SIMILAR PATTERNS OF AMINO ACIDS FOR 3GP0_A_NILA1_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a2o CHEB METHYLESTERASE

(Salmonella
enterica) 		PF00072
(Response_reg)
PF01339
(CheB_methylest) 		4 ARG A 134
VAL A 278
LEU A 292
ILE A 302
 None
 0.80A 3gp0A-1a2oA:
undetectable		 3gp0A-1a2oA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b25 PROTEIN
(FORMALDEHYDE
FERREDOXIN
OXIDOREDUCTASE)

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 ARG A 146
VAL A 174
LEU A 342
ILE A 161
 None
 0.95A 3gp0A-1b25A:
undetectable		 3gp0A-1b25A:
20.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1cm8 PHOSPHORYLATED MAP
KINASE P38-GAMMA

(Homo sapiens) 		PF00069
(Pkinase) 		5 ARG A  70
VAL A  86
LEU A 107
MET A 112
ILE A 169
 None
 0.75A 3gp0A-1cm8A:
37.8		 3gp0A-1cm8A:
63.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d7w MYELOPEROXIDASE

(Homo sapiens) 		PF03098
(An_peroxidase) 		4 VAL C 372
LEU C 254
LEU C 246
ILE C 230
 None
 0.96A 3gp0A-1d7wC:
undetectable		 3gp0A-1d7wC:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1do5 HUMAN COPPER
CHAPERONE FOR
SUPEROXIDE DISMUTASE
DOMAIN II

(Homo sapiens) 		PF00080
(Sod_Cu) 		4 VAL A 102
LEU A 106
LEU A 168
ILE A  92
 None
 0.95A 3gp0A-1do5A:
undetectable		 3gp0A-1do5A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gwc GLUTATHIONE
S-TRANSFERASE TSI-1

(Aegilops
tauschii) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LYS A  28
LEU A  30
LEU A  23
ILE A  71
 None
 0.97A 3gp0A-1gwcA:
undetectable		 3gp0A-1gwcA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1l2q MONOMETHYLAMINE
METHYLTRANSFERASE

(Methanosarcina
barkeri) 		PF05369
(MtmB) 		4 LYS A  85
VAL A 277
LEU A 287
ILE A 276
 None
 0.96A 3gp0A-1l2qA:
undetectable		 3gp0A-1l2qA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus) 		PF07714
(Pkinase_Tyr) 		4 LYS A 608
LEU A 652
MET A 657
ILE A 740
 None
 0.94A 3gp0A-1lufA:
23.1		 3gp0A-1lufA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rx0 ACYL-COA
DEHYDROGENASE FAMILY
MEMBER 8,
MITOCHONDRIAL

(Homo sapiens) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		4 LYS A 132
VAL A 181
MET A 110
ILE A 196
 None
 0.90A 3gp0A-1rx0A:
undetectable		 3gp0A-1rx0A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9a CHLOROCATECHOL
1,2-DIOXYGENASE

(Rhodococcus
opacus) 		PF00775
(Dioxygenase_C)
PF04444
(Dioxygenase_N) 		4 ARG A 165
VAL A 151
LEU A 147
ILE A 123
 None
 0.95A 3gp0A-1s9aA:
undetectable		 3gp0A-1s9aA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t3q QUINOLINE
2-OXIDOREDUCTASE
LARGE SUBUNIT

(Pseudomonas
putida) 		PF01315
(Ald_Xan_dh_C)
PF02738
(Ald_Xan_dh_C2) 		4 LEU B 270
LEU B  43
MET B  42
ILE B 218
 None
 0.81A 3gp0A-1t3qB:
undetectable		 3gp0A-1t3qB:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tjn SIROHYDROCHLORIN
COBALTOCHELATASE

(Archaeoglobus
fulgidus) 		PF01903
(CbiX) 		4 ARG A   2
VAL A  65
LEU A  82
ILE A   7
 None
 0.88A 3gp0A-1tjnA:
undetectable		 3gp0A-1tjnA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tt4 PUTATIVE CYTOPLASMIC
PROTEIN

(Salmonella
enterica) 		PF04107
(GCS2) 		4 ARG A 313
VAL A 238
LEU A 164
ILE A 227
 None
 0.99A 3gp0A-1tt4A:
undetectable		 3gp0A-1tt4A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vcw PROTEASE DEGS

(Escherichia
coli) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 VAL A 154
LEU A 212
MET A 213
ILE A 172
 None
 0.87A 3gp0A-1vcwA:
undetectable		 3gp0A-1vcwA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ygp YEAST GLYCOGEN
PHOSPHORYLASE

(Saccharomyces
cerevisiae) 		PF00343
(Phosphorylase) 		4 VAL A 347
LEU A 214
LEU A 359
ILE A 346
 None
 0.94A 3gp0A-1ygpA:
undetectable		 3gp0A-1ygpA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yp4 GLUCOSE-1-PHOSPHATE
ADENYLYLTRANSFERASE
SMALL SUBUNIT

(Solanum
tuberosum) 		PF00483
(NTP_transferase) 		4 ARG A  33
VAL A  72
LEU A 128
ILE A  25
 None
 0.96A 3gp0A-1yp4A:
undetectable		 3gp0A-1yp4A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yqe HYPOTHETICAL UPF0204
PROTEIN AF0625

(Archaeoglobus
fulgidus) 		PF04414
(tRNA_deacylase) 		4 VAL A   5
LEU A 174
MET A 173
ILE A  70
 None
 1.00A 3gp0A-1yqeA:
undetectable		 3gp0A-1yqeA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z48 PROBABLE
NADH-DEPENDENT
FLAVIN
OXIDOREDUCTASE YQJM

(Bacillus
subtilis) 		PF00724
(Oxidored_FMN) 		4 ARG A 182
VAL A 214
LEU A 226
ILE A 163
 None
 0.94A 3gp0A-1z48A:
undetectable		 3gp0A-1z48A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z7c CHORIONIC
SOMATOMAMMOTROPIN
HORMONE

(Homo sapiens) 		PF00103
(Hormone_1) 		5 ARG A  91
VAL A 173
LEU A  23
LEU A  15
MET A  14
 None
 1.44A 3gp0A-1z7cA:
undetectable		 3gp0A-1z7cA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zws DAP-KINASE RELATED
PROTEIN 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  42
VAL A  76
LEU A  91
LEU A  95
 None
 0.81A 3gp0A-1zwsA:
22.6		 3gp0A-1zwsA:
28.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ac5 MAP
KINASE-INTERACTING
SERINE/THREONINE
KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A 113
VAL A 142
MET A 162
ILE A 224
 None
 0.88A 3gp0A-2ac5A:
20.5		 3gp0A-2ac5A:
28.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ac5 MAP
KINASE-INTERACTING
SERINE/THREONINE
KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A 142
LEU A 157
MET A 162
ILE A 224
 None
 0.73A 3gp0A-2ac5A:
20.5		 3gp0A-2ac5A:
28.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2b1p MITOGEN-ACTIVATED
PROTEIN KINASE 10

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 144
LEU A 148
MET A 149
ILE A 205
 AIZ  A 501 (-4.2A)
AIZ  A 501 ( 4.7A)
None
None
 0.76A 3gp0A-2b1pA:
35.7		 3gp0A-2b1pA:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2b1p MITOGEN-ACTIVATED
PROTEIN KINASE 10

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  93
LEU A 144
LEU A 148
ILE A 205
 AIZ  A 501 (-3.8A)
AIZ  A 501 (-4.2A)
AIZ  A 501 ( 4.7A)
None
 0.94A 3gp0A-2b1pA:
35.7		 3gp0A-2b1pA:
48.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b3b GLUCOSE-BINDING
PROTEIN

(Thermus
thermophilus) 		PF01547
(SBP_bac_1) 		4 ARG A 210
VAL A 363
LEU A 172
ILE A 366
 None
 0.97A 3gp0A-2b3bA:
undetectable		 3gp0A-2b3bA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bi0 HYPOTHETICAL PROTEIN
RV0216

(Mycobacterium
tuberculosis) 		no annotation 4 ARG A 152
VAL A  44
LEU A 328
ILE A  43
 None
 0.86A 3gp0A-2bi0A:
undetectable		 3gp0A-2bi0A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2br4 CEPHALOSPORIN
HYDROXYLASE CMCI

(Streptomyces
clavuligerus) 		PF04989
(CmcI) 		4 ARG A  81
VAL A 228
MET A 169
ILE A 184
 None
 0.94A 3gp0A-2br4A:
undetectable		 3gp0A-2br4A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bru NAD(P)
TRANSHYDROGENASE
SUBUNIT ALPHA

(Escherichia
coli) 		PF01262
(AlaDh_PNT_C)
PF05222
(AlaDh_PNT_N) 		4 ARG A1009
VAL A1360
LEU A1331
ILE A1361
 None
 0.91A 3gp0A-2bruA:
undetectable		 3gp0A-2bruA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dc0 PROBABLE AMIDASE

(Thermus
thermophilus) 		PF01425
(Amidase) 		4 ARG A   8
VAL A 182
LEU A 161
LEU A 164
 None
 0.92A 3gp0A-2dc0A:
undetectable		 3gp0A-2dc0A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ejv L-THREONINE
3-DEHYDROGENASE

(Thermus
thermophilus) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 VAL A 194
LEU A 216
LEU A 221
ILE A 170
 None
 0.89A 3gp0A-2ejvA:
undetectable		 3gp0A-2ejvA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2eyq TRANSCRIPTION-REPAIR
COUPLING FACTOR

(Escherichia
coli) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF02559
(CarD_CdnL_TRCF)
PF03461
(TRCF) 		4 VAL A 637
LEU A 773
MET A 616
ILE A 609
 None
 0.98A 3gp0A-2eyqA:
undetectable		 3gp0A-2eyqA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gq3 MALATE SYNTHASE G

(Mycobacterium
tuberculosis) 		PF01274
(Malate_synthase) 		4 VAL A 118
LEU A 122
LEU A 128
ILE A 269
 COA  A 800 (-3.9A)
EPE  A5000 (-4.1A)
None
None
 0.71A 3gp0A-2gq3A:
undetectable		 3gp0A-2gq3A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2him L-ASPARAGINASE 1

(Escherichia
coli) 		PF00710
(Asparaginase) 		4 LYS A   3
ARG A  43
VAL A   8
ILE A  51
 None
 0.95A 3gp0A-2himA:
undetectable		 3gp0A-2himA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hw6 MAP
KINASE-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  78
ARG A  90
LEU A 122
ILE A 189
 None
 0.81A 3gp0A-2hw6A:
20.6		 3gp0A-2hw6A:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jc6 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1D

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  52
LEU A  96
LEU A 100
ILE A  81
 None
None
QPP  A1314 (-4.5A)
None
 0.91A 3gp0A-2jc6A:
20.2		 3gp0A-2jc6A:
28.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jc6 CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE 1D

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  52
LEU A  96
LEU A 100
ILE A 163
 None
None
QPP  A1314 (-4.5A)
None
 0.60A 3gp0A-2jc6A:
20.2		 3gp0A-2jc6A:
28.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o0h DNA PACKAGING
PROTEIN GP17

(Escherichia
virus T4) 		PF03237
(Terminase_6) 		4 VAL A 157
LEU A 164
LEU A 147
ILE A 284
 None
 0.91A 3gp0A-2o0hA:
undetectable		 3gp0A-2o0hA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oxc PROBABLE
ATP-DEPENDENT RNA
HELICASE DDX20

(Homo sapiens) 		PF00270
(DEAD) 		4 ARG A 140
LEU A 240
MET A 239
ILE A 229
 None
 0.99A 3gp0A-2oxcA:
undetectable		 3gp0A-2oxcA:
22.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2phk PHOSPHORYLASE KINASE

(Oryctolagus
cuniculus) 		PF00069
(Pkinase) 		5 LYS A  48
LEU A 101
LEU A 105
MET A 106
ILE A  86
 ATP  A 381 (-3.2A)
None
None
None
None
 1.45A 3gp0A-2phkA:
22.8		 3gp0A-2phkA:
30.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pyb NEUTROPHIL
ACTIVATING PROTEIN

(Borreliella
burgdorferi) 		PF00210
(Ferritin) 		5 ARG A  72
LEU A  24
LEU A 146
MET A 143
ILE A 127
 None
 1.38A 3gp0A-2pybA:
undetectable		 3gp0A-2pybA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q1y CELL DIVISION
PROTEIN FTSZ

(Mycobacterium
tuberculosis) 		PF00091
(Tubulin)
PF12327
(FtsZ_C) 		4 ARG A  60
VAL A  14
MET A  27
ILE A  38
 None
 0.90A 3gp0A-2q1yA:
undetectable		 3gp0A-2q1yA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r3u PROTEASE DEGS

(Escherichia
coli) 		PF13365
(Trypsin_2) 		4 VAL A 154
LEU A 212
MET A 213
ILE A 172
 None
 0.86A 3gp0A-2r3uA:
undetectable		 3gp0A-2r3uA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4b RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LEU A 794
LEU A 798
MET A 799
ILE A 859
 GW7  A   1 (-4.1A)
GW7  A   1 (-4.5A)
None
None
 0.55A 3gp0A-2r4bA:
20.6		 3gp0A-2r4bA:
26.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4b RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-4

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LYS A 751
LEU A 794
LEU A 798
ILE A 859
 GW7  A   1 (-3.9A)
GW7  A   1 (-4.1A)
GW7  A   1 (-4.5A)
None
 0.80A 3gp0A-2r4bA:
20.6		 3gp0A-2r4bA:
26.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vws YFAU, 2-KETO-3-DEOXY
SUGAR ALDOLASE

(Escherichia
coli) 		PF03328
(HpcH_HpaI) 		4 VAL A 150
LEU A 180
LEU A 216
ILE A  96
 None
 0.97A 3gp0A-2vwsA:
undetectable		 3gp0A-2vwsA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w1t STAGE V SPORULATION
PROTEIN T

(Bacillus
subtilis) 		PF04014
(MazE_antitoxin)
PF15714
(SpoVT_C) 		4 ARG B 174
VAL B  74
LEU B  55
ILE B 150
 None
 0.99A 3gp0A-2w1tB:
undetectable		 3gp0A-2w1tB:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w4k DEATH-ASSOCIATED
PROTEIN KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		5 LYS A  42
VAL A  76
LEU A  91
LEU A  95
ILE A 159
 ADP  A1303 (-2.7A)
None
None
None
None
 0.80A 3gp0A-2w4kA:
22.5		 3gp0A-2w4kA:
29.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y7j PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM

(Homo sapiens) 		PF00069
(Pkinase) 		5 LYS A  53
LEU A 105
LEU A 109
MET A 110
ILE A  90
 None
None
B49  A1294 ( 4.7A)
None
None
 1.46A 3gp0A-2y7jA:
24.2		 3gp0A-2y7jA:
24.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z8c INSULIN RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 VAL A1059
LEU A1078
MET A1079
ILE A1148
 None
S91  A   1 (-4.7A)
None
None
 0.69A 3gp0A-2z8cA:
22.3		 3gp0A-2z8cA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zwa LEUCINE CARBOXYL
METHYLTRANSFERASE 2

(Saccharomyces
cerevisiae) 		PF04072
(LCM)
PF13418
(Kelch_4) 		4 ARG A  95
VAL A  41
LEU A 121
LEU A  64
 None
 0.96A 3gp0A-2zwaA:
2.2		 3gp0A-2zwaA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahr ERO1-LIKE PROTEIN
ALPHA

(Homo sapiens) 		PF04137
(ERO1) 		4 ARG A  64
VAL A 441
LEU A 408
ILE A 440
 None
 0.92A 3gp0A-3ahrA:
undetectable		 3gp0A-3ahrA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bpq TOXIN RELE3

(Methanocaldococcus
jannaschii) 		PF05016
(ParE_toxin) 		4 ARG B  23
VAL B   3
LEU B  13
ILE B  72
 None
 0.83A 3gp0A-3bpqB:
undetectable		 3gp0A-3bpqB:
14.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3coi MITOGEN-ACTIVATED
PROTEIN KINASE 13

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  54
VAL A  84
LEU A 105
ILE A 166
 None
 0.60A 3gp0A-3coiA:
36.5		 3gp0A-3coiA:
60.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3coi MITOGEN-ACTIVATED
PROTEIN KINASE 13

(Homo sapiens) 		PF00069
(Pkinase) 		4 VAL A  84
LEU A 105
MET A 110
ILE A 166
 None
 0.60A 3gp0A-3coiA:
36.5		 3gp0A-3coiA:
60.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dak SERINE/THREONINE-PRO
TEIN KINASE OSR1

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  46
LEU A  90
LEU A  94
ILE A 162
 ANP  A   1 (-2.8A)
None
None
None
 0.91A 3gp0A-3dakA:
19.8		 3gp0A-3dakA:
29.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7o MITOGEN-ACTIVATED
PROTEIN KINASE 9

(Homo sapiens) 		PF00069
(Pkinase) 		4 LEU A 106
LEU A 110
MET A 111
ILE A 167
 None
35F  A   1 (-4.5A)
None
None
 0.53A 3gp0A-3e7oA:
35.6		 3gp0A-3e7oA:
49.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e98 GAF DOMAIN OF
UNKNOWN FUNCTION

(Pseudomonas
aeruginosa) 		PF04340
(DUF484) 		4 ARG A 220
VAL A 119
LEU A 123
ILE A 194
 None
 0.97A 3gp0A-3e98A:
undetectable		 3gp0A-3e98A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eh7 4-HYDROXYBUTYRATE
COA-TRANSFERASE

(Porphyromonas
gingivalis) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		4 VAL A 323
LEU A 318
MET A 355
ILE A 314
 None
 0.93A 3gp0A-3eh7A:
undetectable		 3gp0A-3eh7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hko CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE WITH A KINASE
DOMAIN AND 2
CALMODULIN-LIKE EF
HANDS

(Cryptosporidium
parvum) 		PF00069
(Pkinase) 		4 LYS A  39
LEU A  87
LEU A  91
ILE A  72
 ANP  A 329 (-2.7A)
None
ANP  A 329 ( 4.7A)
None
 0.85A 3gp0A-3hkoA:
22.4		 3gp0A-3hkoA:
29.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iby FERROUS IRON
TRANSPORT PROTEIN B

(Legionella
pneumophila) 		PF02421
(FeoB_N) 		4 ARG A  98
VAL A 113
LEU A 117
ILE A  87
 None
 0.84A 3gp0A-3ibyA:
undetectable		 3gp0A-3ibyA:
24.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kl8 CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE II

(Caenorhabditis
elegans) 		PF00069
(Pkinase) 		4 LYS A  42
LEU A  87
LEU A  91
ILE A  72
 None
 0.85A 3gp0A-3kl8A:
23.0		 3gp0A-3kl8A:
30.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kmu INTEGRIN-LINKED
KINASE

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		5 LYS A 220
VAL A 250
LEU A 267
MET A 272
ILE A 335
 None
 1.06A 3gp0A-3kmuA:
19.6		 3gp0A-3kmuA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kn5 RIBOSOMAL PROTEIN S6
KINASE ALPHA-5

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A 455
LEU A 496
LEU A 500
ILE A 481
 None
None
ANP  A 400 (-4.6A)
None
 0.97A 3gp0A-3kn5A:
18.1		 3gp0A-3kn5A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kn5 RIBOSOMAL PROTEIN S6
KINASE ALPHA-5

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A 455
LEU A 496
LEU A 500
ILE A 563
 None
None
ANP  A 400 (-4.6A)
None
 0.91A 3gp0A-3kn5A:
18.1		 3gp0A-3kn5A:
28.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgi PROTEASE DEGS

(Escherichia
coli) 		PF13365
(Trypsin_2) 		4 LEU A 117
LEU A 248
MET A 245
ILE A  84
 None
 0.93A 3gp0A-3lgiA:
undetectable		 3gp0A-3lgiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgi PROTEASE DEGS

(Escherichia
coli) 		PF13365
(Trypsin_2) 		4 VAL A 154
LEU A 212
MET A 213
ILE A 172
 None
 0.87A 3gp0A-3lgiA:
undetectable		 3gp0A-3lgiA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lm5 SERINE/THREONINE-PRO
TEIN KINASE 17B

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  62
VAL A  93
LEU A 108
ILE A 177
 QUE  A   1 (-4.1A)
None
None
None
 0.49A 3gp0A-3lm5A:
24.0		 3gp0A-3lm5A:
27.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lw0 INSULIN-LIKE GROWTH
FACTOR 1 RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 LYS A1033
VAL A1062
LEU A1081
ILE A1151
 CCX  A   1 ( 3.7A)
None
None
None
 0.94A 3gp0A-3lw0A:
22.8		 3gp0A-3lw0A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lw0 INSULIN-LIKE GROWTH
FACTOR 1 RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 VAL A1062
LEU A1081
MET A1082
ILE A1151
 None
 0.68A 3gp0A-3lw0A:
22.8		 3gp0A-3lw0A:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3moi PROBABLE
DEHYDROGENASE

(Bordetella
bronchiseptica) 		PF01408
(GFO_IDH_MocA)
PF02894
(GFO_IDH_MocA_C) 		4 VAL A  93
LEU A  17
MET A  18
ILE A  70
 None
 0.99A 3gp0A-3moiA:
undetectable		 3gp0A-3moiA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ne5 CATION EFFLUX SYSTEM
PROTEIN CUSA

(Escherichia
coli) 		PF00873
(ACR_tran) 		4 VAL A 496
LEU A 364
MET A 410
ILE A 499
 None
 0.95A 3gp0A-3ne5A:
undetectable		 3gp0A-3ne5A:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvt 3-DEOXY-D-ARABINO-HE
PTULOSONATE
7-PHOSPHATE SYNTHASE

(Listeria
monocytogenes) 		PF00793
(DAHP_synth_1)
PF01817
(CM_2) 		4 LYS A 231
ARG A 157
VAL A 185
ILE A 149
 ACT  A 363 (-2.3A)
None
None
None
 0.63A 3gp0A-3nvtA:
undetectable		 3gp0A-3nvtA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nyo G PROTEIN-COUPLED
RECEPTOR KINASE 6

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		5 VAL A 246
LEU A 261
LEU A 265
MET A 266
ILE A 327
 None
None
AMP  A 577 ( 4.9A)
None
None
 0.75A 3gp0A-3nyoA:
23.6		 3gp0A-3nyoA:
22.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3oht P38A

(Salmo salar) 		PF00069
(Pkinase) 		6 LYS A  54
VAL A  84
LEU A 105
LEU A 109
MET A 110
ILE A 167
 1N1  A1000 (-4.5A)
None
1N1  A1000 (-4.2A)
1N1  A1000 (-4.7A)
None
None
 0.82A 3gp0A-3ohtA:
18.9		 3gp0A-3ohtA:
68.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pg1 MITOGEN-ACTIVATED
PROTEIN KINASE,
PUTATIVE (MAP
KINASE-LIKE PROTEIN)

(Leishmania
major) 		PF00069
(Pkinase) 		4 LEU A 110
LEU A 114
MET A 115
ILE A  90
 None
 0.97A 3gp0A-3pg1A:
34.1		 3gp0A-3pg1A:
38.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3pg1 MITOGEN-ACTIVATED
PROTEIN KINASE,
PUTATIVE (MAP
KINASE-LIKE PROTEIN)

(Leishmania
major) 		PF00069
(Pkinase) 		4 LYS A  51
LEU A 114
MET A 115
ILE A  90
 None
 0.90A 3gp0A-3pg1A:
34.1		 3gp0A-3pg1A:
38.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pn1 DNA LIGASE

(Haemophilus
influenzae) 		PF01653
(DNA_ligase_aden) 		4 VAL A 171
LEU A 117
MET A  79
ILE A 228
 None
IVH  A 319 (-4.7A)
None
None
 0.90A 3gp0A-3pn1A:
undetectable		 3gp0A-3pn1A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pp0 RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		6 LYS A 753
VAL A 782
LEU A 796
LEU A 800
MET A 801
ILE A 861
 03Q  A   1 (-4.7A)
None
03Q  A   1 (-4.3A)
03Q  A   1 (-4.6A)
None
None
 0.85A 3gp0A-3pp0A:
21.2		 3gp0A-3pp0A:
25.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rac HISTIDINE-TRNA
LIGASE

(Alicyclobacillus
acidocaldarius) 		PF13393
(tRNA-synt_His) 		4 ARG A  93
LEU A 308
LEU A 314
ILE A 151
 None
 0.89A 3gp0A-3racA:
undetectable		 3gp0A-3racA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3snh DYNAMIN-1

(Homo sapiens) 		PF00169
(PH)
PF00350
(Dynamin_N)
PF01031
(Dynamin_M)
PF02212
(GED) 		4 ARG A 237
VAL A 203
LEU A 209
ILE A 232
 None
 0.93A 3gp0A-3snhA:
undetectable		 3gp0A-3snhA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sob LOW-DENSITY
LIPOPROTEIN
RECEPTOR-RELATED
PROTEIN 6

(Homo sapiens) 		PF00058
(Ldl_recept_b)
PF14670
(FXa_inhibition) 		4 ARG B  77
LEU B  24
LEU B 232
ILE B 143
 None
 0.92A 3gp0A-3sobB:
undetectable		 3gp0A-3sobB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CMR4

(Archaeoglobus
fulgidus) 		PF03787
(RAMPs) 		4 ARG C 344
VAL C 108
LEU C  50
ILE C 315
 None
 0.92A 3gp0A-3x1lC:
undetectable		 3gp0A-3x1lC:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4aur LEOA

(Escherichia
coli) 		PF00350
(Dynamin_N) 		4 VAL A 107
LEU A 112
MET A  85
ILE A  94
 None
 0.94A 3gp0A-4aurA:
undetectable		 3gp0A-4aurA:
22.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4b99 MITOGEN-ACTIVATED
PROTEIN KINASE 7

(Homo sapiens) 		PF00069
(Pkinase) 		4 LYS A  84
LEU A 139
MET A 140
ILE A 198
 None
R4L  A1394 ( 4.9A)
None
None
 0.87A 3gp0A-4b99A:
37.6		 3gp0A-4b99A:
43.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bub UDP-N-ACETYLMURAMOYL
-L-ALANYL-D-GLUTAMAT
E--LD-LYSINE LIGASE

(Thermotoga
maritima) 		PF01225
(Mur_ligase)
PF02875
(Mur_ligase_C)
PF08245
(Mur_ligase_M) 		4 ARG A 444
VAL A 370
LEU A 392
ILE A 450
 None
 0.97A 3gp0A-4bubA:
undetectable		 3gp0A-4bubA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c0e NOT1

(Chaetomium
thermophilum) 		PF04054
(Not1) 		4 VAL A1766
LEU A1724
LEU A1711
ILE A1763
 None
 0.96A 3gp0A-4c0eA:
undetectable		 3gp0A-4c0eA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cbw ACTIN, ALPHA
SKELETAL MUSCLE,
ACTIN

(Plasmodium
berghei;
synthetic
construct) 		PF00022
(Actin) 		4 VAL A 140
LEU A 294
LEU A 154
ILE A 137
 None
 0.89A 3gp0A-4cbwA:
undetectable		 3gp0A-4cbwA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cbw ACTIN, ALPHA
SKELETAL MUSCLE,
ACTIN

(Plasmodium
berghei;
synthetic
construct) 		PF00022
(Actin) 		4 VAL A 140
LEU A 294
LEU A 300
ILE A 137
 None
 0.96A 3gp0A-4cbwA:
undetectable		 3gp0A-4cbwA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d6y BACTERIAL
REGULATORY, FIS
FAMILY PROTEIN

(Brucella
abortus) 		PF00072
(Response_reg) 		4 LYS A  71
VAL A   7
LEU A  67
ILE A   5
 None
 1.00A 3gp0A-4d6yA:
undetectable		 3gp0A-4d6yA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dkl MU-TYPE OPIOID
RECEPTOR, LYSOZYME
CHIMERA

(Escherichia
virus T4;
Mus musculus) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 VAL A  78
LEU A 335
LEU A  88
ILE A  77
 None
 0.74A 3gp0A-4dklA:
undetectable		 3gp0A-4dklA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ex4 MALATE SYNTHASE G

(Mycobacterium
leprae) 		PF01274
(Malate_synthase) 		4 VAL A 118
LEU A 122
LEU A 128
ILE A 270
 None
 0.82A 3gp0A-4ex4A:
undetectable		 3gp0A-4ex4A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f4z DNA POLYMERASE IV

(Sulfolobus
acidocaldarius;
Sulfolobus
solfataricus) 		no annotation 4 LYS B 129
LEU B 126
LEU B 109
ILE B 166
 None
 0.90A 3gp0A-4f4zB:
undetectable		 3gp0A-4f4zB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f6t MOLYBDENUM STORAGE
PROTEIN SUBUNIT BETA

(Azotobacter
vinelandii) 		PF00696
(AA_kinase) 		4 ARG B 168
VAL B 145
LEU B 131
ILE B  74
 None
 0.77A 3gp0A-4f6tB:
undetectable		 3gp0A-4f6tB:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 13

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M) 		4 VAL M 399
LEU M 298
LEU M 290
ILE M 400
 None
 0.94A 3gp0A-4heaM:
undetectable		 3gp0A-4heaM:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i34 ATP-DEPENDENT CLP
PROTEASE ATP-BINDING
SUBUNIT CLPX

(Escherichia
coli) 		PF07724
(AAA_2)
PF10431
(ClpB_D2-small) 		4 ARG A 100
VAL A 310
LEU A 110
ILE A 115
 None
 0.70A 3gp0A-4i34A:
undetectable		 3gp0A-4i34A:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i7u DIHYDRODIPICOLINATE
SYNTHASE

(Agrobacterium
sp. H13-3) 		PF00701
(DHDPS) 		4 ARG A 261
LEU A 240
LEU A 193
ILE A 204
 None
 0.87A 3gp0A-4i7uA:
undetectable		 3gp0A-4i7uA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j0w U3 SMALL NUCLEOLAR
RNA-INTERACTING
PROTEIN 2

(Homo sapiens) 		PF00400
(WD40) 		4 ARG A 219
VAL A 183
LEU A 224
ILE A 171
 None
 0.83A 3gp0A-4j0wA:
2.4		 3gp0A-4j0wA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j7h EVAA 2,3-DEHYDRATASE

(Amycolatopsis
orientalis) 		PF03559
(Hexose_dehydrat) 		5 ARG A 181
VAL A 242
LEU A 133
LEU A 228
MET A 229
 None
 1.46A 3gp0A-4j7hA:
undetectable		 3gp0A-4j7hA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jcd MAJOR CAPSID PROTEIN
VP1

(Human
polyomavirus 2) 		PF00718
(Polyoma_coat) 		4 ARG A  84
VAL A 287
LEU A 282
ILE A  99
 None
 0.96A 3gp0A-4jcdA:
undetectable		 3gp0A-4jcdA:
21.21