SIMILAR PATTERNS OF AMINO ACIDS FOR 3DZG_B_NCAB302_0
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1avb | ARCELIN-1 (Phaseolusvulgaris) |
PF00139(Lectin_legB) | 4 | LEU A 105ASP A 132SER A 201THR A 203 | None | 1.29A | 3dzgB-1avbA:undetectable | 3dzgB-1avbA:22.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dnp | DNA PHOTOLYASE (Escherichiacoli) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7) | 4 | ASP A 113TRP A 6SER A 83THR A 37 | None | 1.24A | 3dzgB-1dnpA:undetectable | 3dzgB-1dnpA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g8w | LEUCOAGGLUTINATINGPHYTOHEMAGGLUTININ (Phaseolusvulgaris) |
PF00139(Lectin_legB) | 4 | LEU A 108ASP A 141SER A 208THR A 210 | None | 1.38A | 3dzgB-1g8wA:undetectable | 3dzgB-1g8wA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gyc | LACCASE 2 (Trametesversicolor) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | LEU A 185GLU A 288TRP A 258SER A 276 | None | 1.37A | 3dzgB-1gycA:undetectable | 3dzgB-1gycA:18.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ism | BONE MARROW STROMALCELL ANTIGEN 1 (Homo sapiens) |
PF02267(Rib_hydrolayse) | 5 | TRP A 77LEU A 97ASP A 107TRP A 140SER A 144 | NCA A 303 (-4.4A)NCA A 303 (-4.3A)NCA A 303 (-4.4A)NCA A 303 (-4.0A)NCA A 303 ( 3.7A) | 0.49A | 3dzgB-1ismA:28.0 | 3dzgB-1ismA:34.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k7s | FERRICHROME-BINDINGPERIPLASMIC PROTEIN (Escherichiacoli) |
PF01497(Peripla_BP_2) | 4 | TRP N 273LEU N 44GLU N 42TRP N 217 | NoneNoneALB N 500 ( 3.9A)ALB N 500 (-3.7A) | 1.31A | 3dzgB-1k7sN:undetectable | 3dzgB-1k7sN:19.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l2q | MONOMETHYLAMINEMETHYLTRANSFERASE (Methanosarcinabarkeri) |
PF05369(MtmB) | 4 | LEU A 295GLU A 259SER A 365THR A 131 | XPL A 202 ( 4.8A)XPL A 202 (-2.7A)XPL A 202 ( 2.7A)XPL A 202 ( 4.5A) | 1.33A | 3dzgB-1l2qA:undetectable | 3dzgB-1l2qA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lth | L-LACTATEDEHYDROGENASE (T-AND R- STATETETRAMER COMPLEX) (Bifidobacteriumlongum) |
no annotation | 4 | LEU T 265ASP T 267SER T 263THR T 280 | None | 1.33A | 3dzgB-1lthT:2.9 | 3dzgB-1lthT:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nsv | GALACTOSE MUTAROTASE (Lactococcuslactis) |
PF01263(Aldose_epim) | 4 | LEU A 14ASP A 49SER A 16THR A 24 | None | 1.36A | 3dzgB-1nsvA:undetectable | 3dzgB-1nsvA:21.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qoz | ACETYL XYLANESTERASE (Trichodermareesei) |
PF01083(Cutinase) | 4 | GLU A 108ASP A 105SER A 60THR A 13 | None | 1.38A | 3dzgB-1qozA:2.1 | 3dzgB-1qozA:20.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qu2 | ISOLEUCYL-TRNASYNTHETASE (Staphylococcusaureus) |
PF00133(tRNA-synt_1)PF06827(zf-FPG_IleRS)PF08264(Anticodon_1) | 4 | LEU A 193GLU A 197SER A 186THR A 400 | None | 1.38A | 3dzgB-1qu2A:undetectable | 3dzgB-1qu2A:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1se9 | UBIQUITIN FAMILY (Arabidopsisthaliana) |
PF13881(Rad60-SLD_2) | 4 | LEU A 65ASP A 73SER A 60THR A 86 | None | 1.30A | 3dzgB-1se9A:undetectable | 3dzgB-1se9A:20.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1u7h | ORNITHINECYCLODEAMINASE (Pseudomonasputida) |
PF02423(OCD_Mu_crystall) | 4 | LEU A 235GLU A 258ASP A 292THR A 202 | NoneNoneNoneNAD A 802 (-4.1A) | 1.14A | 3dzgB-1u7hA:undetectable | 3dzgB-1u7hA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vkn | N-ACETYL-GAMMA-GLUTAMYL-PHOSPHATEREDUCTASE (Thermotogamaritima) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | LEU A 308GLU A 16SER A 177THR A 234 | None | 1.21A | 3dzgB-1vknA:undetectable | 3dzgB-1vknA:21.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vrq | SARCOSINE OXIDASEALPHA SUBUNIT (Corynebacteriumsp. U-96) |
PF01571(GCV_T)PF08669(GCV_T_C)PF12831(FAD_oxidored)PF13510(Fer2_4) | 4 | LEU A 700ASP A 698SER A 720THR A 722 | NoneNoneSO4 A2002 ( 4.0A)SO4 A2002 (-3.3A) | 1.36A | 3dzgB-1vrqA:undetectable | 3dzgB-1vrqA:14.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wer | P120GAP (Homo sapiens) |
PF00616(RasGAP) | 4 | LEU A 787GLU A 781ASP A 782THR A 792 | None | 1.18A | 3dzgB-1werA:undetectable | 3dzgB-1werA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b92 | INTERFERON-INDUCEDGUANYLATE-BINDINGPROTEIN 1 (Homo sapiens) |
PF02263(GBP)PF02841(GBP_C) | 4 | LEU A 67GLU A 251SER A 52THR A 75 | LEU A 67 (-0.6A)GLU A 251 ( 0.6A)SER A 52 ( 0.0A)THR A 75 ( 0.8A) | 1.32A | 3dzgB-2b92A:undetectable | 3dzgB-2b92A:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cs0 | HEMATOPOIETIC SH2DOMAIN CONTAINING (Homo sapiens) |
PF00017(SH2) | 4 | LEU A 41ASP A 27SER A 54THR A 52 | None | 1.29A | 3dzgB-2cs0A:undetectable | 3dzgB-2cs0A:18.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2d4e | 5-CARBOXYMETHYL-2-HYDROXYMUCONATESEMIALDEHYDEDEHYDROGENASE (Thermusthermophilus) |
PF00171(Aldedh) | 4 | LEU A 176GLU A 110SER A 179THR A 170 | None | 1.31A | 3dzgB-2d4eA:undetectable | 3dzgB-2d4eA:21.23 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2eg9 | ADP-RIBOSYL CYCLASE1 (Mus musculus) |
PF02267(Rib_hydrolayse) | 5 | LEU A 149GLU A 150ASP A 159TRP A 193SER A 197 | None | 0.59A | 3dzgB-2eg9A:11.1 | 3dzgB-2eg9A:54.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2eg9 | ADP-RIBOSYL CYCLASE1 (Mus musculus) |
PF02267(Rib_hydrolayse) | 6 | TRP A 129LEU A 149GLU A 150TRP A 193SER A 197THR A 225 | None | 0.88A | 3dzgB-2eg9A:11.1 | 3dzgB-2eg9A:54.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gah | HETEROTETRAMERICSARCOSINE OXIDASEALPHA-SUBUNIT (Stenotrophomonasmaltophilia) |
PF01571(GCV_T)PF07992(Pyr_redox_2)PF08669(GCV_T_C)PF13510(Fer2_4) | 4 | LEU A 701ASP A 699SER A 721THR A 723 | None | 1.39A | 3dzgB-2gahA:undetectable | 3dzgB-2gahA:12.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ip1 | TRYPTOPHANYL-TRNASYNTHETASE (Saccharomycescerevisiae) |
PF00579(tRNA-synt_1b) | 4 | GLU A 194ASP A 238SER A 291THR A 249 | None | 1.36A | 3dzgB-2ip1A:undetectable | 3dzgB-2ip1A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ivf | ETHYLBENZENEDEHYDROGENASEALPHA-SUBUNIT (Aromatoleumaromaticum) |
PF00384(Molybdopterin)PF01568(Molydop_binding) | 4 | LEU A 543TRP A 200SER A 214THR A 207 | None | 1.32A | 3dzgB-2ivfA:2.7 | 3dzgB-2ivfA:13.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lrn | THIOL:DISULFIDEINTERCHANGE PROTEIN (Bacteroides sp.4_3_47FAA) |
PF00578(AhpC-TSA) | 4 | ASP A 71TRP A 37SER A 86THR A 48 | None | 1.20A | 3dzgB-2lrnA:undetectable | 3dzgB-2lrnA:19.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2own | PUTATIVEOLEOYL-[ACYL-CARRIERPROTEIN]THIOESTERASE (Lactobacillusplantarum) |
PF01643(Acyl-ACP_TE) | 4 | LEU A 238GLU A 240ASP A 243THR A 160 | None | 1.28A | 3dzgB-2ownA:undetectable | 3dzgB-2ownA:20.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r7y | RIBONUCLEASE H (Bacillushalodurans) |
no annotation | 4 | ASP A 163TRP A 159SER A 147THR A 104 | None | 1.39A | 3dzgB-2r7yA:undetectable | 3dzgB-2r7yA:21.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uxy | ALIPHATIC AMIDASE (Pseudomonasaeruginosa) |
PF00795(CN_hydrolase) | 4 | LEU A 119ASP A 168SER A 101THR A 103 | None | 0.80A | 3dzgB-2uxyA:undetectable | 3dzgB-2uxyA:20.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhh | CG3027-PA (Drosophilamelanogaster) |
PF00795(CN_hydrolase) | 4 | LEU A 268GLU A 272SER A 265THR A 260 | None | 1.12A | 3dzgB-2vhhA:undetectable | 3dzgB-2vhhA:18.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsi | FAD SYNTHETASE (Saccharomycescerevisiae) |
PF01507(PAPS_reduct) | 4 | LEU A 131GLU A 133ASP A 108SER A 124 | None | 1.29A | 3dzgB-2wsiA:undetectable | 3dzgB-2wsiA:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2z2u | UPF0026 PROTEINMJ0257 (Methanocaldococcusjannaschii) |
PF04055(Radical_SAM)PF08608(Wyosine_form) | 4 | LEU A 268GLU A 272ASP A 271SER A 251 | None | 1.32A | 3dzgB-2z2uA:undetectable | 3dzgB-2z2uA:22.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ziu | MUS81 PROTEIN (Danio rerio) |
PF02732(ERCC4) | 4 | LEU A 341GLU A 329ASP A 361SER A 468 | None | 1.34A | 3dzgB-2ziuA:undetectable | 3dzgB-2ziuA:20.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bdq | STEROL CARRIERPROTEIN 2-LIKE 2 (Aedes aegypti) |
PF02036(SCP2) | 4 | LEU A 67GLU A 68ASP A 69SER A 2 | None | 1.28A | 3dzgB-3bdqA:undetectable | 3dzgB-3bdqA:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bgf | F26G19 FABF26G19 FAB (Mus musculus;Mus musculus) |
no annotationno annotation | 4 | TRP L 96LEU L 89TRP H 103SER L 34 | None | 1.10A | 3dzgB-3bgfL:undetectable | 3dzgB-3bgfL:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cqh | L-RIBULOSE-5-PHOSPHATE 3-EPIMERASE ULAE (Escherichiacoli) |
PF01261(AP_endonuc_2) | 4 | LEU A 189GLU A 155ASP A 120THR A 215 | None | 1.18A | 3dzgB-3cqhA:2.2 | 3dzgB-3cqhA:19.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cux | MALATE SYNTHASE (Bacillusanthracis) |
PF01274(Malate_synthase) | 4 | LEU A 245GLU A 247ASP A 275THR A 92 | MG A 1 ( 4.9A) MG A 1 (-2.6A) MG A 1 (-3.3A)None | 1.34A | 3dzgB-3cuxA:undetectable | 3dzgB-3cuxA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3cv2 | MALATE SYNTHASE A (Escherichiacoli) |
PF01274(Malate_synthase) | 4 | LEU A 248GLU A 250ASP A 278THR A 95 | OXL A1000 ( 4.7A) MG A 1 ( 2.6A) MG A 1 ( 3.1A)None | 1.26A | 3dzgB-3cv2A:2.5 | 3dzgB-3cv2A:20.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d31 | SULFATE/MOLYBDATEABC TRANSPORTER,ATP-BINDING PROTEIN (Methanosarcinaacetivorans) |
PF00005(ABC_tran)PF03459(TOBE) | 4 | LEU A 155GLU A 190ASP A 187THR A 162 | None | 1.35A | 3dzgB-3d31A:undetectable | 3dzgB-3d31A:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dgt | ENDO-1,3-BETA-GLUCANASE (Streptomycessioyaensis) |
PF00722(Glyco_hydro_16) | 4 | TRP A 137GLU A 142ASP A 144THR A 47 | None | 1.34A | 3dzgB-3dgtA:undetectable | 3dzgB-3dgtA:16.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e7g | NITRIC OXIDESYNTHASE, INDUCIBLE (Homo sapiens) |
PF02898(NO_synthase) | 4 | LEU A 125ASP A 460SER A 124THR A 109 | None | 1.33A | 3dzgB-3e7gA:undetectable | 3dzgB-3e7gA:21.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g5a | FMNADENYLYLTRANSFERASE ([Candida]glabrata) |
PF01507(PAPS_reduct) | 4 | LEU A 132GLU A 134ASP A 109SER A 125 | None | 1.25A | 3dzgB-3g5aA:undetectable | 3dzgB-3g5aA:19.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3g5a | FMNADENYLYLTRANSFERASE ([Candida]glabrata) |
PF01507(PAPS_reduct) | 4 | LEU A 132GLU A 134ASP A 109THR A 124 | None | 1.17A | 3dzgB-3g5aA:undetectable | 3dzgB-3g5aA:19.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gc6 | ECTO-NAD+GLYCOHYDROLASE (CD38MOLECULE) (Bos taurus) |
PF02267(Rib_hydrolayse) | 6 | TRP A 118LEU A 137GLU A 138ASP A 147TRP A 181SER A 185 | None | 0.55A | 3dzgB-3gc6A:30.5 | 3dzgB-3gc6A:45.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hhj | MUTATOR MUTT PROTEIN (Bartonellahenselae) |
PF14815(NUDIX_4) | 4 | LEU A 36ASP A 38TRP A 131THR A 46 | None | 1.35A | 3dzgB-3hhjA:undetectable | 3dzgB-3hhjA:22.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ht4 | ALUMINUM RESISTANCEPROTEIN (Bacillus cereus) |
PF06838(Met_gamma_lyase) | 4 | LEU A 84GLU A 71ASP A 68THR A 261 | None | 1.38A | 3dzgB-3ht4A:undetectable | 3dzgB-3ht4A:18.72 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3i9k | ADP-RIBOSYL CYCLASE (Aplysiacalifornica) |
PF02267(Rib_hydrolayse) | 5 | TRP A 77LEU A 97GLU A 98TRP A 140SER A 144 | None | 0.40A | 3dzgB-3i9kA:25.1 | 3dzgB-3i9kA:31.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ift | GLYCINE CLEAVAGESYSTEM H PROTEIN (Mycobacteriumtuberculosis) |
PF01597(GCV_H) | 4 | GLU A 80ASP A 104TRP A 101SER A 83 | None | 1.24A | 3dzgB-3iftA:undetectable | 3dzgB-3iftA:16.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3iln | LAMINARINASE (Rhodothermusmarinus) |
PF00722(Glyco_hydro_16) | 4 | TRP A 107GLU A 134ASP A 131THR A 229 | GOL A 300 (-3.4A)GOL A 300 (-3.5A)GOL A 300 (-3.6A)None | 1.36A | 3dzgB-3ilnA:undetectable | 3dzgB-3ilnA:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PRE-MRNA-SPLICINGFACTOR PRP5 (Schizosaccharomycespombe) |
PF00400(WD40) | 4 | GLU K 440ASP K 442SER K 427THR K 377 | None | 1.32A | 3dzgB-3jb9K:undetectable | 3dzgB-3jb9K:15.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k7x | LIN0763 PROTEIN (Listeriainnocua) |
PF03663(Glyco_hydro_76) | 4 | TRP A 121LEU A 124ASP A 126THR A 178 | None | 1.29A | 3dzgB-3k7xA:undetectable | 3dzgB-3k7xA:19.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3krt | CROTONYL COAREDUCTASE (Streptomycescoelicolor) |
PF00107(ADH_zinc_N)PF08240(ADH_N) | 4 | GLU A 102ASP A 115SER A 96THR A 41 | None | 0.99A | 3dzgB-3krtA:undetectable | 3dzgB-3krtA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l0g | NICOTINATE-NUCLEOTIDE PYROPHOSPHORYLASE (Ehrlichiachaffeensis) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 4 | LEU A 211ASP A 164SER A 236THR A 129 | NoneNoneEDO A 300 ( 4.6A)EDO A 300 (-4.2A) | 1.39A | 3dzgB-3l0gA:2.2 | 3dzgB-3l0gA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mzn | GLUCARATEDEHYDRATASE (Chromohalobactersalexigens) |
PF13378(MR_MLE_C) | 4 | LEU A 294ASP A 290TRP A 313THR A 284 | None | 1.35A | 3dzgB-3mznA:undetectable | 3dzgB-3mznA:20.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3oq3 | INTERFERON ALPHA-5IFN-ALPHA/BETABINDING PROTEIN C12R (Mus musculus;Ectromeliavirus) |
PF00143(Interferon)PF00047(ig)PF13895(Ig_2) | 4 | LEU A 17ASP B 259SER A 84THR A 80 | None | 1.06A | 3dzgB-3oq3A:undetectable | 3dzgB-3oq3A:22.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3p2y | ALANINEDEHYDROGENASE/PYRIDINE NUCLEOTIDETRANSHYDROGENASE (Mycolicibacteriumsmegmatis) |
PF01262(AlaDh_PNT_C)PF05222(AlaDh_PNT_N) | 4 | LEU A 308GLU A 283SER A 306THR A 291 | None | 1.27A | 3dzgB-3p2yA:3.8 | 3dzgB-3p2yA:20.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p5s | CD38 MOLECULE (Bos taurus) |
PF02267(Rib_hydrolayse) | 6 | TRP A 118LEU A 137GLU A 138ASP A 147TRP A 181SER A 185 | AVU A 280 (-3.8A)AVU A 280 (-3.7A)AVU A 280 (-3.3A)AVU A 280 (-3.9A)AVU A 280 (-3.6A)AVU A 280 (-2.9A) | 0.50A | 3dzgB-3p5sA:30.4 | 3dzgB-3p5sA:46.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q35 | VACUOLAR PROTEINSORTING-ASSOCIATEDPROTEIN 75 (Saccharomycescerevisiae) |
PF00956(NAP) | 4 | LEU B 91GLU B 94SER B 104THR B 122 | None | 1.20A | 3dzgB-3q35B:undetectable | 3dzgB-3q35B:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rip | GAMMA-TUBULINCOMPLEX COMPONENT 4 (Homo sapiens) |
PF04130(Spc97_Spc98) | 4 | LEU A 192GLU A 304ASP A 305SER A 188 | None | 1.05A | 3dzgB-3ripA:undetectable | 3dzgB-3ripA:18.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3rom | ADP-RIBOSYL CYCLASE1 (Homo sapiens) |
PF02267(Rib_hydrolayse) | 7 | TRP A 125LEU A 145GLU A 146ASP A 155TRP A 189SER A 193THR A 221 | 48Z A 301 (-3.6A)48Z A 301 ( 4.8A)48Z A 301 ( 4.3A)NoneNone48Z A 301 (-2.8A)48Z A 301 (-4.0A) | 0.45A | 3dzgB-3romA:38.8 | 3dzgB-3romA:99.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3stp | GALACTONATEDEHYDRATASE,PUTATIVE (Labrenziaaggregata) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 365ASP A 357SER A 335THR A 326 | None | 1.33A | 3dzgB-3stpA:undetectable | 3dzgB-3stpA:20.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tlm | SARCOPLASMIC/ENDOPLASMIC RETICULUMCALCIUM ATPASE 1 (Bos taurus) |
PF00122(E1-E2_ATPase)PF00689(Cation_ATPase_C)PF00690(Cation_ATPase_N)PF08282(Hydrolase_3)PF13246(Cation_ATPase) | 4 | LEU A 947ASP A 962SER A 901THR A 905 | None | 0.98A | 3dzgB-3tlmA:undetectable | 3dzgB-3tlmA:13.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tts | BETA-GALACTOSIDASE (Bacilluscirculans) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | GLU A 307ASP A 14SER A 273THR A 250 | None | 1.18A | 3dzgB-3ttsA:undetectable | 3dzgB-3ttsA:17.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u58 | TETRAHYMENA TEB1 AB (Tetrahymenathermophila) |
PF01336(tRNA_anti-codon) | 4 | LEU A 392ASP A 411TRP A 439SER A 467 | None | 1.16A | 3dzgB-3u58A:undetectable | 3dzgB-3u58A:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wz1 | AGARASE (Microbulbiferthermotolerans) |
PF00722(Glyco_hydro_16) | 4 | TRP A 138GLU A 257SER A 109THR A 111 | None | 1.22A | 3dzgB-3wz1A:undetectable | 3dzgB-3wz1A:20.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x1b | LACCASE (Lentinus) |
PF00394(Cu-oxidase)PF07731(Cu-oxidase_2)PF07732(Cu-oxidase_3) | 4 | LEU A 206GLU A 309TRP A 279SER A 297 | None | 1.30A | 3dzgB-3x1bA:undetectable | 3dzgB-3x1bA:19.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4c7v | TRANSKETOLASE (Lactobacillussalivarius) |
PF00456(Transketolase_N)PF02779(Transket_pyr)PF02780(Transketolase_C) | 4 | TRP A 587LEU A 479GLU A 613THR A 484 | None | 1.31A | 3dzgB-4c7vA:undetectable | 3dzgB-4c7vA:16.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4u | MANDALATERACEMASE/MUCONATELACTONIZING ENZYME (unidentified) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 4 | LEU A 158ASP A 355TRP A 353THR A 129 | DTU A 501 (-4.4A)NoneNoneNone | 1.08A | 3dzgB-4e4uA:2.3 | 3dzgB-4e4uA:21.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gr4 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Streptomyceslydicus) |
PF00501(AMP-binding)PF03621(MbtH) | 4 | LEU A 416ASP A 434SER A 361THR A 365 | None | 0.96A | 3dzgB-4gr4A:2.4 | 3dzgB-4gr4A:20.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4gr5 | NON-RIBOSOMALPEPTIDE SYNTHETASE (Streptomyceslydicus) |
PF00501(AMP-binding)PF03621(MbtH) | 4 | LEU A 416ASP A 434SER A 361THR A 365 | TLA A 602 (-4.6A)NoneNoneNone | 0.98A | 3dzgB-4gr5A:2.4 | 3dzgB-4gr5A:17.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hn0 | PUTATIVE 3-EPIMERASEIN D-ALLOSE PATHWAY (Streptomycesbikiniensis) |
PF00908(dTDP_sugar_isom) | 4 | LEU A 4GLU A 97SER A 11THR A 107 | None | 1.28A | 3dzgB-4hn0A:undetectable | 3dzgB-4hn0A:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i9a | QUINOLINATEPHOSPHORIBOSYLTRANSFERASE (Sus scrofa) |
PF01729(QRPTase_C)PF02749(QRPTase_N) | 5 | LEU A 220GLU A 201ASP A 172SER A 248THR A 137 | NoneNCN A 301 (-3.6A)NoneNCN A 301 (-2.9A)NCN A 301 ( 4.4A) | 1.50A | 3dzgB-4i9aA:2.2 | 3dzgB-4i9aA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4k90 | EXTRACELLULARMETALLOPROTEINASEMEP (Aspergillusfumigatus) |
PF02128(Peptidase_M36) | 4 | LEU A 449TRP A 461SER A 436THR A 432 | None | 1.09A | 3dzgB-4k90A:undetectable | 3dzgB-4k90A:17.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l1g | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
PF01522(Polysacc_deac_1) | 4 | LEU A 232ASP A 81SER A 235THR A 197 | NoneACT A 302 ( 4.0A)NoneNone | 1.11A | 3dzgB-4l1gA:undetectable | 3dzgB-4l1gA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ogz | PUTATIVEALPHA-GALACTOSIDASE/MELIBIASE (Bacteroidesfragilis) |
PF10632(He_PIG_assoc)PF16499(Melibiase_2)PF17450(Melibiase_2_C) | 4 | LEU A 119ASP A 117SER A 271THR A 50 | None | 1.35A | 3dzgB-4ogzA:2.1 | 3dzgB-4ogzA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4uzs | BETA-GALACTOSIDASE (Bifidobacteriumbifidum) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | GLU A 320ASP A 25SER A 285THR A 260 | GOL A 702 (-2.7A)NoneNoneNone | 1.19A | 3dzgB-4uzsA:undetectable | 3dzgB-4uzsA:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wxp | NS3-4 PROTEASE (Hepacivirus C) |
PF07652(Flavi_DEAD) | 4 | TRP A 582LEU A 585SER A 584THR A 550 | None | 1.12A | 3dzgB-4wxpA:2.0 | 3dzgB-4wxpA:19.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4z2q | LECTIN (Athelia rolfsii) |
PF07367(FB_lectin) | 4 | LEU A 82GLU A 86ASP A 85SER A 62 | None | 1.25A | 3dzgB-4z2qA:undetectable | 3dzgB-4z2qA:22.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5bni | UNCHARACTERIZEDPROTEIN (Sus scrofa) |
PF02267(Rib_hydrolayse) | 6 | LEU A 150GLU A 151ASP A 160TRP A 193SER A 197THR A 225 | None | 0.83A | 3dzgB-5bniA:29.5 | 3dzgB-5bniA:55.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dhd | CHITINASE (Thermococcuskodakarensis) |
PF00553(CBM_2) | 4 | GLU A 640ASP A 642TRP A 669SER A 667 | PE3 A 803 ( 4.6A)PE3 A 803 (-3.4A)NoneNone | 1.24A | 3dzgB-5dhdA:undetectable | 3dzgB-5dhdA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dl6 | PUTATIVE PORIN FORVANILLATETRAFFICKING (VANP) (Acinetobacterbaumannii) |
PF03573(OprD) | 4 | LEU A 111ASP A 56SER A 134THR A 136 | None | 1.09A | 3dzgB-5dl6A:undetectable | 3dzgB-5dl6A:20.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dlb | CHAPERONE ESPG3 (Mycobacteriummarinum) |
PF14011(ESX-1_EspG) | 4 | TRP A 83LEU A 84TRP A 283THR A 229 | None | 1.24A | 3dzgB-5dlbA:undetectable | 3dzgB-5dlbA:23.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dlq | EXPORTIN-4 (Mus musculus) |
no annotation | 4 | LEU B 651ASP B 653SER B 675THR B 672 | None | 1.28A | 3dzgB-5dlqB:undetectable | 3dzgB-5dlqB:12.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dql | ISOCITRATE LYASE 1 (Mycobacteriumtuberculosis) |
PF00463(ICL) | 4 | TRP A 283ASP A 230SER A 315THR A 347 | NoneNoneVGX A 503 (-2.5A)VGX A 503 (-3.0A) | 1.10A | 3dzgB-5dqlA:undetectable | 3dzgB-5dqlA:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dql | ISOCITRATE LYASE 1 (Mycobacteriumtuberculosis) |
PF00463(ICL) | 4 | TRP A 283GLU A 285ASP A 230SER A 315 | NoneNoneNoneVGX A 503 (-2.5A) | 1.40A | 3dzgB-5dqlA:undetectable | 3dzgB-5dqlA:17.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9a | BETA-GALACTOSIDASE (Rahnella sp. R3) |
PF02449(Glyco_hydro_42)PF08532(Glyco_hydro_42M)PF08533(Glyco_hydro_42C) | 4 | GLU A 314ASP A 19SER A 274THR A 251 | ACT A 702 (-3.3A)NoneNoneNone | 1.24A | 3dzgB-5e9aA:2.4 | 3dzgB-5e9aA:17.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9g | ISOCITRATE LYASE (Magnaportheoryzae) |
PF00463(ICL) | 4 | TRP A 403ASP A 254SER A 435THR A 467 | NoneNoneGOL A 602 (-2.6A)GOL A 602 ( 3.0A) | 1.15A | 3dzgB-5e9gA:undetectable | 3dzgB-5e9gA:19.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5e9h | ISOCITRATE LYASE (Fusariumgraminearum) |
PF00463(ICL) | 4 | TRP A 402ASP A 254SER A 434THR A 466 | NoneNoneMLI A 602 (-2.8A)MLI A 602 (-2.9A) | 1.08A | 3dzgB-5e9hA:2.4 | 3dzgB-5e9hA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f8z | PLASMA KALLIKREINLIGHT CHAIN (Homo sapiens) |
PF00089(Trypsin) | 4 | TRP A 141LEU A 71SER A 22THR A 139 | NoneSO4 A 302 (-3.0A)NoneNone | 1.32A | 3dzgB-5f8zA:undetectable | 3dzgB-5f8zA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fur | TRANSCRIPTIONINITIATION FACTORTFIID SUBUNIT 2 (Homo sapiens) |
no annotation | 4 | LEU I 667GLU I 664ASP I 400SER I 697 | None | 1.27A | 3dzgB-5furI:undetectable | 3dzgB-5furI:13.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5g | PUTATIVE XANTHINEDEHYDROGENASE YAGSFAD-BINDING SUBUNIT (Escherichiacoli) |
PF01315(Ald_Xan_dh_C)PF02738(Ald_Xan_dh_C2) | 4 | LEU C 495ASP C 464SER C 472THR C 470 | NoneNoneMCN C 921 (-4.2A)MCN C 921 (-3.8A) | 1.38A | 3dzgB-5g5gC:undetectable | 3dzgB-5g5gC:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gsl | 778AA LONGHYPOTHETICALBETA-GALACTOSIDASE (Pyrococcushorikoshii) |
PF02449(Glyco_hydro_42) | 4 | LEU A 354GLU A 105TRP A 400SER A 353 | NonePO4 A 802 (-2.8A)NoneNone | 1.10A | 3dzgB-5gslA:2.2 | 3dzgB-5gslA:15.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gsm | EXO-BETA-D-GLUCOSAMINIDASE (Thermococcuskodakarensis) |
PF02449(Glyco_hydro_42) | 4 | LEU A 352GLU A 103TRP A 398SER A 351 | GCS A 801 (-4.9A)GCS A 801 (-2.9A)NoneNone | 1.11A | 3dzgB-5gsmA:2.2 | 3dzgB-5gsmA:16.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j0b | MYELOID CELL SURFACEANTIGEN CD33 (Homo sapiens) |
PF00047(ig)PF07686(V-set) | 4 | LEU A 210TRP A 179SER A 181THR A 185 | None | 1.29A | 3dzgB-5j0bA:undetectable | 3dzgB-5j0bA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k66 | NTA1P (Saccharomycescerevisiae) |
PF00795(CN_hydrolase) | 4 | LEU A 66ASP A 34SER A 89THR A 82 | None | 1.23A | 3dzgB-5k66A:undetectable | 3dzgB-5k66A:20.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5o6y | PEPTIDOGLYCANN-ACETYLGLUCOSAMINEDEACETYLASE (Bacillus cereus) |
no annotation | 4 | LEU B 232ASP B 81SER B 235THR B 197 | None5YA B 302 ( 2.5A)NoneNone | 1.15A | 3dzgB-5o6yB:undetectable | 3dzgB-5o6yB:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ueb | NEGOA.19184.A (Neisseriagonorrhoeae) |
PF14085(DUF4265) | 4 | LEU A 38GLU A 19SER A 104THR A 71 | None | 0.94A | 3dzgB-5uebA:undetectable | 3dzgB-5uebA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ysq | TM0415 (Thermotogamaritima) |
no annotation | 4 | LEU A 186ASP A 173SER A 189THR A 181 | NoneSO4 A 302 (-3.6A)NoneNone | 1.28A | 3dzgB-5ysqA:3.0 | 3dzgB-5ysqA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yu1 | LYSINECYCLODEAMINASE (Streptomycespristinaespiralis) |
no annotation | 4 | LEU A 243GLU A 266ASP A 300THR A 209 | NoneNone NA A 401 (-3.6A)NAD A 402 (-4.0A) | 1.07A | 3dzgB-5yu1A:2.4 | 3dzgB-5yu1A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ao3 | GASDERMIN-D (Mus musculus) |
no annotation | 4 | LEU A 292ASP A 288TRP A 418SER A 470 | None | 1.07A | 3dzgB-6ao3A:undetectable | 3dzgB-6ao3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6exn | PRE-MRNA-SPLICINGFACTOR CLF1 (Saccharomycescerevisiae) |
no annotation | 4 | LEU S 92GLU S 89SER S 96THR S 128 | None | 1.25A | 3dzgB-6exnS:undetectable | 3dzgB-6exnS:undetectable |