SIMILAR PATTERNS OF AMINO ACIDS FOR 3ELZ_B_CHDB200
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1a5l | UREASE (ALPHASUBUNIT) (Klebsiellaaerogenes) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | PRO C 188VAL C 189THR C 171GLY C 157 | None | 1.16A | 3elzB-1a5lC:0.0 | 3elzB-1a5lC:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1amu | GRAMICIDINSYNTHETASE 1 (Brevibacillusbrevis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | PRO A 118THR A 513GLY A 516LYS A 517 | NoneNoneNoneAMP A 567 ( 2.8A) | 1.20A | 3elzB-1amuA:0.0 | 3elzB-1amuA:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1b0a | PROTEIN (FOLDBIFUNCTIONALPROTEIN) (Escherichiacoli) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 4 | PRO A 260VAL A 259THR A 148GLY A 145 | None | 1.11A | 3elzB-1b0aA:0.0 | 3elzB-1b0aA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d0n | HORSE PLASMAGELSOLIN (Equus caballus) |
PF00626(Gelsolin) | 4 | PRO A 726VAL A 495THR A 417GLY A 416 | None | 1.16A | 3elzB-1d0nA:0.0 | 3elzB-1d0nA:11.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e08 | [FE]-HYDROGENASE(LARGE SUBUNIT) (Desulfovibriodesulfuricans) |
PF02906(Fe_hyd_lg_C)PF13187(Fer4_9) | 4 | PRO A 223VAL A 226GLY A 205LYS A 201 | None | 1.06A | 3elzB-1e08A:undetectable | 3elzB-1e08A:17.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e19 | CARBAMATE KINASE (Pyrococcusfuriosus) |
PF00696(AA_kinase) | 4 | PRO A 168VAL A 119THR A 50GLY A 193 | None | 1.21A | 3elzB-1e19A:0.0 | 3elzB-1e19A:21.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fn9 | OUTER-CAPSID PROTEINSIGMA 3 (Reovirus sp.) |
PF00979(Reovirus_cap) | 4 | PRO A 332VAL A 334THR A 321GLY A 322 | None | 1.14A | 3elzB-1fn9A:0.0 | 3elzB-1fn9A:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h7w | DIHYDROPYRIMIDINEDEHYDROGENASE (Sus scrofa) |
PF01180(DHO_dh)PF07992(Pyr_redox_2)PF14691(Fer4_20)PF14697(Fer4_21) | 4 | PRO A 237VAL A 240THR A 132GLY A 153 | NoneNoneSF4 A1026 ( 4.8A)SF4 A1026 ( 3.9A) | 0.96A | 3elzB-1h7wA:0.0 | 3elzB-1h7wA:10.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hfe | PROTEIN (FE-ONLYHYDROGENASE(E.C.1.18.99.1)(LARGER SUBUNIT)) (Desulfovibriovulgaris) |
PF02906(Fe_hyd_lg_C)PF13237(Fer4_10) | 4 | PRO L 223VAL L 226GLY L 205LYS L 201 | None | 1.19A | 3elzB-1hfeL:undetectable | 3elzB-1hfeL:16.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iok | CHAPERONIN 60 (Paracoccusdenitrificans) |
PF00118(Cpn60_TCP1) | 4 | PRO A 497VAL A 500THR A 30GLY A 53 | None | 1.10A | 3elzB-1iokA:undetectable | 3elzB-1iokA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l6w | FRUCTOSE-6-PHOSPHATEALDOLASE 1 (Escherichiacoli) |
PF00923(TAL_FSA) | 4 | PRO A 187VAL A 190THR A 145GLY A 142 | None | 1.06A | 3elzB-1l6wA:undetectable | 3elzB-1l6wA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p31 | UDP-N-ACETYLMURAMATE--ALANINE LIGASE (Haemophilusinfluenzae) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | PRO A 431VAL A 429THR A 356GLY A 354 | None | 0.86A | 3elzB-1p31A:undetectable | 3elzB-1p31A:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1seq | MONOCLONAL ANTIBODYMNAC13 (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | PRO H 184VAL H 187THR H 153GLY H 157 | None | 1.11A | 3elzB-1seqH:undetectable | 3elzB-1seqH:23.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1txo | PUTATIVE BACTERIALENZYME (Mycobacteriumtuberculosis) |
PF13672(PP2C_2) | 4 | PRO A 196VAL A 197THR A 133GLY A 121 | None | 1.01A | 3elzB-1txoA:1.7 | 3elzB-1txoA:18.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1v4v | UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE (Thermusthermophilus) |
PF02350(Epimerase_2) | 4 | PRO A 23VAL A 24THR A 101GLY A 99 | None | 1.12A | 3elzB-1v4vA:undetectable | 3elzB-1v4vA:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ven | BETA-AMYLASE (Bacillus cereus) |
PF00686(CBM_20)PF01373(Glyco_hydro_14) | 4 | PRO A 419VAL A 417THR A 440GLY A 447 | None | 1.20A | 3elzB-1venA:undetectable | 3elzB-1venA:13.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vla | HYDROPEROXIDERESISTANCE PROTEINOSMC (Thermotogamaritima) |
PF02566(OsmC) | 4 | PRO A 102VAL A 63THR A 50GLY A 51 | None | 1.21A | 3elzB-1vlaA:undetectable | 3elzB-1vlaA:21.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wdi | HYPOTHETICAL PROTEINTT0907 (Thermusthermophilus) |
PF02547(Queuosine_synth) | 4 | PRO A 236VAL A 239THR A 258GLY A 257 | NoneNoneCIT A1322 (-3.0A)CIT A1322 (-3.2A) | 0.90A | 3elzB-1wdiA:undetectable | 3elzB-1wdiA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z3q | THAUMATIN-LIKEPROTEIN (Musa acuminata) |
PF00314(Thaumatin) | 4 | PRO A 178VAL A 100THR A 40GLY A 41 | EDO A 902 ( 4.7A)EDO A 903 (-4.3A)NoneNone | 1.10A | 3elzB-1z3qA:undetectable | 3elzB-1z3qA:18.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2a8b | RECEPTOR-TYPETYROSINE-PROTEINPHOSPHATASE R (Homo sapiens) |
PF00102(Y_phosphatase) | 4 | PRO A 428VAL A 405THR A 595GLY A 591 | None | 1.03A | 3elzB-2a8bA:undetectable | 3elzB-2a8bA:18.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c7z | 3-KETOACYL-COATHIOLASE 2 (Arabidopsisthaliana) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | PRO A 81VAL A 82THR A 133GLY A 103 | None | 1.14A | 3elzB-2c7zA:0.2 | 3elzB-2c7zA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2f00 | UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (Escherichiacoli) |
PF01225(Mur_ligase)PF02875(Mur_ligase_C)PF08245(Mur_ligase_M) | 4 | PRO A 234VAL A 235THR A 133GLY A 129 | None | 1.14A | 3elzB-2f00A:2.4 | 3elzB-2f00A:13.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m56 | CAMPHOR5-MONOOXYGENASE (Pseudomonasputida) |
PF00067(p450) | 4 | PRO A 122VAL A 123THR A 252GLY A 248 | NoneNoneHEM A 501 (-3.4A)HEM A 501 (-3.9A) | 0.99A | 3elzB-2m56A:undetectable | 3elzB-2m56A:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2p5x | N-ACETYLSEROTONINO-METHYLTRANSFERASE-LIKE PROTEIN (Homo sapiens) |
PF02545(Maf) | 4 | PRO A 39VAL A 37THR A 123GLY A 198 | None | 1.17A | 3elzB-2p5xA:1.1 | 3elzB-2p5xA:20.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vnu | EXOSOME COMPLEXEXONUCLEASE RRP44 (Saccharomycescerevisiae) |
PF00773(RNB)PF17215(Rrp44_S1)PF17216(Rrp44_CSD1) | 4 | VAL D 499THR D 592GLY D 591LYS D 887 | None | 1.08A | 3elzB-2vnuD:2.4 | 3elzB-2vnuD:11.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wkn | FORMAMIDASE (Delftiaacidovorans) |
PF03069(FmdA_AmdA) | 4 | PRO A 36VAL A 78GLY A 282LYS A 285 | None | 1.12A | 3elzB-2wknA:undetectable | 3elzB-2wknA:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yv1 | SUCCINYL-COA LIGASE[ADP-FORMING]SUBUNIT ALPHA (Methanocaldococcusjannaschii) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 4 | PRO A 144VAL A 147THR A 206GLY A 154 | None | 1.13A | 3elzB-2yv1A:undetectable | 3elzB-2yv1A:20.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3af5 | PUTATIVEUNCHARACTERIZEDPROTEIN PH1404 (Pyrococcushorikoshii) |
PF07521(RMMBL)PF10996(Beta-Casp)PF16661(Lactamase_B_6)PF17214(KH_7) | 4 | PRO A 611VAL A 607THR A 255GLY A 366 | None | 1.00A | 3elzB-3af5A:undetectable | 3elzB-3af5A:12.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cax | UNCHARACTERIZEDPROTEIN PF0695 (Pyrococcusfuriosus) |
PF01814(Hemerythrin)PF13596(PAS_10) | 4 | PRO A 299VAL A 297THR A 127GLY A 122 | None | 1.17A | 3elzB-3caxA:undetectable | 3elzB-3caxA:14.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dhv | D-ALANINE-POLY(PHOSPHORIBITOL) LIGASE (Bacillus cereus) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | PRO A 80THR A 488GLY A 491LYS A 492 | NoneNoneNoneDAL A 701 ( 3.2A) | 0.94A | 3elzB-3dhvA:undetectable | 3elzB-3dhvA:15.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dwi | CYSTEINE SYNTHASE B (Mycobacteriumtuberculosis) |
PF00291(PALP) | 4 | PRO A 15VAL A 17GLY A 297LYS A 299 | None | 1.13A | 3elzB-3dwiA:undetectable | 3elzB-3dwiA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eef | N-CARBAMOYLSARCOSINEAMIDASE RELATEDPROTEIN (Thermoplasmaacidophilum) |
PF00857(Isochorismatase) | 4 | PRO A 81VAL A 75THR A 127GLY A 95 | None | 1.14A | 3elzB-3eefA:undetectable | 3elzB-3eefA:19.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3elz | ILEAL BILEACID-BINDING PROTEIN (Danio rerio) |
PF14651(Lipocalin_7) | 5 | PRO A 24VAL A 27THR A 73GLY A 75LYS A 77 | CHD A 200 (-4.7A)CHD A 152 ( 4.3A)CHD A 200 (-3.1A)CHD A 200 (-3.4A)CHD A 153 ( 4.6A) | 1.08A | 3elzB-3elzA:24.8 | 3elzB-3elzA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f41 | PHYTASE (Mitsuokellamultacida) |
PF14566(PTPlike_phytase) | 4 | PRO A 323VAL A 319THR A 96GLY A 93 | None | 0.87A | 3elzB-3f41A:undetectable | 3elzB-3f41A:11.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fii | BOTULINUM NEUROTOXINTYPE F (Clostridiumbotulinum) |
PF01742(Peptidase_M27) | 4 | PRO A 25VAL A 137THR A 123GLY A 119 | None | 1.17A | 3elzB-3fiiA:undetectable | 3elzB-3fiiA:15.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g1u | ADENOSYLHOMOCYSTEINASE (Leishmaniamajor) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | PRO A 353VAL A 356THR A 274GLY A 224 | None | 0.94A | 3elzB-3g1uA:undetectable | 3elzB-3g1uA:15.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3h9u | ADENOSYLHOMOCYSTEINASE (Trypanosomabrucei) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | PRO A 353VAL A 356THR A 274GLY A 224 | None | 0.93A | 3elzB-3h9uA:undetectable | 3elzB-3h9uA:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hly | FLAVODOXIN-LIKEDOMAIN (Synechococcuselongatus) |
no annotation | 4 | PRO A 383VAL A 379THR A 396GLY A 395 | None | 0.92A | 3elzB-3hlyA:undetectable | 3elzB-3hlyA:19.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hut | PUTATIVEBRANCHED-CHAIN AMINOACID ABC TRANSPORTER (Rhodospirillumrubrum) |
PF13458(Peripla_BP_6) | 5 | PRO A 311VAL A 300THR A 358GLY A 356LYS A 369 | None | 1.46A | 3elzB-3hutA:undetectable | 3elzB-3hutA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ia4 | DIHYDROFOLATEREDUCTASE (Moritellaprofunda) |
PF00186(DHFR_1) | 4 | PRO A 71VAL A 74THR A 100GLY A 98 | NoneNoneNDP A 163 (-2.9A)NDP A 163 (-3.4A) | 1.01A | 3elzB-3ia4A:undetectable | 3elzB-3ia4A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3irv | CYSTEINE HYDROLASE (Pseudomonassavastanoi) |
PF00857(Isochorismatase) | 4 | PRO A 137VAL A 131THR A 183GLY A 151 | None | 1.16A | 3elzB-3irvA:undetectable | 3elzB-3irvA:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j83 | ESX-1SECRETION-ASSOCIATEDPROTEIN ESPB (Mycobacteriumtuberculosis) |
no annotation | 4 | PRO A 275VAL A 273THR A 158GLY A 155 | None | 1.20A | 3elzB-3j83A:undetectable | 3elzB-3j83A:15.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l07 | BIFUNCTIONAL PROTEINFOLD (Francisellatularensis) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 4 | PRO A 258VAL A 257THR A 147GLY A 144 | IMD A 503 (-4.4A)NoneEDO A 506 ( 3.5A)None | 1.16A | 3elzB-3l07A:undetectable | 3elzB-3l07A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m1u | PUTATIVEGAMMA-D-GLUTAMYL-L-DIAMINO ACIDENDOPEPTIDASE (Desulfovibriovulgaris) |
PF00877(NLPC_P60)PF12912(N_NLPC_P60)PF12913(SH3_6)PF12914(SH3_7) | 4 | PRO A 278VAL A 277THR A 342GLY A 260 | None | 1.20A | 3elzB-3m1uA:undetectable | 3elzB-3m1uA:15.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n58 | ADENOSYLHOMOCYSTEINASE (Brucellaabortus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | PRO A 388VAL A 391THR A 311GLY A 261 | K A 2 ( 4.8A)NoneNoneNone | 0.93A | 3elzB-3n58A:undetectable | 3elzB-3n58A:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o8o | 6-PHOSPHOFRUCTOKINASE SUBUNIT BETA (Saccharomycescerevisiae) |
PF00365(PFK) | 4 | PRO B 459VAL B 462THR B 405GLY B 402 | None | 1.06A | 3elzB-3o8oB:undetectable | 3elzB-3o8oB:10.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3one | ADENOSYLHOMOCYSTEINASE (Lupinus luteus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | PRO A 405VAL A 408THR A 324GLY A 274 | NA A 509 ( 4.8A)NoneNoneNone | 0.91A | 3elzB-3oneA:undetectable | 3elzB-3oneA:14.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p28 | GREEN FLUORESCENTPROTEIN (Aequoreavictoria) |
PF01353(GFP) | 4 | VAL A 102THR A 138GLY A 112LYS A 110 | None | 1.14A | 3elzB-3p28A:0.9 | 3elzB-3p28A:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r3q | SUPPRESSOR PROTEINSTP22 OFTEMPERATURE-SENSITIVE ALPHA-FACTORRECEPTOR ANDARGININE PERMEASE (Saccharomycescerevisiae) |
PF05743(UEV) | 4 | PRO A 10VAL A 9THR A 68GLY A 67 | None | 1.21A | 3elzB-3r3qA:1.4 | 3elzB-3r3qA:19.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r3s | OXIDOREDUCTASE (Salmonellaenterica) |
PF13561(adh_short_C2) | 4 | PRO A 267VAL A 268THR A 254GLY A 290 | None | 1.21A | 3elzB-3r3sA:undetectable | 3elzB-3r3sA:19.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r44 | FATTY ACYL COASYNTHETASE FADD13(FATTY-ACYL-COASYNTHETASE) (Mycobacteriumtuberculosis) |
PF00501(AMP-binding)PF13193(AMP-binding_C) | 4 | PRO A 411VAL A 409THR A 463GLY A 462 | None | 1.09A | 3elzB-3r44A:undetectable | 3elzB-3r44A:13.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sun | DNA POLYMERASE (Escherichiavirus RB69) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 4 | PRO A 738VAL A 741THR A 703GLY A 882 | None | 1.09A | 3elzB-3sunA:undetectable | 3elzB-3sunA:10.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t3o | METAL DEPENDENTHYDROLASE (Thermusthermophilus) |
PF07521(RMMBL)PF12706(Lactamase_B_2) | 4 | PRO A 391VAL A 198THR A 74GLY A 157 | None | 1.21A | 3elzB-3t3oA:undetectable | 3elzB-3t3oA:11.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t6p | BACULOVIRAL IAPREPEAT-CONTAININGPROTEIN 2 (Homo sapiens) |
PF00619(CARD)PF00653(BIR)PF13920(zf-C3HC4_3) | 4 | PRO A 280VAL A 283THR A 612GLY A 611 | None | 1.16A | 3elzB-3t6pA:undetectable | 3elzB-3t6pA:17.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wob | HYPOTHETICAL PROTEIN (Sus scrofa) |
PF01419(Jacalin) | 4 | PRO A 48VAL A 49GLY A 68LYS A 66 | None | 1.06A | 3elzB-3wobA:undetectable | 3elzB-3wobA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x1l | CMR4 (Archaeoglobusfulgidus) |
PF03787(RAMPs) | 4 | PRO C 134VAL C 135THR C 40GLY C 41 | None | 1.21A | 3elzB-3x1lC:undetectable | 3elzB-3x1lC:19.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zq4 | RIBONUCLEASE J 1 (Bacillussubtilis) |
PF00753(Lactamase_B)PF07521(RMMBL) | 4 | PRO A 383VAL A 189THR A 73GLY A 149 | None | 1.16A | 3elzB-3zq4A:undetectable | 3elzB-3zq4A:14.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ato | TOXN (Bacillusthuringiensis) |
PF13958(ToxN_toxin) | 4 | PRO A 7VAL A 40THR A 104GLY A 111 | None | 1.01A | 3elzB-4atoA:undetectable | 3elzB-4atoA:23.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4b4u | BIFUNCTIONAL PROTEINFOLD (Acinetobacterbaumannii) |
PF00763(THF_DHG_CYH)PF02882(THF_DHG_CYH_C) | 4 | PRO A 258VAL A 257THR A 147GLY A 144 | EDO A1286 (-4.0A)EDO A1286 ( 4.9A)NoneNone | 1.17A | 3elzB-4b4uA:undetectable | 3elzB-4b4uA:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c3h | DNA-DIRECTED RNAPOLYMERASE I SUBUNITRPA190DNA-DIRECTED RNAPOLYMERASE I SUBUNITRPA12 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF00623(RNA_pol_Rpb1_2)PF04983(RNA_pol_Rpb1_3)PF04997(RNA_pol_Rpb1_1)PF04998(RNA_pol_Rpb1_5)PF05000(RNA_pol_Rpb1_4)PF01096(TFIIS_C)PF02150(RNA_POL_M_15KD) | 4 | PRO I 38VAL I 28THR A1275GLY A1277 | None | 1.09A | 3elzB-4c3hI:undetectable | 3elzB-4c3hI:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ci8 | ECHINODERMMICROTUBULE-ASSOCIATED PROTEIN-LIKE 1 (Homo sapiens) |
PF00400(WD40)PF03451(HELP) | 4 | PRO A 418VAL A 421THR A 448GLY A 445 | None | 1.21A | 3elzB-4ci8A:undetectable | 3elzB-4ci8A:12.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4da1 | PROTEIN PHOSPHATASE1K, MITOCHONDRIAL (Homo sapiens) |
PF00481(PP2C) | 4 | PRO A 252VAL A 244THR A 189GLY A 207 | None | 1.07A | 3elzB-4da1A:1.6 | 3elzB-4da1A:17.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gpc | HEME OXYGENASE (Corynebacteriumdiphtheriae) |
PF01126(Heme_oxygenase) | 4 | PRO A 123VAL A 126GLY A 7LYS A 4 | None | 1.15A | 3elzB-4gpcA:undetectable | 3elzB-4gpcA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hnn | DIHYDRODIPICOLINATESYNTHASE (Vitis vinifera) |
PF00701(DHDPS) | 4 | PRO A 159VAL A 187THR A 173GLY A 169 | None | 1.06A | 3elzB-4hnnA:undetectable | 3elzB-4hnnA:18.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hrw | CYTIDINE ANDDEOXYCYTIDYLATEDEAMINASEZINC-BINDING REGION (Nitrosomonaseuropaea) |
PF00383(dCMP_cyt_deam_1) | 4 | PRO A 47VAL A 37THR A 163GLY A 164 | None | 0.93A | 3elzB-4hrwA:undetectable | 3elzB-4hrwA:20.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ixu | ARGINASE-2,MITOCHONDRIAL (Homo sapiens) |
PF00491(Arginase) | 4 | PRO A 151VAL A 175THR A 126GLY A 125 | None | 1.17A | 3elzB-4ixuA:undetectable | 3elzB-4ixuA:17.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jru | THAUMATIN-LIKEPROTEIN (Vitis vinifera) |
PF00314(Thaumatin) | 4 | PRO A 203VAL A 124THR A 64GLY A 65 | GOL A 303 (-4.6A)GOL A 303 (-4.3A)NoneNone | 1.13A | 3elzB-4jruA:undetectable | 3elzB-4jruA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ky0 | PROTON/GLUTAMATESYMPORTER, SDFFAMILY (Thermococcuskodakarensis) |
PF00375(SDF) | 4 | PRO A 155VAL A 156THR A 283GLY A 282 | None | 1.18A | 3elzB-4ky0A:undetectable | 3elzB-4ky0A:15.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m64 | MELIBIOSE CARRIERPROTEIN (Salmonellaenterica) |
PF13347(MFS_2) | 4 | PRO A 60VAL A 371THR A 222GLY A 225 | None | 1.05A | 3elzB-4m64A:undetectable | 3elzB-4m64A:13.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nle | ADENYLOSUCCINATELYASE (Mycolicibacteriumsmegmatis) |
PF00206(Lyase_1)PF10397(ADSL_C) | 4 | PRO A 184VAL A 225THR A 101GLY A 190 | None | 1.21A | 3elzB-4nleA:undetectable | 3elzB-4nleA:15.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nov | XYLOSIDASE/ARABINOFURANOSIDASE XSA43E (Butyrivibrioproteoclasticus) |
PF04616(Glyco_hydro_43) | 4 | PRO A 302VAL A 246THR A 274GLY A 253 | None | 0.81A | 3elzB-4novA:2.5 | 3elzB-4novA:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p98 | EXTRACELLULARSOLUTE-BINDINGPROTEIN (Conexibacterwoesei) |
PF02608(Bmp) | 4 | PRO A 166VAL A 171THR A 240GLY A 242 | None | 1.02A | 3elzB-4p98A:undetectable | 3elzB-4p98A:20.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q60 | PROLINE RACEMASE (Burkholderiamultivorans) |
PF05544(Pro_racemase) | 4 | PRO A 16VAL A 61THR A 241GLY A 240 | NoneNonePYC A 402 (-3.6A)PYC A 402 (-4.0A) | 1.21A | 3elzB-4q60A:undetectable | 3elzB-4q60A:17.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qqr | 3,5-EPIMERASE/4-REDUCTASE (Arabidopsisthaliana) |
PF04321(RmlD_sub_bind) | 4 | PRO A 194VAL A 226THR A 113GLY A 114 | None | 1.15A | 3elzB-4qqrA:undetectable | 3elzB-4qqrA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ra7 | PEPTIDOGLYCANGLYCOSYLTRANSFERASE (Atopobiumparvulum) |
PF00905(Transpeptidase) | 4 | PRO A 638VAL A 917THR A 765GLY A 762 | None | 0.77A | 3elzB-4ra7A:0.6 | 3elzB-4ra7A:13.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rk0 | LACI FAMILYSUGAR-BINDINGTRANSCRIPTIONALREGULATOR (Enterococcusfaecalis) |
PF13377(Peripla_BP_3) | 4 | PRO A 82VAL A 278THR A 222GLY A 229 | None | 1.09A | 3elzB-4rk0A:undetectable | 3elzB-4rk0A:20.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tqt | D-HYDANTOINASE (Brucella suis) |
PF01979(Amidohydro_1) | 4 | PRO A 362VAL A 355THR A 90GLY A 88 | None | 1.03A | 3elzB-4tqtA:undetectable | 3elzB-4tqtA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4twi | NAD-DEPENDENTPROTEIN DEACYLASE 1 (Archaeoglobusfulgidus) |
PF02146(SIR2) | 4 | PRO A 164VAL A 167THR A 186GLY A 20 | None | 1.15A | 3elzB-4twiA:undetectable | 3elzB-4twiA:21.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u9p | UPF0264 PROTEINMJ1099 (Methanocaldococcusjannaschii) |
PF04476(4HFCP_synth) | 4 | VAL A 128THR A 58GLY A 35LYS A 27 | None | 0.87A | 3elzB-4u9pA:undetectable | 3elzB-4u9pA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wnz | CRISPR SYSTEM CMRSUBUNIT CMR4 (Pyrococcusfuriosus) |
PF03787(RAMPs) | 4 | PRO A 93VAL A 94THR A 35GLY A 36 | None | 1.21A | 3elzB-4wnzA:undetectable | 3elzB-4wnzA:17.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x8d | SULFOXIDE SYNTHASEEGTB (Mycolicibacteriumthermoresistibile) |
PF03781(FGE-sulfatase)PF12867(DinB_2) | 4 | PRO A 336VAL A 358THR A 171GLY A 170 | None | 1.02A | 3elzB-4x8dA:undetectable | 3elzB-4x8dA:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4y23 | GAMMA GLUTAMYLTRANSPEPTIDASE,GAMMA-GLUTAMYLTRANSPEPTIDASE (Bacilluslicheniformis) |
PF01019(G_glu_transpept) | 4 | PRO A 429VAL A 248THR A 146GLY A 89 | None | 1.20A | 3elzB-4y23A:1.5 | 3elzB-4y23A:13.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z42 | UREASE SUBUNIT ALPHA (Yersiniaenterocolitica) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | PRO C 193VAL C 194THR C 176GLY C 162 | None | 1.16A | 3elzB-4z42C:undetectable | 3elzB-4z42C:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z42 | UREASE SUBUNIT ALPHA (Yersiniaenterocolitica) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | PRO C 193VAL C 194THR C 176GLY C 163 | None | 1.18A | 3elzB-4z42C:undetectable | 3elzB-4z42C:13.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z7r | COENZYME PQQSYNTHESIS PROTEIN B (Methylobacteriumextorquens) |
PF12706(Lactamase_B_2) | 4 | PRO A 271VAL A 272THR A 247GLY A 245 | None | 1.20A | 3elzB-4z7rA:undetectable | 3elzB-4z7rA:21.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cef | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Cryptococcusneoformans) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | PRO A 164VAL A 162THR A 349GLY A 346 | None | 1.17A | 3elzB-5cefA:undetectable | 3elzB-5cefA:17.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5da8 | 60 KDA CHAPERONIN (Chlorobaculumtepidum) |
PF00118(Cpn60_TCP1) | 4 | PRO A 497VAL A 500THR A 30GLY A 53 | None | 1.18A | 3elzB-5da8A:undetectable | 3elzB-5da8A:14.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5eo3 | PROTEIN PELOTAHOMOLOG (Homo sapiens) |
PF03465(eRF1_3) | 4 | PRO A 369VAL A 370THR A 342GLY A 341 | None | 1.21A | 3elzB-5eo3A:undetectable | 3elzB-5eo3A:21.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h64 | SERINE/THREONINE-PROTEIN KINASE MTOR (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08771(FRB_dom)PF11865(DUF3385) | 4 | PRO A2522VAL A2525THR A2390GLY A2391 | None | 1.05A | 3elzB-5h64A:undetectable | 3elzB-5h64A:4.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hh9 | PVDN (Pseudomonasaeruginosa) |
PF00266(Aminotran_5) | 4 | PRO A 65VAL A 68THR A 122GLY A 261 | NoneNonePLP A 501 (-3.4A)PLP A 501 ( 4.1A) | 1.13A | 3elzB-5hh9A:undetectable | 3elzB-5hh9A:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5jwz | CELLULOSE-BINDINGFAMILY II (Streptomycessp. SirexAA-E) |
PF02012(BNR) | 4 | PRO A 291VAL A 292THR A 265GLY A 271 | None | 1.11A | 3elzB-5jwzA:undetectable | 3elzB-5jwzA:11.63 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m2n | ELONGATOR COMPLEXPROTEIN 2 (Saccharomycescerevisiae) |
PF00400(WD40) | 4 | PRO A 43VAL A 30THR A 361GLY A 359 | None | 0.70A | 3elzB-5m2nA:undetectable | 3elzB-5m2nA:10.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vvw | UDP-N-ACETYLMURAMATE--L-ALANINE LIGASE (Pseudomonasaeruginosa) |
PF01225(Mur_ligase)PF08245(Mur_ligase_M) | 4 | PRO A 230VAL A 231THR A 129GLY A 125 | None | 1.21A | 3elzB-5vvwA:undetectable | 3elzB-5vvwA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w4b | ADENOSYLHOMOCYSTEINASE (Homo sapiens) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | PRO A 354VAL A 357THR A 275GLY A 225 | None | 0.95A | 3elzB-5w4bA:undetectable | 3elzB-5w4bA:16.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wdu | BNAB 35O22 FAB LIGHTCHAIN (Homo sapiens) |
no annotation | 4 | PRO I 26VAL I 27THR I 102GLY I 101 | None | 0.81A | 3elzB-5wduI:undetectable | 3elzB-5wduI:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xko | CYTIDINE/DEOXYCYTIDYLATE DEAMINASE,ZINC-BINDING REGION (Mycolicibacteriumsmegmatis) |
PF00383(dCMP_cyt_deam_1) | 4 | PRO A 123VAL A 124THR A 105GLY A 83 | NoneNoneNoneCAC A 201 (-4.1A) | 0.90A | 3elzB-5xkoA:undetectable | 3elzB-5xkoA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5z9s | GLYCOSYL HYDROLASEFAMILY 3 PROTEIN (Bifidobacteriumlongum) |
no annotation | 4 | PRO A 410VAL A 466THR A 423GLY A 420 | None | 1.20A | 3elzB-5z9sA:undetectable | 3elzB-5z9sA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6aph | ADENOSYLHOMOCYSTEINASE (Elizabethkingiaanophelis) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | PRO A 359VAL A 362THR A 280GLY A 230 | None | 0.90A | 3elzB-6aphA:undetectable | 3elzB-6aphA:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ck9 | 35O22 SCFV LIGHTCHAIN PORTION (Homo sapiens) |
no annotation | 4 | PRO E 26VAL E 27THR E 102GLY E 101 | None | 1.05A | 3elzB-6ck9E:undetectable | 3elzB-6ck9E:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f5d | ATP SYNTHASE SUBUNITBETA (Trypanosomabrucei) |
no annotation | 4 | PRO D 355VAL D 353THR D 140GLY D 142 | None | 1.20A | 3elzB-6f5dD:undetectable | 3elzB-6f5dD:undetectable |