SIMILAR PATTERNS OF AMINO ACIDS FOR 3E22_D_LOCD700_2

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1c3r HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN)

(Aquifex
aeolicus) 		PF00850
(Hist_deacetyl) 		5 LEU A 222
LEU A 235
ALA A 234
ALA A 274
LYS A 277
 None
 1.09A 3e22D-1c3rA:
4.5		 3e22D-1c3rA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1g65 PROTEASOME COMPONENT
PUP3

(Saccharomyces
cerevisiae) 		PF00227
(Proteasome) 		5 ALA I 158
LEU I 160
MET I 191
ALA I 173
VAL I 175
 None
 1.26A 3e22D-1g65I:
undetectable		 3e22D-1g65I:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rw9 CHONDROITIN AC LYASE

(Paenarthrobacter
aurescens) 		PF02278
(Lyase_8)
PF02884
(Lyase_8_C)
PF08124
(Lyase_8_N) 		5 LEU A 143
LEU A 136
ALA A 139
LEU A  79
ALA A 110
 None
 0.98A 3e22D-1rw9A:
undetectable		 3e22D-1rw9A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ulq PUTATIVE ACETYL-COA
ACETYLTRANSFERASE

(Thermus
thermophilus) 		PF00108
(Thiolase_N)
PF02803
(Thiolase_C) 		5 LEU A 382
LEU A 366
ALA A 383
ALA A  97
VAL A 281
 None
 1.27A 3e22D-1ulqA:
undetectable		 3e22D-1ulqA:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w25 STALKED-CELL
DIFFERENTIATION
CONTROLLING PROTEIN

(Caulobacter
vibrioides) 		PF00072
(Response_reg)
PF00990
(GGDEF) 		5 LEU A 244
ALA A 114
ASN A 249
ALA A 230
VAL A 232
 None
 1.25A 3e22D-1w25A:
4.3		 3e22D-1w25A:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xg2 PECTINESTERASE
INHIBITOR

(Actinidia
chinensis) 		PF04043
(PMEI) 		5 CYH B 139
LEU B 143
LEU B  85
ALA B 104
ALA B 111
 None
 1.29A 3e22D-1xg2B:
undetectable		 3e22D-1xg2B:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yc6 COAT PROTEIN

(Brome mosaic
virus) 		no annotation 5 LEU A 171
LEU A  73
LEU A 152
ASN A 151
VAL A  87
 None
 1.23A 3e22D-1yc6A:
undetectable		 3e22D-1yc6A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yc6 COAT PROTEIN

(Brome mosaic
virus) 		no annotation 5 LEU A 171
LEU A 152
ASN A 151
ALA A 144
VAL A  87
 None
 1.04A 3e22D-1yc6A:
undetectable		 3e22D-1yc6A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1yrw PROTEIN ARNA

(Escherichia
coli) 		PF00551
(Formyl_trans_N)
PF02911
(Formyl_trans_C) 		5 LEU A 177
ALA A  18
LEU A  20
VAL A   5
LYS A   1
 None
 1.14A 3e22D-1yrwA:
4.7		 3e22D-1yrwA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zso HYPOTHETICAL PROTEIN

(Plasmodium
falciparum) 		PF05907
(DUF866) 		5 LEU A 151
LEU A  12
ALA A  10
ASN A  89
VAL A 117
 None
 1.30A 3e22D-1zsoA:
undetectable		 3e22D-1zsoA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2c0l NONSPECIFIC
LIPID-TRANSFER
PROTEIN

(Homo sapiens) 		PF02036
(SCP2) 		5 CYH B  91
LEU B 127
ALA B 128
LEU B 131
ASN B 133
 None
 1.25A 3e22D-2c0lB:
undetectable		 3e22D-2c0lB:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cn1 CYTOSOLIC
5'-NUCLEOTIDASE III

(Homo sapiens) 		PF05822
(UMPH-1) 		5 LEU A 225
LEU A 282
ALA A 278
ASN A 137
VAL A 149
 None
 1.29A 3e22D-2cn1A:
5.3		 3e22D-2cn1A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cx7 STEROL CARRIER
PROTEIN 2

(Thermus
thermophilus) 		PF02036
(SCP2) 		5 LEU A 102
ALA A  96
LEU A  94
ALA A 119
VAL A 123
 None
 0.91A 3e22D-2cx7A:
undetectable		 3e22D-2cx7A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2exr CYTOKININ
DEHYDROGENASE 7

(Arabidopsis
thaliana) 		PF01565
(FAD_binding_4)
PF09265
(Cytokin-bind) 		5 CYH A 149
LEU A 146
LEU A 235
ALA A 156
ASN A 190
 None
 1.26A 3e22D-2exrA:
undetectable		 3e22D-2exrA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fge ZINC METALLOPROTEASE
(INSULINASE FAMILY)

(Arabidopsis
thaliana) 		PF00675
(Peptidase_M16)
PF05193
(Peptidase_M16_C)
PF08367
(M16C_assoc) 		5 CYH A 758
LEU A 783
ALA A 754
LEU A 752
VAL A 579
 None
 1.27A 3e22D-2fgeA:
undetectable		 3e22D-2fgeA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fo1 LIN-12 PROTEIN

(Caenorhabditis
elegans) 		PF00023
(Ank)
PF12796
(Ank_2) 		5 LEU E1109
LEU E1100
ALA E1061
LEU E1057
ALA E1089
 None
 1.24A 3e22D-2fo1E:
undetectable		 3e22D-2fo1E:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fo1 LIN-12 PROTEIN

(Caenorhabditis
elegans) 		PF00023
(Ank)
PF12796
(Ank_2) 		5 LEU E1113
LEU E1100
ALA E1061
LEU E1057
ALA E1089
 None
 1.28A 3e22D-2fo1E:
undetectable		 3e22D-2fo1E:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2g6b RAS-RELATED PROTEIN
RAB-26

(Homo sapiens) 		PF00071
(Ras) 		5 LEU A  80
LEU A 115
LEU A 141
MET A 173
ALA A 217
 None
 1.29A 3e22D-2g6bA:
4.0		 3e22D-2g6bA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2h2m COMM
DOMAIN-CONTAINING
PROTEIN 1

(Homo sapiens) 		PF17221
(COMMD1_N) 		6 LEU A  39
LEU A  35
ALA A  18
LEU A  15
MET A  55
VAL A  43
 None
 1.38A 3e22D-2h2mA:
undetectable		 3e22D-2h2mA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i44 SERINE-THREONINE
PHOSPHATASE 2C

(Toxoplasma
gondii) 		PF00481
(PP2C) 		5 LEU A  86
ALA A 119
LEU A 116
ALA A 153
VAL A  54
 None
 1.20A 3e22D-2i44A:
undetectable		 3e22D-2i44A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i6e HYPOTHETICAL PROTEIN

(Deinococcus
radiodurans) 		PF02621
(VitK2_biosynth) 		5 LEU A 220
LEU A  34
ASN A  63
ALA A  19
VAL A  40
 None
 1.07A 3e22D-2i6eA:
undetectable		 3e22D-2i6eA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iml HYPOTHETICAL PROTEIN

(Archaeoglobus
fulgidus) 		PF04289
(DUF447) 		5 LEU A  47
LEU A 114
ALA A  45
ASN A  13
ALA A  64
 FMN  A 200 (-4.5A)
None
None
None
None
 1.17A 3e22D-2imlA:
undetectable		 3e22D-2imlA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jii SERINE/THREONINE-PRO
TEIN KINASE VRK3
MOLECULE: VACCINIA
RELATED KINASE 3

(Homo sapiens) 		PF00069
(Pkinase) 		6 LEU A 324
LEU A 239
ALA A 293
LEU A 297
ASN A 300
ALA A 222
 None
 1.33A 3e22D-2jiiA:
undetectable		 3e22D-2jiiA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l10 TALIN-1

(Mus musculus) 		PF08913
(VBS) 		5 LEU A1249
ALA A1253
LEU A1256
ALA A1212
VAL A1216
 None
 1.26A 3e22D-2l10A:
undetectable		 3e22D-2l10A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2og9 MANDELATE
RACEMASE/MUCONATE
LACTONIZING ENZYME

(Polaromonas sp.
JS666) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		5 LEU A 204
LEU A 166
ALA A 170
VAL A 197
LYS A 184
 None
 1.22A 3e22D-2og9A:
3.0		 3e22D-2og9A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pfm ADENYLOSUCCINATE
LYASE

(Bacillus
anthracis) 		PF00206
(Lyase_1)
PF10397
(ADSL_C) 		5 LEU A 228
ALA A 318
ASN A 323
MET A  10
ALA A 111
 None
 1.19A 3e22D-2pfmA:
undetectable		 3e22D-2pfmA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2r7d RIBONUCLEASE II
FAMILY PROTEIN

(Deinococcus
radiodurans) 		PF00773
(RNB) 		5 CYH A 269
LEU A 272
ALA A 223
LEU A 222
VAL A 104
 None
 1.21A 3e22D-2r7dA:
undetectable		 3e22D-2r7dA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uz0 TRIBUTYRIN ESTERASE

(Streptococcus
pneumoniae) 		PF00756
(Esterase) 		5 LEU A 146
ALA A 211
LYS A 213
LEU A 215
ALA A 185
 None
 1.26A 3e22D-2uz0A:
3.3		 3e22D-2uz0A:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2va8 SKI2-TYPE HELICASE

(Sulfolobus
solfataricus) 		PF00270
(DEAD)
PF00271
(Helicase_C) 		5 LEU A  44
ALA A  31
LYS A  34
ASN A  40
VAL A 143
 None
 1.24A 3e22D-2va8A:
undetectable		 3e22D-2va8A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2voy POTENTIAL
COPPER-TRANSPORTING
ATPASE

(Bacillus
subtilis) 		PF00403
(HMA) 		5 LEU A  64
LEU A  57
ALA A  60
ALA A  34
VAL A  43
 None
 1.18A 3e22D-2voyA:
undetectable		 3e22D-2voyA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x5r HYPOTHETICAL PROTEIN
ORF126

(Pyrobaculum
spherical virus) 		no annotation 5 LEU A  61
ALA A  65
ASN A 100
ALA A  97
VAL A  41
 None
 1.09A 3e22D-2x5rA:
undetectable		 3e22D-2x5rA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b2r CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		5 CYH A 596
LEU A 600
ALA A 572
LEU A 569
ALA A 546
 None
 1.06A 3e22D-3b2rA:
undetectable		 3e22D-3b2rA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b64 MACROPHAGE MIGRATION
INHIBITORY
FACTOR-LIKE PROTEIN

(Leishmania
major) 		PF01187
(MIF) 		5 LEU A  19
ALA A  83
LYS A  86
ALA A  58
VAL A  60
 None
 1.10A 3e22D-3b64A:
undetectable		 3e22D-3b64A:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bh1 UPF0371 PROTEIN
DIP2346

(Corynebacterium
diphtheriae) 		PF08903
(DUF1846) 		5 LEU A 436
ALA A 440
ASN A 445
ALA A 395
LYS A 392
 None
None
None
None
GOL  A 507 (-3.0A)
 1.21A 3e22D-3bh1A:
undetectable		 3e22D-3bh1A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjc CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE

(Homo sapiens) 		PF00233
(PDEase_I) 		5 CYH A 596
LEU A 600
ALA A 572
LEU A 569
ALA A 546
 None
 1.06A 3e22D-3bjcA:
undetectable		 3e22D-3bjcA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bjz PHOSPHOHEPTOSE
ISOMERASE

(Pseudomonas
aeruginosa) 		PF13580
(SIS_2) 		5 LEU A  25
LEU A 184
ALA A 180
ALA A 143
VAL A 161
 None
 1.28A 3e22D-3bjzA:
4.3		 3e22D-3bjzA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3brs PERIPLASMIC BINDING
PROTEIN/LACI
TRANSCRIPTIONAL
REGULATOR

(Lachnoclostridium
phytofermentans) 		PF13407
(Peripla_BP_4) 		5 LEU A 153
LYS A 125
ASN A 126
ALA A 240
VAL A 242
 None
 1.20A 3e22D-3brsA:
2.9		 3e22D-3brsA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d3j ENHANCER OF
MRNA-DECAPPING
PROTEIN 3

(Homo sapiens) 		PF03853
(YjeF_N)
PF09532
(FDF) 		5 LEU A 406
LEU A 317
ALA A 316
ALA A 358
VAL A 362
 None
 1.29A 3e22D-3d3jA:
2.7		 3e22D-3d3jA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ddn D-3-PHOSPHOGLYCERATE
DEHYDROGENASE

(Mycobacterium
tuberculosis) 		PF00389
(2-Hacid_dh)
PF01842
(ACT)
PF02826
(2-Hacid_dh_C) 		5 LEU A  49
LEU A  67
ALA A  47
LEU A   8
VAL A  56
 None
 1.20A 3e22D-3ddnA:
undetectable		 3e22D-3ddnA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dfa CALCIUM-DEPENDENT
PROTEIN KINASE
CGD3_920

(Cryptosporidium
parvum) 		PF00069
(Pkinase) 		5 CYH A 257
LEU A 258
LEU A 239
ALA A 191
VAL A 188
 None
 1.18A 3e22D-3dfaA:
undetectable		 3e22D-3dfaA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fij LIN1909 PROTEIN

(Listeria
innocua) 		PF07722
(Peptidase_C26) 		5 LEU A  65
LEU A 105
ALA A 104
ALA A 124
VAL A 121
 None
 1.10A 3e22D-3fijA:
undetectable		 3e22D-3fijA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fvr ACETYL XYLAN
ESTERASE

(Bacillus
pumilus) 		PF05448
(AXE1) 		5 LEU A 284
ALA A 254
LEU A 250
ALA A 202
VAL A 200
 None
 0.94A 3e22D-3fvrA:
3.4		 3e22D-3fvrA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h1g CHEMOTAXIS PROTEIN
CHEY HOMOLOG

(Helicobacter
pylori) 		PF00072
(Response_reg) 		5 LEU A  64
ALA A  37
LYS A  40
LEU A  41
ASN A  44
 None
 1.23A 3e22D-3h1gA:
5.4		 3e22D-3h1gA:
15.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3j23 CAPSID PROTEIN VP3

(Enterovirus A) 		PF00073
(Rhv) 		5 LEU C  53
ALA C 216
ASN C  56
ALA C  84
VAL C 194
 None
 1.29A 3e22D-3j23C:
undetectable		 3e22D-3j23C:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jzd IRON-CONTAINING
ALCOHOL
DEHYDROGENASE

(Cupriavidus
pinatubonensis) 		PF00465
(Fe-ADH) 		6 CYH A 222
LEU A 223
LEU A 202
ALA A 226
ASN A 173
VAL A 209
 None
None
None
None
NAD  A 400 ( 4.8A)
None
 1.41A 3e22D-3jzdA:
2.9		 3e22D-3jzdA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k1z HALOACID
DEHALOGENASE-LIKE
HYDROLASE
DOMAIN-CONTAINING
PROTEIN 3

(Homo sapiens) 		PF13419
(HAD_2) 		5 ALA A 240
LEU A 241
MET A   7
ALA A 188
VAL A 190
 None
 0.97A 3e22D-3k1zA:
4.0		 3e22D-3k1zA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k31 ENOYL-(ACYL-CARRIER-
PROTEIN) REDUCTASE

(Anaplasma
phagocytophilum) 		PF13561
(adh_short_C2) 		5 LEU A 235
ALA A 231
ALA A  36
VAL A  38
LYS A  10
 None
 1.23A 3e22D-3k31A:
6.7		 3e22D-3k31A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k5w CARBOHYDRATE KINASE

(Helicobacter
pylori) 		PF01256
(Carb_kinase)
PF03853
(YjeF_N) 		5 LEU A 423
LEU A 416
ALA A 437
ASN A 400
VAL A 338
 None
 1.20A 3e22D-3k5wA:
2.8		 3e22D-3k5wA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pl2 SUGAR KINASE,
RIBOKINASE FAMILY

(Corynebacterium
glutamicum) 		PF00294
(PfkB) 		5 CYH A 205
LEU A 171
ALA A 208
ALA A 229
VAL A 231
 None
 0.97A 3e22D-3pl2A:
4.8		 3e22D-3pl2A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3po0 SMALL ARCHAEAL
MODIFIER PROTEIN 1

(Haloferax
volcanii) 		PF02597
(ThiS) 		6 LEU A  60
LEU A  80
ALA A  79
LEU A  78
MET A   1
ALA A  31
 None
 1.49A 3e22D-3po0A:
undetectable		 3e22D-3po0A:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ro2 G-PROTEIN-SIGNALING
MODULATOR 2

(Mus musculus) 		PF13176
(TPR_7)
PF13424
(TPR_12) 		5 LEU A 248
LEU A 241
ALA A 244
ASN A 203
ALA A 217
 None
 1.26A 3e22D-3ro2A:
undetectable		 3e22D-3ro2A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zfx EPHRIN TYPE-B
RECEPTOR 1

(Homo sapiens) 		PF07714
(Pkinase_Tyr) 		5 ALA A 704
LEU A 751
ALA A 649
VAL A 633
LYS A 635
 None
 1.20A 3e22D-3zfxA:
undetectable		 3e22D-3zfxA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zny CTX-M-12A ENZYME

(Klebsiella
pneumoniae) 		PF13354
(Beta-lactamase2) 		5 LEU A 138
ALA A 126
LEU A 127
ASN A 214
MET A 211
 None
 1.07A 3e22D-3znyA:
undetectable		 3e22D-3znyA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxu CTF19

(Kluyveromyces
lactis) 		no annotation 5 LEU B 132
LEU B 158
MET B 154
ALA B 181
VAL B 185
 None
 1.08A 3e22D-3zxuB:
undetectable		 3e22D-3zxuB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zxu CTF19

(Kluyveromyces
lactis) 		no annotation 5 LEU B 133
LEU B 158
ALA B 140
MET B 154
ALA B 172
 None
 1.27A 3e22D-3zxuB:
undetectable		 3e22D-3zxuB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4amg SNOGD

(Streptomyces
nogalater) 		PF06722
(DUF1205) 		5 LEU A 217
LEU A 291
ALA A 290
ASN A 212
VAL A 283
 None
 1.18A 3e22D-4amgA:
4.9		 3e22D-4amgA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bg5 BBA65

(Borreliella
burgdorferi) 		PF05714
(Borrelia_lipo_1) 		5 LEU A 224
ALA A 136
LEU A 140
ASN A 143
MET A 144
 None
 1.06A 3e22D-4bg5A:
undetectable		 3e22D-4bg5A:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4e1j GLYCEROL KINASE

(Sinorhizobium
meliloti) 		PF00370
(FGGY_N)
PF02782
(FGGY_C) 		5 LEU A 182
ALA A 173
LEU A 166
ASN A 169
VAL A 231
 None
 1.29A 3e22D-4e1jA:
undetectable		 3e22D-4e1jA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fid G PROTEIN ALPHA
SUBUNIT

(Entamoeba
histolytica) 		PF00503
(G-alpha) 		5 LEU A 250
ALA A 340
ASN A 347
MET A 348
VAL A  26
 None
 1.28A 3e22D-4fidA:
2.0		 3e22D-4fidA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gr4 NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
lydicus) 		PF00501
(AMP-binding)
PF03621
(MbtH) 		5 LEU A 350
ALA A 328
LEU A 304
ALA A 321
VAL A 315
 None
 1.26A 3e22D-4gr4A:
undetectable		 3e22D-4gr4A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gr5 NON-RIBOSOMAL
PEPTIDE SYNTHETASE

(Streptomyces
lydicus) 		PF00501
(AMP-binding)
PF03621
(MbtH) 		5 LEU A 350
ALA A 328
LEU A 304
ALA A 321
VAL A 315
 None
 1.26A 3e22D-4gr5A:
undetectable		 3e22D-4gr5A:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k7g 3-HYDROXYPROLINE
DEHYDRATSE

(Agrobacterium
vitis) 		PF05544
(Pro_racemase) 		5 CYH B 225
ALA B 245
LEU B 194
ALA B 179
VAL B 177
 None
None
None
None
CIT  B 901 (-4.1A)
 1.06A 3e22D-4k7gB:
undetectable		 3e22D-4k7gB:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k8l PROLINE RACEMASE

(Ochrobactrum
anthropi) 		PF05544
(Pro_racemase) 		5 CYH A 224
ALA A 244
LEU A 194
ALA A 179
VAL A 177
 None
 1.14A 3e22D-4k8lA:
undetectable		 3e22D-4k8lA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7m PUTATIVE
UNCHARACTERIZED
PROTEIN

(Thermococcus
onnurineus) 		PF13646
(HEAT_2) 		5 LEU A  41
LEU A  57
ALA A  53
ALA A  83
VAL A  79
 None
 1.18A 3e22D-4l7mA:
undetectable		 3e22D-4l7mA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p72 PHENYLALANINE--TRNA
LIGASE BETA SUBUNIT

(Pseudomonas
aeruginosa) 		PF01588
(tRNA_bind)
PF03147
(FDX-ACB)
PF03483
(B3_4)
PF03484
(B5) 		5 LEU A 666
LEU A 641
ALA A 640
ALA A 592
VAL A 676
 None
 1.22A 3e22D-4p72A:
undetectable		 3e22D-4p72A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4q6x PHOSPHOLIPASE D
STSICTOX-BETAIC1

(Sicarius
terrosus) 		no annotation 5 LEU A 131
LEU A  94
ASN A 104
ALA A  42
VAL A  34
 None
 1.24A 3e22D-4q6xA:
undetectable		 3e22D-4q6xA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qr8 XAA-PRO DIPEPTIDASE

(Escherichia
coli) 		PF00557
(Peptidase_M24) 		5 LEU A 244
LEU A 220
ALA A 219
ASN A 198
ALA A 184
 None
 1.28A 3e22D-4qr8A:
undetectable		 3e22D-4qr8A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rtf CHAPERONE PROTEIN
DNAK

(Mycobacterium
tuberculosis) 		PF00012
(HSP70) 		5 LEU D 224
LEU D 255
ASN D 254
ALA D 237
VAL D 209
 None
 1.18A 3e22D-4rtfD:
undetectable		 3e22D-4rtfD:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rzi 3-KETOACYL-ACYL
CARRIER PROTEIN
REDUCTASE

(Synechocystis
sp. PCC 6803) 		no annotation 5 LEU B  27
LEU B 219
ALA B 216
VAL B  35
LYS B   9
 None
 1.07A 3e22D-4rziB:
6.4		 3e22D-4rziB:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase) 		5 LEU A 386
ALA A 434
LEU A 438
ALA A 318
LYS A 319
 None
 1.19A 3e22D-4u3tA:
undetectable		 3e22D-4u3tA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u9i PERIPLASMIC [NIFE]
HYDROGENASE SMALL
SUBUNIT

(Desulfovibrio
vulgaris) 		PF01058
(Oxidored_q6)
PF14720
(NiFe_hyd_SSU_C) 		5 CYH S  98
LEU S  95
LEU S 102
ASN S 134
ALA S 115
 None
None
None
MPD  S2004 (-4.0A)
None
 1.05A 3e22D-4u9iS:
3.7		 3e22D-4u9iS:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4v12 MAOC LIKE DOMAIN
PROTEIN

(Mycolicibacterium
smegmatis) 		PF01575
(MaoC_dehydratas)
PF13452
(MaoC_dehydrat_N) 		5 LEU A 242
ALA A 249
LYS A 250
ALA A 161
VAL A 165
 None
 1.24A 3e22D-4v12A:
undetectable		 3e22D-4v12A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xdt FAD:PROTEIN FMN
TRANSFERASE

(Treponema
pallidum) 		PF02424
(ApbE) 		5 LEU A 175
LEU A  38
ALA A  37
ALA A 184
VAL A 186
 None
 1.21A 3e22D-4xdtA:
undetectable		 3e22D-4xdtA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xg0 UNCHARACTERIZED
PROTEIN

(Bordetella
bronchiseptica) 		PF07005
(DUF1537)
PF17042
(DUF1357_C) 		5 LEU A 326
LEU A 368
ALA A 373
ALA A 346
VAL A 344
 None
 1.28A 3e22D-4xg0A:
undetectable		 3e22D-4xg0A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xsr ALR3699 PROTEIN

(Nostoc sp. PCC
7120) 		no annotation 5 CYH B 225
ALA B 221
LEU B 218
ALA B 231
VAL B 229
 None
 1.26A 3e22D-4xsrB:
5.4		 3e22D-4xsrB:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4z1p CELL WALL SURFACE
ANCHOR PROTEIN

(Streptococcus
agalactiae) 		PF16364
(Antigen_C) 		5 LEU A  59
ALA A  58
LEU A 170
ASN A 168
ALA A  22
 None
 1.20A 3e22D-4z1pA:
undetectable		 3e22D-4z1pA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zz7 METHYLMALONATE-SEMIA
LDEHYDE
DEHYDROGENASE

(Oceanimonas
doudoroffii) 		PF00171
(Aldedh) 		5 LEU A  74
ALA A 191
LEU A 188
MET A 198
VAL A 108
 None
 1.10A 3e22D-4zz7A:
undetectable		 3e22D-4zz7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5a51 AT3G17980

(Arabidopsis
thaliana) 		PF00168
(C2) 		5 LEU A 171
ALA A 115
LEU A  98
ALA A 181
VAL A 168
 None
 1.23A 3e22D-5a51A:
undetectable		 3e22D-5a51A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cdh MAJOR ACID
PHOSPHATASE

(Legionella
pneumophila) 		PF00328
(His_Phos_2) 		5 LEU A  54
LEU A  43
ALA A  42
ALA A 215
VAL A 209
 None
 1.25A 3e22D-5cdhA:
undetectable		 3e22D-5cdhA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eso 2-SUCCINYL-5-ENOLPYR
UVYL-6-HYDROXY-3-CYC
LOHEXENE-1-CARBOXYLA
TE SYNTHASE

(Mycobacterium
tuberculosis) 		PF02776
(TPP_enzyme_N) 		5 LEU A  25
LEU A 103
ALA A  76
ALA A   8
VAL A  12
 None
 0.94A 3e22D-5esoA:
undetectable		 3e22D-5esoA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5f5v PRP38
ZINC FINGER
DOMAIN-CONTAINING
PROTEIN

(Chaetomium
thermophilum) 		PF03371
(PRP38)
no annotation 		5 LEU A 102
LEU A 116
ALA A 120
LEU A  92
VAL C 141
 None
 1.24A 3e22D-5f5vA:
undetectable		 3e22D-5f5vA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5g4l OXIDOREDUCTASE,
SHORT CHAIN
DEHYDROGENASE/REDUCT
ASE FAMILY PROTEIN

(Clostridium sp.) 		PF13561
(adh_short_C2) 		5 LEU A  33
LEU A 240
ALA A  42
VAL A  44
LYS A  18
 None
 1.19A 3e22D-5g4lA:
6.8		 3e22D-5g4lA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h6o PORPHOBILINOGEN
DEAMINASE

(Vibrio cholerae) 		no annotation 5 LEU A 244
ASN A 241
MET A 240
ALA A 267
VAL A 278
 None
 1.07A 3e22D-5h6oA:
undetectable		 3e22D-5h6oA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksh PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		5 LEU A 386
ALA A 434
LEU A 438
ALA A 318
LYS A 319
 None
 1.21A 3e22D-5kshA:
undetectable		 3e22D-5kshA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mg5 HYDROXYMETHYLGLUTARY
L-COA SYNTHASE

(Pseudomonas
protegens) 		no annotation 5 LEU A 332
LEU A 282
ALA A  13
ALA A 161
VAL A 272
 None
 1.06A 3e22D-5mg5A:
undetectable		 3e22D-5mg5A:
14.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mpt CITRININ POLYKETIDE
SYNTHASE

(Monascus
purpureus) 		PF08242
(Methyltransf_12) 		5 LEU A2089
ALA A2062
LEU A2061
MET A2002
ALA A1968
 None
 1.17A 3e22D-5mptA:
3.1		 3e22D-5mptA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5msc CARBOXYLIC ACID
REDUCTASE

(Nocardia
iowensis) 		PF00501
(AMP-binding) 		5 CYH A 179
LEU A 158
LEU A 121
ALA A 149
VAL A 151
 None
 1.26A 3e22D-5mscA:
2.2		 3e22D-5mscA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mu3 CENTRAL KINETOCHORE
SUBUNIT CTF19

(Kluyveromyces
lactis) 		no annotation 5 LEU E 133
LEU E 158
ALA E 140
MET E 154
ALA E 172
 None
 1.23A 3e22D-5mu3E:
undetectable		 3e22D-5mu3E:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5nji PHTHIOCEROL/PHENOLPH
THIOCEROL SYNTHESIS
POLYKETIDE SYNTHASE
TYPE I PPSC

(Mycobacterium
tuberculosis) 		PF14765
(PS-DH) 		5 LEU A1198
LEU A1132
ALA A1131
ALA A 973
VAL A1169
 None
8Z2  A1301 ( 3.8A)
None
None
None
 1.12A 3e22D-5njiA:
undetectable		 3e22D-5njiA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5npu ANC27

(synthetic
construct) 		no annotation 5 LEU A   9
ALA A  10
LEU A  42
ALA A  68
VAL A  70
 None
 1.16A 3e22D-5npuA:
undetectable		 3e22D-5npuA:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5upr TRIOSEPHOSPHATE
ISOMERASE

(Toxoplasma
gondii) 		PF00121
(TIM) 		5 LEU A 210
LEU A 238
ALA A 237
ALA A 274
VAL A 271
 None
 1.14A 3e22D-5uprA:
undetectable		 3e22D-5uprA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wlh LBACAS13A H328A
(C2C2)

(Lachnospiraceae
bacterium
NK4A179) 		no annotation 5 LEU A 200
ALA A 203
LYS A 163
ASN A 160
VAL A 215
 None
 1.20A 3e22D-5wlhA:
undetectable		 3e22D-5wlhA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x6x MRNA CAPPING ENZYME
P5

(Rice dwarf
virus) 		no annotation 5 LEU C 473
LEU C 477
LEU C 503
ASN C 507
VAL C 483
 None
 1.21A 3e22D-5x6xC:
undetectable		 3e22D-5x6xC:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5x7n DIAMINOPIMELATE
DECARBOXYLASE

(Corynebacterium
glutamicum) 		no annotation 5 LEU A  93
LEU A 105
ALA A 104
ASN A  99
VAL A 134
 None
 1.02A 3e22D-5x7nA:
undetectable		 3e22D-5x7nA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6bf6 INSULIN-DEGRADING
ENZYME

(Homo sapiens) 		no annotation 5 LEU A 642
LEU A 616
LEU A 574
ASN A 573
LYS A 571
 None
 1.17A 3e22D-6bf6A:
undetectable		 3e22D-6bf6A:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c4n PSEUDOPALINE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		no annotation 5 CYH A  95
LEU A  94
LEU A  13
LEU A 120
VAL A  19
 None
None
None
None
NAP  A 501 (-3.7A)
 1.20A 3e22D-6c4nA:
2.4		 3e22D-6c4nA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c9e CYSTEINE DESULFURASE

(Legionella
pneumophila) 		no annotation 5 LYS A 168
LEU A 169
ASN A 170
ALA A 203
VAL A 205
 None
 1.06A 3e22D-6c9eA:
undetectable		 3e22D-6c9eA:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6c9m N-ALPHA-ACETYLTRANSF
ERASE 10
N-ALPHA-ACETYLTRANSF
ERASE 15, NATA
AUXILIARY SUBUNIT

(Homo sapiens) 		no annotation 5 LEU A 541
LEU B  11
ASN B  13
MET B  14
ALA B   6
 None
 1.03A 3e22D-6c9mA:
undetectable		 3e22D-6c9mA:
10.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cqb CHALCONE SYNTHASE

(Piper
methysticum) 		no annotation 5 CYH A 191
LEU A 344
ALA A 222
ALA A 175
VAL A 171
 None
 1.26A 3e22D-6cqbA:
undetectable		 3e22D-6cqbA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6e29 -

(-) 		no annotation 5 LEU D  92
LEU D  95
ASN D  33
ALA D  40
VAL D  48
 None
 1.09A 3e22D-6e29D:
undetectable		 3e22D-6e29D:
undetectable