SIMILAR PATTERNS OF AMINO ACIDS FOR 3GSS_B_EAAB211_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bud PROTEIN (ACUTOLYSIN
A)

(Deinagkistrodon
acutus) 		PF01421
(Reprolysin) 		4 VAL A 150
ILE A  49
TYR A  44
THR A  41
 None
 0.99A 3gssB-1budA:
undetectable		 3gssB-1budA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c0a ASPARTYL TRNA
SYNTHETASE

(Escherichia
coli) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon)
PF02938
(GAD) 		4 PHE A 304
VAL A 302
ILE A 380
THR A 293
 AMP  A 800 (-4.7A)
None
None
None
 0.99A 3gssB-1c0aA:
undetectable		 3gssB-1c0aA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f3l PROTEIN ARGININE
METHYLTRANSFERASE
PRMT3

(Rattus
norvegicus) 		PF06325
(PrmA) 		4 TYR A 330
PHE A 334
ILE A 226
TYR A 221
 None
None
None
SAH  A 529 (-3.5A)
 0.77A 3gssB-1f3lA:
0.0		 3gssB-1f3lA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fcp PROTEIN (FERRIC
HYDROXAMATE UPTAKE
RECEPTOR)

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		4 TYR A 140
VAL A 136
THR A  73
GLY A 147
 None
 0.99A 3gssB-1fcpA:
undetectable		 3gssB-1fcpA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fnn CELL DIVISION
CONTROL PROTEIN 6

(Pyrobaculum
aerophilum) 		PF09079
(Cdc6_C)
PF13401
(AAA_22) 		4 VAL A  58
TYR A 192
THR A 193
GLY A  55
 ADP  A 398 (-3.7A)
ADP  A 398 (-4.6A)
None
ADP  A 398 (-3.3A)
 0.96A 3gssB-1fnnA:
undetectable		 3gssB-1fnnA:
19.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 TYR A   7
PHE A   8
ILE A 104
TYR A 108
THR A 109
 None
GSH  A 504 (-4.7A)
None
None
None
 0.65A 3gssB-1lbkA:
36.3		 3gssB-1lbkA:
97.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
PHE A   8
VAL A  10
ILE A 104
 None
GSH  A 504 (-4.7A)
None
None
 0.50A 3gssB-1lbkA:
36.3		 3gssB-1lbkA:
97.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nvm 4-HYDROXY-2-OXOVALER
ATE ALDOLASE

(Pseudomonas sp.
CF600) 		PF00682
(HMGL-like)
PF07836
(DmpG_comm) 		4 ILE A  35
TYR A  27
THR A  28
GLY A  19
 None
None
SO4  A3512 (-4.0A)
None
 0.96A 3gssB-1nvmA:
0.0		 3gssB-1nvmA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oki BETA CRYSTALLIN B1

(Homo sapiens) 		PF00030
(Crystall) 		4 VAL A  95
ILE A 114
THR A 191
GLY A  98
 None
 1.00A 3gssB-1okiA:
undetectable		 3gssB-1okiA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pz3 ALPHA-L-ARABINOFURAN
OSIDASE

(Geobacillus
stearothermophilus) 		PF06964
(Alpha-L-AF_C) 		4 VAL A 413
ILE A  23
TYR A  24
GLY A 383
 None
 0.79A 3gssB-1pz3A:
0.0		 3gssB-1pz3A:
18.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tu7 GLUTATHIONE
S-TRANSFERASE 2

(Onchocerca
volvulus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
PHE A   8
TYR A 106
GLY A 204
 None
GSH  A1001 (-4.8A)
None
None
 0.40A 3gssB-1tu7A:
30.9		 3gssB-1tu7A:
41.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1tu7 GLUTATHIONE
S-TRANSFERASE 2

(Onchocerca
volvulus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 106
TYR A   7
THR A   6
GLY A  12
 None
 0.78A 3gssB-1tu7A:
30.9		 3gssB-1tu7A:
41.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uzr RIBONUCLEOTIDE
REDUCTASE R2-2 SMALL
SUBUNIT

(Mycobacterium
tuberculosis) 		PF00268
(Ribonuc_red_sm) 		4 TYR A 110
PHE A  65
ILE A 194
GLY A 170
 None
 0.87A 3gssB-1uzrA:
undetectable		 3gssB-1uzrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xqp 8-OXOGUANINE DNA
GLYCOSYLASE

(Pyrobaculum
aerophilum) 		PF09171
(AGOG) 		4 PHE A  76
VAL A  38
ILE A 148
GLY A  47
 None
 0.75A 3gssB-1xqpA:
undetectable		 3gssB-1xqpA:
24.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7z HUMAN COXSACKIEVIRUS
A21

(Enterovirus C) 		PF00073
(Rhv) 		4 PHE 3  82
ILE 3 197
TYR 3 193
THR 3 195
 None
 0.91A 3gssB-1z7z3:
undetectable		 3gssB-1z7z3:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2amc PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN

(Thermus
thermophilus) 		PF01409
(tRNA-synt_2d) 		4 TYR A 307
PHE A 291
VAL A 294
THR A 179
 None
 0.83A 3gssB-2amcA:
undetectable		 3gssB-2amcA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gcu PUTATIVE
HYDROXYACYLGLUTATHIO
NE HYDROLASE 3

(Arabidopsis
thaliana) 		PF00753
(Lactamase_B) 		4 TYR A  29
PHE A 150
ILE A 157
GLY A 152
 None
None
EDO  A2003 (-4.9A)
None
 1.00A 3gssB-2gcuA:
undetectable		 3gssB-2gcuA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmn METALLO-BETA-LACTAMA
SE

(Bradyrhizobium
diazoefficiens) 		PF00753
(Lactamase_B) 		4 VAL A 245
ILE A  55
THR A  71
GLY A 240
 None
 0.92A 3gssB-2gmnA:
undetectable		 3gssB-2gmnA:
22.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 PHE A   8
VAL A  10
TYR A 106
THR A 103
GLY A 203
 GTS  A 208 (-4.7A)
None
None
None
None
 1.12A 3gssB-2gsrA:
35.4		 3gssB-2gsrA:
82.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		6 TYR A   7
PHE A   8
VAL A  10
TYR A 106
THR A 107
GLY A 203
 GTS  A 208 (-4.5A)
GTS  A 208 (-4.7A)
None
None
None
None
 0.28A 3gssB-2gsrA:
35.4		 3gssB-2gsrA:
82.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 106
TYR A   7
THR A   6
GLY A  12
 None
GTS  A 208 (-4.5A)
None
None
 0.73A 3gssB-2gsrA:
35.4		 3gssB-2gsrA:
82.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 VAL A  10
ILE A 105
TYR A 106
THR A 107
 None
 0.91A 3gssB-2gsrA:
35.4		 3gssB-2gsrA:
82.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gup ROK FAMILY PROTEIN

(Streptococcus
pneumoniae) 		PF00480
(ROK) 		4 TYR A  78
VAL A  76
ILE A  30
GLY A   9
 None
 0.82A 3gssB-2gupA:
undetectable		 3gssB-2gupA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hau SEROTRANSFERRIN

(Homo sapiens) 		PF00405
(Transferrin) 		4 ILE A 130
TYR A 319
THR A 321
GLY A  65
 None
 1.01A 3gssB-2hauA:
undetectable		 3gssB-2hauA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j8x URACIL-DNA
GLYCOSYLASE

(Human
gammaherpesvirus
4) 		PF03167
(UDG) 		4 TYR A  93
VAL A 105
ILE A 118
GLY A 135
 None
 1.00A 3gssB-2j8xA:
undetectable		 3gssB-2j8xA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jhq URACIL
DNA-GLYCOSYLASE

(Vibrio cholerae) 		PF03167
(UDG) 		4 TYR A  66
VAL A  79
ILE A  92
GLY A 109
 None
 0.93A 3gssB-2jhqA:
undetectable		 3gssB-2jhqA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jz0 PROTEIN DOUBLESEX

(Drosophila
melanogaster) 		PF08828
(DSX_dimer) 		4 TYR A  12
PHE A   9
VAL A   8
GLY A   5
 None
 1.00A 3gssB-2jz0A:
undetectable		 3gssB-2jz0A:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2msk NITROGEN REGULATION
PROTEIN NR(I)

(Salmonella
enterica) 		PF00072
(Response_reg) 		4 PHE A  33
VAL A   9
ILE A  69
GLY A  36
 None
 0.90A 3gssB-2mskA:
undetectable		 3gssB-2mskA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3e DIAMINOPIMELATE
DECARBOXYLASE

(Aquifex
aeolicus) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 TYR A  51
ILE A 212
TYR A 215
GLY A 243
 None
 0.92A 3gssB-2p3eA:
undetectable		 3gssB-2p3eA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pg6 CYTOCHROME P450 2A6

(Homo sapiens) 		PF00067
(p450) 		4 PHE A 211
ILE A 300
THR A 305
GLY A 207
 None
None
HEM  A 500 (-3.6A)
None
 0.96A 3gssB-2pg6A:
undetectable		 3gssB-2pg6A:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vo8 EXO-ALPHA-SIALIDASE

(Clostridium
perfringens) 		PF12135
(Sialidase_penC) 		4 ILE A1013
TYR A 978
THR A1048
GLY A 963
 None
 1.01A 3gssB-2vo8A:
undetectable		 3gssB-2vo8A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zb3 PROSTAGLANDIN
REDUCTASE 2

(Mus musculus) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 VAL A 183
ILE A 251
THR A 139
GLY A 172
 None
None
NDP  A 900 (-3.1A)
None
 0.91A 3gssB-2zb3A:
undetectable		 3gssB-2zb3A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zb4 PROSTAGLANDIN
REDUCTASE 2

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		4 VAL A 183
ILE A 251
THR A 139
GLY A 172
 None
None
NAP  A 500 (-3.0A)
None
 0.95A 3gssB-2zb4A:
undetectable		 3gssB-2zb4A:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ble CITRAMALATE SYNTHASE
FROM LEPTOSPIRA
INTERROGANS

(Leptospira
interrogans) 		PF00682
(HMGL-like) 		4 PHE A 206
VAL A 227
ILE A 253
GLY A 229
 None
 0.94A 3gssB-3bleA:
undetectable		 3gssB-3bleA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bpt 3-HYDROXYISOBUTYRYL-
COA HYDROLASE

(Homo sapiens) 		PF16113
(ECH_2) 		4 TYR A 122
VAL A 178
ILE A 100
GLY A 146
 None
HIU  A 502 (-4.6A)
QUE  A 501 ( 3.8A)
HIU  A 502 (-2.7A)
 1.00A 3gssB-3bptA:
undetectable		 3gssB-3bptA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cxm URACIL-DNA
GLYCOSYLASE

(Leishmania
naiffi) 		PF03167
(UDG) 		4 TYR A 208
VAL A 221
ILE A 234
GLY A 251
 URB  A 401 ( 3.3A)
None
None
None
 0.92A 3gssB-3cxmA:
undetectable		 3gssB-3cxmA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d6b GLUTARYL-COA
DEHYDROGENASE

(Burkholderia
pseudomallei) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 TYR A 373
VAL A 369
ILE A 210
GLY A 215
 None
 0.78A 3gssB-3d6bA:
1.4		 3gssB-3d6bA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e0j DNA POLYMERASE
SUBUNIT DELTA-2

(Homo sapiens) 		PF04042
(DNA_pol_E_B) 		4 VAL A 328
ILE A 336
TYR A  32
THR A  31
 None
 0.91A 3gssB-3e0jA:
undetectable		 3gssB-3e0jA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ebl GIBBERELLIN RECEPTOR
GID1

(Oryza sativa) 		PF07859
(Abhydrolase_3) 		4 TYR A  31
ILE A 133
TYR A 134
GLY A 121
 MPD  A 501 ( 4.9A)
None
GA4  A 401 (-4.8A)
GA4  A 401 ( 4.6A)
 0.94A 3gssB-3eblA:
undetectable		 3gssB-3eblA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ftb HISTIDINOL-PHOSPHATE
AMINOTRANSFERASE

(Clostridium
acetobutylicum) 		PF00155
(Aminotran_1_2) 		4 PHE A 186
ILE A  91
TYR A 111
GLY A 151
 None
 0.82A 3gssB-3ftbA:
undetectable		 3gssB-3ftbA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h2t BASEPLATE STRUCTURAL
PROTEIN GP6

(Escherichia
virus T4) 		no annotation 4 PHE A 517
VAL A 538
ILE A 592
GLY A 556
 None
 0.86A 3gssB-3h2tA:
undetectable		 3gssB-3h2tA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igx TRANSALDOLASE

(Francisella
tularensis) 		PF00923
(TAL_FSA) 		4 TYR A 217
PHE A 222
ILE A 143
GLY A 174
 None
 0.66A 3gssB-3igxA:
undetectable		 3gssB-3igxA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3is6 PUTATIVE PERMEASE
PROTEIN, ABC
TRANSPORTER

(Porphyromonas
gingivalis) 		PF12704
(MacB_PCD) 		4 TYR A 262
VAL A  84
ILE A 216
GLY A  82
 None
 0.94A 3gssB-3is6A:
undetectable		 3gssB-3is6A:
24.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kc2 UNCHARACTERIZED
PROTEIN YKR070W

(Saccharomyces
cerevisiae) 		PF13242
(Hydrolase_like)
PF13344
(Hydrolase_6) 		4 TYR A 111
VAL A 107
ILE A  79
GLY A  56
 None
 0.83A 3gssB-3kc2A:
undetectable		 3gssB-3kc2A:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lmk METABOTROPIC
GLUTAMATE RECEPTOR 5

(Homo sapiens) 		PF01094
(ANF_receptor) 		4 PHE A 337
VAL A 334
ILE A 404
GLY A 398
 None
 1.00A 3gssB-3lmkA:
undetectable		 3gssB-3lmkA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m16 TRANSALDOLASE

(Oleispira
antarctica) 		PF00923
(TAL_FSA) 		4 TYR A 220
PHE A 225
ILE A 147
GLY A 178
 None
 0.74A 3gssB-3m16A:
undetectable		 3gssB-3m16A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mjo RIBONUCLEOTIDE
REDUCTASE SUBUNIT
R2F

(Corynebacterium
ammoniagenes) 		PF00268
(Ribonuc_red_sm) 		4 TYR A 115
PHE A  70
ILE A 199
GLY A 175
 None
 0.90A 3gssB-3mjoA:
undetectable		 3gssB-3mjoA:
18.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus musculus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 PHE A   8
VAL A  10
TYR A 108
THR A 105
GLY A 205
 GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.1A)
None
GTB  A 210 (-3.7A)
 1.06A 3gssB-3o76A:
36.6		 3gssB-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus musculus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		6 TYR A   7
PHE A   8
VAL A  10
TYR A 108
THR A 109
GLY A 205
 None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.1A)
None
GTB  A 210 (-3.7A)
 0.35A 3gssB-3o76A:
36.6		 3gssB-3o76A:
84.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		4 ILE A 216
TYR A 250
THR A 251
GLY A 319
 None
 0.87A 3gssB-3opyA:
undetectable		 3gssB-3opyA:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3otr ENOLASE

(Toxoplasma
gondii) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 VAL A  23
ILE A  89
THR A 363
GLY A 118
 None
 0.98A 3gssB-3otrA:
undetectable		 3gssB-3otrA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvz UDP-N-ACETYLGLUCOSAM
INE 4,6-DEHYDRATASE

(Aliivibrio
fischeri) 		PF02719
(Polysacc_synt_2) 		4 TYR A 157
VAL A 113
ILE A  95
TYR A 100
 None
None
NAD  A 501 (-3.9A)
None
 0.84A 3gssB-3pvzA:
undetectable		 3gssB-3pvzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rjd HIGH AFFINITY
IMMUNOGLOBULIN GAMMA
FC RECEPTOR I

(Homo sapiens) 		PF00047
(ig)
PF13895
(Ig_2)
PF13927
(Ig_3) 		4 VAL A 269
ILE A 160
THR A 184
GLY A 117
 None
None
NAG  A 369 ( 4.7A)
None
 0.90A 3gssB-3rjdA:
undetectable		 3gssB-3rjdA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t90 GLUCOSE-6-PHOSPHATE
ACETYLTRANSFERASE 1

(Arabidopsis
thaliana) 		PF00583
(Acetyltransf_1) 		4 PHE A 107
VAL A 104
ILE A  64
GLY A  68
 None
 0.81A 3gssB-3t90A:
undetectable		 3gssB-3t90A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tbj ACTIBIND

(Aspergillus
niger) 		PF00445
(Ribonuclease_T2) 		4 TYR A 237
VAL A 228
ILE A 145
GLY A 230
 None
 0.89A 3gssB-3tbjA:
undetectable		 3gssB-3tbjA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3teh PHENYLALANYL-TRNA
SYNTHETASE ALPHA
CHAIN

(Thermus
thermophilus) 		PF01409
(tRNA-synt_2d) 		4 TYR A 307
PHE A 291
VAL A 294
THR A 179
 None
 0.83A 3gssB-3tehA:
undetectable		 3gssB-3tehA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr7 URACIL-DNA
GLYCOSYLASE

(Coxiella
burnetii) 		PF03167
(UDG) 		4 TYR A  69
VAL A  82
ILE A  95
GLY A 111
 None
 0.87A 3gssB-3tr7A:
undetectable		 3gssB-3tr7A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vsm OCCLUSION-DERIVED
VIRUS ENVELOPE
PROTEIN E66

(Autographa
californica
multiple
nucleopolyhedrovirus) 		PF04850
(Baculo_E66) 		4 ILE A 271
TYR A 310
THR A 311
GLY A 241
 None
 0.98A 3gssB-3vsmA:
4.5		 3gssB-3vsmA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wdj TYPE I PULLULANASE

(Anoxybacillus
sp. LM18-11) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		4 VAL A 592
ILE A 267
TYR A 225
GLY A 569
 None
 0.88A 3gssB-3wdjA:
undetectable		 3gssB-3wdjA:
14.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zef PRE-MRNA-SPLICING
FACTOR 8

(Saccharomyces
cerevisiae) 		PF08084
(PROCT)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 TYR B1164
TYR B1345
THR B1344
GLY B1264
 None
 0.99A 3gssB-3zefB:
0.3		 3gssB-3zefB:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zoq URACIL-DNA
GLYCOSYLASE

(Bacillus
subtilis) 		PF03167
(UDG) 		4 TYR A  67
VAL A  80
ILE A  93
GLY A 109
 None
 0.94A 3gssB-3zoqA:
undetectable		 3gssB-3zoqA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a3r ENOLASE

(Bacillus
subtilis) 		PF00113
(Enolase_C)
PF03952
(Enolase_N) 		4 VAL A  23
ILE A  90
THR A 347
GLY A 113
 None
 0.98A 3gssB-4a3rA:
undetectable		 3gssB-4a3rA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aec CYSTEINE SYNTHASE,
MITOCHONDRIAL

(Arabidopsis
thaliana) 		PF00291
(PALP) 		4 VAL A 310
ILE A 273
THR A 268
GLY A 298
 None
 0.95A 3gssB-4aecA:
undetectable		 3gssB-4aecA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b0i 3-HYDROXYDECANOYL-[A
CYL-CARRIER-PROTEIN]
DEHYDRATASE

(Pseudomonas
aeruginosa) 		PF07977
(FabA) 		4 ILE A 154
TYR A 155
THR A 146
GLY A  79
 None
 0.89A 3gssB-4b0iA:
undetectable		 3gssB-4b0iA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg2 PATF

(Prochloron
didemni) 		no annotation 4 PHE A  27
VAL A  29
TYR A  67
GLY A  65
 None
 0.73A 3gssB-4bg2A:
undetectable		 3gssB-4bg2A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bq4 B-AGARASE

(Saccharophagus
degradans) 		PF02449
(Glyco_hydro_42) 		4 ILE A 785
TYR A 786
THR A 787
GLY A 292
 None
 0.97A 3gssB-4bq4A:
undetectable		 3gssB-4bq4A:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4chl PERSULFIDE
DIOXYGENASE ETHE1,
MITOCHONDRIAL

(Homo sapiens) 		PF00753
(Lactamase_B) 		4 TYR A  38
PHE A 151
ILE A 158
GLY A 153
 None
 1.00A 3gssB-4chlA:
undetectable		 3gssB-4chlA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvc ALCOHOL
DEHYDROGENASE

(Pseudogluconobacter
saccharoketogenes) 		PF13360
(PQQ_2) 		4 VAL A 399
ILE A 497
THR A 373
GLY A 380
 None
 0.94A 3gssB-4cvcA:
undetectable		 3gssB-4cvcA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e6y CITRATE SYNTHASE

(Vibrio
vulnificus) 		PF00285
(Citrate_synt) 		4 ILE A  66
TYR A  59
THR A  58
GLY A  26
 None
 0.95A 3gssB-4e6yA:
undetectable		 3gssB-4e6yA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hst GLUTARYL-7-AMINOCEPH
ALOSPORANIC ACID
ACYLASE BETA CHAIN

(Pseudomonas) 		PF01804
(Penicil_amidase) 		4 TYR B  32
PHE B  31
VAL B  49
ILE B 176
 GLJ  B 601 (-4.9A)
None
None
None
 0.87A 3gssB-4hstB:
undetectable		 3gssB-4hstB:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyl URACIL-DNA
GLYCOSYLASE

(Gadus morhua) 		PF03167
(UDG) 		4 TYR A 147
VAL A 160
ILE A 173
GLY A 190
 None
 0.93A 3gssB-4lylA:
undetectable		 3gssB-4lylA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyl URACIL-DNA
GLYCOSYLASE

(Gadus morhua) 		PF03167
(UDG) 		4 VAL A 160
ILE A 173
TYR A 174
GLY A 190
 None
 0.98A 3gssB-4lylA:
undetectable		 3gssB-4lylA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mca GLYCEROL
DEHYDROGENASE

(Serratia
plymuthica) 		PF00465
(Fe-ADH) 		4 TYR A 131
PHE A 137
THR A 279
GLY A 259
 None
 0.93A 3gssB-4mcaA:
undetectable		 3gssB-4mcaA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pue ENDO-1,4-BETA-XYLANA
SE

(Geobacillus
stearothermophilus) 		PF00331
(Glyco_hydro_10) 		4 PHE A 360
ILE A 284
TYR A 281
GLY A 363
 None
 0.64A 3gssB-4pueA:
undetectable		 3gssB-4pueA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlj BETA-GLUCOSIDASE 7

(Oryza sativa) 		PF00232
(Glyco_hydro_1) 		4 VAL A  24
TYR A 315
THR A 316
GLY A 386
 None
CTT  A1001 (-4.2A)
None
None
 1.00A 3gssB-4qljA:
undetectable		 3gssB-4qljA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qxw CARCINOEMBRYONIC
ANTIGEN-RELATED CELL
ADHESION MOLECULE 1

(Homo sapiens) 		PF07686
(V-set) 		4 VAL A  78
ILE A  45
TYR A  86
THR A  87
 None
 0.98A 3gssB-4qxwA:
undetectable		 3gssB-4qxwA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r0k DIPEPTIDYL-PEPTIDASE
VI

(Bacteroides
thetaiotaomicron) 		PF00877
(NLPC_P60) 		4 VAL A 228
ILE A 216
THR A 319
GLY A 315
 None
None
None
GOL  A 403 ( 4.3A)
 0.70A 3gssB-4r0kA:
undetectable		 3gssB-4r0kA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tr6 DNA POLYMERASE III
SUBUNIT BETA

(Bacillus
subtilis) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 VAL A  23
ILE A  31
TYR A 125
GLY A  48
 None
 0.93A 3gssB-4tr6A:
undetectable		 3gssB-4tr6A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tv7 HTH-TYPE
TRANSCRIPTIONAL
REGULATORY PROTEIN
GABR

(Bacillus
subtilis) 		PF00155
(Aminotran_1_2)
PF00392
(GntR) 		4 TYR A 281
ILE A 446
THR A 403
GLY A 253
 LLP  A 312 ( 4.0A)
None
None
None
 0.81A 3gssB-4tv7A:
undetectable		 3gssB-4tv7A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tvm CITRATE SYNTHASE

(Mycobacterium
tuberculosis) 		PF00285
(Citrate_synt) 		4 ILE A  68
TYR A  61
THR A  60
GLY A  27
 None
 0.98A 3gssB-4tvmA:
undetectable		 3gssB-4tvmA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wy8 ESTERASE

(Rhizomucor
miehei) 		PF07859
(Abhydrolase_3) 		4 ILE A 191
TYR A 192
THR A 257
GLY A 292
 None
 0.93A 3gssB-4wy8A:
undetectable		 3gssB-4wy8A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9t UNCHARACTERIZED
PROTEIN UPF0065

(Polaromonas sp.
JS666) 		PF03401
(TctC) 		4 VAL A 252
TYR A  28
THR A  27
GLY A  88
 None
 0.93A 3gssB-4x9tA:
undetectable		 3gssB-4x9tA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xib E3 UBIQUITIN-PROTEIN
LIGASE MIB1

(Homo sapiens) 		PF00569
(ZZ)
PF06701
(MIB_HERC2) 		4 VAL A  36
ILE A 181
THR A 179
GLY A 150
 None
 1.01A 3gssB-4xibA:
undetectable		 3gssB-4xibA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5amq RNA POLYMERASE L

(California
encephalitis
orthobunyavirus) 		PF04196
(Bunya_RdRp)
PF15518
(L_protein_N) 		4 TYR A1098
PHE A 943
THR A 836
GLY A 963
 None
 0.91A 3gssB-5amqA:
undetectable		 3gssB-5amqA:
7.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5brq GLYCOSIDE HYDROLASE
FAMILY 13

(Bacillus
licheniformis) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		4 VAL A 421
ILE A  43
TYR A  15
GLY A 367
 None
 0.99A 3gssB-5brqA:
undetectable		 3gssB-5brqA:
17.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d73 GLUTATHIONE
S-TRANSFERASE

(Wuchereria
bancrofti) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
PHE A   8
TYR A 106
GLY A 204
 None
GSH  A 301 (-4.9A)
None
None
 0.42A 3gssB-5d73A:
30.9		 3gssB-5d73A:
42.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5d73 GLUTATHIONE
S-TRANSFERASE

(Wuchereria
bancrofti) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A 106
TYR A   7
THR A   6
GLY A  12
 None
 0.74A 3gssB-5d73A:
30.9		 3gssB-5d73A:
42.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dis GTP-BINDING NUCLEAR
PROTEIN RAN

(Homo sapiens) 		PF00071
(Ras) 		4 TYR B 155
VAL B 124
TYR B 146
GLY B 121
 None
 0.94A 3gssB-5disB:
undetectable		 3gssB-5disB:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ewo STRUCTURAL PROTEIN

(Mamastrovirus 1) 		PF12226
(Astro_capsid_p) 		4 TYR A 588
PHE A 582
VAL A 543
GLY A 546
 None
 0.93A 3gssB-5ewoA:
undetectable		 3gssB-5ewoA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5frs SISTER CHROMATID
COHESION PROTEIN
PDS5

(Saccharomyces
cerevisiae) 		PF12717
(Cnd1) 		4 TYR A 157
VAL A 219
ILE A 179
GLY A 172
 None
 0.86A 3gssB-5frsA:
undetectable		 3gssB-5frsA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gnd PUTATIVE SERINE
PROTEASE HHOA

(Synechocystis
sp. PCC 6803) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 PHE A 115
VAL A  69
ILE A 189
GLY A 192
 None
 0.97A 3gssB-5gndA:
undetectable		 3gssB-5gndA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jk7 URACIL-DNA
GLYCOSYLASE

(Homo sapiens) 		PF03167
(UDG) 		4 TYR D 147
VAL D 160
ILE D 173
GLY D 190
 None
 0.98A 3gssB-5jk7D:
undetectable		 3gssB-5jk7D:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v41 POLYKETIDE SYNTHASE
PKS13 (TERMINATION
POLYKETIDE SYNTHASE)

(Mycobacterium
tuberculosis) 		PF00975
(Thioesterase) 		4 TYR A1637
VAL A1611
ILE A1575
GLY A1609
 J24  A1801 (-4.3A)
None
None
None
 0.99A 3gssB-5v41A:
undetectable		 3gssB-5v41A:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ve3 BPPRF

(Paraburkholderia
phytofirmans) 		no annotation 4 TYR B  17
PHE B 130
ILE B 137
GLY B 132
 None
 1.00A 3gssB-5ve3B:
undetectable		 3gssB-5ve3B:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x55 PROBABLE URACIL-DNA
GLYCOSYLASE

(Acanthamoeba
polyphaga
mimivirus) 		PF03167
(UDG) 		4 TYR A 193
VAL A 211
ILE A 224
GLY A 241
 None
 0.80A 3gssB-5x55A:
undetectable		 3gssB-5x55A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xwb 3-PHOSPHOSHIKIMATE
1-CARBOXYVINYLTRANSF
ERASE

(Colwellia
psychrerythraea) 		PF00275
(EPSP_synthase) 		4 PHE A 250
VAL A 261
ILE A   9
GLY A 254
 None
 0.94A 3gssB-5xwbA:
undetectable		 3gssB-5xwbA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y0q UPF0348 PROTEIN
B4417_3650

(Bacillus
subtilis) 		no annotation 4 TYR A  72
PHE A  41
VAL A  76
GLY A  45
 None
 0.89A 3gssB-5y0qA:
undetectable		 3gssB-5y0qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y1a -

(-) 		no annotation 4 PHE A 144
VAL A 126
ILE A 242
GLY A 246
 None
 0.97A 3gssB-5y1aA:
undetectable		 3gssB-5y1aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y50 PROTEIN
DETOXIFICATION 14

(Arabidopsis
thaliana) 		no annotation 4 VAL A 348
ILE A 302
THR A 337
GLY A 345
 None
 0.90A 3gssB-5y50A:
2.4		 3gssB-5y50A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6coy CHLORIDE CHANNEL
PROTEIN 1

(Homo sapiens) 		no annotation 4 VAL A 544
ILE A 290
THR A 268
GLY A 284
 None
 0.79A 3gssB-6coyA:
undetectable		 3gssB-6coyA:
15.38