SIMILAR PATTERNS OF AMINO ACIDS FOR 3DZY_D_BRLD478_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bsh | PROTEIN (EPSILONSUBUNIT) (Escherichiacoli) |
PF00401(ATP-synt_DE)PF02823(ATP-synt_DE_N) | 4 | ILE A 50GLN A 127ILE A 45LEU A 128 | None | 1.21A | 3dzyD-1bshA:undetectable | 3dzyD-1bshA:16.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1c7t | BETA-N-ACETYLHEXOSAMINIDASE (Serratiamarcescens) |
PF00728(Glyco_hydro_20)PF02838(Glyco_hydro_20b)PF03173(CHB_HEX)PF03174(CHB_HEX_C) | 4 | ILE A 441GLN A 363ILE A 432LEU A 756 | None | 1.33A | 3dzyD-1c7tA:0.0 | 3dzyD-1c7tA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e9y | UREASE SUBUNIT BETA (Helicobacterpylori) |
PF00449(Urease_alpha)PF01979(Amidohydro_1) | 4 | ILE B 220GLN B 244ILE B 172LEU B 296 | KCX B 219 ( 3.8A)NoneKCX B 219 ( 4.4A)None | 0.98A | 3dzyD-1e9yB:0.0 | 3dzyD-1e9yB:23.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1huj | INORGANICPYROPHOSPHATASE (Saccharomycescerevisiae) |
PF00719(Pyrophosphatase) | 4 | ILE A 19GLN A 98ILE A 68LEU A 247 | None | 1.18A | 3dzyD-1hujA:undetectable | 3dzyD-1hujA:21.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1n5x | XANTHINEDEHYDROGENASE (Bos taurus) |
PF00111(Fer2)PF00941(FAD_binding_5)PF01315(Ald_Xan_dh_C)PF01799(Fer2_2)PF02738(Ald_Xan_dh_C2)PF03450(CO_deh_flav_C) | 4 | ILE A1253GLN A1095ILE A1085LEU A1054 | None | 1.34A | 3dzyD-1n5xA:0.0 | 3dzyD-1n5xA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nvp | TRANSCRIPTIONINITIATION FACTORIIA BETA CHAINTRANSCRIPTIONINITIATION FACTORIIA GAMMA CHAIN (Homo sapiens) |
PF02268(TFIIA_gamma_N)PF02751(TFIIA_gamma_C)PF03153(TFIIA) | 4 | ILE D 44GLN D 4ILE C 357LEU D 34 | None | 1.22A | 3dzyD-1nvpD:undetectable | 3dzyD-1nvpD:12.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1pv9 | XAA-PRO DIPEPTIDASE (Pyrococcusfuriosus) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 4 | ILE A 221GLN A 245ILE A 208LEU A 282 | None | 1.15A | 3dzyD-1pv9A:0.2 | 3dzyD-1pv9A:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qls | S100C PROTEIN (Sus scrofa) |
PF00036(EF-hand_1)PF01023(S_100) | 4 | ILE A 82GLN A 76ILE A 18LEU A 67 | None | 1.19A | 3dzyD-1qlsA:undetectable | 3dzyD-1qlsA:15.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u1h | 5-METHYLTETRAHYDROPTEROYLTRIGLUTAMATE--HOMOCYSTEINEMETHYLTRANSFERASE (Arabidopsisthaliana) |
PF01717(Meth_synt_2)PF08267(Meth_synt_1) | 4 | ILE A 693GLN A 643ILE A 670LEU A 429 | None | 1.31A | 3dzyD-1u1hA:undetectable | 3dzyD-1u1hA:18.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u83 | PHOSPHOSULFOLACTATESYNTHASE (Bacillussubtilis) |
PF02679(ComA) | 4 | ILE A 22GLN A 214ILE A 168LEU A 241 | NonePO4 A1001 ( 4.6A)NoneNone | 1.07A | 3dzyD-1u83A:undetectable | 3dzyD-1u83A:21.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1w85 | PYRUVATEDEHYDROGENASE E1COMPONENT, ALPHASUBUNITPYRUVATEDEHYDROGENASE E1COMPONENT, BETASUBUNIT (Geobacillusstearothermophilus) |
PF00676(E1_dh)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | ILE B 93GLN A 150ILE B 80LEU B 71 | None | 1.17A | 3dzyD-1w85B:0.0 | 3dzyD-1w85B:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wy2 | XAA-PRO DIPEPTIDASE (Pyrococcushorikoshii) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 4 | ILE A 224GLN A 248ILE A 211LEU A 285 | None | 1.14A | 3dzyD-1wy2A:0.0 | 3dzyD-1wy2A:22.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xsz | GUANINE NUCLEOTIDEEXCHANGE PROTEIN (Legionellapneumophila) |
PF01369(Sec7) | 4 | ILE A 262GLN A 105ILE A 296LEU A 252 | None | 1.16A | 3dzyD-1xszA:undetectable | 3dzyD-1xszA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ybi | NON-TOXINHAEMAGGLUTININ HA34 (Clostridiumbotulinum) |
PF05588(Botulinum_HA-17)PF14200(RicinB_lectin_2) | 4 | ILE A 61GLN A 30ILE A 51LEU A 45 | None | 1.31A | 3dzyD-1ybiA:undetectable | 3dzyD-1ybiA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1yv9 | HYDROLASE, HALOACIDDEHALOGENASE FAMILY (Enterococcusfaecalis) |
PF13242(Hydrolase_like)PF13344(Hydrolase_6) | 4 | ILE A 204GLN A 6ILE A 10LEU A 3 | None | 1.15A | 3dzyD-1yv9A:undetectable | 3dzyD-1yv9A:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2be1 | SERINE/THREONINE-PROTEINKINASE/ENDORIBONUCLEASE IRE1 (Saccharomycescerevisiae) |
no annotation | 4 | ILE A 124GLN A 306ILE A 236LEU A 313 | None | 1.30A | 3dzyD-2be1A:undetectable | 3dzyD-2be1A:22.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfm | THERMOSTABLE DNALIGASE (Pyrococcusfuriosus) |
PF01068(DNA_ligase_A_M)PF04675(DNA_ligase_A_N)PF04679(DNA_ligase_A_C) | 4 | ILE A 264GLN A 256ILE A 371LEU A 271 | None | 1.13A | 3dzyD-2cfmA:undetectable | 3dzyD-2cfmA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cja | SERYL-TRNASYNTHETASE (Methanosarcinabarkeri) |
no annotation | 4 | ILE A 24GLN A 80ILE A 91LEU A 36 | None | 1.09A | 3dzyD-2cjaA:undetectable | 3dzyD-2cjaA:22.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2crv | TRANSLATIONINITIATION FACTORIF-2 (Mus musculus) |
no annotation | 4 | ILE A 97GLN A 36ILE A 10LEU A 16 | None | 1.11A | 3dzyD-2crvA:undetectable | 3dzyD-2crvA:15.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ekm | HYPOTHETICAL PROTEINST1511 (Sulfurisphaeratokodaii) |
PF04008(Adenosine_kin) | 4 | ILE A 47GLN A 72ILE A 88LEU A 76 | None | 1.21A | 3dzyD-2ekmA:undetectable | 3dzyD-2ekmA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gqf | HYPOTHETICAL PROTEINHI0933 (Haemophilusinfluenzae) |
PF03486(HI0933_like) | 4 | ILE A 220GLN A 246ILE A 239LEU A 99 | None | 1.23A | 3dzyD-2gqfA:undetectable | 3dzyD-2gqfA:18.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2id0 | EXORIBONUCLEASE 2 (Escherichiacoli) |
PF00575(S1)PF00773(RNB)PF08206(OB_RNB) | 4 | ILE A 477GLN A 530ILE A 506LEU A 537 | None | 1.23A | 3dzyD-2id0A:undetectable | 3dzyD-2id0A:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pfv | EXOCYST COMPLEXCOMPONENT EXO70 (Saccharomycescerevisiae) |
PF03081(Exo70) | 4 | ILE A 472GLN A 470ILE A 362LEU A 577 | None | 1.15A | 3dzyD-2pfvA:undetectable | 3dzyD-2pfvA:22.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pmz | DNA-DIRECTED RNAPOLYMERASE SUBUNITA' (Sulfolobussolfataricus) |
PF04998(RNA_pol_Rpb1_5) | 4 | ILE C 297GLN C 304ILE C 310LEU C 102 | None | 1.31A | 3dzyD-2pmzC:undetectable | 3dzyD-2pmzC:23.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qk7 | GAMMA-HEMOLYSINCOMPONENT A (Staphylococcusaureus) |
PF07968(Leukocidin) | 4 | ILE A 135GLN A 139ILE A 123LEU A 200 | None | 1.16A | 3dzyD-2qk7A:undetectable | 3dzyD-2qk7A:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uv8 | FATTY ACID SYNTHASESUBUNIT BETA (FAS1) (Saccharomycescerevisiae) |
PF00698(Acyl_transf_1)PF01575(MaoC_dehydratas)PF08354(DUF1729)PF13452(MaoC_dehydrat_N)PF16073(SAT) | 4 | ILE G 728GLN G 731ILE G 717LEU G 593 | None | 1.35A | 3dzyD-2uv8G:0.0 | 3dzyD-2uv8G:11.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vsa | MOSQUITOCIDAL TOXIN (Lysinibacillussphaericus) |
PF05588(Botulinum_HA-17)PF14200(RicinB_lectin_2) | 4 | ILE A 437GLN A 298ILE A 351LEU A 294 | None | 1.30A | 3dzyD-2vsaA:undetectable | 3dzyD-2vsaA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vxr | BOTULINUM NEUROTOXINTYPE G (Clostridiumbotulinum) |
PF07951(Toxin_R_bind_C)PF07953(Toxin_R_bind_N) | 4 | ILE A1245GLN A1114ILE A1118LEU A1280 | None | 1.35A | 3dzyD-2vxrA:undetectable | 3dzyD-2vxrA:21.72 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhg | CELLULOSE-BINDINGPROTEIN (Saccharophagusdegradans) |
PF07632(DUF1593) | 4 | ILE A 578GLN A 541ILE A 558LEU A 716 | None | 1.29A | 3dzyD-2yhgA:undetectable | 3dzyD-2yhgA:20.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ail | 303AA LONGHYPOTHETICALESTERASE (Sulfurisphaeratokodaii) |
PF07859(Abhydrolase_3) | 4 | ILE A 176GLN A 173ILE A 96LEU A 256 | None | 1.35A | 3dzyD-3ailA:undetectable | 3dzyD-3ailA:22.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3b0q | PEROXISOMEPROLIFERATOR-ACTIVATED RECEPTOR GAMMA (Homo sapiens) |
PF00104(Hormone_recep) | 4 | ILE A 281GLN A 286ILE A 341LEU A 453 | MC5 A 1 ( 4.8A)NoneMC5 A 1 (-4.5A)MC5 A 1 (-4.2A) | 0.67A | 3dzyD-3b0qA:22.5 | 3dzyD-3b0qA:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cfi | TYPE II SECRETORYPATHWAY, PSEUDOPILINEPSJ (Vibriovulnificus) |
PF11612(T2SSJ) | 4 | ILE B 58GLN B 62ILE B 89LEU B 166 | None | 1.34A | 3dzyD-3cfiB:undetectable | 3dzyD-3cfiB:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dm5 | SIGNAL RECOGNITION54 KDA PROTEIN (Pyrococcusfuriosus) |
PF00448(SRP54)PF02881(SRP54_N)PF02978(SRP_SPB) | 4 | ILE A 28GLN A 36ILE A 17LEU A 50 | None | 1.15A | 3dzyD-3dm5A:undetectable | 3dzyD-3dm5A:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dp7 | SAM-DEPENDENTMETHYLTRANSFERASE (Bacteroidesvulgatus) |
PF00891(Methyltransf_2) | 4 | ILE A 285GLN A 256ILE A 269LEU A 302 | None | 1.35A | 3dzyD-3dp7A:undetectable | 3dzyD-3dp7A:21.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fw8 | RETICULINE OXIDASE (Eschscholziacalifornica) |
PF01565(FAD_binding_4)PF08031(BBE) | 4 | ILE A 516GLN A 514ILE A 479LEU A 109 | None | 1.22A | 3dzyD-3fw8A:undetectable | 3dzyD-3fw8A:19.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hvy | CYSTATHIONINEBETA-LYASE FAMILYPROTEIN, YNBBB.SUBTILIS ORTHOLOG (Clostridiumacetobutylicum) |
PF06838(Met_gamma_lyase) | 4 | ILE A 121GLN A 182ILE A 202LEU A 129 | NoneLLP A 243 ( 4.0A)NoneNone | 1.29A | 3dzyD-3hvyA:undetectable | 3dzyD-3hvyA:22.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iay | DNA POLYMERASE DELTACATALYTIC SUBUNIT (Saccharomycescerevisiae) |
PF00136(DNA_pol_B)PF03104(DNA_pol_B_exo1) | 4 | ILE A 969GLN A 963ILE A 973LEU A 958 | None | 1.34A | 3dzyD-3iayA:undetectable | 3dzyD-3iayA:19.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3j9u | V-TYPE PROTON ATPASECATALYTIC SUBUNIT A (Saccharomycescerevisiae) |
no annotation | 4 | ILE C 353GLN C 267ILE C 254LEU C 300 | None | 1.20A | 3dzyD-3j9uC:undetectable | 3dzyD-3j9uC:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jzl | PUTATIVECYSTATHIONINEBETA-LYASE INVOLVEDIN ALUMINUMRESISTANCE (Listeriamonocytogenes) |
PF06838(Met_gamma_lyase) | 4 | ILE A 106GLN A 165ILE A 185LEU A 114 | NoneLLP A 226 ( 4.1A)NoneNone | 1.31A | 3dzyD-3jzlA:undetectable | 3dzyD-3jzlA:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k4y | ISOPENTENYLPHOSPHATE KINASE (Methanocaldococcusjannaschii) |
PF00696(AA_kinase) | 4 | ILE A 97GLN A 102ILE A 29LEU A 138 | None | 1.30A | 3dzyD-3k4yA:undetectable | 3dzyD-3k4yA:21.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kcc | CATABOLITE GENEACTIVATOR (Escherichiacoli) |
PF00027(cNMP_binding)PF00325(Crp) | 4 | ILE A 172GLN A 145ILE A 203LEU A 137 | None | 1.08A | 3dzyD-3kccA:undetectable | 3dzyD-3kccA:21.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lxq | UNCHARACTERIZEDPROTEIN VP1736 (Vibrioparahaemolyticus) |
PF00884(Sulfatase) | 4 | ILE A 527GLN A 321ILE A 498LEU A 303 | None | 1.29A | 3dzyD-3lxqA:undetectable | 3dzyD-3lxqA:20.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3m99 | UBIQUITINCARBOXYL-TERMINALHYDROLASE 8 (Saccharomycescerevisiae) |
PF00443(UCH)PF02148(zf-UBP) | 4 | ILE A 140GLN A 153ILE A 217LEU A 136 | None | 1.31A | 3dzyD-3m99A:undetectable | 3dzyD-3m99A:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n2t | PUTATIVEOXIDOREDUCTASE (Gluconobacteroxydans) |
PF00248(Aldo_ket_red) | 4 | ILE A 190GLN A 275ILE A 179LEU A 185 | None | 1.28A | 3dzyD-3n2tA:undetectable | 3dzyD-3n2tA:22.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o21 | GLUTAMATE RECEPTOR 3 (Rattusnorvegicus) |
PF01094(ANF_receptor) | 4 | ILE A 286GLN A 28ILE A 8LEU A 262 | None | 1.27A | 3dzyD-3o21A:undetectable | 3dzyD-3o21A:21.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p1w | RABGDI PROTEIN (Plasmodiumfalciparum) |
PF00996(GDI) | 4 | ILE A 124GLN A 338ILE A 347LEU A 188 | None | 1.26A | 3dzyD-3p1wA:undetectable | 3dzyD-3p1wA:23.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rc3 | ATP-DEPENDENT RNAHELICASE SUPV3L1,MITOCHONDRIAL (Homo sapiens) |
PF00271(Helicase_C)PF12513(SUV3_C) | 4 | ILE A 612GLN A 592ILE A 655LEU A 591 | None | 1.27A | 3dzyD-3rc3A:undetectable | 3dzyD-3rc3A:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3roh | LEUCOTOXIN LUKEV (Staphylococcusaureus) |
PF07968(Leukocidin) | 4 | ILE A 165GLN A 169ILE A 153LEU A 232 | None | 1.15A | 3dzyD-3rohA:undetectable | 3dzyD-3rohA:22.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rsj | BONT/F (Clostridiumbotulinum) |
PF07951(Toxin_R_bind_C)PF07953(Toxin_R_bind_N) | 4 | ILE A1023GLN A 989ILE A 977LEU A1038 | None | 1.34A | 3dzyD-3rsjA:undetectable | 3dzyD-3rsjA:20.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sqw | ATP-DEPENDENT RNAHELICASE MSS116,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | ILE A 497GLN A 502ILE A 342LEU A 485 | None | 1.01A | 3dzyD-3sqwA:undetectable | 3dzyD-3sqwA:20.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3w1s | AUTOPHAGY PROTEIN 5UBIQUITIN-LIKEPROTEIN ATG12 (Saccharomycescerevisiae) |
PF04106(APG5)PF04110(APG12) | 4 | ILE A 200GLN A 217ILE A 232LEU C 165 | None | 1.21A | 3dzyD-3w1sA:undetectable | 3dzyD-3w1sA:20.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wrc | GALLATE DIOXYGENASE (Sphingomonaspaucimobilis) |
PF02900(LigB)PF07746(LigA) | 4 | ILE A 4GLN A 47ILE A 180LEU A 273 | None | 1.33A | 3dzyD-3wrcA:undetectable | 3dzyD-3wrcA:21.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4atw | ALPHA-L-ARABINOFURANOSIDASE DOMAINPROTEIN (Thermotogamaritima) |
PF06964(Alpha-L-AF_C) | 4 | ILE A 334GLN A 326ILE A 60LEU A 293 | None | 1.21A | 3dzyD-4atwA:undetectable | 3dzyD-4atwA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bb9 | GLUCOKINASEREGULATORY PROTEIN (Homo sapiens) |
no annotation | 4 | ILE A 500GLN A 502ILE A 49LEU A 605 | None | 1.28A | 3dzyD-4bb9A:undetectable | 3dzyD-4bb9A:21.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4by6 | GENERAL NEGATIVEREGULATOR OFTRANSCRIPTIONSUBUNIT 1 (Saccharomycescerevisiae) |
PF04054(Not1) | 4 | ILE A1935GLN A1991ILE A1973LEU A1847 | None | 1.31A | 3dzyD-4by6A:undetectable | 3dzyD-4by6A:22.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4bz4 | COPPER-REPRESSIBLEPOLYPEPTIDE (Methylomicrobiumalbum) |
no annotation | 4 | ILE A 147GLN A 193ILE A 182LEU A 108 | None | 1.28A | 3dzyD-4bz4A:undetectable | 3dzyD-4bz4A:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c0t | LIKELY PROTEINKINASE (Candidaalbicans) |
PF00069(Pkinase) | 4 | ILE A 352GLN A 347ILE A 496LEU A 372 | None | 1.31A | 3dzyD-4c0tA:undetectable | 3dzyD-4c0tA:17.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c9b | PRE-MRNA-SPLICINGFACTOR CWC22 HOMOLOG (Homo sapiens) |
PF02854(MIF4G) | 4 | ILE B 170GLN B 205ILE B 181LEU B 237 | None | 1.06A | 3dzyD-4c9bB:undetectable | 3dzyD-4c9bB:20.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4d7r | PROLINE/BETAINETRANSPORTER, RALF (Legionellapneumophila;Rickettsiaprowazekii) |
PF01369(Sec7) | 4 | ILE A 260GLN A 102ILE A 294LEU A 250 | None | 1.14A | 3dzyD-4d7rA:undetectable | 3dzyD-4d7rA:23.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4db4 | ATP-DEPENDENT RNAHELICASE MSS116,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00271(Helicase_C) | 4 | ILE A 497GLN A 502ILE A 342LEU A 485 | None | 0.98A | 3dzyD-4db4A:undetectable | 3dzyD-4db4A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4db4 | ATP-DEPENDENT RNAHELICASE MSS116,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00271(Helicase_C) | 4 | ILE A 497GLN A 502ILE A 464LEU A 485 | None | 1.09A | 3dzyD-4db4A:undetectable | 3dzyD-4db4A:21.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fch | OUTER MEMBRANEPROTEIN SUSE (Bacteroidesthetaiotaomicron) |
PF16411(SusF_SusE) | 4 | ILE A 278GLN A 207ILE A 183LEU A 333 | None | 1.18A | 3dzyD-4fchA:undetectable | 3dzyD-4fchA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fem | OUTER MEMBRANEPROTEIN SUSE (Bacteroidesthetaiotaomicron) |
PF16411(SusF_SusE) | 4 | ILE A 278GLN A 207ILE A 183LEU A 333 | None | 1.17A | 3dzyD-4femA:undetectable | 3dzyD-4femA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ib2 | PUTATIVE LIPOPROTEIN ([Ruminococcus]gnavus) |
PF03180(Lipoprotein_9) | 4 | ILE A 114GLN A 92ILE A 51LEU A 108 | None | 1.23A | 3dzyD-4ib2A:undetectable | 3dzyD-4ib2A:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jx8 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] FABI (Escherichiacoli) |
PF13561(adh_short_C2) | 4 | ILE A 20GLN A 26ILE A 187LEU A 55 | NAD A 302 (-2.9A)NoneNoneNone | 1.18A | 3dzyD-4jx8A:undetectable | 3dzyD-4jx8A:21.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m87 | ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE[NADH] (Neisseriameningitidis) |
PF13561(adh_short_C2) | 4 | ILE A 24GLN A 31ILE A 223LEU A 237 | None | 1.34A | 3dzyD-4m87A:undetectable | 3dzyD-4m87A:19.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4n78 | CYTOPLASMICFMR1-INTERACTINGPROTEIN 1 (Homo sapiens) |
PF05994(FragX_IP)PF07159(DUF1394) | 4 | ILE A 507GLN A 512ILE A 592LEU A 533 | None | 1.17A | 3dzyD-4n78A:2.2 | 3dzyD-4n78A:16.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nnb | OBCA, OXALATEBIOSYNTHETICCOMPONENT A (Burkholderiaglumae) |
PF05853(BKACE) | 4 | ILE A 468GLN A 496ILE A 511LEU A 472 | None | 1.31A | 3dzyD-4nnbA:undetectable | 3dzyD-4nnbA:20.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qfh | GLUCOSE-6-PHOSPHATEISOMERASE (Trypanosomacruzi) |
PF00342(PGI) | 4 | ILE A 334GLN A 319ILE A 256LEU A 170 | None | 1.17A | 3dzyD-4qfhA:1.3 | 3dzyD-4qfhA:21.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7a | HISTONE-BINDINGPROTEIN RBBP4 (Homo sapiens) |
PF00400(WD40)PF12265(CAF1C_H4-bd) | 4 | ILE B 390GLN B 48ILE B 377LEU B 50 | None | 1.29A | 3dzyD-4r7aB:undetectable | 3dzyD-4r7aB:22.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tqk | LECTIN 2 (Agrocybeaegerita) |
PF13517(VCBS) | 4 | ILE A 188GLN A 8ILE A 124LEU A 170 | None | 1.20A | 3dzyD-4tqkA:undetectable | 3dzyD-4tqkA:19.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4tz0 | ATP-DEPENDENT RNAHELICASE MSS116,MITOCHONDRIAL (Saccharomycescerevisiae) |
PF00270(DEAD)PF00271(Helicase_C) | 4 | ILE A 497GLN A 502ILE A 342LEU A 485 | None | 1.15A | 3dzyD-4tz0A:undetectable | 3dzyD-4tz0A:23.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wt7 | ABC TRANSPORTERSUBSTRATE BINDINGPROTEIN (RIBOSE) (Agrobacteriumvitis) |
PF13407(Peripla_BP_4) | 4 | ILE A 262GLN A 247ILE A 226LEU A 276 | None | 1.34A | 3dzyD-4wt7A:undetectable | 3dzyD-4wt7A:23.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xzc | NUCLEOPROTEIN (Nairobi sheepdiseaseorthonairovirus) |
PF02477(Nairo_nucleo) | 4 | ILE A 62GLN A 438ILE A 45LEU A 444 | None | 1.17A | 3dzyD-4xzcA:0.9 | 3dzyD-4xzcA:23.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5aq1 | GLUCOSE-6-PHOSPHATEDEHYDROGENASE (Trypanosomacruzi) |
PF00479(G6PD_N)PF02781(G6PD_C) | 4 | ILE A 505GLN A 312ILE A 302LEU A 316 | None | 0.83A | 3dzyD-5aq1A:undetectable | 3dzyD-5aq1A:24.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5csu | 4-ALPHA-GLUCANOTRANSFERASE DPE1,CHLOROPLASTIC/AMYLOPLASTIC (Arabidopsisthaliana) |
PF02446(Glyco_hydro_77) | 4 | ILE A 372GLN A 122ILE A 415LEU A 124 | NoneNoneEDO A 602 ( 3.7A)None | 1.02A | 3dzyD-5csuA:undetectable | 3dzyD-5csuA:22.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fur | TRANSCRIPTIONINITIATION FACTORIIA SUBUNIT 1TRANSCRIPTIONINITIATION FACTORIIA SUBUNIT 2 (Homo sapiens) |
PF02268(TFIIA_gamma_N)PF02751(TFIIA_gamma_C)PF03153(TFIIA) | 4 | ILE D 44GLN D 4ILE C 357LEU D 34 | None | 1.22A | 3dzyD-5furD:undetectable | 3dzyD-5furD:13.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5i5l | BACTERIOPHYTOCHROMEPROTEIN (Agrobacteriumfabrum) |
PF00360(PHY)PF01590(GAF)PF08446(PAS_2) | 4 | ILE A 111GLN A 242ILE A 224LEU A 211 | None | 1.04A | 3dzyD-5i5lA:undetectable | 3dzyD-5i5lA:22.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lb3 | ATP-DEPENDENT DNAHELICASE Q5 (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF16124(RecQ_Zn_bind) | 4 | ILE B 83GLN B 63ILE B 128LEU B 93 | None | 1.12A | 3dzyD-5lb3B:undetectable | 3dzyD-5lb3B:22.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5liq | NICKING ENDONUCLEASEN.BSPD6I (Bacillus sp.(in: Bacteria)) |
PF09491(RE_AlwI) | 4 | ILE A 576GLN A 530ILE A 585LEU A 491 | None | 1.15A | 3dzyD-5liqA:undetectable | 3dzyD-5liqA:23.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lw6 | DDB_G0293866 (Dictyosteliumdiscoideum) |
no annotation | 4 | ILE A 177GLN A 161ILE A 170LEU A 17 | None | 1.27A | 3dzyD-5lw6A:undetectable | 3dzyD-5lw6A:23.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m59 | PRE-MRNA SPLICINGHELICASE-LIKEPROTEIN (Chaetomiumthermophilum) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | ILE A 586GLN A 599ILE A 612LEU A 595 | None | 1.27A | 3dzyD-5m59A:1.4 | 3dzyD-5m59A:12.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mpd | 26S PROTEASOMEREGULATORY SUBUNITRPN9 (Saccharomycescerevisiae) |
PF01399(PCI) | 4 | ILE O 291GLN O 289ILE O 270LEU O 334 | None | 1.32A | 3dzyD-5mpdO:undetectable | 3dzyD-5mpdO:24.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5myu | TYPE VI SECRETIONSYSTEM PROTEIN IMPC (Vibrio cholerae) |
PF05943(VipB) | 4 | ILE A 298GLN A 388ILE A 190LEU A 385 | None | 1.23A | 3dzyD-5myuA:undetectable | 3dzyD-5myuA:21.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mzs | FERRIC ENTEROBACTINRECEPTOR (Pseudomonasaeruginosa) |
no annotation | 4 | ILE A 146GLN A 150ILE A 38LEU A 238 | None | 1.06A | 3dzyD-5mzsA:undetectable | 3dzyD-5mzsA:10.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n9j | MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 14MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 17 (Schizosaccharomycespombe) |
PF08638(Med14)PF10156(Med17) | 4 | ILE A 184GLN A 206ILE A 167LEU W 51 | None | 1.26A | 3dzyD-5n9jA:undetectable | 3dzyD-5n9jA:22.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5n9j | MEDIATOR OF RNAPOLYMERASE IITRANSCRIPTIONSUBUNIT 17 (Schizosaccharomycespombe) |
PF10156(Med17) | 4 | ILE W 450GLN W 442ILE W 493LEU W 439 | None | 1.24A | 3dzyD-5n9jW:undetectable | 3dzyD-5n9jW:21.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nks | DIHYDROPYRIMIDINASE-RELATED PROTEIN 4 (Homo sapiens) |
no annotation | 4 | ILE A 141GLN A 196ILE A 187LEU A 105 | ILE A 141 ( 0.7A)GLN A 196 ( 0.6A)ILE A 187 ( 0.6A)LEU A 105 ( 0.6A) | 1.25A | 3dzyD-5nksA:undetectable | 3dzyD-5nksA:19.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nug | CYTOPLASMIC DYNEIN 1HEAVY CHAIN 1 (Homo sapiens) |
PF03028(Dynein_heavy)PF07728(AAA_5)PF08393(DHC_N2)PF12774(AAA_6)PF12775(AAA_7)PF12777(MT)PF12780(AAA_8)PF12781(AAA_9) | 4 | ILE A3811GLN A3709ILE A3835LEU A3802 | None | 1.24A | 3dzyD-5nugA:undetectable | 3dzyD-5nugA:6.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nx7 | PENTALENENE SYNTHASE (Streptomycesclavuligerus) |
no annotation | 4 | ILE A 302GLN A 214ILE A 268LEU A 237 | None | 1.26A | 3dzyD-5nx7A:1.9 | 3dzyD-5nx7A:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5oi9 | PUTATIVEUNCHARACTERIZEDPROTEIN (Trichoplaxadhaerens) |
no annotation | 4 | ILE A 328GLN A 49ILE A 40LEU A 123 | None | 1.32A | 3dzyD-5oi9A:undetectable | 3dzyD-5oi9A:13.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5um6 | UBIQUITIN-ACTIVATINGENZYME E1 1 (Schizosaccharomycespombe) |
PF00899(ThiF)PF09358(E1_UFD)PF10585(UBA_e1_thiolCys)PF16190(E1_FCCH)PF16191(E1_4HB) | 4 | ILE A 151GLN A 136ILE A 42LEU A 137 | None | 1.30A | 3dzyD-5um6A:0.0 | 3dzyD-5um6A:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vbn | DNA POLYMERASEEPSILON SUBUNIT 2 (Homo sapiens) |
PF04042(DNA_pol_E_B)PF12213(Dpoe2NT) | 4 | ILE A 412GLN A 406ILE A 320LEU A 275 | None | 1.34A | 3dzyD-5vbnA:undetectable | 3dzyD-5vbnA:20.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5w4b | ADENOSYLHOMOCYSTEINASE (Homo sapiens) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | ILE A 200GLN A 230ILE A 271LEU A 192 | None | 1.21A | 3dzyD-5w4bA:undetectable | 3dzyD-5w4bA:22.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wt7 | PERIOSTIN (Homo sapiens) |
no annotation | 4 | ILE A 61GLN A 68ILE A 59LEU A 29 | None | 1.24A | 3dzyD-5wt7A:undetectable | 3dzyD-5wt7A:14.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xj1 | UNCHARACTERIZED RNAMETHYLTRANSFERASESP_1029 (Streptococcuspneumoniae) |
no annotation | 4 | ILE A 226GLN A 241ILE A 236LEU A 193 | GOL A 502 (-3.9A)NoneNoneNone | 1.30A | 3dzyD-5xj1A:undetectable | 3dzyD-5xj1A:23.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xmj | FUMARATE REDUCTASEFLAVOPROTEIN SUBUNIT (Desulfovibriogigas) |
no annotation | 4 | ILE A 11GLN A 180ILE A 32LEU A 523 | FAD A 701 (-4.7A)FAD A 701 (-4.8A)NoneNone | 1.21A | 3dzyD-5xmjA:undetectable | 3dzyD-5xmjA:11.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | X-RAY REPAIRCROSS-COMPLEMENTINGPROTEIN 5 (Homo sapiens) |
PF02735(Ku)PF03730(Ku_C)PF03731(Ku_N) | 4 | ILE B 150GLN B 73ILE B 134LEU B 68 | None | 1.31A | 3dzyD-5y3rB:undetectable | 3dzyD-5y3rB:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y7f | UGGT (Thermomycesdupontii) |
PF01501(Glyco_transf_8) | 4 | ILE A1271GLN A1264ILE A1227LEU A1384 | UDP A2001 (-4.1A)NoneNoneNone | 1.31A | 3dzyD-5y7fA:undetectable | 3dzyD-5y7fA:21.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yfp | EXOCYST COMPLEXCOMPONENT EXO84 (Saccharomycescerevisiae) |
no annotation | 4 | ILE H 640GLN H 634ILE H 668LEU H 604 | None | 1.24A | 3dzyD-5yfpH:undetectable | 3dzyD-5yfpH:10.97 |