SIMILAR PATTERNS OF AMINO ACIDS FOR 3G2O_A_SAMA500_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cjb PROTEIN
(HYPOXANTHINE-GUANIN
E
PHOSPHORIBOSYLTRANSF
ERASE)

(Plasmodium
falciparum) 		PF00156
(Pribosyltran) 		3 ARG A  80
GLU A 144
ASP A 148
 None
IRP  A 300 (-2.8A)
IRP  A 300 (-3.8A)
 0.89A 3g2oA-1cjbA:
undetectable		 3g2oA-1cjbA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1d8c MALATE SYNTHASE G

(Escherichia
coli) 		PF01274
(Malate_synthase) 		3 ARG A 338
GLU A 359
ASP A 279
 GLV  A2000 (-3.6A)
None
None
 0.87A 3g2oA-1d8cA:
0.2		 3g2oA-1d8cA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eov ASPARTYL-TRNA
SYNTHETASE

(Saccharomyces
cerevisiae) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		3 ARG A 112
GLU A 163
ASP A 238
 None
 0.80A 3g2oA-1eovA:
0.2		 3g2oA-1eovA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f4h BETA-GALACTOSIDASE

(Escherichia
coli) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N)
PF02929
(Bgal_small_N)
PF16353
(DUF4981) 		3 ARG A 352
GLU A 650
ASP A 671
 None
 0.84A 3g2oA-1f4hA:
undetectable		 3g2oA-1f4hA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g7c ELONGATION FACTOR
1-ALPHA

(Saccharomyces
cerevisiae) 		PF00009
(GTP_EFTU)
PF03143
(GTP_EFTU_D3)
PF03144
(GTP_EFTU_D2) 		3 ARG A 425
GLU A 135
ASP A 130
 None
 0.81A 3g2oA-1g7cA:
undetectable		 3g2oA-1g7cA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gl9 REVERSE GYRASE

(Archaeoglobus
fulgidus) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		3 ARG B 968
GLU B 777
ASP B 782
 None
 0.68A 3g2oA-1gl9B:
5.0		 3g2oA-1gl9B:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jke D-TYR-TRNATYR
DEACYLASE

(Escherichia
coli) 		PF02580
(Tyr_Deacylase) 		3 ARG A  48
GLU A  34
ASP A  84
 None
 0.65A 3g2oA-1jkeA:
undetectable		 3g2oA-1jkeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p8a PROTEIN TYROSINE
PHOSPHATASE

(Tritrichomonas
suis) 		PF01451
(LMWPc) 		3 ARG A  68
GLU A  22
ASP A  31
 None
 0.92A 3g2oA-1p8aA:
undetectable		 3g2oA-1p8aA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1po0 IRON(III) DICITRATE
TRANSPORT PROTEIN
FECA PRECURSOR

(Escherichia
coli) 		PF00593
(TonB_dep_Rec)
PF07715
(Plug) 		3 ARG A 196
GLU A 512
ASP A 452
 None
 0.79A 3g2oA-1po0A:
undetectable		 3g2oA-1po0A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1u2v ARP2/3 COMPLEX 34KDA
SUBUNIT
ARP2/3 COMPLEX 20KDA
SUBUNIT

(Bos taurus;
Bos taurus) 		PF04045
(P34-Arc)
PF05856
(ARPC4) 		3 ARG F 156
GLU F 145
ASP D 272
 None
 0.62A 3g2oA-1u2vF:
undetectable		 3g2oA-1u2vF:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1umf CHORISMATE SYNTHASE

(Helicobacter
pylori) 		PF01264
(Chorismate_synt) 		3 ARG A 144
GLU A 151
ASP A 166
 None
 0.89A 3g2oA-1umfA:
undetectable		 3g2oA-1umfA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1un9 DIHYDROXYACETONE
KINASE

(Citrobacter
freundii) 		PF02733
(Dak1)
PF02734
(Dak2) 		3 ARG A  39
GLU A  62
ASP A 299
 None
 0.80A 3g2oA-1un9A:
undetectable		 3g2oA-1un9A:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wws HYPOTHETICAL PROTEIN
TTHA1479

(Thermus
thermophilus) 		PF09123
(DUF1931) 		3 ARG A  75
GLU A 109
ASP A 102
 None
 0.81A 3g2oA-1wwsA:
undetectable		 3g2oA-1wwsA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y79 PEPTIDYL-DIPEPTIDASE
DCP

(Escherichia
coli) 		PF01432
(Peptidase_M3) 		3 ARG 1 248
GLU 1 576
ASP 1 586
 None
 0.74A 3g2oA-1y791:
undetectable		 3g2oA-1y791:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2avn UBIQUINONE/MENAQUINO
NE BIOSYNTHESIS
METHYLTRANSFERASE-RE
LATED PROTEIN

(Thermotoga
maritima) 		PF08241
(Methyltransf_11) 		3 ARG A 210
GLU A 222
ASP A 228
 PO4  A 249 (-4.5A)
None
None
 0.75A 3g2oA-2avnA:
15.9		 3g2oA-2avnA:
26.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gq3 MALATE SYNTHASE G

(Mycobacterium
tuberculosis) 		PF01274
(Malate_synthase) 		3 ARG A 339
GLU A 360
ASP A 280
 MLT  A 900 (-2.9A)
None
None
 0.88A 3g2oA-2gq3A:
undetectable		 3g2oA-2gq3A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h0a TRANSCRIPTIONAL
REGULATOR

(Thermus
thermophilus) 		PF13377
(Peripla_BP_3) 		3 ARG A 154
GLU A 321
ASP A 161
 None
 0.60A 3g2oA-2h0aA:
2.1		 3g2oA-2h0aA:
26.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2id5 LEUCINE RICH REPEAT
NEURONAL 6A

(Homo sapiens) 		PF07679
(I-set)
PF13306
(LRR_5)
PF13855
(LRR_8) 		3 ARG A  88
GLU A  60
ASP A  13
 None
 0.90A 3g2oA-2id5A:
undetectable		 3g2oA-2id5A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ivw PILP PILOT PROTEIN

(Neisseria
meningitidis) 		PF04351
(PilP) 		3 ARG A  96
GLU A 145
ASP A 149
 None
 0.80A 3g2oA-2ivwA:
undetectable		 3g2oA-2ivwA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l6l DNAJ HOMOLOG
SUBFAMILY C MEMBER
24

(Homo sapiens) 		PF00226
(DnaJ)
PF05207
(zf-CSL) 		3 ARG A  76
GLU A 127
ASP A 108
 None
 0.94A 3g2oA-2l6lA:
undetectable		 3g2oA-2l6lA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l7f PITUITARY HOMEOBOX 2

(Homo sapiens) 		PF00046
(Homeobox) 		3 ARG P  22
GLU P  17
ASP P  66
 None
 0.75A 3g2oA-2l7fP:
undetectable		 3g2oA-2l7fP:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lm9 BLO T 21 ALLERGEN

(Blomia
tropicalis) 		PF11642
(Blo-t-5) 		3 ARG A 108
GLU A 113
ASP A  48
 None
 0.89A 3g2oA-2lm9A:
undetectable		 3g2oA-2lm9A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ood BLR3880 PROTEIN

(Bradyrhizobium
diazoefficiens) 		PF01979
(Amidohydro_1) 		3 ARG A 156
GLU A 148
ASP A 112
 None
 0.94A 3g2oA-2oodA:
undetectable		 3g2oA-2oodA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pjr PROTEIN (HELICASE
PCRA)
PROTEIN (HELICASE
PCRA)

(Geobacillus
stearothermophilus;
Geobacillus
stearothermophilus) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C)
PF13361
(UvrD_C) 		3 ARG A  39
GLU B 571
ASP A 353
 None
 0.88A 3g2oA-2pjrA:
3.0		 3g2oA-2pjrA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qtk PROBABLE PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		3 ARG A  16
GLU A 347
ASP A 308
 None
 0.94A 3g2oA-2qtkA:
undetectable		 3g2oA-2qtkA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans) 		PF14498
(Glyco_hyd_65N_2) 		3 ARG A 337
GLU A 383
ASP A 466
 None
 0.94A 3g2oA-2rdyA:
undetectable		 3g2oA-2rdyA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vm6 BCL-2-RELATED
PROTEIN A1

(Homo sapiens) 		PF00452
(Bcl-2) 		3 ARG A  68
GLU A  96
ASP A  15
 None
 0.83A 3g2oA-2vm6A:
undetectable		 3g2oA-2vm6A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wan PULLULANASE

(Bacillus
acidopullulyticus) 		PF00128
(Alpha-amylase)
PF02922
(CBM_48) 		3 ARG A 756
GLU A 761
ASP A 815
 None
GOL  A1924 (-3.8A)
None
 0.93A 3g2oA-2wanA:
undetectable		 3g2oA-2wanA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0h PHOTOSYSTEM II CP43
PROTEIN

(Thermosynechococcus
vulcanus) 		PF00421
(PSII) 		3 ARG C 390
GLU C 300
ASP C 187
 None
 0.85A 3g2oA-3a0hC:
undetectable		 3g2oA-3a0hC:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cia COLD-ACTIVE
AMINOPEPTIDASE

(Colwellia
psychrerythraea) 		PF01433
(Peptidase_M1)
PF09127
(Leuk-A4-hydro_C) 		3 ARG A 214
GLU A 239
ASP A 257
 None
 0.86A 3g2oA-3ciaA:
undetectable		 3g2oA-3ciaA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddn D-3-PHOSPHOGLYCERATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00389
(2-Hacid_dh)
PF01842
(ACT)
PF02826
(2-Hacid_dh_C) 		3 ARG A 233
GLU A 209
ASP A 527
 None
 0.81A 3g2oA-3ddnA:
6.7		 3g2oA-3ddnA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eck PROTEIN
(HOMOPROTOCATECHUATE
2,3-DIOXYGENASE)

(Brevibacterium
fuscum) 		PF00903
(Glyoxalase) 		3 ARG A 293
GLU A 242
ASP A 260
 CL  A 501 (-4.3A)
None
None
 0.91A 3g2oA-3eckA:
undetectable		 3g2oA-3eckA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fgb UNCHARACTERIZED
PROTEIN Q89ZH8_BACTN

(Bacteroides
thetaiotaomicron) 		PF10282
(Lactonase) 		3 ARG A 347
GLU A 252
ASP A 170
 None
 0.86A 3g2oA-3fgbA:
undetectable		 3g2oA-3fgbA:
22.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g2p PCZA361.24

(Amycolatopsis
orientalis) 		PF13649
(Methyltransf_25) 		3 ARG A  76
GLU A  92
ASP A 122
 SAH  A 500 (-3.4A)
SAH  A 500 (-2.8A)
SAH  A 500 (-3.6A)
 0.12A 3g2oA-3g2pA:
35.3		 3g2oA-3g2pA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gdc MULTICOPPER OXIDASE

(Arthrobacter
sp. FB24) 		PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A  82
GLU A 175
ASP A 173
 None
 0.90A 3g2oA-3gdcA:
undetectable		 3g2oA-3gdcA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gkb PUTATIVE ENOYL-COA
HYDRATASE

(Streptomyces
avermitilis) 		PF00378
(ECH_1) 		3 ARG A  71
GLU A 265
ASP A 267
 None
 0.77A 3g2oA-3gkbA:
undetectable		 3g2oA-3gkbA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Schizosaccharomyces
pombe) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 ARG B 379
GLU B 683
ASP B 678
 None
 0.78A 3g2oA-3h0gB:
undetectable		 3g2oA-3h0gB:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h84 ATPASE GET3

(Saccharomyces
cerevisiae) 		PF02374
(ArsA_ATPase) 		3 ARG A 322
GLU A  87
ASP A  89
 None
 0.76A 3g2oA-3h84A:
undetectable		 3g2oA-3h84A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ham AMINOGLYCOSIDE
PHOSPHOTRANSFERASE

(Enterococcus
faecium) 		PF01636
(APH) 		3 ARG A  50
GLU A  56
ASP A 192
 None
None
LLL  A 500 (-2.8A)
 0.81A 3g2oA-3hamA:
undetectable		 3g2oA-3hamA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i45 TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN

(Rhodospirillum
rubrum) 		PF13458
(Peripla_BP_6) 		3 ARG A 170
GLU A 136
ASP A 356
 None
 0.76A 3g2oA-3i45A:
undetectable		 3g2oA-3i45A:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42
PRE-MRNA-SPLICING
FACTOR CWF14

(Schizosaccharomyces
pombe;
Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV)
PF01423
(LSM) 		3 ARG e   5
GLU A 136
ASP A  81
 None
 0.83A 3g2oA-3jb9e:
undetectable		 3g2oA-3jb9e:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kbu SPECTRIN BETA CHAIN,
ERYTHROCYTE

(Homo sapiens) 		PF00435
(Spectrin) 		3 ARG A1697
GLU A1703
ASP A1773
 None
 0.94A 3g2oA-3kbuA:
undetectable		 3g2oA-3kbuA:
25.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oep PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0988

(Thermus
thermophilus) 		PF02626
(CT_A_B)
PF02682
(CT_C_D) 		3 ARG A 259
GLU A 275
ASP A 419
 None
 0.68A 3g2oA-3oepA:
undetectable		 3g2oA-3oepA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oqn CATABOLITE CONTROL
PROTEIN A

(Bacillus
subtilis) 		PF00356
(LacI)
PF13377
(Peripla_BP_3) 		3 ARG A 279
GLU A 250
ASP A 225
 None
 0.88A 3g2oA-3oqnA:
undetectable		 3g2oA-3oqnA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pq1 POLY(A) RNA
POLYMERASE

(Homo sapiens) 		no annotation 3 ARG A  76
GLU A 215
ASP A 249
 None
 0.84A 3g2oA-3pq1A:
undetectable		 3g2oA-3pq1A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pta DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1

(Homo sapiens) 		PF00145
(DNA_methylase)
PF01426
(BAH)
PF02008
(zf-CXXC) 		3 ARG A1337
GLU A 704
ASP A 700
 None
 0.71A 3g2oA-3ptaA:
8.3		 3g2oA-3ptaA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxx CARVEOL
DEHYDROGENASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		3 ARG A  53
GLU A  73
ASP A  75
 None
None
NAD  A 284 (-3.7A)
 0.91A 3g2oA-3pxxA:
2.1		 3g2oA-3pxxA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbw ANHYDRO-N-ACETYLMURA
MIC ACID KINASE

(Pseudomonas
aeruginosa) 		PF03702
(AnmK) 		3 ARG A  58
GLU A  63
ASP A 127
 None
 0.64A 3g2oA-3qbwA:
undetectable		 3g2oA-3qbwA:
25.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sqw ATP-DEPENDENT RNA
HELICASE MSS116,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		3 ARG A 469
GLU A 340
ASP A 332
 ANP  A 800 (-2.7A)
None
None
 0.94A 3g2oA-3sqwA:
3.5		 3g2oA-3sqwA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3x1l CMR6

(Archaeoglobus
fulgidus) 		PF03787
(RAMPs) 		3 ARG H 104
GLU H 259
ASP H  65
 None
 0.88A 3g2oA-3x1lH:
undetectable		 3g2oA-3x1lH:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2q RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		3 ARG A 522
GLU A 544
ASP A 551
 None
 0.77A 3g2oA-4a2qA:
2.8		 3g2oA-4a2qA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2w RETINOIC ACID
INDUCIBLE PROTEIN I

(Anas
platyrhynchos) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF16739
(CARD_2) 		3 ARG A 522
GLU A 544
ASP A 551
 None
 0.84A 3g2oA-4a2wA:
undetectable		 3g2oA-4a2wA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4djf CORRINOID/IRON-SULFU
R PROTEIN LARGE
SUBUNIT

(Moorella
thermoacetica) 		PF03599
(CdhD)
PF04060
(FeS) 		3 ARG C 236
GLU C 276
ASP C 296
 None
 0.75A 3g2oA-4djfC:
undetectable		 3g2oA-4djfC:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ex4 MALATE SYNTHASE G

(Mycobacterium
leprae) 		PF01274
(Malate_synthase) 		3 ARG A 340
GLU A 365
ASP A 281
 MG  A 801 ( 4.3A)
None
None
 0.91A 3g2oA-4ex4A:
undetectable		 3g2oA-4ex4A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g2r ACCD6,
CARBOXYLTRANSFERASE
BETA-SUBUNIT OF
ACYL-COA CARBOXYLASE

(Mycobacterium
tuberculosis) 		PF01039
(Carboxyl_trans) 		3 ARG A 361
GLU A 426
ASP A 419
 None
 0.72A 3g2oA-4g2rA:
undetectable		 3g2oA-4g2rA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gah THIOESTERASE
SUPERFAMILY MEMBER 4

(Homo sapiens) 		PF03061
(4HBT) 		3 ARG A  75
GLU A 122
ASP A 116
 None
 0.87A 3g2oA-4gahA:
undetectable		 3g2oA-4gahA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gkh AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB

(Acinetobacter
baumannii) 		PF01636
(APH) 		3 ARG A  89
GLU A  68
ASP A 198
 None
None
KAN  A 301 (-3.0A)
 0.81A 3g2oA-4gkhA:
undetectable		 3g2oA-4gkhA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4igi COLLAGEN ALPHA3(VI)

(Mus musculus) 		PF00092
(VWA) 		3 ARG A1038
GLU A1139
ASP A1143
 None
 0.92A 3g2oA-4igiA:
undetectable		 3g2oA-4igiA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j6e UDP-2,3-DIACYLGLUCOS
AMINE
PYROPHOSPHATASE LPXI

(Caulobacter
vibrioides) 		PF06230
(DUF1009) 		3 ARG A 236
GLU A 182
ASP A 104
 None
UDG  A 301 (-3.9A)
UDG  A 301 (-3.0A)
 0.93A 3g2oA-4j6eA:
undetectable		 3g2oA-4j6eA:
29.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jxn OCTAPRENYL-DIPHOSPHA
TE SYNTHASE

(Roseobacter
denitrificans) 		PF00348
(polyprenyl_synt) 		3 ARG A 177
GLU A 189
ASP A 199
 None
 0.94A 3g2oA-4jxnA:
undetectable		 3g2oA-4jxnA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lnf GLUTAMINE SYNTHETASE

(Bacillus
subtilis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		3 ARG A 321
GLU A 189
ASP A 158
 None
GLN  A 503 ( 2.7A)
None
 0.81A 3g2oA-4lnfA:
undetectable		 3g2oA-4lnfA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n30 PROTEIN DISULFIDE
ISOMERASE

(Pseudomonas
aeruginosa) 		PF13462
(Thioredoxin_4) 		3 ARG A  78
GLU A  60
ASP A  63
 None
 0.92A 3g2oA-4n30A:
undetectable		 3g2oA-4n30A:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nkj HEMAGGLUTININ HA2

(Influenza B
virus) 		PF00509
(Hemagglutinin) 		3 ARG A  35
GLU A  42
ASP A 120
 None
 0.86A 3g2oA-4nkjA:
undetectable		 3g2oA-4nkjA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rh7 GREEN FLUORESCENT
PROTEIN/CYTOPLASMIC
DYNEIN 2 HEAVY CHAIN
1

(Homo sapiens;
synthetic
construct) 		PF03028
(Dynein_heavy)
PF07728
(AAA_5)
PF08393
(DHC_N2)
PF12774
(AAA_6)
PF12775
(AAA_7)
PF12777
(MT)
PF12780
(AAA_8)
PF12781
(AAA_9) 		3 ARG A2639
GLU A2525
ASP A2563
 None
 0.84A 3g2oA-4rh7A:
undetectable		 3g2oA-4rh7A:
6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4upl SULFATASE FAMILY
PROTEIN

(Ruegeria
pomeroyi) 		PF00884
(Sulfatase)
PF16347
(DUF4976) 		3 ARG A  60
GLU A 373
ASP A 413
 None
 0.82A 3g2oA-4uplA:
undetectable		 3g2oA-4uplA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uqz HSIE1
HSIB1

(Pseudomonas
aeruginosa;
Pseudomonas
aeruginosa) 		PF07024
(ImpE)
PF05591
(T6SS_VipA) 		3 ARG B  15
GLU A 273
ASP A 278
 None
 0.83A 3g2oA-4uqzB:
undetectable		 3g2oA-4uqzB:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wh3 N-ACETYLHEXOSAMINE
1-KINASE

(Bifidobacterium
longum) 		PF01636
(APH) 		3 ARG A 359
GLU A 274
ASP A 118
 None
 0.87A 3g2oA-4wh3A:
undetectable		 3g2oA-4wh3A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xa8 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE
NAD-BINDING

(Xanthobacter
autotrophicus) 		PF02826
(2-Hacid_dh_C) 		3 ARG A 119
GLU A 254
ASP A 275
 None
 0.93A 3g2oA-4xa8A:
7.3		 3g2oA-4xa8A:
25.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zhj MG-CHELATASE SUBUNIT
CHLH

(Synechocystis
sp. PCC 6803) 		PF02514
(CobN-Mg_chel)
PF11965
(DUF3479) 		3 ARG A 667
GLU A 404
ASP A 944
 None
 0.80A 3g2oA-4zhjA:
5.6		 3g2oA-4zhjA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zzq CELLULOSE
1,4-BETA-CELLOBIOSID
ASE

(Dictyostelium
discoideum) 		PF00840
(Glyco_hydro_7) 		3 ARG A 266
GLU A 216
ASP A 172
 None
 0.69A 3g2oA-4zzqA:
undetectable		 3g2oA-4zzqA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b3h PROTEIN SHORT-ROOT

(Arabidopsis
thaliana) 		PF03514
(GRAS) 		3 ARG B 529
GLU B 248
ASP B 488
 None
 0.90A 3g2oA-5b3hB:
5.7		 3g2oA-5b3hB:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dbj FADH2-DEPENDENT
HALOGENASE PLTA

(Pseudomonas
protegens) 		no annotation 3 ARG E  99
GLU E 102
ASP E 221
 None
 0.66A 3g2oA-5dbjE:
undetectable		 3g2oA-5dbjE:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5es6 LINEAR GRAMICIDIN
SYNTHASE SUBUNIT A

(Brevibacillus
parabrevis) 		PF00501
(AMP-binding)
PF00551
(Formyl_trans_N) 		3 ARG A 512
GLU A 536
ASP A 343
 None
 0.89A 3g2oA-5es6A:
undetectable		 3g2oA-5es6A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5es9 LINEAR GRAMICIDIN
SYNTHETASE SUBUNIT A

(Brevibacillus
parabrevis) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00551
(Formyl_trans_N)
PF13193
(AMP-binding_C) 		3 ARG A 512
GLU A 536
ASP A 343
 None
 0.88A 3g2oA-5es9A:
undetectable		 3g2oA-5es9A:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ful PROTEIN ARGININE
N-METHYLTRANSFERASE
2

(Mus musculus) 		PF05175
(MTS) 		3 ARG A 133
GLU A 232
ASP A 111
 SAH  A1446 (-2.7A)
CA  A1448 ( 4.5A)
None
 0.93A 3g2oA-5fulA:
6.9		 3g2oA-5fulA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4g VCP-LIKE ATPASE

(Thermoplasma
acidophilum) 		PF00004
(AAA)
PF02359
(CDC48_N)
PF02933
(CDC48_2) 		3 ARG A 416
GLU A 408
ASP A 401
 None
 0.92A 3g2oA-5g4gA:
3.1		 3g2oA-5g4gA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjq AMP-DEPENDENT
SYNTHETASE AND
LIGASE

(Streptomyces
sp. ML694-90F3) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 ARG A 106
GLU A 439
ASP A 425
 None
 0.85A 3g2oA-5jjqA:
undetectable		 3g2oA-5jjqA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jnf LINEAR GRAMICIDIN
SYNTHASE SUBUNIT A

(Brevibacillus
parabrevis) 		no annotation 3 ARG C 512
GLU C 536
ASP C 343
 None
 0.83A 3g2oA-5jnfC:
undetectable		 3g2oA-5jnfC:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kd5 METALLOPEPTIDASE

(Bacteroides
thetaiotaomicron) 		PF13402
(Peptidase_M60)
PF17291
(M60-like_N) 		3 ARG A 611
GLU A 756
ASP A 775
 None
 0.88A 3g2oA-5kd5A:
undetectable		 3g2oA-5kd5A:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd1 CAPSID PROTEIN

(Rosellinia
necatrix
quadrivirus 1) 		no annotation 3 ARG A 833
GLU A  79
ASP A 857
 None
 0.91A 3g2oA-5nd1A:
undetectable		 3g2oA-5nd1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nd7 KINESIN-LIKE PROTEIN
KIF20A

(Mus musculus) 		PF00225
(Kinesin) 		3 ARG C 422
GLU C 310
ASP C 460
 None
 0.90A 3g2oA-5nd7C:
undetectable		 3g2oA-5nd7C:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nx7 PENTALENENE SYNTHASE

(Streptomyces
clavuligerus) 		no annotation 3 ARG A 139
GLU A 194
ASP A 287
 None
 0.87A 3g2oA-5nx7A:
undetectable		 3g2oA-5nx7A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ny5 3,4-DIHYDROXYBENZOAT
E DECARBOXYLASE

(Enterobacter
cloacae) 		PF01977
(UbiD) 		3 ARG A 475
GLU A 480
ASP A 482
 None
 0.61A 3g2oA-5ny5A:
undetectable		 3g2oA-5ny5A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oas MALATE SYNTHASE G

(Pseudomonas
aeruginosa) 		no annotation 3 ARG A 340
GLU A 361
ASP A 281
 MG  A 820 (-3.8A)
None
EDO  A 814 (-3.6A)
 0.92A 3g2oA-5oasA:
undetectable		 3g2oA-5oasA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5olc GALACTONATE
DEHYDRATASE

(Zobellia
galactanivorans) 		no annotation 3 ARG A 190
GLU A 220
ASP A 269
 None
 0.81A 3g2oA-5olcA:
undetectable		 3g2oA-5olcA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5opg ENVELOPE
GLYCOPROTEIN GN

(Hantaan
orthohantavirus) 		PF01567
(Hanta_G1) 		3 ARG A 172
GLU A 371
ASP A 189
 None
 0.85A 3g2oA-5opgA:
undetectable		 3g2oA-5opgA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3e BACILLAMIDE
SYNTHETASE
HETEROCYCLIZATION
DOMAIN

(Thermoactinomyces
vulgaris) 		PF00668
(Condensation) 		3 ARG A 945
GLU A1244
ASP A1248
 None
 0.82A 3g2oA-5t3eA:
undetectable		 3g2oA-5t3eA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t3e BACILLAMIDE
SYNTHETASE
HETEROCYCLIZATION
DOMAIN

(Thermoactinomyces
vulgaris) 		PF00668
(Condensation) 		3 ARG A1109
GLU A1100
ASP A1271
 None
 0.81A 3g2oA-5t3eA:
undetectable		 3g2oA-5t3eA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8f ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Saccharomyces
cerevisiae) 		no annotation 3 ARG C 124
GLU C 121
ASP C  77
 None
 0.93A 3g2oA-5v8fC:
undetectable		 3g2oA-5v8fC:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5v8f ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Saccharomyces
cerevisiae) 		no annotation 3 ARG C 124
GLU C 121
ASP C  82
 None
 0.87A 3g2oA-5v8fC:
undetectable		 3g2oA-5v8fC:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vqi IMPORTIN SUBUNIT
ALPHA

(Neurospora
crassa) 		no annotation 3 ARG B 315
GLU B 396
ASP B 435
 None
 0.74A 3g2oA-5vqiB:
undetectable		 3g2oA-5vqiB:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wp5 PHOSPHOMETHYLETHANOL
AMINE
N-METHYLTRANSFERASE
2

(Arabidopsis
thaliana) 		no annotation 3 ARG A 180
GLU A 188
ASP A 234
 None
 0.84A 3g2oA-5wp5A:
17.0		 3g2oA-5wp5A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x0y TRANSCRIPTION
REGULATORY PROTEIN
SNF2

(Saccharomyces
cerevisiae) 		PF00176
(SNF2_N)
PF00271
(Helicase_C)
PF14619
(SnAC) 		3 ARG O1076
GLU O1120
ASP O1134
 None
 0.70A 3g2oA-5x0yO:
2.9		 3g2oA-5x0yO:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog RNA POLYMERASE II
THIRD LARGEST
SUBUNIT B44, PART OF
CENTRAL CORE
RNA POLYMERASE II
SUBUNIT B12.5
RNA POLYMERASE
SUBUNIT ABC10-ALPHA

(Komagataella
phaffii;
Komagataella
phaffii;
Komagataella
phaffii) 		PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L)
PF13656
(RNA_pol_L_2)
PF03604
(DNA_RNApol_7kD) 		3 ARG K  37
GLU C 166
ASP L  70
 None
 0.67A 3g2oA-5xogK:
undetectable		 3g2oA-5xogK:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r DNA-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT

(Homo sapiens) 		PF00454
(PI3_PI4_kinase)
PF02259
(FAT)
PF02260
(FATC)
PF08163
(NUC194) 		3 ARG C 746
GLU C 713
ASP C1388
 None
 0.81A 3g2oA-5y3rC:
undetectable		 3g2oA-5y3rC:
5.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yf0 -

(-) 		no annotation 3 ARG A 167
GLU A 229
ASP A 295
 SAM  A 505 (-4.0A)
SAM  A 505 (-2.9A)
SAM  A 505 (-3.6A)
 0.63A 3g2oA-5yf0A:
undetectable		 3g2oA-5yf0A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6anv ANTI-CRISPR PROTEIN
ACRF1 FUSED WITH
C-TERMINAL MBP TAG

(Escherichia
coli;
Pseudomonas
phage JBD30) 		no annotation 3 ARG A  75
GLU A 118
ASP A 138
 None
 0.90A 3g2oA-6anvA:
undetectable		 3g2oA-6anvA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6axe MALATE SYNTHASE G

(Mycobacterium
marinum) 		PF01274
(Malate_synthase) 		3 ARG A 339
GLU A 364
ASP A 280
 ACO  A 801 (-3.3A)
None
None
 0.90A 3g2oA-6axeA:
undetectable		 3g2oA-6axeA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bk7 ELONGATION FACTOR G

(Enterococcus
faecalis) 		no annotation 3 ARG A 300
GLU A 398
ASP A 404
 None
 0.60A 3g2oA-6bk7A:
undetectable		 3g2oA-6bk7A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cv7 -

(-) 		no annotation 3 ARG A 298
GLU A 137
ASP A 203
 None
CA  A 404 (-2.9A)
None
 0.94A 3g2oA-6cv7A:
undetectable		 3g2oA-6cv7A:
undetectable