SIMILAR PATTERNS OF AMINO ACIDS FOR 3DTU_D_CUD3
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ar1 | CYTOCHROME C OXIDASE (Paracoccusdenitrificans) |
PF00116(COX2)PF02790(COX2_TM) | 3 | CYH B 216CYH B 220HIS B 224 | CU B 271 (-2.2A) CU B 270 (-2.1A) CU B 270 ( 3.2A) | 0.19A | 3dtuD-1ar1B:30.7 | 3dtuD-1ar1B:48.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cyq | INTRON-ENCODEDHOMING ENDONUCLEASEI-PPOI (Physarumpolycephalum) |
no annotation | 3 | CYH A 41CYH A 100HIS A 110 | ZN A 602 (-2.3A) ZN A 602 (-2.3A) ZN A 602 (-3.2A) | 0.37A | 3dtuD-1cyqA:0.0 | 3dtuD-1cyqA:18.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cyx | CYOA (Escherichiacoli) |
PF00116(COX2)PF06481(COX_ARM) | 3 | CYH A 207CYH A 211HIS A 215 | CUA A 316 (-2.1A)CUA A 316 (-2.2A)CUA A 316 (-2.8A) | 0.23A | 3dtuD-1cyxA:13.4 | 3dtuD-1cyxA:21.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1d0q | DNA PRIMASE (Geobacillusstearothermophilus) |
PF01807(zf-CHC2) | 3 | CYH A 64CYH A 40HIS A 43 | ZN A 151 (-2.4A) ZN A 151 (-2.3A) ZN A 151 (-3.1A) | 0.86A | 3dtuD-1d0qA:0.0 | 3dtuD-1d0qA:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1de6 | L-RHAMNOSE ISOMERASE (Escherichiacoli) |
PF06134(RhaA) | 3 | CYH A 143CYH A 170HIS A 169 | None | 0.65A | 3dtuD-1de6A:0.0 | 3dtuD-1de6A:19.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fp0 | KAP-1 COREPRESSOR (Homo sapiens) |
PF00628(PHD) | 3 | CYH A 28CYH A 51HIS A 48 | ZN A 90 (-2.3A) ZN A 90 (-2.2A) ZN A 90 (-2.7A) | 0.59A | 3dtuD-1fp0A:undetectable | 3dtuD-1fp0A:16.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fwx | NITROUS OXIDEREDUCTASE (Paracoccusdenitrificans) |
PF13473(Cupredoxin_1) | 3 | CYH A 561CYH A 565HIS A 569 | CUA A4701 (-2.2A)CUA A4701 (-2.2A)CUA A4701 (-3.0A) | 0.19A | 3dtuD-1fwxA:9.2 | 3dtuD-1fwxA:16.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1qle | CYTOCHROME C OXIDASEPOLYPEPTIDE II (Paracoccusdenitrificans) |
PF00116(COX2)PF02790(COX2_TM) | 3 | CYH B 216CYH B 220HIS B 224 | CUA B 301 (-2.1A)CUA B 301 (-2.0A)CUA B 301 (-3.1A) | 0.22A | 3dtuD-1qleB:29.5 | 3dtuD-1qleB:56.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1qni | NITROUS-OXIDEREDUCTASE (Marinobacterhydrocarbonoclasticus) |
no annotation | 3 | CYH A 561CYH A 565HIS A 569 | CUA A 701 (-2.2A)CUA A 701 (-2.2A)CUA A 701 (-3.0A) | 0.20A | 3dtuD-1qniA:9.3 | 3dtuD-1qniA:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tbn | PROTEIN KINASE C,GAMMA TYPE (Rattus rattus) |
PF00130(C1_1) | 3 | CYH A 143CYH A 118HIS A 117 | ZN A 2 (-2.3A) ZN A 2 (-2.3A)None | 0.85A | 3dtuD-1tbnA:undetectable | 3dtuD-1tbnA:15.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1urj | MAJOR DNA-BINDINGPROTEIN (Humanalphaherpesvirus1) |
PF00747(Viral_DNA_bp) | 3 | CYH A 499CYH A 510HIS A 512 | ZN A2131 (-2.3A) ZN A2131 (-2.4A) ZN A2131 (-2.8A) | 0.64A | 3dtuD-1urjA:0.0 | 3dtuD-1urjA:12.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vrq | SARCOSINE OXIDASEDELTA SUBUNIT (Corynebacteriumsp. U-96) |
PF04267(SoxD) | 3 | CYH D 6CYH D 63HIS D 59 | ZN D1006 (-2.4A) ZN D1006 (-2.4A) ZN D1006 (-3.2A) | 0.51A | 3dtuD-1vrqD:undetectable | 3dtuD-1vrqD:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vrq | SARCOSINE OXIDASEDELTA SUBUNIT (Corynebacteriumsp. U-96) |
PF04267(SoxD) | 3 | CYH D 9CYH D 63HIS D 59 | ZN D1006 (-2.3A) ZN D1006 (-2.4A) ZN D1006 (-3.2A) | 0.68A | 3dtuD-1vrqD:undetectable | 3dtuD-1vrqD:15.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wir | PROTEIN ARGININEN-METHYLTRANSFERASE3 (Mus musculus) |
no annotation | 3 | CYH A 18CYH A 35HIS A 34 | ZN A 201 (-2.3A) ZN A 201 ( 4.3A) ZN A 201 (-3.4A) | 0.83A | 3dtuD-1wirA:undetectable | 3dtuD-1wirA:17.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wo3 | CREB BINDING PROTEIN (Homo sapiens) |
no annotation | 3 | CYH A 23CYH A 10HIS A 19 | ZN A 26 (-2.3A) ZN A 26 (-2.3A) ZN A 26 (-3.0A) | 0.83A | 3dtuD-1wo3A:undetectable | 3dtuD-1wo3A:6.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wo5 | CREB BINDING PROTEIN (Homo sapiens) |
no annotation | 3 | CYH A 23CYH A 10HIS A 19 | ZN A 26 (-2.3A) ZN A 26 (-2.3A) ZN A 26 (-3.0A) | 0.66A | 3dtuD-1wo5A:undetectable | 3dtuD-1wo5A:5.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wo6 | CREB BINDING PROTEIN (Homo sapiens) |
no annotation | 3 | CYH A 23CYH A 10HIS A 19 | ZN A 26 (-2.3A) ZN A 26 (-2.3A) ZN A 26 (-3.1A) | 0.86A | 3dtuD-1wo6A:undetectable | 3dtuD-1wo6A:4.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wo7 | CREB BINDING PROTEIN (Homo sapiens) |
no annotation | 3 | CYH A 23CYH A 5HIS A 19 | ZN A 26 (-2.3A) ZN A 26 (-2.3A) ZN A 26 (-3.1A) | 0.87A | 3dtuD-1wo7A:undetectable | 3dtuD-1wo7A:5.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wo7 | CREB BINDING PROTEIN (Homo sapiens) |
no annotation | 3 | CYH A 23CYH A 10HIS A 19 | ZN A 26 (-2.3A) ZN A 26 (-2.3A) ZN A 26 (-3.1A) | 0.72A | 3dtuD-1wo7A:undetectable | 3dtuD-1wo7A:5.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1y8f | UNC-13 HOMOLOG A (Rattusnorvegicus) |
PF00130(C1_1) | 3 | CYH A 600CYH A 616HIS A 567 | ZN A 701 (-2.3A) ZN A 701 (-2.5A) ZN A 701 (-3.3A) | 0.73A | 3dtuD-1y8fA:undetectable | 3dtuD-1y8fA:9.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z05 | TRANSCRIPTIONALREGULATOR, ROKFAMILY (Vibrio cholerae) |
PF00480(ROK) | 3 | CYH A 257CYH A 262HIS A 245 | ZN A 406 (-2.3A) ZN A 406 (-2.2A) ZN A 406 (-3.2A) | 0.66A | 3dtuD-1z05A:undetectable | 3dtuD-1z05A:20.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1z6r | MLC PROTEIN (Escherichiacoli) |
PF00480(ROK) | 3 | CYH A 259CYH A 264HIS A 247 | ZN A 501 (-2.2A) ZN A 501 (-2.2A) ZN A 501 (-3.0A) | 0.70A | 3dtuD-1z6rA:undetectable | 3dtuD-1z6rA:21.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2aa4 | PUTATIVEN-ACETYLMANNOSAMINEKINASE (Escherichiacoli) |
PF00480(ROK) | 3 | CYH A 168CYH A 173HIS A 156 | ZN A1001 (-2.2A) ZN A1001 (-2.2A) ZN A1001 (-3.2A) | 0.69A | 3dtuD-2aa4A:undetectable | 3dtuD-2aa4A:20.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ap1 | PUTATIVE REGULATORPROTEIN (Salmonellaenterica) |
PF00480(ROK) | 3 | CYH A 179CYH A 184HIS A 157 | ZN A 304 (-2.3A) ZN A 304 (-2.3A) ZN A 304 (-3.2A) | 0.67A | 3dtuD-2ap1A:undetectable | 3dtuD-2ap1A:20.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b5l | NONSTRUCTURALPROTEIN V (Mammalianrubulavirus 5) |
PF13008(zf-Paramyx-P)PF14313(Soyouz_module) | 3 | CYH C 215CYH C 190HIS C 171 | ZN C3002 (-2.2A) ZN C3002 (-2.2A) ZN C3002 (-4.0A) | 0.59A | 3dtuD-2b5lC:undetectable | 3dtuD-2b5lC:21.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2be7 | ASPARTATECARBAMOYLTRANSFERASEREGULATORY CHAIN (Moritellaprofunda) |
PF01948(PyrI)PF02748(PyrI_C) | 3 | CYH D 108CYH D 113HIS D 116 | ZN D1108 (-2.2A) ZN D1108 (-2.3A)None | 0.83A | 3dtuD-2be7D:undetectable | 3dtuD-2be7D:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bl6 | NUCLEOCAPSID PROTEINP11 (Equineinfectiousanemia virus) |
PF00098(zf-CCHC) | 3 | CYH A 56CYH A 46HIS A 51 | ZN A1060 (-2.1A) ZN A1060 (-2.1A) ZN A1060 (-3.3A) | 0.77A | 3dtuD-2bl6A:undetectable | 3dtuD-2bl6A:8.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dan | ZINC FINGER MYNDDOMAIN CONTAININGPROTEIN 10 (Homo sapiens) |
PF01753(zf-MYND) | 3 | CYH A 29CYH A 54HIS A 50 | ZN A 201 (-2.3A) ZN A 201 (-2.3A) ZN A 201 (-3.4A) | 0.87A | 3dtuD-2danA:undetectable | 3dtuD-2danA:12.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2dj8 | PROTEIN CBFA2T1 (Homo sapiens) |
PF01753(zf-MYND) | 3 | CYH A 29CYH A 54HIS A 50 | ZN A 401 (-2.1A) ZN A 401 (-2.3A) ZN A 401 (-3.2A) | 0.74A | 3dtuD-2dj8A:undetectable | 3dtuD-2dj8A:11.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e73 | PROTEIN KINASE CGAMMA TYPE (Homo sapiens) |
PF00130(C1_1) | 3 | CYH A 77CYH A 52HIS A 51 | ZN A 201 (-2.2A) ZN A 201 (-2.2A)None | 0.83A | 3dtuD-2e73A:undetectable | 3dtuD-2e73A:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fpr | HISTIDINEBIOSYNTHESISBIFUNCTIONAL PROTEINHISB (Escherichiacoli) |
PF08645(PNK3P) | 3 | CYH A 94CYH A 102HIS A 96 | ZN A 502 (-2.3A) ZN A 502 (-2.3A) ZN A 502 (-3.2A) | 0.73A | 3dtuD-2fprA:undetectable | 3dtuD-2fprA:19.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gah | HETEROTETRAMERICSARCOSINE OXIDASEDELTA-SUBUNIT (Stenotrophomonasmaltophilia) |
PF04267(SoxD) | 3 | CYH D 6CYH D 63HIS D 59 | ZN D 101 (-2.2A) ZN D 101 (-2.2A) ZN D 101 (-3.2A) | 0.48A | 3dtuD-2gahD:undetectable | 3dtuD-2gahD:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gah | HETEROTETRAMERICSARCOSINE OXIDASEDELTA-SUBUNIT (Stenotrophomonasmaltophilia) |
PF04267(SoxD) | 3 | CYH D 9CYH D 63HIS D 59 | ZN D 101 (-2.2A) ZN D 101 (-2.2A) ZN D 101 (-3.2A) | 0.76A | 3dtuD-2gahD:undetectable | 3dtuD-2gahD:14.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jz8 | UNCHARACTERIZEDPROTEIN BH09830 (Bartonellahenselae) |
PF10276(zf-CHCC) | 3 | CYH A 54CYH A 27HIS A 38 | ZN A 150 (-2.1A) ZN A 150 (-2.1A) ZN A 150 (-3.1A) | 0.85A | 3dtuD-2jz8A:undetectable | 3dtuD-2jz8A:17.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2kyu | HISTONE-LYSINEN-METHYLTRANSFERASEMLL (Homo sapiens) |
PF00628(PHD) | 3 | CYH A 11CYH A 38HIS A 35 | ZN A 81 (-2.3A) ZN A 81 (-2.4A) ZN A 81 (-3.1A) | 0.63A | 3dtuD-2kyuA:undetectable | 3dtuD-2kyuA:13.39 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l0b | E3 UBIQUITIN-PROTEINLIGASE PRAJA-1 (Homo sapiens) |
PF13639(zf-RING_2) | 3 | CYH A 43CYH A 69HIS A 66 | ZN A 143 (-2.4A) ZN A 143 (-2.4A) ZN A 143 (-3.1A) | 0.75A | 3dtuD-2l0bA:undetectable | 3dtuD-2l0bA:17.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lq6 | BROMODOMAIN-CONTAINING PROTEIN 1 (Homo sapiens) |
PF13771(zf-HC5HC2H) | 3 | CYH A 346CYH A 385HIS A 388 | ZN A 402 (-2.1A) ZN A 402 (-2.1A) ZN A 402 (-3.3A) | 0.76A | 3dtuD-2lq6A:undetectable | 3dtuD-2lq6A:14.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lxw | XIAP-ASSOCIATEDFACTOR 1 (Homo sapiens) |
no annotation | 3 | CYH A 21CYH A 40HIS A 36 | ZN A 101 (-1.9A) ZN A 101 (-1.9A) ZN A 101 (-3.3A) | 0.86A | 3dtuD-2lxwA:undetectable | 3dtuD-2lxwA:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lxw | XIAP-ASSOCIATEDFACTOR 1 (Homo sapiens) |
no annotation | 3 | CYH A 24CYH A 40HIS A 36 | ZN A 101 (-1.9A) ZN A 101 (-1.9A) ZN A 101 (-3.3A) | 0.86A | 3dtuD-2lxwA:undetectable | 3dtuD-2lxwA:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2lzu | LIMDOMAIN-CONTAININGPROTEIN 2 (Homo sapiens) |
PF00412(LIM) | 3 | CYH A 43CYH A 67HIS A 64 | ZN A 201 (-2.2A) ZN A 201 (-2.2A) ZN A 201 (-3.0A) | 0.52A | 3dtuD-2lzuA:undetectable | 3dtuD-2lzuA:13.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2m1s | RING FINGER PROTEINZ (Lassamammarenavirus) |
PF03854(zf-P11) | 3 | CYH A 64CYH A 44HIS A 47 | ZN A 101 (-2.3A) ZN A 101 (-2.3A) ZN A 101 (-3.1A) | 0.76A | 3dtuD-2m1sA:undetectable | 3dtuD-2m1sA:14.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2n94 | BOX C/D SNORNAPROTEIN 1 (Saccharomycescerevisiae) |
PF04438(zf-HIT) | 3 | CYH A 39CYH A 20HIS A 33 | ZN A 102 (-2.3A) ZN A 102 (-2.3A) ZN A 102 (-2.9A) | 0.87A | 3dtuD-2n94A:undetectable | 3dtuD-2n94A:8.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2naa | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-36 AND H4LYSINE-20 SPECIFIC (Mus musculus) |
no annotation | 3 | CYH A 9CYH A 34HIS A 31 | ZN A 101 (-2.3A) ZN A 101 (-2.3A) ZN A 101 (-3.0A) | 0.63A | 3dtuD-2naaA:undetectable | 3dtuD-2naaA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2naa | HISTONE-LYSINEN-METHYLTRANSFERASE,H3 LYSINE-36 AND H4LYSINE-20 SPECIFIC (Mus musculus) |
no annotation | 3 | CYH A 26CYH A 47HIS A 50 | ZN A 102 (-2.2A) ZN A 102 (-2.3A) ZN A 102 (-2.8A) | 0.85A | 3dtuD-2naaA:undetectable | 3dtuD-2naaA:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2od1 | PROTEIN CBFA2T1 (Homo sapiens) |
PF01753(zf-MYND) | 3 | CYH A 674CYH A 699HIS A 695 | ZN A 902 (-2.3A) ZN A 902 (-2.3A) ZN A 902 (-3.1A) | 0.83A | 3dtuD-2od1A:undetectable | 3dtuD-2od1A:10.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2odd | PROTEIN CBFA2T1 (Homo sapiens) |
PF01753(zf-MYND) | 3 | CYH A 674CYH A 699HIS A 695 | ZN A 2 (-2.3A) ZN A 2 (-2.3A) ZN A 2 (-3.2A) | 0.84A | 3dtuD-2oddA:undetectable | 3dtuD-2oddA:10.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rmn | TUMOR PROTEIN 63 (Homo sapiens) |
PF00870(P53) | 3 | CYH A 205CYH A 269HIS A 208 | ZN A 1 (-2.1A) ZN A 1 (-2.1A) ZN A 1 (-3.3A) | 0.84A | 3dtuD-2rmnA:undetectable | 3dtuD-2rmnA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2rmn | TUMOR PROTEIN 63 (Homo sapiens) |
PF00870(P53) | 3 | CYH A 273CYH A 269HIS A 208 | ZN A 1 (-2.2A) ZN A 1 (-2.1A) ZN A 1 (-3.3A) | 0.78A | 3dtuD-2rmnA:undetectable | 3dtuD-2rmnA:21.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vl6 | MINICHROMOSOMEMAINTENANCE PROTEINMCM (Sulfolobussolfataricus) |
PF14551(MCM_N)PF17207(MCM_OB) | 3 | CYH A 171CYH A 149HIS A 144 | ZN A1266 (-2.0A) ZN A1266 (-2.2A) ZN A1266 (-3.1A) | 0.57A | 3dtuD-2vl6A:undetectable | 3dtuD-2vl6A:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vy5 | U11/U12 SMALLNUCLEARRIBONUCLEOPROTEIN 48KDA PROTEIN (Homo sapiens) |
PF05253(zf-U11-48K) | 3 | CYH A 78CYH A 58HIS A 64 | ZN A1088 (-2.3A) ZN A1088 (-2.3A) ZN A1088 (-2.9A) | 0.83A | 3dtuD-2vy5A:undetectable | 3dtuD-2vy5A:8.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vy5 | U11/U12 SMALLNUCLEARRIBONUCLEOPROTEIN 48KDA PROTEIN (Homo sapiens) |
PF05253(zf-U11-48K) | 3 | CYH A 78CYH A 58HIS A 74 | ZN A1088 (-2.3A) ZN A1088 (-2.3A) ZN A1088 (-2.9A) | 0.81A | 3dtuD-2vy5A:undetectable | 3dtuD-2vy5A:8.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xoc | E3 UBIQUITIN-PROTEINLIGASE CHFR (Homo sapiens) |
no annotation | 3 | CYH A 524CYH A 532HIS A 519 | ZN A 993 ( 2.4A) ZN A 993 (-2.4A)None | 0.77A | 3dtuD-2xocA:undetectable | 3dtuD-2xocA:19.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yev | CYTOCHROME C OXIDASESUBUNIT 2 (Thermusthermophilus) |
PF00034(Cytochrom_C)PF00116(COX2)PF02790(COX2_TM) | 3 | CYH B 197CYH B 201HIS B 205 | CUA B 585 (-2.4A)CUA B 585 (-2.3A)CUA B 585 (-3.1A) | 0.17A | 3dtuD-2yevB:17.0 | 3dtuD-2yevB:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yre | F-BOX ONLY PROTEIN30 (Homo sapiens) |
PF15965(zf-TRAF_2) | 3 | CYH A 10CYH A 28HIS A 42 | ZN A 401 ( 2.2A) ZN A 401 ( 2.2A) ZN A 501 ( 3.2A) | 0.86A | 3dtuD-2yreA:undetectable | 3dtuD-2yreA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3av6 | DNA(CYTOSINE-5)-METHYLTRANSFERASE 1 (Mus musculus) |
PF00145(DNA_methylase)PF01426(BAH)PF02008(zf-CXXC)PF12047(DNMT1-RFD) | 3 | CYH A 823CYH A 897HIS A 798 | ZN A2004 (-2.2A) ZN A2004 (-2.2A)None | 0.86A | 3dtuD-3av6A:undetectable | 3dtuD-3av6A:11.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3eo3 | BIFUNCTIONALUDP-N-ACETYLGLUCOSAMINE2-EPIMERASE/N-ACETYLMANNOSAMINE KINASE (Homo sapiens) |
PF00480(ROK) | 3 | CYH A 581CYH A 586HIS A 569 | ZN A 801 (-2.3A) ZN A 801 (-2.2A) ZN A 801 (-3.1A) | 0.68A | 3dtuD-3eo3A:undetectable | 3dtuD-3eo3A:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3esr | D,D-HEPTOSE1,7-BISPHOSPHATEPHOSPHATASE (Escherichiacoli) |
PF13242(Hydrolase_like) | 3 | CYH A 112CYH A 127HIS A 114 | ZN A 212 (-2.2A) ZN A 212 (-2.4A) ZN A 212 (-3.4A) | 0.70A | 3dtuD-3esrA:undetectable | 3dtuD-3esrA:21.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fdi | UNCHARACTERIZEDPROTEIN (Eubacteriumventriosum) |
PF13189(Cytidylate_kin2) | 3 | CYH A 161CYH A 104HIS A 157 | None | 0.78A | 3dtuD-3fdiA:undetectable | 3dtuD-3fdiA:22.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8e | D,D-HEPTOSE1,7-BISPHOSPHATEPHOSPHATASE (Escherichiacoli) |
PF13242(Hydrolase_like) | 3 | CYH A 92CYH A 107HIS A 94 | ZN A 801 (-2.2A) ZN A 801 (-2.3A) ZN A 801 (-3.2A) | 0.70A | 3dtuD-3l8eA:undetectable | 3dtuD-3l8eA:21.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l8h | PUTATIVE HALOACIDDEHALOGENASE-LIKEHYDROLASE (Bordetellabronchiseptica) |
PF13242(Hydrolase_like) | 3 | CYH A 89CYH A 97HIS A 91 | ZN A 901 (-2.3A) ZN A 901 (-2.2A) ZN A 901 (-3.1A) | 0.83A | 3dtuD-3l8hA:undetectable | 3dtuD-3l8hA:22.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mi9 | PROTEIN TAT (Humanimmunodeficiencyvirus 1) |
PF00539(Tat) | 3 | CYH C 22CYH C 34HIS C 33 | ZN C 87 (-2.3A) ZN C 87 (-2.3A) ZN C 87 (-3.3A) | 0.77A | 3dtuD-3mi9C:undetectable | 3dtuD-3mi9C:15.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3om3 | CYTOCHROME C OXIDASESUBUNIT 2 (Rhodobactersphaeroides) |
PF00116(COX2)PF02790(COX2_TM) | 3 | CYH B 252CYH B 256HIS B 260 | CU1 B 288 ( 2.2A)CU1 B 287 ( 2.3A)CU1 B 287 (-3.0A) | 0.08A | 3dtuD-3om3B:36.2 | 3dtuD-3om3B:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s38 | CYTOCHROME C OXIDASESUBUNIT 2 (Thermusthermophilus) |
PF00116(COX2)PF09125(COX2-transmemb) | 3 | CYH B 149CYH B 153HIS B 157 | CUA B 802 (-1.9A)CUA B 802 (-2.0A)CUA B 802 (-2.7A) | 0.36A | 3dtuD-3s38B:8.9 | 3dtuD-3s38B:22.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sbq | NITROUS-OXIDEREDUCTASE (Pseudomonasstutzeri) |
no annotation | 3 | CYH A 618CYH A 622HIS A 626 | CUA A 701 (-2.2A)CUA A 701 (-2.3A)CUA A 701 (-3.0A) | 0.24A | 3dtuD-3sbqA:7.6 | 3dtuD-3sbqA:17.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3u9g | ZINC FINGERCCCH-TYPE ANTIVIRALPROTEIN 1 (Rattusnorvegicus) |
no annotation | 3 | CYH A 96CYH A 106HIS A 110 | ZN A 227 (-2.3A) ZN A 227 (-2.4A) ZN A 227 (-3.1A) | 0.86A | 3dtuD-3u9gA:undetectable | 3dtuD-3u9gA:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vgl | GLUCOKINASE (Streptomycesgriseus) |
PF00480(ROK) | 3 | CYH A 169CYH A 174HIS A 157 | ZN A 322 (-2.2A) ZN A 322 (-2.2A) ZN A 322 ( 3.2A) | 0.66A | 3dtuD-3vglA:undetectable | 3dtuD-3vglA:23.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vov | GLUCOKINASE (Thermusthermophilus) |
PF00480(ROK) | 3 | CYH A 171CYH A 176HIS A 159 | ZN A 401 (-2.3A) ZN A 401 (-2.3A) ZN A 401 (-3.1A) | 0.70A | 3dtuD-3vovA:undetectable | 3dtuD-3vovA:21.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vpb | ALPHA-AMINOADIPATECARRIER PROTEIN LYSW (Sulfurisphaeratokodaii) |
no annotation | 3 | CYH E 6CYH E 29HIS E 27 | ZN E 100 (-2.2A) ZN E 100 (-2.3A) ZN E 100 (-3.2A) | 0.51A | 3dtuD-3vpbE:undetectable | 3dtuD-3vpbE:12.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3zj2 | NUCLEARPOLYADENYLATEDRNA-BINDING PROTEINNAB2 (Saccharomycescerevisiae) |
PF14608(zf-CCCH_2) | 3 | CYH A 351CYH A 340HIS A 355 | ZN A 501 (-2.4A) ZN A 501 (-2.4A) ZN A 501 (-3.6A) | 0.87A | 3dtuD-3zj2A:undetectable | 3dtuD-3zj2A:13.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a24 | DEFORMED EPIDERMALAUTOREGULATORYFACTOR 1 HOMOLOG (Homo sapiens) |
PF01753(zf-MYND) | 3 | CYH A 515CYH A 540HIS A 536 | ZN A 602 (-2.3A) ZN A 602 (-2.3A) ZN A 602 (-3.1A) | 0.81A | 3dtuD-4a24A:undetectable | 3dtuD-4a24A:10.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cyk | PAB-DEPENDENTPOLY(A)-SPECIFICRIBONUCLEASE SUBUNITPAN3 (Saccharomycescerevisiae) |
no annotation | 3 | CYH A 30CYH A 14HIS A 34 | ZN A 42 (-2.2A) ZN A 42 (-2.3A) ZN A 42 (-3.1A) | 0.86A | 3dtuD-4cykA:undetectable | 3dtuD-4cykA:11.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4db3 | N-ACETYL-D-GLUCOSAMINE KINASE (Vibriovulnificus) |
PF00480(ROK) | 3 | CYH A 179CYH A 184HIS A 157 | ZN A 401 (-2.3A) ZN A 401 (-2.2A) ZN A 401 (-3.2A) | 0.74A | 3dtuD-4db3A:undetectable | 3dtuD-4db3A:19.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4e4w | DNA MISMATCH REPAIRPROTEIN MLH1DNA MISMATCH REPAIRPROTEIN PMS1 (Saccharomycescerevisiae;Saccharomycescerevisiae) |
PF16413(Mlh1_C)PF08676(MutL_C) | 3 | CYH B 817CYH A 769HIS B 850 | ZN B 901 (-2.4A) ZN B 902 ( 2.2A) ZN B 902 (-3.1A) | 0.81A | 3dtuD-4e4wB:undetectable | 3dtuD-4e4wB:20.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdg | MINICHROMOSOMEMAINTENANCE PROTEINMCM (Sulfolobussolfataricus) |
no annotation | 3 | CYH B 171CYH B 149HIS B 144 | ZN B 701 (-2.1A) ZN B 701 (-2.3A) ZN B 701 (-3.2A) | 0.76A | 3dtuD-4fdgB:undetectable | 3dtuD-4fdgB:16.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ggj | MITOCHONDRIALCARDIOLIPINHYDROLASE (Mus musculus) |
PF13091(PLDc_2) | 3 | CYH A 66CYH A 49HIS A 72 | ZN A 301 (-2.2A) ZN A 301 (-2.2A) ZN A 301 (-3.3A) | 0.71A | 3dtuD-4ggjA:undetectable | 3dtuD-4ggjA:20.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4i1s | NON-STRUCTURALPROTEIN V (Mammalianrubulavirus 5) |
PF13008(zf-Paramyx-P) | 3 | CYH B 215CYH B 190HIS B 171 | ZN B 302 (-2.2A) ZN B 302 (-2.4A) ZN B 302 (-3.0A) | 0.80A | 3dtuD-4i1sB:undetectable | 3dtuD-4i1sB:14.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lj0 | NAB2 (Chaetomiumthermophilum) |
PF14608(zf-CCCH_2) | 3 | CYH A 437CYH A 426HIS A 441 | ZN A 502 (-2.2A) A E 2 (-2.1A) ZN A 502 (-3.2A) | 0.85A | 3dtuD-4lj0A:undetectable | 3dtuD-4lj0A:11.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1j | CARBONIC ANHYDRASE (Sordariamacrospora) |
PF00484(Pro_CA) | 3 | CYH A 45CYH A 104HIS A 101 | ZN A 301 (-2.2A) ZN A 301 (-2.3A) ZN A 301 (-3.4A) | 0.86A | 3dtuD-4o1jA:undetectable | 3dtuD-4o1jA:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o1k | CARBONIC ANHYDRASE (Sordariamacrospora) |
PF00484(Pro_CA) | 3 | CYH A 56CYH A 115HIS A 112 | ZN A 301 (-2.3A) ZN A 301 (-2.2A) ZN A 301 (-3.3A) | 0.87A | 3dtuD-4o1kA:undetectable | 3dtuD-4o1kA:23.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ogr | PROTEIN TAT (Humanimmunodeficiencyvirus 1) |
PF00539(Tat) | 3 | CYH D 22CYH D 34HIS D 33 | ZN D 101 (-2.2A) ZN D 101 (-2.4A) ZN D 101 (-3.1A) | 0.84A | 3dtuD-4ogrD:undetectable | 3dtuD-4ogrD:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ozu | CORONIN (Toxoplasmagondii) |
PF00400(WD40)PF08953(DUF1899)PF16300(WD40_4) | 3 | CYH A 210CYH A 217HIS A 211 | NoneNoneTRS A 401 (-3.8A) | 0.86A | 3dtuD-4ozuA:undetectable | 3dtuD-4ozuA:21.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r7y | MINICHROMOSOMEMAINTENANCE PROTEINMCM, CELL DIVISIONCONTROL PROTEIN 21 (Pyrococcusfuriosus;Sulfolobussolfataricus) |
PF00493(MCM)PF14551(MCM_N)PF17207(MCM_OB) | 3 | CYH A 171CYH A 149HIS A 144 | ZN A2003 (-2.1A) ZN A2003 (-2.2A) ZN A2003 (-3.1A) | 0.56A | 3dtuD-4r7yA:undetectable | 3dtuD-4r7yA:18.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4rvo | PHENYLACETATE-COENZYME A LIGASE (Bacteroidesthetaiotaomicron) |
PF00501(AMP-binding)PF14535(AMP-binding_C_2) | 3 | CYH A 313CYH A 251HIS A 258 | ZN A 501 (-2.4A) ZN A 501 (-2.3A) ZN A 501 (-3.2A) | 0.85A | 3dtuD-4rvoA:undetectable | 3dtuD-4rvoA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u8h | CRYPTOCHROME-2PERIOD CIRCADIANPROTEIN HOMOLOG 2 (Mus musculus;Mus musculus) |
PF00875(DNA_photolyase)PF03441(FAD_binding_7)PF12114(Period_C) | 3 | CYH A 432CYH B1213HIS A 491 | ZN A2000 (-2.7A) ZN A2000 (-4.2A) ZN A2000 (-3.3A) | 0.83A | 3dtuD-4u8hA:undetectable | 3dtuD-4u8hA:16.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w9z | CYTOCHROME C OXIDASESUBUNIT 2 (Bradyrhizobiumdiazoefficiens) |
PF00116(COX2) | 3 | CYH A 229CYH A 233HIS A 237 | CU A 302 ( 2.3A) CU A 302 ( 2.2A) CU A 302 (-3.1A) | 0.14A | 3dtuD-4w9zA:20.5 | 3dtuD-4w9zA:28.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5a3c | SIR2 FAMILY PROTEIN (Streptococcuspyogenes) |
no annotation | 3 | CYH A 180CYH A 149HIS A 150 | ZN A1293 (-2.0A) ZN A1293 (-2.3A)None | 0.77A | 3dtuD-5a3cA:undetectable | 3dtuD-5a3cA:19.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5b5z | PTLCIB4 H88A MUTANT (Phaeodactylumtricornutum) |
no annotation | 3 | CYH A 46CYH A 126HIS A 102 | ZN A 500 (-2.2A) ZN A 500 (-2.3A) ZN A 500 (-3.3A) | 0.86A | 3dtuD-5b5zA:undetectable | 3dtuD-5b5zA:23.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bqk | ICP27 (Humanalphaherpesvirus1) |
PF05459(Herpes_UL69) | 3 | CYH A 400CYH A 483HIS A 479 | ZN A 601 (-2.1A) ZN A 601 (-2.3A) ZN A 601 (-3.2A) | 0.79A | 3dtuD-5bqkA:undetectable | 3dtuD-5bqkA:22.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5f7r | LMO0178 PROTEIN (Listeriamonocytogenes) |
no annotation | 3 | CYH E 256CYH E 261HIS E 244 | ZN E 503 (-2.2A) ZN E 503 (-2.3A) ZN E 503 ( 3.1A) | 0.74A | 3dtuD-5f7rE:undetectable | 3dtuD-5f7rE:18.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7s | E3 UBIQUITIN-PROTEINLIGASE LNX (Homo sapiens) |
no annotation | 3 | CYH D 95CYH D 118HIS D 113 | ZN D 204 (-2.3A) ZN D 204 (-2.3A) ZN D 204 (-3.2A) | 0.75A | 3dtuD-5h7sD:undetectable | 3dtuD-5h7sD:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5k5w | LIMITINGCO2-INDUCIBLEPROTEIN LCIB (Chlamydomonasreinhardtii) |
no annotation | 3 | CYH A 120CYH A 204HIS A 180 | ZN A 500 (-2.3A) ZN A 500 (-2.3A) ZN A 500 (-3.3A) | 0.84A | 3dtuD-5k5wA:undetectable | 3dtuD-5k5wA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5l2l | NAB2P (Saccharomycescerevisiae) |
PF14608(zf-CCCH_2) | 3 | CYH A 469CYH A 458HIS A 473 | ZN A 503 (-2.3A) ZN A 503 (-2.3A) ZN A 503 (-3.3A) | 0.86A | 3dtuD-5l2lA:undetectable | 3dtuD-5l2lA:10.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5lj3 | PRE-MRNA-SPLICINGFACTOR BUD31 (Saccharomycescerevisiae) |
PF01125(G10) | 3 | CYH L 145CYH L 108HIS L 147 | ZN L1002 (-2.6A) ZN L1002 ( 2.2A) U V 29 ( 4.2A) | 0.83A | 3dtuD-5lj3L:undetectable | 3dtuD-5lj3L:20.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5tte | E3 UBIQUITIN-PROTEINLIGASE ARIH1 (Homo sapiens) |
PF01485(IBR) | 3 | CYH B 372CYH B 389HIS B 382 | ZN B 602 (-2.4A) ZN B 602 (-2.4A) ZN B 602 (-3.2A) | 0.86A | 3dtuD-5tteB:undetectable | 3dtuD-5tteB:16.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5udh | E3 UBIQUITIN-PROTEINLIGASE ARIH1 (Homo sapiens) |
PF01485(IBR) | 3 | CYH A 281CYH A 297HIS A 283 | ZN A 603 (-2.2A) ZN A 603 (-2.2A)None | 0.80A | 3dtuD-5udhA:undetectable | 3dtuD-5udhA:18.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wuq | ANTI-SIGMA-W FACTORRSIW (Bacillussubtilis) |
PF13490(zf-HC2) | 3 | CYH C 3CYH C 37HIS C 30 | ZN C 301 (-2.3A) ZN C 301 (-2.3A) ZN C 301 (-3.7A) | 0.71A | 3dtuD-5wuqC:undetectable | 3dtuD-5wuqC:13.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x6m | MOTHERS AGAINSTDECAPENTAPLEGICHOMOLOG 5 (Mus musculus) |
no annotation | 3 | CYH B 65CYH B 110HIS B 127 | ZN B 201 (-3.0A) ZN B 201 (-2.1A) ZN B 201 (-3.0A) | 0.61A | 3dtuD-5x6mB:undetectable | 3dtuD-5x6mB:18.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y3r | DNA-DEPENDENTPROTEIN KINASECATALYTIC SUBUNIT (Homo sapiens) |
PF00454(PI3_PI4_kinase)PF02259(FAT)PF02260(FATC)PF08163(NUC194) | 3 | CYH C1135CYH C1176HIS C1175 | None | 0.70A | 3dtuD-5y3rC:undetectable | 3dtuD-5y3rC:5.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zb3 | - (-) |
no annotation | 3 | CYH A 333CYH A 427HIS A 423 | ZN A 500 (-2.3A) ZN A 500 (-2.3A) ZN A 500 (-3.3A) | 0.82A | 3dtuD-5zb3A:undetectable | 3dtuD-5zb3A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 9atc | ASPARTATETRANSCARBAMOYLASE (Escherichiacoli) |
PF01948(PyrI)PF02748(PyrI_C) | 3 | CYH B 109CYH B 114HIS B 117 | ZN B 1 (-2.3A) ZN B 1 (-2.2A)None | 0.77A | 3dtuD-9atcB:undetectable | 3dtuD-9atcB:20.95 |