SIMILAR PATTERNS OF AMINO ACIDS FOR 3EM0_B_CHDB152

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bdb CIS-BIPHENYL-2,3-DIH
YDRODIOL-2,3-DEHYDRO
GENASE

(Pseudomonas sp.) 		PF00106
(adh_short) 		4 PRO A 223
TYR A 232
VAL A 182
GLY A 183
 None
 0.91A 3em0B-1bdbA:
undetectable		 3em0B-1bdbA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3r HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN)

(Aquifex
aeolicus) 		PF00850
(Hist_deacetyl) 		4 ILE A  88
TYR A  17
PRO A  18
GLY A 140
 None
None
None
TSN  A 502 ( 3.9A)
 0.89A 3em0B-1c3rA:
0.0		 3em0B-1c3rA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ekb ENTEROPEPTIDASE

(Bos taurus) 		PF00089
(Trypsin) 		4 ILE B 238
ASN B 100
VAL B 212
GLY B 211
 None
 0.95A 3em0B-1ekbB:
0.0		 3em0B-1ekbB:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1elv COMPLEMENT C1S
COMPONENT

(Homo sapiens) 		PF00084
(Sushi)
PF00089
(Trypsin) 		4 ILE A 602
TYR A 633
VAL A 623
GLY A 550
 None
 0.93A 3em0B-1elvA:
0.0		 3em0B-1elvA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ep5 CAPSID PROTEIN C

(Venezuelan
equine
encephalitis
virus) 		no annotation 4 ILE B 157
PRO B 181
ASN B 183
VAL B 142
 None
 0.95A 3em0B-1ep5B:
0.3		 3em0B-1ep5B:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fno PEPTIDASE T

(Salmonella
enterica) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ILE A 215
ASN A 233
VAL A 301
GLY A 302
 None
 0.68A 3em0B-1fnoA:
0.0		 3em0B-1fnoA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g71 DNA PRIMASE

(Pyrococcus
furiosus) 		PF01896
(DNA_primase_S) 		4 PRO A 320
ASN A 319
HIS A 323
VAL A 308
 None
 0.78A 3em0B-1g71A:
undetectable		 3em0B-1g71A:
17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1geu GLUTATHIONE
REDUCTASE

(Escherichia
coli) 		PF02852
(Pyr_redox_dim)
PF07992
(Pyr_redox_2) 		4 ILE A 270
ASN A 280
VAL A 277
GLY A 276
 FAD  A 451 (-4.4A)
None
None
None
 0.95A 3em0B-1geuA:
0.0		 3em0B-1geuA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1icp 12-OXOPHYTODIENOATE
REDUCTASE 1

(Solanum
lycopersicum) 		PF00724
(Oxidored_FMN) 		4 ILE A  14
TYR A 329
ASN A 336
VAL A  31
 None
 0.89A 3em0B-1icpA:
0.0		 3em0B-1icpA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ko7 HPR
KINASE/PHOSPHATASE

(Staphylococcus
xylosus) 		PF02603
(Hpr_kinase_N)
PF07475
(Hpr_kinase_C) 		4 ILE A 273
ASN A 283
VAL A 145
GLY A 146
 None
 0.83A 3em0B-1ko7A:
undetectable		 3em0B-1ko7A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgj PEROXIDASE N

(Arabidopsis
thaliana) 		PF00141
(peroxidase) 		4 PRO A  12
ASN A  13
VAL A  91
GLY A  90
 None
 0.61A 3em0B-1qgjA:
undetectable		 3em0B-1qgjA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rr9 ATP-DEPENDENT
PROTEASE LA

(Escherichia
coli) 		PF05362
(Lon_C) 		4 ILE A 747
PRO A 759
HIS A 758
VAL A 734
 None
 0.87A 3em0B-1rr9A:
undetectable		 3em0B-1rr9A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1sk4 PEPTIDOGLYCAN
RECOGNITION PROTEIN
I-ALPHA

(Homo sapiens) 		PF01510
(Amidase_2) 		4 ILE A 275
PRO A 179
ASN A 180
GLY A 257
 None
 0.92A 3em0B-1sk4A:
undetectable		 3em0B-1sk4A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t9k PROBABLE
METHYLTHIORIBOSE-1-P
HOSPHATE ISOMERASE

(Thermotoga
maritima) 		PF01008
(IF-2B) 		4 ILE A 319
HIS A 153
VAL A 231
GLY A 232
 None
 0.84A 3em0B-1t9kA:
undetectable		 3em0B-1t9kA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v4g GLUTAMATE--CYSTEINE
LIGASE

(Escherichia
coli) 		PF04262
(Glu_cys_ligase) 		4 ILE A   2
PRO A   3
VAL A 193
GLY A 191
 None
 0.83A 3em0B-1v4gA:
undetectable		 3em0B-1v4gA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vic 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE

(Haemophilus
influenzae) 		PF02348
(CTP_transf_3) 		4 ILE A 104
PRO A 105
ASN A 115
GLY A 187
 None
 0.93A 3em0B-1vicA:
undetectable		 3em0B-1vicA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wdw TRYPTOPHAN SYNTHASE
BETA CHAIN 1

(Pyrococcus
furiosus) 		PF00291
(PALP) 		4 ILE B 165
PRO B 302
VAL B 187
GLY B 188
 None
 0.92A 3em0B-1wdwB:
undetectable		 3em0B-1wdwB:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wyt GLYCINE
DEHYDROGENASE
SUBUNIT 2
(P-PROTEIN)

(Thermus
thermophilus) 		PF02347
(GDC-P) 		4 PRO B 381
PRO B  70
HIS B 400
GLY B 393
 None
 0.93A 3em0B-1wytB:
undetectable		 3em0B-1wytB:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yyc PUTATIVE LATE
EMBRYOGENESIS
ABUNDANT PROTEIN

(Arabidopsis
thaliana) 		PF03168
(LEA_2) 		4 ILE A 137
TYR A  64
VAL A  62
GLY A  61
 None
 0.77A 3em0B-1yycA:
undetectable		 3em0B-1yycA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ca4 SULFITE:CYTOCHROME C
OXIDOREDUCTASE
SUBUNIT A

(Starkeya
novella) 		PF00174
(Oxidored_molyb)
PF03404
(Mo-co_dimer) 		4 ILE A  61
PRO A  62
TYR A  18
PRO A  19
 None
 0.90A 3em0B-2ca4A:
undetectable		 3em0B-2ca4A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e0w GAMMA-GLUTAMYLTRANSP
EPTIDASE

(Escherichia
coli) 		PF01019
(G_glu_transpept) 		4 PRO A 200
ASN A 201
HIS A 202
GLY A 415
 None
 0.60A 3em0B-2e0wA:
0.3		 3em0B-2e0wA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g3n ALPHA-GLUCOSIDASE

(Sulfolobus
solfataricus) 		PF01055
(Glyco_hydro_31)
PF13802
(Gal_mutarotas_2) 		4 ILE A 608
PRO A 609
VAL A 552
GLY A 553
 None
 0.77A 3em0B-2g3nA:
undetectable		 3em0B-2g3nA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gpj SIDEROPHORE-INTERACT
ING PROTEIN

(Shewanella
putrefaciens) 		PF04954
(SIP)
PF08021
(FAD_binding_9) 		4 ILE A 107
ASN A 135
VAL A 160
GLY A 139
 None
None
None
CA  A 252 ( 4.6A)
 0.83A 3em0B-2gpjA:
undetectable		 3em0B-2gpjA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h8r HEPATOCYTE NUCLEAR
FACTOR 1-BETA

(Homo sapiens) 		PF00046
(Homeobox)
PF04814
(HNF-1_N) 		4 ILE A 179
ASN A 269
VAL A 278
GLY A 277
 None
 0.72A 3em0B-2h8rA:
undetectable		 3em0B-2h8rA:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i7x PROTEIN CFT2

(Saccharomyces
cerevisiae) 		PF16661
(Lactamase_B_6) 		4 ILE A 187
PRO A  92
ASN A  95
GLY A 252
 None
 0.87A 3em0B-2i7xA:
undetectable		 3em0B-2i7xA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2kkn UNCHARACTERIZED
PROTEIN

(Thermotoga
maritima) 		PF12850
(Metallophos_2) 		4 ILE A  84
HIS A  88
VAL A  58
GLY A  57
 None
 0.89A 3em0B-2kknA:
undetectable		 3em0B-2kknA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ksw ORYCTIN

(Oryctes
rhinoceros) 		no annotation 4 PRO A  45
ASN A  46
HIS A  47
GLY A   4
 None
 0.84A 3em0B-2kswA:
undetectable		 3em0B-2kswA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2n9v DERMONECROTIC TOXIN

(Pasteurella
multocida) 		PF11647
(MLD) 		4 ASN A  36
HIS A  35
VAL A   3
GLY A   2
 None
 0.68A 3em0B-2n9vA:
undetectable		 3em0B-2n9vA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qw8 EUGENOL SYNTHASE 1

(Ocimum
basilicum) 		PF05368
(NmrA) 		4 ILE A  19
TYR A 210
ASN A 215
GLY A 113
 NAP  A 401 (-4.4A)
None
None
NO3  A 902 ( 3.3A)
 0.77A 3em0B-2qw8A:
undetectable		 3em0B-2qw8A:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wf7 BETA-PHOSPHOGLUCOMUT
ASE

(Lactococcus
lactis) 		PF13419
(HAD_2) 		4 TYR A 207
HIS A 206
VAL A 188
GLY A 189
 None
 0.82A 3em0B-2wf7A:
undetectable		 3em0B-2wf7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zl5 58 KD CAPSID PROTEIN

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		4 ILE A 392
PRO A 393
HIS A 404
GLY A 278
 None
ACT  A 521 (-4.6A)
None
None
 0.92A 3em0B-2zl5A:
undetectable		 3em0B-2zl5A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zsj THREONINE SYNTHASE

(Aquifex
aeolicus) 		PF00291
(PALP) 		4 TYR A  53
PRO A  32
VAL A 286
GLY A 285
 None
 0.92A 3em0B-2zsjA:
undetectable		 3em0B-2zsjA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bn0 30S RIBOSOMAL
PROTEIN S16

(Aquifex
aeolicus) 		PF00886
(Ribosomal_S16) 		4 ILE A   5
ASN A  75
HIS A  76
GLY A  38
 None
 0.78A 3em0B-3bn0A:
undetectable		 3em0B-3bn0A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bvh FIBRINOGEN GAMMA
CHAIN

(Homo sapiens) 		PF00147
(Fibrinogen_C)
PF08702
(Fib_alpha) 		4 PRO C 360
ASN C 361
VAL C 347
GLY C 346
 None
 0.90A 3em0B-3bvhC:
undetectable		 3em0B-3bvhC:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1o EUGENOL SYNTHASE

(Clarkia breweri) 		PF05368
(NmrA) 		4 ILE A  13
TYR A 212
ASN A 217
GLY A 112
 NAP  A 401 (-4.3A)
None
None
NAP  A 401 ( 3.7A)
 0.81A 3em0B-3c1oA:
undetectable		 3em0B-3c1oA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cj1 ECTONUCLEOSIDE
TRIPHOSPHATE
DIPHOSPHOHYDROLASE 2

(Rattus
norvegicus) 		PF01150
(GDA1_CD39) 		4 ILE A 448
TYR A 233
HIS A 232
GLY A 230
 None
 0.92A 3em0B-3cj1A:
undetectable		 3em0B-3cj1A:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3col PUTATIVE
TRANSCRIPTION
REGULATOR

(Lactobacillus
plantarum) 		PF00440
(TetR_N) 		4 ILE A 110
ASN A  50
VAL A  28
GLY A  27
 None
 0.84A 3em0B-3colA:
undetectable		 3em0B-3colA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dh0 SAM DEPENDENT
METHYLTRANSFERASE

(Aquifex
aeolicus) 		PF13847
(Methyltransf_31) 		4 ILE A 141
ASN A  98
VAL A  44
GLY A  45
 None
None
SAM  A 220 ( 4.8A)
SAM  A 220 (-3.5A)
 0.89A 3em0B-3dh0A:
undetectable		 3em0B-3dh0A:
18.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3elz ILEAL BILE
ACID-BINDING PROTEIN

(Danio rerio) 		PF14651
(Lipocalin_7) 		5 TYR A  53
PRO A  54
ASN A  55
VAL A  74
GLY A  75
 CHD  A 151 (-4.5A)
None
None
CHD  A 200 (-3.7A)
CHD  A 200 (-3.4A)
 0.64A 3em0B-3elzA:
23.6		 3em0B-3elzA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ewm UNCHARACTERIZED
SUGAR KINASE PH1459

(Pyrococcus
horikoshii) 		PF00294
(PfkB) 		4 ILE A 117
PRO A 139
ASN A 138
GLY A   8
 None
 0.93A 3em0B-3ewmA:
undetectable		 3em0B-3ewmA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f1s VITAMIN K-DEPENDENT
PROTEIN Z

(Homo sapiens) 		PF00089
(Trypsin)
PF14670
(FXa_inhibition) 		4 ILE B 168
ASN B 220
VAL B 330
GLY B 329
 None
 0.95A 3em0B-3f1sB:
undetectable		 3em0B-3f1sB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fac PUTATIVE
UNCHARACTERIZED
PROTEIN

(Rhodobacter
sphaeroides) 		PF04828
(GFA) 		4 ILE A  75
PRO A 100
ASN A  99
GLY A   3
 None
 0.75A 3em0B-3facA:
undetectable		 3em0B-3facA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fq3 INORGANIC
PYROPHOSPHATASE:BACT
ERIAL/ARCHAEAL
INORGANIC
PYROPHOSPHATASE

(Brucella
abortus) 		PF00719
(Pyrophosphatase) 		4 ILE A 166
PRO A  13
VAL A  93
GLY A  92
 None
 0.91A 3em0B-3fq3A:
undetectable		 3em0B-3fq3A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hmb N-ACETYLMURAMOYL-L-A
LANINE AMIDASE XLYA

(Bacillus
subtilis) 		PF01510
(Amidase_2) 		4 ILE A 113
PRO A 139
HIS A 130
GLY A  91
 None
None
ZN  A 155 (-3.3A)
None
 0.95A 3em0B-3hmbA:
undetectable		 3em0B-3hmbA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hwc CHLOROPHENOL-4-MONOO
XYGENASE COMPONENT 2

(Burkholderia
cepacia) 		PF03241
(HpaB)
PF11794
(HpaB_N) 		4 ILE A3263
PRO A3264
VAL A3227
GLY A3226
 None
 0.69A 3em0B-3hwcA:
undetectable		 3em0B-3hwcA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4q APC40078

(Oleispira
antarctica) 		PF00719
(Pyrophosphatase) 		4 ILE A 166
PRO A  13
VAL A  93
GLY A  92
 None
 0.83A 3em0B-3i4qA:
undetectable		 3em0B-3i4qA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3imh GALACTOSE-1-EPIMERAS
E

(Lactobacillus
acidophilus) 		PF01263
(Aldose_epim) 		4 ILE A 311
TYR A 136
PRO A 137
GLY A  70
 None
 0.92A 3em0B-3imhA:
1.9		 3em0B-3imhA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb4 VP1

(Parechovirus B) 		no annotation 4 ILE A 132
HIS A 110
VAL A  94
GLY A  95
 None
 0.84A 3em0B-3jb4A:
undetectable		 3em0B-3jb4A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jz4 SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE
[NADP+]

(Escherichia
coli) 		PF00171
(Aldedh) 		4 ILE A  14
PRO A 180
VAL A 215
GLY A  45
 None
 0.90A 3em0B-3jz4A:
undetectable		 3em0B-3jz4A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l2k EHPF

(Pantoea
agglomerans) 		PF00501
(AMP-binding) 		4 ILE A 139
PRO A 140
VAL A 270
GLY A 263
 None
 0.76A 3em0B-3l2kA:
undetectable		 3em0B-3l2kA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lo0 INORGANIC
PYROPHOSPHATASE

(Ehrlichia
chaffeensis) 		PF00719
(Pyrophosphatase) 		4 ILE A 166
PRO A  13
VAL A  93
GLY A  92
 None
 0.91A 3em0B-3lo0A:
undetectable		 3em0B-3lo0A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mi6 ALPHA-GALACTOSIDASE

(Lactobacillus
brevis) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		4 ILE A 297
TYR A 567
PRO A 568
GLY A 537
 None
 0.95A 3em0B-3mi6A:
1.9		 3em0B-3mi6A:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q6v BETA-LACTAMASE

(Serratia
fonticola) 		PF00753
(Lactamase_B) 		4 ILE A 136
PRO A 172
PRO A  89
GLY A  84
 None
 0.72A 3em0B-3q6vA:
undetectable		 3em0B-3q6vA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qi7 PUTATIVE
TRANSCRIPTIONAL
REGULATOR

(Clostridioides
difficile) 		PF12683
(DUF3798) 		4 ILE A 204
ASN A 219
VAL A 256
GLY A 255
 None
 0.94A 3em0B-3qi7A:
undetectable		 3em0B-3qi7A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r89 OROTIDINE
5'-PHOSPHATE
DECARBOXYLASE

(Anaerococcus
prevotii) 		PF00215
(OMPdecase) 		4 ILE A 221
PRO A 222
HIS A 203
VAL A 207
 None
 0.86A 3em0B-3r89A:
undetectable		 3em0B-3r89A:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t4c 2-DEHYDRO-3-DEOXYPHO
SPHOOCTONATE
ALDOLASE 1

(Burkholderia
ambifaria) 		PF00793
(DAHP_synth_1) 		4 ILE A  39
PRO A 243
ASN A 242
GLY A  19
 None
 0.92A 3em0B-3t4cA:
undetectable		 3em0B-3t4cA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ufc PUTATIVE
UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF01881
(Cas_Cas6) 		4 ILE X  55
ASN X  13
VAL X 105
GLY X 106
 None
 0.67A 3em0B-3ufcX:
undetectable		 3em0B-3ufcX:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0i VOLTAGE-SENSOR
CONTAINING
PHOSPHATASE

(Ciona
intestinalis) 		PF00782
(DSPc)
PF10409
(PTEN_C2) 		4 PRO A 551
ASN A 550
VAL A 452
GLY A 453
 None
 0.92A 3em0B-3v0iA:
undetectable		 3em0B-3v0iA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wz2 UNCHARACTERIZED
PROTEIN

(Pyrococcus
furiosus) 		PF09754
(PAC2) 		4 ILE A  54
PRO A  55
TYR A  23
PRO A  24
 None
 0.94A 3em0B-3wz2A:
undetectable		 3em0B-3wz2A:
26.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bc5 XYLULOSE KINASE

(Homo sapiens) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ILE A 463
ASN A  30
VAL A 471
GLY A 472
 None
 0.80A 3em0B-4bc5A:
undetectable		 3em0B-4bc5A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bh6 APC/C ACTIVATOR
PROTEIN CDH1

(Saccharomyces
cerevisiae) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 PRO A 419
HIS A 364
VAL A 388
GLY A 404
 None
 0.85A 3em0B-4bh6A:
undetectable		 3em0B-4bh6A:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cuo BANYAN PEROXIDASE

(Ficus
benghalensis) 		PF00141
(peroxidase) 		4 PRO A  12
ASN A  13
VAL A  94
GLY A  93
 None
 0.69A 3em0B-4cuoA:
undetectable		 3em0B-4cuoA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cvq GLUTAMATE-PYRUVATE
AMINOTRANSFERASE
ALAA

(Escherichia
coli) 		PF00155
(Aminotran_1_2) 		4 ILE A  54
PRO A  51
HIS A  84
GLY A 237
 None
 0.78A 3em0B-4cvqA:
undetectable		 3em0B-4cvqA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hl4 TBC1 DOMAIN FAMILY
MEMBER 20

(Homo sapiens) 		PF00566
(RabGAP-TBC) 		4 ILE A 196
HIS A 276
VAL A 212
GLY A 213
 None
ACT  A 402 (-4.0A)
None
None
 0.82A 3em0B-4hl4A:
undetectable		 3em0B-4hl4A:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hyq PHOSPHOLIPASE A1

(Streptomyces
albidoflavus) 		PF13472
(Lipase_GDSL_2) 		4 ILE A 189
PRO A 143
PRO A  36
GLY A 226
 None
 0.70A 3em0B-4hyqA:
undetectable		 3em0B-4hyqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ixu ARGINASE-2,
MITOCHONDRIAL

(Homo sapiens) 		PF00491
(Arginase) 		4 ILE A  86
PRO A 151
VAL A  92
GLY A  93
 None
 0.92A 3em0B-4ixuA:
undetectable		 3em0B-4ixuA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4j9w PROLINE RACEMASE
FAMILY PROTEIN

(Pseudomonas
protegens) 		PF05544
(Pro_racemase) 		4 PRO A 115
PRO A 227
VAL A  60
GLY A  61
 None
 0.75A 3em0B-4j9wA:
undetectable		 3em0B-4j9wA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oue PUTATIVE LIPOPROTEIN

(Bacteroides
thetaiotaomicron) 		PF00754
(F5_F8_type_C)
PF01120
(Alpha_L_fucos) 		4 ILE A 341
ASN A  41
VAL A 308
GLY A 309
 None
 0.55A 3em0B-4oueA:
undetectable		 3em0B-4oueA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p3i P DOMAIN OF VP1

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		4 ILE A 400
PRO A 401
HIS A 412
GLY A 279
 None
 0.88A 3em0B-4p3iA:
undetectable		 3em0B-4p3iA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pdx PUTATIVE
ALKYL/ARYL-SULFATASE
YJCS

(Escherichia
coli) 		PF00753
(Lactamase_B)
PF14863
(Alkyl_sulf_dimr)
PF14864
(Alkyl_sulf_C) 		4 ILE A 192
TYR A 178
HIS A 185
GLY A 187
 None
 0.86A 3em0B-4pdxA:
undetectable		 3em0B-4pdxA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pvi GH62 HYDROLASE

(Mycothermus
thermophilus) 		PF03664
(Glyco_hydro_62) 		4 PRO A 142
TYR A 126
PRO A 111
GLY A 104
 None
 0.95A 3em0B-4pviA:
2.6		 3em0B-4pviA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qi7 CELLOBIOSE
DEHYDROGENASE

(Neurospora
crassa) 		PF00732
(GMC_oxred_N)
PF00734
(CBM_1)
PF05199
(GMC_oxred_C)
PF16010
(CDH-cyt) 		4 ILE A 752
PRO A 748
ASN A 526
GLY A 481
 FAD  A 902 (-4.6A)
FAD  A 902 (-4.4A)
None
FAD  A 902 (-3.4A)
 0.91A 3em0B-4qi7A:
1.6		 3em0B-4qi7A:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlo HOMOSERINE
O-ACETYLTRANSFERASE

(Staphylococcus
aureus) 		PF00561
(Abhydrolase_1) 		4 ILE A  65
ASN A  49
HIS A  44
GLY A 129
 None
 0.88A 3em0B-4qloA:
undetectable		 3em0B-4qloA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wrn MALTOSE-BINDING
PERIPLASMIC
PROTEIN,UROMODULIN

(Escherichia
coli;
Homo sapiens) 		PF00100
(Zona_pellucida)
PF13416
(SBP_bac_8) 		4 ILE A 623
ASN A 700
VAL A 587
GLY A 588
 None
 0.84A 3em0B-4wrnA:
undetectable		 3em0B-4wrnA:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xf7 CARBOHYDRATE/PYRIMID
INE KINASE, PFKB
FAMILY

(Thermococcus
kodakarensis) 		no annotation 4 ILE A 152
PRO A 111
ASN A 110
VAL A 121
 None
 0.95A 3em0B-4xf7A:
undetectable		 3em0B-4xf7A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xq2 CALE6

(Micromonospora
echinospora) 		PF01053
(Cys_Met_Meta_PP) 		4 PRO A 125
PRO A 283
HIS A 285
VAL A 287
 None
 0.86A 3em0B-4xq2A:
undetectable		 3em0B-4xq2A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xru HEN1

(Capnocytophaga
gingivalis) 		no annotation 4 ILE C 202
PRO C 203
HIS C 143
GLY C 158
 None
 0.75A 3em0B-4xruC:
undetectable		 3em0B-4xruC:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yff SERINE/THREONINE-PRO
TEIN KINASE TNNI3K

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 ILE A 489
ASN A 484
VAL A 525
GLY A 526
 None
 0.92A 3em0B-4yffA:
undetectable		 3em0B-4yffA:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynu GLUCOSE OXIDASE,
PUTATIVE

(Aspergillus
flavus) 		PF00732
(GMC_oxred_N)
PF05199
(GMC_oxred_C) 		4 ILE A 427
ASN A 371
HIS A 373
GLY A 290
 None
 0.89A 3em0B-4ynuA:
0.9		 3em0B-4ynuA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zoh PUTATIVE
OXIDOREDUCTASE
IRON-SULFUR SUBUNIT

(Sulfurisphaera
tokodaii) 		PF00111
(Fer2)
PF01799
(Fer2_2) 		4 ILE C  94
PRO C  93
PRO C 127
ASN C 126
 None
 0.88A 3em0B-4zohC:
undetectable		 3em0B-4zohC:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zw2 VOLTAGE-DEPENDENT
L-TYPE CALCIUM
CHANNEL SUBUNIT
BETA-1,VOLTAGE-DEPEN
DENT L-TYPE CALCIUM
CHANNEL SUBUNIT
BETA-1

(Mus musculus) 		PF00625
(Guanylate_kin)
PF12052
(VGCC_beta4Aa_N) 		4 ILE A 222
PRO A 200
ASN A 199
HIS A 203
 None
 0.79A 3em0B-4zw2A:
undetectable		 3em0B-4zw2A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a31 THE
ANAPHASE-PROMOTING
COMPLEX CHAIN R

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 PRO R 343
HIS R 288
VAL R 312
GLY R 328
 None
 0.82A 3em0B-5a31R:
undetectable		 3em0B-5a31R:
15.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ab4 SCP2-THIOLASE LIKE
PROTEIN

(Trypanosoma
brucei) 		no annotation 4 ILE A 344
PRO A 343
VAL A 311
GLY A 312
 None
 0.81A 3em0B-5ab4A:
undetectable		 3em0B-5ab4A:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ah1 TRIACYLGLYCEROL
LIPASE

(Clostridium
botulinum) 		no annotation 4 ILE A  30
PRO A  31
VAL A 386
GLY A 385
 None
 0.78A 3em0B-5ah1A:
undetectable		 3em0B-5ah1A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5an9 60S RIBOSOMAL
PROTEIN L3

(Dictyostelium
discoideum) 		PF00297
(Ribosomal_L3) 		4 ILE A 350
PRO A  33
HIS A 277
VAL A 279
 U  N3472 ( 4.3A)
None
A  N3475 ( 4.2A)
C  N3473 ( 4.5A)
 0.90A 3em0B-5an9A:
undetectable		 3em0B-5an9A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ce0 NATIVE CONSERPIN
WITH Z-VARIANT
(E342K)

(synthetic
construct) 		PF00079
(Serpin) 		4 PRO A 227
PRO A 361
ASN A 360
GLY A 356
 None
 0.94A 3em0B-5ce0A:
1.1		 3em0B-5ce0A:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fqe BETA-N-ACETYLGALACTO
SAMINIDASE

(Clostridium
perfringens) 		PF13320
(DUF4091) 		4 PRO A 131
ASN A 133
VAL A 162
GLY A 137
 None
 0.89A 3em0B-5fqeA:
undetectable		 3em0B-5fqeA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5frd CARBOXYLESTERASE
(EST-2)

(Archaeoglobus
fulgidus) 		PF12697
(Abhydrolase_6) 		4 PRO A  52
ASN A  53
HIS A  54
GLY A  91
 None
 0.63A 3em0B-5frdA:
undetectable		 3em0B-5frdA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gsl 778AA LONG
HYPOTHETICAL
BETA-GALACTOSIDASE

(Pyrococcus
horikoshii) 		PF02449
(Glyco_hydro_42) 		4 ILE A 111
PRO A 112
TYR A 261
GLY A  99
 None
 0.93A 3em0B-5gslA:
undetectable		 3em0B-5gslA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5idb NATTERIN-3

(Crassostrea
gigas) 		no annotation 4 ILE B  12
PRO B  13
PRO B 112
GLY B  50
 None
 0.79A 3em0B-5idbB:
undetectable		 3em0B-5idbB:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 ILE A 436
ASN A 488
VAL A 364
GLY A 365
 None
 0.83A 3em0B-5ip9A:
undetectable		 3em0B-5ip9A:
5.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j7u MAJOR CAPSID PROTEIN

(Faustovirus) 		PF04451
(Capsid_NCLDV) 		4 ILE A 314
PRO A 315
ASN A  78
GLY A 194
 None
 0.92A 3em0B-5j7uA:
4.1		 3em0B-5j7uA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o5c PUTATIVE
DECARBOXYLASE
INVOLVED IN
DESFERRIOXAMINE
BIOSYNTHESIS

(Erwinia
amylovora) 		no annotation 4 ILE A 405
PRO A 485
TYR A 299
GLY A 302
 None
 0.92A 3em0B-5o5cA:
undetectable		 3em0B-5o5cA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tz6 CURJ

(Moorea
producens) 		PF14765
(PS-DH) 		4 ILE A1163
PRO A1239
ASN A1238
GLY A1234
 7OD  A1301 ( 4.9A)
7OD  A1301 ( 4.7A)
None
None
 0.82A 3em0B-5tz6A:
2.4		 3em0B-5tz6A:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u8s DNA REPLICATION
LICENSING FACTOR
MCM4

(Saccharomyces
cerevisiae) 		PF00493
(MCM)
PF14551
(MCM_N)
PF17207
(MCM_OB) 		4 ILE 4 751
HIS 4 582
VAL 4 628
GLY 4 627
 None
 0.81A 3em0B-5u8s4:
undetectable		 3em0B-5u8s4:
9.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vj1 MDCA

(Pseudomonas
aeruginosa) 		PF16957
(Mal_decarbox_Al) 		4 ILE A 222
PRO A 295
HIS A 294
GLY A 313
 None
 0.86A 3em0B-5vj1A:
undetectable		 3em0B-5vj1A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wmm NRPS

(Micromonospora
sp. ML1) 		no annotation 4 TYR A 370
ASN A 372
HIS A 373
GLY A 172
 None
 0.84A 3em0B-5wmmA:
undetectable		 3em0B-5wmmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xww AMPHB

(Streptomyces
nodosus) 		no annotation 4 PRO A 365
PRO A  97
HIS A  90
GLY A 321
 None
 0.88A 3em0B-5xwwA:
undetectable		 3em0B-5xwwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xyi RIBOSOMAL PROTEIN
S13P/S18E, PUTATIVE

(Trichomonas
vaginalis) 		PF00416
(Ribosomal_S13) 		5 ILE S  35
PRO S  76
ASN S  75
HIS S  79
VAL S  46
 None
 0.94A 3em0B-5xyiS:
undetectable		 3em0B-5xyiS:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6k POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Acinetobacter
baumannii) 		no annotation 4 ILE A 100
PRO A  99
ASN A 221
GLY A 134
 None
 0.89A 3em0B-6d6kA:
2.1		 3em0B-6d6kA:
undetectable