIS A 252
 None
 0.76A 3h0aA-2vanA:
undetectable		 3h0aA-2vanA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vr5 GLYCOGEN OPERON
PROTEIN GLGX

(Sulfolobus
solfataricus) 		PF00128
(Alpha-amylase)
PF02806
(Alpha-amylase_C)
PF02922
(CBM_48) 		3 ILE A 307
PHE A  99
HIS A 337
 None
 0.73A 3h0aA-2vr5A:
undetectable		 3h0aA-2vr5A:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4g MYOSIN HEAVY CHAIN,
SKELETAL MUSCLE,
ADULT

(Gallus gallus) 		PF00063
(Myosin_head)
PF02736
(Myosin_N) 		3 ILE M 175
PHE M 196
HIS M 668
 None
 0.59A 3h0aA-2w4gM:
1.2		 3h0aA-2w4gM:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wqq ALPHA-2,3-/2,8-SIALY
LTRANSFERASE

(Campylobacter
jejuni) 		PF06002
(CST-I) 		3 ILE A 130
PHE A 109
HIS A 122
 None
 0.76A 3h0aA-2wqqA:
undetectable		 3h0aA-2wqqA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x3l ORN/LYS/ARG
DECARBOXYLASE FAMILY
PROTEIN

(Staphylococcus
aureus) 		PF01276
(OKR_DC_1)
PF03711
(OKR_DC_1_C) 		3 ILE A 408
PHE A 410
HIS A 133
 None
 0.67A 3h0aA-2x3lA:
undetectable		 3h0aA-2x3lA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y9y IMITATION SWITCH
PROTEIN 1
(DEL_ATPASE)
ISWI ONE COMPLEX
PROTEIN 3

(Saccharomyces
cerevisiae) 		PF09110
(HAND)
PF09111
(SLIDE)
PF15612
(WHIM1) 		3 ILE A 947
PHE A 895
HIS B 346
 None
 0.76A 3h0aA-2y9yA:
undetectable		 3h0aA-2y9yA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zbl PUTATIVE ISOMERASE

(Salmonella
enterica) 		PF07221
(GlcNAc_2-epim) 		3 ILE A 381
PHE A  21
HIS A 386
 None
 0.73A 3h0aA-2zblA:
undetectable		 3h0aA-2zblA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bks STEROL CARRIER
PROTEIN-2 LIKE-3

(Aedes aegypti) 		PF02036
(SCP2) 		3 ILE A 103
PHE A  92
HIS A  33
 None
 0.70A 3h0aA-3bksA:
undetectable		 3h0aA-3bksA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bmw CYCLOMALTODEXTRIN
GLUCANOTRANSFERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG) 		3 ILE A  76
PHE A 113
HIS A 328
 None
None
ACI  A 694 (-3.9A)
 0.75A 3h0aA-3bmwA:
undetectable		 3h0aA-3bmwA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d7u TYROSINE-PROTEIN
KINASE CSK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		3 ILE A 379
PHE A 382
HIS A 449
 None
 0.70A 3h0aA-3d7uA:
undetectable		 3h0aA-3d7uA:
22.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3dzu RETINOIC ACID
RECEPTOR RXR-ALPHA

(Homo sapiens) 		PF00104
(Hormone_recep)
PF00105
(zf-C4) 		3 ILE A 268
PHE A 313
HIS A 435
 9CR  A7223 (-3.9A)
9CR  A7223 (-4.5A)
9CR  A7223 (-4.3A)
 0.66A 3h0aA-3dzuA:
31.5		 3h0aA-3dzuA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gmf PROTEIN-DISULFIDE
ISOMERASE

(Novosphingobium
aromaticivorans) 		PF13462
(Thioredoxin_4) 		3 ILE A 111
PHE A 170
HIS A 124
 None
 0.75A 3h0aA-3gmfA:
undetectable		 3h0aA-3gmfA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT B

(Sulfolobus
solfataricus) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 ILE B 655
PHE B 456
HIS B 660
 None
 0.70A 3h0aA-3hkzB:
undetectable		 3h0aA-3hkzB:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2

(Burkholderia
cepacia) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		3 ILE A3220
PHE A3258
HIS A3201
 None
 0.68A 3h0aA-3hwcA:
undetectable		 3h0aA-3hwcA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i99 UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(Vibrio cholerae) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		3 ILE A 304
PHE A 244
HIS A 289
 None
 0.64A 3h0aA-3i99A:
undetectable		 3h0aA-3i99A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j0c E1 ENVELOPE
GLYCOPROTEIN

(Venezuelan
equine
encephalitis
virus) 		PF01589
(Alpha_E1_glycop) 		3 ILE A 177
PHE A 189
HIS A 125
 None
 0.63A 3h0aA-3j0cA:
undetectable		 3h0aA-3j0cA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j4j TRANSLATION
INITIATION FACTOR
IF-2

(Thermus
thermophilus) 		PF00009
(GTP_EFTU)
PF04760
(IF2_N)
PF11987
(IF-2) 		3 ILE A 149
PHE A 201
HIS A 167
 None
 0.75A 3h0aA-3j4jA:
undetectable		 3h0aA-3j4jA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k4y ISOPENTENYL
PHOSPHATE KINASE

(Methanocaldococcus
jannaschii) 		PF00696
(AA_kinase) 		3 ILE A 157
PHE A 125
HIS A  53
 None
 0.68A 3h0aA-3k4yA:
undetectable		 3h0aA-3k4yA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kzh PROBABLE SUGAR
KINASE

(Clostridium
perfringens) 		PF00294
(PfkB) 		3 ILE A 224
PHE A 214
HIS A 191
 None
 0.71A 3h0aA-3kzhA:
undetectable		 3h0aA-3kzhA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lat BIFUNCTIONAL
AUTOLYSIN

(Staphylococcus
epidermidis) 		PF01510
(Amidase_2) 		3 ILE A 120
PHE A 129
HIS A 181
 None
 0.69A 3h0aA-3latA:
undetectable		 3h0aA-3latA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lnl UPF0135 PROTEIN
SA1388

(Staphylococcus
aureus) 		PF01784
(NIF3) 		3 ILE A 310
PHE A 305
HIS A 330
 None
None
ZN  A 402 (-3.4A)
 0.71A 3h0aA-3lnlA:
undetectable		 3h0aA-3lnlA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lqc DNA POLYMERASE BETA

(Rattus
norvegicus) 		PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		3 ILE B 255
PHE B 235
HIS B 252
 None
 0.68A 3h0aA-3lqcB:
undetectable		 3h0aA-3lqcB:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lrn PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58

(Homo sapiens) 		PF11648
(RIG-I_C-RD) 		3 ILE A 862
PHE A 838
HIS A 871
 None
 0.58A 3h0aA-3lrnA:
undetectable		 3h0aA-3lrnA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdq EXOPOLYPHOSPHATASE

(Cytophaga
hutchinsonii) 		PF02541
(Ppx-GppA) 		3 ILE A 207
PHE A 118
HIS A 130
 None
 0.74A 3h0aA-3mdqA:
undetectable		 3h0aA-3mdqA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ov3 CURCUMIN SYNTHASE

(Curcuma longa) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		3 ILE A 132
PHE A 215
HIS A 165
 MLI  A 396 (-2.9A)
None
None
 0.75A 3h0aA-3ov3A:
undetectable		 3h0aA-3ov3A:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tex PROTECTIVE ANTIGEN

(Bacillus
anthracis) 		PF03495
(Binary_toxB)
PF07691
(PA14)
PF17475
(Binary_toxB_2)
PF17476
(Binary_toxB_3) 		3 ILE A 591
PHE A 531
HIS A 299
 None
 0.59A 3h0aA-3texA:
undetectable		 3h0aA-3texA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr7 URACIL-DNA
GLYCOSYLASE

(Coxiella
burnetii) 		PF03167
(UDG) 		3 ILE A  63
PHE A 205
HIS A 189
 None
 0.65A 3h0aA-3tr7A:
undetectable		 3h0aA-3tr7A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tx1 UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(Listeria
monocytogenes) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		3 ILE A 257
PHE A 222
HIS A 242
 None
 0.68A 3h0aA-3tx1A:
undetectable		 3h0aA-3tx1A:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ua4 PROTEIN ARGININE
N-METHYLTRANSFERASE
5

(Caenorhabditis
elegans) 		PF05185
(PRMT5)
PF17285
(PRMT5_TIM)
PF17286
(PRMT5_C) 		3 ILE A 629
PHE A 611
HIS A 707
 None
 0.58A 3h0aA-3ua4A:
undetectable		 3h0aA-3ua4A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwz D-LACTATE
DEHYDROGENASE
(FERMENTATIVE)

(Pseudomonas
aeruginosa) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		3 ILE A   3
PHE A  29
HIS A  23
 None
 0.76A 3h0aA-3wwzA:
undetectable		 3h0aA-3wwzA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zoq URACIL-DNA
GLYCOSYLASE

(Bacillus
subtilis) 		PF03167
(UDG) 		3 ILE A  61
PHE A 203
HIS A 187
 None
None
GOL  A1226 (-4.6A)
 0.73A 3h0aA-3zoqA:
undetectable		 3h0aA-3zoqA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zoq URACIL-DNA
GLYCOSYLASE

(Bacillus
subtilis) 		PF03167
(UDG) 		3 ILE A 162
PHE A 203
HIS A 187
 None
None
GOL  A1226 (-4.6A)
 0.60A 3h0aA-3zoqA:
undetectable		 3h0aA-3zoqA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ay2 PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX58

(Homo sapiens) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF11648
(RIG-I_C-RD) 		3 ILE A 862
PHE A 838
HIS A 871
 None
 0.67A 3h0aA-4ay2A:
undetectable		 3h0aA-4ay2A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bvt CYANURIC ACID
AMIDOHYDROLASE

(Pseudomonas sp.
ADP) 		PF09663
(Amido_AtzD_TrzD) 		3 ILE A  34
PHE A  80
HIS A  66
 None
 0.71A 3h0aA-4bvtA:
undetectable		 3h0aA-4bvtA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fcy TRANSPOSASE

(Escherichia
virus Mu) 		PF02316
(HTH_Tnp_Mu_1)
PF02914
(DDE_2)
PF09039
(HTH_Tnp_Mu_2)
PF09299
(Mu-transpos_C) 		3 ILE A 266
PHE A 318
HIS A 375
 None
 0.69A 3h0aA-4fcyA:
undetectable		 3h0aA-4fcyA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fgu LEGUMAIN

(Homo sapiens) 		PF01650
(Peptidase_C13) 		3 ILE A  56
PHE A 142
HIS A  51
 None
 0.59A 3h0aA-4fguA:
undetectable		 3h0aA-4fguA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g56 HSL7 PROTEIN

(Xenopus laevis) 		PF05185
(PRMT5)
PF17285
(PRMT5_TIM)
PF17286
(PRMT5_C) 		3 ILE A 134
PHE A 188
HIS A 136
 None
 0.75A 3h0aA-4g56A:
undetectable		 3h0aA-4g56A:
15.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4j5x RETINOIC ACID
RECEPTOR RXR-ALPHA,
NUCLEAR RECEPTOR
COACTIVATOR 1

(Homo sapiens) 		no annotation 3 ILE D 268
PHE D 313
HIS D 435
 None
 0.61A 3h0aA-4j5xD:
30.9		 3h0aA-4j5xD:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb3 HALOACID
DEHALOGENASE-LIKE
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF13419
(HAD_2) 		3 ILE A 179
PHE A 169
HIS A  41
 None
 0.71A 3h0aA-4jb3A:
undetectable		 3h0aA-4jb3A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jcm CYCLODEXTRIN
GLUCANOTRANSFERASE

([Bacillus]
clarkii) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG) 		3 ILE A  76
PHE A 109
HIS A 317
 None
 0.75A 3h0aA-4jcmA:
undetectable		 3h0aA-4jcmA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4knk BIFUNCTIONAL
AUTOLYSIN

(Staphylococcus
aureus) 		PF01510
(Amidase_2) 		3 ILE A 325
PHE A 334
HIS A 386
 None
 0.65A 3h0aA-4knkA:
undetectable		 3h0aA-4knkA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l5n URACIL-DNA
GLYCOSYLASE

(Human
alphaherpesvirus
1) 		PF03167
(UDG) 		3 ILE A  84
PHE A 225
HIS A 210
 None
 0.76A 3h0aA-4l5nA:
undetectable		 3h0aA-4l5nA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyk CYCLIC DI-GMP
PHOSPHODIESTERASE
YAHA

(Escherichia
coli) 		PF00563
(EAL) 		3 ILE A 248
PHE A 211
HIS A 253
 None
 0.68A 3h0aA-4lykA:
undetectable		 3h0aA-4lykA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyl URACIL-DNA
GLYCOSYLASE

(Gadus morhua) 		PF03167
(UDG) 		3 ILE A 141
PHE A 284
HIS A 268
 None
 0.73A 3h0aA-4lylA:
undetectable		 3h0aA-4lylA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m47 DNA POLYMERASE BETA

(Homo sapiens) 		PF10391
(DNA_pol_lambd_f)
PF14716
(HHH_8)
PF14791
(DNA_pol_B_thumb)
PF14792
(DNA_pol_B_palm) 		3 ILE A 255
PHE A 235
HIS A 252
 None
 0.76A 3h0aA-4m47A:
1.4		 3h0aA-4m47A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mkv RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN

(Pisum sativum) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		3 ILE A 301
PHE A 117
HIS A 310
 None
 0.75A 3h0aA-4mkvA:
undetectable		 3h0aA-4mkvA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n2z GH62
ARABINOFURANOSIDASE

(Podospora
anserina) 		PF03664
(Glyco_hydro_62) 		3 ILE A 289
PHE A 329
HIS A  60
 None
 0.74A 3h0aA-4n2zA:
undetectable		 3h0aA-4n2zA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ptf DNA POLYMERASE
EPSILON CATALYTIC
SUBUNIT A

(Saccharomyces
cerevisiae) 		PF00136
(DNA_pol_B)
PF03104
(DNA_pol_B_exo1) 		3 ILE A 879
PHE A 944
HIS A 557
 None
 0.74A 3h0aA-4ptfA:
undetectable		 3h0aA-4ptfA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pyt UDP-N-ACETYLENOLPYRU
VOYLGLUCOSAMINE
REDUCTASE

(unidentified) 		PF01565
(FAD_binding_4)
PF02873
(MurB_C) 		3 ILE A 262
PHE A 227
HIS A 247
 None
 0.66A 3h0aA-4pytA:
undetectable		 3h0aA-4pytA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rdy PARATHION HYDROLASE

(Vulcanisaeta
moutnovskia) 		PF02126
(PTE) 		3 ILE A 198
PHE A 186
HIS A 171
 None
None
CO  A 402 ( 3.1A)
 0.73A 3h0aA-4rdyA:
undetectable		 3h0aA-4rdyA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u63 DNA PHOTOLYASE

(Agrobacterium
fabrum) 		PF00875
(DNA_photolyase)
PF03441
(FAD_binding_7) 		3 ILE A 354
PHE A 306
HIS A 356
 None
 0.76A 3h0aA-4u63A:
undetectable		 3h0aA-4u63A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqm URACIL-DNA
GLYCOSYLASE

(Deinococcus
radiodurans) 		PF03167
(UDG) 		3 ILE A  79
PHE A 221
HIS A 206
 None
 0.68A 3h0aA-4uqmA:
undetectable		 3h0aA-4uqmA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqm URACIL-DNA
GLYCOSYLASE

(Deinococcus
radiodurans) 		PF03167
(UDG) 		3 ILE A 181
PHE A 221
HIS A 206
 None
 0.59A 3h0aA-4uqmA:
undetectable		 3h0aA-4uqmA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wzh DIHYDROOROTATE
DEHYDROGENASE

(Leishmania
braziliensis) 		PF01180
(DHO_dh) 		3 ILE A  97
PHE A  77
HIS A 160
 None
 0.75A 3h0aA-4wzhA:
undetectable		 3h0aA-4wzhA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xj5 CYCLIC AMP-GMP
SYNTHASE

(Vibrio cholerae) 		no annotation 3 ILE A 149
PHE A  47
HIS A 151
 None
 0.70A 3h0aA-4xj5A:
undetectable		 3h0aA-4xj5A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xuk PUTATIVE HYDROLASE

(Acinetobacter
sp. NBRC 100985) 		PF00753
(Lactamase_B) 		3 ILE A 263
PHE A 298
HIS A 244
 None
None
ZN  A 402 (-3.3A)
 0.74A 3h0aA-4xukA:
undetectable		 3h0aA-4xukA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z8z UNCHARACTERIZED
PROTEIN

(Ruminiclostridium
thermocellum) 		no annotation 3 ILE A 255
PHE A 283
HIS A 197
 None
 0.75A 3h0aA-4z8zA:
undetectable		 3h0aA-4z8zA:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zvc DIGUANYLATE CYCLASE
DOSC

(Escherichia
coli) 		no annotation 3 ILE A 242
PHE A 217
HIS A 237
 None
 0.73A 3h0aA-4zvcA:
undetectable		 3h0aA-4zvcA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c70 GLUCURONIDASE

(Aspergillus
oryzae) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		3 ILE A  52
PHE A  21
HIS A  59
 None
 0.62A 3h0aA-5c70A:
undetectable		 3h0aA-5c70A:
19.48