SIMILAR PATTERNS OF AMINO ACIDS FOR 3GV1_B_BEZB303
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bt2 | PROTEIN (CATECHOLOXIDASE) (Ipomoea batatas) |
PF00264(Tyrosinase)PF12142(PPO1_DWL) | 4 | LEU A 307ALA A 32VAL A 31PRO A 30 | None | 1.16A | 3gv1B-1bt2A:undetectable | 3gv1B-1bt2A:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ddb | PROTEIN (BID) (Mus musculus) |
PF06393(BID) | 4 | LEU A 38ALA A 160VAL A 159PRO A 164 | None | 1.15A | 3gv1B-1ddbA:undetectable | 3gv1B-1ddbA:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1djp | GLUTAMINASE-ASPARAGINASE (Pseudomonas sp.7A) |
PF00710(Asparaginase) | 4 | LEU A1330ALA A1248VAL A1224PRO A1222 | None | 1.01A | 3gv1B-1djpA:undetectable | 3gv1B-1djpA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gll | GLYCEROL KINASE (Escherichiacoli) |
no annotation | 4 | LEU Y 191ALA Y 186VAL Y 217PRO Y 215 | None | 0.93A | 3gv1B-1gllY:0.0 | 3gv1B-1gllY:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hcu | ALPHA-1,2-MANNOSIDASE (Trichodermareesei) |
PF01532(Glyco_hydro_47) | 4 | LEU A 181ALA A 147VAL A 159PRO A 157 | None | 1.03A | 3gv1B-1hcuA:undetectable | 3gv1B-1hcuA:13.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hyq | CELL DIVISIONINHIBITOR (MIND-1) (Archaeoglobusfulgidus) |
PF01656(CbiA) | 4 | LEU A 92ALA A 39VAL A 37PRO A 84 | None | 0.98A | 3gv1B-1hyqA:0.0 | 3gv1B-1hyqA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jdi | L-RIBULOSE 5PHOSPHATE4-EPIMERASE (Escherichiacoli) |
PF00596(Aldolase_II) | 4 | LEU A 167ALA A 194VAL A 193PRO A 112 | None | 1.13A | 3gv1B-1jdiA:0.0 | 3gv1B-1jdiA:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jg3 | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASE (Pyrococcusfuriosus) |
PF01135(PCMT) | 4 | LEU A 175ALA A 168VAL A 189PRO A 188 | None | 1.15A | 3gv1B-1jg3A:undetectable | 3gv1B-1jg3A:23.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jj7 | PEPTIDE TRANSPORTERTAP1 (Homo sapiens) |
PF00005(ABC_tran) | 4 | LEU A 673ALA A 669VAL A 584PRO A 588 | None | 1.10A | 3gv1B-1jj7A:0.0 | 3gv1B-1jj7A:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kr5 | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASE (Homo sapiens) |
PF01135(PCMT) | 4 | LEU A 168ALA A 161VAL A 182PRO A 181 | None | 1.11A | 3gv1B-1kr5A:undetectable | 3gv1B-1kr5A:21.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ltm | 36 KDA SOLUBLE LYTICTRANSGLYCOSYLASE (Escherichiacoli) |
PF13406(SLT_2) | 4 | LEU A 315ALA A 272VAL A 271PRO A 330 | None | 1.05A | 3gv1B-1ltmA:undetectable | 3gv1B-1ltmA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qhg | ATP-DEPENDENTHELICASE PCRA (Geobacillusstearothermophilus) |
PF00580(UvrD-helicase)PF13361(UvrD_C) | 4 | LEU A 570ALA A 355VAL A 575PRO A 573 | None | 1.12A | 3gv1B-1qhgA:undetectable | 3gv1B-1qhgA:11.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qu0 | LAMININ ALPHA2 CHAIN (Mus musculus) |
PF02210(Laminin_G_2) | 4 | LEU A2974ALA A2948VAL A2949PRO A3059 | None | 1.04A | 3gv1B-1qu0A:undetectable | 3gv1B-1qu0A:22.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1r18 | PROTEIN-L-ISOASPARTATE(D-ASPARTATE)-O-METHYLTRANSFERASE (Drosophilamelanogaster) |
PF01135(PCMT) | 4 | LEU A 174ALA A 167VAL A 188PRO A 187 | None | 1.02A | 3gv1B-1r18A:undetectable | 3gv1B-1r18A:22.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s16 | TOPOISOMERASE IVSUBUNIT B (Escherichiacoli) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 4 | LEU A1035ALA A1121VAL A1019PRO A1023 | None | 1.07A | 3gv1B-1s16A:undetectable | 3gv1B-1s16A:14.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uc8 | LYSINE BIOSYNTHESISENZYME (Thermusthermophilus) |
PF08443(RimK) | 4 | LEU A 46ALA A 52VAL A 76PRO A 75 | None | 1.15A | 3gv1B-1uc8A:1.6 | 3gv1B-1uc8A:17.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v5x | PHOSPHORIBOSYLANTHRANILATE ISOMERASE (Thermusthermophilus) |
PF00697(PRAI) | 4 | LEU A 68ALA A 79VAL A 99PRO A 98 | None | 1.17A | 3gv1B-1v5xA:undetectable | 3gv1B-1v5xA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x7p | RRNAMETHYLTRANSFERASE (Streptomycesviridochromogenes) |
PF00588(SpoU_methylase) | 4 | LEU A 230ALA A 158VAL A 185PRO A 188 | None | 1.24A | 3gv1B-1x7pA:undetectable | 3gv1B-1x7pA:18.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bn8 | CELL DIVISIONACTIVATOR CEDA (Escherichiacoli) |
PF10729(CedA) | 4 | LEU A 61ALA A 52VAL A 51PRO A 64 | None | 1.21A | 3gv1B-2bn8A:undetectable | 3gv1B-2bn8A:24.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c4m | GLYCOGENPHOSPHORYLASE (Corynebacteriumcallunae) |
PF00343(Phosphorylase) | 4 | LEU A 83ALA A 39VAL A 12PRO A 8 | None | 1.14A | 3gv1B-2c4mA:undetectable | 3gv1B-2c4mA:9.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d7i | POLYPEPTIDEN-ACETYLGALACTOSAMINYLTRANSFERASE 10 (Homo sapiens) |
PF00535(Glycos_transf_2)PF00652(Ricin_B_lectin) | 4 | LEU A 247ALA A 323VAL A 262PRO A 264 | None | 1.00A | 3gv1B-2d7iA:undetectable | 3gv1B-2d7iA:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dc0 | PROBABLE AMIDASE (Thermusthermophilus) |
PF01425(Amidase) | 4 | LEU A 260ALA A 401VAL A 408PRO A 399 | None | 1.08A | 3gv1B-2dc0A:undetectable | 3gv1B-2dc0A:14.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ddu | REELIN (Mus musculus) |
no annotation | 4 | LEU A1543ALA A1375VAL A1301PRO A1412 | None | 1.23A | 3gv1B-2dduA:undetectable | 3gv1B-2dduA:14.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dgw | PROBABLE RNA-BINDINGPROTEIN 19 (Homo sapiens) |
PF00076(RRM_1) | 4 | LEU A 298ALA A 349VAL A 346PRO A 319 | None | 1.07A | 3gv1B-2dgwA:undetectable | 3gv1B-2dgwA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dkk | CYTOCHROME P450 (Streptomycescoelicolor) |
PF00067(p450) | 4 | LEU A 134ALA A 158VAL A 159PRO A 156 | None | 1.23A | 3gv1B-2dkkA:undetectable | 3gv1B-2dkkA:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gf4 | PROTEIN VNG1086C (Halobacteriumsalinarum) |
PF01893(UPF0058) | 4 | LEU A 6ALA A 54VAL A 39PRO A 41 | None | 1.11A | 3gv1B-2gf4A:undetectable | 3gv1B-2gf4A:22.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hz7 | GLUTAMINYL-TRNASYNTHETASE (Deinococcusradiodurans) |
PF00749(tRNA-synt_1c)PF03950(tRNA-synt_1c_C) | 4 | LEU A 376ALA A 346VAL A 347PRO A 344 | None | 1.23A | 3gv1B-2hz7A:undetectable | 3gv1B-2hz7A:10.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iih | MOLYBDENUM COFACTORBIOSYNTHESIS PROTEINC (Thermusthermophilus) |
PF01967(MoaC) | 4 | LEU A 34ALA A 41VAL A 47PRO A 52 | None | 1.24A | 3gv1B-2iihA:undetectable | 3gv1B-2iihA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q4p | PROTEIN RS21-C6 (Mus musculus) |
PF12643(MazG-like) | 4 | LEU A 103ALA A 107VAL A 112PRO A 115 | None | 1.15A | 3gv1B-2q4pA:undetectable | 3gv1B-2q4pA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w4e | MUTT/NUDIX FAMILYPROTEIN (Deinococcusradiodurans) |
PF00293(NUDIX) | 4 | LEU A 187ALA A 74VAL A 68PRO A 67 | None | 1.11A | 3gv1B-2w4eA:undetectable | 3gv1B-2w4eA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wxz | ANGIOTENSINOGEN (Rattusnorvegicus) |
PF00079(Serpin) | 4 | LEU A 150ALA A 77VAL A 80PRO A 102 | None | 1.23A | 3gv1B-2wxzA:undetectable | 3gv1B-2wxzA:13.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xkr | PUTATIVE CYTOCHROMEP450 142 (Mycobacteriumtuberculosis) |
PF00067(p450) | 4 | LEU A 113ALA A 136VAL A 137PRO A 134 | None | 1.17A | 3gv1B-2xkrA:undetectable | 3gv1B-2xkrA:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yvp | MUTT/NUDIX FAMILYPROTEIN (Thermusthermophilus) |
PF00293(NUDIX) | 4 | LEU A 169ALA A 55VAL A 49PRO A 48 | None | 1.23A | 3gv1B-2yvpA:undetectable | 3gv1B-2yvpA:19.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3al0 | GLUTAMYL-TRNA(GLN)AMIDOTRANSFERASESUBUNIT A (Thermotogamaritima) |
PF01425(Amidase) | 4 | LEU A 378ALA A 248VAL A 283PRO A 250 | None | 1.21A | 3gv1B-3al0A:undetectable | 3gv1B-3al0A:14.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cer | POSSIBLEEXOPOLYPHOSPHATASE-LIKE PROTEIN (Bifidobacteriumlongum) |
PF02541(Ppx-GppA) | 4 | LEU A 53ALA A 94VAL A 121PRO A 119 | None | 1.16A | 3gv1B-3cerA:undetectable | 3gv1B-3cerA:17.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cwv | DNA GYRASE, BSUBUNIT, TRUNCATED (Myxococcusxanthus) |
PF00204(DNA_gyraseB) | 4 | LEU A 33ALA A 106VAL A 14PRO A 18 | None | 1.00A | 3gv1B-3cwvA:undetectable | 3gv1B-3cwvA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d79 | PUTATIVEUNCHARACTERIZEDPROTEIN PH0734 (Pyrococcushorikoshii) |
PF01472(PUA)PF09183(DUF1947) | 4 | LEU A 101ALA A 136VAL A 126PRO A 134 | None | 0.80A | 3gv1B-3d79A:undetectable | 3gv1B-3d79A:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dkw | DNR PROTEIN (Pseudomonasaeruginosa) |
PF00027(cNMP_binding)PF13545(HTH_Crp_2) | 4 | LEU A 56ALA A 102VAL A 103PRO A 105 | None | 1.18A | 3gv1B-3dkwA:undetectable | 3gv1B-3dkwA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dkw | DNR PROTEIN (Pseudomonasaeruginosa) |
PF00027(cNMP_binding)PF13545(HTH_Crp_2) | 4 | LEU A 108ALA A 102VAL A 103PRO A 105 | None | 1.24A | 3gv1B-3dkwA:undetectable | 3gv1B-3dkwA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e23 | UNCHARACTERIZEDPROTEIN RPA2492 (Rhodopseudomonaspalustris) |
PF08241(Methyltransf_11) | 4 | LEU A 62ALA A 70VAL A 89PRO A 88 | None | 0.96A | 3gv1B-3e23A:undetectable | 3gv1B-3e23A:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e38 | TWO-DOMAIN PROTEINCONTAINING PREDICTEDPHP-LIKEMETAL-DEPENDENTPHOSPHOESTERASE (Bacteroidesvulgatus) |
PF16392(DUF5001) | 4 | LEU A 262ALA A 189VAL A 188PRO A 196 | None | 0.97A | 3gv1B-3e38A:undetectable | 3gv1B-3e38A:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f8t | PREDICTED ATPASEINVOLVED INREPLICATION CONTROL,CDC46/MCM FAMILY (Methanopyruskandleri) |
PF00493(MCM) | 4 | LEU A 46ALA A 89VAL A 92PRO A 94 | None | 0.98A | 3gv1B-3f8tA:undetectable | 3gv1B-3f8tA:11.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fv5 | DNA TOPOISOMERASE 4SUBUNIT B (Escherichiacoli) |
PF02518(HATPase_c) | 4 | LEU A 35ALA A 121VAL A 19PRO A 23 | None | 1.00A | 3gv1B-3fv5A:undetectable | 3gv1B-3fv5A:21.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gv1 | DISULFIDEINTERCHANGE PROTEIN (Neisseriagonorrhoeae) |
PF13098(Thioredoxin_2) | 4 | LEU A 125ALA A 141VAL A 236PRO A 238 | None | 0.11A | 3gv1B-3gv1A:29.9 | 3gv1B-3gv1A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ll7 | PUTATIVEMETHYLTRANSFERASE (Porphyromonasgingivalis) |
no annotation | 4 | LEU A 219ALA A 204VAL A 166PRO A 168 | None | 1.20A | 3gv1B-3ll7A:undetectable | 3gv1B-3ll7A:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lps | TOPOISOMERASE IVSUBUNIT B (Xanthomonasoryzae) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 4 | LEU A 79ALA A 165VAL A 63PRO A 67 | None | 1.10A | 3gv1B-3lpsA:undetectable | 3gv1B-3lpsA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3or2 | SULFITE REDCUTASESUBUNIT BETA (Desulfovibriogigas) |
PF00037(Fer4)PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 4 | LEU B 218ALA B 227VAL B 228PRO B 225 | None | 1.24A | 3gv1B-3or2B:undetectable | 3gv1B-3or2B:16.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p7x | PROBABLE THIOLPEROXIDASE (Staphylococcusaureus) |
PF08534(Redoxin) | 4 | LEU A 13ALA A 129VAL A 51PRO A 53 | SO4 A 165 (-3.7A)NoneNoneNone | 0.77A | 3gv1B-3p7xA:3.8 | 3gv1B-3p7xA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qpf | PUTATIVEUNCHARACTERIZEDPROTEIN (Streptococcuspneumoniae) |
PF06824(Glyco_hydro_125) | 4 | LEU A 361ALA A 343VAL A 397PRO A 400 | None | 1.16A | 3gv1B-3qpfA:undetectable | 3gv1B-3qpfA:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qt3 | PUTATIVEUNCHARACTERIZEDPROTEIN CPE0426 (Clostridiumperfringens) |
PF06824(Glyco_hydro_125) | 4 | LEU A 361ALA A 343VAL A 397PRO A 400 | None | 1.11A | 3gv1B-3qt3A:undetectable | 3gv1B-3qt3A:16.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r77 | PROBABLEISOCHORISMATASE (Pseudomonasfluorescens) |
PF00857(Isochorismatase) | 4 | LEU A 145ALA A 74VAL A 73PRO A 72 | None | 1.24A | 3gv1B-3r77A:undetectable | 3gv1B-3r77A:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ucq | AMYLOSUCRASE (Deinococcusgeothermalis) |
PF00128(Alpha-amylase) | 4 | LEU A 531ALA A 502VAL A 546PRO A 542 | None | 1.21A | 3gv1B-3ucqA:undetectable | 3gv1B-3ucqA:11.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uif | SULFONATE ABCTRANSPORTER,PERIPLASMICSULFONATE-BINDINGPROTEIN SSUA (Methylobacillusflagellatus) |
PF09084(NMT1) | 4 | LEU A 184ALA A 145VAL A 175PRO A 177 | NoneNoneNoneSO4 A 501 (-4.1A) | 1.20A | 3gv1B-3uifA:undetectable | 3gv1B-3uifA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vxc | PUTATIVESUGAR-BINDINGLIPOPROTEIN (Streptomycesthermoviolaceus) |
PF01547(SBP_bac_1) | 4 | LEU A 172ALA A 191VAL A 193PRO A 195 | None | 1.06A | 3gv1B-3vxcA:undetectable | 3gv1B-3vxcA:15.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w04 | DWARF 88 ESTERASE (Oryza sativa) |
PF12697(Abhydrolase_6) | 4 | LEU A 229ALA A 213VAL A 214PRO A 211 | None | 1.24A | 3gv1B-3w04A:1.4 | 3gv1B-3w04A:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zby | P450 HEME-THIOLATEPROTEIN (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 4 | LEU A 116ALA A 139VAL A 140PRO A 137 | None | 1.15A | 3gv1B-3zbyA:undetectable | 3gv1B-3zbyA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zkb | DNA GYRASE SUBUNIT B (Mycobacteriumtuberculosis) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 4 | LEU A 45ALA A 130VAL A 26PRO A 30 | None | 1.13A | 3gv1B-3zkbA:undetectable | 3gv1B-3zkbA:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c0r | PUTATIVE AMINO ACIDBINDING PROTEIN (Streptococcusmutans) |
PF00497(SBP_bac_3) | 4 | LEU A 220ALA A 87VAL A 192PRO A 85 | None | 1.18A | 3gv1B-4c0rA:undetectable | 3gv1B-4c0rA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dut | NUCLEOSIDEDIPHOSPHATE KINASE (Burkholderiathailandensis) |
PF00334(NDK) | 4 | LEU A 7ALA A 36VAL A 138PRO A 134 | None | 1.22A | 3gv1B-4dutA:undetectable | 3gv1B-4dutA:25.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4g | METHYLMALONATE-SEMIALDEHYDEDEHYDROGENASE (Sinorhizobiummeliloti) |
PF00171(Aldedh) | 4 | LEU A 401ALA A 392VAL A 288PRO A 287 | None | 1.18A | 3gv1B-4e4gA:undetectable | 3gv1B-4e4gA:14.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4em7 | DNA TOPOISOMERASEIV, B SUBUNIT (Streptococcuspneumoniae) |
PF02518(HATPase_c) | 4 | LEU A 44ALA A 129VAL A 25PRO A 29 | None | 1.10A | 3gv1B-4em7A:undetectable | 3gv1B-4em7A:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eq9 | ABC TRANSPORTERSUBSTRATE-BINDINGPROTEIN-AMINO ACIDTRANSPORT (Streptococcuspneumoniae) |
PF00497(SBP_bac_3) | 4 | LEU A 256ALA A 122VAL A 228PRO A 120 | None | 1.03A | 3gv1B-4eq9A:undetectable | 3gv1B-4eq9A:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hxw | DNA GYRASE SUBUNIT B (Enterococcusfaecalis) |
PF02518(HATPase_c) | 4 | LEU A 48ALA A 134VAL A 29PRO A 33 | None | 1.12A | 3gv1B-4hxwA:undetectable | 3gv1B-4hxwA:21.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hym | TOPOISOMERASE IV,SUBUNIT B (Francisellatularensis) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 4 | LEU A 34ALA A 120VAL A 18PRO A 22 | None | 1.05A | 3gv1B-4hymA:undetectable | 3gv1B-4hymA:18.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hz5 | DNA TOPOISOMERASEIV, B SUBUNIT (Enterococcusfaecalis) |
PF02518(HATPase_c) | 4 | LEU A 42ALA A 127VAL A 23PRO A 27 | None | 1.20A | 3gv1B-4hz5A:undetectable | 3gv1B-4hz5A:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4iv9 | TRYPTOPHAN2-MONOOXYGENASE (Pseudomonassavastanoi) |
PF01593(Amino_oxidase) | 4 | LEU A 182ALA A 193VAL A 173PRO A 175 | None | 1.20A | 3gv1B-4iv9A:undetectable | 3gv1B-4iv9A:12.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jyp | HYDROLASE,ALPHA/BETA FOLDFAMILY PROTEIN (Arabidopsisthaliana) |
PF12697(Abhydrolase_6) | 4 | LEU A 178ALA A 161VAL A 162PRO A 159 | None | 1.22A | 3gv1B-4jypA:0.8 | 3gv1B-4jypA:20.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l7v | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASE (Vibrio cholerae) |
PF01135(PCMT) | 4 | LEU A 158ALA A 151VAL A 172PRO A 171 | None | 1.16A | 3gv1B-4l7vA:undetectable | 3gv1B-4l7vA:19.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o29 | PROTEIN-L-ISOASPARTATEO-METHYLTRANSFERASE (Pyrobaculumaerophilum) |
PF01135(PCMT) | 4 | LEU A 159ALA A 152VAL A 173PRO A 172 | None | 1.12A | 3gv1B-4o29A:undetectable | 3gv1B-4o29A:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oib | INTERCELLULARADHESION MOLECULE 5 (Homo sapiens) |
PF03921(ICAM_N) | 4 | LEU A 190ALA A 156VAL A 103PRO A 102 | None | 1.10A | 3gv1B-4oibA:undetectable | 3gv1B-4oibA:17.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqj | PKS (Streptomycesalbus) |
PF00109(ketoacyl-synt)PF02801(Ketoacyl-synt_C)PF16197(KAsynt_C_assoc) | 4 | LEU A 269ALA A 21VAL A 278PRO A 447 | None | 1.00A | 3gv1B-4oqjA:undetectable | 3gv1B-4oqjA:10.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiu | NITRONATEMONOOXYGENASE FAMILYPROTEIN (Pseudomonasaeruginosa) |
PF03060(NMO) | 4 | LEU A 9ALA A 235VAL A 214PRO A 212 | None | 1.17A | 3gv1B-4qiuA:undetectable | 3gv1B-4qiuA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r9n | LMO0547 PROTEIN (Listeriamonocytogenes) |
PF04198(Sugar-bind) | 4 | LEU A 264ALA A 205VAL A 275PRO A 273 | None | 1.00A | 3gv1B-4r9nA:undetectable | 3gv1B-4r9nA:18.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rlt | (3R)-HYDROXYACYL-ACPDEHYDRATASE SUBUNITHADB (Mycobacteriumtuberculosis) |
PF01575(MaoC_dehydratas) | 4 | LEU B 102ALA B 100VAL B 93PRO B 92 | None | 1.11A | 3gv1B-4rltB:undetectable | 3gv1B-4rltB:22.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tnu | ASPARTOACYLASE (Homo sapiens) |
PF04952(AstE_AspA) | 4 | LEU A 69ALA A 57VAL A 58PRO A 55 | None | 1.14A | 3gv1B-4tnuA:undetectable | 3gv1B-4tnuA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4url | DNA TOPOISOMERASEIV, B SUBUNIT (Staphylococcusaureus) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 4 | LEU A 42ALA A 127VAL A 23PRO A 27 | None | 1.08A | 3gv1B-4urlA:undetectable | 3gv1B-4urlA:15.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4urn | DNA TOPOISOMERASEIV, B SUBUNIT (Staphylococcusaureus) |
PF02518(HATPase_c) | 4 | LEU A 42ALA A 127VAL A 23PRO A 27 | None | 1.14A | 3gv1B-4urnA:undetectable | 3gv1B-4urnA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x84 | RIBOSE-5-PHOSPHATEISOMERASE A (Pseudomonasaeruginosa) |
PF06026(Rib_5-P_isom_A) | 4 | LEU A 43ALA A 53VAL A 71PRO A 70 | None | 1.13A | 3gv1B-4x84A:undetectable | 3gv1B-4x84A:20.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xjc | DEOXYCYTIDINETRIPHOSPHATEDEAMINASE (Bacillushalodurans) |
PF00692(dUTPase) | 4 | LEU A 17ALA A 93VAL A 114PRO A 116 | NoneNoneTTP A 201 ( 4.0A)None | 0.94A | 3gv1B-4xjcA:undetectable | 3gv1B-4xjcA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ys8 | 2-C-METHYL-D-ERYTHRITOL 4-PHOSPHATECYTIDYLYLTRANSFERASE (Burkholderiathailandensis) |
PF01128(IspD) | 4 | LEU A 211ALA A 140VAL A 139PRO A 138 | None | 1.23A | 3gv1B-4ys8A:1.4 | 3gv1B-4ys8A:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zze | SUGAR BINDINGPROTEIN OF ABCTRANSPORTER SYSTEM (Bifidobacteriumanimalis) |
PF01547(SBP_bac_1) | 4 | LEU A 354ALA A 163VAL A 327PRO A 161 | None | 0.80A | 3gv1B-4zzeA:undetectable | 3gv1B-4zzeA:15.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5amw | FRA A 2 ALLERGEN (Fragaria xananassa) |
PF00407(Bet_v_1) | 4 | LEU A 147ALA A 38VAL A 39PRO A 36 | None | 1.04A | 3gv1B-5amwA:undetectable | 3gv1B-5amwA:19.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b04 | PROBABLE TRANSLATIONINITIATION FACTOREIF-2B SUBUNIT GAMMA (Schizosaccharomycespombe) |
PF00483(NTP_transferase) | 4 | LEU E 65ALA E 414VAL E 432PRO E 53 | None | 1.04A | 3gv1B-5b04E:undetectable | 3gv1B-5b04E:14.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bs5 | 3-PHOSPHOSHIKIMATE1-CARBOXYVINYLTRANSFERASE (Acinetobacterbaumannii) |
PF00275(EPSP_synthase) | 4 | LEU A 635ALA A 628VAL A 625PRO A 621 | None | 1.13A | 3gv1B-5bs5A:undetectable | 3gv1B-5bs5A:16.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5c92 | KELCHDOMAIN-CONTAININGPROTEIN (Colletotrichumgraminicola) |
PF01344(Kelch_1)PF09118(DUF1929) | 4 | LEU A 340ALA A 475VAL A 474PRO A 472 | None | 1.24A | 3gv1B-5c92A:undetectable | 3gv1B-5c92A:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fw4 | DYE-DECOLORIZINGPEROXIDASE TFU_3078 (Thermobifidafusca) |
PF04261(Dyp_perox) | 4 | LEU A 384ALA A 76VAL A 103PRO A 33 | None | 1.11A | 3gv1B-5fw4A:undetectable | 3gv1B-5fw4A:15.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gtq | LUCIFERINREGENERATING ENZYME (Photinuspyralis) |
PF08450(SGL) | 4 | LEU A 131ALA A 157VAL A 136PRO A 135 | None | 1.23A | 3gv1B-5gtqA:undetectable | 3gv1B-5gtqA:18.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gw7 | GLUCOSIDASE YGJK (Escherichiacoli) |
PF01204(Trehalase) | 4 | LEU A 224ALA A 216VAL A 203PRO A 202 | None | 1.23A | 3gv1B-5gw7A:undetectable | 3gv1B-5gw7A:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ik8 | LAMININ SUBUNITALPHA-2 (Mus musculus) |
PF00054(Laminin_G_1)PF02210(Laminin_G_2) | 4 | LEU A2974ALA A2948VAL A2949PRO A3059 | None | 1.03A | 3gv1B-5ik8A:undetectable | 3gv1B-5ik8A:17.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j5p | DNA TOPOISOMERASE 4SUBUNIT B (Streptococcuspneumoniae) |
PF00204(DNA_gyraseB)PF02518(HATPase_c) | 4 | LEU A 44ALA A 129VAL A 25PRO A 29 | None | 1.14A | 3gv1B-5j5pA:undetectable | 3gv1B-5j5pA:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ks8 | PYRUVATE CARBOXYLASESUBUNIT BETA (Methylobacillusflagellatus) |
PF00364(Biotin_lipoyl)PF00682(HMGL-like)PF02436(PYC_OADA) | 4 | LEU C 304ALA C 348VAL C 327PRO C 325 | None | 1.22A | 3gv1B-5ks8C:undetectable | 3gv1B-5ks8C:12.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5myu | TYPE VI SECRETIONSYSTEM PROTEIN IMPC (Vibrio cholerae) |
PF05943(VipB) | 4 | LEU A 206ALA A 240VAL A 193PRO A 195 | None | 1.08A | 3gv1B-5myuA:undetectable | 3gv1B-5myuA:16.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nqa | POLYPEPTIDEN-ACETYLGALACTOSAMINYLTRANSFERASE 4 (Homo sapiens) |
no annotation | 4 | LEU A 237ALA A 315VAL A 252PRO A 254 | None | 1.02A | 3gv1B-5nqaA:undetectable | 3gv1B-5nqaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yh0 | DRFAM20C1 (Danio rerio) |
no annotation | 4 | LEU A 453ALA A 365VAL A 305PRO A 304 | None | 1.15A | 3gv1B-5yh0A:undetectable | 3gv1B-5yh0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yh3 | EXTRACELLULARSERINE/THREONINEPROTEIN KINASEFAM20C (Homo sapiens) |
no annotation | 4 | LEU C 477ALA C 389VAL C 329PRO C 328 | None | 1.08A | 3gv1B-5yh3C:undetectable | 3gv1B-5yh3C:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z9s | GLYCOSYL HYDROLASEFAMILY 3 PROTEIN (Bifidobacteriumlongum) |
no annotation | 4 | LEU A 541ALA A 513VAL A 408PRO A 410 | None | 1.14A | 3gv1B-5z9sA:undetectable | 3gv1B-5z9sA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ams | BETA SLIDING CLAMP (Pseudomonasaeruginosa) |
no annotation | 4 | LEU A 284ALA A 348VAL A 362PRO A 364 | None | 1.23A | 3gv1B-6amsA:undetectable | 3gv1B-6amsA:15.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ap6 | PROBABLESTRIGOLACTONEESTERASE DAD2 (Petunia xhybrida) |
no annotation | 4 | LEU A 178ALA A 162VAL A 163PRO A 160 | None | 1.21A | 3gv1B-6ap6A:1.2 | 3gv1B-6ap6A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f0k | FE-S-CLUSTER-CONTAINING HYDROGENASE (Rhodothermusmarinus) |
no annotation | 4 | LEU B 635ALA B 607VAL B 646PRO B 645 | None | 1.20A | 3gv1B-6f0kB:undetectable | 3gv1B-6f0kB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gk6 | - (-) |
no annotation | 4 | LEU A 129ALA A 152VAL A 153PRO A 150 | None | 1.14A | 3gv1B-6gk6A:undetectable | 3gv1B-6gk6A:undetectable |