SIMILAR PATTERNS OF AMINO ACIDS FOR 3G4L_A_ROFA901_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dcq PYK2-ASSOCIATED
PROTEIN BETA

(Mus musculus) 		PF01412
(ArfGap)
PF12796
(Ank_2) 		3 ASP A 307
LEU A 309
GLN A 437
 None
 0.71A 3g4lA-1dcqA:
undetectable		 3g4lA-1dcqA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eak 72 KDA TYPE IV
COLLAGENASE

(Homo sapiens) 		PF00040
(fn2)
PF00413
(Peptidase_M10)
PF01471
(PG_binding_1) 		3 ASP A 249
LEU A 257
GLN A 219
 None
 0.82A 3g4lA-1eakA:
undetectable		 3g4lA-1eakA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezv UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I

(Saccharomyces
cerevisiae) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C) 		3 ASP A 191
LEU A 192
GLN A 101
 None
 0.74A 3g4lA-1ezvA:
undetectable		 3g4lA-1ezvA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g8k ARSENITE OXIDASE
ARSENITE OXIDASE

(Alcaligenes
faecalis;
Alcaligenes
faecalis) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding)
PF00355
(Rieske) 		3 ASP A   5
LEU B 124
GLN A  57
 None
 0.70A 3g4lA-1g8kA:
undetectable		 3g4lA-1g8kA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl2 SYNTAXIN 7
VESICLE TRANSPORT
V-SNARE PROTEIN
VTI1-LIKE 1

(Mus musculus;
Mus musculus) 		PF05739
(SNARE)
PF12352
(V-SNARE_C) 		3 ASP B 191
LEU B 192
GLN C 170
 None
 0.73A 3g4lA-1gl2B:
undetectable		 3g4lA-1gl2B:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ii0 ARSENICAL
PUMP-DRIVING ATPASE

(Escherichia
coli) 		PF02374
(ArsA_ATPase) 		3 ASP A 417
LEU A 418
GLN A 430
 None
 0.69A 3g4lA-1ii0A:
undetectable		 3g4lA-1ii0A:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jog HYPOTHETICAL PROTEIN
HI0074

(Haemophilus
influenzae) 		PF08780
(NTase_sub_bind) 		3 ASP A  12
LEU A  11
GLN A  64
 None
 0.83A 3g4lA-1jogA:
undetectable		 3g4lA-1jogA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1moe ANTI-CEA MAB T84.66

(Mus musculus) 		PF07686
(V-set) 		3 ASP A  86
LEU A 108
GLN A   6
 None
 0.80A 3g4lA-1moeA:
undetectable		 3g4lA-1moeA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qfx PROTEIN (PH 2.5 ACID
PHOSPHATASE)

(Aspergillus
niger) 		PF00328
(His_Phos_2) 		3 ASP A 191
LEU A 432
GLN A 304
 None
NAG  A 596 (-4.7A)
GOL  A 703 (-4.0A)
 0.62A 3g4lA-1qfxA:
undetectable		 3g4lA-1qfxA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)

(Homo sapiens) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		3 ASP A 579
LEU A 583
GLN A 589
 None
 0.78A 3g4lA-1qgrA:
undetectable		 3g4lA-1qgrA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qnz 0.5B ANTIBODY (LIGHT
CHAIN)

(Mus musculus) 		PF07686
(V-set) 		3 ASP L  86
LEU L 108
GLN L   6
 None
 0.66A 3g4lA-1qnzL:
undetectable		 3g4lA-1qnzL:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qqf PROTEIN (COMPLEMENT
C3DG)

(Rattus
norvegicus) 		PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		3 ASP A1140
LEU A1143
GLN A1127
 None
 0.77A 3g4lA-1qqfA:
undetectable		 3g4lA-1qqfA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tzs CATHEPSIN E

(Homo sapiens) 		PF00026
(Asp) 		3 ASP A 290
LEU A 288
GLN A 245
 None
 0.67A 3g4lA-1tzsA:
undetectable		 3g4lA-1tzsA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uio ADENOSINE DEAMINASE

(Mus musculus) 		PF00962
(A_deaminase) 		3 ASP A 128
LEU A 132
GLN A 138
 None
 0.80A 3g4lA-1uioA:
undetectable		 3g4lA-1uioA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1x9s DNA POLYMERASE

(Escherichia
virus T7) 		PF00476
(DNA_pol_A) 		3 ASP A  65
LEU A  69
GLN A  76
 MG  A3001 ( 4.0A)
None
None
 0.81A 3g4lA-1x9sA:
undetectable		 3g4lA-1x9sA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a0l 33H1 FV FRAGMENT

(Mus musculus) 		PF07686
(V-set) 		3 ASP C  83
LEU C 104
GLN C   6
 None
 0.82A 3g4lA-2a0lC:
undetectable		 3g4lA-2a0lC:
14.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bi0 HYPOTHETICAL PROTEIN
RV0216

(Mycobacterium
tuberculosis) 		no annotation 3 ASP A 329
LEU A 328
GLN A 260
 None
 0.80A 3g4lA-2bi0A:
undetectable		 3g4lA-2bi0A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c27 MYCOTHIOL SYNTHASE

(Mycobacterium
tuberculosis) 		PF00583
(Acetyltransf_1) 		3 ASP A 163
LEU A 167
GLN A 180
 None
 0.72A 3g4lA-2c27A:
undetectable		 3g4lA-2c27A:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2coc FYVE, RHOGEF AND PH
DOMAIN CONTAINING
PROTEIN 3

(Homo sapiens) 		no annotation 3 ASP A  46
LEU A  49
GLN A  82
 None
 0.76A 3g4lA-2cocA:
undetectable		 3g4lA-2cocA:
15.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hg4 6-DEOXYERYTHRONOLIDE
B SYNTHASE

(Saccharopolyspora
erythraea) 		PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08990
(Docking)
PF16197
(KAsynt_C_assoc) 		3 ASP A 722
LEU A 721
GLN A 748
 None
 0.77A 3g4lA-2hg4A:
undetectable		 3g4lA-2hg4A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i3o GAMMA-GLUTAMYLTRANSF
ERASE RELATED
PROTEIN

(Thermoplasma
acidophilum) 		PF01019
(G_glu_transpept) 		3 ASP A 330
LEU A  54
GLN A 490
 None
 0.72A 3g4lA-2i3oA:
undetectable		 3g4lA-2i3oA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2inf UROPORPHYRINOGEN
DECARBOXYLASE

(Bacillus
subtilis) 		PF01208
(URO-D) 		3 ASP A 266
LEU A 265
GLN A 309
 None
 0.83A 3g4lA-2infA:
undetectable		 3g4lA-2infA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE

(Streptomyces
antibioticus) 		PF00201
(UDPGT) 		3 ASP A 317
LEU A 316
GLN A  34
 None
 0.63A 3g4lA-2iyaA:
undetectable		 3g4lA-2iyaA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jft SER-THR PHOSPHATASE
MSPP

(Mycolicibacterium
smegmatis) 		PF13672
(PP2C_2) 		3 ASP A  27
LEU A  30
GLN A 101
 None
 0.68A 3g4lA-2jftA:
undetectable		 3g4lA-2jftA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jg2 SERINE
PALMITOYLTRANSFERASE

(Sphingomonas
paucimobilis) 		PF00155
(Aminotran_1_2) 		3 ASP A 155
LEU A 201
GLN A 250
 None
 0.77A 3g4lA-2jg2A:
undetectable		 3g4lA-2jg2A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m7a UNCHARACTERIZED
PROTEIN

(Escherichia
coli) 		no annotation 3 ASP A  42
LEU A  30
GLN A  18
 None
 0.74A 3g4lA-2m7aA:
undetectable		 3g4lA-2m7aA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oew PROGRAMMED CELL
DEATH 6-INTERACTING
PROTEIN

(Homo sapiens) 		PF03097
(BRO1) 		3 ASP A  59
LEU A  58
GLN A   8
 None
 0.81A 3g4lA-2oewA:
undetectable		 3g4lA-2oewA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00106
(adh_short)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		3 ASP A 925
LEU A 926
GLN A 898
 None
 0.84A 3g4lA-2pffA:
undetectable		 3g4lA-2pffA:
11.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pk2 CYCLIN-T1, PROTEIN
TAT

(Homo sapiens;
Equine
infectious
anemia virus) 		PF00134
(Cyclin_N) 		3 ASP A  32
LEU A  35
GLN A 190
 ASP  A  32 ( 0.6A)
LEU  A  35 ( 0.6A)
GLN  A 190 ( 0.6A)
 0.59A 3g4lA-2pk2A:
undetectable		 3g4lA-2pk2A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qr6 IMP
DEHYDROGENASE/GMP
REDUCTASE

(Corynebacterium
glutamicum) 		PF00478
(IMPDH) 		3 ASP A 252
LEU A 251
GLN A 367
 None
 0.80A 3g4lA-2qr6A:
undetectable		 3g4lA-2qr6A:
19.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qyk CYCLIC AMP-SPECIFIC
PHOSPHODIESTERASE
HSPDE4A10

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 530
LEU A 531
GLN A 581
 ZN  A   1 (-2.5A)
None
NPV  A   3 (-3.1A)
 0.35A 3g4lA-2qykA:
51.8		 3g4lA-2qykA:
85.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qym PHOSPHODIESTERASE 4C

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 220
LEU A 226
GLN A 453
 None
 0.79A 3g4lA-2qymA:
43.1		 3g4lA-2qymA:
83.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uv8 FATTY ACID SYNTHASE
SUBUNIT BETA (FAS1)

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF01575
(MaoC_dehydratas)
PF08354
(DUF1729)
PF13452
(MaoC_dehydrat_N)
PF16073
(SAT) 		3 ASP G1791
LEU G1792
GLN G1659
 None
 0.82A 3g4lA-2uv8G:
undetectable		 3g4lA-2uv8G:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2woc ADP-RIBOSYL-[DINITRO
GEN REDUCTASE]
GLYCOHYDROLASE

(Rhodospirillum
rubrum) 		PF03747
(ADP_ribosyl_GH) 		3 ASP A  21
LEU A  17
GLN A 283
 None
 0.63A 3g4lA-2wocA:
undetectable		 3g4lA-2wocA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wrg HEMAGGLUTININ HA2
CHAIN

(Influenza A
virus) 		PF00509
(Hemagglutinin) 		3 ASP I 586
LEU I 589
GLN I 562
 None
 0.83A 3g4lA-2wrgI:
undetectable		 3g4lA-2wrgI:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn1 ALPHA-GALACTOSIDASE

(Lactobacillus
acidophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		3 ASP A  56
LEU A  55
GLN A 272
 None
 0.83A 3g4lA-2xn1A:
undetectable		 3g4lA-2xn1A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xr1 CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
100 KD SUBUNIT

(Methanosarcina
mazei) 		PF07521
(RMMBL)
PF07650
(KH_2)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		3 ASP A 279
LEU A 275
GLN A 422
 None
 0.74A 3g4lA-2xr1A:
undetectable		 3g4lA-2xr1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xub DNA-DIRECTED RNA
POLYMERASE III
SUBUNIT RPC3

(Homo sapiens) 		PF05645
(RNA_pol_Rpc82)
PF08221
(HTH_9) 		3 ASP A 318
LEU A 320
GLN A 371
 None
 0.79A 3g4lA-2xubA:
undetectable		 3g4lA-2xubA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ycb CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR

(Methanothermobacter
thermautotrophicus) 		PF07521
(RMMBL)
PF10996
(Beta-Casp)
PF16661
(Lactamase_B_6)
PF17214
(KH_7) 		3 ASP A 279
LEU A 275
GLN A 422
 None
 0.79A 3g4lA-2ycbA:
undetectable		 3g4lA-2ycbA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zqq METHYLGLUTACONYL-COA
HYDRATASE

(Homo sapiens) 		PF00378
(ECH_1) 		3 ASP A 273
LEU A 274
GLN A 281
 None
 0.80A 3g4lA-2zqqA:
undetectable		 3g4lA-2zqqA:
24.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2r CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 764
LEU A 765
GLN A 775
 None
VDN  A   1 ( 4.7A)
VDN  A   1 ( 4.4A)
 0.68A 3g4lA-3b2rA:
31.3		 3g4lA-3b2rA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2r CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 764
LEU A 765
GLN A 817
 None
VDN  A   1 ( 4.7A)
VDN  A   1 (-3.0A)
 0.50A 3g4lA-3b2rA:
31.3		 3g4lA-3b2rA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3beo UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Bacillus
anthracis) 		PF02350
(Epimerase_2) 		3 ASP A  49
LEU A  48
GLN A  70
 None
None
UD1  A 372 (-3.7A)
 0.73A 3g4lA-3beoA:
undetectable		 3g4lA-3beoA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bga BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 ASP A 452
LEU A 449
GLN A 189
 None
 0.78A 3g4lA-3bgaA:
undetectable		 3g4lA-3bgaA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjc CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 764
LEU A 765
GLN A 775
 ZN  A 876 (-2.5A)
WAN  A 901 ( 4.7A)
WAN  A 901 ( 4.6A)
 0.61A 3g4lA-3bjcA:
34.1		 3g4lA-3bjcA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjc CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 764
LEU A 765
GLN A 817
 ZN  A 876 (-2.5A)
WAN  A 901 ( 4.7A)
WAN  A 901 (-3.1A)
 0.48A 3g4lA-3bjcA:
34.1		 3g4lA-3bjcA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ciy TOLL-LIKE RECEPTOR 3

(Mus musculus) 		PF00560
(LRR_1)
PF13855
(LRR_8) 		3 ASP A 203
LEU A 177
GLN A 107
 None
 0.79A 3g4lA-3ciyA:
undetectable		 3g4lA-3ciyA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3a BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF01301
(Glyco_hydro_35) 		3 ASP A 462
LEU A 464
GLN A 400
 None
 0.83A 3g4lA-3d3aA:
undetectable		 3g4lA-3d3aA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dec BETA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 ASP A 428
LEU A 425
GLN A 165
 None
 0.77A 3g4lA-3decA:
undetectable		 3g4lA-3decA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dwm 9.5 KDA CULTURE
FILTRATE ANTIGEN
CFP10A

(Mycobacterium
tuberculosis) 		PF02597
(ThiS) 		3 ASP A  34
LEU A  35
GLN A  18
 None
 0.66A 3g4lA-3dwmA:
undetectable		 3g4lA-3dwmA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e02 UNCHARACTERIZED
PROTEIN DUF849

(Paraburkholderia
xenovorans) 		PF05853
(BKACE) 		3 ASP A  63
LEU A  66
GLN A  73
 None
 0.76A 3g4lA-3e02A:
undetectable		 3g4lA-3e02A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f1i HEPATOCYTE GROWTH
FACTOR-REGULATED
TYROSINE KINASE
SUBSTRATE

(Homo sapiens) 		PF12210
(Hrs_helical) 		3 ASP H 461
LEU H 465
GLN H 471
 None
 0.67A 3g4lA-3f1iH:
undetectable		 3g4lA-3f1iH:
15.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g4g CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 484
LEU A 485
GLN A 535
 ZN  A 801 (-2.6A)
None
D71  A 901 (-3.1A)
 0.29A 3g4lA-3g4gA:
52.5		 3g4lA-3g4gA:
74.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g6i PUTATIVE OUTER
MEMBRANE PROTEIN,
PART OF CARBOHYDRATE
BINDING COMPLEX

(Bacteroides
thetaiotaomicron) 		PF12875
(DUF3826) 		3 ASP A  51
LEU A  49
GLN A  41
 None
 0.80A 3g4lA-3g6iA:
undetectable		 3g4lA-3g6iA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hjv MALONYL COA-ACYL
CARRIER PROTEIN
TRANSACYLASE

(Vibrio cholerae) 		PF00698
(Acyl_transf_1) 		3 ASP A  26
LEU A  27
GLN A  84
 SO4  A 319 (-4.9A)
None
SO4  A 323 (-3.4A)
 0.81A 3g4lA-3hjvA:
undetectable		 3g4lA-3hjvA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iy5 ANTIBODY FRAGMENT
IGG2A (LIGHT CHAIN)

(Mus musculus) 		PF07686
(V-set) 		3 ASP A  83
LEU A 105
GLN A   6
 None
 0.80A 3g4lA-3iy5A:
undetectable		 3g4lA-3iy5A:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j1e CHAPERONIN BETA
SUBUNIT

(Acidianus
tengchongensis) 		PF00118
(Cpn60_TCP1) 		3 ASP A 157
LEU A 160
GLN A 499
 None
 0.59A 3g4lA-3j1eA:
undetectable		 3g4lA-3j1eA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jau HEAVY CHAIN OF FAB
FRAGMENT VARIABLE
REGION OF ANTIBODY
D5

(Mus musculus) 		PF07686
(V-set) 		3 ASP H  90
LEU H 114
GLN H   6
 None
 0.81A 3g4lA-3jauH:
undetectable		 3g4lA-3jauH:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mil ISOAMYL
ACETATE-HYDROLYZING
ESTERASE

(Saccharomyces
cerevisiae) 		PF13472
(Lipase_GDSL_2) 		3 ASP A 125
LEU A 185
GLN A  29
 None
 0.83A 3g4lA-3milA:
undetectable		 3g4lA-3milA:
18.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o57 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 392
LEU A 393
GLN A 443
 ZN  A   1 (-2.6A)
None
ZG2  A 506 (-3.3A)
 0.27A 3g4lA-3o57A:
51.6		 3g4lA-3o57A:
80.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ohm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-3

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 ASP B 227
LEU B 231
GLN B 245
 None
 0.80A 3g4lA-3ohmB:
undetectable		 3g4lA-3ohmB:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omb EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 1

(Bifidobacterium
longum) 		PF01547
(SBP_bac_1) 		3 ASP A 153
LEU A 421
GLN A  51
 None
 0.81A 3g4lA-3ombA:
undetectable		 3g4lA-3ombA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3one ADENOSYLHOMOCYSTEINA
SE

(Lupinus luteus) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		3 ASP A 142
LEU A 145
GLN A 215
 None
 0.75A 3g4lA-3oneA:
undetectable		 3g4lA-3oneA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r5e TRANSALDOLASE

(Corynebacterium
glutamicum) 		PF00923
(TAL_FSA) 		3 ASP A 118
LEU A 121
GLN A 184
 None
 0.83A 3g4lA-3r5eA:
undetectable		 3g4lA-3r5eA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rhg PUTATIVE
PHOPHOTRIESTERASE

(Proteus
mirabilis) 		PF02126
(PTE) 		3 ASP A 294
LEU A 257
GLN A  55
 CAC  A 370 (-2.4A)
None
None
 0.79A 3g4lA-3rhgA:
undetectable		 3g4lA-3rhgA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ry9 ANCESTRAL
GLUCOCORTICOID
RECEPTOR 1

(synthetic
construct) 		PF00104
(Hormone_recep) 		3 ASP A  60
LEU A  64
GLN A 230
 None
 0.80A 3g4lA-3ry9A:
undetectable		 3g4lA-3ry9A:
19.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3sl5 CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 318
LEU A 319
GLN A 369
 ASP  A 318 (-0.5A)
LEU  A 319 ( 0.6A)
GLN  A 369 (-0.6A)
 0.34A 3g4lA-3sl5A:
53.4		 3g4lA-3sl5A:
98.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t8l ADENINE DEAMINASE 2

(Agrobacterium
fabrum) 		PF01979
(Amidohydro_1)
PF13382
(Adenine_deam_C) 		3 ASP A  15
LEU A  18
GLN A  30
 None
 0.77A 3g4lA-3t8lA:
undetectable		 3g4lA-3t8lA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tgw V-TYPE ATP SYNTHASE
BETA CHAIN

(Methanosarcina
mazei) 		PF00006
(ATP-synt_ab)
PF02874
(ATP-synt_ab_N) 		3 ASP A 279
LEU A 280
GLN A 299
 None
 0.66A 3g4lA-3tgwA:
undetectable		 3g4lA-3tgwA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tni CYCLIN-T1

(Homo sapiens) 		PF00134
(Cyclin_N) 		3 ASP B  32
LEU B  35
GLN B 190
 None
 0.73A 3g4lA-3tniB:
undetectable		 3g4lA-3tniB:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u44 ATP-DEPENDENT
HELICASE/NUCLEASE
SUBUNIT A

(Bacillus
subtilis) 		PF00580
(UvrD-helicase)
PF12705
(PDDEXK_1)
PF13361
(UvrD_C) 		3 ASP A 298
LEU A 301
GLN A 895
 None
 0.64A 3g4lA-3u44A:
undetectable		 3g4lA-3u44A:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u7v BETA-GALACTOSIDASE

(Caulobacter
vibrioides) 		PF02449
(Glyco_hydro_42) 		3 ASP A 315
LEU A 316
GLN A 365
 None
 0.77A 3g4lA-3u7vA:
undetectable		 3g4lA-3u7vA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uam CHITIN BINDING
DOMAIN

(Burkholderia
pseudomallei) 		PF03067
(LPMO_10) 		3 ASP A  39
LEU A  38
GLN A 207
 None
 0.75A 3g4lA-3uamA:
undetectable		 3g4lA-3uamA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ui7 CAMP AND
CAMP-INHIBITED CGMP
3',5'-CYCLIC
PHOSPHODIESTERASE
10A

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 674
LEU A 675
GLN A 726
 ZN  A 772 (-2.4A)
C1L  A   1 (-4.3A)
C1L  A   1 (-2.9A)
 0.41A 3g4lA-3ui7A:
38.0		 3g4lA-3ui7A:
27.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d7k SAM-DEPENDENT
METHYLTRANSFERASES

(Streptomyces
davaonensis) 		PF00891
(Methyltransf_2) 		3 ASP A  91
LEU A  92
GLN A 164
 None
 0.67A 3g4lA-4d7kA:
undetectable		 3g4lA-4d7kA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dxy CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		3 ASP A 173
LEU A 177
GLN A 183
 None
 0.77A 3g4lA-4dxyA:
undetectable		 3g4lA-4dxyA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e2i LARGE T ANTIGEN

(Macaca mulatta
polyomavirus 1) 		PF06431
(Polyoma_lg_T_C) 		3 ASP A 283
LEU A 345
GLN A 519
 None
 0.75A 3g4lA-4e2iA:
undetectable		 3g4lA-4e2iA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4f0j PROBABLE HYDROLYTIC
ENZYME

(Pseudomonas
aeruginosa) 		PF00561
(Abhydrolase_1) 		3 ASP A 243
LEU A 240
GLN A  48
 None
 0.56A 3g4lA-4f0jA:
undetectable		 3g4lA-4f0jA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fkz UDP-N-ACETYLGLUCOSAM
INE 2-EPIMERASE

(Bacillus
subtilis) 		PF02350
(Epimerase_2) 		3 ASP A  47
LEU A  46
GLN A  68
 None
None
UD1  A 401 (-3.9A)
 0.76A 3g4lA-4fkzA:
undetectable		 3g4lA-4fkzA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gax AMORPHA-4,11-DIENE
SYNTHASE

(Artemisia annua) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 ASP A  55
LEU A  54
GLN A  81
 None
 0.79A 3g4lA-4gaxA:
undetectable		 3g4lA-4gaxA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hl7 NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE

(Vibrio cholerae) 		PF04095
(NAPRTase) 		3 ASP A  56
LEU A  55
GLN A 115
 None
 0.77A 3g4lA-4hl7A:
undetectable		 3g4lA-4hl7A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htz CGMP-DEPENDENT
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 808
LEU A 809
GLN A 859
 ZN  A1001 (-2.5A)
None
None
 0.45A 3g4lA-4htzA:
38.5		 3g4lA-4htzA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igm 2-AMINO-3-CARBOXYMUC
ONATE-6-SEMIALDEHYDE
DECARBOXYLASE

(Homo sapiens) 		PF04909
(Amidohydro_2) 		3 ASP A  99
LEU A  96
GLN A 142
 None
 0.76A 3g4lA-4igmA:
undetectable		 3g4lA-4igmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4irn PROLYL-ACP
DEHYDROGENASE

([Oscillatoria]
sp. PCC 6506) 		PF00441
(Acyl-CoA_dh_1)
PF02770
(Acyl-CoA_dh_M)
PF02771
(Acyl-CoA_dh_N) 		3 ASP A  32
LEU A  28
GLN A 262
 None
 0.81A 3g4lA-4irnA:
undetectable		 3g4lA-4irnA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4itx CYSTATHIONINE
BETA-LYASE METC

(Escherichia
coli) 		PF01053
(Cys_Met_Meta_PP) 		3 ASP A 386
LEU A 387
GLN A 282
 None
 0.79A 3g4lA-4itxA:
undetectable		 3g4lA-4itxA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mfi SN-GLYCEROL-3-PHOSPH
ATE ABC TRANSPORTER
SUBSTRATE-BINDING
PROTEIN USPB

(Mycobacterium
tuberculosis) 		PF13416
(SBP_bac_8) 		3 ASP A 204
LEU A 205
GLN A 381
 None
 0.75A 3g4lA-4mfiA:
undetectable		 3g4lA-4mfiA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n30 PROTEIN DISULFIDE
ISOMERASE

(Pseudomonas
aeruginosa) 		PF13462
(Thioredoxin_4) 		3 ASP A 145
LEU A 144
GLN A 115
 None
 0.73A 3g4lA-4n30A:
undetectable		 3g4lA-4n30A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n3y RAB GTPASE-BINDING
EFFECTOR PROTEIN 1

(Homo sapiens) 		PF09311
(Rab5-bind) 		3 ASP B 577
LEU B 581
GLN B 587
 None
 0.81A 3g4lA-4n3yB:
undetectable		 3g4lA-4n3yB:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nfd PAIRED
IMMUNOGLOBULIN-LIKE
TYPE 2 RECEPTOR BETA

(Homo sapiens) 		PF07686
(V-set) 		3 ASP A  89
LEU A 117
GLN A   7
 None
 0.83A 3g4lA-4nfdA:
undetectable		 3g4lA-4nfdA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o6d NS1

(West Nile virus) 		PF00948
(Flavi_NS1) 		3 ASP B  24
LEU B 198
GLN B  66
 None
 0.77A 3g4lA-4o6dB:
undetectable		 3g4lA-4o6dB:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7w L-PROLINE
CIS-4-HYDROXYLASE

(Mesorhizobium
japonicum) 		PF05118
(Asp_Arg_Hydrox)
PF05373
(Pro_3_hydrox_C) 		3 ASP A  19
LEU A  23
GLN A  52
 None
 0.78A 3g4lA-4p7wA:
undetectable		 3g4lA-4p7wA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pj3 INTRON-BINDING
PROTEIN AQUARIUS

(Homo sapiens) 		PF13086
(AAA_11)
PF13087
(AAA_12)
PF16399
(Aquarius_N) 		3 ASP A1269
LEU A1299
GLN A1136
 None
 0.69A 3g4lA-4pj3A:
undetectable		 3g4lA-4pj3A:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9x COPPER HOMEOSTASIS
PROTEIN CUTC

(Bacillus
anthracis) 		PF03932
(CutC) 		3 ASP A 106
LEU A 107
GLN A  81
 CA  A 303 (-2.9A)
None
None
 0.81A 3g4lA-4r9xA:
undetectable		 3g4lA-4r9xA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ru5 TAILSPIKE GP27

(Pseudomonas
phage phi297) 		no annotation 3 ASP A 613
LEU A 620
GLN A 554
 None
 0.76A 3g4lA-4ru5A:
undetectable		 3g4lA-4ru5A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4win GMP SYNTHETASE

(Plasmodium
falciparum) 		PF00117
(GATase) 		3 ASP A  37
LEU A  12
GLN A  98
 None
 0.77A 3g4lA-4winA:
undetectable		 3g4lA-4winA:
20.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wzi CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B

(Homo sapiens) 		PF00233
(PDEase_I) 		3 ASP A 564
LEU A 565
GLN A 615
 ZN  A 801 (-2.5A)
None
None
 0.17A 3g4lA-4wziA:
52.2		 3g4lA-4wziA:
47.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmm NUCLEOPORIN NUP145

(Saccharomyces
cerevisiae) 		PF12110
(Nup96) 		3 ASP B 188
LEU B 191
GLN B 449
 None
 0.71A 3g4lA-4xmmB:
undetectable		 3g4lA-4xmmB:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0i 4-AMINOBUTYRATE
AMINOTRANSFERASE,
MITOCHONDRIAL

(Sus scrofa) 		PF00202
(Aminotran_3) 		3 ASP A 393
LEU A 394
GLN A 400
 None
 0.70A 3g4lA-4y0iA:
undetectable		 3g4lA-4y0iA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yj1 UNCHARACTERIZED
PROTEIN

(Trypanosoma
brucei) 		PF09818
(ABC_ATPase) 		3 ASP A 444
LEU A 445
GLN A 404
 None
 0.76A 3g4lA-4yj1A:
undetectable		 3g4lA-4yj1A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yzz TRAP TRANSPORTER
SOLUTE BINDING
PROTEIN

(Bordetella
bronchiseptica) 		PF03480
(DctP) 		3 ASP A 113
LEU A 110
GLN A 197
 None
 0.56A 3g4lA-4yzzA:
undetectable		 3g4lA-4yzzA:
20.67