SIMILAR PATTERNS OF AMINO ACIDS FOR 3G5D_A_1N1A1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1k2p TYROSINE-PROTEIN
KINASE BTK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 VAL A 416
ALA A 428
VAL A 458
ILE A 472
TYR A 476
GLY A 480
LEU A 528
 None
 0.53A 3g5dA-1k2pA:
26.5		 3g5dA-1k2pA:
39.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1k9a CARBOXYL-TERMINAL
SRC KINASE

(Rattus
norvegicus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		10 VAL A 209
ALA A 220
GLU A 236
MET A 240
VAL A 249
ILE A 264
THR A 266
TYR A 268
GLY A 272
LEU A 321
 None
 0.49A 3g5dA-1k9aA:
33.3		 3g5dA-1k9aA:
30.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1opk PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1

(Mus musculus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		10 LEU A 267
VAL A 275
ALA A 288
GLU A 305
MET A 309
VAL A 318
ILE A 332
THR A 334
LEU A 389
ALA A 399
 P16  A   2 ( 4.2A)
P16  A   2 (-4.5A)
P16  A   2 (-3.4A)
P16  A   2 (-4.2A)
P16  A   2 (-3.3A)
P16  A   2 ( 4.7A)
P16  A   2 (-4.1A)
P16  A   2 (-3.7A)
P16  A   2 (-4.4A)
P16  A   2 (-3.5A)
 0.58A 3g5dA-1opkA:
32.4		 3g5dA-1opkA:
30.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1opk PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1

(Mus musculus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		10 LEU A 267
VAL A 275
ALA A 288
MET A 309
VAL A 318
ILE A 332
THR A 334
GLY A 340
LEU A 389
ALA A 399
 P16  A   2 ( 4.2A)
P16  A   2 (-4.5A)
P16  A   2 (-3.4A)
P16  A   2 (-3.3A)
P16  A   2 ( 4.7A)
P16  A   2 (-4.1A)
P16  A   2 (-3.7A)
P16  A   2 (-3.4A)
P16  A   2 (-4.4A)
P16  A   2 (-3.5A)
 0.64A 3g5dA-1opkA:
32.4		 3g5dA-1opkA:
30.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1py5 TGF-BETA RECEPTOR
TYPE I

(Homo sapiens) 		PF00069
(Pkinase)
PF08515
(TGF_beta_GS) 		7 VAL A 219
ALA A 230
GLU A 245
TYR A 282
GLY A 286
LEU A 340
ALA A 350
 PY1  A 700 ( 4.7A)
PY1  A 700 (-3.5A)
PY1  A 700 ( 4.9A)
PY1  A 700 (-4.6A)
PY1  A 700 (-3.6A)
PY1  A 700 (-4.4A)
PY1  A 700 ( 4.2A)
 0.44A 3g5dA-1py5A:
20.6		 3g5dA-1py5A:
27.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s9i DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		7 LEU A  78
VAL A  86
ALA A  99
VAL A 131
ILE A 145
GLY A 153
LEU A 201
 ATP  A 535 (-3.9A)
ATP  A 535 (-4.1A)
ATP  A 535 (-3.6A)
5EA  A1001 (-4.5A)
5EA  A1001 ( 3.7A)
ATP  A 535 ( 4.7A)
ATP  A 535 (-4.8A)
 0.55A 3g5dA-1s9iA:
7.5		 3g5dA-1s9iA:
26.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1t46 HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 595
VAL A 603
ALA A 621
GLU A 640
THR A 670
TYR A 672
GLY A 676
LEU A 799
 STI  A   3 ( 3.8A)
STI  A   3 ( 4.6A)
STI  A   3 (-3.5A)
STI  A   3 (-3.6A)
STI  A   3 (-3.2A)
STI  A   3 ( 4.0A)
STI  A   3 ( 3.8A)
STI  A   3 (-4.4A)
 0.64A 3g5dA-1t46A:
30.9		 3g5dA-1t46A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1t46 HOMO SAPIENS V-KIT
HARDY-ZUCKERMAN 4
FELINE SARCOMA VIRAL
ONCOGENE HOMOLOG

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 595
VAL A 603
ALA A 621
GLU A 640
VAL A 654
THR A 670
GLY A 676
LEU A 799
 STI  A   3 ( 3.8A)
STI  A   3 ( 4.6A)
STI  A   3 (-3.5A)
STI  A   3 (-3.6A)
STI  A   3 (-4.3A)
STI  A   3 (-3.2A)
STI  A   3 ( 3.8A)
STI  A   3 (-4.4A)
 0.71A 3g5dA-1t46A:
30.9		 3g5dA-1t46A:
35.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1u59 TYROSINE-PROTEIN
KINASE ZAP-70

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 LEU A 344
VAL A 352
ALA A 367
MET A 390
VAL A 399
GLY A 420
LEU A 468
 STU  A 100 (-3.8A)
STU  A 100 (-4.8A)
STU  A 100 (-3.2A)
None
None
STU  A 100 (-3.5A)
STU  A 100 (-4.5A)
 0.61A 3g5dA-1u59A:
31.9		 3g5dA-1u59A:
36.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zlt SERINE/THREONINE-PRO
TEIN KINASE CHK1

(Homo sapiens) 		PF00069
(Pkinase) 		7 LEU A  15
VAL A  23
ALA A  36
VAL A  68
TYR A  86
GLY A  90
LEU A 137
 HYM  A 400 (-4.2A)
HYM  A 400 (-4.3A)
HYM  A 400 (-3.5A)
HYM  A 400 (-4.8A)
HYM  A 400 (-4.7A)
None
HYM  A 400 (-4.5A)
 0.60A 3g5dA-1zltA:
16.6		 3g5dA-1zltA:
26.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2dq7 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE FYN

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		12 LEU X  17
VAL X  25
ALA X  37
GLU X  54
MET X  58
VAL X  67
ILE X  80
THR X  82
TYR X  84
GLY X  88
LEU X 137
ALA X 147
 STU  X 902 (-3.8A)
STU  X 902 ( 4.8A)
STU  X 902 (-3.1A)
STU  X 902 ( 4.4A)
None
None
None
STU  X 902 (-4.1A)
STU  X 902 (-4.6A)
STU  X 902 (-3.5A)
STU  X 902 (-4.4A)
STU  X 902 ( 4.1A)
 0.53A 3g5dA-2dq7X:
36.8		 3g5dA-2dq7X:
84.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2h8h PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC

(Homo sapiens) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		10 LEU A 273
VAL A 281
ALA A 293
VAL A 323
ILE A 336
THR A 338
TYR A 340
GLY A 344
LEU A 393
ALA A 403
 H8H  A 534 (-3.8A)
H8H  A 534 (-4.4A)
H8H  A 534 (-3.2A)
None
H8H  A 534 ( 4.5A)
H8H  A 534 (-3.1A)
H8H  A 534 (-4.3A)
H8H  A 534 (-3.3A)
H8H  A 534 (-4.5A)
H8H  A 534 ( 4.0A)
 0.49A 3g5dA-2h8hA:
34.1		 3g5dA-2h8hA:
52.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hck HEMATOPOETIC CELL
KINASE HCK

(Homo sapiens) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		8 LEU A 273
VAL A 281
ALA A 293
VAL A 323
ILE A 336
THR A 338
GLY A 344
LEU A 393
 QUE  A   1 (-3.9A)
QUE  A   1 ( 4.8A)
QUE  A   1 (-3.5A)
None
None
QUE  A   1 (-3.3A)
QUE  A   1 (-3.0A)
QUE  A   1 (-4.4A)
 0.56A 3g5dA-2hckA:
32.4		 3g5dA-2hckA:
50.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hck HEMATOPOETIC CELL
KINASE HCK

(Homo sapiens) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		8 LEU A 273
VAL A 281
ALA A 293
VAL A 323
THR A 338
GLY A 344
LEU A 393
ALA A 403
 QUE  A   1 (-3.9A)
QUE  A   1 ( 4.8A)
QUE  A   1 (-3.5A)
None
QUE  A   1 (-3.3A)
QUE  A   1 (-3.0A)
QUE  A   1 (-4.4A)
QUE  A   1 ( 4.5A)
 0.64A 3g5dA-2hckA:
32.4		 3g5dA-2hckA:
50.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hk5 TYROSINE-PROTEIN
KINASE HCK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		11 LEU A 251
VAL A 259
ALA A 271
GLU A 288
MET A 292
VAL A 301
ILE A 314
THR A 316
GLY A 322
LEU A 371
ALA A 381
 1BM  A 499 ( 3.7A)
1BM  A 499 ( 4.8A)
1BM  A 499 (-3.6A)
1BM  A 499 (-3.2A)
1BM  A 499 ( 3.8A)
None
1BM  A 499 (-3.9A)
1BM  A 499 (-3.2A)
1BM  A 499 (-3.5A)
1BM  A 499 (-4.4A)
1BM  A 499 ( 3.7A)
 0.50A 3g5dA-2hk5A:
29.5		 3g5dA-2hk5A:
66.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2hz0 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		11 LEU A 248
VAL A 256
ALA A 269
GLU A 286
MET A 290
VAL A 299
ILE A 313
THR A 315
GLY A 321
LEU A 370
ALA A 380
 GIN  A 600 ( 4.6A)
GIN  A 600 ( 4.7A)
GIN  A 600 (-3.1A)
GIN  A 600 (-3.6A)
GIN  A 600 (-3.2A)
GIN  A 600 (-4.6A)
GIN  A 600 (-3.8A)
GIN  A 600 (-3.4A)
None
GIN  A 600 (-4.7A)
GIN  A 600 (-3.1A)
 0.66A 3g5dA-2hz0A:
32.9		 3g5dA-2hz0A:
48.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j0j FOCAL ADHESION
KINASE 1

(Gallus gallus) 		PF00373
(FERM_M)
PF07714
(Pkinase_Tyr) 		7 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
LEU A 553
 4ST  A1687 ( 4.8A)
4ST  A1687 (-3.3A)
4ST  A1687 ( 4.6A)
None
None
None
4ST  A1687 (-4.4A)
 0.59A 3g5dA-2j0jA:
32.6		 3g5dA-2j0jA:
18.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2jkm FOCAL ADHESION
KINASE 1

(Gallus gallus) 		PF07714
(Pkinase_Tyr) 		8 VAL A 436
ALA A 452
GLU A 471
MET A 475
VAL A 484
ILE A 497
GLY A 505
LEU A 553
 BII  A1687 ( 4.7A)
BII  A1687 (-3.5A)
None
None
None
None
BII  A1687 (-3.6A)
BII  A1687 (-4.2A)
 0.75A 3g5dA-2jkmA:
32.5		 3g5dA-2jkmA:
39.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2og8 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		10 ALA A 271
GLU A 288
MET A 292
VAL A 301
ILE A 314
THR A 316
TYR A 318
GLY A 322
LEU A 371
ALA A 381
 1N8  A 501 ( 3.4A)
1N8  A 501 ( 3.6A)
1N8  A 501 ( 3.6A)
None
1N8  A 501 ( 4.6A)
1N8  A 501 ( 3.3A)
1N8  A 501 ( 3.7A)
1N8  A 501 ( 3.5A)
1N8  A 501 ( 4.3A)
1N8  A 501 ( 3.3A)
 0.72A 3g5dA-2og8A:
34.1		 3g5dA-2og8A:
67.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2og8 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		9 LEU A 251
ALA A 271
GLU A 288
MET A 292
VAL A 301
ILE A 314
THR A 316
TYR A 318
ALA A 381
 None
1N8  A 501 ( 3.4A)
1N8  A 501 ( 3.6A)
1N8  A 501 ( 3.6A)
None
1N8  A 501 ( 4.6A)
1N8  A 501 ( 3.3A)
1N8  A 501 ( 3.7A)
1N8  A 501 ( 3.3A)
 0.53A 3g5dA-2og8A:
34.1		 3g5dA-2og8A:
67.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2og8 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 251
VAL A 259
ALA A 271
GLU A 288
MET A 292
ILE A 314
THR A 316
TYR A 318
 None
None
1N8  A 501 ( 3.4A)
1N8  A 501 ( 3.6A)
1N8  A 501 ( 3.6A)
1N8  A 501 ( 4.6A)
1N8  A 501 ( 3.3A)
1N8  A 501 ( 3.7A)
 0.47A 3g5dA-2og8A:
34.1		 3g5dA-2og8A:
67.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ogv MACROPHAGE
COLONY-STIMULATING
FACTOR 1 RECEPTOR
PRECURSOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		10 LEU A 588
VAL A 596
ALA A 614
GLU A 633
MET A 637
VAL A 647
THR A 663
TYR A 665
GLY A 669
LEU A 785
 None
 0.75A 3g5dA-2ogvA:
29.0		 3g5dA-2ogvA:
34.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2psq FIBROBLAST GROWTH
FACTOR RECEPTOR 2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		9 LEU A 487
VAL A 495
ALA A 515
GLU A 534
MET A 538
TYR A 566
GLY A 570
LEU A 633
ALA A 643
 None
 0.53A 3g5dA-2psqA:
32.5		 3g5dA-2psqA:
32.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qlu ACTIVIN RECEPTOR
TYPE IIB

(Homo sapiens) 		PF00069
(Pkinase) 		7 VAL A 204
ALA A 215
GLU A 230
THR A 265
GLY A 271
LEU A 328
ALA A 338
 ADE  A 488 ( 4.9A)
ADE  A 488 (-3.2A)
None
ADE  A 488 (-4.3A)
ADE  A 488 ( 4.1A)
ADE  A 488 (-4.4A)
None
 0.52A 3g5dA-2qluA:
26.5		 3g5dA-2qluA:
26.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2r2p EPHRIN TYPE-A
RECEPTOR 5

(Homo sapiens) 		PF07714
(Pkinase_Tyr)
PF14575
(EphA2_TM) 		9 VAL A 689
ALA A 705
GLU A 724
MET A 728
ILE A 751
THR A 753
TYR A 755
GLY A 759
LEU A 807
 None
 0.74A 3g5dA-2r2pA:
33.7		 3g5dA-2r2pA:
42.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xik SERINE/THREONINE
PROTEIN KINASE 25

(Homo sapiens) 		PF00069
(Pkinase) 		7 VAL A  34
ALA A  47
GLU A  66
ILE A  93
GLY A 101
LEU A 147
ALA A 157
 J60  A1294 ( 4.9A)
J60  A1294 (-3.3A)
None
None
J60  A1294 ( 3.8A)
J60  A1294 (-4.8A)
J60  A1294 ( 4.2A)
 0.55A 3g5dA-2xikA:
21.0		 3g5dA-2xikA:
29.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xik SERINE/THREONINE
PROTEIN KINASE 25

(Homo sapiens) 		PF00069
(Pkinase) 		7 VAL A  34
ALA A  47
GLU A  66
ILE A  93
TYR A  97
GLY A 101
ALA A 157
 J60  A1294 ( 4.9A)
J60  A1294 (-3.3A)
None
None
J60  A1294 (-4.5A)
J60  A1294 ( 3.8A)
J60  A1294 ( 4.2A)
 0.50A 3g5dA-2xikA:
21.0		 3g5dA-2xikA:
29.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2xyu EPHRIN TYPE-A
RECEPTOR 4,

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		8 VAL A 635
ALA A 651
MET A 674
ILE A 697
THR A 699
TYR A 701
GLY A 705
LEU A 753
 Q9G  A1898 ( 4.7A)
Q9G  A1898 (-3.2A)
Q9G  A1898 (-3.9A)
Q9G  A1898 ( 4.6A)
Q9G  A1898 (-3.5A)
Q9G  A1898 (-4.8A)
Q9G  A1898 ( 3.8A)
Q9G  A1898 (-4.3A)
 0.59A 3g5dA-2xyuA:
28.1		 3g5dA-2xyuA:
42.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2z8c INSULIN RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 LEU A1002
VAL A1010
ALA A1028
GLU A1047
MET A1051
VAL A1060
GLY A1082
 S91  A   1 ( 4.1A)
S91  A   1 ( 4.9A)
S91  A   1 (-3.2A)
None
None
None
S91  A   1 (-3.3A)
 0.51A 3g5dA-2z8cA:
30.5		 3g5dA-2z8cA:
37.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zv7 TYROSINE-PROTEIN
KINASE LYN

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		10 LEU A 253
VAL A 261
ALA A 273
GLU A 290
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
ALA A 384
 None
 0.68A 3g5dA-2zv7A:
36.1		 3g5dA-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2zv7 TYROSINE-PROTEIN
KINASE LYN

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		10 LEU A 253
VAL A 261
ALA A 273
MET A 294
VAL A 303
ILE A 317
THR A 319
GLY A 325
LEU A 374
ALA A 384
 None
 0.68A 3g5dA-2zv7A:
36.1		 3g5dA-2zv7A:
64.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3b2t FIBROBLAST GROWTH
FACTOR RECEPTOR 2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		9 LEU A 487
VAL A 495
ALA A 515
GLU A 534
MET A 538
TYR A 566
GLY A 570
LEU A 633
ALA A 643
 M33  A1996 (-4.0A)
M33  A1996 ( 4.7A)
M33  A1996 (-3.3A)
None
None
M33  A1996 ( 4.7A)
M33  A1996 ( 4.8A)
M33  A1996 (-4.5A)
None
 0.55A 3g5dA-3b2tA:
25.8		 3g5dA-3b2tA:
36.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3d7u TYROSINE-PROTEIN
KINASE CSK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		10 VAL A 209
ALA A 220
GLU A 236
MET A 240
VAL A 249
ILE A 264
THR A 266
TYR A 268
GLY A 272
LEU A 321
 None
 0.49A 3g5dA-3d7uA:
28.2		 3g5dA-3d7uA:
41.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3hng VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 LEU A 833
VAL A 841
ALA A 859
GLU A 878
VAL A 892
TYR A 911
LEU A1029
 8ST  A2001 ( 4.7A)
8ST  A2001 ( 4.6A)
8ST  A2001 ( 3.8A)
8ST  A2001 (-3.7A)
8ST  A2001 ( 4.7A)
8ST  A2001 (-4.9A)
None
 0.58A 3g5dA-3hngA:
29.8		 3g5dA-3hngA:
31.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iec SERINE/THREONINE-PRO
TEIN KINASE MARK2

(Homo sapiens) 		PF00069
(Pkinase)
PF00627
(UBA) 		7 ALA A  80
MET A 104
VAL A 113
TYR A 131
GLY A 135
LEU A 182
ALA A 192
 None
 0.58A 3g5dA-3iecA:
24.2		 3g5dA-3iecA:
27.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kex RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 696
VAL A 704
VAL A 753
THR A 768
TYR A 770
GLY A 774
LEU A 822
ALA A 832
 ANP  A   1 (-4.4A)
ANP  A   1 (-3.9A)
None
ANP  A   1 ( 4.8A)
ANP  A   1 (-4.3A)
ANP  A   1 ( 4.9A)
ANP  A   1 (-4.7A)
None
 0.55A 3g5dA-3kexA:
28.5		 3g5dA-3kexA:
33.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3kul EPHRIN TYPE-A
RECEPTOR 8

(Homo sapiens) 		PF07714
(Pkinase_Tyr)
PF14575
(EphA2_TM) 		7 ALA A 665
MET A 688
ILE A 711
THR A 713
TYR A 715
GLY A 719
LEU A 767
 None
None
None
None
GOL  A 403 (-4.1A)
GOL  A 403 (-3.4A)
None
 0.53A 3g5dA-3kulA:
34.2		 3g5dA-3kulA:
38.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mdy BONE MORPHOGENETIC
PROTEIN RECEPTOR
TYPE-1B

(Homo sapiens) 		PF07714
(Pkinase_Tyr)
PF08515
(TGF_beta_GS) 		8 VAL A 218
ALA A 229
GLU A 244
THR A 279
TYR A 281
GLY A 285
LEU A 339
ALA A 349
 LDN  A   1 ( 4.8A)
LDN  A   1 (-3.6A)
None
LDN  A   1 (-3.8A)
LDN  A   1 ( 4.8A)
LDN  A   1 (-3.3A)
LDN  A   1 (-4.5A)
LDN  A   1 ( 3.8A)
 0.57A 3g5dA-3mdyA:
26.5		 3g5dA-3mdyA:
27.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 VAL A 216
ALA A 227
GLU A 242
THR A 277
TYR A 279
GLY A 283
LEU A 337
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
None
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
 0.60A 3g5dA-3my0A:
26.4		 3g5dA-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3my0 SERINE/THREONINE-PRO
TEIN KINASE RECEPTOR
R3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 VAL A 216
ALA A 227
THR A 277
TYR A 279
GLY A 283
LEU A 337
ALA A 347
 LDN  A 600 (-4.5A)
LDN  A 600 (-3.2A)
LDN  A 600 (-4.0A)
LDN  A 600 (-4.7A)
LDN  A 600 (-3.3A)
LDN  A 600 (-4.6A)
LDN  A 600 ( 3.8A)
 0.59A 3g5dA-3my0A:
26.4		 3g5dA-3my0A:
27.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nyo G PROTEIN-COUPLED
RECEPTOR KINASE 6

(Homo sapiens) 		PF00069
(Pkinase)
PF00615
(RGS) 		7 LEU A 192
VAL A 200
ALA A 213
GLU A 234
VAL A 247
GLY A 269
LEU A 318
 AMP  A 577 ( 4.3A)
AMP  A 577 (-4.3A)
AMP  A 577 (-3.4A)
None
None
None
AMP  A 577 (-4.8A)
 0.56A 3g5dA-3nyoA:
23.1		 3g5dA-3nyoA:
22.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ppz SERINE/THREONINE-PRO
TEIN KINASE CTR1

(Arabidopsis
thaliana) 		PF07714
(Pkinase_Tyr) 		8 ALA A 576
MET A 600
VAL A 609
ILE A 623
THR A 625
TYR A 627
GLY A 631
LEU A 683
 STU  A   1 (-3.3A)
None
None
None
STU  A   1 (-4.1A)
STU  A   1 (-4.4A)
STU  A   1 (-3.2A)
STU  A   1 (-4.3A)
 0.39A 3g5dA-3ppzA:
30.9		 3g5dA-3ppzA:
32.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ppz SERINE/THREONINE-PRO
TEIN KINASE CTR1

(Arabidopsis
thaliana) 		PF07714
(Pkinase_Tyr) 		8 VAL A 565
ALA A 576
VAL A 609
ILE A 623
THR A 625
TYR A 627
GLY A 631
LEU A 683
 STU  A   1 (-4.9A)
STU  A   1 (-3.3A)
None
None
STU  A   1 (-4.1A)
STU  A   1 (-4.4A)
STU  A   1 (-3.2A)
STU  A   1 (-4.3A)
 0.50A 3g5dA-3ppzA:
30.9		 3g5dA-3ppzA:
32.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q4t ACTIVIN RECEPTOR
TYPE-2A

(Homo sapiens) 		PF00069
(Pkinase) 		7 VAL A 206
ALA A 217
GLU A 232
THR A 267
GLY A 273
LEU A 329
ALA A 339
 TAK  A   2 ( 4.9A)
TAK  A   2 (-3.5A)
TAK  A   2 ( 4.9A)
TAK  A   2 (-3.5A)
TAK  A   2 (-3.6A)
TAK  A   2 (-4.6A)
TAK  A   2 ( 4.2A)
 0.56A 3g5dA-3q4tA:
25.8		 3g5dA-3q4tA:
26.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3sxs CYTOPLASMIC
TYROSINE-PROTEIN
KINASE BMX

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		10 LEU A 423
VAL A 431
ALA A 443
MET A 464
VAL A 473
ILE A 487
THR A 489
TYR A 491
GLY A 495
LEU A 543
 PP2  A   1 (-4.1A)
PP2  A   1 (-4.5A)
PP2  A   1 (-3.2A)
PP2  A   1 ( 4.3A)
None
PP2  A   1 (-3.6A)
PP2  A   1 (-3.3A)
PP2  A   1 ( 4.9A)
PP2  A   1 ( 4.2A)
PP2  A   1 (-4.6A)
 0.48A 3g5dA-3sxsA:
32.7		 3g5dA-3sxsA:
43.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3tt0 BASIC FIBROBLAST
GROWTH FACTOR
RECEPTOR 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 484
VAL A 492
ALA A 512
GLU A 531
MET A 535
TYR A 563
LEU A 630
ALA A 640
 07J  A   1 ( 4.3A)
07J  A   1 (-4.0A)
07J  A   1 (-3.5A)
07J  A   1 (-3.8A)
07J  A   1 (-3.8A)
07J  A   1 (-4.7A)
07J  A   1 ( 4.4A)
07J  A   1 (-3.2A)
 0.70A 3g5dA-3tt0A:
30.1		 3g5dA-3tt0A:
33.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v5q NT-3 GROWTH FACTOR
RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 LEU A 544
VAL A 552
ALA A 570
VAL A 601
TYR A 619
GLY A 623
LEU A 686
 0F4  A 902 ( 4.2A)
None
0F4  A 902 (-3.2A)
None
0F4  A 902 (-4.2A)
0F4  A 902 (-3.4A)
0F4  A 902 (-4.5A)
 0.54A 3g5dA-3v5qA:
26.1		 3g5dA-3v5qA:
34.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wig DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		7 LEU A  75
VAL A  83
ALA A  96
VAL A 128
ILE A 142
GLY A 150
LEU A 198
 ANP  A 401 (-3.8A)
ANP  A 401 ( 4.3A)
ANP  A 401 (-3.2A)
CHU  A 403 (-4.2A)
CHU  A 403 (-3.8A)
ANP  A 401 ( 4.3A)
ANP  A 401 (-4.8A)
 0.60A 3g5dA-3wigA:
22.6		 3g5dA-3wigA:
27.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3zfx EPHRIN TYPE-B
RECEPTOR 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 VAL A 633
ALA A 649
GLU A 668
MET A 672
ILE A 695
THR A 697
GLY A 703
LEU A 751
 None
 0.72A 3g5dA-3zfxA:
34.8		 3g5dA-3zfxA:
42.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4af3 AURORA KINASE B

(Homo sapiens) 		PF00069
(Pkinase) 		7 LEU A  83
VAL A  91
ALA A 104
TYR A 156
GLY A 160
LEU A 207
ALA A 217
 VX6  A 500 (-3.8A)
VX6  A 500 ( 4.8A)
VX6  A 500 (-3.4A)
VX6  A 500 (-4.2A)
VX6  A 500 (-3.3A)
VX6  A 500 (-4.6A)
VX6  A 500 ( 4.2A)
 0.59A 3g5dA-4af3A:
20.1		 3g5dA-4af3A:
23.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4agd VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 LEU A 840
VAL A 848
ALA A 866
GLU A 885
VAL A 899
GLY A 922
LEU A1035
 B49  A2000 (-3.7A)
None
B49  A2000 (-3.5A)
None
B49  A2000 ( 4.6A)
B49  A2000 ( 3.7A)
B49  A2000 (-4.5A)
 0.53A 3g5dA-4agdA:
29.5		 3g5dA-4agdA:
31.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4aw5 EPHRIN TYPE-B
RECEPTOR 4

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 VAL A 105
ALA A 121
GLU A 140
MET A 144
ILE A 167
THR A 169
GLY A 175
LEU A 223
 30K  A1365 ( 4.6A)
30K  A1365 (-3.2A)
None
None
None
30K  A1365 (-3.8A)
30K  A1365 (-3.5A)
30K  A1365 (-4.5A)
 0.73A 3g5dA-4aw5A:
28.1		 3g5dA-4aw5A:
42.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bc6 SERINE/THREONINE-PRO
TEIN KINASE 10

(Homo sapiens) 		PF00069
(Pkinase) 		8 LEU A  42
VAL A  50
ALA A  63
VAL A  94
ILE A 108
GLY A 116
LEU A 164
ALA A 174
 XZN  A1317 (-3.6A)
XZN  A1317 ( 4.7A)
XZN  A1317 (-3.5A)
XZN  A1317 (-4.4A)
XZN  A1317 (-4.4A)
XZN  A1317 ( 3.7A)
XZN  A1317 (-4.7A)
XZN  A1317 ( 4.3A)
 0.81A 3g5dA-4bc6A:
22.7		 3g5dA-4bc6A:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c02 ACTIVIN RECEPTOR
TYPE-1

(Homo sapiens) 		PF00069
(Pkinase)
PF08515
(TGF_beta_GS) 		7 VAL A 222
ALA A 233
GLU A 248
THR A 283
TYR A 285
GLY A 289
LEU A 343
 TAK  A1507 (-4.7A)
TAK  A1507 (-3.3A)
None
TAK  A1507 (-3.6A)
TAK  A1507 ( 4.6A)
TAK  A1507 (-3.5A)
TAK  A1507 (-4.7A)
 0.59A 3g5dA-4c02A:
26.5		 3g5dA-4c02A:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c02 ACTIVIN RECEPTOR
TYPE-1

(Homo sapiens) 		PF00069
(Pkinase)
PF08515
(TGF_beta_GS) 		7 VAL A 222
ALA A 233
THR A 283
TYR A 285
GLY A 289
LEU A 343
ALA A 353
 TAK  A1507 (-4.7A)
TAK  A1507 (-3.3A)
TAK  A1507 (-3.6A)
TAK  A1507 ( 4.6A)
TAK  A1507 (-3.5A)
TAK  A1507 (-4.7A)
TAK  A1507 ( 4.2A)
 0.50A 3g5dA-4c02A:
26.5		 3g5dA-4c02A:
28.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ckr EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 616
VAL A 624
ALA A 653
GLU A 672
MET A 676
THR A 701
TYR A 703
ALA A 783
 None
DI1  A1000 (-4.8A)
DI1  A1000 (-3.6A)
DI1  A1000 (-3.8A)
DI1  A1000 (-3.6A)
DI1  A1000 (-3.6A)
DI1  A1000 (-4.0A)
DI1  A1000 (-3.7A)
 0.70A 3g5dA-4ckrA:
29.1		 3g5dA-4ckrA:
35.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4crs SERINE/THREONINE-PRO
TEIN KINASE N2

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		8 LEU A 663
VAL A 671
ALA A 684
VAL A 721
TYR A 739
GLY A 743
LEU A 789
ALA A 799
 AGS  A1985 (-4.2A)
AGS  A1985 (-4.6A)
AGS  A1985 (-3.5A)
None
None
None
AGS  A1985 (-4.8A)
AGS  A1985 ( 4.5A)
 0.61A 3g5dA-4crsA:
17.8		 3g5dA-4crsA:
24.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4f4p TYROSINE-PROTEIN
KINASE SYK

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 377
VAL A 385
ALA A 400
GLU A 420
MET A 424
VAL A 433
GLY A 454
LEU A 501
 0SB  A 701 ( 3.9A)
0SB  A 701 (-4.0A)
0SB  A 701 (-3.3A)
None
None
None
0SB  A 701 (-3.5A)
0SB  A 701 (-4.4A)
 0.56A 3g5dA-4f4pA:
32.1		 3g5dA-4f4pA:
37.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fod ALK TYROSINE KINASE
RECEPTOR

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A1122
VAL A1130
ALA A1148
GLU A1167
VAL A1180
ILE A1194
GLY A1202
LEU A1256
 0UV  A1501 (-3.8A)
0UV  A1501 (-4.5A)
0UV  A1501 (-3.4A)
None
0UV  A1501 ( 4.9A)
None
0UV  A1501 (-3.6A)
0UV  A1501 (-4.6A)
 0.55A 3g5dA-4fodA:
25.7		 3g5dA-4fodA:
33.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hvi TYROSINE-PROTEIN
KINASE JAK3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 828
VAL A 836
ALA A 853
GLU A 871
VAL A 884
TYR A 904
LEU A 956
ALA A 966
 19S  A1201 (-3.9A)
19S  A1201 (-4.4A)
19S  A1201 (-3.3A)
None
None
19S  A1201 (-4.7A)
19S  A1201 (-4.5A)
19S  A1201 ( 4.1A)
 0.70A 3g5dA-4hviA:
25.8		 3g5dA-4hviA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4hvi TYROSINE-PROTEIN
KINASE JAK3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 828
VAL A 836
ALA A 853
VAL A 884
TYR A 904
GLY A 908
LEU A 956
ALA A 966
 19S  A1201 (-3.9A)
19S  A1201 (-4.4A)
19S  A1201 (-3.3A)
None
19S  A1201 (-4.7A)
19S  A1201 ( 3.8A)
19S  A1201 (-4.5A)
19S  A1201 ( 4.1A)
 0.61A 3g5dA-4hviA:
25.8		 3g5dA-4hviA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4k11 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC

(Homo sapiens) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		8 LEU A 273
VAL A 281
ALA A 293
VAL A 323
ILE A 336
TYR A 340
GLY A 344
LEU A 393
 0J9  A 601 (-4.0A)
0J9  A 601 (-4.4A)
0J9  A 601 (-3.3A)
None
0J9  A 601 (-4.4A)
0J9  A 601 ( 4.7A)
0J9  A 601 ( 4.1A)
0J9  A 601 (-4.5A)
 0.50A 3g5dA-4k11A:
33.8		 3g5dA-4k11A:
94.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4k11 PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC

(Homo sapiens) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		8 LEU A 273
VAL A 281
ALA A 293
VAL A 323
TYR A 340
GLY A 344
LEU A 393
ALA A 403
 0J9  A 601 (-4.0A)
0J9  A 601 (-4.4A)
0J9  A 601 (-3.3A)
None
0J9  A 601 ( 4.7A)
0J9  A 601 ( 4.1A)
0J9  A 601 (-4.5A)
0J9  A 601 (-3.5A)
 0.50A 3g5dA-4k11A:
33.8		 3g5dA-4k11A:
94.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4k33 FIBROBLAST GROWTH
FACTOR RECEPTOR 3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		9 LEU A 478
VAL A 486
ALA A 506
GLU A 525
MET A 529
TYR A 557
GLY A 561
LEU A 624
ALA A 634
 ACP  A 801 (-3.8A)
ACP  A 801 (-4.2A)
ACP  A 801 (-3.3A)
ACP  A 801 ( 4.8A)
None
None
ACP  A 801 ( 4.6A)
ACP  A 801 (-4.4A)
None
 0.53A 3g5dA-4k33A:
26.3		 3g5dA-4k33A:
35.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lg4 SERINE/THREONINE-PRO
TEIN KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		8 LEU A  33
VAL A  41
ALA A  54
MET A  74
VAL A  83
TYR A 101
GLY A 105
ALA A 163
 GOL  A 404 ( 3.6A)
GOL  A 404 (-4.5A)
GOL  A 404 ( 3.1A)
None
GOL  A 403 (-4.1A)
GOL  A 404 ( 4.9A)
GOL  A 404 (-3.6A)
GOL  A 403 ( 3.0A)
 0.60A 3g5dA-4lg4A:
18.4		 3g5dA-4lg4A:
28.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lg4 SERINE/THREONINE-PRO
TEIN KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		8 LEU A  33
VAL A  41
ALA A  54
VAL A  83
ILE A  97
TYR A 101
GLY A 105
ALA A 163
 GOL  A 404 ( 3.6A)
GOL  A 404 (-4.5A)
GOL  A 404 ( 3.1A)
GOL  A 403 (-4.1A)
None
GOL  A 404 ( 4.9A)
GOL  A 404 (-3.6A)
GOL  A 403 ( 3.0A)
 0.54A 3g5dA-4lg4A:
18.4		 3g5dA-4lg4A:
28.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4lgg PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC

(Gallus gallus) 		PF07714
(Pkinase_Tyr) 		10 LEU A 273
VAL A 281
ALA A 293
MET A 314
VAL A 323
ILE A 336
TYR A 340
GLY A 344
LEU A 393
ALA A 403
 VGG  A 601 (-3.2A)
VGG  A 601 ( 3.5A)
VGG  A 601 (-3.5A)
VGG  A 601 ( 3.6A)
VGG  A 601 ( 4.8A)
VGG  A 601 (-4.2A)
VGG  A 601 ( 4.0A)
VGG  A 601 ( 3.2A)
VGG  A 601 (-4.5A)
VGG  A 601 ( 4.2A)
 0.63A 3g5dA-4lggA:
37.6		 3g5dA-4lggA:
99.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4o27 SERINE/THREONINE-PRO
TEIN KINASE 24

(Homo sapiens) 		PF00069
(Pkinase) 		7 VAL B  38
ALA B  51
GLU B  70
ILE B  97
TYR B 101
LEU B 151
ALA B 161
 ADP  B 500 (-4.5A)
ADP  B 500 (-3.3A)
None
None
ADP  B 500 ( 4.7A)
ADP  B 500 (-4.7A)
None
 0.43A 3g5dA-4o27B:
20.3		 3g5dA-4o27B:
30.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o38 CYCLIN-G-ASSOCIATED
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		8 LEU A  46
VAL A  54
ALA A  67
GLU A  85
VAL A  99
THR A 123
GLY A 128
LEU A 180
 SIN  A 401 ( 3.9A)
None
SIN  A 401 ( 3.7A)
None
None
None
SIN  A 401 (-3.5A)
SIN  A 401 ( 4.5A)
 0.63A 3g5dA-4o38A:
21.3		 3g5dA-4o38A:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o38 CYCLIN-G-ASSOCIATED
KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		8 VAL A  54
ALA A  67
GLU A  85
MET A  89
VAL A  99
THR A 123
GLY A 128
LEU A 180
 None
SIN  A 401 ( 3.7A)
None
None
None
None
SIN  A 401 (-3.5A)
SIN  A 401 ( 4.5A)
 0.82A 3g5dA-4o38A:
21.3		 3g5dA-4o38A:
27.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4otd SERINE/THREONINE-PRO
TEIN KINASE N1

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		7 LEU A 627
VAL A 635
ALA A 648
VAL A 685
TYR A 703
GLY A 707
LEU A 753
 None
 0.55A 3g5dA-4otdA:
22.8		 3g5dA-4otdA:
26.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9z HUMAN PROTEIN KINASE
C THETA

(Homo sapiens) 		PF00069
(Pkinase)
PF00433
(Pkinase_C) 		7 LEU A 386
VAL A 394
ALA A 407
GLU A 428
TYR A 460
LEU A 511
ALA A 521
 PZW  A 801 (-3.9A)
PZW  A 801 (-4.6A)
PZW  A 801 (-3.5A)
None
None
PZW  A 801 (-4.8A)
PZW  A 801 ( 4.6A)
 0.52A 3g5dA-4q9zA:
16.8		 3g5dA-4q9zA:
24.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rt7 RECEPTOR-TYPE
TYROSINE-PROTEIN
KINASE FLT3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 616
VAL A 624
ALA A 642
GLU A 661
VAL A 675
TYR A 693
GLY A 697
LEU A 818
 P30  A1001 (-3.8A)
None
P30  A1001 (-3.4A)
P30  A1001 (-3.6A)
None
P30  A1001 (-4.1A)
P30  A1001 (-3.4A)
P30  A1001 (-4.6A)
 0.59A 3g5dA-4rt7A:
24.6		 3g5dA-4rt7A:
32.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ueu TYROSINE KINASE AS -
A COMMON ANCESTOR OF
SRC AND ABL

(synthetic
construct) 		PF07714
(Pkinase_Tyr) 		10 LEU A  14
VAL A  22
ALA A  35
GLU A  52
MET A  56
THR A  81
TYR A  83
GLY A  87
LEU A 136
ALA A 146
 ACP  A1264 ( 4.5A)
ACP  A1264 (-4.7A)
ACP  A1264 (-2.9A)
None
None
ACP  A1264 (-4.5A)
ACP  A1264 ( 4.5A)
ACP  A1264 (-3.5A)
ACP  A1264 ( 4.8A)
None
 0.66A 3g5dA-4ueuA:
35.3		 3g5dA-4ueuA:
62.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ueu TYROSINE KINASE AS -
A COMMON ANCESTOR OF
SRC AND ABL

(synthetic
construct) 		PF07714
(Pkinase_Tyr) 		11 LEU A  14
VAL A  22
ALA A  35
GLU A  52
VAL A  65
ILE A  79
THR A  81
TYR A  83
GLY A  87
LEU A 136
ALA A 146
 ACP  A1264 ( 4.5A)
ACP  A1264 (-4.7A)
ACP  A1264 (-2.9A)
None
None
None
ACP  A1264 (-4.5A)
ACP  A1264 ( 4.5A)
ACP  A1264 (-3.5A)
ACP  A1264 ( 4.8A)
None
 0.53A 3g5dA-4ueuA:
35.3		 3g5dA-4ueuA:
62.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wsq AP2-ASSOCIATED
PROTEIN KINASE 1

(Homo sapiens) 		PF00069
(Pkinase) 		8 LEU A  52
VAL A  60
ALA A  72
MET A  94
VAL A 104
ILE A 124
GLY A 132
LEU A 183
 KSA  A 405 ( 4.0A)
KSA  A 405 ( 4.9A)
KSA  A 405 (-3.2A)
None
None
None
KSA  A 405 (-3.5A)
KSA  A 405 (-4.6A)
 0.59A 3g5dA-4wsqA:
24.1		 3g5dA-4wsqA:
26.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xey TYROSINE-PROTEIN
KINASE ABL1

(Homo sapiens) 		no annotation 10 LEU B 267
VAL B 275
ALA B 288
MET B 309
VAL B 318
ILE B 332
THR B 334
GLY B 340
LEU B 389
ALA B 399
 1N1  B 601 (-3.7A)
1N1  B 601 ( 4.9A)
1N1  B 601 (-3.5A)
1N1  B 601 (-3.7A)
1N1  B 601 ( 4.3A)
1N1  B 601 (-4.1A)
1N1  B 601 (-3.3A)
1N1  B 601 (-3.5A)
1N1  B 601 (-4.3A)
1N1  B 601 (-3.5A)
 0.41A 3g5dA-4xeyB:
27.3		 3g5dA-4xeyB:
36.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xi2 TYROSINE-PROTEIN
KINASE BTK

(Mus musculus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		8 LEU A 408
VAL A 416
ALA A 428
VAL A 458
ILE A 472
THR A 474
GLY A 480
LEU A 528
 None
 0.76A 3g5dA-4xi2A:
24.3		 3g5dA-4xi2A:
28.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xi2 TYROSINE-PROTEIN
KINASE BTK

(Mus musculus) 		PF00017
(SH2)
PF00018
(SH3_1)
PF07714
(Pkinase_Tyr) 		8 LEU A 408
VAL A 416
ALA A 428
VAL A 458
ILE A 472
THR A 474
TYR A 476
GLY A 480
 None
 0.73A 3g5dA-4xi2A:
24.3		 3g5dA-4xi2A:
28.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4xuf RECEPTOR-TYPE
TYROSINE-PROTEIN
KINASE FLT3

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		8 LEU A 616
VAL A 624
ALA A 642
GLU A 661
VAL A 675
TYR A 693
GLY A 697
LEU A 818
 P30  A1001 (-4.0A)
P30  A1001 ( 4.8A)
P30  A1001 (-3.5A)
P30  A1001 (-3.1A)
None
P30  A1001 ( 4.4A)
P30  A1001 (-3.5A)
P30  A1001 (-4.3A)
 0.53A 3g5dA-4xufA:
24.3		 3g5dA-4xufA:
38.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y93 NON-SPECIFIC
PROTEIN-TYROSINE
KINASE,NON-SPECIFIC
PROTEIN-TYROSINE
KINASE

(Bos taurus) 		PF00169
(PH)
PF00779
(BTK)
PF07714
(Pkinase_Tyr) 		9 LEU A 408
VAL A 416
ALA A 428
VAL A 458
ILE A 472
THR A 474
TYR A 476
GLY A 480
LEU A 528
 746  A 702 (-3.8A)
746  A 702 ( 4.3A)
746  A 702 (-2.4A)
None
None
746  A 702 (-3.7A)
746  A 702 (-4.4A)
746  A 702 (-3.6A)
746  A 702 (-4.4A)
 0.44A 3g5dA-4y93A:
31.0		 3g5dA-4y93A:
26.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yff SERINE/THREONINE-PRO
TEIN KINASE TNNI3K

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 VAL A 477
ALA A 488
ILE A 537
THR A 539
TYR A 541
LEU A 595
ALA A 605
 None
4CV  A 801 (-3.5A)
None
4CV  A 801 (-2.8A)
4CV  A 801 (-3.9A)
4CV  A 801 (-4.4A)
4CV  A 801 ( 3.9A)
 0.63A 3g5dA-4yffA:
21.6		 3g5dA-4yffA:
27.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5a46 FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		9 LEU A 484
VAL A 492
ALA A 512
GLU A 531
MET A 535
TYR A 563
GLY A 567
LEU A 630
ALA A 640
 38O  A1769 (-3.2A)
38O  A1769 (-4.5A)
38O  A1769 (-3.6A)
EDO  A1766 (-4.1A)
EDO  A1766 (-3.5A)
38O  A1769 (-4.2A)
38O  A1769 (-3.4A)
38O  A1769 (-4.6A)
EDO  A1766 ( 4.4A)
 0.57A 3g5dA-5a46A:
30.5		 3g5dA-5a46A:
32.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5f1z NON-RECEPTOR
TYROSINE-PROTEIN
KINASE TYK2

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		7 LEU A 903
VAL A 911
ALA A 928
GLU A 947
TYR A 980
GLY A 984
LEU A1030
 5U3  A1200 (-3.8A)
5U3  A1200 ( 4.4A)
5U3  A1200 (-3.5A)
None
5U3  A1200 (-4.5A)
5U3  A1200 (-3.2A)
5U3  A1200 (-4.4A)
 0.53A 3g5dA-5f1zA:
29.8		 3g5dA-5f1zA:
33.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5grn PLATELET-DERIVED
GROWTH FACTOR
RECEPTOR ALPHA

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		11 LEU A 599
VAL A 607
ALA A 625
GLU A 644
MET A 648
VAL A 658
ILE A 672
THR A 674
TYR A 676
GLY A 680
LEU A 825
 748  A1001 (-3.8A)
748  A1001 ( 4.7A)
748  A1001 (-3.7A)
748  A1001 (-3.3A)
748  A1001 (-3.4A)
748  A1001 ( 4.8A)
748  A1001 (-3.9A)
748  A1001 (-3.2A)
748  A1001 (-4.0A)
748  A1001 ( 4.0A)
748  A1001 (-4.3A)
 0.68A 3g5dA-5grnA:
25.3		 3g5dA-5grnA:
34.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz8 PROTEIN O-MANNOSE
KINASE

(Mus musculus) 		PF07714
(Pkinase_Tyr) 		8 VAL A  94
ALA A 105
VAL A 134
ILE A 146
THR A 148
TYR A 150
GLY A 154
LEU A 215
 None
 0.65A 3g5dA-5gz8A:
13.6		 3g5dA-5gz8A:
26.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gza PROTEIN O-MANNOSE
KINASE

(Danio rerio) 		PF07714
(Pkinase_Tyr) 		7 VAL A  93
ALA A 104
VAL A 133
THR A 147
TYR A 149
GLY A 153
LEU A 214
 ADP  A 401 (-4.4A)
ADP  A 401 (-3.2A)
None
ADP  A 401 ( 4.8A)
ADP  A 401 ( 4.8A)
ADP  A 401 ( 4.1A)
ADP  A 401 (-4.4A)
 0.48A 3g5dA-5gzaA:
20.0		 3g5dA-5gzaA:
28.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i3o BMP-2-INDUCIBLE
PROTEIN KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		8 LEU A  57
VAL A  65
ALA A  77
MET A  99
ILE A 128
TYR A 132
GLY A 136
LEU A 187
 IDV  A 401 (-3.8A)
IDV  A 401 (-4.6A)
IDV  A 401 (-3.6A)
None
None
IDV  A 401 (-3.5A)
IDV  A 401 (-3.4A)
IDV  A 401 (-4.4A)
 0.58A 3g5dA-5i3oA:
23.6		 3g5dA-5i3oA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i3o BMP-2-INDUCIBLE
PROTEIN KINASE

(Homo sapiens) 		PF00069
(Pkinase) 		8 LEU A  57
VAL A  65
ALA A  77
MET A  99
VAL A 109
TYR A 132
GLY A 136
LEU A 187
 IDV  A 401 (-3.8A)
IDV  A 401 (-4.6A)
IDV  A 401 (-3.6A)
None
None
IDV  A 401 (-3.5A)
IDV  A 401 (-3.4A)
IDV  A 401 (-4.4A)
 0.60A 3g5dA-5i3oA:
23.6		 3g5dA-5i3oA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j5t MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE KINASE
3

(Homo sapiens) 		PF00069
(Pkinase) 		7 VAL A  30
ALA A  43
GLU A  61
MET A  65
VAL A  74
ILE A  88
ALA A 153
 6G2  A 901 ( 4.9A)
6G2  A 901 (-3.2A)
None
None
None
None
6G2  A 901 ( 4.2A)
 0.59A 3g5dA-5j5tA:
23.0		 3g5dA-5j5tA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j5t MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE KINASE KINASE
3

(Homo sapiens) 		PF00069
(Pkinase) 		8 VAL A  30
ALA A  43
MET A  65
VAL A  74
ILE A  88
GLY A  96
LEU A 143
ALA A 153
 6G2  A 901 ( 4.9A)
6G2  A 901 (-3.2A)
None
None
None
6G2  A 901 (-3.6A)
6G2  A 901 (-4.7A)
6G2  A 901 ( 4.2A)
 0.51A 3g5dA-5j5tA:
23.0		 3g5dA-5j5tA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kbr SERINE/THREONINE-PRO
TEIN KINASE PAK 1

(Homo sapiens) 		PF00069
(Pkinase) 		7 VAL A 284
ALA A 297
MET A 319
VAL A 328
TYR A 346
GLY A 350
LEU A 396
 IPW  A 601 (-4.2A)
IPW  A 601 (-3.5A)
IPW  A 601 (-4.1A)
None
IPW  A 601 (-4.5A)
IPW  A 601 ( 3.8A)
IPW  A 601 (-4.5A)
 0.49A 3g5dA-5kbrA:
24.4		 3g5dA-5kbrA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u7q RHO-ASSOCIATED
PROTEIN KINASE 2

(Homo sapiens) 		PF00069
(Pkinase) 		7 VAL A 106
ALA A 119
GLU A 140
VAL A 153
TYR A 171
LEU A 221
ALA A 231
 None
 0.63A 3g5dA-5u7qA:
20.3		 3g5dA-5u7qA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u94 SERINE/THREONINE-PRO
TEIN KINASE PKNB

(Mycobacterium
tuberculosis) 		no annotation 7 LEU A  17
VAL A  25
ALA A  38
GLU A  59
VAL A  72
ILE A  90
TYR A  94
 G93  A 301 ( 3.8A)
G93  A 301 (-3.4A)
G93  A 301 ( 3.7A)
G93  A 301 (-3.2A)
G93  A 301 (-4.0A)
G93  A 301 ( 3.8A)
None
 0.54A 3g5dA-5u94A:
26.8		 3g5dA-5u94A:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w5j RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2

(Homo sapiens) 		no annotation 8 LEU A  24
VAL A  32
ALA A  45
ILE A  93
THR A  95
TYR A  97
GLY A 101
LEU A 153
 9WS  A 401 ( 4.2A)
9WS  A 401 ( 4.6A)
9WS  A 401 (-3.3A)
9WS  A 401 (-3.9A)
9WS  A 401 (-3.2A)
None
9WS  A 401 ( 4.3A)
9WS  A 401 (-4.6A)
 0.58A 3g5dA-5w5jA:
24.0		 3g5dA-5w5jA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w5j RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2

(Homo sapiens) 		no annotation 8 LEU A  24
VAL A  32
ALA A  45
THR A  95
TYR A  97
GLY A 101
LEU A 153
ALA A 163
 9WS  A 401 ( 4.2A)
9WS  A 401 ( 4.6A)
9WS  A 401 (-3.3A)
9WS  A 401 (-3.2A)
None
9WS  A 401 ( 4.3A)
9WS  A 401 (-4.6A)
9WS  A 401 ( 4.0A)
 0.64A 3g5dA-5w5jA:
24.0		 3g5dA-5w5jA:
28.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wno RECEPTOR
TYROSINE-PROTEIN
KINASE LET-23

(Caenorhabditis
elegans) 		no annotation 8 LEU A 891
VAL A 899
ALA A 917
ILE A 961
THR A 963
TYR A 965
GLY A 969
LEU A1017
 ANP  A1201 (-4.1A)
ANP  A1201 (-4.4A)
ANP  A1201 (-3.3A)
None
ANP  A1201 (-3.9A)
ANP  A1201 (-4.4A)
ANP  A1201 ( 4.6A)
ANP  A1201 (-4.7A)
 0.63A 3g5dA-5wnoA:
28.3		 3g5dA-5wnoA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ao5 SERINE/THREONINE-PRO
TEIN KINASE 3

(Homo sapiens) 		no annotation 9 LEU A  33
VAL A  41
ALA A  54
VAL A  83
ILE A  97
TYR A 101
GLY A 105
LEU A 153
ALA A 163
 ANP  A 501 ( 3.8A)
ANP  A 501 (-4.4A)
ANP  A 501 ( 3.7A)
None
None
ANP  A 501 ( 4.2A)
ANP  A 501 ( 4.0A)
ANP  A 501 (-4.6A)
None
 0.59A 3g5dA-6ao5A:
23.3		 3g5dA-6ao5A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c7y TYROSINE-PROTEIN
KINASE JAK1

(Homo sapiens) 		no annotation 7 LEU A 881
VAL A 889
ALA A 906
GLU A 925
VAL A 938
GLY A 962
LEU A1010
 ADP  A1201 ( 4.5A)
ADP  A1201 (-4.3A)
ADP  A1201 (-3.4A)
None
None
ADP  A1201 ( 4.1A)
ADP  A1201 (-4.5A)
 0.51A 3g5dA-6c7yA:
29.8		 3g5dA-6c7yA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fek PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET

(Homo sapiens) 		no annotation 7 LEU A 730
VAL A 738
ALA A 756
GLU A 775
TYR A 806
GLY A 810
LEU A 881
 ADN  A1104 ( 4.0A)
ADN  A1104 (-4.4A)
ADN  A1104 (-3.4A)
None
ADN  A1104 ( 4.1A)
ADN  A1104 ( 3.8A)
ADN  A1104 (-4.3A)
 0.45A 3g5dA-6fekA:
32.3		 3g5dA-6fekA:
13.75