SIMILAR PATTERNS OF AMINO ACIDS FOR 3E7I_B_H4BB2902_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1a80 2,5-DIKETO-D-GLUCONI
C ACID REDUCTASE A

(Corynebacterium
sp.) 		PF00248
(Aldo_ket_red) 		3 ARG A 171
ILE A 255
TRP A 221
 None
 1.02A 3e7iB-1a80A:
0.0		 3e7iB-1a80A:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g5b SERINE/THREONINE
PROTEIN PHOSPHATASE

(Escherichia
virus Lambda) 		PF00149
(Metallophos) 		3 ARG A 162
ILE A 159
TRP A 160
 SO4  A3001 (-3.3A)
None
None
 0.91A 3e7iB-1g5bA:
undetectable		 3e7iB-1g5bA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gnx BETA-GLUCOSIDASE

(Streptomyces
sp.) 		PF00232
(Glyco_hydro_1) 		3 ARG A  56
ILE A  46
TRP A  47
 None
 1.10A 3e7iB-1gnxA:
0.0		 3e7iB-1gnxA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hpl LIPASE

(Equus caballus) 		PF00151
(Lipase)
PF01477
(PLAT) 		3 ARG A 439
ILE A 401
TRP A 402
 None
 1.13A 3e7iB-1hplA:
0.0		 3e7iB-1hplA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iir GLYCOSYLTRANSFERASE
GTFB

(Amycolatopsis
orientalis) 		PF03033
(Glyco_transf_28) 		3 ARG A 157
ILE A 151
TRP A 155
 None
 1.07A 3e7iB-1iirA:
0.1		 3e7iB-1iirA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1iiw SLR1257 PROTEIN

(Synechocystis
sp. PCC 6803) 		PF00497
(SBP_bac_3) 		3 ARG A  36
ILE A  30
TRP A 224
 None
 1.05A 3e7iB-1iiwA:
0.0		 3e7iB-1iiwA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jqg CARBOXYPEPTIDASE A

(Helicoverpa
armigera) 		PF00246
(Peptidase_M14)
PF02244
(Propep_M14) 		3 ARG A 302
ILE A 100
TRP A 105
 None
 1.06A 3e7iB-1jqgA:
0.0		 3e7iB-1jqgA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1kb0 QUINOHEMOPROTEIN
ALCOHOL
DEHYDROGENASE

(Comamonas
testosteroni) 		PF13360
(PQQ_2)
PF13442
(Cytochrome_CBB3) 		3 ARG A  67
ILE A 107
TRP A 136
 HEC  A 802 (-4.2A)
None
None
 1.13A 3e7iB-1kb0A:
undetectable		 3e7iB-1kb0A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1p22 F-BOX/WD-REPEAT
PROTEIN 1A

(Homo sapiens) 		PF00400
(WD40)
PF12937
(F-box-like) 		3 ARG A 384
ILE A 403
TRP A 415
 None
 1.08A 3e7iB-1p22A:
0.0		 3e7iB-1p22A:
21.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1qw5 NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Mus musculus) 		PF02898
(NO_synthase) 		3 ARG A 375
ILE A 456
TRP A 457
 H4B  A 901 (-3.4A)
H4B  A 901 (-4.7A)
H4B  A 901 ( 3.7A)
 0.48A 3e7iB-1qw5A:
60.6		 3e7iB-1qw5A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rk2 RIBOKINASE

(Escherichia
coli) 		PF00294
(PfkB) 		3 ARG A 227
ILE A 222
TRP A 230
 None
 1.16A 3e7iB-1rk2A:
undetectable		 3e7iB-1rk2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tmo TRIMETHYLAMINE
N-OXIDE REDUCTASE

(Shewanella
massilia) 		PF00384
(Molybdopterin)
PF01568
(Molydop_binding) 		3 ARG A 410
ILE A 415
TRP A 411
 None
 1.12A 3e7iB-1tmoA:
undetectable		 3e7iB-1tmoA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v10 LACCASE

(Rigidoporus
microporus) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 121
ILE A 454
TRP A 456
 None
CU  A1503 (-3.4A)
None
 0.98A 3e7iB-1v10A:
undetectable		 3e7iB-1v10A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v26 LONG-CHAIN-FATTY-ACI
D-COA SYNTHETASE

(Thermus
thermophilus) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		3 ARG A 199
ILE A 393
TRP A 392
 None
 0.94A 3e7iB-1v26A:
undetectable		 3e7iB-1v26A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w36 EXODEOXYRIBONUCLEASE
V GAMMA CHAIN

(Escherichia
coli) 		PF04257
(Exonuc_V_gamma) 		3 ARG C 582
ILE C 573
TRP C 574
 None
 0.99A 3e7iB-1w36C:
undetectable		 3e7iB-1w36C:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wlt 176AA LONG
HYPOTHETICAL
DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE

(Sulfurisphaera
tokodaii) 		PF00908
(dTDP_sugar_isom) 		3 ARG A  40
ILE A  13
TRP A 111
 None
 0.95A 3e7iB-1wltA:
undetectable		 3e7iB-1wltA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wms RAS-RELATED PROTEIN
RAB-9A

(Homo sapiens) 		PF00071
(Ras) 		3 ARG A  78
ILE A  11
TRP A  61
 None
 1.08A 3e7iB-1wmsA:
undetectable		 3e7iB-1wmsA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xeu INTERNALIN C

(Listeria
monocytogenes) 		PF08191
(LRR_adjacent)
PF12354
(Internalin_N)
PF12799
(LRR_4) 		3 ARG A 170
ILE A 211
TRP A 210
 None
 1.15A 3e7iB-1xeuA:
undetectable		 3e7iB-1xeuA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xio ANABAENA SENSORY
RHODOPSIN

(Nostoc sp. PCC
7120) 		PF01036
(Bac_rhodopsin) 		3 ARG A 155
ILE A 146
TRP A 147
 None
None
PEE  A 306 ( 3.6A)
 1.12A 3e7iB-1xioA:
undetectable		 3e7iB-1xioA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1y79 PEPTIDYL-DIPEPTIDASE
DCP

(Escherichia
coli) 		PF01432
(Peptidase_M3) 		3 ARG 1 248
ILE 1 243
TRP 1 246
 None
 1.10A 3e7iB-1y791:
undetectable		 3e7iB-1y791:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z06 RAS-RELATED PROTEIN
RAB-33B

(Mus musculus) 		PF00071
(Ras) 		3 ARG A 105
ILE A  37
TRP A  87
 None
 1.11A 3e7iB-1z06A:
undetectable		 3e7iB-1z06A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1z1w TRICORN PROTEASE
INTERACTING FACTOR
F3

(Thermoplasma
acidophilum) 		PF01433
(Peptidase_M1)
PF11838
(ERAP1_C) 		3 ARG A 178
ILE A 212
TRP A 271
 None
 0.91A 3e7iB-1z1wA:
undetectable		 3e7iB-1z1wA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2a46 GFP-LIKE FLUORESCENT
CHROMOPROTEIN
AMFP486

(Anemonia majano) 		PF01353
(GFP) 		3 ARG A  72
ILE A 113
TRP A 111
 CR7  A  68 ( 4.4A)
None
CR7  A  68 ( 4.1A)
 0.92A 3e7iB-2a46A:
undetectable		 3e7iB-2a46A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ayu NUCLEOSOME ASSEMBLY
PROTEIN

(Saccharomyces
cerevisiae) 		PF00956
(NAP) 		3 ARG A 355
ILE A 131
TRP A 132
 None
 0.86A 3e7iB-2ayuA:
undetectable		 3e7iB-2ayuA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fkn UROCANATE HYDRATASE

(Bacillus
subtilis) 		PF01175
(Urocanase)
PF17391
(Urocanase_N)
PF17392
(Urocanase_C) 		3 ARG A 414
ILE A 406
TRP A 408
 None
 0.87A 3e7iB-2fknA:
undetectable		 3e7iB-2fknA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jaq DEOXYGUANOSINE
KINASE

(Mycoplasma
mycoides) 		PF01712
(dNK) 		3 ARG A 145
ILE A 139
TRP A 158
 DCP  A1202 (-2.8A)
None
None
 0.97A 3e7iB-2jaqA:
undetectable		 3e7iB-2jaqA:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ljr GLUTATHIONE
S-TRANSFERASE

(Homo sapiens) 		PF00043
(GST_C)
PF02798
(GST_N) 		3 ARG A 107
ILE A 112
TRP A 115
 None
 1.03A 3e7iB-2ljrA:
undetectable		 3e7iB-2ljrA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nba PREPILIN-TYPE
CLEAVAGE/METHYLATION
N-TERMINAL DOMAIN
PROTEIN

(Neisseria
subflava) 		PF16732
(ComP_DUS) 		3 ARG A 113
ILE A  64
TRP A  42
 None
 1.16A 3e7iB-2nbaA:
undetectable		 3e7iB-2nbaA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pes URICASE

(Aspergillus
flavus) 		PF01014
(Uricase) 		3 ARG A 128
ILE A 142
TRP A 188
 None
 0.74A 3e7iB-2pesA:
undetectable		 3e7iB-2pesA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qi2 CELL DIVISION
PROTEIN PELOTA
RELATED PROTEIN

(Thermoplasma
acidophilum) 		PF03463
(eRF1_1)
PF03465
(eRF1_3) 		3 ARG A 293
ILE A  70
TRP A  24
 None
 0.95A 3e7iB-2qi2A:
undetectable		 3e7iB-2qi2A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7g UROCANATE HYDRATASE

(Pseudomonas
putida) 		PF01175
(Urocanase)
PF17391
(Urocanase_N)
PF17392
(Urocanase_C) 		3 ARG A 418
ILE A 410
TRP A 412
 None
 0.83A 3e7iB-2v7gA:
undetectable		 3e7iB-2v7gA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wtb FATTY ACID
MULTIFUNCTIONAL
PROTEIN (ATMFP2)

(Arabidopsis
thaliana) 		PF00378
(ECH_1)
PF00725
(3HCDH)
PF02737
(3HCDH_N) 		3 ARG A 127
ILE A 204
TRP A 200
 None
 1.06A 3e7iB-2wtbA:
undetectable		 3e7iB-2wtbA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z2r NUCLEOSOME ASSEMBLY
PROTEIN

(Saccharomyces
cerevisiae) 		PF00956
(NAP) 		3 ARG A 355
ILE A 131
TRP A 132
 None
 1.00A 3e7iB-2z2rA:
undetectable		 3e7iB-2z2rA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cji POLYPROTEIN

(Senecavirus A) 		no annotation 3 ARG A 169
ILE A 217
TRP A 140
 None
 1.11A 3e7iB-3cjiA:
undetectable		 3e7iB-3cjiA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cwv DNA GYRASE, B
SUBUNIT, TRUNCATED

(Myxococcus
xanthus) 		PF00204
(DNA_gyraseB) 		3 ARG A 120
ILE A 115
TRP A 122
 None
 1.08A 3e7iB-3cwvA:
undetectable		 3e7iB-3cwvA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfr DIHYDROFOLATE
REDUCTASE

(Lactobacillus
casei) 		PF00186
(DHFR_1) 		3 ARG A 117
ILE A  13
TRP A   5
 None
NDP  A 163 (-3.8A)
None
 0.96A 3e7iB-3dfrA:
undetectable		 3e7iB-3dfrA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dko EPHRIN TYPE-A
RECEPTOR 7

(Homo sapiens) 		PF07714
(Pkinase_Tyr)
PF14575
(EphA2_TM) 		3 ARG A 835
ILE A 824
TRP A 802
 None
 1.13A 3e7iB-3dkoA:
undetectable		 3e7iB-3dkoA:
19.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3e7g NITRIC OXIDE
SYNTHASE, INDUCIBLE

(Homo sapiens) 		PF02898
(NO_synthase) 		3 ARG A 381
ILE A 462
TRP A 463
 H4B  A 902 (-3.9A)
H4B  A 902 (-4.9A)
H4B  A 902 ( 3.6A)
 0.34A 3e7iB-3e7gA:
59.1		 3e7iB-3e7gA:
87.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f9k INTEGRASE

(Human
immunodeficiency
virus 2) 		PF00665
(rve)
PF02022
(Integrase_Zn) 		3 ARG A 107
ILE A 110
TRP A  61
 None
 1.00A 3e7iB-3f9kA:
undetectable		 3e7iB-3f9kA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gbd SUCROSE ISOMERASE
SMUA FROM
PROTAMINOBACTER
RUBRUM

(Serratia
plymuthica) 		PF00128
(Alpha-amylase)
PF16657
(Malt_amylase_C) 		3 ARG A 485
ILE A 290
TRP A 333
 None
 1.01A 3e7iB-3gbdA:
undetectable		 3e7iB-3gbdA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		3 ARG A1055
ILE A1115
TRP A1064
 None
 1.17A 3e7iB-3jb9A:
undetectable		 3e7iB-3jb9A:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jq3 LOMBRICINE KINASE

(Urechis caupo) 		PF00217
(ATP-gua_Ptrans)
PF02807
(ATP-gua_PtransN) 		3 ARG A 117
ILE A 214
TRP A 215
 ADP  A 400 (-2.6A)
None
None
 0.89A 3e7iB-3jq3A:
undetectable		 3e7iB-3jq3A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k30 HISTAMINE
DEHYDROGENASE

(Pimelobacter
simplex) 		PF00724
(Oxidored_FMN)
PF07992
(Pyr_redox_2) 		3 ARG A 429
ILE A 349
TRP A 442
 None
SF4  A 801 (-4.1A)
None
 1.14A 3e7iB-3k30A:
undetectable		 3e7iB-3k30A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m1u PUTATIVE
GAMMA-D-GLUTAMYL-L-D
IAMINO ACID
ENDOPEPTIDASE

(Desulfovibrio
vulgaris) 		PF00877
(NLPC_P60)
PF12912
(N_NLPC_P60)
PF12913
(SH3_6)
PF12914
(SH3_7) 		3 ARG A 390
ILE A 393
TRP A 388
 None
 1.05A 3e7iB-3m1uA:
undetectable		 3e7iB-3m1uA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3m6m RPFF PROTEIN

(Xanthomonas
campestris) 		PF00378
(ECH_1) 		3 ARG A  24
ILE A  19
TRP A  28
 None
 1.10A 3e7iB-3m6mA:
undetectable		 3e7iB-3m6mA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3opy 6-PHOSPHOFRUCTO-1-KI
NASE ALPHA-SUBUNIT

(Komagataella
pastoris) 		PF00365
(PFK) 		3 ARG A 230
ILE A 237
TRP A 265
 SO4  A 996 (-4.3A)
None
None
 1.09A 3e7iB-3opyA:
undetectable		 3e7iB-3opyA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3rg9 BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE

(Trypanosoma
brucei) 		PF00186
(DHFR_1) 		3 ARG A 183
ILE A  51
TRP A  49
 None
 1.04A 3e7iB-3rg9A:
undetectable		 3e7iB-3rg9A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3s9v ABIETADIENE
SYNTHASE,
CHLOROPLASTIC

(Abies grandis) 		PF01397
(Terpene_synth)
PF03936
(Terpene_synth_C) 		3 ARG A 749
ILE A 685
TRP A 689
 None
 0.92A 3e7iB-3s9vA:
undetectable		 3e7iB-3s9vA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3t6w LACCASE

(Steccherinum
ochraceum) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 122
ILE A 455
TRP A 457
 None
CU  A 501 (-3.8A)
None
 0.88A 3e7iB-3t6wA:
undetectable		 3e7iB-3t6wA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tw5 TRANSGLUTAMINASE
ELICITOR

(Phytophthora
sojae) 		PF16683
(TGase_elicitor) 		3 ARG A 438
ILE A 442
TRP A 441
 None
 1.11A 3e7iB-3tw5A:
undetectable		 3e7iB-3tw5A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3upu ATP-DEPENDENT DNA
HELICASE DDA

(Escherichia
virus T4) 		PF13604
(AAA_30) 		3 ARG A 253
ILE A 342
TRP A 323
 None
 1.15A 3e7iB-3upuA:
undetectable		 3e7iB-3upuA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3v0a NTNH

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		3 ARG B  24
ILE B 201
TRP B 202
 None
 1.11A 3e7iB-3v0aB:
undetectable		 3e7iB-3v0aB:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3w36 NAPH1

(Streptomyces
sp. CNQ525) 		no annotation 3 ARG A 385
ILE A 406
TRP A 411
 None
 0.75A 3e7iB-3w36A:
undetectable		 3e7iB-3w36A:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wxo CATALASE-PEROXIDASE

(Synechococcus
elongatus) 		PF00141
(peroxidase) 		3 ARG A 404
ILE A 431
TRP A 432
 None
 1.14A 3e7iB-3wxoA:
undetectable		 3e7iB-3wxoA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zhc PHYTASE

(Citrobacter
braakii) 		PF00328
(His_Phos_2) 		3 ARG A 158
ILE A 152
TRP A 210
 None
 1.07A 3e7iB-3zhcA:
undetectable		 3e7iB-3zhcA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bed HEMOCYANIN KLH1

(Megathura
crenulata) 		PF00264
(Tyrosinase)
PF14830
(Haemocyan_bet_s) 		3 ARG B2628
ILE B2508
TRP B2593
 None
 1.09A 3e7iB-4bedB:
undetectable		 3e7iB-4bedB:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bxs VENOM PROTHROMBIN
ACTIVATOR
PSEUTARIN-C
NON-CATALYTIC
SUBUNIT

(Pseudonaja
textilis) 		PF00754
(F5_F8_type_C)
PF07732
(Cu-oxidase_3) 		3 ARG V 926
ILE V 961
TRP V 939
 None
 1.10A 3e7iB-4bxsV:
undetectable		 3e7iB-4bxsV:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czx PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2
PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN3

(Neurospora
crassa) 		no annotation 3 ARG A 104
ILE A  64
TRP B 566
 PO4  A 401 (-4.0A)
None
None
 0.95A 3e7iB-4czxA:
undetectable		 3e7iB-4czxA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ddw REVERSE GYRASE

(Thermotoga
maritima) 		PF00270
(DEAD)
PF01131
(Topoisom_bac)
PF01751
(Toprim) 		3 ARG A 931
ILE A 859
TRP A 885
 None
 1.11A 3e7iB-4ddwA:
undetectable		 3e7iB-4ddwA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4g0j NON-STRUCTURAL
PROTEIN 2

(Rotavirus A) 		PF02509
(Rota_NS35) 		3 ARG A 227
ILE A 265
TRP A 269
 None
 0.86A 3e7iB-4g0jA:
undetectable		 3e7iB-4g0jA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iig BETA-GLUCOSIDASE 1

(Aspergillus
aculeatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 ARG A 521
ILE A 548
TRP A 570
 None
 1.08A 3e7iB-4iigA:
undetectable		 3e7iB-4iigA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kh8 HYPOTHETICAL PROTEIN

(Enterococcus
faecalis) 		PF16103
(DUF4822) 		3 ARG A 190
ILE A  89
TRP A  65
 None
 1.13A 3e7iB-4kh8A:
undetectable		 3e7iB-4kh8A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mwf FAB AR3C HEAVY CHAIN

(Homo sapiens) 		PF07654
(C1-set)
PF07686
(V-set) 		3 ARG A  94
ILE A  69
TRP A  36
 None
 1.13A 3e7iB-4mwfA:
undetectable		 3e7iB-4mwfA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4okj 3'-5'
EXORIBONUCLEASE
RV2179C/MT2234.1

(Mycobacterium
tuberculosis) 		PF16473
(DUF5051) 		3 ARG A 135
ILE A 156
TRP A 124
 None
 0.94A 3e7iB-4okjA:
undetectable		 3e7iB-4okjA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4tsk KETOL-ACID
REDUCTOISOMERASE

(Alicyclobacillus
acidocaldarius) 		PF01450
(IlvC)
PF07991
(IlvN) 		3 ARG A  84
ILE A 291
TRP A 290
 None
 1.12A 3e7iB-4tskA:
undetectable		 3e7iB-4tskA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uri CHITINASE-RELATED
AGGLUTININ

(Robinia
pseudoacacia) 		PF00704
(Glyco_hydro_18) 		3 ARG A 135
ILE A 100
TRP A 134
 NA  A 502 ( 4.4A)
None
None
 1.16A 3e7iB-4uriA:
undetectable		 3e7iB-4uriA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zb3 NUDIX HYDROLASE 7

(Arabidopsis
thaliana) 		PF00293
(NUDIX) 		3 ARG A  74
ILE A  53
TRP A  54
 None
 1.10A 3e7iB-4zb3A:
undetectable		 3e7iB-4zb3A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zkt BOTULINUM NEUROTOXIN
TYPE E,
NONTOXIC-NONHEMAGGLU
TININ COMPONENT,
NTNH

(Clostridium
botulinum) 		PF01742
(Peptidase_M27)
PF07953
(Toxin_R_bind_N)
PF08470
(NTNH_C) 		3 ARG B  24
ILE B 168
TRP B 169
 None
 1.09A 3e7iB-4zktB:
undetectable		 3e7iB-4zktB:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxi TYROCIDINE
SYNTHETASE 3

(Acinetobacter
baumannii) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C) 		3 ARG A1164
ILE A1161
TRP A1134
 None
 0.84A 3e7iB-4zxiA:
undetectable		 3e7iB-4zxiA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zxi TYROCIDINE
SYNTHETASE 3

(Acinetobacter
baumannii) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C) 		3 ARG A1164
ILE A1298
TRP A1134
 None
 0.97A 3e7iB-4zxiA:
undetectable		 3e7iB-4zxiA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cs4 ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF08326
(ACC_central) 		3 ARG A1173
ILE A1115
TRP A1131
 None
 0.90A 3e7iB-5cs4A:
undetectable		 3e7iB-5cs4A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5csa ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF00364
(Biotin_lipoyl)
PF08326
(ACC_central) 		3 ARG A1173
ILE A1115
TRP A1131
 None
 1.09A 3e7iB-5csaA:
undetectable		 3e7iB-5csaA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ehf LACCASE

(Antrodiella
faginea) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 121
ILE A 453
TRP A 455
 None
CU  A 510 (-3.7A)
None
 0.91A 3e7iB-5ehfA:
undetectable		 3e7iB-5ehfA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f2v GTP
PYROPHOSPHOKINASE
YJBM

(Bacillus
subtilis) 		no annotation 3 ARG V 143
ILE V 153
TRP V 150
 APC  V 301 ( 4.9A)
None
None
 0.92A 3e7iB-5f2vV:
undetectable		 3e7iB-5f2vV:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fji BETA-GLUCOSIDASE

(Aspergillus
fumigatus) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 ARG A 522
ILE A 549
TRP A 571
 None
 1.11A 3e7iB-5fjiA:
undetectable		 3e7iB-5fjiA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fjj BETA-GLUCOSIDASE

(Aspergillus
oryzae) 		PF00933
(Glyco_hydro_3)
PF01915
(Glyco_hydro_3_C)
PF14310
(Fn3-like) 		3 ARG A 522
ILE A 549
TRP A 571
 None
 1.15A 3e7iB-5fjjA:
undetectable		 3e7iB-5fjjA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5flz TUBULIN GAMMA CHAIN

(Saccharomyces
cerevisiae) 		PF00091
(Tubulin)
PF03953
(Tubulin_C) 		3 ARG C 114
ILE C 119
TRP C  93
 None
 1.10A 3e7iB-5flzC:
undetectable		 3e7iB-5flzC:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fn4 GAMMA-SECRETASE
SUBUNIT APH-1A

(Homo sapiens) 		PF06105
(Aph-1) 		3 ARG C 186
ILE C 230
TRP C 227
 None
 1.14A 3e7iB-5fn4C:
undetectable		 3e7iB-5fn4C:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fsy MACRODOMAIN

(Trypanosoma
brucei) 		PF01661
(Macro) 		3 ARG A 169
ILE A  57
TRP A  76
 None
 1.07A 3e7iB-5fsyA:
undetectable		 3e7iB-5fsyA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzu CHITINASE

(Paenibacillus
sp. FPU-7) 		PF00704
(Glyco_hydro_18) 		3 ARG A1190
ILE A1187
TRP A1176
 None
 1.06A 3e7iB-5gzuA:
undetectable		 3e7iB-5gzuA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h1k GEM-ASSOCIATED
PROTEIN 5

(Homo sapiens) 		PF00400
(WD40)
PF12894
(ANAPC4_WD40) 		3 ARG A 260
ILE A 253
TRP A 254
 None
 1.10A 3e7iB-5h1kA:
undetectable		 3e7iB-5h1kA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i6e ACETYL-COA
CARBOXYLASE

(Saccharomyces
cerevisiae) 		PF08326
(ACC_central) 		3 ARG A1173
ILE A1115
TRP A1131
 SEP  A1157 ( 2.8A)
None
None
 0.85A 3e7iB-5i6eA:
undetectable		 3e7iB-5i6eA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ibv CAPSID POLYPROTEIN
VP90

(Mamastrovirus 1) 		PF03115
(Astro_capsid_N) 		3 ARG A 179
ILE A 102
TRP A 350
 None
 1.13A 3e7iB-5ibvA:
undetectable		 3e7iB-5ibvA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ja1 ENTEROBACTIN
SYNTHASE COMPONENT F

(Escherichia
coli) 		PF00501
(AMP-binding)
PF00550
(PP-binding)
PF00668
(Condensation)
PF00975
(Thioesterase)
PF13193
(AMP-binding_C) 		3 ARG A 623
ILE A 659
TRP A 656
 None
 1.15A 3e7iB-5ja1A:
undetectable		 3e7iB-5ja1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mew LACCASE 2

(Steccherinum
murashkinskyi) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		3 ARG A 122
ILE A 455
TRP A 457
 None
CU  A 504 (-3.8A)
None
 0.92A 3e7iB-5mewA:
undetectable		 3e7iB-5mewA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n77 MAGNESIUM TRANSPORT
PROTEIN CORA

(Escherichia
coli) 		PF01544
(CorA) 		3 ARG A  14
ILE A  29
TRP A  28
 None
 1.10A 3e7iB-5n77A:
undetectable		 3e7iB-5n77A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ojr -

(-) 		no annotation 3 ARG A  82
ILE A  64
TRP A  70
 None
 1.14A 3e7iB-5ojrA:
undetectable		 3e7iB-5ojrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqj RNA POLYMERASE II
TRANSCRIPTION FACTOR
B SUBUNIT 1

(Saccharomyces
cerevisiae) 		no annotation 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.96A 3e7iB-5oqj1:
undetectable		 3e7iB-5oqj1:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oqm GENERAL
TRANSCRIPTION AND
DNA REPAIR FACTOR
IIH SUBUNIT TFB1

(Saccharomyces
cerevisiae) 		no annotation 3 ARG 1  30
ILE 1  16
TRP 1  29
 None
 0.95A 3e7iB-5oqm1:
undetectable		 3e7iB-5oqm1:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5tey N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT

(Homo sapiens) 		PF05063
(MT-A70) 		3 ARG A 508
ILE A 503
TRP A 457
 None
 0.89A 3e7iB-5teyA:
undetectable		 3e7iB-5teyA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uhe DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA'

(Mycobacterium
tuberculosis) 		PF00623
(RNA_pol_Rpb1_2)
PF04983
(RNA_pol_Rpb1_3)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		3 ARG D 113
ILE D 104
TRP D 105
 None
 0.93A 3e7iB-5uheD:
undetectable		 3e7iB-5uheD:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5vf4 UNCHARACTERIZED
PROTEIN

(Thermus
aquaticus) 		PF03781
(FGE-sulfatase) 		3 ARG A 370
ILE A  93
TRP A 201
 None
 1.14A 3e7iB-5vf4A:
undetectable		 3e7iB-5vf4A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ygh CAPSID PROTEIN

(Zika virus) 		no annotation 3 ARG A  55
ILE A  66
TRP A  69
 None
 1.12A 3e7iB-5yghA:
undetectable		 3e7iB-5yghA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5z5d BETA-XYLOSIDASE

(Geobacillus
thermoleovorans) 		no annotation 3 ARG A 142
ILE A 114
TRP A 117
 None
 1.11A 3e7iB-5z5dA:
undetectable		 3e7iB-5z5dA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6br6 NEURAMINIDASE

(Influenza A
virus) 		no annotation 3 ARG A 420
ILE A 233
TRP A  87
 None
 1.16A 3e7iB-6br6A:
undetectable		 3e7iB-6br6A:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6byk 14-3-3 PROTEIN
BETA/ALPHA

(Homo sapiens) 		no annotation 3 ARG A  58
ILE A  88
TRP A  61
 None
 1.09A 3e7iB-6bykA:
undetectable		 3e7iB-6bykA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c7v -

(-) 		no annotation 3 ARG A 202
ILE A  11
TRP A  50
 None
 1.09A 3e7iB-6c7vA:
undetectable		 3e7iB-6c7vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfz ASK1
DAD4

(Chaetomium
thermophilum) 		no annotation 3 ARG A  59
ILE E  44
TRP A  62
 None
 1.02A 3e7iB-6cfzA:
undetectable		 3e7iB-6cfzA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6d2q FERM, RHOGEF
(ARHGEF) AND
PLECKSTRIN DOMAIN
PROTEIN 1
(CHONDROCYTE-DERIVED
)

(Danio rerio) 		no annotation 3 ARG A 149
ILE A 310
TRP A  95
 None
 1.16A 3e7iB-6d2qA:
undetectable		 3e7iB-6d2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN

(Homo sapiens) 		no annotation 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.88A 3e7iB-6ei1A:
undetectable		 3e7iB-6ei1A:
11.46