SIMILAR PATTERNS OF AMINO ACIDS FOR 3EEO_A_SAMA328_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c4o DNA NUCLEOTIDE
EXCISION REPAIR
ENZYME UVRB

(Thermus
thermophilus) 		PF00271
(Helicase_C)
PF04851
(ResIII)
PF12344
(UvrB) 		3 GLU A 526
SER A 552
VAL A 551
 BOG  A9998 (-3.7A)
None
None
 0.82A 3eeoA-1c4oA:
undetectable		 3eeoA-1c4oA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eqc EXO-(B)-(1,3)-GLUCAN
ASE

(Candida
albicans) 		PF00150
(Cellulase) 		3 GLU A 179
SER A 219
VAL A 220
 None
 0.78A 3eeoA-1eqcA:
undetectable		 3eeoA-1eqcA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fuj PR3

(Homo sapiens) 		PF00089
(Trypsin) 		3 GLU A  77
SER A 117
VAL A 118
 None
 0.68A 3eeoA-1fujA:
undetectable		 3eeoA-1fujA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fy1 HEPARIN-BINDING
PROTEIN

(Homo sapiens) 		PF00089
(Trypsin) 		3 GLU A  64
SER A 104
VAL A 105
 None
EOH  A 300 ( 4.8A)
None
 0.68A 3eeoA-1fy1A:
undetectable		 3eeoA-1fy1A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4u NIDOGEN-1

(Mus musculus) 		PF07474
(G2F) 		3 GLU A 485
SER A 368
VAL A 369
 None
 0.79A 3eeoA-1h4uA:
undetectable		 3eeoA-1h4uA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h76 SEROTRANSFERRIN

(Sus scrofa) 		PF00405
(Transferrin) 		3 GLU A 355
SER A 394
VAL A 596
 None
 0.83A 3eeoA-1h76A:
undetectable		 3eeoA-1h76A:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hng CD2

(Rattus rattus) 		PF05790
(C2-set)
PF07686
(V-set) 		3 GLU A 168
SER A 102
VAL A 101
 None
 0.78A 3eeoA-1hngA:
undetectable		 3eeoA-1hngA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1idm 3-ISOPROPYLMALATE
DEHYDROGENASE

(Thermus
thermophilus) 		PF00180
(Iso_dh) 		3 GLU A 198
SER A 180
VAL A 232
 None
 0.65A 3eeoA-1idmA:
2.1		 3eeoA-1idmA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kho ALPHA-TOXIN

(Clostridium
perfringens) 		PF00882
(Zn_dep_PLPC)
PF01477
(PLAT) 		3 GLU A  30
SER A 244
VAL A 243
 None
 0.81A 3eeoA-1khoA:
undetectable		 3eeoA-1khoA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1mwo ALPHA AMYLASE

(Pyrococcus
woesei) 		PF00128
(Alpha-amylase)
PF09154
(DUF1939) 		3 GLU A 181
SER A 136
VAL A 134
 None
 0.83A 3eeoA-1mwoA:
undetectable		 3eeoA-1mwoA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ogo DEXTRANASE

(Talaromyces
minioluteus) 		PF03718
(Glyco_hydro_49)
PF17433
(Glyco_hydro_49N) 		3 GLU X 485
SER X 161
VAL X 195
 None
 0.79A 3eeoA-1ogoX:
undetectable		 3eeoA-1ogoX:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q1l CHORISMATE SYNTHASE

(Aquifex
aeolicus) 		PF01264
(Chorismate_synt) 		3 GLU A  40
SER A 162
VAL A 230
 None
 0.79A 3eeoA-1q1lA:
undetectable		 3eeoA-1q1lA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1q6w MONOAMINE OXIDASE
REGULATORY PROTEIN,
PUTATIVE

(Archaeoglobus
fulgidus) 		PF01575
(MaoC_dehydratas) 		3 GLU A  16
SER A  91
VAL A  92
 None
 0.81A 3eeoA-1q6wA:
undetectable		 3eeoA-1q6wA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tki TITIN

(Homo sapiens) 		PF00069
(Pkinase) 		3 GLU A 164
SER A 317
VAL A  38
 None
 0.83A 3eeoA-1tkiA:
undetectable		 3eeoA-1tkiA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ua4 ADP-DEPENDENT
GLUCOKINASE

(Pyrococcus
furiosus) 		PF04587
(ADP_PFK_GK) 		3 GLU A 352
SER A 288
VAL A 289
 None
 0.82A 3eeoA-1ua4A:
3.0		 3eeoA-1ua4A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ur4 GALACTANASE

(Bacillus
licheniformis) 		PF07745
(Glyco_hydro_53) 		3 GLU A  46
SER A 384
VAL A 293
 None
 0.81A 3eeoA-1ur4A:
undetectable		 3eeoA-1ur4A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v3t LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE/PROSTAGLANDIN
15-KETO REDUCTASE

(Cavia porcellus) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		3 GLU A 300
SER A  45
VAL A  46
 None
 0.80A 3eeoA-1v3tA:
5.5		 3eeoA-1v3tA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vct HYPOTHETICAL PROTEIN
PH0236

(Pyrococcus
horikoshii) 		PF01895
(PhoU)
PF02080
(TrkA_C) 		3 GLU A 191
SER A 132
VAL A 133
 None
 0.71A 3eeoA-1vctA:
undetectable		 3eeoA-1vctA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz1 IG HEAVY CHAIN

(Mus musculus) 		PF07686
(V-set) 		3 GLU H  42
SER H  65
VAL H  66
 None
 0.84A 3eeoA-1wz1H:
undetectable		 3eeoA-1wz1H:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wz2 LEUCYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		3 GLU A 442
SER A 266
VAL A 265
 None
 0.82A 3eeoA-1wz2A:
undetectable		 3eeoA-1wz2A:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y13 6-PYRUVOYL
TETRAHYDROPTERIN
SYNTHASE

(Plasmodium
falciparum) 		PF01242
(PTPS) 		3 GLU A 129
SER A  88
VAL A  90
 None
 0.83A 3eeoA-1y13A:
undetectable		 3eeoA-1y13A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yqe HYPOTHETICAL UPF0204
PROTEIN AF0625

(Archaeoglobus
fulgidus) 		PF04414
(tRNA_deacylase) 		3 GLU A 143
SER A  90
VAL A  89
 None
 0.82A 3eeoA-1yqeA:
undetectable		 3eeoA-1yqeA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2bi3 PHOSPHOSERINE
AMINOTRANSFERASE

(Bacillus
alcalophilus) 		PF00266
(Aminotran_5) 		3 GLU A 104
SER A 329
VAL A 330
 PEG  A1368 (-3.5A)
None
None
 0.79A 3eeoA-2bi3A:
undetectable		 3eeoA-2bi3A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cw7 ENDONUCLEASE
PI-PKOII

(Thermococcus
kodakarensis) 		PF14528
(LAGLIDADG_3)
PF14890
(Intein_splicing) 		3 GLU A 113
SER A 100
VAL A 120
 None
 0.81A 3eeoA-2cw7A:
undetectable		 3eeoA-2cw7A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d7v HYPOTHETICAL PROTEIN
VCA0330

(Vibrio cholerae) 		PF02566
(OsmC) 		3 GLU A  67
SER A  58
VAL A  55
 None
 0.81A 3eeoA-2d7vA:
undetectable		 3eeoA-2d7vA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g39 ACETYL-COA HYDROLASE

(Pseudomonas
aeruginosa) 		PF02550
(AcetylCoA_hydro)
PF13336
(AcetylCoA_hyd_C) 		3 GLU A 288
SER A  67
VAL A  90
 ACY  A 901 (-2.6A)
None
None
 0.85A 3eeoA-2g39A:
undetectable		 3eeoA-2g39A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		3 GLU A 379
SER A 409
VAL A 411
 None
 0.75A 3eeoA-2gmhA:
2.9		 3eeoA-2gmhA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h21 RIBULOSE-1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E

(Pisum sativum) 		PF00856
(SET)
PF09273
(Rubis-subs-bind) 		3 GLU A 114
SER A 141
VAL A 142
 None
 0.58A 3eeoA-2h21A:
undetectable		 3eeoA-2h21A:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h2w HOMOSERINE
O-SUCCINYLTRANSFERAS
E

(Thermotoga
maritima) 		PF04204
(HTS) 		3 GLU A 208
SER A 176
VAL A 177
 None
 0.79A 3eeoA-2h2wA:
4.1		 3eeoA-2h2wA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hau SEROTRANSFERRIN

(Homo sapiens) 		PF00405
(Transferrin) 		3 GLU A 351
SER A 390
VAL A 587
 None
 0.80A 3eeoA-2hauA:
undetectable		 3eeoA-2hauA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hnh DNA POLYMERASE III
ALPHA SUBUNIT

(Escherichia
coli) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		3 GLU A 389
SER A 368
VAL A 370
 None
 0.76A 3eeoA-2hnhA:
undetectable		 3eeoA-2hnhA:
16.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2i9k MODIFICATION
METHYLASE HHAI

(Haemophilus
haemolyticus) 		PF00145
(DNA_methylase) 		3 GLU A  40
SER A 305
VAL A 306
 SAH  A 328 (-2.8A)
SAH  A 328 (-2.7A)
SAH  A 328 (-4.4A)
 0.46A 3eeoA-2i9kA:
54.1		 3eeoA-2i9kA:
99.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iya OLEANDOMYCIN
GLYCOSYLTRANSFERASE

(Streptomyces
antibioticus) 		PF00201
(UDPGT) 		3 GLU A 352
SER A 137
VAL A 215
 ZIO  A1425 (-3.8A)
None
None
 0.84A 3eeoA-2iyaA:
5.3		 3eeoA-2iyaA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2okx RHAMNOSIDASE B

(Bacillus sp.
GL1) 		PF05592
(Bac_rhamnosid)
PF08531
(Bac_rhamnosid_N)
PF17389
(Bac_rhamnosid6H)
PF17390
(Bac_rhamnosid_C) 		3 GLU A 692
SER A 759
VAL A 761
 None
 0.78A 3eeoA-2okxA:
undetectable		 3eeoA-2okxA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2q48 PROTEIN AT5G48480

(Arabidopsis
thaliana) 		no annotation 3 GLU A  33
SER A 101
VAL A 103
 None
 0.77A 3eeoA-2q48A:
undetectable		 3eeoA-2q48A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v1u CELL DIVISION
CONTROL PROTEIN 6
HOMOLOG

(Aeropyrum
pernix) 		PF09079
(Cdc6_C)
PF13191
(AAA_16) 		3 GLU A 325
SER A 310
VAL A 307
 None
 0.84A 3eeoA-2v1uA:
undetectable		 3eeoA-2v1uA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xwb COMPLEMENT C3B
ALPHA' CHAIN

(Homo sapiens) 		PF00207
(A2M)
PF01759
(NTR)
PF07677
(A2M_recep)
PF07678
(A2M_comp)
PF10569
(Thiol-ester_cl) 		3 GLU B1411
SER B 873
VAL B 828
 None
 0.63A 3eeoA-2xwbB:
undetectable		 3eeoA-2xwbB:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zb3 PROSTAGLANDIN
REDUCTASE 2

(Mus musculus) 		PF00107
(ADH_zinc_N)
PF16884
(ADH_N_2) 		3 GLU A 316
SER A  47
VAL A  48
 None
 0.76A 3eeoA-2zb3A:
undetectable		 3eeoA-2zb3A:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zzg ALANYL-TRNA
SYNTHETASE

(Pyrococcus
horikoshii) 		PF01411
(tRNA-synt_2c)
PF07973
(tRNA_SAD) 		3 GLU A 744
SER A 359
VAL A 361
 None
 0.81A 3eeoA-2zzgA:
undetectable		 3eeoA-2zzgA:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c5n TUBBY-RELATED
PROTEIN 1

(Homo sapiens) 		PF01167
(Tub) 		3 GLU A 458
SER A 434
VAL A 435
 I3P  A   2 ( 4.7A)
I3P  A   2 (-2.5A)
I3P  A   2 ( 3.4A)
 0.62A 3eeoA-3c5nA:
undetectable		 3eeoA-3c5nA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d4o DIPICOLINATE
SYNTHASE SUBUNIT A

(Bacillus
halodurans) 		PF01262
(AlaDh_PNT_C)
PF16924
(DpaA_N) 		3 GLU A  52
SER A  31
VAL A   8
 None
 0.76A 3eeoA-3d4oA:
6.2		 3eeoA-3d4oA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3e38 TWO-DOMAIN PROTEIN
CONTAINING PREDICTED
PHP-LIKE
METAL-DEPENDENT
PHOSPHOESTERASE

(Bacteroides
vulgatus) 		PF16392
(DUF5001) 		3 GLU A  62
SER A  47
VAL A  48
 None
 0.64A 3eeoA-3e38A:
undetectable		 3eeoA-3e38A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3eu8 PUTATIVE
GLUCOAMYLASE

(Bacteroides
fragilis) 		PF10091
(Glycoamylase)
PF11329
(DUF3131) 		3 GLU A 177
SER A 105
VAL A 104
 EDO  A 458 ( 4.1A)
None
None
 0.69A 3eeoA-3eu8A:
undetectable		 3eeoA-3eu8A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f2b DNA-DIRECTED DNA
POLYMERASE III ALPHA
CHAIN

(Geobacillus
kaustophilus) 		PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		3 GLU A 961
SER A 899
VAL A 901
 None
 0.83A 3eeoA-3f2bA:
undetectable		 3eeoA-3f2bA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxa SIS DOMAIN PROTEIN

(Listeria
monocytogenes) 		PF01380
(SIS) 		3 GLU A 147
SER A 143
VAL A  27
 None
 0.83A 3eeoA-3fxaA:
3.6		 3eeoA-3fxaA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h20 REPLICATION PROTEIN
B

(Plasmid RSF1010) 		PF16793
(RepB_primase) 		3 GLU A 223
SER A 252
VAL A 296
 None
 0.78A 3eeoA-3h20A:
undetectable		 3eeoA-3h20A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k2w BETAINE-ALDEHYDE
DEHYDROGENASE

(Pseudoalteromonas
atlantica) 		PF00171
(Aldedh) 		3 GLU A 336
SER A 234
VAL A 236
 None
 0.80A 3eeoA-3k2wA:
undetectable		 3eeoA-3k2wA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ka7 OXIDOREDUCTASE

(Methanosarcina
mazei) 		PF01593
(Amino_oxidase) 		3 GLU A 169
SER A 279
VAL A 376
 None
None
FAD  A 500 (-3.2A)
 0.75A 3eeoA-3ka7A:
2.8		 3eeoA-3ka7A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lb6 INTERLEUKIN-13
RECEPTOR SUBUNIT
ALPHA-2

(Homo sapiens) 		PF09240
(IL6Ra-bind) 		3 GLU D  70
SER D 121
VAL D  32
 None
 0.76A 3eeoA-3lb6D:
undetectable		 3eeoA-3lb6D:
22.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3lx6 CYTOSINE-SPECIFIC
METHYLTRANSFERASE

(Shigella
flexneri) 		PF00145
(DNA_methylase) 		3 GLU A 115
SER A 437
VAL A 438
 None
 0.74A 3eeoA-3lx6A:
29.3		 3eeoA-3lx6A:
33.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3me5 CYTOSINE-SPECIFIC
METHYLTRANSFERASE

(Shigella
flexneri) 		PF00145
(DNA_methylase) 		3 GLU A 115
SER A 437
VAL A 438
 None
 0.33A 3eeoA-3me5A:
26.8		 3eeoA-3me5A:
30.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mt1 PUTATIVE
CARBOXYNORSPERMIDINE
DECARBOXYLASE
PROTEIN

(Sinorhizobium
meliloti) 		PF00278
(Orn_DAP_Arg_deC) 		3 GLU A  62
SER A  78
VAL A  79
 None
 0.76A 3eeoA-3mt1A:
undetectable		 3eeoA-3mt1A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3naf CALCIUM-ACTIVATED
POTASSIUM CHANNEL
SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1,CALCIUM-ACTI
VATED POTASSIUM
CHANNEL SUBUNIT
ALPHA-1

(Homo sapiens) 		PF03493
(BK_channel_a) 		3 GLU A 709
SER A 777
VAL A 755
 None
 0.83A 3eeoA-3nafA:
3.7		 3eeoA-3nafA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3npf PUTATIVE
DIPEPTIDYL-PEPTIDASE
VI

(Bacteroides
ovatus) 		PF00877
(NLPC_P60) 		3 GLU A 121
SER A 162
VAL A 108
 None
 0.72A 3eeoA-3npfA:
undetectable		 3eeoA-3npfA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3or2 SULFITE REDCUTASE
SUBUNIT BETA

(Desulfovibrio
gigas) 		PF00037
(Fer4)
PF01077
(NIR_SIR)
PF03460
(NIR_SIR_ferr) 		3 GLU B 220
SER B 250
VAL B 251
 None
 0.76A 3eeoA-3or2B:
undetectable		 3eeoA-3or2B:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qsg NAD-BINDING
PHOSPHOGLUCONATE
DEHYDROGENASE-LIKE
PROTEIN

(Alicyclobacillus
acidocaldarius) 		PF03807
(F420_oxidored)
PF09130
(DUF1932) 		3 GLU A  55
SER A  48
VAL A  47
 None
 0.78A 3eeoA-3qsgA:
3.3		 3eeoA-3qsgA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rjd HIGH AFFINITY
IMMUNOGLOBULIN GAMMA
FC RECEPTOR I

(Homo sapiens) 		PF00047
(ig)
PF13895
(Ig_2)
PF13927
(Ig_3) 		3 GLU A 118
SER A 110
VAL A 109
 None
 0.56A 3eeoA-3rjdA:
undetectable		 3eeoA-3rjdA:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s5r TRANSCRIPTIONAL
REGULATOR TETR
FAMILY

(Syntrophus
aciditrophicus) 		PF00440
(TetR_N) 		3 GLU A  24
SER A  38
VAL A  39
 None
 0.65A 3eeoA-3s5rA:
undetectable		 3eeoA-3s5rA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3skp SEROTRANSFERRIN

(Homo sapiens) 		PF00405
(Transferrin) 		3 GLU A 351
SER A 390
VAL A 587
 None
 0.83A 3eeoA-3skpA:
undetectable		 3eeoA-3skpA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t1i DOUBLE-STRAND BREAK
REPAIR PROTEIN
MRE11A

(Homo sapiens) 		PF00149
(Metallophos)
PF04152
(Mre11_DNA_bind) 		3 GLU A  42
SER A 269
VAL A 270
 None
 0.84A 3eeoA-3t1iA:
undetectable		 3eeoA-3t1iA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u95 GLYCOSIDE HYDROLASE,
FAMILY 4

(Thermotoga
neapolitana) 		PF02056
(Glyco_hydro_4)
PF11975
(Glyco_hydro_4C) 		3 GLU A  30
SER A  60
VAL A  55
 None
 0.67A 3eeoA-3u95A:
4.6		 3eeoA-3u95A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uar GLUTATHIONE
S-TRANSFERASE

(Methylococcus
capsulatus) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 GLU A  90
SER A 153
VAL A 154
 None
 0.75A 3eeoA-3uarA:
undetectable		 3eeoA-3uarA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uyq CARBONIC ANHYDRASE 3

(Homo sapiens) 		PF00194
(Carb_anhydrase) 		3 GLU A   4
SER A 230
VAL A 238
 None
 0.77A 3eeoA-3uyqA:
undetectable		 3eeoA-3uyqA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wd8 TYPE III POLYKETIDE
SYNTHASE QUINOLONE
SYNTHASE

(Citrus x
microcarpa) 		PF00195
(Chal_sti_synt_N)
PF02797
(Chal_sti_synt_C) 		3 GLU A 179
SER A 242
VAL A 382
 None
 0.75A 3eeoA-3wd8A:
undetectable		 3eeoA-3wd8A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zyv AOX3

(Mus musculus) 		PF00111
(Fer2)
PF00941
(FAD_binding_5)
PF01315
(Ald_Xan_dh_C)
PF01799
(Fer2_2)
PF02738
(Ald_Xan_dh_C2)
PF03450
(CO_deh_flav_C) 		3 GLU A1242
SER A1165
VAL A1275
 None
 0.85A 3eeoA-3zyvA:
undetectable		 3eeoA-3zyvA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4chb KELCH-LIKE PROTEIN 2

(Homo sapiens) 		PF01344
(Kelch_1) 		3 GLU A 324
SER A 575
VAL A 573
 None
 0.80A 3eeoA-4chbA:
undetectable		 3eeoA-4chbA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4dg8 PA1221

(Pseudomonas
aeruginosa) 		PF00501
(AMP-binding) 		3 GLU A  69
SER A 153
VAL A 154
 None
 0.82A 3eeoA-4dg8A:
2.3		 3eeoA-4dg8A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hvt POST-PROLINE
CLEAVING ENZYME

(Rickettsia
typhi) 		PF00326
(Peptidase_S9)
PF02897
(Peptidase_S9_N) 		3 GLU A 690
SER A 646
VAL A 647
 None
 0.76A 3eeoA-4hvtA:
2.7		 3eeoA-4hvtA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ij2 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H

(Staphylococcus
aureus) 		PF05031
(NEAT) 		3 GLU E 559
SER E 563
VAL E 564
 None
 0.78A 3eeoA-4ij2E:
undetectable		 3eeoA-4ij2E:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jso OLIGOPEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
OLIGOPEPTIDE-BINDING
PROTEIN

(Thermotoga
maritima) 		PF00496
(SBP_bac_5) 		3 GLU A 461
SER A 427
VAL A 428
 None
 0.80A 3eeoA-4jsoA:
undetectable		 3eeoA-4jsoA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kw7 ARSENIC
METHYLTRANSFERASE

(Cyanidioschyzon
sp. 5508) 		PF13847
(Methyltransf_31) 		3 GLU A 160
SER A 166
VAL A 167
 None
 0.78A 3eeoA-4kw7A:
7.3		 3eeoA-4kw7A:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nge PRESEQUENCE
PROTEASE,
MITOCHONDRIAL

(Homo sapiens) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		3 GLU D 709
SER D 620
VAL D 621
 None
 0.73A 3eeoA-4ngeD:
undetectable		 3eeoA-4ngeD:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4o3s DNA POLYMERASE ETA

(Homo sapiens) 		PF00817
(IMS)
PF11799
(IMS_C) 		3 GLU A 306
SER A 217
VAL A 238
 None
 0.82A 3eeoA-4o3sA:
undetectable		 3eeoA-4o3sA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ope NRPS/PKS

(Streptomyces
albus) 		PF00109
(ketoacyl-synt)
PF02801
(Ketoacyl-synt_C)
PF16197
(KAsynt_C_assoc) 		3 GLU A4225
SER A4653
VAL A4654
 None
 0.78A 3eeoA-4opeA:
undetectable		 3eeoA-4opeA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qmk TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN EXOU

(Pseudomonas
fluorescens) 		PF01734
(Patatin) 		3 GLU A 319
SER A  50
VAL A  49
 None
 0.76A 3eeoA-4qmkA:
undetectable		 3eeoA-4qmkA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u1f EUKARYOTIC
TRANSLATION
INITIATION FACTOR 3
SUBUNIT B

(Saccharomyces
cerevisiae) 		PF08662
(eIF2A) 		3 GLU A 456
SER A 557
VAL A 556
 None
 0.81A 3eeoA-4u1fA:
undetectable		 3eeoA-4u1fA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uer EIF3B

(Lachancea
kluyveri) 		PF00318
(Ribosomal_S2) 		3 GLU b 522
SER b 623
VAL b 622
 None
 0.80A 3eeoA-4uerb:
undetectable		 3eeoA-4uerb:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wqm TOLUENE-4-MONOOXYGEN
ASE ELECTRON
TRANSFER COMPONENT

(Pseudomonas
mendocina) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		3 GLU A 116
SER A 263
VAL A 264
 None
 0.84A 3eeoA-4wqmA:
2.6		 3eeoA-4wqmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wqm TOLUENE-4-MONOOXYGEN
ASE ELECTRON
TRANSFER COMPONENT

(Pseudomonas
mendocina) 		PF00111
(Fer2)
PF00175
(NAD_binding_1)
PF00970
(FAD_binding_6) 		3 GLU A 241
SER A 263
VAL A 264
 None
 0.81A 3eeoA-4wqmA:
2.6		 3eeoA-4wqmA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xii CHOLINESTERASE

(Homo sapiens) 		PF00135
(COesterase) 		3 GLU A 367
SER A 362
VAL A 361
 None
 0.77A 3eeoA-4xiiA:
2.5		 3eeoA-4xiiA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xmv AMINOPEPTIDASE N

(Escherichia
coli) 		PF01433
(Peptidase_M1)
PF11940
(DUF3458)
PF17432
(DUF3458_C) 		3 GLU A 398
SER A 429
VAL A 431
 None
 0.84A 3eeoA-4xmvA:
undetectable		 3eeoA-4xmvA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4y0b DOUBLE CLP-N MOTIF
PROTEIN

(Arabidopsis
thaliana) 		PF02861
(Clp_N) 		3 GLU A 222
SER A 181
VAL A 183
 None
 0.81A 3eeoA-4y0bA:
undetectable		 3eeoA-4y0bA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c3u L-SERINE
AMMONIA-LYASE

(Rhizomucor
miehei) 		PF00291
(PALP) 		3 GLU A 246
SER A 241
VAL A 240
 None
 0.84A 3eeoA-5c3uA:
2.1		 3eeoA-5c3uA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5c91 E3 UBIQUITIN-PROTEIN
LIGASE NEDD4

(Homo sapiens) 		PF00632
(HECT) 		3 GLU A 774
SER A 676
VAL A 677
 None
 0.79A 3eeoA-5c91A:
undetectable		 3eeoA-5c91A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cvi SLOR

(Streptococcus
mutans) 		PF01325
(Fe_dep_repress)
PF02742
(Fe_dep_repr_C)
PF04023
(FeoA) 		3 GLU A 111
SER A 106
VAL A 105
 ZN  A 304 (-3.2A)
None
None
 0.82A 3eeoA-5cviA:
undetectable		 3eeoA-5cviA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5dt9 ERYTHRONATE-4-PHOSPH
ATE DEHYDROGENASE

(Vibrio cholerae) 		PF00389
(2-Hacid_dh)
PF02826
(2-Hacid_dh_C)
PF11890
(DUF3410) 		3 GLU A 314
SER A 120
VAL A 121
 None
 0.76A 3eeoA-5dt9A:
3.4		 3eeoA-5dt9A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e5b FACT COMPLEX SUBUNIT
SPT16

(Homo sapiens) 		PF00557
(Peptidase_M24)
PF14826
(FACT-Spt16_Nlob) 		3 GLU A 204
SER A 220
VAL A 221
 None
 0.81A 3eeoA-5e5bA:
undetectable		 3eeoA-5e5bA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fku DNA POLYMERASE III
SUBUNIT ALPHA

(Escherichia
coli) 		PF01336
(tRNA_anti-codon)
PF02811
(PHP)
PF07733
(DNA_pol3_alpha)
PF14579
(HHH_6) 		3 GLU A 389
SER A 368
VAL A 370
 None
 0.76A 3eeoA-5fkuA:
undetectable		 3eeoA-5fkuA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fmg PROTEOSOME SUBUNIT
ALPHA TYPE 1,
PUTATIVE

(Plasmodium
falciparum) 		PF00227
(Proteasome)
PF10584
(Proteasome_A_N) 		3 GLU F 172
SER F 159
VAL F  36
 None
 0.78A 3eeoA-5fmgF:
undetectable		 3eeoA-5fmgF:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsa CYP51 VARIANT1

(Candida
albicans) 		PF00067
(p450) 		3 GLU A 102
SER A 453
VAL A 452
 None
 0.61A 3eeoA-5fsaA:
undetectable		 3eeoA-5fsaA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hh9 PVDN

(Pseudomonas
aeruginosa) 		PF00266
(Aminotran_5) 		3 GLU A 215
SER A 179
VAL A 178
 None
 0.82A 3eeoA-5hh9A:
2.9		 3eeoA-5hh9A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1

(Saccharomyces
cerevisiae) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 GLU A1139
SER A1145
VAL A1146
 None
 0.73A 3eeoA-5ip9A:
undetectable		 3eeoA-5ip9A:
11.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jwz CELLULOSE-BINDING
FAMILY II

(Streptomyces
sp. SirexAA-E) 		PF02012
(BNR) 		3 GLU A 567
SER A 538
VAL A 544
 CA  A 803 ( 4.4A)
None
None
 0.84A 3eeoA-5jwzA:
undetectable		 3eeoA-5jwzA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k39 CELLULOSOME
ANCHORING PROTEIN
COHESIN REGION

(Ruminiclostridium
thermocellum) 		PF00963
(Cohesin) 		3 GLU A  74
SER A 105
VAL A 107
 None
 0.79A 3eeoA-5k39A:
undetectable		 3eeoA-5k39A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5khl HEMIN ABC
TRANSPORTER,
PERIPLASMIC
HEMIN-BINDING
PROTEIN HUTB

(Vibrio cholerae) 		PF01497
(Peripla_BP_2) 		3 GLU B 165
SER B 217
VAL B 216
 None
 0.81A 3eeoA-5khlB:
2.4		 3eeoA-5khlB:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kx6 GALACTOSIDE
2-ALPHA-L-FUCOSYLTRA
NSFERASE

(Arabidopsis
thaliana) 		PF03254
(XG_FTase) 		3 GLU A 424
SER A 417
VAL A 365
 None
 0.84A 3eeoA-5kx6A:
undetectable		 3eeoA-5kx6A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tw1 DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA

(Mycolicibacterium
smegmatis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF10385
(RNA_pol_Rpb2_45) 		3 GLU C 420
SER C 428
VAL C 166
 None
 0.73A 3eeoA-5tw1C:
undetectable		 3eeoA-5tw1C:
14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u03 CTP SYNTHASE 1

(Homo sapiens) 		PF00117
(GATase)
PF06418
(CTP_synth_N) 		3 GLU A 322
SER A 248
VAL A 247
 None
None
ATP  A 601 (-3.9A)
 0.82A 3eeoA-5u03A:
2.9		 3eeoA-5u03A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6egt GLYCOPROTEIN

(Rift Valley
fever
phlebovirus) 		no annotation 3 GLU A 782
SER A 774
VAL A1133
 None
 0.80A 3eeoA-6egtA:
undetectable		 3eeoA-6egtA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fpc PRO-PRO
ENDOPEPTIDASE

(Paenibacillus
alvei) 		no annotation 3 GLU A 181
SER A 112
VAL A 116
 ZN  A 301 ( 2.1A)
None
None
 0.82A 3eeoA-6fpcA:
undetectable		 3eeoA-6fpcA:
undetectable