SIMILAR PATTERNS OF AMINO ACIDS FOR 3FAL_C_REAC501
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dab | P.69 PERTACTIN (Bordetellapertussis) |
PF03212(Pertactin) | 5 | ALA A 387ALA A 357LEU A 383ALA A 384ILE A 310 | None | 1.02A | 3falC-1dabA:undetectable | 3falC-1dabA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dqu | ISOCITRATE LYASE (Aspergillusnidulans) |
PF00463(ICL) | 5 | ILE A 166ALA A 192ALA A 191LEU A 59ALA A 56 | None | 0.94A | 3falC-1dquA:undetectable | 3falC-1dquA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fc4 | 2-AMINO-3-KETOBUTYRATE CONENZYME ALIGASE (Escherichiacoli) |
PF00155(Aminotran_1_2) | 5 | ILE A 238ALA A 255ALA A 256LEU A 100ALA A 97 | None | 0.89A | 3falC-1fc4A:undetectable | 3falC-1fc4A:22.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fs5 | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Escherichiacoli) |
PF01182(Glucosamine_iso) | 5 | ILE A 20ALA A 17ALA A 16LEU A 52ALA A 51 | None | 1.03A | 3falC-1fs5A:undetectable | 3falC-1fs5A:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kbl | PYRUVATE PHOSPHATEDIKINASE ([Clostridium]symbiosum) |
PF00391(PEP-utilizers)PF01326(PPDK_N)PF02896(PEP-utilizers_C) | 5 | ILE A 368ALA A 370LEU A 864ALA A 865ILE A 359 | None | 1.00A | 3falC-1kblA:undetectable | 3falC-1kblA:15.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1m4y | ATP-DEPENDENTPROTEASE HSLV (Thermotogamaritima) |
PF00227(Proteasome) | 5 | ILE A 122ALA A 47LEU A 94ALA A 93ILE A 103 | None | 1.03A | 3falC-1m4yA:undetectable | 3falC-1m4yA:21.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n60 | CARBON MONOXIDEDEHYDROGENASE SMALLCHAIN (Oligotrophacarboxidovorans) |
PF00111(Fer2)PF01799(Fer2_2) | 5 | ILE A 149ALA A 152ALA A 153LEU A 90ALA A 89 | None | 0.96A | 3falC-1n60A:undetectable | 3falC-1n60A:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nmo | HYPOTHETICAL PROTEINYBGI (Escherichiacoli) |
PF01784(NIF3) | 5 | ILE A 179ALA A 182ALA A 183ALA A 169ILE A 200 | None | 0.99A | 3falC-1nmoA:undetectable | 3falC-1nmoA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1prz | RIBOSOMAL LARGESUBUNITPSEUDOURIDINESYNTHASE D (Escherichiacoli) |
PF00849(PseudoU_synth_2) | 5 | ILE A 236ALA A 173LEU A 279ALA A 278ILE A 189 | None | 1.02A | 3falC-1przA:undetectable | 3falC-1przA:21.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uhl | RETINOIC ACIDRECEPTOR RXR-BETA (Homo sapiens) |
PF00104(Hormone_recep) | 10 | ILE A 339ALA A 342ALA A 343GLN A 346PHE A 384ARG A 387LEU A 397ALA A 398ILE A 416CYH A 503 | MEI A1001 (-3.8A)MEI A1001 (-3.1A)MEI A1001 (-3.3A)NoneMEI A1001 (-4.5A)MEI A1001 (-3.6A)MEI A1001 ( 4.4A)MEI A1001 (-3.4A)NoneMEI A1001 (-4.0A) | 0.66A | 3falC-1uhlA:29.6 | 3falC-1uhlA:88.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ukw | ACYL-COADEHYDROGENASE (Thermusthermophilus) |
PF00441(Acyl-CoA_dh_1)PF02770(Acyl-CoA_dh_M)PF02771(Acyl-CoA_dh_N) | 5 | ILE A 117ALA A 120LEU A 150ALA A 151ILE A 55 | None | 0.93A | 3falC-1ukwA:undetectable | 3falC-1ukwA:21.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1umf | CHORISMATE SYNTHASE (Helicobacterpylori) |
PF01264(Chorismate_synt) | 5 | ALA A 139ALA A 137LEU A 341ALA A 340ILE A 83 | None | 1.05A | 3falC-1umfA:undetectable | 3falC-1umfA:20.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wve | 4-CRESOLDEHYDROGENASE[HYDROXYLATING]FLAVOPROTEIN SUBUNIT (Pseudomonasputida) |
PF01565(FAD_binding_4)PF02913(FAD-oxidase_C) | 5 | GLN A 23PHE A 25LEU A 28ALA A 27ILE A 507 | None | 1.03A | 3falC-1wveA:undetectable | 3falC-1wveA:17.78 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xiu | RXR-LIKE PROTEIN (Biomphalariaglabrata) |
PF00104(Hormone_recep) | 10 | ILE A 242ALA A 245ALA A 246GLN A 249PHE A 287ARG A 290LEU A 300ALA A 301ILE A 319CYH A 406 | 9CR A 201 ( 4.4A)9CR A 201 (-3.6A)9CR A 201 (-3.6A)9CR A 201 (-4.1A)9CR A 201 (-4.7A)9CR A 201 (-2.8A)9CR A 201 (-4.4A)9CR A 201 (-3.4A)None9CR A 201 (-3.6A) | 0.36A | 3falC-1xiuA:30.1 | 3falC-1xiuA:81.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xls | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 10 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345CYH A 432 | 9CR A 801 (-3.9A)9CR A 801 (-3.6A)9CR A 801 (-3.5A)9CR A 801 (-4.7A)9CR A 801 (-4.3A)9CR A 801 (-2.6A)9CR A 801 (-4.1A)9CR A 801 (-3.3A)9CR A 801 ( 4.5A)9CR A 801 ( 3.7A) | 0.32A | 3falC-1xlsA:29.4 | 3falC-1xlsA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yfm | FUMARASE (Saccharomycescerevisiae) |
PF00206(Lyase_1)PF10415(FumaraseC_C) | 5 | ILE A 391ALA A 176ALA A 177GLN A 180LEU A 70 | None | 1.05A | 3falC-1yfmA:undetectable | 3falC-1yfmA:20.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1z5x | ULTRASPIRACLEPROTEIN (USP) AHOMOLOGUE OF RXR (Bemisia tabaci) |
PF00104(Hormone_recep) | 5 | ILE U 303ALA U 306ALA U 307LEU U 365ALA U 362 | None | 0.85A | 3falC-1z5xU:22.0 | 3falC-1z5xU:63.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zk7 | MERCURIC REDUCTASE (Pseudomonasaeruginosa) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 452ALA A 451GLN A 453LEU A 434ALA A 435 | NoneNoneGOL A3003 ( 3.8A)NoneNone | 0.91A | 3falC-1zk7A:undetectable | 3falC-1zk7A:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g39 | ACETYL-COA HYDROLASE (Pseudomonasaeruginosa) |
PF02550(AcetylCoA_hydro)PF13336(AcetylCoA_hyd_C) | 5 | ILE A 25ALA A 22ALA A 21LEU A 49ALA A 48 | None | 1.06A | 3falC-2g39A:undetectable | 3falC-2g39A:19.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gl8 | RETINOIC ACIDRECEPTOR RXR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | PHE A 92ARG A 95LEU A 105ALA A 106ILE A 124CYH A 211 | None | 0.84A | 3falC-2gl8A:28.1 | 3falC-2gl8A:85.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ist | RIBOSOMAL LARGESUBUNITPSEUDOURIDINESYNTHASE D (Escherichiacoli) |
PF00849(PseudoU_synth_2)PF01479(S4) | 5 | ILE A 236ALA A 173LEU A 279ALA A 278ILE A 189 | None | 1.02A | 3falC-2istA:undetectable | 3falC-2istA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ji9 | OXALYL-COADECARBOXYLASE (Oxalobacterformigenes) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 5 | ILE A 210ALA A 207ALA A 206LEU A 337ALA A 336 | None | 1.03A | 3falC-2ji9A:undetectable | 3falC-2ji9A:18.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2nxx | ULTRASPIRACLE (USP,NR2B4) (Triboliumcastaneum) |
PF00104(Hormone_recep) | 5 | PHE A 259ARG A 262LEU A 272ALA A 273CYH A 378 | None | 0.74A | 3falC-2nxxA:24.6 | 3falC-2nxxA:63.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p6w | PUTATIVEGLYCOSYLTRANSFERASE(MANNOSYLTRANSFERASE) INVOLVED INGLYCOSYLATING THEPBCV-1 MAJOR CAPSIDPROTEIN (ParameciumbursariaChlorella virus1) |
PF05637(Glyco_transf_34) | 5 | ILE A 61ALA A 64ALA A 65LEU A 9ILE A 132 | None | 0.84A | 3falC-2p6wA:undetectable | 3falC-2p6wA:23.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q60 | RETINOID X RECEPTOR (Polyandrocarpamisakiensis) |
PF00104(Hormone_recep) | 5 | PHE A 188ARG A 191ALA A 202ILE A 220CYH A 307 | None | 0.65A | 3falC-2q60A:27.6 | 3falC-2q60A:72.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q8w | POKEWEED ANTIVIRALPROTEIN (Phytolaccaacinosa) |
PF00161(RIP) | 5 | ILE A 214ALA A 217ARG A 240LEU A 222ALA A 221 | None | 1.01A | 3falC-2q8wA:undetectable | 3falC-2q8wA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qb0 | TELSAM DOMAIN -LYSOZYME CHIMERA (Escherichiavirus T4) |
PF00959(Phage_lysozyme)PF02198(SAM_PNT) | 5 | ALA B 222PHE B 246LEU B 226ALA B 223ILE B 171 | None | 1.02A | 3falC-2qb0B:undetectable | 3falC-2qb0B:24.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qr4 | PEPTIDASE M3B,OLIGOENDOPEPTIDASE F (Enterococcusfaecium) |
PF01432(Peptidase_M3)PF08439(Peptidase_M3_N) | 5 | ILE A 62GLN A 57PHE A 58LEU A 59ILE A 145 | None | 1.02A | 3falC-2qr4A:undetectable | 3falC-2qr4A:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xax | RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1SUBUNIT ALPHA (Escherichiacoli) |
PF00317(Ribonuc_red_lgN)PF02867(Ribonuc_red_lgC)PF03477(ATP-cone) | 5 | ILE A 62ALA A 66ALA A 65LEU A 84ALA A 81 | None | 1.02A | 3falC-2xaxA:undetectable | 3falC-2xaxA:17.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3afg | SUBTILISIN-LIKESERINE PROTEASE (Thermococcuskodakarensis) |
PF00082(Peptidase_S8)PF04151(PPC) | 5 | ILE A 368ALA A 415ALA A 416LEU A 388ALA A 387 | None | 0.98A | 3falC-3afgA:undetectable | 3falC-3afgA:17.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3al0 | ASPARTYL/GLUTAMYL-TRNA(ASN/GLN)AMIDOTRANSFERASESUBUNIT B (Thermotogamaritima) |
PF02637(GatB_Yqey)PF02934(GatB_N) | 5 | ILE B 11GLN B 14LEU B 196ALA B 195ILE B 119 | None | 0.98A | 3falC-3al0B:undetectable | 3falC-3al0B:18.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ce6 | ADENOSYLHOMOCYSTEINASE (Mycobacteriumtuberculosis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 5 | ALA A 104ALA A 102PHE A 31LEU A 28ALA A 29 | None | 1.05A | 3falC-3ce6A:undetectable | 3falC-3ce6A:19.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8u | PURR TRANSCRIPTIONALREGULATOR (Vibrioparahaemolyticus) |
PF13377(Peripla_BP_3) | 5 | ALA A 311ALA A 310LEU A 96ALA A 95ILE A 76 | None | 0.86A | 3falC-3d8uA:undetectable | 3falC-3d8uA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d8u | PURR TRANSCRIPTIONALREGULATOR (Vibrioparahaemolyticus) |
PF13377(Peripla_BP_3) | 5 | ALA A 311ALA A 310LEU A 96ALA A 95ILE A 77 | None | 1.04A | 3falC-3d8uA:undetectable | 3falC-3d8uA:20.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dme | CONSERVED EXPORTEDPROTEIN (Bordetellapertussis) |
PF01266(DAO) | 5 | ILE A 10ALA A 205ALA A 204LEU A 212ALA A 209 | FAD A 500 (-4.5A)FAD A 500 (-3.6A)NoneFAD A 500 ( 4.3A)None | 0.94A | 3falC-3dmeA:undetectable | 3falC-3dmeA:21.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dzu | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 10 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345CYH A 432 | 9CR A7223 (-3.9A)9CR A7223 (-3.5A)9CR A7223 (-4.2A)9CR A7223 (-4.6A)9CR A7223 (-4.5A)9CR A7223 (-3.7A)9CR A7223 (-3.8A)9CR A7223 ( 4.7A)9CR A7223 ( 4.9A)9CR A7223 (-3.8A) | 0.79A | 3falC-3dzuA:29.8 | 3falC-3dzuA:51.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h5k | RIBOSOME-INACTIVATING PROTEINPD-L1/PD-L2 (Phytolaccadioica) |
PF00161(RIP) | 5 | ILE A 214ALA A 217ARG A 240LEU A 222ALA A 221 | None | 0.99A | 3falC-3h5kA:undetectable | 3falC-3h5kA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7a | SHORT CHAINDEHYDROGENASE (Rhodopseudomonaspalustris) |
PF00106(adh_short) | 5 | ILE A 21ALA A 22ALA A 19ALA A 34ILE A 183 | ILE A 21 ( 0.6A)ALA A 22 ( 0.0A)ALA A 19 ( 0.0A)ALA A 34 ( 0.0A)ILE A 183 ( 0.7A) | 1.03A | 3falC-3h7aA:undetectable | 3falC-3h7aA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hve | GIGAXONIN (Homo sapiens) |
PF00651(BTB)PF07707(BACK) | 5 | ILE A 47ALA A 50ALA A 51LEU B 20ALA B 19 | None | 0.59A | 3falC-3hveA:undetectable | 3falC-3hveA:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hve | GIGAXONIN (Homo sapiens) |
PF00651(BTB)PF07707(BACK) | 5 | ILE B 47ALA B 50ALA B 51LEU A 20ALA A 19 | None | 0.66A | 3falC-3hveB:undetectable | 3falC-3hveB:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ic5 | PUTATIVESACCHAROPINEDEHYDROGENASE (Ruegeriapomeroyi) |
PF03435(Sacchrp_dh_NADP) | 5 | ILE A 82ALA A 85ALA A 86LEU A 60ALA A 61 | None | 0.78A | 3falC-3ic5A:undetectable | 3falC-3ic5A:21.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ipc | ABC TRANSPORTER,SUBSTRATE BINDINGPROTEIN (AMINO ACID) (Agrobacteriumfabrum) |
PF13458(Peripla_BP_6) | 5 | ILE A 286ALA A 289ALA A 290LEU A 305ALA A 304 | None | 0.73A | 3falC-3ipcA:undetectable | 3falC-3ipcA:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jbz | SERINE/THREONINE-PROTEIN KINASE MTOR (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08771(FRB_dom) | 5 | ILE A1994ALA A1991ALA A1990LEU A1976ALA A1979 | None | 1.05A | 3falC-3jbzA:undetectable | 3falC-3jbzA:12.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lqy | PUTATIVEISOCHORISMATASEHYDROLASE (Oleispiraantarctica) |
PF00857(Isochorismatase) | 5 | ALA A 146ALA A 35GLN A 38ALA A 182ILE A 77 | None | 1.04A | 3falC-3lqyA:undetectable | 3falC-3lqyA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3msu | CITRATE SYNTHASE (Francisellatularensis) |
PF00285(Citrate_synt) | 5 | ALA A 175ALA A 176LEU A 388ALA A 384ILE A 218 | None | 0.96A | 3falC-3msuA:undetectable | 3falC-3msuA:21.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o0m | HIT FAMILY PROTEIN (Mycolicibacteriumsmegmatis) |
PF01230(HIT) | 5 | ILE A 67ALA A 70ALA A 71LEU A 136ALA A 135 | None | 0.56A | 3falC-3o0mA:undetectable | 3falC-3o0mA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oks | 4-AMINOBUTYRATETRANSAMINASE (Mycolicibacteriumsmegmatis) |
PF00202(Aminotran_3) | 5 | ILE A 327ALA A 331ALA A 330LEU A 298ALA A 295 | None | 1.00A | 3falC-3oksA:undetectable | 3falC-3oksA:20.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qr8 | BASEPLATE ASSEMBLYPROTEIN V (Escherichiavirus P2) |
PF04717(Phage_base_V) | 5 | ILE A 69ALA A 71ALA A 79ILE A 23CYH A 33 | None | 1.05A | 3falC-3qr8A:undetectable | 3falC-3qr8A:24.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s5w | L-ORNITHINE5-MONOOXYGENASE (Pseudomonasaeruginosa) |
PF13434(K_oxygenase) | 5 | ILE A 419ALA A 416LEU A 25ALA A 24ILE A 376 | None | 0.86A | 3falC-3s5wA:undetectable | 3falC-3s5wA:18.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uc2 | HYPOTHETICAL PROTEINWITHIMMUNOGLOBULIN-LIKEFOLD (Pseudomonasaeruginosa) |
PF14467(DUF4426) | 5 | ILE A 59ALA A 103GLN A 104PHE A 105LEU A 88 | None | 0.95A | 3falC-3uc2A:undetectable | 3falC-3uc2A:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3v2y | SPHINGOSINE1-PHOSPHATE RECEPTOR1, LYSOZYME CHIMERA(E.C.3.2.1.17) (Escherichiavirus T4;Homo sapiens) |
PF00001(7tm_1)PF00959(Phage_lysozyme) | 5 | ALA A1129PHE A1153LEU A1133ALA A1130ILE A1078 | None | 1.04A | 3falC-3v2yA:undetectable | 3falC-3v2yA:18.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxw | ADIPONECTIN RECEPTORPROTEIN 2 (Homo sapiens) |
PF03006(HlyIII) | 5 | ILE A 322ALA A 325ALA A 326LEU A 283ALA A 279 | None | 0.72A | 3falC-3wxwA:undetectable | 3falC-3wxwA:23.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b8b | GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 1 (Saccharomycescerevisiae) |
PF16417(CNOT1_TTP_bind)PF16418(CNOT1_HEAT)PF16419(CNOT1_HEAT_N) | 5 | ILE A 741ALA A 744ALA A 745LEU A 714ALA A 715 | None | 0.76A | 3falC-4b8bA:undetectable | 3falC-4b8bA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4djh | KAPPA-TYPE OPIOIDRECEPTOR, LYSOZYME (Escherichiavirus T4;Homo sapiens) |
PF00001(7tm_1)PF00959(Phage_lysozyme) | 5 | ALA A1129PHE A1153LEU A1133ALA A1130ILE A1078 | None | 1.05A | 3falC-4djhA:undetectable | 3falC-4djhA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ia4 | AQUAPORIN (Spinaciaoleracea) |
PF00230(MIP) | 5 | ALA A 257ALA A 258GLN A 261LEU A 110ALA A 111 | None | 0.81A | 3falC-4ia4A:undetectable | 3falC-4ia4A:22.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j5x | RETINOIC ACIDRECEPTOR RXR-ALPHA,NUCLEAR RECEPTORCOACTIVATOR 1 (Homo sapiens) |
no annotation | 10 | ILE D 268ALA D 271ALA D 272GLN D 275PHE D 313ARG D 316LEU D 326ALA D 327ILE D 345CYH D 432 | None | 0.64A | 3falC-4j5xD:28.0 | 3falC-4j5xD:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lde | LYSOZYME, BETA-2ADRENERGIC RECEPTOR (Escherichiavirus T4;Homo sapiens) |
PF00001(7tm_1)PF00959(Phage_lysozyme) | 5 | ALA A 994PHE A1018LEU A 998ALA A 995ILE A 943 | None | 1.01A | 3falC-4ldeA:undetectable | 3falC-4ldeA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m88 | EXTRACELLULARLIGAND-BINDINGRECEPTOR (Verminephrobactereiseniae) |
PF13458(Peripla_BP_6) | 5 | ILE A 191ALA A 188ALA A 187LEU A 215ALA A 214 | None | 1.03A | 3falC-4m88A:undetectable | 3falC-4m88A:23.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nn1 | TRANSCRIPTIONALREGULATOR (Mycobacteriumtuberculosis) |
PF00440(TetR_N) | 5 | ILE A 12ALA A 15ALA A 16GLN A 19ALA A 35 | None | 0.50A | 3falC-4nn1A:undetectable | 3falC-4nn1A:26.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pf6 | C4-DICARBOXYLATE-BINDING PROTEIN (Roseobacterdenitrificans) |
PF03480(DctP) | 5 | ILE A 242ALA A 267ALA A 268LEU A 46ALA A 45 | None | 0.97A | 3falC-4pf6A:undetectable | 3falC-4pf6A:22.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qji | PHOSPHOPANTOTHENOYLCYSTEINEDECARBOXYLASE/PHOSPHOPANTOTHENATE--CYSTEINE LIGASE (Mycolicibacteriumsmegmatis) |
PF04127(DFP) | 5 | ALA A 277ALA A 196PHE A 332ALA A 278ILE A 405 | CTP A 500 (-4.8A)NoneNoneNoneNone | 0.99A | 3falC-4qjiA:undetectable | 3falC-4qjiA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r10 | PROTEIN HUMPBACK-2 (Caenorhabditiselegans) |
PF00514(Arm) | 5 | ILE A 443ALA A 447GLN A 508LEU A 509ILE A 436 | None | 1.04A | 3falC-4r10A:undetectable | 3falC-4r10A:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rrj | PROBABLETHREONINE--TRNALIGASE 2 (Aeropyrumpernix) |
PF08915(tRNA-Thr_ED) | 5 | ILE A 58ALA A 55ALA A 54LEU A 99ALA A 98 | None | 0.92A | 3falC-4rrjA:undetectable | 3falC-4rrjA:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4v1u | LYND (Lyngbyaaestuarii) |
PF02624(YcaO) | 5 | ILE A 264ALA A 261ALA A 260LEU A 134ALA A 133 | None | 1.06A | 3falC-4v1uA:undetectable | 3falC-4v1uA:16.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wbq | QDE-2-INTERACTINGPROTEIN (Neurosporacrassa) |
no annotation | 5 | ILE A 379ALA A 356ALA A 381LEU A 515ALA A 511 | None | 1.04A | 3falC-4wbqA:undetectable | 3falC-4wbqA:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wtv | PHOSPHATIDYLINOSITOL4-KINASE TYPE2-BETA,ENDOLYSIN,PHOSPHATIDYLINOSITOL4-KINASE TYPE 2-BETA (Escherichiavirus T4;Homo sapiens) |
PF00454(PI3_PI4_kinase)PF00959(Phage_lysozyme) | 5 | ALA A1128PHE A1152LEU A1132ALA A1129ILE A1077 | None | 1.01A | 3falC-4wtvA:undetectable | 3falC-4wtvA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xa8 | D-ISOMER SPECIFIC2-HYDROXYACIDDEHYDROGENASENAD-BINDING (Xanthobacterautotrophicus) |
PF02826(2-Hacid_dh_C) | 5 | ILE A 296ALA A 293ALA A 292LEU A 25ALA A 24 | None | 0.95A | 3falC-4xa8A:undetectable | 3falC-4xa8A:21.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xee | NEUROTENSIN RECEPTORTYPE 1, ENDOLYSINCHIMERA (Escherichiavirus T4;Rattusnorvegicus) |
PF00001(7tm_1)PF00959(Phage_lysozyme) | 5 | ALA A1129PHE A1153LEU A1133ALA A1130ILE A1078 | None | 1.02A | 3falC-4xeeA:undetectable | 3falC-4xeeA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xg0 | UNCHARACTERIZEDPROTEIN (Bordetellabronchiseptica) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | ALA A 322ALA A 321LEU A 348ALA A 347ILE A 398 | None | 0.80A | 3falC-4xg0A:undetectable | 3falC-4xg0A:20.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgj | UNCHARACTERIZEDPROTEIN (Pectobacteriumatrosepticum) |
PF07005(DUF1537)PF17042(DUF1357_C) | 5 | ILE A 211ALA A 214ALA A 215LEU A 183ALA A 184 | None | 0.69A | 3falC-4xgjA:undetectable | 3falC-4xgjA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y4m | PUTATIVE RIBOSE1,5-BISPHOSPHATEISOMERASE (Methanocaldococcusjannaschii) |
PF01946(Thi4) | 5 | ILE A 132ALA A 125ALA A 130LEU A 49ILE A 136 | None | 1.03A | 3falC-4y4mA:undetectable | 3falC-4y4mA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yk2 | BARTONELLA EFFECTORPROTEIN (BEP)SUBSTRATE OF VIRBT4SS (Bartonellaclarridgeiae) |
no annotation | 6 | ILE A 160ALA A 156PHE A 103LEU A 140ALA A 141ILE A 167 | None | 1.45A | 3falC-4yk2A:undetectable | 3falC-4yk2A:20.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zoh | PUTATIVEOXIDOREDUCTASEFAD-BINDING SUBUNIT (Sulfurisphaeratokodaii) |
PF00941(FAD_binding_5)PF03450(CO_deh_flav_C) | 5 | ILE B 236ALA B 239ALA B 240LEU B 226ALA B 222 | None | 1.01A | 3falC-4zohB:undetectable | 3falC-4zohB:25.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bt1 | HAT1-INTERACTINGFACTOR 1 (Saccharomycescerevisiae) |
no annotation | 5 | ALA A 41ALA A 42LEU A 33ALA A 29ILE A 245 | None | 0.68A | 3falC-5bt1A:2.2 | 3falC-5bt1A:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cqf | L-LYSINE6-MONOOXYGENASE (Pseudomonassyringae groupgenomosp. 3) |
PF13434(K_oxygenase) | 5 | ILE A 419ALA A 416LEU A 25ALA A 24ILE A 375 | None | 1.02A | 3falC-5cqfA:undetectable | 3falC-5cqfA:17.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5doi | TELOMERASEASSOCIATED PROTEINP45 (Tetrahymenathermophila) |
no annotation | 5 | ILE E 52ALA E 59PHE E 24LEU E 10ILE E 105 | None | 1.05A | 3falC-5doiE:undetectable | 3falC-5doiE:22.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ee7 | GLUCAGONRECEPTOR,ENDOLYSIN,GLUCAGON RECEPTOR (Escherichiavirus T4;Homo sapiens) |
PF00002(7tm_2)PF00959(Phage_lysozyme) | 5 | ALA A1127PHE A1151LEU A1131ALA A1128ILE A1076 | None | 1.02A | 3falC-5ee7A:undetectable | 3falC-5ee7A:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eut | PHOSPHATIDYLINOSITOL4-KINASE TYPE2-ALPHA,ENDOLYSIN,PHOSPHATIDYLINOSITOL4-KINASE TYPE2-ALPHA (Escherichiavirus T4;Homo sapiens) |
PF00454(PI3_PI4_kinase)PF00959(Phage_lysozyme) | 5 | ALA A1131PHE A1155LEU A1135ALA A1132ILE A1080 | None | 0.98A | 3falC-5eutA:undetectable | 3falC-5eutA:19.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5exr | DNA POLYMERASE ALPHACATALYTIC SUBUNIT (Homo sapiens) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1)PF08996(zf-DNA_Pol) | 5 | ILE C 662PHE C 622LEU C 623ALA C 624ILE C 639 | None | 1.02A | 3falC-5exrC:undetectable | 3falC-5exrC:12.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hj5 | GLUCOSAMINE-6-PHOSPHATE DEAMINASE (Vibrio cholerae) |
PF01182(Glucosamine_iso) | 5 | ILE A 20ALA A 17ALA A 16LEU A 52ALA A 51 | None | 1.01A | 3falC-5hj5A:undetectable | 3falC-5hj5A:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i14 | MUTATED ANDTRUNCATED T4LYSOZYME (Escherichiavirus T4) |
PF00959(Phage_lysozyme) | 5 | ALA A 86PHE A 110LEU A 90ALA A 87ILE A 35 | None | 0.99A | 3falC-5i14A:undetectable | 3falC-5i14A:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iud | DNA POLYMERASE ALPHACATALYTIC SUBUNIT (Homo sapiens) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 5 | ILE A 662PHE A 622LEU A 623ALA A 624ILE A 639 | None | 0.93A | 3falC-5iudA:undetectable | 3falC-5iudA:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbw | 3-HYDROXYBUTYRYL-COADEHYDRATASE (Myxococcusxanthus) |
PF00378(ECH_1) | 5 | ILE A 102ALA A 101ALA A 100ALA A 190ILE A 166 | None | 1.02A | 3falC-5jbwA:undetectable | 3falC-5jbwA:25.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mzy | GLUTACONATECOA-TRANSFERASEFAMILY, SUBUNIT A (Myxococcusxanthus) |
PF01144(CoA_trans) | 5 | ALA A 189ALA A 190PHE A 157LEU A 113ALA A 116 | None | 0.94A | 3falC-5mzyA:undetectable | 3falC-5mzyA:25.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n0g | PRECORRIN-8XMETHYLMUTASE (Rhodobactercapsulatus) |
no annotation | 5 | ILE A 73ALA A 71ALA A 130LEU A 67ALA A 66 | None | 0.92A | 3falC-5n0gA:undetectable | 3falC-5n0gA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n0g | PRECORRIN-8XMETHYLMUTASE (Rhodobactercapsulatus) |
no annotation | 5 | ILE A 73ALA A 71LEU A 89ALA A 91ILE A 160 | None | 1.01A | 3falC-5n0gA:undetectable | 3falC-5n0gA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n0g | PRECORRIN-8XMETHYLMUTASE (Rhodobactercapsulatus) |
no annotation | 5 | ILE A 196ALA A 44ALA A 43LEU A 49ILE A 160 | NoneNone8F5 A 301 ( 4.1A)NoneNone | 0.87A | 3falC-5n0gA:undetectable | 3falC-5n0gA:18.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ohs | - (-) |
no annotation | 5 | ILE A 257ALA A 260PHE A 541LEU A 538ALA A 539 | None | 0.87A | 3falC-5ohsA:undetectable | 3falC-5ohsA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojl | IMINE REDUCTASE (Aspergillusterreus) |
no annotation | 6 | ILE A 137ALA A 135ALA A 125ALA A 132ILE A 68CYH A 70 | NoneNone9X5 A 301 ( 4.8A)NoneNoneNone | 1.28A | 3falC-5ojlA:undetectable | 3falC-5ojlA:13.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ot4 | INTERAPTIN (Legionellapneumophila) |
no annotation | 5 | ILE A 574ALA A 550GLN A 549LEU A 551ILE A 537 | None | 1.05A | 3falC-5ot4A:undetectable | 3falC-5ot4A:19.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 8 | ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327ILE A 428 | 9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-3.8A)9CR A 503 (-4.7A)9CR A 503 (-3.0A)9CR A 503 (-4.3A)9CR A 503 (-3.4A)None | 1.37A | 3falC-5uanA:29.1 | 3falC-5uanA:66.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 10 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316LEU A 326ALA A 327ILE A 345CYH A 432 | 9CR A 503 (-4.0A)9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-3.8A)9CR A 503 (-4.7A)9CR A 503 (-3.0A)9CR A 503 (-4.3A)9CR A 503 (-3.4A)None9CR A 503 (-3.3A) | 0.59A | 3falC-5uanA:29.1 | 3falC-5uanA:66.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vip | MDCDMDCE (Pseudomonasaeruginosa) |
PF01039(Carboxyl_trans)PF06833(MdcE) | 5 | ILE A 111ALA A 114GLN A 113LEU A 115ILE B 189 | None | 1.02A | 3falC-5vipA:undetectable | 3falC-5vipA:24.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vip | MDCDMDCE (Pseudomonasaeruginosa) |
PF01039(Carboxyl_trans)PF06833(MdcE) | 5 | ILE A 111GLN A 113LEU A 115ALA A 116ILE B 189 | None | 1.01A | 3falC-5vipA:undetectable | 3falC-5vipA:24.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xyi | RIBOSOMAL PROTEINS19E, PUTATIVE (Trichomonasvaginalis) |
PF01090(Ribosomal_S19e) | 5 | ILE T 68ALA T 65ALA T 64LEU T 25ALA T 26 | None | 0.89A | 3falC-5xyiT:undetectable | 3falC-5xyiT:19.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yqr | ENDOLYSIN/MEMBRANE-ANCHOREDLIPID-BINDINGPROTEIN LAM6 FUSIONPROTEIN (Escherichiavirus T4;Saccharomycescerevisiae) |
no annotation | 5 | ALA A 129PHE A 153LEU A 133ALA A 130ILE A 78 | None | 1.04A | 3falC-5yqrA:undetectable | 3falC-5yqrA:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 6 | ILE A 129ALA A 132ALA A 133LEU A 267ALA A 266ILE A 180 | None | 1.13A | 3falC-6d95A:undetectable | 3falC-6d95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6eux | POLYMERASE BASICPROTEIN 2 (Influenza Bvirus) |
no annotation | 5 | ILE A 312ALA A 315ALA A 316LEU A 505ILE A 273 | None | 0.82A | 3falC-6euxA:undetectable | 3falC-6euxA:17.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5o | POLYMERASE BASICPROTEIN 2 (Influenza Bvirus) |
no annotation | 5 | ILE C 312ALA C 315ALA C 316LEU C 505ILE C 273 | None | 0.89A | 3falC-6f5oC:undetectable | 3falC-6f5oC:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gdg | TRXA,ADENOSINERECEPTOR A2A (Escherichiacoli;Homo sapiens) |
no annotation | 5 | ILE A 200ALA A 203ALA A 204GLN A 207ILE A 238 | None | 0.94A | 3falC-6gdgA:2.1 | 3falC-6gdgA:13.64 |