SIMILAR PATTERNS OF AMINO ACIDS FOR 3FO7_A_IMNA301_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1aok VIPOXIN COMPLEX

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		4 HIS B  48
ASP B  49
TYR B  52
PRO B  68
 ACT  B 134 (-3.6A)
ACT  B 134 ( 4.9A)
None
None
 0.50A 3fo7A-1aokB:
20.9		 3fo7A-1aokB:
56.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bpq PHOSPHOLIPASE A2

(Bos taurus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CA  A 124 (-2.1A)
None
None
 0.37A 3fo7A-1bpqA:
18.0		 3fo7A-1bpqA:
39.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1bun BETA2-BUNGAROTOXIN

(Bungarus
multicinctus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
NA  A 121 (-2.6A)
None
None
 0.53A 3fo7A-1bunA:
17.2		 3fo7A-1bunA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1dpy PHOSPHOLIPASE A2

(Bungarus
caeruleus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
NA  A 150 (-2.5A)
None
None
 0.64A 3fo7A-1dpyA:
17.3		 3fo7A-1dpyA:
39.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1dpy PHOSPHOLIPASE A2

(Bungarus
caeruleus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  50
ASP A  49
TYR A  46
PRO A  37
 None
NA  A 150 (-2.5A)
None
None
 1.35A 3fo7A-1dpyA:
17.3		 3fo7A-1dpyA:
39.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dxy D-2-HYDROXYISOCAPROA
TE DEHYDROGENASE

(Lactobacillus
casei) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 HIS A 183
ASP A 187
TYR A 188
PRO A 178
 None
 1.49A 3fo7A-1dxyA:
undetectable		 3fo7A-1dxyA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ek2 EPOXIDE HYDROLASE

(Mus musculus) 		PF00561
(Abhydrolase_1)
PF13419
(HAD_2) 		4 HIS A 263
ASP A 290
TYR A 294
PRO A 461
 None
 1.32A 3fo7A-1ek2A:
undetectable		 3fo7A-1ek2A:
11.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1g0z PHOSPHOLIPASE A2

(Bungarus
caeruleus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
 0.69A 3fo7A-1g0zA:
17.1		 3fo7A-1g0zA:
39.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1g0z PHOSPHOLIPASE A2

(Bungarus
caeruleus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  50
ASP A  49
TYR A  46
PRO A  37
 None
 1.26A 3fo7A-1g0zA:
17.1		 3fo7A-1g0zA:
39.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gmz PHOSPHOLIPASE A2

(Bothrops
pirajai) 		PF00068
(Phospholip_A2_1) 		5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
 0.49A 3fo7A-1gmzA:
20.1		 3fo7A-1gmzA:
64.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1gp7 PHOSPHOLIPASE A2

(Ophiophagus
hannah) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CA  A1125 (-2.4A)
None
None
 0.56A 3fo7A-1gp7A:
16.9		 3fo7A-1gp7A:
35.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ijl PHOSPHOLIPASE A2

(Deinagkistrodon
acutus) 		PF00068
(Phospholip_A2_1) 		5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
CA  A 203 (-2.6A)
None
None
None
 0.91A 3fo7A-1ijlA:
20.8		 3fo7A-1ijlA:
52.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1jia PHOSPHOLIPASE A2

(Gloydius halys) 		PF00068
(Phospholip_A2_1) 		5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
LYS A  69
 None
CA  A 134 (-2.4A)
None
None
None
 0.81A 3fo7A-1jiaA:
22.0		 3fo7A-1jiaA:
61.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m8r PHOSPHOLIPASE A2

(Gloydius halys) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CD  A1001 (-2.4A)
None
None
 0.38A 3fo7A-1m8rA:
20.9		 3fo7A-1m8rA:
54.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1m8t PHOSPHOLIPASE A2

(Ophiophagus
hannah) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CA  A1001 (-2.1A)
None
None
 0.50A 3fo7A-1m8tA:
18.2		 3fo7A-1m8tA:
40.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mh2 PHOSPHOLIPASE A2

(Naja
sagittifera) 		PF00068
(Phospholip_A2_1) 		4 ASP A  49
TYR A  52
PRO A  63
LYS A  64
 ACY  A 302 (-3.4A)
None
None
ACY  A 302 (-2.7A)
 0.92A 3fo7A-1mh2A:
18.2		 3fo7A-1mh2A:
36.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mh2 PHOSPHOLIPASE A2

(Naja
sagittifera) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 ACY  A 302 (-3.4A)
ACY  A 302 (-3.4A)
None
None
 0.42A 3fo7A-1mh2A:
18.2		 3fo7A-1mh2A:
36.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1mh8 PHOSPHOLIPASE A2

(Naja
sagittifera) 		PF00068
(Phospholip_A2_1) 		5 HIS A  48
ASP A  49
TYR A  52
PRO A  63
LYS A  64
 None
 0.77A 3fo7A-1mh8A:
18.7		 3fo7A-1mh8A:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1oz6 PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CA  A 134 (-2.6A)
None
None
 0.40A 3fo7A-1oz6A:
20.7		 3fo7A-1oz6A:
56.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ozy PHOSPHOLIPASE A2

(Micropechis
ikaheca) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.52A 3fo7A-1ozyA:
15.5		 3fo7A-1ozyA:
37.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1p7o PHOSPHOLIPASE A2

(Micropechis
ikaheca) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.36A 3fo7A-1p7oA:
18.2		 3fo7A-1p7oA:
38.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1po8 PHOSPHOLIPASE A2

(Bungarus
caeruleus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 SHV  A 122 (-4.1A)
NA  A 121 (-2.4A)
None
None
 0.47A 3fo7A-1po8A:
17.4		 3fo7A-1po8A:
38.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pp2 CALCIUM-FREE
PHOSPHOLIPASE A2

(Crotalus atrox) 		no annotation 4 HIS R  48
ASP R  49
PRO R  68
LYS R  69
 None
 1.22A 3fo7A-1pp2R:
21.3		 3fo7A-1pp2R:
54.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pp2 CALCIUM-FREE
PHOSPHOLIPASE A2

(Crotalus atrox) 		no annotation 4 HIS R  48
ASP R  49
TYR R  52
PRO R  68
 None
 0.75A 3fo7A-1pp2R:
21.3		 3fo7A-1pp2R:
54.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1psh PHOSPHOLIPASE A2

(Naja naja) 		PF00068
(Phospholip_A2_1) 		4 HIS A  47
ASP A  48
TYR A  51
PRO A  62
 None
CA  A 120 (-2.0A)
None
None
 0.32A 3fo7A-1pshA:
18.2		 3fo7A-1pshA:
38.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1pwo PHOSPHOLIPASE A2

(Micropechis
ikaheca) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.65A 3fo7A-1pwoA:
17.6		 3fo7A-1pwoA:
36.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rms RIBONUCLEASE MS

(Aspergillus
phoenicis) 		PF00545
(Ribonuclease) 		4 HIS A  39
ASP A  36
TYR A  37
PRO A  59
 3GP  A 106 (-4.0A)
None
3GP  A 106 (-4.3A)
None
 1.50A 3fo7A-1rmsA:
undetectable		 3fo7A-1rmsA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uaa PROTEIN
(ATP-DEPENDENT DNA
HELICASE REP.)

(Escherichia
coli) 		PF00580
(UvrD-helicase)
PF13361
(UvrD_C) 		4 HIS A 335
ASP A 344
TYR A 342
PRO A 368
 None
 1.19A 3fo7A-1uaaA:
undetectable		 3fo7A-1uaaA:
10.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vap PHOSPHOLIPASE A2

(Agkistrodon
piscivorus) 		PF00068
(Phospholip_A2_1) 		5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
 0.66A 3fo7A-1vapA:
21.5		 3fo7A-1vapA:
60.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1vip PHOSPHOLIPASE A2

(Daboia russelii) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.45A 3fo7A-1vipA:
21.5		 3fo7A-1vipA:
57.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1y75 PHOSPHOLIPASE A2
ISOFORM 6

(Naja
sagittifera) 		PF00068
(Phospholip_A2_1) 		4 HIS B  48
ASP B  49
TYR B  52
PRO B  63
 None
 0.49A 3fo7A-1y75B:
18.0		 3fo7A-1y75B:
36.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1zl7 HYPOTENSIVE
PHOSPHOLIPASE A2

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 HIS A  47
ASP A  48
TYR A  51
PRO A  59
 None
CA  A1001 ( 2.3A)
None
None
 0.51A 3fo7A-1zl7A:
19.7		 3fo7A-1zl7A:
53.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e3j EPOXIDE HYDROLASE
EPHB

(Mycobacterium
tuberculosis) 		PF00561
(Abhydrolase_1) 		4 HIS A  34
ASP A  61
TYR A  65
PRO A 268
 None
 1.20A 3fo7A-2e3jA:
undetectable		 3fo7A-2e3jA:
15.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2h4c PHOSPHOLIPASE A2-II

(Daboia
siamensis) 		PF00068
(Phospholip_A2_1) 		4 HIS B  48
ASP B  49
TYR B  52
PRO B  68
 None
 0.42A 3fo7A-2h4cB:
19.1		 3fo7A-2h4cB:
55.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2h4c PHOSPHOLIPASE A2-III

(Daboia
siamensis) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
 0.79A 3fo7A-2h4cA:
20.2		 3fo7A-2h4cA:
55.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i1y RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 HIS A 748
ASP A 747
TYR A 746
PRO A 950
 None
 1.27A 3fo7A-2i1yA:
undetectable		 3fo7A-2i1yA:
16.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2osn PHOSPHOLIPASE A2
ISOFORM 3

(Bungarus
caeruleus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  63
 None
 0.99A 3fo7A-2osnA:
17.1		 3fo7A-2osnA:
36.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pan GLYOXYLATE
CARBOLIGASE

(Escherichia
coli) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 HIS A  40
ASP A   8
TYR A  12
PRO A 175
 None
 1.48A 3fo7A-2panA:
undetectable		 3fo7A-2panA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qep RECEPTOR-TYPE
TYROSINE-PROTEIN
PHOSPHATASE N2

(Homo sapiens) 		PF00102
(Y_phosphatase) 		4 HIS A 784
ASP A 783
TYR A 782
PRO A 986
 None
 1.29A 3fo7A-2qepA:
undetectable		 3fo7A-2qepA:
17.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2qhe PHOSPHOLIPASE A2

(Echis carinatus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
TYR A  52
PRO A  68
LYS A  69
 None
 0.46A 3fo7A-2qheA:
22.6		 3fo7A-2qheA:
66.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z6v PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF13469
(Sulfotransfer_3) 		4 HIS A  77
ASP A  76
TYR A  73
PRO A 126
 None
 1.47A 3fo7A-2z6vA:
undetectable		 3fo7A-2z6vA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cwx PROTEIN CAGD

(Helicobacter
pylori) 		PF16567
(CagD) 		4 HIS A  75
ASP A  72
TYR A 148
PRO A 150
 None
 1.22A 3fo7A-3cwxA:
undetectable		 3fo7A-3cwxA:
21.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3g8g PHOSPHOLIPASE A2,
AMMODYTOXIN A

(Vipera
ammodytes) 		PF00068
(Phospholip_A2_1) 		5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
 0.56A 3fo7A-3g8gA:
22.2		 3fo7A-3g8gA:
80.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3p2p PHOSPHOLIPASE A2

(Sus scrofa) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  68
 None
CA  A 125 (-2.1A)
None
None
 0.42A 3fo7A-3p2pA:
18.0		 3fo7A-3p2pA:
41.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tmg GLYCINE BETAINE,
L-PROLINE ABC
TRANSPORTER,
GLYCINE/BETAINE/L-PR
OLINE-BINDING
PROTEIN (PROX)

(Borreliella
burgdorferi) 		PF04069
(OpuAC) 		4 HIS A 240
ASP A 239
TYR A 236
PRO A 282
 None
 1.37A 3fo7A-3tmgA:
undetectable		 3fo7A-3tmgA:
17.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3v9m PHOSPHOLIPASE A2
ISOZYME PA-11

(Pseudechis
australis) 		PF00068
(Phospholip_A2_1) 		5 HIS A  48
ASP A  49
TYR A  52
PRO A  62
LYS A  63
 EDO  A 201 ( 4.0A)
CA  A 205 (-2.2A)
EDO  A 201 ( 4.8A)
None
PEG  A 206 (-2.2A)
 0.67A 3fo7A-3v9mA:
18.1		 3fo7A-3v9mA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3vbz PHOSPHOLIPASE A2
HOMOLOG, TAIPOXIN
BETA CHAIN

(Oxyuranus
scutellatus) 		PF00068
(Phospholip_A2_1) 		4 HIS A  48
ASP A  49
TYR A  52
PRO A  62
 None
 0.54A 3fo7A-3vbzA:
17.9		 3fo7A-3vbzA:
36.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fso PROBABLE PORIN

(Pseudomonas
aeruginosa) 		PF03573
(OprD) 		4 HIS A 172
ASP A 286
TYR A 284
PRO A 290
 None
 1.44A 3fo7A-4fsoA:
undetectable		 3fo7A-4fsoA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4haq GH7 FAMILY PROTEIN

(Limnoria
quadripunctata) 		PF00840
(Glyco_hydro_7) 		4 HIS A 291
ASP A 292
TYR A 286
PRO A 419
 None
 1.47A 3fo7A-4haqA:
undetectable		 3fo7A-4haqA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jnc BIFUNCTIONAL EPOXIDE
HYDROLASE 2

(Homo sapiens) 		PF00561
(Abhydrolase_1) 		4 HIS A 265
ASP A 292
TYR A 296
PRO A 462
 None
 1.21A 3fo7A-4jncA:
undetectable		 3fo7A-4jncA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nyq MILK PROTEIN

(Diploptera
punctata) 		no annotation 4 HIS A 103
TYR A 101
PRO A   3
LYS A   1
 GOL  A 210 ( 4.2A)
GOL  A 210 (-4.8A)
GOL  A 210 (-4.2A)
None
 1.13A 3fo7A-4nyqA:
undetectable		 3fo7A-4nyqA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q9d BENZOYLFORMATE
DECARBOXYLASE

(Mycolicibacterium
smegmatis) 		PF00205
(TPP_enzyme_M)
PF02775
(TPP_enzyme_C)
PF02776
(TPP_enzyme_N) 		4 HIS A   8
ASP A   9
TYR A  12
PRO A  39
 None
 1.47A 3fo7A-4q9dA:
undetectable		 3fo7A-4q9dA:
11.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4rfp ACIDIC PHOSPHOLIPASE
A2 5

(Trimeresurus
stejnegeri) 		PF00068
(Phospholip_A2_1) 		5 HIS A  47
ASP A  48
TYR A  51
PRO A  59
LYS A  60
 None
 0.86A 3fo7A-4rfpA:
20.0		 3fo7A-4rfpA:
53.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4wtb BASIC PHOSPHOLIPASE
A2 HOMOLOG
BOTHROPSTOXIN-1

(Bothrops
jararacussu) 		PF00068
(Phospholip_A2_1) 		4 HIS A  47
TYR A  51
PRO A  59
LYS A  60
 ZN  A 201 (-3.1A)
None
None
None
 0.53A 3fo7A-4wtbA:
21.4		 3fo7A-4wtbA:
55.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5all SOLUBLE EPOXIDE
HYDROLASE

(Homo sapiens) 		PF00561
(Abhydrolase_1)
PF13419
(HAD_2) 		4 HIS A 265
ASP A 292
TYR A 296
PRO A 462
 None
 1.23A 3fo7A-5allA:
undetectable		 3fo7A-5allA:
10.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gms ESTERASE

(uncultured
bacterium) 		PF07859
(Abhydrolase_3) 		4 HIS A  75
ASP A 106
TYR A 107
PRO A 118
 None
 1.37A 3fo7A-5gmsA:
undetectable		 3fo7A-5gmsA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5owc -

(-) 		no annotation 4 HIS A  46
ASP A  47
TYR A  50
PRO A  60
 AYZ  A 202 (-4.0A)
CA  A 201 ( 2.2A)
AYZ  A 202 ( 4.9A)
None
 0.52A 3fo7A-5owcA:
19.3		 3fo7A-5owcA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5tfv BASIC PHOSPHOLIPASE
A2 MYOTOXIN III

(Bothrops asper) 		PF00068
(Phospholip_A2_1) 		5 HIS A  48
ASP A  49
TYR A  52
PRO A  68
LYS A  69
 None
 0.89A 3fo7A-5tfvA:
20.9		 3fo7A-5tfvA:
68.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uro PREDICTED PROTEIN

(Trichoderma
reesei) 		PF00561
(Abhydrolase_1) 		4 HIS A  44
ASP A  48
TYR A  75
PRO A 248
 None
 1.43A 3fo7A-5uroA:
undetectable		 3fo7A-5uroA:
18.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5wzm GROUP IIE SECRETORY
PHOSPHOLIPASE A2

(Homo sapiens) 		no annotation 5 HIS A  46
ASP A  47
TYR A  50
PRO A  60
LYS A  61
 None
CA  A 210 (-2.2A)
None
CL  A 201 (-3.7A)
CL  A 201 (-4.0A)
 1.03A 3fo7A-5wzmA:
20.3		 3fo7A-5wzmA:
34.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xog DNA-DIRECTED RNA
POLYMERASE SUBUNIT
RNA POLYMERASE II
THIRD LARGEST
SUBUNIT B44, PART OF
CENTRAL CORE

(Komagataella
phaffii) 		PF00623
(RNA_pol_Rpb1_2)
PF01000
(RNA_pol_A_bac)
PF01193
(RNA_pol_L)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 ASP C 220
TYR C 221
PRO A 569
LYS A 570
 None
 1.43A 3fo7A-5xogC:
undetectable		 3fo7A-5xogC:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y1a -

(-) 		no annotation 4 HIS A 183
TYR A 181
PRO A  31
LYS A  34
 None
 1.42A 3fo7A-5y1aA:
undetectable		 3fo7A-5y1aA:
undetectable