SIMILAR PATTERNS OF AMINO ACIDS FOR 3EEY_D_SAMD300_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1b4p PROTEIN (GLUTATHIONE
S-TRANSFERASE)

(Rattus
norvegicus) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 ASN A  73
ASP A 161
GLN A 165
 None
 0.82A 3eeyD-1b4pA:
undetectable		 3eeyD-1b4pA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1cmz PROTEIN (GAIP
(G-ALPHA
INTERACTING)
PROTEIN)

(Homo sapiens) 		PF00615
(RGS) 		3 ASN A 166
ASP A 179
GLN A 183
 None
 0.77A 3eeyD-1cmzA:
undetectable		 3eeyD-1cmzA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1f59 IMPORTIN BETA-1

(Homo sapiens) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		3 ASN A  63
ASP A 160
GLN A 159
 None
 0.72A 3eeyD-1f59A:
undetectable		 3eeyD-1f59A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fig IGG1-KAPPA 1F7 FAB
(HEAVY CHAIN)

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ASN H  60
ASP H  86
GLN H  83
 None
 0.83A 3eeyD-1figH:
undetectable		 3eeyD-1figH:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gq8 PECTINESTERASE

(Daucus carota) 		PF01095
(Pectinesterase) 		3 ASN A 183
ASP A 136
GLN A 113
 None
CAC  A 501 (-3.2A)
CAC  A 501 ( 4.8A)
 0.83A 3eeyD-1gq8A:
undetectable		 3eeyD-1gq8A:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h71 SERRALYSIN

(Pseudomonas sp.
'TAC II 18') 		PF00413
(Peptidase_M10)
PF08548
(Peptidase_M10_C) 		3 ASN P 334
ASP P 397
GLN P 393
 None
CA  P 501 (-2.6A)
CA  P 501 (-3.6A)
 0.75A 3eeyD-1h71P:
undetectable		 3eeyD-1h71P:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h7k CATALASE

(Proteus
mirabilis) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 ASN A 223
ASP A 178
GLN A 174
 None
 0.73A 3eeyD-1h7kA:
undetectable		 3eeyD-1h7kA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1i2o TRANSALDOLASE B

(Escherichia
coli) 		PF00923
(TAL_FSA) 		3 ASN A 152
ASP A  31
GLN A  30
 None
 0.76A 3eeyD-1i2oA:
undetectable		 3eeyD-1i2oA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iqc DI-HEME PEROXIDASE

(Nitrosomonas
europaea) 		PF00034
(Cytochrom_C)
PF03150
(CCP_MauG) 		3 ASN A 268
ASP A 170
GLN A 169
 None
 0.81A 3eeyD-1iqcA:
undetectable		 3eeyD-1iqcA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pby QUINOHEMOPROTEIN
AMINE DEHYDROGENASE
60 KDA SUBUNIT
QUINOHEMOPROTEIN
AMINE DEHYDROGENASE
9 KDA SUBUNIT

(Paracoccus
denitrificans;
Paracoccus
denitrificans) 		PF09098
(Dehyd-heme_bind)
PF09099
(Qn_am_d_aIII)
PF09100
(Qn_am_d_aIV)
PF14930
(Qn_am_d_aII)
PF08992
(QH-AmDH_gamma) 		3 ASN C  56
ASP C  49
GLN A 129
 None
 0.73A 3eeyD-1pbyC:
undetectable		 3eeyD-1pbyC:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qgr PROTEIN (IMPORTIN
BETA SUBUNIT)

(Homo sapiens) 		PF03810
(IBN_N)
PF13513
(HEAT_EZ) 		3 ASN A  63
ASP A 160
GLN A 159
 None
 0.84A 3eeyD-1qgrA:
undetectable		 3eeyD-1qgrA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vf8 SECRETORY PROTEIN

(Mus musculus) 		PF00704
(Glyco_hydro_18) 		3 ASN A  24
ASP A  55
GLN A  51
 None
 0.72A 3eeyD-1vf8A:
undetectable		 3eeyD-1vf8A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zr6 GLUCOOLIGOSACCHARIDE
OXIDASE

(Sarocladium
strictum) 		PF01565
(FAD_binding_4)
PF08031
(BBE) 		3 ASN A  30
ASP A 431
GLN A 408
 None
 0.84A 3eeyD-1zr6A:
undetectable		 3eeyD-1zr6A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b24 NAPHTHALENE
DIOXYGENASE LARGE
SUBUNIT

(Rhodococcus sp.
NCIMB 12038) 		PF00355
(Rieske)
PF00848
(Ring_hydroxyl_A) 		3 ASN A 375
ASP A 208
GLN A 424
 None
 0.79A 3eeyD-2b24A:
undetectable		 3eeyD-2b24A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cde INKT-TCR

(Homo sapiens) 		PF07686
(V-set)
PF09291
(DUF1968) 		3 ASN A  59
ASP A  84
GLN A  81
 None
 0.71A 3eeyD-2cdeA:
undetectable		 3eeyD-2cdeA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d4y FLAGELLAR
HOOK-ASSOCIATED
PROTEIN 1

(Salmonella
enterica) 		no annotation 3 ASN A 158
ASP A 152
GLN A 148
 None
 0.77A 3eeyD-2d4yA:
undetectable		 3eeyD-2d4yA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fb6 CONSERVED
HYPOTHETICAL PROTEIN

(Bacteroides
thetaiotaomicron) 		PF02635
(DrsE) 		3 ASN A  15
ASP A  54
GLN A  56
 None
 0.78A 3eeyD-2fb6A:
undetectable		 3eeyD-2fb6A:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fnc MALTOSE ABC
TRANSPORTER,
PERIPLASMIC
MALTOSE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF13416
(SBP_bac_8) 		3 ASN A 230
ASP A 301
GLN A  15
 None
None
MLR  A2913 ( 3.9A)
 0.79A 3eeyD-2fncA:
undetectable		 3eeyD-2fncA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g0t CONSERVED
HYPOTHETICAL PROTEIN

(Thermotoga
maritima) 		PF07755
(DUF1611)
PF17396
(DUF1611_N) 		3 ASN A  87
ASP A 210
GLN A 241
 None
None
EDO  A 341 (-3.1A)
 0.83A 3eeyD-2g0tA:
4.8		 3eeyD-2g0tA:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gjx BETA-HEXOSAMINIDASE
ALPHA CHAIN

(Homo sapiens) 		PF00728
(Glyco_hydro_20)
PF14845
(Glycohydro_20b2) 		3 ASN A 199
ASP A 163
GLN A  28
 None
 0.78A 3eeyD-2gjxA:
undetectable		 3eeyD-2gjxA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gk1 BETA-HEXOSAMINIDASE
SUBUNIT ALPHA
BETA-HEXOSAMINIDASE
SUBUNIT ALPHA

(Homo sapiens;
Homo sapiens) 		PF00728
(Glyco_hydro_20)
PF14845
(Glycohydro_20b2)
no annotation 		3 ASN I 199
ASP I 163
GLN A  28
 None
 0.84A 3eeyD-2gk1I:
undetectable		 3eeyD-2gk1I:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ipc PREPROTEIN
TRANSLOCASE SECA
SUBUNIT

(Thermus
thermophilus) 		PF01043
(SecA_PP_bind)
PF07516
(SecA_SW)
PF07517
(SecA_DEAD) 		3 ASN A 176
ASP A 212
GLN A 677
 None
 0.78A 3eeyD-2ipcA:
2.6		 3eeyD-2ipcA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j7a CYTOCHROME C NITRITE
REDUCTASE NRFA

(Desulfovibrio
vulgaris) 		PF02335
(Cytochrom_C552) 		3 ASN A  83
ASP A 127
GLN A 126
 None
HEM  A1003 (-3.5A)
None
 0.83A 3eeyD-2j7aA:
undetectable		 3eeyD-2j7aA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jf4 PERIPLASMIC
TREHALASE

(Escherichia
coli) 		PF01204
(Trehalase) 		3 ASN A  69
ASP A  78
GLN A  82
 None
 0.70A 3eeyD-2jf4A:
undetectable		 3eeyD-2jf4A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7z HEAT SHOCK COGNATE
71 KDA PROTEIN

(Rattus
norvegicus) 		PF00012
(HSP70) 		3 ASN A 168
ASP A 160
GLN A 156
 None
 0.77A 3eeyD-2v7zA:
undetectable		 3eeyD-2v7zA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xn1 ALPHA-GALACTOSIDASE

(Lactobacillus
acidophilus) 		PF02065
(Melibiase)
PF16874
(Glyco_hydro_36C)
PF16875
(Glyco_hydro_36N) 		3 ASN A 260
ASP A 538
GLN A 541
 None
 0.46A 3eeyD-2xn1A:
undetectable		 3eeyD-2xn1A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zkm 1-PHOSPHATIDYLINOSIT
OL-4,5-BISPHOSPHATE
PHOSPHODIESTERASE
BETA-2

(Homo sapiens) 		PF00168
(C2)
PF00387
(PI-PLC-Y)
PF00388
(PI-PLC-X)
PF09279
(EF-hand_like) 		3 ASN X  92
ASP X  83
GLN X  79
 None
 0.73A 3eeyD-2zkmX:
undetectable		 3eeyD-2zkmX:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a0f XYLOGLUCANASE

(Geotrichum sp.
M128) 		no annotation 3 ASN A 308
ASP A 258
GLN A 235
 None
 0.78A 3eeyD-3a0fA:
undetectable		 3eeyD-3a0fA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bxz PREPROTEIN
TRANSLOCASE SUBUNIT
SECA

(Escherichia
coli) 		PF07517
(SecA_DEAD) 		3 ASN A 179
ASP A 212
GLN A 570
 None
 0.80A 3eeyD-3bxzA:
2.1		 3eeyD-3bxzA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c5w PP2A A SUBUNIT

(Homo sapiens) 		PF02985
(HEAT)
PF13646
(HEAT_2) 		3 ASN A 535
ASP A 570
GLN A 571
 None
 0.66A 3eeyD-3c5wA:
undetectable		 3eeyD-3c5wA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cgg SAM-DEPENDENT
METHYLTRANSFERASE

(Corynebacterium
glutamicum) 		PF13649
(Methyltransf_25) 		3 ASN A  24
ASP A  86
GLN A  85
 None
 0.65A 3eeyD-3cggA:
14.1		 3eeyD-3cggA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dbo UNCHARACTERIZED
PROTEIN
UNCHARACTERIZED
PROTEIN

(Mycobacterium
tuberculosis;
Mycobacterium
tuberculosis) 		PF02604
(PhdYeFM_antitox)
PF01850
(PIN) 		3 ASN A  76
ASP B 133
GLN B 132
 None
 0.74A 3eeyD-3dboA:
undetectable		 3eeyD-3dboA:
19.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3eey PUTATIVE RRNA
METHYLASE

(Ruminiclostridium
thermocellum) 		PF06962
(rRNA_methylase) 		3 ASN A  33
ASP A  52
GLN A  54
 SAM  A 300 (-4.0A)
SAM  A 300 (-2.9A)
SAM  A 300 (-3.8A)
 0.02A 3eeyD-3eeyA:
36.2		 3eeyD-3eeyA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gtu GLUTATHIONE
S-TRANSFERASE

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 ASN B  77
ASP B 165
GLN B 169
 None
 0.82A 3eeyD-3gtuB:
undetectable		 3eeyD-3gtuB:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h0g DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Schizosaccharomyces
pombe) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		3 ASN B 191
ASP B 454
GLN B 455
 None
 0.81A 3eeyD-3h0gB:
undetectable		 3eeyD-3h0gB:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hbu SECRETED PROTEASE C

(Dickeya
chrysanthemi) 		PF00353
(HemolysinCabind)
PF00413
(Peptidase_M10)
PF08548
(Peptidase_M10_C) 		3 ASN P 349
ASP P 412
GLN P 408
 None
CA  P 485 (-2.7A)
CA  P 485 (-3.5A)
 0.80A 3eeyD-3hbuP:
undetectable		 3eeyD-3hbuP:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hvy CYSTATHIONINE
BETA-LYASE FAMILY
PROTEIN, YNBB
B.SUBTILIS ORTHOLOG

(Clostridium
acetobutylicum) 		PF06838
(Met_gamma_lyase) 		3 ASN A  99
ASP A 217
GLN A 182
 LLP  A 243 ( 3.3A)
LLP  A 243 ( 2.9A)
LLP  A 243 ( 4.0A)
 0.83A 3eeyD-3hvyA:
5.5		 3eeyD-3hvyA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3iab RIBONUCLEASES P/MRP
PROTEIN SUBUNIT POP6

(Saccharomyces
cerevisiae) 		PF01918
(Alba) 		3 ASN A 105
ASP A 144
GLN A  77
 None
 0.78A 3eeyD-3iabA:
5.2		 3eeyD-3iabA:
24.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ipc ABC TRANSPORTER,
SUBSTRATE BINDING
PROTEIN (AMINO ACID)

(Agrobacterium
fabrum) 		PF13458
(Peripla_BP_6) 		3 ASN A  78
ASP A 121
GLN A 124
 None
 0.81A 3eeyD-3ipcA:
2.8		 3eeyD-3ipcA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		3 ASN A 480
ASP A 446
GLN A 445
 U  C  36 ( 3.4A)
A  C  35 ( 4.0A)
C  C  65 ( 4.6A)
 0.79A 3eeyD-3jb9A:
undetectable		 3eeyD-3jb9A:
6.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2g RESINIFERATOXIN-BIND
ING,
PHOSPHOTRIESTERASE-R
ELATED PROTEIN

(Rhodobacter
sphaeroides) 		PF02126
(PTE) 		3 ASN A  77
ASP A 270
GLN A 271
 None
None
DTV  A 402 ( 4.0A)
 0.74A 3eeyD-3k2gA:
undetectable		 3eeyD-3k2gA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3lby PUTATIVE
UNCHARACTERIZED
PROTEIN SMU.1697C

(Streptococcus
mutans) 		PF06962
(rRNA_methylase) 		3 ASN A  32
ASP A  48
GLN A  50
 None
SAH  A4630 (-2.9A)
SAH  A4630 (-3.8A)
 0.35A 3eeyD-3lbyA:
30.6		 3eeyD-3lbyA:
44.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mti RRNA METHYLASE

(Streptococcus
thermophilus) 		PF06962
(rRNA_methylase) 		3 ASN A  32
ASP A  48
GLN A  50
 None
 0.33A 3eeyD-3mtiA:
27.0		 3eeyD-3mtiA:
44.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3op7 AMINOTRANSFERASE
CLASS I AND II

(Streptococcus
suis) 		PF00155
(Aminotran_1_2) 		3 ASN A  57
ASP A 259
GLN A 263
 SO4  A 401 ( 3.0A)
None
None
 0.84A 3eeyD-3op7A:
3.9		 3eeyD-3op7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3prl NADP-DEPENDENT
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE

(Bacillus
halodurans) 		PF00171
(Aldedh) 		3 ASN A 482
ASP A 135
GLN A 136
 None
 0.72A 3eeyD-3prlA:
3.9		 3eeyD-3prlA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3q3q ALKALINE PHOSPHATASE

(Sphingomonas
sp. BSAR-1) 		PF01663
(Phosphodiest) 		3 ASN A 280
ASP A 290
GLN A 288
 None
 0.68A 3eeyD-3q3qA:
undetectable		 3eeyD-3q3qA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s29 SUCROSE SYNTHASE 1

(Arabidopsis
thaliana) 		PF00534
(Glycos_transf_1)
PF00862
(Sucrose_synth) 		3 ASN A 143
ASP A 476
GLN A 433
 None
 0.80A 3eeyD-3s29A:
undetectable		 3eeyD-3s29A:
12.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tc1 OCTAPRENYL
PYROPHOSPHATE
SYNTHASE

(Helicobacter
pylori) 		PF00348
(polyprenyl_synt) 		3 ASN A 216
ASP A 201
GLN A 197
 None
 0.80A 3eeyD-3tc1A:
undetectable		 3eeyD-3tc1A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3usz EXO-1,3/1,4-BETA-GLU
CANASE

(Pseudoalteromonas
sp. BB1) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C) 		3 ASN A 566
ASP A 574
GLN A 612
 None
 0.67A 3eeyD-3uszA:
undetectable		 3eeyD-3uszA:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vla EDGP

(Daucus carota) 		PF14541
(TAXi_C)
PF14543
(TAXi_N) 		3 ASN A  99
ASP A  49
GLN A  52
 None
 0.71A 3eeyD-3vlaA:
undetectable		 3eeyD-3vlaA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w1h L-SERYL-TRNA(SEC)
SELENIUM TRANSFERASE

(Aquifex
aeolicus) 		PF03841
(SelA) 		3 ASN A  81
ASP A 284
GLN A 291
 None
LLP  A 285 ( 4.3A)
None
 0.77A 3eeyD-3w1hA:
3.9		 3eeyD-3w1hA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4a5w COMPLEMENT C5

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF01835
(A2M_N)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF07703
(A2M_N_2) 		3 ASN A 242
ASP A 377
GLN A 381
 None
 0.75A 3eeyD-4a5wA:
undetectable		 3eeyD-4a5wA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b90 DIHYDROPYRIMIDINASE-
RELATED PROTEIN 5

(Homo sapiens) 		PF01979
(Amidohydro_1) 		3 ASN A 429
ASP A 353
GLN A 352
 None
 0.71A 3eeyD-4b90A:
undetectable		 3eeyD-4b90A:
16.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4b92 DIHYDROPYRIMIDINASE-
RELATED PROTEIN 5

(Homo sapiens) 		PF01979
(Amidohydro_1) 		3 ASN A 429
ASP A 353
GLN A 352
 None
 0.79A 3eeyD-4b92A:
undetectable		 3eeyD-4b92A:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23

(Arabidopsis
thaliana) 		PF00069
(Pkinase) 		3 ASN A 196
ASP A 154
GLN A 180
 None
 0.81A 3eeyD-4cztA:
undetectable		 3eeyD-4cztA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4drt DE NOVO DESIGNED
SERINE HYDROLASE,
OR89

(synthetic
construct) 		PF00768
(Peptidase_S11)
PF07943
(PBP5_C) 		3 ASN A  81
ASP A 111
GLN A 110
 None
 0.77A 3eeyD-4drtA:
undetectable		 3eeyD-4drtA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e37 CATALASE

(Pseudomonas
aeruginosa) 		PF00199
(Catalase)
PF06628
(Catalase-rel) 		3 ASN A 224
ASP A 179
GLN A 175
 None
 0.76A 3eeyD-4e37A:
undetectable		 3eeyD-4e37A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ei8 PLASMID REPLICATION
PROTEIN REPX

(Bacillus cereus) 		PF00091
(Tubulin) 		3 ASN A 202
ASP A  59
GLN A  58
 None
 0.72A 3eeyD-4ei8A:
4.9		 3eeyD-4ei8A:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fye SIDF, INHIBITOR OF
GROWTH FAMILY,
MEMBER 3

(Legionella
pneumophila) 		no annotation 3 ASN A  76
ASP A 182
GLN A  49
 None
 0.67A 3eeyD-4fyeA:
undetectable		 3eeyD-4fyeA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gbo E7

(Thermobifida
fusca) 		PF03067
(LPMO_10) 		3 ASN A  77
ASP A 120
GLN A 104
 IOD  A 311 (-3.5A)
None
None
 0.81A 3eeyD-4gboA:
undetectable		 3eeyD-4gboA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jin RIO-TYPE
SERINE/THREONINE-PRO
TEIN KINASE RIO1

(Archaeoglobus
fulgidus) 		PF01163
(RIO1) 		3 ASN A  62
ASP A 212
GLN A 215
 None
1L7  A 301 (-3.6A)
None
 0.74A 3eeyD-4jinA:
undetectable		 3eeyD-4jinA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mbo SERINE-RICH REPEAT
ADHESION
GLYCOPROTEIN (SRR1)

(Streptococcus
agalactiae) 		PF10425
(SdrG_C_C) 		3 ASN A 423
ASP A 393
GLN A 397
 None
 0.53A 3eeyD-4mboA:
undetectable		 3eeyD-4mboA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mwt LYSOSOMAL PROTECTIVE
PROTEIN

(Homo sapiens) 		PF00450
(Peptidase_S10) 		3 ASN A 305
ASP A 332
GLN A 330
 ASN  A 305 (-0.6A)
ASP  A 332 ( 0.5A)
GLN  A 330 ( 0.6A)
 0.80A 3eeyD-4mwtA:
undetectable		 3eeyD-4mwtA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nmu THIOL-DISULFIDE
OXIDOREDUCTASE RESA

(Bacillus
anthracis) 		PF00578
(AhpC-TSA) 		3 ASN A  38
ASP A  96
GLN A  99
 None
 0.84A 3eeyD-4nmuA:
undetectable		 3eeyD-4nmuA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4opu CONSERVED ARCHAEAL
PROTEIN

(Sulfolobus
acidocaldarius) 		PF01266
(DAO) 		3 ASN A 294
ASP A 183
GLN A 233
 GRG  A 503 (-4.6A)
GRG  A 502 (-3.4A)
None
 0.80A 3eeyD-4opuA:
2.9		 3eeyD-4opuA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9f HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MCBR

(Escherichia
coli) 		PF00392
(GntR)
PF07729
(FCD) 		3 ASN A 133
ASP A  19
GLN A  15
 None
 0.80A 3eeyD-4p9fA:
undetectable		 3eeyD-4p9fA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p9k TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Verminephrobacter
eiseniae) 		PF03480
(DctP) 		3 ASN A 219
ASP A 230
GLN A 231
 EAX  A 401 (-2.8A)
None
None
 0.79A 3eeyD-4p9kA:
undetectable		 3eeyD-4p9kA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pp1 HEAVY CHAIN OF FAB
FRAGMENT OF MAB 5H8

(Mus musculus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ASN D  60
ASP D  89
GLN D  86
 None
 0.74A 3eeyD-4pp1D:
undetectable		 3eeyD-4pp1D:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q66 PROTEIN BCH1

(Saccharomyces
cerevisiae) 		no annotation 3 ASN K 716
ASP K 708
GLN K 704
 None
 0.74A 3eeyD-4q66K:
undetectable		 3eeyD-4q66K:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6i T-CELL SURFACE
GLYCOPROTEIN CD4

(Homo sapiens) 		PF00047
(ig)
PF05790
(C2-set) 		3 ASN C 137
ASP C 153
GLN C 152
 None
 0.80A 3eeyD-4q6iC:
undetectable		 3eeyD-4q6iC:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yds FLAGELLA-RELATED
PROTEIN H

(Sulfolobus
acidocaldarius) 		PF06745
(ATPase) 		3 ASN A 148
ASP A 142
GLN A 138
 None
 0.76A 3eeyD-4ydsA:
3.8		 3eeyD-4ydsA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ykn PHOSPHATIDYLINOSITOL
3-KINASE REGULATORY
SUBUNIT
ALPHA,PHOSPHATIDYLIN
OSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT ALPHA
ISOFORM FUSION
PROTEIN

(Homo sapiens) 		PF00017
(SH2)
PF00454
(PI3_PI4_kinase)
PF00613
(PI3Ka)
PF00792
(PI3K_C2)
PF00794
(PI3K_rbd)
PF02192
(PI3K_p85B)
PF16454
(PI3K_P85_iSH2) 		3 ASN A1920
ASP A1810
GLN A1809
 None
 0.77A 3eeyD-4yknA:
undetectable		 3eeyD-4yknA:
9.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zel DOPAMINE
BETA-HYDROXYLASE

(Homo sapiens) 		PF01082
(Cu2_monooxygen)
PF03351
(DOMON)
PF03712
(Cu2_monoox_C) 		3 ASN A  97
ASP A 158
GLN A 128
 None
 0.83A 3eeyD-4zelA:
undetectable		 3eeyD-4zelA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a01 O-GLYCOSYLTRANSFERAS
E

(Drosophila
melanogaster) 		PF13374
(TPR_10)
PF13414
(TPR_11)
PF13844
(Glyco_transf_41) 		3 ASN A 948
ASP A 874
GLN A 876
 None
 0.68A 3eeyD-5a01A:
3.7		 3eeyD-5a01A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ao5 C-TYPE MANNOSE
RECEPTOR 2

(Homo sapiens) 		PF00040
(fn2)
PF00059
(Lectin_C) 		3 ASN A 497
ASP A 480
GLN A 450
 None
 0.80A 3eeyD-5ao5A:
undetectable		 3eeyD-5ao5A:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5awn HEAVY CHAIN OF
3BC176 FAB
LIGHT CHAIN OF
3BC176 FAB

(Homo sapiens;
Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set)
PF07654
(C1-set)
PF07686
(V-set) 		3 ASN L 128
ASP H 144
GLN H 171
 None
 0.82A 3eeyD-5awnL:
undetectable		 3eeyD-5awnL:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu1 LPG1496

(Legionella
pneumophila) 		PF12252
(SidE) 		3 ASN A 355
ASP A 351
GLN A 350
 None
 0.68A 3eeyD-5bu1A:
undetectable		 3eeyD-5bu1A:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bu2 LPG1496

(Legionella
pneumophila) 		PF12252
(SidE) 		3 ASN A 355
ASP A 351
GLN A 350
 None
 0.81A 3eeyD-5bu2A:
undetectable		 3eeyD-5bu2A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dqs ELONGATION FACTOR
1-GAMMA
ELONGATION FACTOR
1-BETA

(Homo sapiens;
Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N)
no annotation 		3 ASN A 186
ASP D  17
GLN D  13
 None
 0.81A 3eeyD-5dqsA:
undetectable		 3eeyD-5dqsA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fv4 CARBOXYLIC ESTER
HYDROLASE

(Sus scrofa) 		PF00135
(COesterase) 		3 ASN A  86
ASP A  82
GLN A  78
 None
 0.78A 3eeyD-5fv4A:
undetectable		 3eeyD-5fv4A:
17.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hbt FAB35, HEAVY CHAIN

(Rattus
norvegicus) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ASN D  60
ASP D  89
GLN D  86
 None
 0.70A 3eeyD-5hbtD:
undetectable		 3eeyD-5hbtD:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hci GPN-LOOP GTPASE 1

(Saccharomyces
cerevisiae) 		PF03029
(ATP_bind_1) 		3 ASN A 144
ASP A 200
GLN A 201
 None
 0.80A 3eeyD-5hciA:
undetectable		 3eeyD-5hciA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ho9 EXTRACELLULAR
ARABINANASE

(Geobacillus
stearothermophilus) 		PF04616
(Glyco_hydro_43)
PF16369
(GH43_C) 		3 ASN A 333
ASP A 348
GLN A 352
 None
 0.83A 3eeyD-5ho9A:
undetectable		 3eeyD-5ho9A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k3h ACYL-COENZYME A
OXIDASE

(Caenorhabditis
elegans) 		PF01756
(ACOX)
PF02770
(Acyl-CoA_dh_M)
PF14749
(Acyl-CoA_ox_N) 		3 ASN A 639
ASP A  12
GLN A   9
 None
 0.72A 3eeyD-5k3hA:
undetectable		 3eeyD-5k3hA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k9t PROTEIN TRANSLOCASE
SUBUNIT SECA

(Escherichia
coli) 		PF01043
(SecA_PP_bind)
PF07517
(SecA_DEAD) 		3 ASN A 179
ASP A 212
GLN A 570
 None
 0.78A 3eeyD-5k9tA:
2.3		 3eeyD-5k9tA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kc7 CEREBELLIN-1

(Homo sapiens) 		PF00386
(C1q) 		3 ASN A  71
ASP A  87
GLN A  88
 None
 0.82A 3eeyD-5kc7A:
undetectable		 3eeyD-5kc7A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ktk POLYKETIDE SYNTHASE
PKSJ

(Bacillus
subtilis) 		PF08659
(KR) 		3 ASN A 462
ASP A 429
GLN A 425
 None
 0.78A 3eeyD-5ktkA:
7.4		 3eeyD-5ktkA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5liq NICKING ENDONUCLEASE
N.BSPD6I

(Bacillus sp.
(in: Bacteria)) 		PF09491
(RE_AlwI) 		3 ASN A 347
ASP A 341
GLN A 337
 None
 0.79A 3eeyD-5liqA:
undetectable		 3eeyD-5liqA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mtz RIBONUCLEASE Z

(Saccharomyces
cerevisiae) 		PF13691
(Lactamase_B_4) 		3 ASN A 499
ASP A 532
GLN A 531
 None
 0.74A 3eeyD-5mtzA:
undetectable		 3eeyD-5mtzA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n4a INTRAFLAGELLAR
TRANSPORT PROTEIN 80

(Chlamydomonas
reinhardtii) 		no annotation 3 ASN A 484
ASP A 505
GLN A 522
 GOL  A 809 (-3.8A)
None
GOL  A 810 (-2.9A)
 0.72A 3eeyD-5n4aA:
undetectable		 3eeyD-5n4aA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5noi ROUNDABOUT HOMOLOG 2

(Homo sapiens) 		no annotation 3 ASN A 354
ASP A 385
GLN A 382
 None
 0.44A 3eeyD-5noiA:
undetectable		 3eeyD-5noiA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oyd CELLULASE, PUTATIVE,
CEL5D

(Cellvibrio
japonicus) 		no annotation 3 ASN A 439
ASP A 454
GLN A 456
 None
 0.73A 3eeyD-5oydA:
undetectable		 3eeyD-5oydA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5t03 MALTOSE BINDING
PROTEIN - HEPARAN
SULFATE
6-O-SULFOTRANSFERASE
ISOFORM 3 FUSION
PROTEIN

(Escherichia
coli;
Danio rerio) 		PF03567
(Sulfotransfer_2)
PF13416
(SBP_bac_8) 		3 ASN A 367
ASP A1359
GLN A1363
 EDO  A1422 (-4.3A)
None
None
 0.79A 3eeyD-5t03A:
undetectable		 3eeyD-5t03A:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vk2 PRE-GLYCOPROTEIN
POLYPROTEIN GP
COMPLEX

(Lassa
mammarenavirus) 		PF00798
(Arena_glycoprot) 		3 ASN a 302
ASP a 317
GLN a 321
 None
 0.66A 3eeyD-5vk2a:
undetectable		 3eeyD-5vk2a:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xcy GLUCANASE

(Phanerochaete
chrysosporium) 		PF01341
(Glyco_hydro_6) 		3 ASN A  85
ASP A 338
GLN A 333
 None
 0.71A 3eeyD-5xcyA:
undetectable		 3eeyD-5xcyA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yud BACULOVIRAL IAP
REPEAT-CONTAINING
PROTEIN 1E

(Mus musculus) 		no annotation 3 ASN A 828
ASP A1376
GLN A1383
 None
 0.76A 3eeyD-5yudA:
undetectable		 3eeyD-5yudA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d6v TELOMERASE REVERSE
TRANSCRIPTASE

(Tetrahymena
thermophila) 		no annotation 3 ASN A 217
ASP A 451
GLN A 440
 U  B 135 ( 3.0A)
None
None
 0.49A 3eeyD-6d6vA:
undetectable		 3eeyD-6d6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f62 SYNAPTONEMAL COMPLEX
PROTEIN 1

(Homo sapiens) 		no annotation 3 ASN A 177
ASP A 171
GLN A 167
 None
 0.82A 3eeyD-6f62A:
undetectable		 3eeyD-6f62A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6g21 PROBABLE FERULOYL
ESTERASE B-2

(Aspergillus
oryzae) 		no annotation 3 ASN A 332
ASP A 323
GLN A 319
 None
 0.74A 3eeyD-6g21A:
undetectable		 3eeyD-6g21A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6gsw MU CLASS GLUTATHIONE
S-TRANSFERASE OF
ISOENZYME 3-3

(Rattus rattus) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 ASN A  73
ASP A 161
GLN A 165
 None
 0.82A 3eeyD-6gswA:
undetectable		 3eeyD-6gswA:
21.33