SIMILAR PATTERNS OF AMINO ACIDS FOR 3EM0_B_CHDB153_0

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ci9 PROTEIN
(CARBOXYLESTERASE)

(Burkholderia
gladioli) 		PF00144
(Beta-lactamase) 		4 ILE A 152
PHE A 227
PHE A 265
GLY A 244
 None
 1.11A 3em0B-1ci9A:
0.3		 3em0B-1ci9A:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g71 DNA PRIMASE

(Pyrococcus
furiosus) 		PF01896
(DNA_primase_S) 		4 PHE A 255
PHE A 268
LYS A 266
GLY A 226
 None
 1.00A 3em0B-1g71A:
0.0		 3em0B-1g71A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1idu VANADIUM
CHLOROPEROXIDASE

(Curvularia
inaequalis) 		PF01569
(PAP2) 		4 ILE A  61
PHE A  74
TYR A  65
GLY A 162
 None
 1.11A 3em0B-1iduA:
0.0		 3em0B-1iduA:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ikt ESTRADIOL 17
BETA-DEHYDROGENASE 4

(Homo sapiens) 		PF02036
(SCP2) 		4 ILE A  44
PHE A  12
PHE A  79
GLY A  41
 None
None
OXN  A 123 ( 4.4A)
None
 0.70A 3em0B-1iktA:
0.1		 3em0B-1iktA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ikt ESTRADIOL 17
BETA-DEHYDROGENASE 4

(Homo sapiens) 		PF02036
(SCP2) 		4 ILE A  44
PHE A  12
PHE A  79
GLY A  42
 None
None
OXN  A 123 ( 4.4A)
None
 1.10A 3em0B-1iktA:
0.1		 3em0B-1iktA:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1k27 5'-DEOXY-5'-METHYLTH
IOADENOSINE
PHOSPHORYLASE

(Homo sapiens) 		PF01048
(PNP_UDP_1) 		4 ILE A  78
PHE A 144
TYR A 212
GLY A 209
 None
 0.85A 3em0B-1k27A:
undetectable		 3em0B-1k27A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p3c GLUTAMYL-ENDOPEPTIDA
SE

(Bacillus
intermedius) 		PF00089
(Trypsin) 		4 ILE A 101
PHE A 208
PHE A  98
GLY A  34
 None
 1.06A 3em0B-1p3cA:
0.0		 3em0B-1p3cA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qle CYTOCHROME C OXIDASE
POLYPEPTIDE I-BETA

(Paracoccus
denitrificans) 		PF00115
(COX1) 		4 ILE A 294
PHE A 449
PHE A 422
GLY A 288
 None
 0.67A 3em0B-1qleA:
0.0		 3em0B-1qleA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1r8w GLYCEROL DEHYDRATASE

(Clostridium
butyricum) 		PF01228
(Gly_radical)
PF02901
(PFL-like) 		4 ILE A 775
PHE A 450
PHE A 333
GLY A 106
 None
 1.04A 3em0B-1r8wA:
0.0		 3em0B-1r8wA:
12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v33 DNA PRIMASE SMALL
SUBUNIT

(Pyrococcus
horikoshii) 		PF01896
(DNA_primase_S) 		4 PHE A 255
PHE A 268
LYS A 266
GLY A 226
 None
 1.09A 3em0B-1v33A:
0.0		 3em0B-1v33A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w85 PYRUVATE
DEHYDROGENASE E1
COMPONENT, ALPHA
SUBUNIT
PYRUVATE
DEHYDROGENASE E1
COMPONENT, BETA
SUBUNIT

(Geobacillus
stearothermophilus;
Geobacillus
stearothermophilus) 		PF00676
(E1_dh)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 PHE B  53
PHE A 191
LYS A 192
GLY A 255
 PEG  A1369 ( 4.2A)
PEG  A1369 (-4.8A)
None
None
 0.81A 3em0B-1w85B:
undetectable		 3em0B-1w85B:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w8i PUTATIVE VAPC
RIBONUCLEASE AF_1683

(Archaeoglobus
fulgidus) 		PF01850
(PIN) 		4 ILE A 154
PHE A  10
PHE A  63
LYS A  62
 None
 0.81A 3em0B-1w8iA:
undetectable		 3em0B-1w8iA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wzn SAM-DEPENDENT
METHYLTRANSFERASE

(Pyrococcus
horikoshii) 		PF13649
(Methyltransf_25) 		4 ILE A 228
PHE A 141
PHE A 223
LYS A 225
 None
 1.09A 3em0B-1wznA:
3.5		 3em0B-1wznA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfi UNKNOWN PROTEIN

(Arabidopsis
thaliana) 		PF01937
(DUF89) 		4 ILE A 230
PHE A 203
PHE A 360
GLY A 162
 None
 1.05A 3em0B-1xfiA:
undetectable		 3em0B-1xfiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ydw AX110P-LIKE PROTEIN

(Arabidopsis
thaliana) 		PF01408
(GFO_IDH_MocA) 		4 ILE A 222
PHE A 162
PHE A 160
GLY A 226
 None
 0.94A 3em0B-1ydwA:
1.6		 3em0B-1ydwA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z94 CONSERVED
HYPOTHETICAL PROTEIN

(Chromobacterium
violaceum) 		PF08327
(AHSA1) 		4 ILE A 117
PHE A  56
PHE A  67
GLY A  93
 None
 1.05A 3em0B-1z94A:
3.0		 3em0B-1z94A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aa1 HEMOGLOBIN BETA-C
CHAIN

(Trematomus
newnesi) 		PF00042
(Globin) 		4 ILE B  81
PHE B  15
PHE B 130
LYS B 132
 None
 1.08A 3em0B-2aa1B:
undetectable		 3em0B-2aa1B:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dcq PUTATIVE PROTEIN
AT4G01050

(Arabidopsis
thaliana) 		no annotation 4 ILE A  27
PHE A  99
LYS A  58
GLY A  55
 None
 1.02A 3em0B-2dcqA:
undetectable		 3em0B-2dcqA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dnu SH3 MULTIPLE DOMAINS
1

(Homo sapiens) 		PF07653
(SH3_2) 		4 ILE A  36
PHE A  27
LYS A  10
GLY A   7
 None
 0.91A 3em0B-2dnuA:
undetectable		 3em0B-2dnuA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fnc MALTOSE ABC
TRANSPORTER,
PERIPLASMIC
MALTOSE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF13416
(SBP_bac_8) 		4 ILE A 229
PHE A 157
PHE A 262
GLY A 231
 None
 0.89A 3em0B-2fncA:
undetectable		 3em0B-2fncA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fpr HISTIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
HISB

(Escherichia
coli) 		PF08645
(PNK3P) 		4 PHE A  81
PHE A  88
LYS A  50
GLY A  48
 None
 1.09A 3em0B-2fprA:
undetectable		 3em0B-2fprA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ghb MALTOSE ABC
TRANSPORTER,
PERIPLASMIC
MALTOSE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF13416
(SBP_bac_8) 		4 ILE A 229
PHE A 157
PHE A 262
GLY A 231
 None
 0.99A 3em0B-2ghbA:
undetectable		 3em0B-2ghbA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gtt NUCLEOPROTEIN

(Rabies
lyssavirus) 		PF00945
(Rhabdo_ncap) 		4 ILE A 249
PHE A 309
PHE A 438
GLY A 346
 None
 1.05A 3em0B-2gttA:
undetectable		 3em0B-2gttA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hq8 COELENTERAZINE-BINDI
NG PROTEIN CA-BOUND
APO FORM

(Renilla
muelleri) 		PF13202
(EF-hand_5)
PF13499
(EF-hand_7) 		4 ILE A  39
PHE A 160
PHE A 180
GLY A 132
 None
 1.00A 3em0B-2hq8A:
undetectable		 3em0B-2hq8A:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf7 STRICTOSIDINE-O-BETA
-D-GLUCOSIDASE

(Rauvolfia
serpentina) 		PF00232
(Glyco_hydro_1) 		4 PHE A  43
PHE A  49
TYR A 462
GLY A 341
 None
 1.06A 3em0B-2jf7A:
undetectable		 3em0B-2jf7A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2lba BABP PROTEIN

(Gallus gallus) 		PF14651
(Lipocalin_7) 		4 ILE A  21
PHE A  79
PHE A  94
TYR A  97
 CHO  A 201 ( 4.3A)
CHO  A 201 (-3.5A)
CHO  A 201 (-2.9A)
CHO  A 201 (-2.6A)
 0.86A 3em0B-2lbaA:
19.7		 3em0B-2lbaA:
60.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2lm5 CALCIUM AND
INTEGRIN-BINDING
PROTEIN 1

(Homo sapiens) 		PF13499
(EF-hand_7) 		4 ILE A 153
PHE A 115
PHE A 173
GLY A 166
 None
 0.89A 3em0B-2lm5A:
undetectable		 3em0B-2lm5A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r4j AEROBIC
GLYCEROL-3-PHOSPHATE
DEHYDROGENASE

(Escherichia
coli) 		PF01266
(DAO)
PF16901
(DAO_C) 		5 ILE A 101
PHE A 257
PHE A  87
TYR A 141
GLY A 122
 BOG  A 800 ( 4.0A)
None
None
None
None
 1.24A 3em0B-2r4jA:
undetectable		 3em0B-2r4jA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Paraburkholderia
phytofirmans) 		PF00903
(Glyoxalase) 		4 ILE A  41
PHE A  57
TYR A  53
GLY A  72
 None
 1.04A 3em0B-2rbbA:
undetectable		 3em0B-2rbbA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wwe PHOSPHOINOSITIDE-3-K
INASE, CLASS 2,
GAMMA POLYPEPTIDE

(Homo sapiens) 		PF00787
(PX) 		4 ILE A1222
PHE A1260
PHE A1238
GLY A1211
 None
 1.05A 3em0B-2wweA:
undetectable		 3em0B-2wweA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x2g TRIOSEPHOSPHATE
ISOMERASE,
GLYCOSOMAL

(Trypanosoma
brucei) 		PF00121
(TIM) 		4 ILE A  91
PHE A  86
LYS A  84
GLY A 120
 None
 0.92A 3em0B-2x2gA:
undetectable		 3em0B-2x2gA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE

(Staphylococcus
aureus) 		PF00155
(Aminotran_1_2) 		4 ILE A 420
PHE A 363
PHE A 405
GLY A 392
 None
 0.99A 3em0B-2x5fA:
undetectable		 3em0B-2x5fA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xd3 MALTOSE/MALTODEXTRIN
-BINDING PROTEIN

(Streptococcus
pneumoniae) 		PF13416
(SBP_bac_8) 		4 ILE A 269
PHE A 196
PHE A 302
GLY A 271
 None
 1.08A 3em0B-2xd3A:
undetectable		 3em0B-2xd3A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zym SOLUTE-BINDING
PROTEIN

(Thermoactinomyces
vulgaris) 		PF13416
(SBP_bac_8) 		4 ILE A 246
PHE A 174
PHE A 278
GLY A 248
 None
 0.93A 3em0B-2zymA:
undetectable		 3em0B-2zymA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a24 ALPHA-GALACTOSIDASE

(Bacteroides
thetaiotaomicron) 		PF10566
(Glyco_hydro_97)
PF14508
(GH97_N)
PF14509
(GH97_C) 		4 ILE A 491
LYS A 483
TYR A 484
GLY A 578
 None
 0.82A 3em0B-3a24A:
2.1		 3em0B-3a24A:
12.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bs4 UNCHARACTERIZED
PROTEIN PH0321

(Pyrococcus
horikoshii) 		no annotation 4 ILE A  56
PHE A  38
TYR A  58
GLY A  90
 None
 1.11A 3em0B-3bs4A:
undetectable		 3em0B-3bs4A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgx PUTATIVE
NUCLEOTIDE-DIPHOSPHO
-SUGAR TRANSFERASE

(Desulfovibrio
alaskensis) 		PF09837
(DUF2064) 		4 PHE A 157
PHE A 147
LYS A 149
GLY A 101
 None
 0.94A 3em0B-3cgxA:
undetectable		 3em0B-3cgxA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3df7 PUTATIVE ATP-GRASP
SUPERFAMILY PROTEIN

(Archaeoglobus
fulgidus) 		PF02655
(ATP-grasp_3) 		4 ILE A 105
PHE A   9
PHE A   7
GLY A  99
 None
 1.08A 3em0B-3df7A:
undetectable		 3em0B-3df7A:
20.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3elz ILEAL BILE
ACID-BINDING PROTEIN

(Danio rerio) 		PF14651
(Lipocalin_7) 		4 ILE A  21
PHE A  79
TYR A  97
GLY A 116
 CHD  A 153 ( 4.1A)
CHD  A 153 ( 4.9A)
CHD  A 153 (-4.2A)
None
 0.50A 3em0B-3elzA:
23.6		 3em0B-3elzA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g8k LECTIN-RELATED NK
CELL RECEPTOR LY49L1

(Mus musculus) 		PF00059
(Lectin_C) 		4 ILE A 180
PHE A 147
PHE A 156
GLY A 201
 None
 1.03A 3em0B-3g8kA:
undetectable		 3em0B-3g8kA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h09 IMMUNOGLOBULIN A1
PROTEASE

(Haemophilus
influenzae) 		PF02395
(Peptidase_S6)
PF03212
(Pertactin) 		4 ILE A  72
PHE A  77
PHE A 293
GLY A 300
 None
 0.89A 3em0B-3h09A:
undetectable		 3em0B-3h09A:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hsk ASPARTATE-SEMIALDEHY
DE DEHYDROGENASE

(Candida
albicans) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 ILE A 364
PHE A  29
PHE A  82
GLY A 148
 None
 0.91A 3em0B-3hskA:
undetectable		 3em0B-3hskA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kd3 PHOSPHOSERINE
PHOSPHOHYDROLASE-LIK
E PROTEIN

(Francisella
tularensis) 		PF12710
(HAD) 		4 ILE A 100
PHE A 153
LYS A 149
GLY A 103
 None
 1.11A 3em0B-3kd3A:
undetectable		 3em0B-3kd3A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ln7 GLUTATHIONE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
GSHAB

(Pasteurella
multocida) 		PF02655
(ATP-grasp_3)
PF04262
(Glu_cys_ligase) 		4 ILE A 299
PHE A 286
TYR A 145
GLY A 142
 None
 1.07A 3em0B-3ln7A:
undetectable		 3em0B-3ln7A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n6z PUTATIVE
IMMUNOGLOBULIN A1
PROTEASE

(Bacteroides
ovatus) 		no annotation 4 ILE A 204
PHE A 120
PHE A 140
GLY A 206
 None
 1.11A 3em0B-3n6zA:
undetectable		 3em0B-3n6zA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3n9x PHOSPHOTRANSFERASE

(Plasmodium
berghei) 		PF00069
(Pkinase) 		4 ILE A 107
PHE A 102
PHE A  63
GLY A  40
 None
 1.01A 3em0B-3n9xA:
undetectable		 3em0B-3n9xA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nie MAP2 KINASE

(Plasmodium
falciparum) 		PF00069
(Pkinase) 		4 ILE A 109
PHE A 104
PHE A  65
GLY A  42
 None
None
None
ANP  A 430 (-3.9A)
 1.07A 3em0B-3nieA:
undetectable		 3em0B-3nieA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3omn CYTOCHROME C
OXIDASE, AA3 TYPE,
SUBUNIT I

(Rhodobacter
sphaeroides) 		PF00115
(COX1) 		4 ILE A 302
PHE A 457
PHE A 430
GLY A 296
 None
 0.72A 3em0B-3omnA:
undetectable		 3em0B-3omnA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ptk BETA-GLUCOSIDASE
OS4BGLU12

(Oryza sativa) 		PF00232
(Glyco_hydro_1) 		4 PHE A  15
PHE A  21
TYR A 439
GLY A 318
 None
 1.00A 3em0B-3ptkA:
undetectable		 3em0B-3ptkA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qgk UREASE SUBUNIT BETA
2

(Helicobacter
mustelae) 		PF00449
(Urease_alpha)
PF01979
(Amidohydro_1) 		4 ILE C 132
PHE C 138
PHE C 144
GLY C 151
 None
 1.05A 3em0B-3qgkC:
undetectable		 3em0B-3qgkC:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qty PHOSPHORIBOSYLAMINOI
MIDAZOLE (AIR)
SYNTHETASE

(Francisella
tularensis) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 ILE A 246
PHE A 317
LYS A 319
GLY A 243
 None
 1.12A 3em0B-3qtyA:
undetectable		 3em0B-3qtyA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sfz APOPTOTIC PEPTIDASE
ACTIVATING FACTOR 1

(Mus musculus) 		PF00400
(WD40)
PF00931
(NB-ARC)
PF12894
(ANAPC4_WD40) 		4 ILE A 327
PHE A 444
PHE A 350
LYS A 348
 None
 0.96A 3em0B-3sfzA:
2.6		 3em0B-3sfzA:
7.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wq4 BETA-PRIMEVEROSIDASE

(Camellia
sinensis) 		PF00232
(Glyco_hydro_1) 		4 PHE A  39
PHE A  45
TYR A 460
GLY A 341
 None
 1.03A 3em0B-3wq4A:
undetectable		 3em0B-3wq4A:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wzf ASPARTATE
AMINOTRANSFERASE,
CYTOPLASMIC

(Homo sapiens) 		PF00155
(Aminotran_1_2) 		4 ILE A 185
PHE A 243
PHE A 221
GLY A 115
 None
 0.97A 3em0B-3wzfA:
undetectable		 3em0B-3wzfA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dyx FERRITIN HEAVY CHAIN

(Homo sapiens) 		PF00210
(Ferritin) 		4 PHE A 170
PHE A  51
LYS A  53
TYR A  54
 None
 0.74A 3em0B-4dyxA:
undetectable		 3em0B-4dyxA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g9i HYDROGENASE
MATURATION PROTEIN
HYPF

(Thermococcus
kodakarensis) 		PF00708
(Acylphosphatase)
PF00814
(Peptidase_M22)
PF01300
(Sua5_yciO_yrdC)
PF07503
(zf-HYPF) 		4 ILE A 392
PHE A 444
PHE A 411
GLY A 752
 None
 1.00A 3em0B-4g9iA:
undetectable		 3em0B-4g9iA:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grx AMINOTRANSFERASE

(Paracoccus
denitrificans) 		PF00202
(Aminotran_3) 		4 PHE A 356
PHE A 438
LYS A 440
GLY A 411
 None
 0.89A 3em0B-4grxA:
undetectable		 3em0B-4grxA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ham LMO2241 PROTEIN

(Listeria
monocytogenes) 		PF00392
(GntR) 		4 ILE A  75
PHE A  41
PHE A   2
GLY A  27
 None
 1.11A 3em0B-4hamA:
undetectable		 3em0B-4hamA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i1u DEPHOSPHO-COA KINASE

(Burkholderia
vietnamiensis) 		PF01121
(CoaE) 		4 ILE A 108
PHE A 197
TYR A 194
GLY A 104
 None
 1.10A 3em0B-4i1uA:
undetectable		 3em0B-4i1uA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iit PHENYLACETATE-COA
OXYGENASE SUBUNIT
PAAC

(Klebsiella
pneumoniae) 		PF05138
(PaaA_PaaC) 		4 ILE C 187
PHE C  55
LYS C   5
TYR C  10
 None
 1.10A 3em0B-4iitC:
undetectable		 3em0B-4iitC:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j7m PROTEIN DOM3Z

(Mus musculus) 		PF08652
(RAI1) 		4 PHE A 306
PHE A 269
TYR A 270
GLY A 321
 None
 0.89A 3em0B-4j7mA:
undetectable		 3em0B-4j7mA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lqx TENA/THI-4
DOMAIN-CONTAINING
PROTEIN

(Sulfolobus
solfataricus) 		PF03070
(TENA_THI-4)
PF16293
(zf-C2H2_9) 		4 ILE A 179
PHE A 279
LYS A 281
TYR A 282
 None
UNL  A 402 ( 4.6A)
SO4  A 404 (-3.1A)
None
 1.02A 3em0B-4lqxA:
undetectable		 3em0B-4lqxA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4my0 GCN5-RELATED
N-ACETYLTRANSFERASE

(Kribbella
flavida) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		4 PHE A 293
PHE A 378
TYR A 349
GLY A 135
 None
 1.09A 3em0B-4my0A:
undetectable		 3em0B-4my0A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nfy D-3-PHOSPHOGLYCERATE
DEHYDROGENASE,
PUTATIVE

(Entamoeba
histolytica) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 ILE A 203
PHE A 257
TYR A 238
GLY A 210
 None
 0.90A 3em0B-4nfyA:
undetectable		 3em0B-4nfyA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ofn GLUTATHIONE
S-TRANSFERASE-1

(Necator
americanus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 PHE A 206
PHE A 106
TYR A 107
GLY A 115
 None
 0.99A 3em0B-4ofnA:
undetectable		 3em0B-4ofnA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4om9 SERINE PROTEASE PET

(Escherichia
coli) 		PF02395
(Peptidase_S6) 		4 ILE A 364
PHE A 336
PHE A 316
GLY A 367
 None
 1.10A 3em0B-4om9A:
undetectable		 3em0B-4om9A:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p1n ATG1 TMIT

(Kluyveromyces
marxianus) 		PF12063
(DUF3543) 		4 ILE A 654
PHE A 720
PHE A 593
LYS A 592
 None
 1.04A 3em0B-4p1nA:
undetectable		 3em0B-4p1nA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4psw HISTONE
ACETYLTRANSFERASE
TYPE B CATALYTIC
SUBUNIT

(Saccharomyces
cerevisiae) 		PF00583
(Acetyltransf_1)
PF10394
(Hat1_N) 		4 ILE A 188
PHE A  31
PHE A 160
GLY A 232
 None
None
None
COA  A 401 (-3.3A)
 0.86A 3em0B-4pswA:
1.8		 3em0B-4pswA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qb5 GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Rhodoferax
ferrireducens) 		PF00903
(Glyoxalase) 		4 ILE A  28
PHE A  18
LYS A  16
GLY A  31
 None
 1.06A 3em0B-4qb5A:
undetectable		 3em0B-4qb5A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlj BETA-GLUCOSIDASE 7

(Oryza sativa) 		PF00232
(Glyco_hydro_1) 		4 PHE A  15
PHE A  21
TYR A 430
GLY A 311
 None
 1.00A 3em0B-4qljA:
undetectable		 3em0B-4qljA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r1i AMINOBENZOYL-GLUTAMA
TE TRANSPORTER

(Neisseria
gonorrhoeae) 		PF03806
(ABG_transport) 		4 ILE A 108
PHE A 188
PHE A 280
GLY A 331
 None
 0.97A 3em0B-4r1iA:
undetectable		 3em0B-4r1iA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4re2 BETA-MANNOSIDASE/BET
A-GLUCOSIDASE

(Oryza sativa) 		PF00232
(Glyco_hydro_1) 		4 PHE A  18
PHE A  24
TYR A 433
GLY A 314
 None
 1.12A 3em0B-4re2A:
undetectable		 3em0B-4re2A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ux3 STRUCTURAL
MAINTENANCE OF
CHROMOSOMES PROTEIN
3

(Saccharomyces
cerevisiae) 		PF02463
(SMC_N) 		4 ILE A1206
PHE A  11
LYS A   9
TYR A  14
 None
 1.12A 3em0B-4ux3A:
undetectable		 3em0B-4ux3A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wer DIACYLGLYCEROL
KINASE CATALYTIC
DOMAIN PROTEIN

(Enterococcus
faecalis) 		PF00781
(DAGK_cat) 		4 ILE A  74
PHE A  62
PHE A  89
GLY A  68
 None
None
None
AMP  A 401 (-3.4A)
 1.01A 3em0B-4werA:
0.7		 3em0B-4werA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wql 2''-AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE

(Klebsiella
pneumoniae) 		PF10706
(Aminoglyc_resit) 		4 ILE A  45
PHE A  76
PHE A  49
GLY A  27
 None
None
None
GOL  A 213 (-3.1A)
 1.10A 3em0B-4wqlA:
undetectable		 3em0B-4wqlA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xi0 MAGNETOSOME PROTEIN
MAMA

(Desulfovibrio
magneticus) 		PF07719
(TPR_2)
PF13432
(TPR_16) 		4 ILE A 165
PHE A 202
PHE A 187
GLY A 152
 None
 1.07A 3em0B-4xi0A:
undetectable		 3em0B-4xi0A:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zoy SQT1

(Chaetomium
thermophilum) 		PF00400
(WD40) 		4 ILE A 142
PHE A 147
PHE A 180
GLY A 137
 None
 1.07A 3em0B-4zoyA:
undetectable		 3em0B-4zoyA:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c8s GUANINE-N7
METHYLTRANSFERASE

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF06471
(NSP11) 		4 PHE B  60
PHE B   8
LYS B   9
GLY B 102
 None
 1.08A 3em0B-5c8sB:
undetectable		 3em0B-5c8sB:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dm7 50S RIBOSOMAL
PROTEIN L27

(Deinococcus
radiodurans) 		PF01016
(Ribosomal_L27) 		4 ILE T  36
PHE T  69
PHE T  45
GLY T  54
 A  X2333 ( 3.9A)
C  X 869 ( 3.5A)
None
C  X2343 ( 3.2A)
 0.96A 3em0B-5dm7T:
undetectable		 3em0B-5dm7T:
25.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ei0 SERPIN A12

(Homo sapiens) 		PF00079
(Serpin) 		4 ILE A 341
PHE A  83
PHE A 332
GLY A 336
 None
 1.09A 3em0B-5ei0A:
1.1		 3em0B-5ei0A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey5 LBCATS-A

(synthetic
construct) 		PF00290
(Trp_syntA) 		4 PHE A 114
PHE A  82
LYS A  80
GLY A  75
 None
 0.89A 3em0B-5ey5A:
undetectable		 3em0B-5ey5A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fa1 PUTATIVE N-ACETYL
GLUCOSAMINYL
TRANSFERASE

(Raoultella
terrigena) 		PF05159
(Capsule_synth) 		4 PHE A   5
PHE A 105
TYR A   9
GLY A  13
 None
 1.07A 3em0B-5fa1A:
undetectable		 3em0B-5fa1A:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h9f CRISPR SYSTEM
CASCADE SUBUNIT CASA

(Escherichia
coli) 		PF09481
(CRISPR_Cse1) 		4 ILE A 146
PHE A 233
PHE A  91
GLY A 141
 None
 0.68A 3em0B-5h9fA:
undetectable		 3em0B-5h9fA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5htv PUTATIVE XYLULOSE
KINASE

(Arabidopsis
thaliana) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ILE A 364
PHE A 356
PHE A 303
GLY A 392
 None
None
None
ANP  A 501 ( 3.9A)
 1.02A 3em0B-5htvA:
undetectable		 3em0B-5htvA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mjs TUBULIN BETA CHAIN

(Schizosaccharomyces
pombe) 		no annotation 4 ILE A 100
PHE A 384
TYR A 183
GLY A 141
 None
None
None
GDP  A 500 (-3.1A)
 0.98A 3em0B-5mjsA:
undetectable		 3em0B-5mjsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mlc 50S RIBOSOMAL
PROTEIN L27,
CHLOROPLASTIC

(Spinacia
oleracea) 		PF01016
(Ribosomal_L27) 		4 ILE X  92
PHE X 125
PHE X 101
GLY X 110
 A  A2371 ( 3.9A)
G  A 867 ( 4.0A)
G  A 867 ( 4.6A)
G  A2382 ( 3.9A)
 1.12A 3em0B-5mlcX:
undetectable		 3em0B-5mlcX:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mqp GLYCOSIDE HYDROLASE
BT_1002

(Bacteroides
thetaiotaomicron) 		no annotation 4 ILE A  24
PHE A 314
PHE A 319
GLY A  71
 None
 1.02A 3em0B-5mqpA:
undetectable		 3em0B-5mqpA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n94 CG9323, ISOFORM A

(Drosophila
melanogaster) 		no annotation 4 ILE A  52
LYS A 876
TYR A 866
GLY A  55
 None
 0.82A 3em0B-5n94A:
undetectable		 3em0B-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nva PUTATIVE
SODIUM:SOLUTE
SYMPORTER

(Proteus
mirabilis) 		no annotation 4 ILE A 464
PHE A 458
TYR A 461
GLY A 416
 None
 1.07A 3em0B-5nvaA:
undetectable		 3em0B-5nvaA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oev GLUTATHIONE
SYNTHETASE-LIKE
EFFECTOR 22
(GPA-GSS22-APO)

(Globodera
pallida) 		no annotation 4 ILE A 295
PHE A 212
PHE A 214
GLY A 251
 None
 0.88A 3em0B-5oevA:
undetectable		 3em0B-5oevA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tcb PELA

(Pseudomonas
aeruginosa) 		PF03537
(Glyco_hydro_114) 		4 ILE A 220
PHE A 197
PHE A  54
GLY A 223
 None
 1.10A 3em0B-5tcbA:
undetectable		 3em0B-5tcbA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5trv DENOVO NTF2

(synthetic
construct) 		PF12680
(SnoaL_2) 		4 ILE A 106
PHE A  92
LYS A  35
GLY A  37
 None
 1.04A 3em0B-5trvA:
undetectable		 3em0B-5trvA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xoh BERGAPTOL
O-METHYLTRANSFERASE

(Peucedanum
praeruptorum) 		no annotation 4 PHE A 167
PHE A 149
TYR A 319
GLY A 323
 None
None
8B6  A 402 ( 4.9A)
None
 1.07A 3em0B-5xohA:
undetectable		 3em0B-5xohA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6all FE(3+)-CITRATE-BINDI
NG PROTEIN YFMC

(Bacillus
anthracis) 		PF01497
(Peripla_BP_2) 		4 ILE A 302
PHE A 182
PHE A 151
GLY A 244
 None
 1.04A 3em0B-6allA:
undetectable		 3em0B-6allA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bme TRUNCATED HEMOGLOBIN
4

(Chlamydomonas
reinhardtii) 		no annotation 4 ILE A 135
PHE A  80
PHE A  51
GLY A 129
 None
HEM  A 201 (-4.3A)
None
None
 0.83A 3em0B-6bmeA:
undetectable		 3em0B-6bmeA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c49 ALCOHOL
DEHYDROGENASE

(Acinetobacter
baumannii) 		no annotation 4 ILE A 186
PHE A 233
PHE A 199
GLY A 179
 None
None
None
SO4  A 407 (-3.3A)
 0.91A 3em0B-6c49A:
undetectable		 3em0B-6c49A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4g ASPARTIC PROTEASE
PM5

(Plasmodium
vivax) 		no annotation 4 ILE A 229
PHE A 202
TYR A  50
GLY A 226
 None
 1.09A 3em0B-6c4gA:
undetectable		 3em0B-6c4gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f74 ALCOHOL OXIDASE

(Thermothelomyces
thermophila) 		no annotation 4 ILE A 265
LYS A 567
TYR A 570
GLY A 293
 None
GOL  A 606 (-4.9A)
None
None
 0.98A 3em0B-6f74A:
undetectable		 3em0B-6f74A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fai SERINE/THREONINE-PRO
TEIN KINASE RIO2

(Saccharomyces
cerevisiae) 		no annotation 4 ILE l 235
PHE l 174
LYS l 175
GLY l 248
 None
 1.09A 3em0B-6fail:
undetectable		 3em0B-6fail:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fls -

(-) 		no annotation 4 ILE A  42
PHE A  72
PHE A  77
GLY A  39
 None
 1.08A 3em0B-6flsA:
undetectable		 3em0B-6flsA:
undetectable