SIMILAR PATTERNS OF AMINO ACIDS FOR 3DMT_C_CCSC166
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bbu | PROTEIN (LYSYL-TRNASYNTHETASE) (Escherichiacoli) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | SER A 488THR A 486ASN A 487TYR A 312 | None | 0.94A | 3dmtC-1bbuA:undetectable | 3dmtC-1bbuA:21.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1dbv | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Geobacillusstearothermophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN O 313TYR O 317ASN O 152TYR O 311 | NAD O 336 (-4.2A)NAD O 336 (-3.7A)NoneNone | 0.94A | 3dmtC-1dbvO:48.5 | 3dmtC-1dbvO:51.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1dbv | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Geobacillusstearothermophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER O 148THR O 150ASN O 152CYH O 153HIS O 176TYR O 311ASN O 313TYR O 317 | SO4 O 339 (-2.9A)SO4 O 339 ( 4.5A)NoneNoneNoneNoneNAD O 336 (-4.2A)NAD O 336 (-3.7A) | 0.31A | 3dmtC-1dbvO:48.5 | 3dmtC-1dbvO:51.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e1t | LYSYL-TRNASYNTHETASE, HEATINDUCIBLE (Escherichiacoli) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | SER A 488THR A 486ASN A 487TYR A 312 | NoneNoneNoneGOL A 605 (-4.4A) | 0.87A | 3dmtC-1e1tA:undetectable | 3dmtC-1e1tA:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ezf | FARNESYL-DIPHOSPHATEFARNESYLTRANSFERASE (Homo sapiens) |
PF00494(SQS_PSY) | 4 | SER A 355ASN A 260CYH A 258ASN A 265 | None | 1.01A | 3dmtC-1ezfA:undetectable | 3dmtC-1ezfA:20.37 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gae | D-GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE (Escherichiacoli) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 7 | SER O 148THR O 150ASN O 152CYH O 153HIS O 176TYR O 311TYR O 317 | NoneNoneNoneNoneNoneNoneNAD O 336 ( 3.9A) | 0.30A | 3dmtC-1gaeO:46.6 | 3dmtC-1gaeO:51.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1gw1 | MANNANENDO-1,4-BETA-MANNOSIDASE (Cellvibriojaponicus) |
PF02156(Glyco_hydro_26) | 5 | SER A 95THR A 97ASN A 99HIS A 77ASN A 362 | None | 1.02A | 3dmtC-1gw1A:undetectable | 3dmtC-1gw1A:21.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gyq | PROTEIN(GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE) (Leishmaniamexicana) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 335TYR A 339ASN A 169TYR A 333 | NBD A 361 (-3.9A)NBD A 361 (-3.6A)NoneNone | 0.91A | 3dmtC-1gyqA:55.9 | 3dmtC-1gyqA:84.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1gyq | PROTEIN(GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE) (Leishmaniamexicana) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 165THR A 167ASN A 169CYH A 170HIS A 194TYR A 333ASN A 335TYR A 339 | NoneNoneNoneNoneNoneNoneNBD A 361 (-3.9A)NBD A 361 (-3.6A) | 0.27A | 3dmtC-1gyqA:55.9 | 3dmtC-1gyqA:84.12 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hdg | HOLO-D-GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE (Thermotogamaritima) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN O 313TYR O 317ASN O 152TYR O 311 | NAD O 336 (-3.9A)NAD O 336 (-3.5A)NoneNone | 0.99A | 3dmtC-1hdgO:46.9 | 3dmtC-1hdgO:47.88 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hdg | HOLO-D-GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE (Thermotogamaritima) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 7 | SER O 148THR O 150ASN O 152HIS O 176TYR O 311ASN O 313TYR O 317 | SO4 O 339 (-2.8A)SO4 O 339 (-3.5A)NoneSO4 O 339 (-4.4A)NoneNAD O 336 (-3.9A)NAD O 336 (-3.5A) | 0.33A | 3dmtC-1hdgO:46.9 | 3dmtC-1hdgO:47.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1igy | IGG1 INTACT ANTIBODYMAB61.1.3 (Mus musculus) |
PF07654(C1-set)PF07686(V-set) | 4 | THR B 57ASN B 58TYR B 59TYR B 50 | None | 1.02A | 3dmtC-1igyB:undetectable | 3dmtC-1igyB:20.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jn0 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEA (Spinaciaoleracea) |
no annotation | 4 | ASN O 313TYR O 317ASN O 152TYR O 311 | NDP O6335 (-3.9A)NDP O6335 (-3.4A)NoneNone | 0.85A | 3dmtC-1jn0O:48.9 | 3dmtC-1jn0O:44.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1jn0 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEA (Spinaciaoleracea) |
no annotation | 8 | SER O 148THR O 150ASN O 152CYH O 153HIS O 176TYR O 311ASN O 313TYR O 317 | SO4 O6337 (-3.5A)SO4 O6337 (-3.9A)NoneNoneNoneNoneNDP O6335 (-3.9A)NDP O6335 (-3.4A) | 0.36A | 3dmtC-1jn0O:48.9 | 3dmtC-1jn0O:44.97 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1obf | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Achromobacterxylosoxidans) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 7 | SER O 153THR O 155ASN O 157CYH O 158HIS O 181TYR O 314ASN O 316 | SO4 O 342 (-2.8A)SO4 O 342 ( 4.4A)NoneNoneNoneNoneNone | 0.34A | 3dmtC-1obfO:45.2 | 3dmtC-1obfO:47.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1s2n | EXTRACELLULARSUBTILISIN-LIKESERINE PROTEINASE (Vibrio sp.PA-44) |
PF00082(Peptidase_S8) | 4 | SER A 206THR A 77HIS A 225TYR A 83 | None | 1.02A | 3dmtC-1s2nA:4.1 | 3dmtC-1s2nA:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1t1u | CHOLINEO-ACETYLTRANSFERASE (Rattusnorvegicus) |
PF00755(Carn_acyltransf) | 4 | SER A 550CYH A 584ASN A 575TYR A 574 | None | 0.96A | 3dmtC-1t1uA:undetectable | 3dmtC-1t1uA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1uw1 | ARTIFICIALNUCLEOTIDE BINDINGPROTEIN (ANBP) (syntheticconstruct) |
no annotation | 4 | ASN A 32CYH A 46ASN A 44TYR A 43 | ADP A1074 ( 4.9A) ZN A1075 (-2.4A)NoneADP A1074 (-3.6A) | 0.94A | 3dmtC-1uw1A:undetectable | 3dmtC-1uw1A:12.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1vc2 | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Thermusthermophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 311TYR A 315ASN A 152TYR A 309 | NAD A 336 (-3.8A)NAD A 336 (-3.5A)NoneNone | 1.00A | 3dmtC-1vc2A:27.8 | 3dmtC-1vc2A:46.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1vc2 | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Thermusthermophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 7 | SER A 148THR A 150ASN A 152HIS A 176TYR A 309ASN A 311TYR A 315 | NoneNoneNoneNoneNoneNAD A 336 (-3.8A)NAD A 336 (-3.5A) | 0.43A | 3dmtC-1vc2A:27.8 | 3dmtC-1vc2A:46.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ywg | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Plasmodiumfalciparum) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN O 319TYR O 323ASN O 156TYR O 317 | NAD O 401 (-3.6A)NAD O 401 (-3.7A)NoneNone | 0.95A | 3dmtC-1ywgO:48.3 | 3dmtC-1ywgO:50.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1ywg | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Plasmodiumfalciparum) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER O 152THR O 154ASN O 156CYH O 157HIS O 180TYR O 317ASN O 319TYR O 323 | NoneNoneNoneNoneNoneNoneNAD O 401 (-3.6A)NAD O 401 (-3.7A) | 0.33A | 3dmtC-1ywgO:48.3 | 3dmtC-1ywgO:50.28 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2d2i | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Synechococcussp.) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 318TYR A 322ASN A 158TYR A 316 | NAP A1341 (-3.9A)NAP A1341 (-3.7A)NoneNone | 0.91A | 3dmtC-2d2iA:49.3 | 3dmtC-2d2iA:47.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2d2i | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Synechococcussp.) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 154THR A 156ASN A 158CYH A 159HIS A 182TYR A 316ASN A 318TYR A 322 | SO4 A1339 (-2.9A)SO4 A1339 ( 4.3A)NoneNoneNoneNoneNAP A1341 (-3.9A)NAP A1341 (-3.7A) | 0.32A | 3dmtC-2d2iA:49.3 | 3dmtC-2d2iA:47.65 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ep7 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Aquifexaeolicus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 322TYR A 326ASN A 155TYR A 320 | NAD A 401 (-3.9A)NAD A 401 ( 3.7A)NoneNone | 0.97A | 3dmtC-2ep7A:46.8 | 3dmtC-2ep7A:48.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ep7 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Aquifexaeolicus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 151THR A 153ASN A 155CYH A 156HIS A 179TYR A 320ASN A 322TYR A 326 | NoneNoneNoneNoneNoneNoneNAD A 401 (-3.9A)NAD A 401 ( 3.7A) | 0.32A | 3dmtC-2ep7A:46.8 | 3dmtC-2ep7A:48.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fy2 | CHOLINEO-ACETYLTRANSFERASE (Homo sapiens) |
PF00755(Carn_acyltransf) | 4 | SER A 540CYH A 574ASN A 565TYR A 564 | None | 0.90A | 3dmtC-2fy2A:undetectable | 3dmtC-2fy2A:19.68 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2i5p | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE1 (Kluyveromycesmarxianus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 6 | SER O 148THR O 150ASN O 152CYH O 153TYR O 311TYR O 317 | None | 0.29A | 3dmtC-2i5pO:41.8 | 3dmtC-2i5pO:51.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2i5p | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE1 (Kluyveromycesmarxianus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | SER O 148THR O 150TYR O 311ASN O 313TYR O 317 | None | 0.81A | 3dmtC-2i5pO:41.8 | 3dmtC-2i5pO:51.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pkq | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEB (Spinaciaoleracea) |
PF00044(Gp_dh_N)PF02672(CP12)PF02800(Gp_dh_C) | 4 | ASN O 313TYR O 317ASN O 152TYR O 311 | NDP O 363 (-4.2A)NDP O 363 (-3.7A)NoneNone | 0.88A | 3dmtC-2pkqO:47.2 | 3dmtC-2pkqO:41.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2pkq | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEB (Spinaciaoleracea) |
PF00044(Gp_dh_N)PF02672(CP12)PF02800(Gp_dh_C) | 8 | SER O 148THR O 150ASN O 152CYH O 153HIS O 176TYR O 311ASN O 313TYR O 317 | NoneNoneNoneNoneNoneNoneNDP O 363 (-4.2A)NDP O 363 (-3.7A) | 0.61A | 3dmtC-2pkqO:47.2 | 3dmtC-2pkqO:41.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w5f | ENDO-1,4-BETA-XYLANASE Y (Ruminiclostridiumthermocellum) |
PF00331(Glyco_hydro_10)PF02018(CBM_4_9) | 4 | SER A 118THR A 159ASN A 157TYR A 119 | None | 0.99A | 3dmtC-2w5fA:undetectable | 3dmtC-2w5fA:22.10 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2x0n | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,GLYCOSOMAL (Trypanosomabrucei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 334TYR A 338ASN A 168TYR A 332 | NAD A 361 (-4.0A)NAD A 361 ( 3.8A)NoneNone | 0.97A | 3dmtC-2x0nA:50.5 | 3dmtC-2x0nA:90.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2x0n | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,GLYCOSOMAL (Trypanosomabrucei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 164THR A 166ASN A 168CYH A 169HIS A 193TYR A 332ASN A 334TYR A 338 | SO4 A 360 (-2.6A)SO4 A 360 ( 4.7A)NoneNoneNoneNoneNAD A 361 (-4.0A)NAD A 361 ( 3.8A) | 0.38A | 3dmtC-2x0nA:50.5 | 3dmtC-2x0nA:90.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xf8 | D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE (Escherichiacoli) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | SER A 148THR A 150ASN A 152CYH A 153ASN A 313 | SO4 A 500 ( 4.0A)SO4 A 500 (-3.2A)NoneNoneNone | 0.61A | 3dmtC-2xf8A:42.6 | 3dmtC-2xf8A:37.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2xf8 | D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE (Escherichiacoli) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 5 | SER A 148THR A 150ASN A 152CYH A 153HIS A 176 | SO4 A 500 ( 4.0A)SO4 A 500 (-3.2A)NoneNoneSO4 A 500 (-4.7A) | 1.01A | 3dmtC-2xf8A:42.6 | 3dmtC-2xf8A:37.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a5r | BENZALACETONESYNTHASE (Rheum palmatum) |
PF00195(Chal_sti_synt_N)PF02797(Chal_sti_synt_C) | 4 | ASN A 22CYH A 23TYR A 62ASN A 19 | None | 0.86A | 3dmtC-3a5rA:undetectable | 3dmtC-3a5rA:23.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a74 | LYSYL-TRNASYNTHETASE (Geobacillusstearothermophilus) |
PF00152(tRNA-synt_2)PF01336(tRNA_anti-codon) | 4 | SER A 478THR A 476ASN A 477TYR A 303 | None | 0.81A | 3dmtC-3a74A:undetectable | 3dmtC-3a74A:20.52 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3b20 | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE(NADP+) (Synechococcuselongatus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 318TYR A 322ASN A 158TYR A 316 | NAD A 340 (-4.2A)NAD A 340 ( 3.6A)NoneNone | 0.98A | 3dmtC-3b20A:48.9 | 3dmtC-3b20A:47.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3b20 | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE(NADP+) (Synechococcuselongatus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 154THR A 156ASN A 158CYH A 159HIS A 182TYR A 316ASN A 318TYR A 322 | SO4 A1339 (-2.7A)SO4 A1339 (-3.7A)NoneNoneNoneNoneNAD A 340 (-4.2A)NAD A 340 ( 3.6A) | 0.29A | 3dmtC-3b20A:48.9 | 3dmtC-3b20A:47.63 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3cps | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Cryptosporidiumparvum) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 334TYR A 338ASN A 171TYR A 332 | NAD A 401 (-3.6A)NAD A 401 (-3.7A)NoneNone | 0.96A | 3dmtC-3cpsA:27.9 | 3dmtC-3cpsA:50.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3cps | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Cryptosporidiumparvum) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 167THR A 169ASN A 171CYH A 172HIS A 195TYR A 332ASN A 334TYR A 338 | NoneNoneNoneNoneNoneNoneNAD A 401 (-3.6A)NAD A 401 (-3.7A) | 0.34A | 3dmtC-3cpsA:27.9 | 3dmtC-3cpsA:50.40 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3doc | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Brucellaabortus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 7 | SER A 152THR A 154ASN A 156CYH A 157HIS A 180TYR A 314ASN A 316 | NoneNoneNoneNoneNoneNoneNAD A 901 (-3.9A) | 0.41A | 3dmtC-3docA:47.7 | 3dmtC-3docA:47.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3e6a | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,CYTOSOLIC (Oryza sativa) |
no annotation | 8 | SER O 153THR O 155ASN O 157CYH O 158HIS O 181TYR O 316ASN O 318TYR O 322 | SO4 O6921 (-2.4A)SO4 O6921 (-3.9A)NoneNoneNoneNoneNoneNone | 0.49A | 3dmtC-3e6aO:47.9 | 3dmtC-3e6aO:55.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3gnq | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE, TYPEI (Burkholderiapseudomallei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 7 | SER A 153THR A 155ASN A 157CYH A 158HIS A 181TYR A 314ASN A 316 | None | 0.36A | 3dmtC-3gnqA:46.5 | 3dmtC-3gnqA:49.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hbd | CLASS IV CHITINASECHIA4-PA2 (Picea abies) |
PF00182(Glyco_hydro_19) | 4 | SER A 153TYR A 156ASN A 155TYR A 158 | ACT A 310 (-3.2A)NoneNoneNone | 1.01A | 3dmtC-3hbdA:undetectable | 3dmtC-3hbdA:19.89 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3hja | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Borreliellaburgdorferi) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 318TYR A 322ASN A 156TYR A 316 | NAD A 337 (-3.7A)NAD A 337 (-3.6A)NoneNone | 0.98A | 3dmtC-3hjaA:47.1 | 3dmtC-3hjaA:45.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3hja | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Borreliellaburgdorferi) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 152THR A 154ASN A 156CYH A 157HIS A 180TYR A 316ASN A 318TYR A 322 | SO4 A 336 (-3.2A)SO4 A 336 (-3.3A)NoneNoneSO4 A 336 (-4.4A)NoneNAD A 337 (-3.7A)NAD A 337 (-3.6A) | 0.24A | 3dmtC-3hjaA:47.1 | 3dmtC-3hjaA:45.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3k2b | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEA, CHLOROPLASTIC (Arabidopsisthaliana) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 313TYR A 317ASN A 152TYR A 311 | NAD A 335 (-3.9A)NAD A 335 (-3.5A)NoneNone | 1.02A | 3dmtC-3k2bA:48.9 | 3dmtC-3k2bA:44.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3k2b | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEA, CHLOROPLASTIC (Arabidopsisthaliana) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 148THR A 150ASN A 152CYH A 153HIS A 176TYR A 311ASN A 313TYR A 317 | SO4 A 337 (-3.1A)SO4 A 337 ( 4.2A)NoneNoneNoneNoneNAD A 335 (-3.9A)NAD A 335 (-3.5A) | 0.33A | 3dmtC-3k2bA:48.9 | 3dmtC-3k2bA:44.38 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ksd | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE1 (Staphylococcusaureus) |
no annotation | 6 | SER Q 150THR Q 152ASN Q 154TYR Q 314ASN Q 316TYR Q 320 | NoneNoneNoneNoneNAD Q 337 (-3.8A)NAD Q 337 ( 3.8A) | 0.23A | 3dmtC-3ksdQ:47.0 | 3dmtC-3ksdQ:42.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3l0d | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Bartonellahenselae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 7 | SER A 152THR A 154ASN A 156CYH A 157HIS A 180TYR A 314ASN A 316 | NoneNoneNoneNoneNoneNoneNAD A 336 (-3.9A) | 0.33A | 3dmtC-3l0dA:47.4 | 3dmtC-3l0dA:44.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3nqh | GLYCOSYL HYDROLASE (Bacteroidesthetaiotaomicron) |
PF04616(Glyco_hydro_43) | 4 | SER A 261THR A 258ASN A 260ASN A 231 | None | 0.98A | 3dmtC-3nqhA:undetectable | 3dmtC-3nqhA:22.60 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3pym | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE3 (Saccharomycescerevisiae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 314TYR A 318ASN A 153TYR A 312 | NAD A 333 (-3.7A)NAD A 333 (-3.6A)NoneNone | 0.97A | 3dmtC-3pymA:48.8 | 3dmtC-3pymA:51.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3pym | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE3 (Saccharomycescerevisiae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 149THR A 151ASN A 153CYH A 154HIS A 177TYR A 312ASN A 314TYR A 318 | NoneNoneNoneNoneNoneNoneNAD A 333 (-3.7A)NAD A 333 (-3.6A) | 0.29A | 3dmtC-3pymA:48.8 | 3dmtC-3pymA:51.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3sth | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Toxoplasmagondii) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 319TYR A 323ASN A 155TYR A 317 | NAD A 380 (-3.8A)NAD A 380 (-3.6A)NoneNone | 0.96A | 3dmtC-3sthA:49.1 | 3dmtC-3sthA:48.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3sth | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Toxoplasmagondii) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 151THR A 153ASN A 155CYH A 156HIS A 179TYR A 317ASN A 319TYR A 323 | NoneNoneNoneNoneNoneNoneNAD A 380 (-3.8A)NAD A 380 (-3.6A) | 0.28A | 3dmtC-3sthA:49.1 | 3dmtC-3sthA:48.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3zdf | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Thermosynechococcuselongatus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 317TYR A 321ASN A 157TYR A 315 | NAD A1001 (-3.7A)NAD A1001 (-3.5A)NoneNone | 0.94A | 3dmtC-3zdfA:48.9 | 3dmtC-3zdfA:47.07 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3zdf | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Thermosynechococcuselongatus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 153THR A 155ASN A 157CYH A 158HIS A 181TYR A 315ASN A 317TYR A 321 | NoneNoneNoneNoneNoneNoneNAD A1001 (-3.7A)NAD A1001 (-3.5A) | 0.27A | 3dmtC-3zdfA:48.9 | 3dmtC-3zdfA:47.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cvu | BETA-MANNOSIDASE (Trichodermaharzianum) |
PF00703(Glyco_hydro_2) | 4 | THR A 642ASN A 626HIS A 639ASN A 640 | NAG A1943 (-4.4A)NoneNoneNAG A1975 (-1.9A) | 0.94A | 3dmtC-4cvuA:undetectable | 3dmtC-4cvuA:18.26 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dib | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Bacillusanthracis) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 314TYR A 318ASN A 154TYR A 312 | None | 0.99A | 3dmtC-4dibA:43.6 | 3dmtC-4dibA:45.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dib | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Bacillusanthracis) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 7 | SER A 150THR A 152ASN A 154CYH A 155HIS A 178TYR A 312TYR A 318 | None | 0.72A | 3dmtC-4dibA:43.6 | 3dmtC-4dibA:45.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4dib | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE (Bacillusanthracis) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 7 | SER A 150THR A 152ASN A 154CYH A 155TYR A 312ASN A 314TYR A 318 | None | 0.23A | 3dmtC-4dibA:43.6 | 3dmtC-4dibA:45.08 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4gpd | APO-D-GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE (Homarusamericanus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN 1 312TYR 1 316ASN 1 151TYR 1 310 | None | 1.01A | 3dmtC-4gpd1:25.2 | 3dmtC-4gpd1:55.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4gpd | APO-D-GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE (Homarusamericanus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER 1 147THR 1 149ASN 1 151CYH 1 152HIS 1 175TYR 1 310ASN 1 312TYR 1 316 | None | 0.65A | 3dmtC-4gpd1:25.2 | 3dmtC-4gpd1:55.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4igi | COLLAGEN ALPHA3(VI) (Mus musculus) |
PF00092(VWA) | 4 | SER A1141THR A1105ASN A1104TYR A1069 | None | 0.81A | 3dmtC-4igiA:4.1 | 3dmtC-4igiA:20.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ij4 | CHITINASE A (Gemmabryumcoronatum) |
PF00182(Glyco_hydro_19) | 4 | SER A 102TYR A 105ASN A 104TYR A 107 | NAG A 303 (-3.5A)EDO A 308 (-3.6A)EDO A 307 ( 4.5A)None | 1.02A | 3dmtC-4ij4A:undetectable | 3dmtC-4ij4A:19.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4k9d | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Brugia malayi) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 321TYR A 325ASN A 160TYR A 319 | NAD A 401 (-3.9A)NAD A 401 (-3.6A)NoneNone | 0.95A | 3dmtC-4k9dA:50.0 | 3dmtC-4k9dA:52.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4k9d | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Brugia malayi) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 156THR A 158ASN A 160CYH A 161HIS A 184TYR A 319ASN A 321TYR A 325 | NoneNoneNoneNoneNoneNoneNAD A 401 (-3.9A)NAD A 401 (-3.6A) | 0.27A | 3dmtC-4k9dA:50.0 | 3dmtC-4k9dA:52.04 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lsm | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE,CYTOSOLIC (Trypanosomacruzi) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 320TYR A 324ASN A 159TYR A 318 | NAD A 401 (-3.7A)NAD A 401 (-3.6A)NoneNone | 0.92A | 3dmtC-4lsmA:49.3 | 3dmtC-4lsmA:49.87 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4lsm | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE,CYTOSOLIC (Trypanosomacruzi) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 155THR A 157ASN A 159CYH A 160HIS A 183TYR A 318ASN A 320TYR A 324 | NoneNoneNoneNoneNoneNoneNAD A 401 (-3.7A)NAD A 401 (-3.6A) | 0.30A | 3dmtC-4lsmA:49.3 | 3dmtC-4lsmA:49.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mst | CLASS I CHITINASE (Heveabrasiliensis) |
PF00182(Glyco_hydro_19) | 4 | SER A 170TYR A 173ASN A 172TYR A 175 | None | 1.01A | 3dmtC-4mstA:undetectable | 3dmtC-4mstA:18.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4nqf | NUCLEOTIDYLTRANSFERASE (Agrobacteriumfabrum) |
PF05168(HEPN) | 4 | SER A 213HIS A 163ASN A 211TYR A 212 | None | 0.78A | 3dmtC-4nqfA:undetectable | 3dmtC-4nqfA:17.70 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4o59 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Bos taurus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN O 313TYR O 317ASN O 152TYR O 311 | NAD O 401 (-3.8A)NAD O 401 (-3.5A)NoneNone | 0.96A | 3dmtC-4o59O:48.8 | 3dmtC-4o59O:52.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4o59 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Bos taurus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER O 148THR O 150ASN O 152CYH O 153HIS O 176TYR O 311ASN O 313TYR O 317 | NoneNoneNoneNoneNoneNoneNAD O 401 (-3.8A)NAD O 401 (-3.5A) | 0.30A | 3dmtC-4o59O:48.8 | 3dmtC-4o59O:52.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p8r | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE,CYTOSOLIC (Trypanosomabrucei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN A 314TYR A 318ASN A 153TYR A 312 | NAD A 400 (-3.7A)NAD A 400 (-3.6A)NoneNone | 0.96A | 3dmtC-4p8rA:48.8 | 3dmtC-4p8rA:51.25 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4p8r | GLYCERALDEHYDE3-PHOSPHATEDEHYDROGENASE,CYTOSOLIC (Trypanosomabrucei) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 149THR A 151ASN A 153CYH A 154HIS A 177TYR A 312ASN A 314TYR A 318 | NoneNoneNoneNoneNoneNoneNAD A 400 (-3.7A)NAD A 400 (-3.6A) | 0.31A | 3dmtC-4p8rA:48.8 | 3dmtC-4p8rA:51.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pu5 | TOXIN-ANTITOXINSYSTEM TOXIN HIPAFAMILY (Shewanellaoneidensis) |
PF07804(HipA_C)PF13657(Couple_hipA) | 4 | SER A 313CYH A 242ASN A 311TYR A 312 | ANP A 503 ( 4.2A)None MG A 502 ( 2.5A)None | 1.00A | 3dmtC-4pu5A:undetectable | 3dmtC-4pu5A:25.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4q4y | COXSACKIEVIRUSCAPSID PROTEIN VP2 (Enterovirus C) |
PF00073(Rhv) | 4 | SER 2 164THR 2 136ASN 2 135CYH 2 134 | None | 0.96A | 3dmtC-4q4y2:undetectable | 3dmtC-4q4y2:19.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4x6k | ANHYDROSIALIDASE ([Ruminococcus]gnavus) |
PF13088(BNR_2) | 4 | SER A 411THR A 409ASN A 410TYR A 405 | None | 0.99A | 3dmtC-4x6kA:undetectable | 3dmtC-4x6kA:21.91 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4z0h | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEGAPC1, CYTOSOLIC (Arabidopsisthaliana) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN O 313TYR O 317ASN O 152TYR O 311 | NAD O 401 (-3.8A)NAD O 401 (-3.7A)NoneNone | 0.95A | 3dmtC-4z0hO:48.5 | 3dmtC-4z0hO:55.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4z0h | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASEGAPC1, CYTOSOLIC (Arabidopsisthaliana) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER O 148THR O 150ASN O 152CYH O 153HIS O 176TYR O 311ASN O 313TYR O 317 | SO4 O 403 (-2.8A)SO4 O 403 (-4.0A)NoneNoneNoneNoneNAD O 401 (-3.8A)NAD O 401 (-3.7A) | 0.25A | 3dmtC-4z0hO:48.5 | 3dmtC-4z0hO:55.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5c7i | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,TESTIS-SPECIFIC (Mus musculus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN O 420TYR O 424ASN O 259TYR O 418 | None | 0.97A | 3dmtC-5c7iO:48.6 | 3dmtC-5c7iO:51.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5c7i | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,TESTIS-SPECIFIC (Mus musculus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER O 255THR O 257ASN O 259CYH O 260HIS O 283TYR O 418ASN O 420TYR O 424 | None | 0.35A | 3dmtC-5c7iO:48.6 | 3dmtC-5c7iO:51.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5c7o | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,TESTIS-SPECIFIC (Homo sapiens) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 4 | ASN O 388TYR O 392ASN O 227TYR O 386 | NAD O 501 (-3.9A)NAD O 501 (-2.7A)OCS O 224 ( 4.8A)OCS O 224 ( 4.0A) | 0.94A | 3dmtC-5c7oO:49.8 | 3dmtC-5c7oO:52.96 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5c7o | GLYCERALDEHYDE-3-PHOSPHATEDEHYDROGENASE,TESTIS-SPECIFIC (Homo sapiens) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER O 223THR O 225ASN O 227CYH O 228HIS O 251TYR O 386ASN O 388TYR O 392 | OCS O 224 ( 3.4A)OCS O 224 ( 4.2A)OCS O 224 ( 4.8A)NoneOCS O 224 ( 3.9A)OCS O 224 ( 4.0A)NAD O 501 (-3.9A)NAD O 501 (-2.7A) | 0.24A | 3dmtC-5c7oO:49.8 | 3dmtC-5c7oO:52.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cyf | PUTATIVE URIDINEPHOSPHORYLASE (Schistosomamansoni) |
PF01048(PNP_UDP_1) | 4 | THR A 239ASN A 243CYH A 242ASN A 150 | None | 0.97A | 3dmtC-5cyfA:2.1 | 3dmtC-5cyfA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5h7t | CLASS IV CHITINASE (Cryptomeriajaponica) |
no annotation | 4 | SER A 107TYR A 110ASN A 109TYR A 112 | None | 0.86A | 3dmtC-5h7tA:undetectable | 3dmtC-5h7tA:19.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hj2 | INTEGRIN ALPHA-2 (Homo sapiens) |
no annotation | 4 | SER C 121THR C 87ASN C 86TYR C 51 | None | 0.89A | 3dmtC-5hj2C:4.4 | 3dmtC-5hj2C:21.82 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5j9g | GLYCERALDEHYDE-3-PDEHYDROGENASE (Lactobacillusacidophilus) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 6 | SER A 155THR A 157ASN A 159HIS A 183TYR A 318ASN A 320 | None | 0.40A | 3dmtC-5j9gA:45.2 | 3dmtC-5j9gA:41.27 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5ld5 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Atopobiumvaginae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 167THR A 169ASN A 171CYH A 172HIS A 195TYR A 334ASN A 336TYR A 340 | GOL A 404 (-3.0A)GOL A 404 ( 4.8A)NoneNoneNoneNoneNAD A 401 (-4.1A)NAD A 401 (-3.8A) | 0.35A | 3dmtC-5ld5A:44.4 | 3dmtC-5ld5A:41.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5the | UNCHARACTERIZEDPROTEIN (Vanderwaltozymapolyspora) |
no annotation | 4 | SER A1143ASN A1175CYH A1174TYR A1156 | None | 0.95A | 3dmtC-5theA:3.9 | 3dmtC-5theA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur0 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Naegleriagruberi) |
no annotation | 4 | ASN A 314TYR A 318ASN A 152TYR A 312 | NAD A 401 (-3.7A)NAD A 401 (-3.5A)NoneOCS A 149 ( 4.1A) | 0.94A | 3dmtC-5ur0A:49.7 | 3dmtC-5ur0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ur0 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Naegleriagruberi) |
no annotation | 8 | SER A 148THR A 150ASN A 152CYH A 153HIS A 176TYR A 312ASN A 314TYR A 318 | OCS A 149 ( 3.5A)OCS A 149 ( 3.8A)NoneNoneOCS A 149 ( 4.0A)OCS A 149 ( 4.1A)NAD A 401 (-3.7A)NAD A 401 (-3.5A) | 0.24A | 3dmtC-5ur0A:49.7 | 3dmtC-5ur0A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vha | DEAH(ASP-GLU-ALA-HIS)BOX POLYPEPTIDE 36 (Bos taurus) |
no annotation | 4 | SER A 291THR A 292ASN A 290CYH A 286 | None | 0.90A | 3dmtC-5vhaA:2.2 | 3dmtC-5vhaA:undetectable | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5vmt | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Neisseriagonorrhoeae) |
PF00044(Gp_dh_N)PF02800(Gp_dh_C) | 8 | SER A 150THR A 152ASN A 154CYH A 155HIS A 178TYR A 313ASN A 315TYR A 319 | NoneNoneNoneNoneNoneNoneNAD A 401 (-3.7A)NAD A 401 (-3.5A) | 0.38A | 3dmtC-5vmtA:47.2 | 3dmtC-5vmtA:44.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y37 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Streptococcusagalactiae) |
no annotation | 4 | ASN A 320TYR A 324ASN A 159TYR A 318 | NAD A 401 (-3.7A)NAD A 401 (-3.6A)NoneNone | 1.00A | 3dmtC-5y37A:46.7 | 3dmtC-5y37A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y37 | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Streptococcusagalactiae) |
no annotation | 8 | SER A 155THR A 157ASN A 159CYH A 160HIS A 183TYR A 318ASN A 320TYR A 324 | NoneNoneNoneNoneNoneNoneNAD A 401 (-3.7A)NAD A 401 (-3.6A) | 0.36A | 3dmtC-5y37A:46.7 | 3dmtC-5y37A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dfz | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Acroporamillepora) |
no annotation | 4 | ASN A 315TYR A 319ASN A 154TYR A 313 | NAD A 401 (-4.0A)NAD A 401 (-3.6A)NoneNone | 0.99A | 3dmtC-6dfzA:27.4 | 3dmtC-6dfzA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6dfz | GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Acroporamillepora) |
no annotation | 8 | SER A 150THR A 152ASN A 154CYH A 155HIS A 178TYR A 313ASN A 315TYR A 319 | PO4 A 402 (-2.7A)PO4 A 402 (-3.1A)NoneNonePO4 A 402 (-4.0A)NoneNAD A 401 (-4.0A)NAD A 401 (-3.6A) | 0.23A | 3dmtC-6dfzA:27.4 | 3dmtC-6dfzA:undetectable |