SIMILAR PATTERNS OF AMINO ACIDS FOR 3E4E_B_4PZB501_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cpt | CYTOCHROME P450-TERP (Pseudomonas sp.) |
PF00067(p450) | 3 | ALA A 267THR A 271CYH A 377 | HEM A 430 (-3.5A)HEM A 430 (-3.7A)HEM A 430 (-2.1A) | 0.39A | 3e4eB-1cptA:29.3 | 3e4eB-1cptA:21.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cqj | SUCCINYL-COASYNTHETASE ALPHACHAIN (Escherichiacoli) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 3 | ALA A 160THR A 164CYH A 174 | None | 0.57A | 3e4eB-1cqjA:undetectable | 3e4eB-1cqjA:21.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1eqn | DNA PRIMASE (Escherichiacoli) |
PF08275(Toprim_N)PF10410(DnaB_bind)PF13155(Toprim_2) | 3 | ALA A 321THR A 289CYH A 306 | None | 0.76A | 3e4eB-1eqnA:undetectable | 3e4eB-1eqnA:22.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gwi | CYTOCHROME P450154C1 (Streptomycescoelicolor) |
PF00067(p450) | 3 | ALA A 242THR A 246CYH A 355 | HEM A1414 ( 3.7A)HEM A1414 (-3.7A)HEM A1414 (-2.5A) | 0.44A | 3e4eB-1gwiA:28.1 | 3e4eB-1gwiA:24.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hg2 | CLATHRIN ASSEMBLYPROTEIN SHORT FORM (Rattusnorvegicus) |
PF07651(ANTH) | 3 | ALA A 21THR A 25CYH A 48 | None | 0.75A | 3e4eB-1hg2A:undetectable | 3e4eB-1hg2A:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n97 | CYP175A1 (Thermusthermophilus) |
PF00067(p450) | 3 | ALA A 221THR A 225CYH A 336 | HEM A 602 (-3.3A)HEM A 602 (-3.8A)HEM A 602 (-2.2A) | 0.48A | 3e4eB-1n97A:32.0 | 3e4eB-1n97A:26.19 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1nr6 | CYTOCHROME P450 2C5 (Oryctolaguscuniculus) |
PF00067(p450) | 3 | ALA A 294THR A 298CYH A 432 | DIF A 501 ( 3.3A)HEM A 500 ( 3.6A)HEM A 500 (-2.3A) | 0.41A | 3e4eB-1nr6A:51.5 | 3e4eB-1nr6A:57.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1odo | PUTATIVE CYTOCHROMEP450 154A1 (Streptomycescoelicolor) |
PF00067(p450) | 3 | ALA A 242THR A 246CYH A 354 | HEM A1407 ( 3.4A)HEM A1407 ( 3.1A)HEM A1407 (-2.3A) | 0.44A | 3e4eB-1odoA:31.1 | 3e4eB-1odoA:22.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q5d | P450 EPOXIDASE (Sorangiumcellulosum) |
PF00067(p450) | 3 | ALA A 254THR A 258CYH A 365 | HEM A 440 (-3.4A)HEM A 440 ( 3.8A)HEM A 440 (-2.3A) | 0.45A | 3e4eB-1q5dA:29.5 | 3e4eB-1q5dA:25.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ue8 | 367AA LONGHYPOTHETICALCYTOCHROME P450 (Sulfurisphaeratokodaii) |
PF00067(p450) | 3 | ALA A 210THR A 214CYH A 317 | HEM A 410 (-4.2A)HEM A 410 (-4.1A)HEM A 410 (-2.3A) | 0.38A | 3e4eB-1ue8A:30.8 | 3e4eB-1ue8A:25.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vlp | NICOTINATEPHOSPHORIBOSYLTRANSFERASE (Saccharomycescerevisiae) |
PF04095(NAPRTase) | 3 | ALA A 22THR A 25CYH A 255 | None | 0.77A | 3e4eB-1vlpA:undetectable | 3e4eB-1vlpA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wfm | SYNAPTOTAGMIN XIII (Homo sapiens) |
PF00168(C2) | 3 | ALA A 35THR A 37CYH A 46 | None | 0.44A | 3e4eB-1wfmA:undetectable | 3e4eB-1wfmA:14.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1x8v | CYTOCHROME P450 51 (Mycobacteriumtuberculosis) |
PF00067(p450) | 3 | ALA A 256THR A 260CYH A 394 | ESL A 471 ( 3.4A)HEM A 470 (-3.6A)HEM A 470 (-2.4A) | 0.42A | 3e4eB-1x8vA:31.6 | 3e4eB-1x8vA:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2azp | HYPOTHETICAL PROTEINPA1268 (Pseudomonasaeruginosa) |
PF05544(Pro_racemase) | 3 | ALA A 62THR A 16CYH A 88 | None | 0.72A | 3e4eB-2azpA:undetectable | 3e4eB-2azpA:20.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2f9q | CYTOCHROME P450 2D6 (Homo sapiens) |
PF00067(p450) | 3 | ALA A 305THR A 309CYH A 443 | HEM A 600 (-3.6A)HEM A 600 (-3.5A)HEM A 600 (-2.4A) | 0.31A | 3e4eB-2f9qA:44.2 | 3e4eB-2f9qA:41.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fpg | SUCCINYL-COA LIGASE[GDP-FORMING]ALPHA-CHAIN,MITOCHONDRIAL (Sus scrofa) |
PF00549(Ligase_CoA)PF02629(CoA_binding) | 3 | ALA A 169THR A 173CYH A 183 | None | 0.61A | 3e4eB-2fpgA:undetectable | 3e4eB-2fpgA:19.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ftr | BH0200 (Bacillushalodurans) |
PF07110(EthD) | 3 | ALA A 32THR A 35CYH A 63 | NoneUNL A 109 (-3.7A) CL A 108 (-3.8A) | 0.59A | 3e4eB-2ftrA:undetectable | 3e4eB-2ftrA:11.76 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2hi4 | CYTOCHROME P450 1A2 (Homo sapiens) |
PF00067(p450) | 3 | ALA A 317THR A 321CYH A 458 | HEM A 900 ( 3.5A)HEM A 900 ( 3.1A)HEM A 900 (-2.3A) | 0.42A | 3e4eB-2hi4A:43.2 | 3e4eB-2hi4A:32.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2nnj | CYTOCHROME P450 2C8 (Homo sapiens) |
PF00067(p450) | 3 | ALA A 297THR A 301CYH A 435 | HEM A 500 (-3.5A)HEM A 500 ( 3.7A)HEM A 500 (-2.3A) | 0.46A | 3e4eB-2nnjA:52.5 | 3e4eB-2nnjA:59.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2q9g | CYTOCHROME P450 46A1 (Homo sapiens) |
PF00067(p450) | 3 | ALA A 302THR A 306CYH A 437 | HEM A 505 (-3.7A)HEM A 505 (-3.7A)HEM A 505 (-2.3A) | 0.33A | 3e4eB-2q9gA:34.8 | 3e4eB-2q9gA:27.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ve3 | PUTATIVE CYTOCHROMEP450 120 (Synechocystissp. PCC 6803) |
PF00067(p450) | 3 | ALA A 254THR A 258CYH A 391 | HEM A1444 (-3.3A)HEM A1444 ( 3.3A)HEM A1444 (-2.5A) | 0.53A | 3e4eB-2ve3A:35.0 | 3e4eB-2ve3A:25.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wgy | CYTOCHROME P450 130 (Mycobacteriumtuberculosis) |
PF00067(p450) | 3 | ALA A 243THR A 247CYH A 354 | HEM A 450 (-3.5A)HEM A 450 (-3.6A)HEM A 450 (-2.2A) | 0.48A | 3e4eB-2wgyA:27.8 | 3e4eB-2wgyA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wm4 | PUTATIVE CYTOCHROMEP450 124 (Mycobacteriumtuberculosis) |
PF00067(p450) | 3 | ALA A 267THR A 271CYH A 379 | HEM A 450 (-3.3A)HEM A 450 (-3.1A)HEM A 450 (-2.3A) | 0.41A | 3e4eB-2wm4A:29.9 | 3e4eB-2wm4A:23.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xn8 | PUTATIVE CYTOCHROMEP450 125 (Mycobacteriumtuberculosis) |
PF00067(p450) | 3 | ALA A 268THR A 272CYH A 377 | HEM A1434 (-3.5A)HEM A1434 (-3.8A)HEM A1434 (-2.3A) | 0.52A | 3e4eB-2xn8A:27.7 | 3e4eB-2xn8A:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z36 | CYTOCHROME P450 TYPECOMPACTIN3'',4''-HYDROXYLASE (Nonomuraearecticatena) |
PF00067(p450) | 3 | ALA A 245THR A 249CYH A 356 | HEM A 450 ( 3.9A)HEM A 450 ( 3.7A)HEM A 450 ( 2.6A) | 0.44A | 3e4eB-2z36A:29.2 | 3e4eB-2z36A:26.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z3t | CYTOCHROME P450 (Streptomycessp. TP-A0274) |
PF00067(p450) | 3 | ALA A 254THR A 258CYH A 364 | HEM A 500 ( 3.4A)HEM A 500 ( 3.4A)HEM A 500 (-2.5A) | 0.56A | 3e4eB-2z3tA:30.5 | 3e4eB-2z3tA:24.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbz | CYTOCHROME P450-SU1 (Streptomycesgriseolus) |
PF00067(p450) | 3 | ALA A 244THR A 248CYH A 355 | HEM A 413 (-3.5A)HEM A 413 (-3.2A)HEM A 413 (-2.3A) | 0.49A | 3e4eB-2zbzA:32.6 | 3e4eB-2zbzA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3abb | CYTOCHROME P450HYDROXYLASE (Streptomycesavermitilis) |
PF00067(p450) | 3 | ALA A 243THR A 247CYH A 353 | HEM A1430 (-3.5A)HEM A1430 (-4.0A)HEM A1430 (-2.3A) | 0.48A | 3e4eB-3abbA:30.9 | 3e4eB-3abbA:25.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3c6g | CYTOCHROME P450 2R1 (Homo sapiens) |
PF00067(p450) | 3 | ALA A 310THR A 314CYH A 448 | HEM A 601 (-3.3A)HEM A 601 (-3.4A)HEM A 601 (-2.1A) | 0.25A | 3e4eB-3c6gA:48.8 | 3e4eB-3c6gA:37.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ejb | BIOTIN BIOSYNTHESISCYTOCHROME P450-LIKEENZYME (Bacillussubtilis) |
PF00067(p450) | 3 | ALA B 234THR B 238CYH B 344 | HEM B 405 (-3.5A)HEM B 405 (-3.7A)HEM B 405 (-2.3A) | 0.40A | 3e4eB-3ejbB:33.2 | 3e4eB-3ejbB:24.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fd5 | SELENIDE, WATERDIKINASE 1 (Homo sapiens) |
PF00586(AIRS)PF02769(AIRS_C) | 3 | ALA A 155THR A 157CYH A 104 | None | 0.64A | 3e4eB-3fd5A:undetectable | 3e4eB-3fd5A:21.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jsk | CYPBP37 PROTEIN (Neurosporacrassa) |
PF01946(Thi4) | 3 | ALA A 326THR A 289CYH A 90 | NoneNoneAHZ A 500 (-4.9A) | 0.59A | 3e4eB-3jskA:undetectable | 3e4eB-3jskA:20.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k9y | 1,25-DIHYDROXYVITAMIN D(3)24-HYDROXYLASE,MITOCHONDRIAL (Rattusnorvegicus) |
PF00067(p450) | 3 | ALA A 326THR A 330CYH A 462 | HEM A 520 ( 3.3A)HEM A 520 ( 3.8A)HEM A 520 ( 2.2A) | 0.47A | 3e4eB-3k9yA:32.5 | 3e4eB-3k9yA:28.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ksw | STEROL 14-ALPHADEMETHYLASE (Trypanosomacruzi) |
PF00067(p450) | 3 | ALA A 291THR A 295CYH A 422 | VNF A 490 ( 4.0A)VNF A 490 ( 4.0A)HEM A 488 (-2.2A) | 0.74A | 3e4eB-3kswA:26.0 | 3e4eB-3kswA:26.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l4d | STEROL 14-ALPHADEMETHYLASE (Leishmaniainfantum) |
PF00067(p450) | 3 | ALA A 290THR A 294CYH A 422 | TPF A 490 ( 3.4A)TPF A 490 ( 3.5A)HEM A 481 (-2.2A) | 0.33A | 3e4eB-3l4dA:31.1 | 3e4eB-3l4dA:26.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mqt | MANDELATERACEMASE/MUCONATELACTONIZING PROTEIN (Shewanellapealeana) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 3 | ALA A 217THR A 220CYH A 207 | None | 0.73A | 3e4eB-3mqtA:undetectable | 3e4eB-3mqtA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p3l | CYTOCHROME P450 (Streptomycesthioluteus) |
PF00067(p450) | 3 | ALA A 243THR A 247CYH A 355 | HEM A 501 (-3.5A)HEM A 501 (-3.6A)HEM A 501 (-2.4A) | 0.33A | 3e4eB-3p3lA:27.8 | 3e4eB-3p3lA:25.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3pm0 | CYTOCHROME P450 1B1 (Homo sapiens) |
PF00067(p450) | 3 | ALA A 330THR A 334CYH A 470 | HEM A 900 ( 3.4A)HEM A 900 ( 3.2A)HEM A 900 (-2.3A) | 0.41A | 3e4eB-3pm0A:41.8 | 3e4eB-3pm0A:33.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3r9b | CYTOCHROME P450164A2 (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 3 | ALA A 256THR A 260CYH A 366 | HEM A 501 ( 3.5A)HEM A 501 (-3.4A)HEM A 501 (-2.3A) | 0.58A | 3e4eB-3r9bA:31.1 | 3e4eB-3r9bA:24.75 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3tk3 | CYTOCHROME P450 2B4 (Oryctolaguscuniculus) |
PF00067(p450) | 3 | ALA A 298THR A 302CYH A 436 | CPZ A 501 (-3.5A)CPZ A 501 ( 3.7A)HEM A 500 (-2.3A) | 0.55A | 3e4eB-3tk3A:54.3 | 3e4eB-3tk3A:49.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tkt | CYTOCHROME P450 (Novosphingobiumaromaticivorans) |
PF00067(p450) | 3 | ALA A 269THR A 273CYH A 379 | HEM A 431 (-3.5A)HEM A 431 (-3.8A)HEM A 431 (-2.2A) | 0.46A | 3e4eB-3tktA:29.8 | 3e4eB-3tktA:24.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wec | CYTOCHROME P450 (Rhodococcuserythropolis) |
PF00067(p450) | 3 | ALA A 253THR A 257CYH A 361 | HEM A 501 ( 3.5A)HEM A 501 (-3.5A)HEM A 501 (-2.3A) | 0.43A | 3e4eB-3wecA:28.7 | 3e4eB-3wecA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wvs | PUTATIVEMONOOXYGENASE (Streptomycessp. SN-593) |
PF00067(p450) | 3 | ALA A 241THR A 245CYH A 353 | HEM A 501 (-3.8A)HEM A 501 (-3.3A)HEM A 501 (-2.3A) | 0.58A | 3e4eB-3wvsA:30.1 | 3e4eB-3wvsA:25.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zid | TUBULIN/FTSZ, GTPASE (Methanothrixthermoacetophila) |
PF00091(Tubulin) | 3 | ALA A 141THR A 110CYH A 159 | None | 0.62A | 3e4eB-3zidA:undetectable | 3e4eB-3zidA:23.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e2p | CYTOCHROME P450107B1 (P450CVIIB1) (Streptomyceshimastatinicus) |
PF00067(p450) | 3 | ALA A 236THR A 240CYH A 346 | HEM A 401 (-2.9A)HEM A 401 (-3.3A)HEM A 401 (-2.2A) | 0.54A | 3e4eB-4e2pA:29.7 | 3e4eB-4e2pA:24.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fxb | PUTATIVE CYTOCHROMEP450 (Streptomycescoelicolor) |
PF00067(p450) | 3 | ALA A 249THR A 253CYH A 360 | HEM A 501 (-3.1A)HEM A 501 (-3.9A)HEM A 501 (-2.1A) | 0.49A | 3e4eB-4fxbA:27.7 | 3e4eB-4fxbA:25.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g3j | STEROL14-ALPHA-DEMETHYLASE (Trypanosomabrucei) |
PF00067(p450) | 3 | ALA A 291THR A 295CYH A 422 | HEM A 501 ( 3.5A)VNT A 502 ( 3.2A)HEM A 501 (-2.3A) | 0.36A | 3e4eB-4g3jA:31.6 | 3e4eB-4g3jA:25.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4i8v | CYTOCHROME P450 1A1 (Homo sapiens) |
PF00067(p450) | 3 | ALA A 317THR A 321CYH A 457 | BHF A 602 ( 3.4A)HEM A 601 (-3.4A)HEM A 601 (-2.1A) | 0.34A | 3e4eB-4i8vA:44.8 | 3e4eB-4i8vA:35.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4irx | SUGAR ABCTRANSPORTER,PERIPLASMICSUGAR-BINDINGPROTEIN (Caulobactervibrioides) |
PF13407(Peripla_BP_4) | 3 | ALA A 208THR A 212CYH A 229 | None | 0.77A | 3e4eB-4irxA:undetectable | 3e4eB-4irxA:20.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j6c | CYTOCHROME P450MONOOXYGENASE (Nocardiafarcinica) |
PF00067(p450) | 3 | ALA A 244THR A 248CYH A 357 | HEM A 502 (-3.2A)HEM A 502 ( 3.4A)HEM A 502 (-2.2A) | 0.35A | 3e4eB-4j6cA:30.7 | 3e4eB-4j6cA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4j9w | PROLINE RACEMASEFAMILY PROTEIN (Pseudomonasprotegens) |
PF05544(Pro_racemase) | 3 | ALA A 62THR A 16CYH A 88 | NoneNonePYC A 402 (-3.7A) | 0.72A | 3e4eB-4j9wA:undetectable | 3e4eB-4j9wA:22.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jbd | PROLINE RACEMASE (Pseudomonasputida) |
PF05544(Pro_racemase) | 3 | ALA A 62THR A 16CYH A 88 | NoneNoneCIT A 401 (-3.8A) | 0.77A | 3e4eB-4jbdA:undetectable | 3e4eB-4jbdA:21.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jci | PROLINE RACEMASE (Chromohalobactersalexigens) |
PF05544(Pro_racemase) | 3 | ALA A 62THR A 16CYH A 88 | None | 0.72A | 3e4eB-4jciA:undetectable | 3e4eB-4jciA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4juu | EPIMERASE (Xanthomonascampestris) |
PF05544(Pro_racemase) | 3 | ALA A 62THR A 16CYH A 88 | NoneNonePO4 A 404 ( 4.0A) | 0.76A | 3e4eB-4juuA:undetectable | 3e4eB-4juuA:20.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kq8 | CYTOCHROME P450 19A1 (Homo sapiens) |
PF00067(p450) | 3 | ALA A 306THR A 310CYH A 437 | HEM A 601 ( 3.6A)ASD A 602 (-3.9A)HEM A 601 (-2.3A) | 0.69A | 3e4eB-4kq8A:37.0 | 3e4eB-4kq8A:28.71 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4nky | STEROID17-ALPHA-HYDROXYLASE/17,20 LYASE (Homo sapiens) |
PF00067(p450) | 3 | ALA A 302THR A 306CYH A 442 | 3QZ A 601 (-2.9A)HEM A 600 ( 3.2A)HEM A 600 (-2.6A) | 0.60A | 3e4eB-4nkyA:41.0 | 3e4eB-4nkyA:31.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqr | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 3 | ALA A 240THR A 244CYH A 348 | HEM A 501 (-3.5A)HEM A 501 (-3.1A)HEM A 501 (-2.4A) | 0.55A | 3e4eB-4oqrA:31.8 | 3e4eB-4oqrA:23.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4oqs | CYP105AS1 (Amycolatopsisorientalis) |
PF00067(p450) | 3 | ALA A 240THR A 244CYH A 348 | HEM A 501 (-3.4A)HEM A 501 (-3.6A)HEM A 501 (-2.3A) | 0.44A | 3e4eB-4oqsA:29.5 | 3e4eB-4oqsA:23.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r1z | CYP17A1 PROTEIN (Danio rerio) |
PF00067(p450) | 3 | ALA A 313THR A 317CYH A 453 | HEM A 600 (-3.5A)HEM A 600 ( 3.3A)HEM A 600 (-2.3A) | 0.61A | 3e4eB-4r1zA:42.2 | 3e4eB-4r1zA:31.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4r20 | CYTOCHROME P450FAMILY 17POLYPEPTIDE 2 (Danio rerio) |
PF00067(p450) | 3 | ALA A 302THR A 306CYH A 440 | HEM A 601 (-3.4A)HEM A 601 ( 3.3A)HEM A 601 (-2.2A) | 0.55A | 3e4eB-4r20A:42.1 | 3e4eB-4r20A:35.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rm4 | CYTOCHROME P450 (Bacillussubtilis) |
PF00067(p450) | 3 | ALA A 239THR A 243CYH A 349 | HEM A 401 (-3.6A)HEM A 401 (-3.7A)HEM A 401 (-2.3A) | 0.45A | 3e4eB-4rm4A:30.1 | 3e4eB-4rm4A:25.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tnm | IMPORTIN SUBUNITALPHA (Arabidopsisthaliana) |
PF00514(Arm)PF01749(IBB)PF16186(Arm_3) | 3 | ALA A 438THR A 400CYH A 416 | None | 0.71A | 3e4eB-4tnmA:undetectable | 3e4eB-4tnmA:21.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tpn | PUTATIVE P450-LIKEPROTEIN (Streptomycesscabiei) |
PF00067(p450) | 3 | ALA A 245THR A 250CYH A 357 | HEM A 501 (-3.4A)HEM A 501 (-3.9A)HEM A 501 (-2.4A) | 0.70A | 3e4eB-4tpnA:28.5 | 3e4eB-4tpnA:24.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ubs | PENTALENIC ACIDSYNTHASE (Streptomycesavermitilis) |
PF00067(p450) | 3 | ALA A 241THR A 245CYH A 351 | HEM A 501 ( 3.8A)HEM A 501 ( 3.3A)HEM A 501 (-2.4A) | 0.59A | 3e4eB-4ubsA:31.7 | 3e4eB-4ubsA:25.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uhi | STEROL 14-ALPHADEMETHYLASE (Homo sapiens) |
PF00067(p450) | 3 | ALA A 311THR A 315CYH A 449 | HEM A 540 ( 3.4A)HEM A 540 (-3.6A)HEM A 540 (-2.3A) | 0.47A | 3e4eB-4uhiA:32.4 | 3e4eB-4uhiA:25.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4umz | CYTOCHROME P450HYDROXYLASE PIKC (Streptomycesvenezuelae) |
PF00067(p450) | 3 | ALA A 243THR A 247CYH A 354 | HEM A1407 (-3.6A)HEM A1407 (-3.8A)HEM A1407 (-2.1A) | 0.29A | 3e4eB-4umzA:31.8 | 3e4eB-4umzA:23.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wpz | CYTOCHROME P450 (Streptomycesavermitilis) |
PF00067(p450) | 3 | ALA A 239THR A 243CYH A 353 | HEM A 503 (-3.4A)HEM A 503 (-3.9A)HEM A 503 (-2.4A) | 0.54A | 3e4eB-4wpzA:30.1 | 3e4eB-4wpzA:25.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xe3 | CYTOCHROME P-450 (Streptomycesantibioticus) |
PF00067(p450) | 3 | ALA A 244THR A 248CYH A 356 | HEM A 501 ( 3.5A)CL6 A 502 (-3.6A)HEM A 501 (-2.2A) | 0.49A | 3e4eB-4xe3A:23.6 | 3e4eB-4xe3A:22.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yxt | POLYKETIDEBIOSYNTHESIS3-HYDROXY-3-METHYLGLUTARYL-ACP SYNTHASEPKSG (Bacillussubtilis) |
PF01154(HMG_CoA_synt_N)PF08540(HMG_CoA_synt_C) | 3 | ALA A 305THR A 309CYH A 323 | None | 0.70A | 3e4eB-4yxtA:undetectable | 3e4eB-4yxtA:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z5p | CYTOCHROME P450HYDROXYLASE (Streptomycesatroolivaceus) |
PF00067(p450) | 3 | ALA A 236THR A 240CYH A 348 | HEM A 401 (-3.9A)HEM A 401 (-4.5A)HEM A 401 (-2.4A) | 0.57A | 3e4eB-4z5pA:25.1 | 3e4eB-4z5pA:24.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cwe | CYTOCHROME P450HYDROXYLASE (Streptomycesavermitilis) |
PF00067(p450) | 3 | ALA A 233THR A 237CYH A 344 | DAO A 402 (-3.6A)HEM A 403 ( 3.6A)HEM A 403 (-2.0A) | 0.31A | 3e4eB-5cweA:32.3 | 3e4eB-5cweA:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dqn | CYTOCHROME P450CYP125 (Mycolicibacteriumsmegmatis) |
PF00067(p450) | 3 | ALA A 251THR A 255CYH A 360 | 1PE A 505 ( 3.4A)HEM A 501 (-3.8A)HEM A 501 (-2.3A) | 0.46A | 3e4eB-5dqnA:28.4 | 3e4eB-5dqnA:25.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e78 | BIFUNCTIONALP-450/NADPH-P450REDUCTASE (Bacillusmegaterium) |
PF00067(p450) | 3 | ALA A 264THR A 268CYH A 400 | HEM A 501 (-3.6A)HEM A 501 (-3.4A)HEM A 501 (-2.2A) | 0.41A | 3e4eB-5e78A:34.0 | 3e4eB-5e78A:26.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5foi | MYCINAMICIN VIII C21METHYL HYDROXYLASE (Micromonosporagriseorubida) |
PF00067(p450) | 3 | ALA A 227THR A 231CYH A 337 | HEM A 413 ( 3.7A)HEM A 413 (-3.6A)HEM A 413 (-2.1A) | 0.37A | 3e4eB-5foiA:32.7 | 3e4eB-5foiA:24.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5g | PUTATIVE XANTHINEDEHYDROGENASE YAGSFAD-BINDING SUBUNIT (Escherichiacoli) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 3 | ALA C 252THR C 208CYH C 216 | None | 0.78A | 3e4eB-5g5gC:undetectable | 3e4eB-5g5gC:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gnm | VITAMIN D(3)25-HYDROXYLASE (Pseudonocardiaautotrophica) |
PF00067(p450) | 3 | ALA A 236THR A 240CYH A 347 | HEM A 501 (-3.6A)HEM A 501 (-3.7A)HEM A 501 (-2.6A) | 0.46A | 3e4eB-5gnmA:29.7 | 3e4eB-5gnmA:27.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gwe | CYTOCHROME P450 (Corynebacteriumglutamicum) |
PF00067(p450) | 3 | ALA A 292THR A 296CYH A 403 | GWM A 502 ( 3.6A)HEM A 501 (-3.6A)HEM A 501 (-2.3A) | 0.34A | 3e4eB-5gweA:31.9 | 3e4eB-5gweA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iki | CYTOCHROME P450(MEG) (Bacillusmegaterium) |
PF00067(p450) | 3 | ALA A 243THR A 247CYH A 355 | HEM A 501 (-3.5A)HEM A 501 (-3.7A)HEM A 501 (-2.2A) | 0.46A | 3e4eB-5ikiA:27.7 | 3e4eB-5ikiA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) |
PF00067(p450) | 3 | ALA A 237THR A 241CYH A 348 | HEM A 401 (-3.5A)HEM A 401 (-3.8A)HEM A 401 (-2.5A) | 0.50A | 3e4eB-5it1A:30.8 | 3e4eB-5it1A:24.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) |
PF00067(p450) | 3 | ALA A 238THR A 241CYH A 348 | HEM A 401 (-3.1A)HEM A 401 (-3.8A)HEM A 401 (-2.5A) | 0.77A | 3e4eB-5it1A:30.8 | 3e4eB-5it1A:24.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l94 | CYTOCHROME P450 (Bacillusmegaterium) |
PF00067(p450) | 3 | ALA A 242THR A 246CYH A 352 | HEM A 501 (-3.5A)HEM A 501 (-3.4A)HEM A 501 (-2.3A) | 0.63A | 3e4eB-5l94A:28.2 | 3e4eB-5l94A:24.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nji | PHTHIOCEROL/PHENOLPHTHIOCEROL SYNTHESISPOLYKETIDE SYNTHASETYPE I PPSC (Mycobacteriumtuberculosis) |
PF14765(PS-DH) | 3 | ALA A 979THR A 983CYH A1022 | None | 0.65A | 3e4eB-5njiA:undetectable | 3e4eB-5njiA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nws | SAACMM (Streptomycesantibioticus) |
no annotation | 3 | ALA A 267THR A 271CYH A 382 | HEM A 504 (-3.4A)HEM A 504 (-3.9A)HEM A 504 (-2.3A) | 0.44A | 3e4eB-5nwsA:30.1 | 3e4eB-5nwsA:11.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ofq | CYTOCHROME P450 (Bacillusmegaterium) |
PF00067(p450) | 3 | ALA A 241THR A 245CYH A 351 | HEM A 501 (-3.5A)HEM A 501 (-3.7A)HEM A 501 (-2.2A) | 0.45A | 3e4eB-5ofqA:30.3 | 3e4eB-5ofqA:25.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5u6u | CYTOCHROME P450 (Rhodopseudomonaspalustris) |
no annotation | 3 | ALA A 248THR A 252CYH A 358 | HEM A 501 ( 3.3A)HEM A 501 (-3.6A)HEM A 501 (-2.3A) | 0.39A | 3e4eB-5u6uA:28.5 | 3e4eB-5u6uA:11.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5udb | CELL DIVISIONCONTROL PROTEIN 6 (Saccharomycescerevisiae) |
PF09079(Cdc6_C)PF13401(AAA_22) | 3 | ALA 9 443THR 9 447CYH 9 419 | None | 0.68A | 3e4eB-5udb9:undetectable | 3e4eB-5udb9:23.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5veu | CYTOCHROME P450 3A5 (Homo sapiens) |
no annotation | 3 | ALA A 305THR A 309CYH A 441 | HEM A 601 (-3.4A)HEM A 601 ( 3.5A)HEM A 601 (-2.2A) | 0.66A | 3e4eB-5veuA:37.2 | 3e4eB-5veuA:30.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vws | CYTOCHROME P450 (Thermobisporabispora) |
PF00067(p450) | 3 | ALA A 230THR A 234CYH A 340 | HEM A 401 (-3.5A)HEM A 401 (-3.7A)HEM A 401 (-2.3A) | 0.39A | 3e4eB-5vwsA:30.2 | 3e4eB-5vwsA:26.69 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5wbg | CYTOCHROME P450 2B6 (Homo sapiens) |
no annotation | 3 | ALA A 298THR A 302CYH A 436 | 9ZJ A 502 ( 3.5A)9ZJ A 502 ( 3.9A)HEM A 501 (-2.0A) | 0.32A | 3e4eB-5wbgA:54.8 | 3e4eB-5wbgA:56.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xjn | CYTOCHROME P450 (Corynebacteriumglutamicum) |
PF00067(p450) | 3 | ALA A 265THR A 269CYH A 376 | 88L A 501 ( 3.1A)HEM A 502 (-3.5A)HEM A 502 (-2.4A) | 0.31A | 3e4eB-5xjnA:31.8 | 3e4eB-5xjnA:22.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5xxi | CYTOCHROME P450 2C9 (Homo sapiens) |
no annotation | 3 | ALA A 297THR A 301CYH A 435 | LSN A 501 ( 3.3A)HEM A 504 (-4.0A)HEM A 504 (-2.4A) | 0.69A | 3e4eB-5xxiA:44.3 | 3e4eB-5xxiA:58.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y1i | CYTOCHROME P450 (Streptomycesgraminofaciens) |
PF00067(p450) | 3 | ALA A 248THR A 252CYH A 363 | HEM A 501 (-3.4A)HEM A 501 (-3.9A)HEM A 501 (-2.1A) | 0.42A | 3e4eB-5y1iA:31.2 | 3e4eB-5y1iA:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ysm | CYTOCHROME P450 (Amycolatopsismediterranei) |
no annotation | 3 | ALA A 256THR A 260CYH A 366 | HEM A 501 (-3.4A)HEM A 501 (-3.7A)HEM A 501 (-2.3A) | 0.45A | 3e4eB-5ysmA:31.0 | 3e4eB-5ysmA:11.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ay4 | CYP51, STEROL14ALPHA-DEMETHYLASE (Naegleriafowleri) |
no annotation | 3 | ALA A 293THR A 297CYH A 430 | TPF A 506 ( 3.2A)HEM A 501 (-3.4A)HEM A 501 ( 1.8A) | 0.44A | 3e4eB-6ay4A:31.9 | 3e4eB-6ay4A:28.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6b82 | CYTOCHROME P450,FAMILY 17, SUBFAMILYA, POLYPEPTIDE 1 (Danio rerio) |
no annotation | 3 | ALA A 313THR A 317CYH A 453 | HEM A 601 (-3.6A)HEM A 601 ( 3.7A)HEM A 601 (-2.3A) | 0.68A | 3e4eB-6b82A:44.1 | 3e4eB-6b82A:10.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6bld | CYTOCHROME P450268A2 CYP268A2 (Mycobacteriummarinum) |
no annotation | 3 | ALA A 260THR A 264CYH A 372 | HEM A 501 ( 3.6A)HEM A 501 (-3.4A)HEM A 501 (-2.7A) | 0.43A | 3e4eB-6bldA:30.7 | 3e4eB-6bldA:9.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6c93 | CYTOCHROME P450 4B1 (Oryctolaguscuniculus) |
no annotation | 3 | ALA A 310THR A 314CYH A 448 | HEM A 600 ( 3.2A)HEM A 600 ( 3.7A)HEM A 600 (-2.1A) | 0.31A | 3e4eB-6c93A:33.2 | 3e4eB-6c93A:10.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gii | CYTOCHROME P450 (Tepidiphilusthermophilus) |
no annotation | 3 | ALA A 308THR A 312CYH A 419 | HEM A 501 (-3.7A)HEM A 501 (-3.7A)HEM A 501 (-2.4A) | 0.44A | 3e4eB-6giiA:29.6 | 3e4eB-6giiA:8.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gk6 | - (-) |
no annotation | 3 | ALA A 243THR A 247CYH A 354 | HEM A 501 ( 3.5A)HEM A 501 ( 3.4A)HEM A 501 (-2.3A) | 0.22A | 3e4eB-6gk6A:31.0 | 3e4eB-6gk6A:undetectable |