SIMILAR PATTERNS OF AMINO ACIDS FOR 3FL9_F_TOPF200_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a9w | HEMOGLOBIN (BETACHAIN) (Homo sapiens) |
PF00042(Globin) | 5 | LEU E 114VAL E 134ALA E 23LEU E 106PHE E 71 | NoneNoneNoneHEM E 147 (-4.3A)HEM E 147 ( 4.7A) | 1.17A | 3fl9F-1a9wE:undetectable | 3fl9F-1a9wE:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cij | PROTEIN (HALOALKANEDEHALOGENASE) (Xanthobacterautotrophicus) |
PF00561(Abhydrolase_1) | 5 | ALA A 149LEU A 131ALA A 240ILE A 241PHE A 161 | None | 1.02A | 3fl9F-1cijA:undetectable | 3fl9F-1cijA:18.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dcn | DELTA 2 CRYSTALLIN (Anasplatyrhynchos) |
PF00206(Lyase_1)PF14698(ASL_C2) | 5 | LEU A 123VAL A 338ILE A 196LEU A 131PHE A 244 | None | 1.10A | 3fl9F-1dcnA:undetectable | 3fl9F-1dcnA:16.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1dr6 | DIHYDROFOLATEREDUCTASE (Gallus gallus) |
PF00186(DHFR_1) | 5 | ALA A 9ASN A 21LEU A 22GLU A 30LEU A 67 | HBI A 198 ( 3.6A)NoneNAP A 191 ( 4.7A)HBI A 198 (-3.0A)None | 0.97A | 3fl9F-1dr6A:20.4 | 3fl9F-1dr6A:32.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ef9 | METHYLMALONYL COADECARBOXYLASE (Escherichiacoli) |
PF00378(ECH_1) | 5 | ALA A 111VAL A 103ILE A 177LEU A 178PHE A 129 | None | 1.21A | 3fl9F-1ef9A:undetectable | 3fl9F-1ef9A:19.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g1a | DTDP-D-GLUCOSE4,6-DEHYDRATASE (Salmonellaenterica) |
PF16363(GDP_Man_Dehyd) | 5 | ALA A 106ALA A 57ILE A 31LEU A 4PHE A 69 | None | 1.17A | 3fl9F-1g1aA:undetectable | 3fl9F-1g1aA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gmi | PROTEIN KINASE C,EPSILON TYPE (Rattus rattus) |
PF00168(C2) | 5 | LEU A 44VAL A 73ILE A 129LEU A 131PHE A 102 | None | 1.03A | 3fl9F-1gmiA:undetectable | 3fl9F-1gmiA:20.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1moz | ADP-RIBOSYLATIONFACTOR-LIKE PROTEIN1 (Saccharomycescerevisiae) |
PF00025(Arf) | 5 | MET A 8ALA A 87ILE A 21LEU A 64PHE A 9 | None | 1.13A | 3fl9F-1mozA:undetectable | 3fl9F-1mozA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1moz | ADP-RIBOSYLATIONFACTOR-LIKE PROTEIN1 (Saccharomycescerevisiae) |
PF00025(Arf) | 6 | MET A 8LEU A 123ALA A 88ILE A 21LEU A 64PHE A 9 | None | 1.15A | 3fl9F-1mozA:undetectable | 3fl9F-1mozA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nrw | HYPOTHETICALPROTEIN, HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bacillussubtilis) |
PF08282(Hydrolase_3) | 5 | ASN A 14LEU A 13VAL A 39LEU A 27PHE A 52 | None | 1.19A | 3fl9F-1nrwA:undetectable | 3fl9F-1nrwA:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pzx | HYPOTHETICAL PROTEINAPC36103 (Geobacillusstearothermophilus) |
PF02645(DegV) | 5 | ALA A 67LEU A 26VAL A 101ALA A 24LEU A 114 | None | 1.08A | 3fl9F-1pzxA:undetectable | 3fl9F-1pzxA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pzx | HYPOTHETICAL PROTEINAPC36103 (Geobacillusstearothermophilus) |
PF02645(DegV) | 5 | ALA A 67VAL A 101ALA A 24ILE A 6LEU A 114 | None | 1.20A | 3fl9F-1pzxA:undetectable | 3fl9F-1pzxA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1us4 | PUTATIVE GLUR0LIGAND BINDING CORE (Thermusthermophilus) |
PF16868(NMT1_3) | 5 | ASN A 53VAL A 268ALA A 54ILE A 23LEU A 250 | None | 1.15A | 3fl9F-1us4A:undetectable | 3fl9F-1us4A:16.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wa5 | IMPORTIN ALPHASUBUNIT (Saccharomycescerevisiae) |
PF00514(Arm)PF01749(IBB)PF16186(Arm_3) | 5 | LEU B 437ALA B 501ILE B 504LEU B 456PHE B 509 | None | 1.23A | 3fl9F-1wa5B:undetectable | 3fl9F-1wa5B:14.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y9g | EXO-INULINASE (Aspergillusawamori) |
PF00251(Glyco_hydro_32N)PF08244(Glyco_hydro_32C) | 5 | VAL A 525ALA A 424ILE A 423LEU A 410PHE A 421 | None | 1.14A | 3fl9F-1y9gA:undetectable | 3fl9F-1y9gA:13.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yz6 | PROBABLE TRANSLATIONINITIATION FACTOR 2ALPHA SUBUNIT (Pyrococcusabyssi) |
PF00575(S1)PF07541(EIF_2_alpha) | 5 | ALA A 180LEU A 260ALA A 258ILE A 247PHE A 216 | None | 0.96A | 3fl9F-1yz6A:undetectable | 3fl9F-1yz6A:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yz7 | PROBABLE TRANSLATIONINITIATION FACTOR 2ALPHA SUBUNIT (Pyrococcusabyssi) |
PF07541(EIF_2_alpha) | 5 | ALA A 180LEU A 260ALA A 258ILE A 247PHE A 216 | None | 1.09A | 3fl9F-1yz7A:undetectable | 3fl9F-1yz7A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c7b | CARBOXYLESTERASE (unculturedarchaeon) |
PF07859(Abhydrolase_3) | 5 | ALA A 160VAL A 175ALA A 300ILE A 304LEU A 308 | None | 1.04A | 3fl9F-2c7bA:undetectable | 3fl9F-2c7bA:18.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cyb | TYROSYL-TRNASYNTHETASE (Archaeoglobusfulgidus) |
PF00579(tRNA-synt_1b) | 5 | LEU A 7GLU A 20VAL A 17ALA A 62LEU A 173 | None | 1.22A | 3fl9F-2cybA:undetectable | 3fl9F-2cybA:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d2x | 2-DEOXY-SCYLLO-INOSOSE SYNTHASE (Bacilluscirculans) |
PF01761(DHQ_synthase) | 5 | LEU A 351VAL A 228ILE A 190LEU A 191PHE A 242 | None | 1.11A | 3fl9F-2d2xA:undetectable | 3fl9F-2d2xA:18.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dc1 | L-ASPARTATEDEHYDROGENASE (Archaeoglobusfulgidus) |
PF01958(DUF108)PF03447(NAD_binding_3) | 5 | ASN A 206VAL A 177ALA A 111ILE A 112LEU A 167 | NoneNoneCIT A1585 ( 3.1A)NoneNone | 1.15A | 3fl9F-2dc1A:undetectable | 3fl9F-2dc1A:22.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ffh | PROTEIN (FFH) (Thermusaquaticus) |
PF00448(SRP54)PF02881(SRP54_N)PF02978(SRP_SPB) | 5 | LEU A 86VAL A 43ALA A 288ILE A 291LEU A 5 | None | 1.23A | 3fl9F-2ffhA:4.4 | 3fl9F-2ffhA:18.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g3n | ALPHA-GLUCOSIDASE (Sulfolobussolfataricus) |
PF01055(Glyco_hydro_31)PF13802(Gal_mutarotas_2) | 5 | ALA A 410LEU A 319ILE A 306LEU A 310PHE A 387 | None | 1.15A | 3fl9F-2g3nA:undetectable | 3fl9F-2g3nA:11.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2j3m | PROLYL-TRNASYNTHETASE (Enterococcusfaecalis) |
PF00587(tRNA-synt_2b)PF03129(HGTP_anticodon)PF04073(tRNA_edit) | 5 | MET A 1ALA A 519ILE A 522LEU A 45PHE A 471 | None | 1.03A | 3fl9F-2j3mA:undetectable | 3fl9F-2j3mA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jjf | L-LYSINE EPSILONAMINOTRANSFERASE (Mycobacteriumtuberculosis) |
PF00202(Aminotran_3) | 5 | ALA A 256LEU A 218ILE A 196LEU A 163PHE A 235 | None | 0.94A | 3fl9F-2jjfA:undetectable | 3fl9F-2jjfA:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2o7p | RIBOFLAVINBIOSYNTHESIS PROTEINRIBD (Escherichiacoli) |
PF00383(dCMP_cyt_deam_1)PF01872(RibD_C) | 5 | ALA A 189LEU A 288ALA A 254ILE A 232LEU A 304 | NoneNoneNoneNAP A 402 ( 4.8A)NAP A 402 (-4.0A) | 1.08A | 3fl9F-2o7pA:13.7 | 3fl9F-2o7pA:16.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2po4 | VIRION RNAPOLYMERASE (Escherichiavirus N4) |
no annotation | 5 | ALA A 913VAL A 890ALA A 321LEU A 859PHE A 831 | None | 1.09A | 3fl9F-2po4A:undetectable | 3fl9F-2po4A:10.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2qk8 | DIHYDROFOLATEREDUCTASE (Bacillusanthracis) |
PF00186(DHFR_1) | 9 | MET A 6ALA A 8LEU A 21GLU A 28VAL A 32ALA A 50ILE A 51LEU A 55PHE A 96 | MTX A 200 ( 4.1A)MTX A 200 ( 3.4A)MTX A 200 ( 4.5A)MTX A 200 ( 2.8A)MTX A 200 ( 4.7A)MTX A 200 ( 4.0A)MTX A 200 ( 4.2A)MTX A 200 ( 4.1A)MTX A 200 ( 3.9A) | 0.79A | 3fl9F-2qk8A:27.7 | 3fl9F-2qk8A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qm1 | GLUCOKINASE (Enterococcusfaecalis) |
PF00480(ROK) | 5 | ALA A 229VAL A 239ALA A 213ILE A 214PHE A 235 | None | 1.16A | 3fl9F-2qm1A:undetectable | 3fl9F-2qm1A:19.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rvj | EPITHELIAL SPLICINGREGULATORY PROTEIN 1 (Homo sapiens) |
PF00076(RRM_1) | 5 | ALA A 504VAL A 520ILE A 461LEU A 452PHE A 464 | None | 0.85A | 3fl9F-2rvjA:undetectable | 3fl9F-2rvjA:19.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vfk | AKAP18 DELTA (Homo sapiens) |
PF10469(AKAP7_NLS) | 5 | ALA A 204LEU A 94VAL A 160ILE A 96LEU A 262 | None | 1.07A | 3fl9F-2vfkA:undetectable | 3fl9F-2vfkA:23.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2w9s | DIHYDROFOLATEREDUCTASE TYPE 1FROM TN4003 (Staphylococcusaureus) |
PF00186(DHFR_1) | 5 | ALA A 7LEU A 20ILE A 50LEU A 54PHE A 92 | TOP A1160 ( 3.6A)TOP A1160 ( 4.2A)TOP A1160 (-4.4A)NoneTOP A1160 ( 3.9A) | 0.76A | 3fl9F-2w9sA:24.8 | 3fl9F-2w9sA:44.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsm | HYDROGENASEEXPRESSION/FORMATIONPROTEIN (HYPB) (Archaeoglobusfulgidus) |
PF02492(cobW) | 5 | ALA A 38GLU A 141VAL A 145ILE A 159PHE A 153 | None | 1.20A | 3fl9F-2wsmA:3.6 | 3fl9F-2wsmA:22.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x8u | SERINEPALMITOYLTRANSFERASE (Sphingomonaswittichii) |
PF00155(Aminotran_1_2) | 5 | ASN A 305LEU A 373ILE A 385LEU A 352PHE A 389 | None | 1.11A | 3fl9F-2x8uA:2.3 | 3fl9F-2x8uA:17.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xty | QNRB1 (Klebsiellapneumoniae) |
PF00805(Pentapeptide)PF13599(Pentapeptide_4) | 5 | ALA A 91ALA A 114ILE A 84LEU A 61PHE A 66 | None | 1.23A | 3fl9F-2xtyA:undetectable | 3fl9F-2xtyA:21.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aal | PROBABLEENDONUCLEASE 4 (Geobacilluskaustophilus) |
PF01261(AP_endonuc_2) | 5 | ALA A 70LEU A 107ALA A 104ILE A 102LEU A 49 | None | 0.97A | 3fl9F-3aalA:undetectable | 3fl9F-3aalA:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3aiz | DNA POLYMERASESLIDING CLAMP C (Sulfurisphaeratokodaii) |
PF00705(PCNA_N)PF02747(PCNA_C) | 5 | LEU C 178ALA C 132ILE C 217LEU C 227PHE C 156 | None | 1.02A | 3fl9F-3aizC:undetectable | 3fl9F-3aizC:19.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bq8 | SENSOR PROTEIN PHOQ (Escherichiacoli) |
PF08918(PhoQ_Sensor) | 5 | MET A 85ALA A 98LEU A 95VAL A 102ILE A 109 | None | 1.12A | 3fl9F-3bq8A:undetectable | 3fl9F-3bq8A:18.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eey | PUTATIVE RRNAMETHYLASE (Ruminiclostridiumthermocellum) |
PF06962(rRNA_methylase) | 5 | ALA A 36ASN A 60VAL A 74ALA A 57ILE A 58 | NoneNoneNoneSAM A 300 ( 4.3A)None | 1.17A | 3fl9F-3eeyA:2.7 | 3fl9F-3eeyA:22.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fah | ALDEHYDEOXIDOREDUCTASE (Desulfovibriogigas) |
PF00111(Fer2)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2) | 5 | ALA A 59VAL A 26ALA A 71ILE A 6LEU A 15 | None | 1.10A | 3fl9F-3fahA:undetectable | 3fl9F-3fahA:12.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3foa | TAIL SHEATH PROTEINGP18 (Escherichiavirus T4) |
PF04984(Phage_sheath_1)PF17481(Phage_sheath_1N) | 5 | LEU A 340ALA A 96ILE A 95LEU A 214PHE A 210 | None | 1.21A | 3fl9F-3foaA:undetectable | 3fl9F-3foaA:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gdz | ARGINYL-TRNASYNTHETASE (Klebsiellapneumoniae) |
PF03485(Arg_tRNA_synt_N) | 5 | ALA A 48ASN A 42ALA A 41ILE A 83LEU A 63 | NoneEDO A 107 ( 3.2A)NoneNoneNone | 1.08A | 3fl9F-3gdzA:undetectable | 3fl9F-3gdzA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gfo | COBALT IMPORTATP-BINDING PROTEINCBIO 1 (Clostridiumperfringens) |
PF00005(ABC_tran) | 5 | VAL A 8ALA A 36ILE A 37LEU A 48PHE A 52 | None | 1.23A | 3fl9F-3gfoA:undetectable | 3fl9F-3gfoA:20.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3i8a | DIHYDROFOLATEREDUCTASE (Staphylococcusaureus) |
PF00186(DHFR_1) | 6 | ALA X 7LEU X 20VAL X 31ILE X 50LEU X 54PHE X 92 | N22 X 219 ( 3.6A)N22 X 219 ( 4.6A)NoneN22 X 219 (-4.6A)NoneN22 X 219 ( 3.7A) | 0.67A | 3fl9F-3i8aX:25.0 | 3fl9F-3i8aX:46.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j2n | TAIL SHEATH PROTEINGP18 (Escherichiavirus T4) |
PF04984(Phage_sheath_1)PF17481(Phage_sheath_1N)PF17482(Phage_sheath_1C) | 5 | LEU U 340ALA U 96ILE U 95LEU U 214PHE U 210 | None | 1.21A | 3fl9F-3j2nU:undetectable | 3fl9F-3j2nU:13.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9d | OUTER CAPSID PROTEINVP2 (Bluetonguevirus) |
PF00898(Orbi_VP2) | 5 | ALA A 730ASN A 807LEU A 806ALA A 809ILE A 813 | None | 1.04A | 3fl9F-3j9dA:undetectable | 3fl9F-3j9dA:11.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jby | V(D)JRECOMBINATION-ACTIVATING PROTEIN 1 (Danio rerio) |
PF12940(RAG1) | 5 | LEU A 597VAL A 713ILE A 649LEU A 586PHE A 720 | None | 1.14A | 3fl9F-3jbyA:undetectable | 3fl9F-3jbyA:10.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ke3 | PUTATIVESERINE-PYRUVATEAMINOTRANSFERASE (Psychrobacterarcticus) |
PF00266(Aminotran_5) | 5 | ALA A 158GLU A 154ALA A 140ILE A 172LEU A 182 | None | 1.19A | 3fl9F-3ke3A:undetectable | 3fl9F-3ke3A:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lwt | PHOSPHOINOSITIDEPHOSPHATASE SAC1 (Saccharomycescerevisiae) |
PF02383(Syja_N) | 5 | ALA X 56VAL X 90ALA X 70ILE X 71LEU X 119 | None | 1.14A | 3fl9F-3lwtX:undetectable | 3fl9F-3lwtX:17.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nap | CAPSID PROTEIN (Triatoma virus) |
PF00073(Rhv) | 5 | ALA B 113LEU B 110VAL B 236LEU B 151PHE B 106 | None | 1.01A | 3fl9F-3napB:undetectable | 3fl9F-3napB:17.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nbh | RECQ-MEDIATED GENOMEINSTABILITY PROTEIN1 (Homo sapiens) |
PF16099(RMI1_C) | 5 | ALA A 603VAL A 534ALA A 607LEU A 588PHE A 545 | None | 1.17A | 3fl9F-3nbhA:undetectable | 3fl9F-3nbhA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nk4 | ZONA PELLUCIDA 3 (Gallus gallus) |
PF00100(Zona_pellucida) | 5 | VAL A 226ALA A 231ILE A 293LEU A 186PHE A 276 | None | 1.15A | 3fl9F-3nk4A:undetectable | 3fl9F-3nk4A:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qkx | UNCHARACTERIZEDHTH-TYPETRANSCRIPTIONALREGULATOR HI_0893 (Haemophilusinfluenzae) |
PF00440(TetR_N) | 5 | MET A 65ALA A 155ILE A 156LEU A 105PHE A 66 | None | 1.11A | 3fl9F-3qkxA:undetectable | 3fl9F-3qkxA:15.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r1o | ODORANT BINDINGPROTEIN, ANTENNAL (Anophelesgambiae) |
PF01395(PBP_GOBP) | 5 | LEU A 124VAL A 107ILE A 57LEU A 72PHE A 54 | PLM A 128 (-4.9A)PLM A 128 ( 4.7A)PLM A 128 ( 4.5A)NonePLM A 128 ( 4.9A) | 1.18A | 3fl9F-3r1oA:undetectable | 3fl9F-3r1oA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r79 | UNCHARACTERIZEDPROTEIN (Agrobacteriumfabrum) |
PF01168(Ala_racemase_N) | 5 | ALA A 92LEU A 84ILE A 102LEU A 157PHE A 124 | None | 1.10A | 3fl9F-3r79A:undetectable | 3fl9F-3r79A:23.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sun | DNA POLYMERASE (Escherichiavirus RB69) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | LEU A 533VAL A 516ALA A 502ILE A 499PHE A 522 | None | 1.09A | 3fl9F-3sunA:undetectable | 3fl9F-3sunA:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tfz | CYCLASE (Streptomycessp. R1128) |
PF10604(Polyketide_cyc2) | 5 | ALA A 137ASN A 60ALA A 83ILE A 85LEU A 126 | None | 1.23A | 3fl9F-3tfzA:undetectable | 3fl9F-3tfzA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3thu | MANDELATE RACEMASE /MUCONATE LACTONIZINGENZYME FAMILYPROTEIN (Sphingomonassp. SKA58) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 35LEU A 48ALA A 7ILE A 23LEU A 94 | None | 1.16A | 3fl9F-3thuA:undetectable | 3fl9F-3thuA:17.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v4b | STARVATION SENSINGPROTEIN RSPA (Cellvibriojaponicus) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 34LEU A 47ALA A 6ILE A 22LEU A 93 | None | 1.17A | 3fl9F-3v4bA:undetectable | 3fl9F-3v4bA:16.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vcn | MANNONATEDEHYDRATASE (Caulobactervibrioides) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 35LEU A 48ALA A 7ILE A 23LEU A 94 | None | 1.23A | 3fl9F-3vcnA:undetectable | 3fl9F-3vcnA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bxm | ERPC (Borreliellaburgdorferi) |
PF02471(OspE) | 5 | LEU A 75VAL A 44ILE A 84LEU A 157PHE A 20 | None | 1.20A | 3fl9F-4bxmA:undetectable | 3fl9F-4bxmA:23.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7v | TRANSKETOLASE (Lactobacillussalivarius) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 5 | ALA A 173ALA A 154ILE A 156LEU A 161PHE A 208 | None | 1.23A | 3fl9F-4c7vA:undetectable | 3fl9F-4c7vA:14.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d5g | CYCLOHEXANE-1,2-DIONE HYDROLASE (Azoarcus sp.BH72) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ALA A 272ASN A 266ALA A 257ILE A 287LEU A 282 | None | 1.18A | 3fl9F-4d5gA:2.6 | 3fl9F-4d5gA:14.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dzi | PUTATIVE TIM-BARRELMETAL-DEPENDENTHYDROLASE (Mycobacteriumavium) |
PF04909(Amidohydro_2) | 5 | LEU A 120VAL A 289ALA A 164ILE A 163LEU A 392 | None | 1.19A | 3fl9F-4dziA:undetectable | 3fl9F-4dziA:16.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fi4 | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Caulobacter sp.K31) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ALA A 35LEU A 48ALA A 7ILE A 23LEU A 94 | None | 1.21A | 3fl9F-4fi4A:undetectable | 3fl9F-4fi4A:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g1g | MATRIX PROTEIN (Avianavulavirus 1) |
PF00661(Matrix) | 5 | ALA A 307ASN A 234ALA A 233ILE A 210LEU A 270 | None | 0.96A | 3fl9F-4g1gA:undetectable | 3fl9F-4g1gA:15.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k7c | AMINOPEPTIDASE C (Lactobacillusrhamnosus) |
PF03051(Peptidase_C1_2) | 5 | ALA A 399LEU A 368ALA A 305ILE A 306LEU A 373 | None | 1.16A | 3fl9F-4k7cA:undetectable | 3fl9F-4k7cA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kk7 | ESX-1 SECRETIONSYSTEM PROTEIN ECCB1 (Mycobacteriumtuberculosis) |
PF05108(T7SS_ESX1_EccB) | 5 | ALA A 296LEU A 244VAL A 289ILE A 247LEU A 282 | None | 1.21A | 3fl9F-4kk7A:undetectable | 3fl9F-4kk7A:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lec | PROTEIN-LYSINEMETHYLTRANSFERASEMETTL21A (Homo sapiens) |
PF10294(Methyltransf_16) | 5 | ALA A 83LEU A 141VAL A 62ALA A 172ILE A 206 | None | 1.13A | 3fl9F-4lecA:undetectable | 3fl9F-4lecA:22.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nia | COAT PROTEIN (Tobaccovirtovirus 1) |
no annotation | 5 | VAL A 55ALA A 40ILE A 41LEU A 60PHE A 43 | None A d 167 ( 3.5A)NoneNoneNone | 1.19A | 3fl9F-4niaA:undetectable | 3fl9F-4niaA:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ol9 | PUTATIVE2-DEHYDROPANTOATE2-REDUCTASE (Mycobacteriumtuberculosis) |
PF02558(ApbA)PF08546(ApbA_C) | 5 | ALA A 162LEU A 142ALA A 96ILE A 70LEU A 7 | None | 1.04A | 3fl9F-4ol9A:undetectable | 3fl9F-4ol9A:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4paf | TRAP DICARBOXYLATETRANSPORTER, DCTPSUBUNIT, PUTATIVE (Ruegeriapomeroyi) |
PF03480(DctP) | 5 | MET A 102ALA A 323ILE A 120LEU A 121PHE A 105 | None | 1.15A | 3fl9F-4pafA:undetectable | 3fl9F-4pafA:17.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qiw | DNA-DIRECTED RNAPOLYMERASE SUBUNIT D (Thermococcuskodakarensis) |
PF01000(RNA_pol_A_bac)PF01193(RNA_pol_L) | 5 | ALA D 93LEU D 123ILE D 59LEU D 63PHE D 131 | None | 0.97A | 3fl9F-4qiwD:undetectable | 3fl9F-4qiwD:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qpn | PROTEIN-LYSINEMETHYLTRANSFERASEMETTL21B (Homo sapiens) |
PF10294(Methyltransf_16) | 5 | ALA A 93LEU A 148VAL A 72ALA A 179ILE A 215 | None | 1.06A | 3fl9F-4qpnA:2.1 | 3fl9F-4qpnA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ux8 | PROTO-ONCOGENETYROSINE-PROTEINKINASE RECEPTOR RET (Homo sapiens) |
PF00028(Cadherin) | 5 | ALA A 294LEU A 296VAL A 374LEU A 319PHE A 329 | None | 1.20A | 3fl9F-4ux8A:undetectable | 3fl9F-4ux8A:11.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wen | K88 FIMBRIAL PROTEINAC (Escherichiacoli) |
PF02432(Fimbrial_K88) | 5 | VAL A 54ALA A 253ILE A 277LEU A 33PHE A 36 | None | 1.16A | 3fl9F-4wenA:undetectable | 3fl9F-4wenA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zij | THIOL:DISULFIDEINTERCHANGE PROTEINDSBA (Escherichiacoli) |
PF01323(DSBA) | 5 | ALA A 125ALA A 105ILE A 108LEU A 92PHE A 112 | None | 1.15A | 3fl9F-4zijA:undetectable | 3fl9F-4zijA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ah4 | DNA POLYMERASE IIISUBUNIT BETA (Mycolicibacteriumsmegmatis) |
PF00712(DNA_pol3_beta)PF02767(DNA_pol3_beta_2)PF02768(DNA_pol3_beta_3) | 5 | ALA A 271LEU A 304ALA A 281ILE A 282LEU A 338 | None | 1.17A | 3fl9F-5ah4A:undetectable | 3fl9F-5ah4A:15.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b4x | LOW DENSITYLIPOPROTEINRECEPTOR-RELATEDPROTEIN 8,APOLIPOPROTEIN ERECEPTOR, ISOFORMCRA_E (Homo sapiens) |
PF00057(Ldl_recept_a)PF00058(Ldl_recept_b)PF07645(EGF_CA)PF14670(FXa_inhibition) | 5 | ALA B 433VAL B 449ALA B 414ILE B 459LEU B 468 | None | 1.16A | 3fl9F-5b4xB:undetectable | 3fl9F-5b4xB:13.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5czc | MALONYL-COA-[ACYL-CARRIER-PROTEIN]TRANSACYLASE (Streptomyceshalstedii) |
no annotation | 5 | ALA A 113VAL A 85ALA A 129ILE A 78PHE A 121 | None | 1.22A | 3fl9F-5czcA:undetectable | 3fl9F-5czcA:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5d8g | TRYPTOPHANASE (Escherichiacoli) |
PF01212(Beta_elim_lyase) | 5 | ALA A 208ASN A 133GLU A 242ALA A 193ILE A 195 | None | 1.10A | 3fl9F-5d8gA:undetectable | 3fl9F-5d8gA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e43 | BETA-LACTAMASE (Streptosporangiumroseum) |
PF13354(Beta-lactamase2) | 5 | ALA A 79VAL A 194ALA A 127ILE A 128LEU A 212 | None | 0.78A | 3fl9F-5e43A:undetectable | 3fl9F-5e43A:17.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kuf | GLUTAMATE RECEPTORIONOTROPIC, KAINATE2 (Rattusnorvegicus) |
PF00060(Lig_chan)PF01094(ANF_receptor)PF10613(Lig_chan-Glu_bd) | 5 | ALA A 74VAL A 303ALA A 29ILE A 33LEU A 40 | None | 1.20A | 3fl9F-5kufA:2.7 | 3fl9F-5kufA:12.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mms | CYSTATHIONINEBETA-SYNTHASE (Homo sapiens) |
PF00291(PALP) | 5 | ALA A 361LEU A 101VAL A 372ILE A 95LEU A 338 | None | 1.23A | 3fl9F-5mmsA:2.9 | 3fl9F-5mmsA:16.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mqp | GLYCOSIDE HYDROLASEBT_1002 (Bacteroidesthetaiotaomicron) |
no annotation | 5 | ALA A 177LEU A 251VAL A 173ALA A 193ILE A 208 | None | 1.00A | 3fl9F-5mqpA:undetectable | 3fl9F-5mqpA:13.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n5n | TUBULIN BETA CHAIN (Homo sapiens) |
no annotation | 5 | ALA B 421ASN B 186LEU B 189LEU B 405PHE B 399 | None | 1.12A | 3fl9F-5n5nB:undetectable | 3fl9F-5n5nB:15.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nag | KYNURENINE3-MONOOXYGENASE (Pseudomonasfluorescens) |
PF01494(FAD_binding_3) | 5 | ALA A 366ASN A 325ALA A 58ILE A 106LEU A 213 | NoneFAD A 501 (-3.9A)NoneNone8R5 A 502 ( 4.6A) | 1.05A | 3fl9F-5nagA:undetectable | 3fl9F-5nagA:15.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5thz | CURJ (Mooreaproducens) |
no annotation | 5 | ALA B 69LEU B 87VAL B 75ILE B 47LEU B 142 | None | 1.17A | 3fl9F-5thzB:undetectable | 3fl9F-5thzB:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uj5 | ADRENODOXIN (Encephalitozooncuniculi) |
PF00111(Fer2) | 5 | ALA A 111LEU A 67VAL A 39LEU A 50PHE A 22 | None | 1.07A | 3fl9F-5uj5A:undetectable | 3fl9F-5uj5A:24.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uz9 | CRISPR-ASSOCIATEDPROTEIN CSY3 (Pseudomonasaeruginosa) |
PF09615(Cas_Csy3) | 5 | ALA C 234LEU C 167ALA C 174ILE C 238LEU C 103 | None | 1.14A | 3fl9F-5uz9C:undetectable | 3fl9F-5uz9C:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vqi | IMPORTIN SUBUNITALPHA (Neurosporacrassa) |
no annotation | 5 | LEU B 431ALA B 498ILE B 501LEU B 450PHE B 506 | None | 1.23A | 3fl9F-5vqiB:undetectable | 3fl9F-5vqiB:14.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w3j | TUBULIN BETA CHAIN (Saccharomycescerevisiae) |
PF00091(Tubulin)PF03953(Tubulin_C) | 5 | ALA B 411ASN B 184LEU B 187LEU B 395PHE B 389 | None | 1.07A | 3fl9F-5w3jB:undetectable | 3fl9F-5w3jB:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5whs | CATALASE-PEROXIDASE (Neurosporacrassa) |
no annotation | 5 | LEU A 480VAL A 531ALA A 484ILE A 550LEU A 546 | None | 1.00A | 3fl9F-5whsA:undetectable | 3fl9F-5whsA:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wtn | REPLICATIONINITIATION ANDMEMBRANE ATTACHMENTPROTEIN (Geobacillusstearothermophilus) |
no annotation | 5 | ALA A 232LEU A 266VAL A 225LEU A 215PHE A 211 | None | 1.17A | 3fl9F-5wtnA:undetectable | 3fl9F-5wtnA:20.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xex | POLYRIBONUCLEOTIDENUCLEOTIDYLTRANSFERASE (Staphylococcusaureus) |
no annotation | 5 | MET A 511LEU A 177ALA A 193ILE A 506LEU A 527 | None | 1.18A | 3fl9F-5xexA:undetectable | 3fl9F-5xexA:14.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2v | RUBISCO OPERONTRANSCRIPTIONALREGULATOR (Synechocystissp. PCC 6803) |
no annotation | 5 | ALA A 204VAL A 240ILE A 184LEU A 187PHE A 209 | None | 1.09A | 3fl9F-5y2vA:undetectable | 3fl9F-5y2vA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y2w | RUBISCO OPERONTRANSCRIPTIONALREGULATOR (Synechocystissp. PCC 6803) |
no annotation | 5 | ALA A 204VAL A 240ILE A 184LEU A 187PHE A 209 | None | 1.14A | 3fl9F-5y2wA:undetectable | 3fl9F-5y2wA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z9s | GLYCOSYL HYDROLASEFAMILY 3 PROTEIN (Bifidobacteriumlongum) |
no annotation | 5 | ALA A 464ASN A 504VAL A 515ALA A 505ILE A 511 | None | 1.15A | 3fl9F-5z9sA:undetectable | 3fl9F-5z9sA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bii | GLYOXYLATE REDUCTASE (Pyrococcusyayanosii) |
no annotation | 5 | ASN A 282VAL A 245ALA A 261ILE A 259LEU A 227 | None | 1.21A | 3fl9F-6biiA:undetectable | 3fl9F-6biiA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6e4e | - (-) |
no annotation | 6 | ALA A 7LEU A 20VAL A 31ILE A 50LEU A 54PHE A 92 | MMV A 202 ( 3.5A)MMV A 202 (-4.3A)MMV A 202 (-4.9A)MMV A 202 ( 4.9A)NoneMMV A 202 ( 3.5A) | 0.63A | 3fl9F-6e4eA:25.1 | 3fl9F-6e4eA:undetectable |