SIMILAR PATTERNS OF AMINO ACIDS FOR 3FAL_A_REAA501
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1air | PECTATE LYASE C (Dickeyachrysanthemi) |
PF00544(Pec_lyase_C) | 5 | ILE A 33ALA A 36ALA A 35ALA A 49VAL A 82 | None | 0.91A | 3falA-1airA:undetectable | 3falA-1airA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1al8 | GLYCOLATE OXIDASE (Spinaciaoleracea) |
PF01070(FMN_dh) | 5 | ILE A 227ALA A 246ALA A 241VAL A 141ILE A 222 | None | 1.12A | 3falA-1al8A:undetectable | 3falA-1al8A:21.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ebd | DIHYDROLIPOAMIDEDEHYDROGENASE (Geobacillusstearothermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 457ALA A 456ALA A 440VAL A 361ILE A 423 | None | 1.01A | 3falA-1ebdA:undetectable | 3falA-1ebdA:20.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7h | ALKALINE PHOSPHATASE (Pandalusborealis) |
PF00245(Alk_phosphatase) | 5 | ILE A 350ALA A 28GLN A 27ARG A 137ILE A 458 | None | 1.13A | 3falA-1k7hA:undetectable | 3falA-1k7hA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l8w | VLSE1 (Borreliellaburgdorferi) |
PF00921(Lipoprotein_2) | 5 | ILE A 174PHE A 74ALA A 78VAL A 236ILE A 235 | None | 1.04A | 3falA-1l8wA:undetectable | 3falA-1l8wA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nlu | SEDOLISIN (Pseudomonas sp.) |
no annotation | 5 | ILE A 130ALA A 121GLN A 120VAL A 294ILE A 88 | None | 1.05A | 3falA-1nluA:undetectable | 3falA-1nluA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nmo | HYPOTHETICAL PROTEINYBGI (Escherichiacoli) |
PF01784(NIF3) | 5 | ILE A 179ALA A 182ALA A 183ALA A 169ILE A 200 | None | 0.87A | 3falA-1nmoA:undetectable | 3falA-1nmoA:23.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1onf | GLUTATHIONEREDUCTASE (Plasmodiumfalciparum) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 16ALA A 17VAL A 295ILE A 293CYH A 312 | None | 0.83A | 3falA-1onfA:undetectable | 3falA-1onfA:18.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1uhl | RETINOIC ACIDRECEPTOR RXR-BETA (Homo sapiens) |
PF00104(Hormone_recep) | 10 | ILE A 339ALA A 342ALA A 343GLN A 346PHE A 384ARG A 387ALA A 398VAL A 413ILE A 416CYH A 503 | MEI A1001 (-3.8A)MEI A1001 (-3.1A)MEI A1001 (-3.3A)NoneMEI A1001 (-4.5A)MEI A1001 (-3.6A)MEI A1001 (-3.4A)MEI A1001 (-4.1A)NoneMEI A1001 (-4.0A) | 0.72A | 3falA-1uhlA:29.5 | 3falA-1uhlA:88.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vkx | PROTEIN (NF-KAPPA BP50 SUBUNIT) (Mus musculus) |
PF00554(RHD_DNA_bind)PF16179(RHD_dimer) | 5 | ILE B 494ALA B 497ALA B 498GLN B 501ILE B 460 | None | 1.13A | 3falA-1vkxB:undetectable | 3falA-1vkxB:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x0u | HYPOTHETICALMETHYLMALONYL-COADECARBOXYLASE ALPHASUBUNIT (Sulfurisphaeratokodaii) |
PF01039(Carboxyl_trans) | 5 | ILE A 316ALA A 313GLN A 314ARG A 293ILE A 354 | None | 1.05A | 3falA-1x0uA:0.5 | 3falA-1x0uA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xdi | RV3303C-LPDA (Mycobacteriumtuberculosis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 461ALA A 460ALA A 444VAL A 365ILE A 427 | None | 1.06A | 3falA-1xdiA:undetectable | 3falA-1xdiA:20.59 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xiu | RXR-LIKE PROTEIN (Biomphalariaglabrata) |
PF00104(Hormone_recep) | 10 | ILE A 242ALA A 245ALA A 246GLN A 249PHE A 287ARG A 290ALA A 301VAL A 316ILE A 319CYH A 406 | 9CR A 201 ( 4.4A)9CR A 201 (-3.6A)9CR A 201 (-3.6A)9CR A 201 (-4.1A)9CR A 201 (-4.7A)9CR A 201 (-2.8A)9CR A 201 (-3.4A)9CR A 201 (-4.2A)None9CR A 201 (-3.6A) | 0.41A | 3falA-1xiuA:30.1 | 3falA-1xiuA:81.17 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1xls | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep) | 10 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316ALA A 327VAL A 342ILE A 345CYH A 432 | 9CR A 801 (-3.9A)9CR A 801 (-3.6A)9CR A 801 (-3.5A)9CR A 801 (-4.7A)9CR A 801 (-4.3A)9CR A 801 (-2.6A)9CR A 801 (-3.3A)9CR A 801 ( 4.3A)9CR A 801 ( 4.5A)9CR A 801 ( 3.7A) | 0.37A | 3falA-1xlsA:29.3 | 3falA-1xlsA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zk7 | MERCURIC REDUCTASE (Pseudomonasaeruginosa) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 6 | ALA A 452ALA A 451GLN A 453ALA A 435VAL A 356ILE A 418 | NoneNoneGOL A3003 ( 3.8A)NoneNoneNone | 1.13A | 3falA-1zk7A:undetectable | 3falA-1zk7A:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aa4 | PUTATIVEN-ACETYLMANNOSAMINEKINASE (Escherichiacoli) |
PF00480(ROK) | 5 | ILE A 183ALA A 186ALA A 187GLN A 188VAL A 243 | None | 1.05A | 3falA-2aa4A:undetectable | 3falA-2aa4A:19.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eo4 | 150AA LONGHYPOTHETICALHISTIDINE TRIADNUCLEOTIDE-BINDINGPROTEIN (Sulfurisphaeratokodaii) |
PF01230(HIT) | 5 | ILE A 39ALA A 23ALA A 24ARG A 9ILE A 92 | NoneNoneNoneNonePO4 A 202 ( 4.6A) | 1.06A | 3falA-2eo4A:undetectable | 3falA-2eo4A:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2eq9 | PYRUVATEDEHYDROGENASECOMPLEX,DIHYDROLIPOAMIDEDEHYDROGENASE E3COMPONENT (Thermusthermophilus) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 457ALA A 456ALA A 440VAL A 361ILE A 423 | None | 1.11A | 3falA-2eq9A:undetectable | 3falA-2eq9A:20.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2gl8 | RETINOIC ACIDRECEPTOR RXR-GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 6 | PHE A 92ARG A 95ALA A 106VAL A 121ILE A 124CYH A 211 | None | 0.76A | 3falA-2gl8A:27.7 | 3falA-2gl8A:85.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iec | UNCHARACTERIZEDPROTEIN CONSERVED INARCHAEA (Methanopyruskandleri) |
PF04038(DHNA) | 5 | ILE A 49ALA A 52ALA A 53GLN A 56VAL A 66 | None | 1.13A | 3falA-2iecA:undetectable | 3falA-2iecA:19.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k3o | TUSP1 (Nephilaantipodiana) |
PF12042(RP1-2) | 5 | ILE A 81ALA A 84ALA A 85ALA A 60ILE A 21 | None | 1.04A | 3falA-2k3oA:undetectable | 3falA-2k3oA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m64 | PHLP5 (Phleum pratense) |
PF01620(Pollen_allerg_2) | 5 | ILE A 224ALA A 196PHE A 220ALA A 219ILE A 238 | None | 1.10A | 3falA-2m64A:undetectable | 3falA-2m64A:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m64 | PHLP5 (Phleum pratense) |
PF01620(Pollen_allerg_2) | 5 | ILE A 224ALA A 223PHE A 220ALA A 219ILE A 238 | None | 1.08A | 3falA-2m64A:undetectable | 3falA-2m64A:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p6t | TRANSCRIPTIONALREGULATOR, LRP/ASNCFAMILY (Neisseriameningitidis) |
PF01037(AsnC_trans_reg)PF13412(HTH_24) | 5 | ILE A 72ALA A 70ALA A 112GLN A 69VAL A 134 | None | 1.11A | 3falA-2p6tA:undetectable | 3falA-2p6tA:23.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2q60 | RETINOID X RECEPTOR (Polyandrocarpamisakiensis) |
PF00104(Hormone_recep) | 6 | PHE A 188ARG A 191ALA A 202VAL A 217ILE A 220CYH A 307 | None | 0.70A | 3falA-2q60A:26.9 | 3falA-2q60A:72.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yik | ENDOGLUCANASE (Ruminiclostridiumthermocellum) |
PF00759(Glyco_hydro_9) | 5 | ILE A 328ALA A 287ALA A 286VAL A 405ILE A 402 | None | 1.08A | 3falA-2yikA:undetectable | 3falA-2yikA:16.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z5x | AMINE OXIDASE[FLAVIN-CONTAINING]A (Homo sapiens) |
PF01593(Amino_oxidase) | 5 | ALA A 28ALA A 29ALA A 456VAL A 244ILE A 256 | NoneNoneNoneFAD A 600 ( 4.0A)None | 1.13A | 3falA-2z5xA:undetectable | 3falA-2z5xA:18.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b02 | TRANSCRIPTIONALREGULATOR, CRPFAMILY (Thermusthermophilus) |
PF00027(cNMP_binding)PF13545(HTH_Crp_2) | 5 | ILE A 145ARG A 115ALA A 150VAL A 176ILE A 169 | None | 1.09A | 3falA-3b02A:undetectable | 3falA-3b02A:26.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b2g | FERREDOXIN-1 (Leptolyngbyaboryana) |
PF00111(Fer2) | 5 | ILE A 26ALA A 29ALA A 30GLN A 33ILE A 53 | None | 1.10A | 3falA-3b2gA:undetectable | 3falA-3b2gA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bj1 | HEMOGLOBIN ALPHAHEMOGLOBIN BETA (Percaflavescens) |
PF00042(Globin) | 5 | ILE B 112ALA B 115ALA B 116ARG A 31VAL B 34 | None | 1.08A | 3falA-3bj1B:undetectable | 3falA-3bj1B:20.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cgd | PYRIDINENUCLEOTIDE-DISULFIDEOXIDOREDUCTASE,CLASS I (Bacillusanthracis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 15ALA A 16VAL A 266ILE A 264CYH A 283 | None | 0.96A | 3falA-3cgdA:undetectable | 3falA-3cgdA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dkn | PREPROTEINTRANSLOCASE SUBUNITSECY (Canis lupus) |
PF00344(SecY) | 5 | ILE A 174ALA A 175ALA A 176VAL A 79ILE A 78 | None | 0.99A | 3falA-3dknA:undetectable | 3falA-3dknA:19.64 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3dzu | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
PF00104(Hormone_recep)PF00105(zf-C4) | 10 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316ALA A 327VAL A 342ILE A 345CYH A 432 | 9CR A7223 (-3.9A)9CR A7223 (-3.5A)9CR A7223 (-4.2A)9CR A7223 (-4.6A)9CR A7223 (-4.5A)9CR A7223 (-3.7A)9CR A7223 ( 4.7A)9CR A7223 ( 4.5A)9CR A7223 ( 4.9A)9CR A7223 (-3.8A) | 0.78A | 3falA-3dzuA:29.5 | 3falA-3dzuA:51.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f8r | THIOREDOXINREDUCTASE (TRXB-3) (Sulfolobussolfataricus) |
PF07992(Pyr_redox_2) | 5 | ALA A 30ALA A 31VAL A 271ILE A 269CYH A 288 | None | 1.03A | 3falA-3f8rA:undetectable | 3falA-3f8rA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fmf | DETHIOBIOTINSYNTHETASE (Mycobacteriumtuberculosis) |
PF13500(AAA_26) | 5 | ALA A 133ALA A 134ALA A 132VAL A 33ILE A 31 | NoneCSX A 163 ( 4.9A)NoneNoneNone | 1.05A | 3falA-3fmfA:undetectable | 3falA-3fmfA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fq8 | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE (Synechococcuselongatus) |
PF00202(Aminotran_3) | 5 | ILE A1275PHE A1119ALA A1312VAL A1111ILE A1114 | None | 1.06A | 3falA-3fq8A:undetectable | 3falA-3fq8A:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g23 | LD-CARBOXYPEPTIDASEA (Novosphingobiumaromaticivorans) |
PF02016(Peptidase_S66) | 5 | ALA A 9PHE A 42ALA A 49VAL A 22ILE A 23 | None | 1.00A | 3falA-3g23A:undetectable | 3falA-3g23A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h7a | SHORT CHAINDEHYDROGENASE (Rhodopseudomonaspalustris) |
PF00106(adh_short) | 5 | ILE A 21ALA A 22ALA A 19ALA A 34ILE A 183 | ILE A 21 ( 0.6A)ALA A 22 ( 0.0A)ALA A 19 ( 0.0A)ALA A 34 ( 0.0A)ILE A 183 ( 0.7A) | 1.09A | 3falA-3h7aA:undetectable | 3falA-3h7aA:23.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iwa | FAD-DEPENDENTPYRIDINENUCLEOTIDE-DISULPHIDE OXIDOREDUCTASE (Desulfovibriovulgaris) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 17ALA A 18VAL A 277ILE A 275CYH A 294 | None | 0.73A | 3falA-3iwaA:undetectable | 3falA-3iwaA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iwa | FAD-DEPENDENTPYRIDINENUCLEOTIDE-DISULPHIDE OXIDOREDUCTASE (Desulfovibriovulgaris) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ILE A 321ALA A 17ALA A 18VAL A 277ILE A 275 | None | 1.06A | 3falA-3iwaA:undetectable | 3falA-3iwaA:20.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j0l | RIBOSOMAL PROTEINS14 (Oryctolaguscuniculus) |
PF00411(Ribosomal_S11) | 5 | ILE K 42ALA K 77ALA K 74GLN K 76ILE K 95 | None | 1.09A | 3falA-3j0lK:undetectable | 3falA-3j0lK:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kyf | PUTATIVEUNCHARACTERIZEDPROTEIN (Pseudomonasputida) |
PF07238(PilZ)PF07317(YcgR) | 5 | ALA A 224GLN A 225PHE A 217VAL A 136ILE A 138 | None | 1.00A | 3falA-3kyfA:undetectable | 3falA-3kyfA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lqy | PUTATIVEISOCHORISMATASEHYDROLASE (Oleispiraantarctica) |
PF00857(Isochorismatase) | 5 | ALA A 146ALA A 35GLN A 38ALA A 182ILE A 77 | None | 0.93A | 3falA-3lqyA:undetectable | 3falA-3lqyA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o85 | RIBOSOMAL PROTEINL7AE (Giardiaintestinalis) |
PF01248(Ribosomal_L7Ae) | 5 | ILE A 101ALA A 99ALA A 39VAL A 110ILE A 114 | None | 1.08A | 3falA-3o85A:undetectable | 3falA-3o85A:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oc4 | OXIDOREDUCTASE,PYRIDINENUCLEOTIDE-DISULFIDEFAMILY (Enterococcusfaecalis) |
PF02852(Pyr_redox_dim)PF07992(Pyr_redox_2) | 5 | ALA A 15ALA A 16VAL A 261ILE A 259CYH A 278 | None | 0.92A | 3falA-3oc4A:undetectable | 3falA-3oc4A:19.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pfe | SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE (Legionellapneumophila) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 5 | ILE A 141ALA A 143GLN A 14VAL A 91ILE A 187 | None | 1.01A | 3falA-3pfeA:undetectable | 3falA-3pfeA:18.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r11 | ENZYME OF ENOLASESUPERFAMILY (Francisellaphilomiragia) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 282ALA A 279GLN A 280VAL A 257ILE A 258 | None | 1.08A | 3falA-3r11A:undetectable | 3falA-3r11A:19.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s4w | FANCONI ANEMIA GROUPD2 PROTEIN HOMOLOG (Mus musculus) |
PF14631(FancD2) | 5 | ILE B 366ALA B 365ALA B 297ILE B 410CYH B 409 | None | 1.13A | 3falA-3s4wB:undetectable | 3falA-3s4wB:12.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sky | COPPER-EXPORTINGP-TYPE ATPASE B (Archaeoglobusfulgidus) |
PF00702(Hydrolase) | 5 | ILE A 433ALA A 437ARG A 514VAL A 469ILE A 499 | None | 1.08A | 3falA-3skyA:undetectable | 3falA-3skyA:22.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u8p | CYTOCHROME B562INTEGRAL FUSION WITHENHANCED GREENFLUORESCENT PROTEIN (Aequoreavictoria;Escherichiacoli) |
PF01353(GFP)PF07361(Cytochrom_B562) | 5 | ALA A 78ALA A 77ALA A 82VAL A 58ILE A 59 | None | 1.13A | 3falA-3u8pA:undetectable | 3falA-3u8pA:22.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wc3 | ENDO-1,4-BETA-GLUCANASE (Eisenia fetida) |
PF00759(Glyco_hydro_9) | 5 | ALA A 177PHE A 87ALA A 86VAL A 335ILE A 332 | None | 1.10A | 3falA-3wc3A:undetectable | 3falA-3wc3A:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4atw | ALPHA-L-ARABINOFURANOSIDASE DOMAINPROTEIN (Thermotogamaritima) |
PF06964(Alpha-L-AF_C) | 5 | ALA A 394ALA A 408PHE A 471VAL A 463ILE A 461 | None | 1.13A | 3falA-4atwA:undetectable | 3falA-4atwA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b7x | PROBABLEOXIDOREDUCTASE (Pseudomonasaeruginosa) |
PF00107(ADH_zinc_N)PF16884(ADH_N_2) | 5 | ILE A 178ALA A 179ALA A 157ILE A 217CYH A 213 | NoneNAP A 400 (-3.7A)NoneNoneNone | 1.10A | 3falA-4b7xA:undetectable | 3falA-4b7xA:22.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bwc | PHOSPHOLIPASE B-LIKE1 (Bos taurus) |
PF04916(Phospholip_B) | 5 | ILE A 95ALA A 98ALA A 99ALA A 42VAL B 263 | None | 1.11A | 3falA-4bwcA:undetectable | 3falA-4bwcA:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3y | 3-KETOSTEROIDDEHYDROGENASE (Rhodococcuserythropolis) |
PF00890(FAD_binding_2) | 5 | ALA A 228ALA A 19ALA A 475VAL A 210ILE A 219 | FAD A 551 ( 4.8A)NoneNoneNoneNone | 1.05A | 3falA-4c3yA:undetectable | 3falA-4c3yA:19.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4dix | PLECTIN-RELATEDPROTEIN (Arabidopsisthaliana) |
PF16709(SCAB-IgPH) | 5 | ILE A 457ALA A 458ALA A 444GLN A 443ILE A 411 | None | 1.05A | 3falA-4dixA:undetectable | 3falA-4dixA:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ds3 | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Brucellamelitensis) |
PF00551(Formyl_trans_N) | 5 | ALA A 24ALA A 23GLN A 25VAL A 139ILE A 110 | None | 0.87A | 3falA-4ds3A:undetectable | 3falA-4ds3A:26.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e6u | ACYL-[ACYL-CARRIER-PROTEIN]--UDP-N-ACETYLGLUCOSAMINEO-ACYLTRANSFERASE (Acinetobacterbaumannii) |
PF00132(Hexapep)PF13720(Acetyltransf_11) | 5 | ILE A 221ALA A 231GLN A 234VAL A 184ILE A 196 | None | 1.00A | 3falA-4e6uA:undetectable | 3falA-4e6uA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdw | LEUCINE RICHHYPOTHETICAL PROTEIN (Bacteroidesovatus) |
PF07523(Big_3)PF13306(LRR_5) | 5 | ALA A 290GLN A 269VAL A 280ILE A 277CYH A 297 | None | 1.06A | 3falA-4fdwA:undetectable | 3falA-4fdwA:24.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4itu | SHORT-CHAINDEHYDROGENASE/REDUCTASE SDR (Xanthobacterautotrophicus) |
PF13561(adh_short_C2) | 5 | ILE A 12ALA A 35ALA A 44VAL A 230ILE A 231 | None | 0.98A | 3falA-4ituA:undetectable | 3falA-4ituA:23.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j5x | RETINOIC ACIDRECEPTOR RXR-ALPHA,NUCLEAR RECEPTORCOACTIVATOR 1 (Homo sapiens) |
no annotation | 10 | ILE D 268ALA D 271ALA D 272GLN D 275PHE D 313ARG D 316ALA D 327VAL D 342ILE D 345CYH D 432 | None | 0.57A | 3falA-4j5xD:27.8 | 3falA-4j5xD:100.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4j5x | RETINOIC ACIDRECEPTOR RXR-ALPHA,NUCLEAR RECEPTORCOACTIVATOR 1 (Homo sapiens) |
no annotation | 7 | ILE D 268ALA D 271GLN D 275PHE D 313VAL D 342ILE D 345CYH D 432 | None | 1.45A | 3falA-4j5xD:27.8 | 3falA-4j5xD:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jz7 | CARBAMATE KINASE (Giardiaintestinalis) |
PF00696(AA_kinase) | 5 | ILE A 39ALA A 36ALA A 35ALA A 96VAL A 7 | None | 0.83A | 3falA-4jz7A:undetectable | 3falA-4jz7A:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kf7 | NUP188 (Thermothelomycesthermophila) |
PF10487(Nup188) | 5 | ALA A 822ALA A 821VAL A 915ILE A 840CYH A 837 | None | 1.04A | 3falA-4kf7A:undetectable | 3falA-4kf7A:12.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n4w | CYTOCHROMEB(562),SMOOTHENEDHOMOLOG (Homo sapiens;Shigellaflexneri) |
PF01534(Frizzled)PF07361(Cytochrom_B562) | 5 | ALA A 36ALA A 35ALA A 40VAL A 16ILE A 17 | None | 1.09A | 3falA-4n4wA:undetectable | 3falA-4n4wA:21.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nn1 | TRANSCRIPTIONALREGULATOR (Mycobacteriumtuberculosis) |
PF00440(TetR_N) | 5 | ILE A 12ALA A 15ALA A 16GLN A 19ALA A 35 | None | 0.49A | 3falA-4nn1A:undetectable | 3falA-4nn1A:26.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ntj | P2Y PURINOCEPTOR12,SOLUBLECYTOCHROME B562,P2YPURINOCEPTOR 12 (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 5 | ALA A1036ALA A1035ALA A1040VAL A1016ILE A1017 | None | 1.12A | 3falA-4ntjA:undetectable | 3falA-4ntjA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o9r | SMOOTHENEDHOMOLOG/SOLUBLECYTOCHROME B562CHIMERIC PROTEIN (Escherichiacoli;Homo sapiens) |
PF01534(Frizzled)PF07361(Cytochrom_B562) | 5 | ALA A1036ALA A1035ALA A1040VAL A1016ILE A1017 | None | 1.07A | 3falA-4o9rA:undetectable | 3falA-4o9rA:20.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p56 | PUTATIVEEXTRACELLULARSOLUTE-BINDINGPROTEIN (Bordetellabronchiseptica) |
PF03480(DctP) | 5 | ILE A 53ALA A 56ARG A 260VAL A 87ILE A 242 | None | 1.11A | 3falA-4p56A:undetectable | 3falA-4p56A:24.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pq9 | BETA-1,3-GLUCANASE (Mycobacteriummarinum) |
PF00722(Glyco_hydro_16) | 6 | ILE A 90ALA A 101ALA A 92ARG A 55VAL A 252ILE A 120 | None | 1.26A | 3falA-4pq9A:undetectable | 3falA-4pq9A:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qji | PHOSPHOPANTOTHENOYLCYSTEINEDECARBOXYLASE/PHOSPHOPANTOTHENATE--CYSTEINE LIGASE (Mycolicibacteriumsmegmatis) |
PF04127(DFP) | 5 | ALA A 277ALA A 196PHE A 332ALA A 278ILE A 405 | CTP A 500 (-4.8A)NoneNoneNoneNone | 1.04A | 3falA-4qjiA:undetectable | 3falA-4qjiA:23.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rt6 | HEMOPEXIN (Oryctolaguscuniculus) |
PF00045(Hemopexin) | 5 | ILE B 88ALA B 76ALA B 77PHE B 138ALA B 122 | None | 1.03A | 3falA-4rt6B:undetectable | 3falA-4rt6B:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rwa | SOLUBLE CYTOCHROMEB562,DELTA-TYPEOPIOID RECEPTOR (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 5 | ALA A1036ALA A1035ALA A1040VAL A1016ILE A1017 | None | 1.09A | 3falA-4rwaA:2.4 | 3falA-4rwaA:18.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tv6 | 2-DEHYDRO-3-DEOXYGLUCARATE ALDOLASE (Staphylococcusaureus) |
PF03328(HpcH_HpaI) | 5 | ILE A 33ALA A 34ALA A 35ALA A 65ILE A 241 | None | 1.12A | 3falA-4tv6A:undetectable | 3falA-4tv6A:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wop | ATP-DEPENDENTDETHIOBIOTINSYNTHETASE BIOD (Mycobacteriumtuberculosis) |
PF13500(AAA_26) | 5 | ALA A 133ALA A 134ALA A 132VAL A 33ILE A 31 | None | 1.09A | 3falA-4wopA:undetectable | 3falA-4wopA:21.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y4n | PUTATIVE RIBOSE1,5-BISPHOSPHATEISOMERASE (Methanotorrisigneus) |
PF01946(Thi4) | 5 | ALA A 44ALA A 45ALA A 252VAL A 146ILE A 165 | None | 1.10A | 3falA-4y4nA:undetectable | 3falA-4y4nA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z36 | LYSOPHOSPHATIDICACID RECEPTOR1,SOLUBLE CYTOCHROMEB562 (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 5 | ALA A1036ALA A1035ALA A1040VAL A1016ILE A1017 | None | 1.09A | 3falA-4z36A:undetectable | 3falA-4z36A:19.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4zud | CHIMERA PROTEIN OFSOLUBLE CYTOCHROMEB562 AND TYPE-1ANGIOTENSIN IIRECEPTOR (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 5 | ALA A1036ALA A1035ALA A1040VAL A1016ILE A1017 | None | 1.12A | 3falA-4zudA:undetectable | 3falA-4zudA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5n | LH3HEXON-INTERLACINGCAPSID PROTEIN (Snakeatadenovirus A) |
PF01696(Adeno_E1B_55K) | 5 | ILE A 179ALA A 145VAL A 165ILE A 132CYH A 127 | None | 0.89A | 3falA-5g5nA:undetectable | 3falA-5g5nA:18.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h3k | SLR0280 PROTEIN (Synechocystissp. PCC 6803) |
no annotation | 5 | ALA A 151ALA A 192GLN A 152VAL A 250ILE A 261 | None | 1.08A | 3falA-5h3kA:undetectable | 3falA-5h3kA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hdm | GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE1, CHLOROPLASTIC (Arabidopsisthaliana) |
PF00202(Aminotran_3) | 5 | ILE A 276PHE A 120ALA A 313VAL A 112ILE A 115 | None | 1.03A | 3falA-5hdmA:undetectable | 3falA-5hdmA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jbw | 3-HYDROXYBUTYRYL-COADEHYDRATASE (Myxococcusxanthus) |
PF00378(ECH_1) | 5 | ILE A 102ALA A 101ALA A 100ALA A 190ILE A 166 | None | 1.01A | 3falA-5jbwA:undetectable | 3falA-5jbwA:25.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jo7 | VETISPIRADIENESYNTHASE 1 (Hyoscyamusmuticus) |
PF01397(Terpene_synth)PF03936(Terpene_synth_C) | 5 | ILE A 439ALA A 442ALA A 494VAL A 508ILE A 512 | None | 0.98A | 3falA-5jo7A:undetectable | 3falA-5jo7A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l6m | RIBONUCLEASE VAPC (Caulobactervibrioides) |
PF01850(PIN) | 5 | ILE B 82ALA B 100ALA B 99GLN B 101ALA B 75 | None | 1.04A | 3falA-5l6mB:undetectable | 3falA-5l6mB:19.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n2s | SOLUBLE CYTOCHROMEB562,ADENOSINERECEPTOR A1 (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 5 | ALA A1036ALA A1035ALA A1040VAL A1016ILE A1017 | None | 1.09A | 3falA-5n2sA:2.1 | 3falA-5n2sA:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nj6 | PROTEINASE-ACTIVATEDRECEPTOR 2,SOLUBLECYTOCHROMEB562,PROTEINASE-ACTIVATED RECEPTOR 2 (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 5 | ALA A2035ALA A2034ALA A2039VAL A2015ILE A2016 | None | 1.10A | 3falA-5nj6A:undetectable | 3falA-5nj6A:19.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ojl | IMINE REDUCTASE (Aspergillusterreus) |
no annotation | 6 | ILE A 137ALA A 135ALA A 125ALA A 132ILE A 68CYH A 70 | NoneNone9X5 A 301 ( 4.8A)NoneNoneNone | 1.25A | 3falA-5ojlA:undetectable | 3falA-5ojlA:13.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tem | 4-HYDROXY-TETRAHYDRODIPICOLINATEREDUCTASE (Vibriovulnificus) |
no annotation | 5 | ALA C 30ALA C 31GLN C 68VAL C 96ILE C 95 | None | 1.05A | 3falA-5temC:undetectable | 3falA-5temC:21.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5txr | 5-AMINOLEVULINATESYNTHASE,MITOCHONDRIAL (Saccharomycescerevisiae) |
no annotation | 5 | ILE B 331ALA B 347ALA B 348ALA B 168ILE B 264 | None | 0.92A | 3falA-5txrB:undetectable | 3falA-5txrB:15.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u1d | ANTIGEN PEPTIDETRANSPORTER 1ANTIGEN PEPTIDETRANSPORTER 2 (Homo sapiens) |
PF00005(ABC_tran)PF00664(ABC_membrane) | 5 | ILE B 193ALA B 192PHE B 189ALA B 188VAL A 424 | None | 1.11A | 3falA-5u1dB:undetectable | 3falA-5u1dB:16.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 7 | ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316ALA A 327ILE A 428 | 9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-3.8A)9CR A 503 (-4.7A)9CR A 503 (-3.0A)9CR A 503 (-3.4A)None | 1.40A | 3falA-5uanA:28.7 | 3falA-5uanA:66.30 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5uan | RETINOIC ACIDRECEPTOR RXR-ALPHA (Homo sapiens) |
no annotation | 10 | ILE A 268ALA A 271ALA A 272GLN A 275PHE A 313ARG A 316ALA A 327VAL A 342ILE A 345CYH A 432 | 9CR A 503 (-4.0A)9CR A 503 (-3.5A)9CR A 503 (-3.5A)9CR A 503 (-3.8A)9CR A 503 (-4.7A)9CR A 503 (-3.0A)9CR A 503 (-3.4A)NoneNone9CR A 503 (-3.3A) | 0.64A | 3falA-5uanA:28.7 | 3falA-5uanA:66.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ung | CHIMERA PROTEIN OFTYPE-2 ANGIOTENSINII RECEPTOR ANDSOLUBLE CYTOCHROMEB562 (Escherichiacoli;Homo sapiens) |
PF00001(7tm_1)PF07361(Cytochrom_B562) | 5 | ALA B1036ALA B1035ALA B1040VAL B1016ILE B1017 | None | 1.10A | 3falA-5ungB:undetectable | 3falA-5ungB:20.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c2h | CYSTATHIONINEBETA-SYNTHASE (Saccharomycescerevisiae) |
no annotation | 5 | ILE A 39ALA A 315ALA A 41PHE A 294ALA A 293 | None | 1.04A | 3falA-6c2hA:undetectable | 3falA-6c2hA:15.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cbo | C-6'AMINOTRANSFERASE (Micromonosporaechinospora) |
no annotation | 5 | ILE A 45ALA A 34PHE A 353ALA A 352ILE A 365 | None | 0.98A | 3falA-6cboA:undetectable | 3falA-6cboA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6cmz | DIHYDROLIPOYLDEHYDROGENASE (Burkholderiacenocepacia) |
no annotation | 5 | ALA A 20ALA A 21ALA A 329VAL A 126ILE A 137 | None | 1.03A | 3falA-6cmzA:undetectable | 3falA-6cmzA:26.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6d95 | - (-) |
no annotation | 5 | ILE A 129ALA A 132ALA A 133ALA A 266ILE A 180 | None | 0.87A | 3falA-6d95A:undetectable | 3falA-6d95A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f4f | GLUTATHIONETRANSFERASE (Trametesversicolor) |
no annotation | 5 | ILE A 88ALA A 28ALA A 30ALA A 95ILE A 78 | None | 1.08A | 3falA-6f4fA:undetectable | 3falA-6f4fA:14.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gdg | TRXA,ADENOSINERECEPTOR A2A (Escherichiacoli;Homo sapiens) |
no annotation | 5 | ALA A 203ALA A 204GLN A 207VAL A 239ILE A 238 | None | 0.94A | 3falA-6gdgA:2.1 | 3falA-6gdgA:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gdg | TRXA,ADENOSINERECEPTOR A2A (Escherichiacoli;Homo sapiens) |
no annotation | 5 | ILE A 200ALA A 203ALA A 204GLN A 207ILE A 238 | None | 0.90A | 3falA-6gdgA:2.1 | 3falA-6gdgA:13.64 |