SIMILAR PATTERNS OF AMINO ACIDS FOR 3EIG_A_MTXA200_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b8h DNA POLYMERASE
PROCESSIVITY
COMPONENT

(Escherichia
virus RB69) 		PF02916
(DNA_PPF)
PF09116
(gp45-slide_C) 		4 ASP A  46
ILE A  73
VAL A  52
THR A  31
 None
 1.13A 3eigA-1b8hA:
undetectable		 3eigA-1b8hA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dl5 PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE

(Thermotoga
maritima) 		PF01135
(PCMT) 		4 ARG A 273
ILE A 232
VAL A 267
THR A 257
 None
 1.19A 3eigA-1dl5A:
1.6		 3eigA-1dl5A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eu1 DIMETHYL SULFOXIDE
REDUCTASE

(Rhodobacter
sphaeroides) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		4 ARG A 315
ILE A 344
VAL A 182
THR A 215
 None
 1.19A 3eigA-1eu1A:
0.6		 3eigA-1eu1A:
13.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eyw PHOSPHOTRIESTERASE

(Brevundimonas
diminuta) 		PF02126
(PTE) 		4 ASP A 253
ILE A 228
VAL A 198
THR A 103
 None
None
None
KCX  A 169 ( 4.3A)
 0.83A 3eigA-1eywA:
undetectable		 3eigA-1eywA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1j1w ISOCITRATE
DEHYDROGENASE

(Azotobacter
vinelandii) 		PF03971
(IDH) 		4 ARG A  40
ILE A  42
VAL A 137
THR A  75
 None
 0.93A 3eigA-1j1wA:
undetectable		 3eigA-1j1wA:
13.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kuu CONSERVED PROTEIN

(Methanothermobacter) 		PF07826
(IMP_cyclohyd) 		4 ARG A   5
ILE A 113
VAL A  71
THR A  32
 None
 1.24A 3eigA-1kuuA:
undetectable		 3eigA-1kuuA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mky PROBABLE GTP-BINDING
PROTEIN ENGA

(Thermotoga
maritima) 		PF01926
(MMR_HSR1)
PF14714
(KH_dom-like) 		4 ASP A 347
ARG A 228
ILE A 225
THR A 357
 None
 1.25A 3eigA-1mkyA:
undetectable		 3eigA-1mkyA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mld MALATE DEHYDROGENASE

(Sus scrofa) 		PF00056
(Ldh_1_N)
PF02866
(Ldh_1_C) 		4 ASP A  33
ILE A  12
VAL A  73
THR A 101
 None
 1.18A 3eigA-1mldA:
1.1		 3eigA-1mldA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ms8 TRANS-SIALIDASE

(Trypanosoma
cruzi) 		PF13385
(Laminin_G_3)
PF13859
(BNR_3) 		4 ASP A  96
ARG A  35
ILE A  63
VAL A  66
 DAN  A 700 (-3.3A)
DAN  A 700 (-3.0A)
None
None
 1.17A 3eigA-1ms8A:
undetectable		 3eigA-1ms8A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1nhc POLYGALACTURONASE I

(Aspergillus
niger) 		PF00295
(Glyco_hydro_28) 		4 ASP A 296
ARG A 262
ILE A 293
VAL A 331
 None
SO4  A2711 (-3.1A)
None
None
 1.23A 3eigA-1nhcA:
undetectable		 3eigA-1nhcA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pgs PEPTIDE-N(4)-(N-ACET
YL-BETA-D-GLUCOSAMIN
YL)ASPARAGINE
AMIDASE F

(Elizabethkingia
meningoseptica) 		PF09112
(N-glycanase_N)
PF09113
(N-glycanase_C) 		4 ASP A 102
ILE A  98
VAL A  65
THR A 111
 None
 1.25A 3eigA-1pgsA:
undetectable		 3eigA-1pgsA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qax PROTEIN
(3-HYDROXY-3-METHYLG
LUTARYL-COENZYME A
REDUCTASE)

(Pseudomonas
mevalonii) 		PF00368
(HMG-CoA_red) 		4 ASP A 158
ILE A 138
VAL A 116
THR A 163
 None
 1.01A 3eigA-1qaxA:
undetectable		 3eigA-1qaxA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qni NITROUS-OXIDE
REDUCTASE

(Marinobacter
hydrocarbonoclasticus) 		no annotation 4 ASP A 245
ILE A 243
VAL A 124
THR A 119
 None
 1.20A 3eigA-1qniA:
undetectable		 3eigA-1qniA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1scj SUBTILISIN E

(Bacillus
subtilis) 		PF00082
(Peptidase_S8) 		4 ASP A  32
ILE A  72
VAL A 121
THR A 174
 None
None
None
CA  A 382 (-4.1A)
 1.18A 3eigA-1scjA:
undetectable		 3eigA-1scjA:
19.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1u70 DIHYDROFOLATE
REDUCTASE

(Mus musculus) 		PF00186
(DHFR_1) 		4 ASP A  21
ILE A  60
VAL A 115
THR A 136
 None
MTX  A 187 ( 4.2A)
MTX  A 187 ( 4.0A)
MTX  A 187 (-4.4A)
 0.83A 3eigA-1u70A:
30.3		 3eigA-1u70A:
88.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ve4 ATP
PHOSPHORIBOSYLTRANSF
ERASE

(Thermus
thermophilus) 		PF01634
(HisG) 		4 ASP A 104
ARG A 110
ILE A 108
VAL A 152
 None
 1.08A 3eigA-1ve4A:
undetectable		 3eigA-1ve4A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vh1 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE

(Escherichia
coli) 		PF02348
(CTP_transf_3) 		4 ASP A 100
ILE A 104
VAL A   5
THR A  76
 None
 1.22A 3eigA-1vh1A:
1.6		 3eigA-1vh1A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wpq GLYCEROL-3-PHOSPHATE
DEHYDROGENASE
[NAD+], CYTOPLASMIC

(Homo sapiens) 		PF01210
(NAD_Gly3P_dh_N)
PF07479
(NAD_Gly3P_dh_C) 		4 ASP A 123
ARG A 139
ILE A 136
VAL A  93
 None
 1.20A 3eigA-1wpqA:
undetectable		 3eigA-1wpqA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zpu IRON TRANSPORT
MULTICOPPER OXIDASE
FET3

(Saccharomyces
cerevisiae) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 ASP A 320
ARG A 256
ILE A 251
VAL A 259
 None
 1.24A 3eigA-1zpuA:
undetectable		 3eigA-1zpuA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2afh NITROGENASE
MOLYBDENUM-IRON
PROTEIN

(Azotobacter
vinelandii) 		PF00148
(Oxidored_nitro)
PF11844
(DUF3364) 		4 ASP B 256
ILE B 240
VAL B 291
THR B 301
 None
 1.23A 3eigA-2afhB:
undetectable		 3eigA-2afhB:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b0t NADP ISOCITRATE
DEHYDROGENASE

(Corynebacterium
glutamicum) 		PF03971
(IDH) 		4 ARG A  38
ILE A  40
VAL A 135
THR A  73
 None
 1.02A 3eigA-2b0tA:
2.1		 3eigA-2b0tA:
13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bgh VINORINE SYNTHASE

(Rauvolfia
serpentina) 		PF02458
(Transferase) 		4 ASP A 303
ILE A 257
VAL A 272
THR A 319
 None
 1.21A 3eigA-2bghA:
undetectable		 3eigA-2bghA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dvm 439AA LONG
HYPOTHETICAL MALATE
OXIDOREDUCTASE

(Pyrococcus
horikoshii) 		PF00390
(malic)
PF03949
(Malic_M) 		4 ASP A  71
ARG A  74
ILE A  81
VAL A  89
 None
NAD  A2503 ( 4.4A)
None
None
 1.17A 3eigA-2dvmA:
undetectable		 3eigA-2dvmA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i14 NICOTINATE-NUCLEOTID
E PYROPHOSPHORYLASE

(Pyrococcus
furiosus) 		PF01729
(QRPTase_C)
PF02749
(QRPTase_N) 		4 ASP A 148
ILE A 292
VAL A 131
THR A 175
 None
 1.19A 3eigA-2i14A:
undetectable		 3eigA-2i14A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jeo URIDINE-CYTIDINE
KINASE 1

(Homo sapiens) 		PF00485
(PRK) 		4 ASP A  65
ILE A  61
VAL A  28
THR A 160
 None
 1.10A 3eigA-2jeoA:
2.2		 3eigA-2jeoA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jzn MANNOSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT

(Escherichia
coli) 		PF03610
(EIIA-man) 		4 ASP A  83
ARG A  79
ILE A  80
VAL A  89
 None
 1.08A 3eigA-2jznA:
undetectable		 3eigA-2jznA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oqh PUTATIVE ISOMERASE

(Streptomyces
coelicolor) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ASP A 218
ILE A 241
VAL A 196
THR A 131
 None
 1.16A 3eigA-2oqhA:
undetectable		 3eigA-2oqhA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2own PUTATIVE
OLEOYL-[ACYL-CARRIER
PROTEIN]
THIOESTERASE

(Lactobacillus
plantarum) 		PF01643
(Acyl-ACP_TE) 		4 ASP A 185
ILE A  34
VAL A 206
THR A 235
 None
 1.10A 3eigA-2ownA:
undetectable		 3eigA-2ownA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p8v HOMER PROTEIN
HOMOLOG 3

(Homo sapiens) 		PF00568
(WH1) 		4 ASP A  85
ARG A  52
ILE A  53
VAL A 112
 None
 1.23A 3eigA-2p8vA:
undetectable		 3eigA-2p8vA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pff FATTY ACID SYNTHASE
SUBUNIT ALPHA

(Saccharomyces
cerevisiae) 		PF00106
(adh_short)
PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C) 		5 ASP A1391
ARG A1017
ILE A1319
VAL A1404
THR A1528
 None
 1.46A 3eigA-2pffA:
undetectable		 3eigA-2pffA:
11.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vvt GLUTAMATE RACEMASE

(Enterococcus
faecalis) 		PF01177
(Asp_Glu_race) 		4 ARG A 102
ILE A  97
VAL A 115
THR A 108
 None
 1.14A 3eigA-2vvtA:
3.1		 3eigA-2vvtA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w40 GLYCEROL KINASE,
PUTATIVE

(Plasmodium
falciparum) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ASP A 181
ARG A 187
VAL A  86
THR A  11
 None
None
EDO  A1510 (-4.6A)
GOL  A1511 ( 4.8A)
 1.09A 3eigA-2w40A:
undetectable		 3eigA-2w40A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2yuo RUN AND TBC1 DOMAIN
CONTAINING 3

(Mus musculus) 		PF00018
(SH3_1) 		4 ASP A  63
ARG A   9
ILE A  34
VAL A  59
 None
 1.17A 3eigA-2yuoA:
undetectable		 3eigA-2yuoA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zpb NITRILE HYDRATASE
SUBUNIT ALPHA
NITRILE HYDRATASE
SUBUNIT BETA

(Rhodococcus
erythropolis) 		PF02211
(NHase_beta)
PF02979
(NHase_alpha) 		4 ASP A 161
ARG A 167
ILE A 107
THR B 157
 None
CSO  A 114 ( 3.8A)
None
None
 1.15A 3eigA-2zpbA:
undetectable		 3eigA-2zpbA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ai5 YEAST ENHANCED GREEN
FLUORESCENT
PROTEIN,UBIQUITIN

(Aequorea
victoria;
Mus musculus) 		PF00240
(ubiquitin)
PF01353
(GFP) 		4 ASP A 180
ARG A 168
ILE A 167
VAL A 150
 None
 1.12A 3eigA-3ai5A:
undetectable		 3eigA-3ai5A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b13 DEDICATOR OF
CYTOKINESIS PROTEIN
2

(Homo sapiens) 		PF06920
(DHR-2) 		4 ASP A1341
ARG A1480
VAL A1345
THR A1471
 None
 1.24A 3eigA-3b13A:
undetectable		 3eigA-3b13A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ckn PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
avium) 		PF00535
(Glycos_transf_2) 		4 ASP A  68
ARG A  95
ILE A  63
VAL A 103
 None
 1.20A 3eigA-3cknA:
1.5		 3eigA-3cknA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cnn PUTATIVE
UNCHARACTERIZED
PROTEIN

(Thermotoga
maritima) 		PF01926
(MMR_HSR1) 		4 ASP A 250
ARG A 194
ILE A 191
VAL A 243
 None
 1.08A 3eigA-3cnnA:
2.2		 3eigA-3cnnA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cpr DIHYDRODIPICOLINATE
SYNTHETASE

(Corynebacterium
glutamicum) 		PF00701
(DHDPS) 		4 ASP A 177
ILE A 158
VAL A 117
THR A  59
 None
None
None
MCL  A 176 ( 3.9A)
 1.03A 3eigA-3cprA:
undetectable		 3eigA-3cprA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e74 ALLANTOINASE

(Escherichia
coli) 		PF01979
(Amidohydro_1) 		4 ARG A 428
ILE A 448
VAL A  56
THR A 425
 None
 1.23A 3eigA-3e74A:
undetectable		 3eigA-3e74A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ehf SENSOR KINASE (YOCF
PROTEIN)

(Bacillus
subtilis) 		PF07730
(HisKA_3) 		4 ASP A 321
ARG A 304
VAL A 291
THR A 362
 None
 1.23A 3eigA-3ehfA:
undetectable		 3eigA-3ehfA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i04 CARBON MONOXIDE
DEHYDROGENASE/ACETYL
-COA SYNTHASE
SUBUNIT BETA

(Moorella
thermoacetica) 		PF03063
(Prismane) 		4 ASP A 570
ILE A 190
VAL A 557
THR A 602
 None
 0.92A 3eigA-3i04A:
undetectable		 3eigA-3i04A:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k32 UNCHARACTERIZED
PROTEIN MJ0690

(Methanocaldococcus
jannaschii) 		no annotation 4 ASP A 165
ARG A 171
ILE A 170
VAL A  39
 None
 0.94A 3eigA-3k32A:
undetectable		 3eigA-3k32A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kjr DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE

(Babesia bovis) 		PF00186
(DHFR_1)
PF00303
(Thymidylat_synt) 		4 ASP A 492
ARG A 280
ILE A 283
VAL A 496
 None
 1.19A 3eigA-3kjrA:
22.1		 3eigA-3kjrA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lua RESPONSE REGULATOR
RECEIVER PROTEIN

(Ruminiclostridium
thermocellum) 		PF00072
(Response_reg) 		4 ASP A   2
ILE A  25
VAL A 122
THR A  80
 None
 1.24A 3eigA-3luaA:
undetectable		 3eigA-3luaA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwn KINESIN-LIKE PROTEIN
KIF9

(Homo sapiens) 		PF00225
(Kinesin) 		4 ASP A 245
ARG A  12
ILE A 115
VAL A 312
 MG  A 402 ( 4.0A)
ADP  A 401 (-3.5A)
None
None
 1.22A 3eigA-3nwnA:
undetectable		 3eigA-3nwnA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3on9 TUMOUR NECROSIS
FACTOR RECEPTOR

(Ectromelia
virus) 		PF07190
(DUF1406) 		4 ASP A 167
ILE A 170
VAL A 270
THR A 258
 None
 1.08A 3eigA-3on9A:
undetectable		 3eigA-3on9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3on9 TUMOUR NECROSIS
FACTOR RECEPTOR

(Ectromelia
virus) 		PF07190
(DUF1406) 		4 ASP A 167
ILE A 170
VAL A 270
THR A 259
 None
 1.14A 3eigA-3on9A:
undetectable		 3eigA-3on9A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3owc PROBABLE
ACETYLTRANSFERASE

(Pseudomonas
aeruginosa) 		PF00583
(Acetyltransf_1) 		4 ARG A  96
ILE A  97
VAL A 133
THR A 159
 EDO  A 187 (-3.5A)
None
COA  A2598 ( 4.5A)
None
 1.25A 3eigA-3owcA:
undetectable		 3eigA-3owcA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p28 GREEN FLUORESCENT
PROTEIN

(Aequorea
victoria) 		PF01353
(GFP) 		4 ASP A 132
ARG A 120
ILE A 119
VAL A 102
 None
 1.07A 3eigA-3p28A:
undetectable		 3eigA-3p28A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p8c NCK-ASSOCIATED
PROTEIN 1

(Homo sapiens) 		PF09735
(Nckap1) 		4 ASP B 538
ARG B 297
ILE B 541
THR B 139
 None
 1.12A 3eigA-3p8cB:
undetectable		 3eigA-3p8cB:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3r1j ALPHA-KETOGLUTARATE-
DEPENDENT TAURINE
DIOXYGENASE

(Mycobacterium
avium) 		PF02668
(TauD) 		4 ARG A 268
ILE A 269
VAL A 243
THR A 126
 None
 1.20A 3eigA-3r1jA:
undetectable		 3eigA-3r1jA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ram HMRA PROTEIN

(Staphylococcus
aureus) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ASP A  50
ILE A 107
VAL A 122
THR A  55
 None
None
None
GOL  A 501 (-4.3A)
 1.14A 3eigA-3ramA:
undetectable		 3eigA-3ramA:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rmj 2-ISOPROPYLMALATE
SYNTHASE

(Neisseria
meningitidis) 		PF00682
(HMGL-like) 		4 ASP A  11
ILE A 246
VAL A   7
THR A 167
 None
 1.19A 3eigA-3rmjA:
undetectable		 3eigA-3rmjA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3suc PRENECK APPENDAGE
PROTEIN

(Bacillus virus
phi29) 		PF11962
(Peptidase_G2)
PF12708
(Pectate_lyase_3) 		4 ARG A 807
ILE A 808
VAL A 851
THR A 734
 None
 1.23A 3eigA-3sucA:
undetectable		 3eigA-3sucA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tlm SARCOPLASMIC/ENDOPLA
SMIC RETICULUM
CALCIUM ATPASE 1

(Bos taurus) 		PF00122
(E1-E2_ATPase)
PF00689
(Cation_ATPase_C)
PF00690
(Cation_ATPase_N)
PF08282
(Hydrolase_3)
PF13246
(Cation_ATPase) 		4 ASP A 426
ILE A 140
VAL A 151
THR A  21
 None
 1.19A 3eigA-3tlmA:
undetectable		 3eigA-3tlmA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3whi SUBTILISIN E

(Bacillus
subtilis) 		PF00082
(Peptidase_S8)
PF05922
(Inhibitor_I9) 		4 ASP A 122
ILE A 162
VAL A 211
THR A 264
 None
 1.21A 3eigA-3whiA:
undetectable		 3eigA-3whiA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cad RAS AND A-FACTOR
CONVERTING ENZYME 1,
RCE1

(Methanococcus
maripaludis) 		PF02517
(Abi) 		4 ASP C 150
ARG C 145
ILE C 220
THR C  16
 None
 1.25A 3eigA-4cadC:
undetectable		 3eigA-4cadC:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4cua BETA-GALACTOSIDASE

(Streptococcus
pneumoniae) 		no annotation 4 ARG A1621
ILE A1620
VAL A1638
THR A1633
 EDO  A2646 (-3.8A)
None
None
None
 1.18A 3eigA-4cuaA:
undetectable		 3eigA-4cuaA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e1j GLYCEROL KINASE

(Sinorhizobium
meliloti) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		4 ASP A 204
ARG A 210
VAL A 108
THR A  35
 None
None
None
GOL  A 601 ( 4.9A)
 1.05A 3eigA-4e1jA:
undetectable		 3eigA-4e1jA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4htg PORPHOBILINOGEN
DEAMINASE,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF01379
(Porphobil_deam)
PF03900
(Porphobil_deamC) 		4 ASP A 221
ARG A  14
ILE A  13
VAL A  90
 None
 1.24A 3eigA-4htgA:
undetectable		 3eigA-4htgA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kgk THG1-LIKE
UNCHARACTERIZED
PROTEIN

(Bacillus
thuringiensis) 		PF04446
(Thg1) 		4 ASP A  75
ARG A  28
ILE A  29
VAL A  70
 MG  A 302 (-2.8A)
None
None
None
 1.25A 3eigA-4kgkA:
undetectable		 3eigA-4kgkA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kzk L-ARABINOSE ABC
TRANSPORTER,
PERIPLASMIC
L-ARABINOSE-BINDING
PROTEIN

(Burkholderia
thailandensis) 		PF00532
(Peripla_BP_1) 		4 ASP A 132
ILE A 104
VAL A  91
THR A 294
 None
 1.20A 3eigA-4kzkA:
1.6		 3eigA-4kzkA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mzd NISIN LEADER
PEPTIDE-PROCESSING
SERINE PROTEASE NISP

(Lactococcus
lactis) 		PF00082
(Peptidase_S8) 		4 ASP A 465
ILE A 467
VAL A 402
THR A 395
 None
 1.15A 3eigA-4mzdA:
undetectable		 3eigA-4mzdA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qwv HIGH-AFFINITY
LEUCINE-SPECIFIC
TRANSPORT SYSTEM
PERIPLASMIC BINDING
PROTEIN, CHEMOTAXIS
PROTEIN CHEY

(Escherichia
coli;
Thermotoga
maritima) 		PF00072
(Response_reg)
PF13458
(Peripla_BP_6) 		4 ASP A 247
ILE A 253
VAL A 269
THR A 117
 None
 1.20A 3eigA-4qwvA:
undetectable		 3eigA-4qwvA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rv0 TRANSITIONAL
ENDOPLASMIC
RETICULUM ATPASE
TER94

(Drosophila
melanogaster) 		PF02359
(CDC48_N)
PF02933
(CDC48_2) 		4 ARG A 141
ILE A  67
VAL A 105
THR A 177
 None
 1.25A 3eigA-4rv0A:
undetectable		 3eigA-4rv0A:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uar PROTEIN CBBY

(Rhodobacter
sphaeroides) 		PF13419
(HAD_2) 		4 ASP A 139
ILE A 109
VAL A 172
THR A  12
 None
 1.11A 3eigA-4uarA:
2.8		 3eigA-4uarA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wji PUTATIVE
CYCLOHEXADIENYL
DEHYDROGENASE AND
ADH PREPHENATE
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF02153
(PDH) 		4 ASP A  53
ILE A  24
VAL A  70
THR A  37
 None
None
None
NAP  A 301 (-3.1A)
 1.07A 3eigA-4wjiA:
1.4		 3eigA-4wjiA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wxj GLUTAMATE RECEPTOR
IIB,GLUTAMATE
RECEPTOR IIB

(Drosophila
melanogaster) 		PF10613
(Lig_chan-Glu_bd) 		4 ASP A  79
ARG A  16
ILE A  81
THR A 150
 None
None
None
GLU  A 301 (-3.5A)
 1.19A 3eigA-4wxjA:
undetectable		 3eigA-4wxjA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xcg THERMOSOME SUBUNIT
BETA

(Sulfolobus
solfataricus) 		PF00118
(Cpn60_TCP1) 		4 ASP B 252
ILE B 345
VAL B 300
THR B 337
 None
 1.18A 3eigA-4xcgB:
undetectable		 3eigA-4xcgB:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ysh GLYCINE OXIDASE

(Geobacillus
kaustophilus) 		PF01266
(DAO) 		4 ARG A 288
ILE A 264
VAL A 293
THR A 100
 SO4  A 402 (-3.0A)
None
None
None
 1.21A 3eigA-4yshA:
undetectable		 3eigA-4yshA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5anb ELONGATION FACTOR TU
GTP-BINDING
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF00009
(GTP_EFTU)
PF00679
(EFG_C)
PF14492
(EFG_II) 		4 ASP K  58
ILE K  68
VAL K  97
THR K 105
 None
 1.15A 3eigA-5anbK:
undetectable		 3eigA-5anbK:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aor DOSAGE COMPENSATION
REGULATOR

(Drosophila
melanogaster) 		PF00270
(DEAD)
PF00271
(Helicase_C)
PF04408
(HA2)
PF07717
(OB_NTP_bind) 		4 ASP A 507
ILE A 417
VAL A 403
THR A 544
 MG  A2160 (-3.6A)
None
None
None
 0.71A 3eigA-5aorA:
undetectable		 3eigA-5aorA:
8.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dum 65C6 HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		4 ASP H  55
ARG H  50
ILE H  58
VAL H  79
 None
 0.93A 3eigA-5dumH:
undetectable		 3eigA-5dumH:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ey9 LONG-CHAIN-FATTY-ACI
D--AMP LIGASE FADD32

(Mycobacterium
marinum) 		PF00501
(AMP-binding) 		4 ASP A 584
ILE A 570
VAL A 515
THR A 592
 None
 0.98A 3eigA-5ey9A:
undetectable		 3eigA-5ey9A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fgu GREEN FLUORESCENT
PROTEIN,EXTRACELLULA
R STREPTODORNASE D

(Aequorea
victoria;
Streptococcus
pyogenes) 		PF01353
(GFP)
PF13930
(Endonuclea_NS_2) 		4 ASP A 180
ARG A 168
ILE A 167
VAL A 150
 None
 1.25A 3eigA-5fguA:
undetectable		 3eigA-5fguA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fn4 NICASTRIN

(Homo sapiens) 		PF05450
(Nicastrin) 		4 ASP A 443
ILE A 463
VAL A 303
THR A 492
 None
 0.79A 3eigA-5fn4A:
undetectable		 3eigA-5fn4A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5giu PROLINE DIPEPTIDASE

(Deinococcus
radiodurans) 		PF00557
(Peptidase_M24)
PF01321
(Creatinase_N) 		4 ASP A 203
ARG A 154
ILE A 201
VAL A 226
 None
 1.20A 3eigA-5giuA:
undetectable		 3eigA-5giuA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i3e PUTATIVE
DEOXYRIBONUCLEASE-2

(Burkholderia
thailandensis) 		PF03265
(DNase_II) 		4 ASP A 108
ARG A 170
VAL A 104
THR A 184
 None
 1.16A 3eigA-5i3eA:
undetectable		 3eigA-5i3eA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iuf BIFUNCTIONAL
OLIGORIBONUCLEASE
AND PAP PHOSPHATASE
NRNA

(Bacillus
subtilis) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 ARG A  19
ILE A  87
VAL A  76
THR A  35
 None
 1.17A 3eigA-5iufA:
undetectable		 3eigA-5iufA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iuf BIFUNCTIONAL
OLIGORIBONUCLEASE
AND PAP PHOSPHATASE
NRNA

(Bacillus
subtilis) 		PF01368
(DHH)
PF02272
(DHHA1) 		4 ASP A 102
ILE A  87
VAL A  76
THR A  35
 None
 1.08A 3eigA-5iufA:
undetectable		 3eigA-5iufA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jtw COMPLEMENT C4-A

(Homo sapiens) 		PF00207
(A2M)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		4 ASP B1029
ILE B1049
VAL B1085
THR B1305
 None
 1.08A 3eigA-5jtwB:
undetectable		 3eigA-5jtwB:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ket ALDO-KETO REDUCTASE
1

(Coptotermes
gestroi) 		PF00248
(Aldo_ket_red) 		4 ARG A 183
ILE A 173
VAL A 211
THR A   9
 None
 1.07A 3eigA-5ketA:
undetectable		 3eigA-5ketA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3x NEGATIVE ELONGATION
FACTOR C/D

(Homo sapiens) 		PF04858
(TH1) 		4 ASP B 321
ILE B 378
VAL B 325
THR B 285
 None
 1.18A 3eigA-5l3xB:
undetectable		 3eigA-5l3xB:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5m0k BETA-XYLANASE

(Cellulomonas
flavigena) 		no annotation 4 ASP A  39
ARG A  14
ILE A 262
VAL A 295
 None
 1.24A 3eigA-5m0kA:
undetectable		 3eigA-5m0kA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nn8 LYSOSOMAL
ALPHA-GLUCOSIDASE

(Homo sapiens) 		no annotation 4 ASP A 645
ILE A 598
VAL A 400
THR A 384
 None
 1.08A 3eigA-5nn8A:
undetectable		 3eigA-5nn8A:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5o1m RUBBER OXYGENASE

(Streptomyces
sp. K30) 		PF09995
(DUF2236) 		4 ARG A 147
ILE A 222
VAL A 152
THR A 297
 None
HEM  A 600 ( 4.1A)
HEM  A 600 ( 4.6A)
None
 1.17A 3eigA-5o1mA:
undetectable		 3eigA-5o1mA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oar BETA-HEXOSAMINIDASE

(Aspergillus
oryzae) 		no annotation 4 ASP B 271
ILE B 400
VAL B 382
THR B 320
 None
 1.19A 3eigA-5oarB:
undetectable		 3eigA-5oarB:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ot0 L-ASPARAGINASE

(Thermococcus
kodakarensis) 		no annotation 4 ASP A  48
ILE A  30
VAL A  80
THR A  91
 None
 1.22A 3eigA-5ot0A:
undetectable		 3eigA-5ot0A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5td7 ZGC:55652

(Danio rerio) 		PF00850
(Hist_deacetyl) 		4 ARG A 463
ILE A 437
VAL A 445
THR A 457
 None
 1.21A 3eigA-5td7A:
undetectable		 3eigA-5td7A:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tla UBIQUITIN-LIKE
PROTEIN ISG15

(Mus musculus) 		PF00240
(ubiquitin) 		4 ASP A  54
ARG A  44
VAL A  38
THR A  99
 None
 1.12A 3eigA-5tlaA:
undetectable		 3eigA-5tlaA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x49 PROBABLE XAA-PRO
AMINOPEPTIDASE 3

(Homo sapiens) 		PF00557
(Peptidase_M24)
PF05195
(AMP_N) 		4 ASP A 118
ILE A 240
VAL A  97
THR A 223
 None
 0.86A 3eigA-5x49A:
undetectable		 3eigA-5x49A:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmj FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT

(Desulfovibrio
gigas) 		no annotation 4 ARG A 273
ILE A 330
VAL A 345
THR A 227
 None
None
None
FAD  A 701 (-4.9A)
 1.25A 3eigA-5xmjA:
undetectable		 3eigA-5xmjA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xnz CRED

(Streptomyces
cremeus) 		no annotation 4 ASP A 131
ARG A 185
ILE A 126
VAL A 249
 None
FUM  A 502 (-3.2A)
None
None
 1.23A 3eigA-5xnzA:
undetectable		 3eigA-5xnzA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y3r X-RAY REPAIR
CROSS-COMPLEMENTING
PROTEIN 5

(Homo sapiens) 		PF02735
(Ku)
PF03730
(Ku_C)
PF03731
(Ku_N) 		4 ASP B 398
ARG B 250
ILE B 261
VAL B 393
 None
 1.20A 3eigA-5y3rB:
undetectable		 3eigA-5y3rB:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c7v -

(-) 		no annotation 4 ASP A  85
ARG A  59
VAL A  79
THR A  53
 None
 1.20A 3eigA-6c7vA:
undetectable		 3eigA-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6co7 PREDICTED PROTEIN

(Nematostella
vectensis) 		no annotation 4 ASP A 119
ILE A 274
VAL A 256
THR A  92
 None
 1.25A 3eigA-6co7A:
1.4		 3eigA-6co7A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6dfp VCA0883

(Vibrio cholerae) 		no annotation 4 ASP A 340
ILE A  91
VAL A 330
THR A 301
 None
 1.19A 3eigA-6dfpA:
undetectable		 3eigA-6dfpA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ewp CENTROSOMAL PROTEIN
OF 120 KDA

(Mus musculus) 		no annotation 4 ASP A 598
ILE A 596
VAL A 475
THR A 494
 None
 1.11A 3eigA-6ewpA:
undetectable		 3eigA-6ewpA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fi2 VEXL

(Achromobacter
denitrificans) 		no annotation 4 ASP A 165
ARG A 168
VAL A 196
THR A 147
 None
 1.14A 3eigA-6fi2A:
undetectable		 3eigA-6fi2A:
15.59