SIMILAR PATTERNS OF AMINO ACIDS FOR 3ELZ_A_CHDA200

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b3i PROTEIN
(PLASTOCYANIN)

(Prochlorothrix
hollandica) 		PF00127
(Copper-bind) 		4 PRO A  53
THR A  95
VAL A  96
GLY A  76
 None
 1.04A 3elzA-1b3iA:
0.0		 3elzA-1b3iA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bh6 SUBTILISIN DY

(Bacillus
licheniformis) 		PF00082
(Peptidase_S8) 		4 THR A   3
VAL A  81
GLY A  80
LYS A   1
 None
None
CA  A 501 ( 4.3A)
None
 1.08A 3elzA-1bh6A:
0.0		 3elzA-1bh6A:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1bhu METALLOPROTEINASE
INHIBITOR

(Streptomyces
nigrescens) 		PF03995
(Inhibitor_I36) 		4 PRO A  90
THR A  74
VAL A  75
GLY A  76
 None
 1.02A 3elzA-1bhuA:
undetectable		 3elzA-1bhuA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1de6 L-RHAMNOSE ISOMERASE

(Escherichia
coli) 		PF06134
(RhaA) 		4 PRO A 141
THR A 246
VAL A 247
GLY A 248
 None
 0.68A 3elzA-1de6A:
0.0		 3elzA-1de6A:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvf TAGATOSE-BISPHOSPHAT
E ALDOLASE AGAY

(Escherichia
coli) 		PF01116
(F_bP_aldolase) 		4 PRO A 157
THR A 227
VAL A 226
GLY A 225
 None
 0.78A 3elzA-1gvfA:
0.0		 3elzA-1gvfA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ji6 PESTICIDIAL CRYSTAL
PROTEIN CRY3BB

(Bacillus
thuringiensis) 		PF00555
(Endotoxin_M)
PF03944
(Endotoxin_C)
PF03945
(Endotoxin_N) 		4 PRO A 320
THR A 407
VAL A 421
GLY A 420
 None
 1.05A 3elzA-1ji6A:
0.0		 3elzA-1ji6A:
11.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ksi COPPER AMINE OXIDASE

(Pisum sativum) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 THR A 515
VAL A 517
GLY A 518
LYS A 514
 None
 0.93A 3elzA-1ksiA:
0.0		 3elzA-1ksiA:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pw4 GLYCEROL-3-PHOSPHATE
TRANSPORTER

(Escherichia
coli) 		PF07690
(MFS_1) 		4 PRO A 277
THR A 407
VAL A 408
GLY A 405
 None
 1.10A 3elzA-1pw4A:
0.0		 3elzA-1pw4A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qr4 PROTEIN (TENASCIN)

(Gallus gallus) 		PF00041
(fn3) 		4 PRO A 110
THR A  86
VAL A  87
GLY A  61
 None
 0.98A 3elzA-1qr4A:
1.2		 3elzA-1qr4A:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tme THEILER'S MURINE
ENCEPHALOMYELITIS
VIRUS (SUBUNIT VP2)

(Cardiovirus B) 		PF00073
(Rhv) 		4 PRO 2 190
THR 2  29
VAL 2  30
GLY 2  31
 None
 1.14A 3elzA-1tme2:
undetectable		 3elzA-1tme2:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v8b ADENOSYLHOMOCYSTEINA
SE

(Plasmodium
falciparum) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 PRO A  15
THR A  98
VAL A  99
LYS A   5
 None
 1.17A 3elzA-1v8bA:
undetectable		 3elzA-1v8bA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wiu TWITCHIN 18TH IGSF
MODULE

(Caenorhabditis
elegans) 		PF07679
(I-set) 		4 THR A  37
VAL A  38
GLY A  39
LYS A  74
 None
 1.11A 3elzA-1wiuA:
undetectable		 3elzA-1wiuA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xrs D-LYSINE
5,6-AMINOMUTASE
ALPHA SUBUNIT

(Acetoanaerobium
sticklandii) 		PF09043
(Lys-AminoMut_A) 		4 PRO A 488
THR A  35
VAL A 498
GLY A 497
 None
 1.05A 3elzA-1xrsA:
undetectable		 3elzA-1xrsA:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yts YERSINIA PROTEIN
TYROSINE PHOSPHATASE

(Yersinia
enterocolitica) 		PF00102
(Y_phosphatase) 		4 PRO A 464
THR A 254
VAL A 251
GLY A 252
 None
 0.96A 3elzA-1ytsA:
undetectable		 3elzA-1ytsA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z6o FERRITIN LIGHT CHAIN
FERRITIN HEAVY CHAIN

(Trichoplusia
ni;
Trichoplusia ni) 		PF00210
(Ferritin)
PF00210
(Ferritin) 		4 PRO M  96
THR A  95
VAL A  94
LYS M  48
 None
 0.97A 3elzA-1z6oM:
undetectable		 3elzA-1z6oM:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zvu TOPOISOMERASE IV
SUBUNIT A

(Escherichia
coli) 		PF00521
(DNA_topoisoIV)
PF03989
(DNA_gyraseA_C) 		4 PRO A 112
THR A  66
VAL A  67
GLY A  68
 None
 0.94A 3elzA-1zvuA:
undetectable		 3elzA-1zvuA:
11.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2aqt SUPEROXIDE DISMUTASE
[CU-ZN]

(Neisseria
meningitidis) 		no annotation 4 PRO C 178
THR C 130
VAL C 131
GLY C  74
 None
 1.12A 3elzA-2aqtC:
2.1		 3elzA-2aqtC:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2azp HYPOTHETICAL PROTEIN
PA1268

(Pseudomonas
aeruginosa) 		PF05544
(Pro_racemase) 		4 PRO A 283
THR A 114
VAL A 116
GLY A 117
 None
 0.92A 3elzA-2azpA:
undetectable		 3elzA-2azpA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2e1m L-GLUTAMATE OXIDASE
L-GLUTAMATE OXIDASE
L-GLUTAMATE OXIDASE

(Streptomyces
sp. X-119-6;
Streptomyces
sp. X-119-6;
Streptomyces
sp. X-119-6) 		PF01593
(Amino_oxidase)
PF01593
(Amino_oxidase)
PF01593
(Amino_oxidase) 		4 PRO C 612
THR B 404
VAL A  64
GLY A  65
 None
None
None
FAD  A 801 (-3.4A)
 1.18A 3elzA-2e1mC:
undetectable		 3elzA-2e1mC:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2exr CYTOKININ
DEHYDROGENASE 7

(Arabidopsis
thaliana) 		PF01565
(FAD_binding_4)
PF09265
(Cytokin-bind) 		4 PRO A  71
THR A 167
VAL A 168
GLY A 169
 None
FAD  A 525 (-3.1A)
None
FAD  A 525 (-3.5A)
 1.06A 3elzA-2exrA:
undetectable		 3elzA-2exrA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fge ZINC METALLOPROTEASE
(INSULINASE FAMILY)

(Arabidopsis
thaliana) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		4 PRO A 784
THR A 606
VAL A 669
LYS A 607
 None
 1.11A 3elzA-2fgeA:
undetectable		 3elzA-2fgeA:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gen PROBABLE
TRANSCRIPTIONAL
REGULATOR

(Pseudomonas
aeruginosa) 		PF00440
(TetR_N) 		4 PRO A  97
THR A  26
VAL A  23
GLY A  22
 None
 1.08A 3elzA-2genA:
undetectable		 3elzA-2genA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ilu ALDEHYDE
DEHYDROGENASE A

(Escherichia
coli) 		PF00171
(Aldedh) 		4 PRO A 198
THR A 146
VAL A 145
GLY A 144
 None
 1.13A 3elzA-2iluA:
undetectable		 3elzA-2iluA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2m19 MOLYBDOPTERIN
CONVERTING FACTOR
SUBUNIT 1

(Haloferax
volcanii) 		PF02597
(ThiS) 		4 PRO A  56
THR A  29
VAL A  30
GLY A  31
 None
 1.15A 3elzA-2m19A:
undetectable		 3elzA-2m19A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mii PENICILLIN-BINDING
PROTEIN ACTIVATOR
LPOB

(Escherichia
coli) 		PF13036
(LpoB) 		4 PRO A  57
THR A  96
VAL A 169
GLY A  98
 None
 1.17A 3elzA-2miiA:
undetectable		 3elzA-2miiA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ozk URIDYLATE-SPECIFIC
ENDORIBONUCLEASE

(Severe acute
respiratory
syndrome-related
coronavirus) 		PF06471
(NSP11) 		4 PRO A 157
THR A 120
VAL A  77
GLY A  76
 None
 0.96A 3elzA-2ozkA:
undetectable		 3elzA-2ozkA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p9n ACTIN-RELATED
PROTEIN 2/3 COMPLEX
SUBUNIT 1B

(Bos taurus) 		PF00400
(WD40) 		4 PRO C  10
THR C  69
VAL C  58
GLY C  57
 None
 1.13A 3elzA-2p9nC:
undetectable		 3elzA-2p9nC:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfe ALKALINE SERINE
PROTEASE

(Thermobifida
fusca) 		PF00089
(Trypsin) 		4 PRO A  67
THR A 213
VAL A 212
GLY A 197
 None
AES  A1002 (-3.7A)
None
None
 1.15A 3elzA-2pfeA:
undetectable		 3elzA-2pfeA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qk4 TRIFUNCTIONAL PURINE
BIOSYNTHETIC PROTEIN
ADENOSINE-3

(Homo sapiens) 		PF01071
(GARS_A)
PF02843
(GARS_C)
PF02844
(GARS_N) 		4 PRO A 345
THR A 336
VAL A 337
GLY A 234
 None
 1.11A 3elzA-2qk4A:
undetectable		 3elzA-2qk4A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r1z BRCA1-ASSOCIATED
RING DOMAIN PROTEIN
1

(Homo sapiens) 		PF00533
(BRCT)
PF16589
(BRCT_2) 		4 PRO A 707
THR A 696
VAL A 695
GLY A 700
 None
 1.17A 3elzA-2r1zA:
undetectable		 3elzA-2r1zA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x12 FIMBRIAE-ASSOCIATED
PROTEIN FAP1

(Streptococcus
parasanguinis) 		no annotation 4 PRO A 388
THR A 355
VAL A 354
GLY A 353
 None
 1.16A 3elzA-2x12A:
1.2		 3elzA-2x12A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x58 PEROXISOMAL
BIFUNCTIONAL ENZYME

(Rattus
norvegicus) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		4 PRO A 295
VAL A 318
GLY A 319
LYS A 361
 None
 1.14A 3elzA-2x58A:
undetectable		 3elzA-2x58A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8v CLASS III CHITINASE,
PUTATIVE

(Aspergillus
fumigatus) 		PF00704
(Glyco_hydro_18) 		4 PRO A 269
THR A  41
VAL A  40
GLY A  39
 None
 1.17A 3elzA-2y8vA:
undetectable		 3elzA-2y8vA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yij PHOSPHOLIPASE
A1-IIGAMMA

(Arabidopsis
thaliana) 		PF01764
(Lipase_3) 		4 PRO A 305
THR A 351
VAL A 348
GLY A 347
 None
 1.15A 3elzA-2yijA:
undetectable		 3elzA-2yijA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yjn GLYCOSYLTRANSFERASE

(Saccharopolyspora
erythraea) 		PF06722
(DUF1205) 		4 PRO A  39
THR A 243
VAL A 244
GLY A 245
 None
 0.92A 3elzA-2yjnA:
undetectable		 3elzA-2yjnA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a74 LYSYL-TRNA
SYNTHETASE

(Geobacillus
stearothermophilus) 		PF00152
(tRNA-synt_2)
PF01336
(tRNA_anti-codon) 		4 THR A 121
VAL A 123
GLY A 124
LYS A 120
 None
 1.08A 3elzA-3a74A:
undetectable		 3elzA-3a74A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bmw CYCLOMALTODEXTRIN
GLUCANOTRANSFERASE

(Thermoanaerobacterium
thermosulfurigenes) 		PF00128
(Alpha-amylase)
PF00686
(CBM_20)
PF01833
(TIG) 		4 PRO A 555
THR A 668
VAL A 669
GLY A 642
 None
 0.97A 3elzA-3bmwA:
2.9		 3elzA-3bmwA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d8n UROPORPHYRINOGEN-III
SYNTHASE

(Thermus
thermophilus) 		PF02602
(HEM4) 		4 PRO A  37
THR A  59
VAL A  61
GLY A  62
 None
UP3  A 944 (-4.2A)
UP3  A 944 ( 3.8A)
None
 1.01A 3elzA-3d8nA:
undetectable		 3elzA-3d8nA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e6e ALANINE RACEMASE

(Enterococcus
faecalis) 		PF00842
(Ala_racemase_C)
PF01168
(Ala_racemase_N) 		4 PRO A  82
THR A  19
VAL A  22
GLY A  58
 None
 1.14A 3elzA-3e6eA:
undetectable		 3elzA-3e6eA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eh1 PROTEIN TRANSPORT
PROTEIN SEC24B

(Homo sapiens) 		PF00626
(Gelsolin)
PF04810
(zf-Sec23_Sec24)
PF04811
(Sec23_trunk)
PF04815
(Sec23_helical)
PF08033
(Sec23_BS) 		4 PRO A1075
THR A1056
VAL A1057
GLY A1054
 None
 1.11A 3elzA-3eh1A:
undetectable		 3elzA-3eh1A:
10.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3elz ILEAL BILE
ACID-BINDING PROTEIN

(Danio rerio) 		PF14651
(Lipocalin_7) 		5 PRO A  24
THR A  73
VAL A  74
GLY A  75
LYS A  77
 CHD  A 200 (-4.7A)
CHD  A 200 (-3.1A)
CHD  A 200 (-3.7A)
CHD  A 200 (-3.4A)
CHD  A 153 ( 4.6A)
 0.01A 3elzA-3elzA:
27.5		 3elzA-3elzA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3evt PHOSPHOGLYCERATE
DEHYDROGENASE

(Lactobacillus
plantarum) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C) 		4 PRO A 200
THR A 179
VAL A 180
GLY A 170
 None
 1.14A 3elzA-3evtA:
undetectable		 3elzA-3evtA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igz COFACTOR-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Leishmania
mexicana) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		4 PRO B 266
THR B 206
VAL B 205
GLY B 220
 None
 1.07A 3elzA-3igzB:
undetectable		 3elzA-3igzB:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kw7 LACCASE B

(Trametes sp.
AH28-2) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 THR A   6
VAL A   5
GLY A   3
LYS A   1
 None
 1.06A 3elzA-3kw7A:
undetectable		 3elzA-3kw7A:
13.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nm1 THIAMINE
BIOSYNTHETIC
BIFUNCTIONAL ENZYME

([Candida]
glabrata) 		PF02110
(HK)
PF02581
(TMP-TENI) 		4 PRO A 184
THR A  40
VAL A  39
GLY A  38
 None
 0.74A 3elzA-3nm1A:
undetectable		 3elzA-3nm1A:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nvl 2,3-BISPHOSPHOGLYCER
ATE-INDEPENDENT
PHOSPHOGLYCERATE
MUTASE

(Trypanosoma
brucei) 		PF01676
(Metalloenzyme)
PF06415
(iPGM_N) 		4 PRO A 265
THR A 205
VAL A 204
GLY A 219
 None
 0.98A 3elzA-3nvlA:
undetectable		 3elzA-3nvlA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oue CYTOCHROME C FAMILY
PROTEIN

(Geobacter
sulfurreducens) 		PF14522
(Cytochrome_C7) 		4 THR A 250
VAL A 252
GLY A 253
LYS A 249
 HEM  A 612 (-4.1A)
HEM  A 612 (-4.4A)
None
None
 0.96A 3elzA-3oueA:
undetectable		 3elzA-3oueA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pxx CARVEOL
DEHYDROGENASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 PRO A 107
THR A 131
VAL A 128
GLY A 127
 None
 1.11A 3elzA-3pxxA:
undetectable		 3elzA-3pxxA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qbo PHOSPHOSERINE
AMINOTRANSFERASE

(Yersinia pestis) 		PF00266
(Aminotran_5) 		4 PRO A 116
THR A 122
VAL A 121
GLY A  99
 None
 1.14A 3elzA-3qboA:
undetectable		 3elzA-3qboA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qnk PUTATIVE LIPOPROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 PRO A 245
THR A 364
VAL A 365
GLY A 351
 None
 1.15A 3elzA-3qnkA:
undetectable		 3elzA-3qnkA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s29 SUCROSE SYNTHASE 1

(Arabidopsis
thaliana) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		4 PRO A 714
THR A 680
VAL A 681
GLY A 678
 None
UDP  A 901 (-3.2A)
None
UDP  A 901 ( 3.7A)
 1.03A 3elzA-3s29A:
undetectable		 3elzA-3s29A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3sx2 PUTATIVE
3-KETOACYL-(ACYL-CAR
RIER-PROTEIN)
REDUCTASE

(Mycobacterium
avium) 		PF13561
(adh_short_C2) 		4 PRO A 112
THR A 134
VAL A 131
GLY A 130
 None
 1.08A 3elzA-3sx2A:
undetectable		 3elzA-3sx2A:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t8l ADENINE DEAMINASE 2

(Agrobacterium
fabrum) 		PF01979
(Amidohydro_1)
PF13382
(Adenine_deam_C) 		4 PRO A 316
THR A 115
VAL A 114
GLY A 113
 None
 1.08A 3elzA-3t8lA:
undetectable		 3elzA-3t8lA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3taw HYPOTHETICAL
GLYCOSIDE HYDROLASE

(Parabacteroides
distasonis) 		PF04041
(Glyco_hydro_130) 		4 PRO A 280
THR A 351
VAL A 352
GLY A 369
 EDO  A 394 (-3.9A)
UNL  A 388 ( 4.6A)
None
None
 1.18A 3elzA-3tawA:
undetectable		 3elzA-3tawA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tr5 PEPTIDE CHAIN
RELEASE FACTOR 3

(Coxiella
burnetii) 		PF00009
(GTP_EFTU)
PF16658
(RF3_C) 		4 PRO A 118
THR A  93
VAL A 437
GLY A 438
 None
 1.13A 3elzA-3tr5A:
undetectable		 3elzA-3tr5A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uxy SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Rhodobacter
sphaeroides) 		PF13561
(adh_short_C2) 		4 PRO A 212
THR A 203
VAL A 204
GLY A 201
 None
 1.15A 3elzA-3uxyA:
undetectable		 3elzA-3uxyA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3va6 TWO-COMPONENT SYSTEM
SENSOR HISTIDINE
KINASE

(Bacteroides
thetaiotaomicron) 		PF07494
(Reg_prop)
PF07495
(Y_Y_Y) 		4 PRO A 245
THR A 190
VAL A 220
GLY A 189
 None
 1.12A 3elzA-3va6A:
undetectable		 3elzA-3va6A:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vbe BETA-CYANOALNINE
SYNTHASE

(Glycine max) 		PF00291
(PALP) 		4 PRO A 267
THR A 177
VAL A 178
GLY A 175
 None
 1.01A 3elzA-3vbeA:
undetectable		 3elzA-3vbeA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wuy NITRILASE

(Synechocystis
sp. PCC 6803) 		PF00795
(CN_hydrolase) 		4 PRO A 257
THR A 159
VAL A 161
GLY A 162
 None
 1.11A 3elzA-3wuyA:
undetectable		 3elzA-3wuyA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zbf PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ROS

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		4 PRO A2021
THR A1963
VAL A1977
GLY A1962
 None
 1.12A 3elzA-3zbfA:
undetectable		 3elzA-3zbfA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zg8 PENICILLIN-BINDING
PROTEIN 4

(Listeria
monocytogenes) 		PF00905
(Transpeptidase)
PF00912
(Transgly) 		4 PRO B 441
THR B 561
VAL B 556
GLY B 560
 None
AIX  B 800 ( 3.8A)
None
None
 1.14A 3elzA-3zg8B:
0.5		 3elzA-3zg8B:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2l TWO-COMPONENT SYSTEM
SENSOR HISTIDINE
KINASE/RESPONSE

(Bacteroides
thetaiotaomicron) 		PF07494
(Reg_prop)
PF07495
(Y_Y_Y) 		4 PRO A 478
THR A 424
VAL A 454
GLY A 423
 None
 1.07A 3elzA-4a2lA:
undetectable		 3elzA-4a2lA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a2l TWO-COMPONENT SYSTEM
SENSOR HISTIDINE
KINASE/RESPONSE

(Bacteroides
thetaiotaomicron) 		PF07494
(Reg_prop)
PF07495
(Y_Y_Y) 		4 PRO A 612
THR A 560
VAL A 588
GLY A 559
 None
 1.02A 3elzA-4a2lA:
undetectable		 3elzA-4a2lA:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c3z MULTIDRUG
RESISTANCE-ASSOCIATE
D PROTEIN 1

(Homo sapiens) 		PF00005
(ABC_tran) 		4 PRO A 735
VAL A 810
GLY A 815
LYS A 818
 None
 1.13A 3elzA-4c3zA:
undetectable		 3elzA-4c3zA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ce5 AT-OMEGATA

(Aspergillus
terreus) 		PF01063
(Aminotran_4) 		4 PRO A  92
THR A 130
VAL A 127
GLY A 126
 None
 1.00A 3elzA-4ce5A:
undetectable		 3elzA-4ce5A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4eyg TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL

(Rhodopseudomonas
palustris) 		PF13458
(Peripla_BP_6) 		4 PRO A 253
THR A 390
GLY A 388
LYS A 389
 None
 1.12A 3elzA-4eygA:
undetectable		 3elzA-4eygA:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ipb UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF11396
(PepSY_like) 		4 PRO A 156
THR A  31
VAL A  28
GLY A  70
 None
 1.05A 3elzA-4ipbA:
2.3		 3elzA-4ipbA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jbd PROLINE RACEMASE

(Pseudomonas
putida) 		PF05544
(Pro_racemase) 		4 PRO A 135
THR A 114
VAL A 116
GLY A 117
 None
 0.77A 3elzA-4jbdA:
undetectable		 3elzA-4jbdA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jqt PUTATIVE GLYCOSYL
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF06439
(DUF1080) 		4 PRO A  59
THR A 198
VAL A 199
GLY A  52
 None
 1.14A 3elzA-4jqtA:
undetectable		 3elzA-4jqtA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lj2 CHORISMATE SYNTHASE

(Acinetobacter
baumannii) 		PF01264
(Chorismate_synt) 		4 PRO A 363
THR A  76
GLY A  33
LYS A  75
 None
 1.13A 3elzA-4lj2A:
undetectable		 3elzA-4lj2A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4m4w PRIMOSOMAL PROTEIN
DNAI

(Bacillus
subtilis) 		PF01695
(IstB_IS21)
PF07319
(DnaI_N) 		4 PRO J 198
THR J 247
VAL J 248
GLY J 246
 None
 1.08A 3elzA-4m4wJ:
undetectable		 3elzA-4m4wJ:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oon PENICILLIN-BINDING
PROTEIN 1A

(Pseudomonas
aeruginosa) 		PF00905
(Transpeptidase)
PF00912
(Transgly)
PF17092
(PCB_OB) 		4 PRO A 725
THR A 736
VAL A 737
GLY A 734
 None
None
None
2U4  A 901 ( 4.4A)
 1.15A 3elzA-4oonA:
undetectable		 3elzA-4oonA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4phz PARTICULATE METHANE
MONOOXYGENASE
SUBUNIT C

(Methylocystis
sp. ATCC 49242) 		no annotation 4 PRO K  97
THR K 255
VAL K 251
GLY K 250
 None
 1.01A 3elzA-4phzK:
undetectable		 3elzA-4phzK:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r9x COPPER HOMEOSTASIS
PROTEIN CUTC

(Bacillus
anthracis) 		PF03932
(CutC) 		4 PRO A 158
THR A 180
VAL A 179
GLY A 178
 None
 1.16A 3elzA-4r9xA:
undetectable		 3elzA-4r9xA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4s17 GLUTAMINE SYNTHETASE

(Bifidobacterium
adolescentis) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 PRO A 265
THR A  27
VAL A  32
GLY A  31
 None
 1.18A 3elzA-4s17A:
undetectable		 3elzA-4s17A:
13.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u1r ATP-DEPENDENT
6-PHOSPHOFRUCTOKINAS
E, PLATELET TYPE

(Homo sapiens) 		PF00365
(PFK) 		4 PRO A 544
THR A 479
VAL A 418
GLY A 419
 None
 1.17A 3elzA-4u1rA:
undetectable		 3elzA-4u1rA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4w8i PROBABLE
SPHINGOSINE-1-PHOSPH
ATE LYASE

(Legionella
pneumophila) 		PF00282
(Pyridoxal_deC) 		4 PRO A 280
THR A 352
VAL A 351
GLY A 350
 None
 0.83A 3elzA-4w8iA:
undetectable		 3elzA-4w8iA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y96 TRIOSEPHOSPHATE
ISOMERASE

(Gemmata
obscuriglobus) 		PF00121
(TIM) 		4 PRO A 220
THR A  36
VAL A  35
GLY A  34
 None
 0.61A 3elzA-4y96A:
undetectable		 3elzA-4y96A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a7v PUTATIVE GLYCOSIDASE
PH117-RELATED

(Bacteroides
thetaiotaomicron) 		PF04041
(Glyco_hydro_130) 		4 PRO B 272
THR B 342
VAL B 343
GLY B 360
 None
 1.11A 3elzA-5a7vB:
0.5		 3elzA-5a7vB:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a8f HUMAN SAFFOLD
VIRUS-3 VP2

(Cardiovirus B) 		PF00073
(Rhv) 		4 PRO C 194
THR C  29
VAL C  30
GLY C  31
 None
 1.12A 3elzA-5a8fC:
undetectable		 3elzA-5a8fC:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5drz HIV ANTIBODY F240
HEAVY CHAIN

(Homo sapiens) 		no annotation 4 PRO H 119
THR H 110
VAL H  11
GLY H  10
 None
 1.12A 3elzA-5drzH:
undetectable		 3elzA-5drzH:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ds0 PEPTIDASE M42

(Thaumarchaeota
archaeon SCGC
AB-539-E09) 		PF05343
(Peptidase_M42) 		4 THR A 105
VAL A 153
GLY A 152
LYS A 107
 None
 1.17A 3elzA-5ds0A:
undetectable		 3elzA-5ds0A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ea0 HEAVY CHAIN OF
ANTIBODY 7968 FAB
FRAGMENT

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 PRO H 121
THR H 112
VAL H  11
GLY H  10
 None
 1.17A 3elzA-5ea0H:
undetectable		 3elzA-5ea0H:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1k GEM-ASSOCIATED
PROTEIN 5

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		4 PRO A 512
THR A 446
VAL A 473
GLY A 445
 None
 1.18A 3elzA-5h1kA:
undetectable		 3elzA-5h1kA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hl6 PUTATIVE GAF SENSOR
PROTEIN

(Burkholderia
vietnamiensis) 		PF13185
(GAF_2) 		4 THR A  87
VAL A  84
GLY A  83
LYS A  82
 None
 1.03A 3elzA-5hl6A:
undetectable		 3elzA-5hl6A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ju6 BETA-GLUCOSIDASE

(Rasamsonia
emersonii) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		4 PRO A 349
THR A  66
VAL A  77
GLY A  78
 None
None
None
NAG  A 901 (-3.4A)
 1.06A 3elzA-5ju6A:
undetectable		 3elzA-5ju6A:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k0w CLASS B
CARBAPENEMASE GOB-18

(Elizabethkingia
meningoseptica) 		PF00753
(Lactamase_B) 		4 PRO A 150
THR A 144
VAL A 143
GLY A 132
 None
 1.07A 3elzA-5k0wA:
0.7		 3elzA-5k0wA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k50 L-THREONINE
3-DEHYDROGENASE

(Trypanosoma
brucei) 		no annotation 4 PRO A1078
THR A1142
VAL A1143
GLY A1145
 NAD  A1401 (-4.3A)
None
None
None
 1.03A 3elzA-5k50A:
undetectable		 3elzA-5k50A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ldr BETA-D-GALACTOSIDASE

(Paracoccus sp.
32d) 		PF00703
(Glyco_hydro_2)
PF02836
(Glyco_hydro_2_C)
PF02837
(Glyco_hydro_2_N) 		4 PRO B 304
THR B 406
VAL B 392
GLY B 391
 None
 0.80A 3elzA-5ldrB:
undetectable		 3elzA-5ldrB:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m11 IMMUNOREACTIVE 84KD
ANTIGEN PG93

(Porphyromonas
gingivalis) 		no annotation 4 PRO A 469
THR A 408
VAL A 442
GLY A 407
 None
 1.05A 3elzA-5m11A:
undetectable		 3elzA-5m11A:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m2o GROUP I DOCKERIN

(Ruminococcus
flavefaciens) 		no annotation 4 PRO B  94
THR B  75
VAL B  74
GLY B  73
 None
CA  B 202 ( 4.8A)
None
CA  B 202 (-4.5A)
 1.07A 3elzA-5m2oB:
undetectable		 3elzA-5m2oB:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nnb ISATIN HYDROLASE A

(Labrenzia
aggregata) 		no annotation 4 PRO A  35
THR A 189
VAL A 190
GLY A 191
 None
None
None
92K  A 302 ( 4.3A)
 1.08A 3elzA-5nnbA:
undetectable		 3elzA-5nnbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tp4 AMIDASE,
HYDANTOINASE/CARBAMO
YLASE FAMILY

(Burkholderia
ambifaria) 		PF01546
(Peptidase_M20) 		4 THR A 117
VAL A 410
GLY A 409
LYS A 119
 None
 0.89A 3elzA-5tp4A:
undetectable		 3elzA-5tp4A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ue8 PROTEIN UNC-13
HOMOLOG A

(Rattus
norvegicus) 		PF00130
(C1_1)
PF00168
(C2)
PF06292
(DUF1041)
PF10540
(Membr_traf_MHD) 		4 THR A 721
VAL A 718
GLY A 719
LYS A 720
 None
 1.15A 3elzA-5ue8A:
undetectable		 3elzA-5ue8A:
9.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ver KYNURENINE--OXOGLUTA
RATE TRANSAMINASE 3

(Mus musculus) 		no annotation 4 PRO A 344
THR A 286
VAL A 285
GLY A 280
 None
 1.15A 3elzA-5verA:
undetectable		 3elzA-5verA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xta VIRK PROTEIN

(Legionella
pneumophila) 		PF06903
(VirK) 		4 PRO A  34
THR A  93
VAL A  94
GLY A 104
 None
 1.10A 3elzA-5xtaA:
3.5		 3elzA-5xtaA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ca6 PCT64_35S HEAVY
CHAIN

(Homo sapiens) 		no annotation 4 PRO H 167
THR H 108
VAL H  89
GLY H  88
 None
 1.09A 3elzA-6ca6H:
undetectable		 3elzA-6ca6H:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cgs CADHERIN-7

(Mus musculus) 		no annotation 4 PRO A 120
THR A 204
VAL A 203
GLY A 114
 None
 1.16A 3elzA-6cgsA:
undetectable		 3elzA-6cgsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ems TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE

(Thermococcus
kodakarensis) 		no annotation 4 THR A  55
VAL A  57
GLY A  68
LYS A  54
 None
 1.14A 3elzA-6emsA:
undetectable		 3elzA-6emsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ez8 HUNTINGTIN

(Homo sapiens) 		no annotation 4 PRO A2238
THR A2175
VAL A2176
GLY A2174
 None
 0.99A 3elzA-6ez8A:
undetectable		 3elzA-6ez8A:
undetectable