SIMILAR PATTERNS OF AMINO ACIDS FOR 3DGQ_A_EAAA211

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
16vp PROTEIN (VP16,
VMW65, ATIF)

(Human
alphaherpesvirus
1) 		PF02232
(Alpha_TIF) 		4 ARG A 129
ILE A 128
TYR A 168
THR A 170
 None
 1.25A 3dgqA-16vpA:
0.0		 3dgqA-16vpA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fxl PARANEOPLASTIC
ENCEPHALOMYELITIS
ANTIGEN HUD

(Homo sapiens) 		PF00076
(RRM_1) 		4 ARG A  56
ILE A  65
TYR A  87
THR A  39
 None
 1.28A 3dgqA-1fxlA:
0.0		 3dgqA-1fxlA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1h4u NIDOGEN-1

(Mus musculus) 		PF07474
(G2F) 		4 TYR A 577
ILE A 460
TYR A 621
THR A 441
 None
 1.31A 3dgqA-1h4uA:
undetectable		 3dgqA-1h4uA:
21.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1lbk GLUTATHIONE
S-TRANSFERASE CLASS
PI CHIMAERA (CODA)

(Homo sapiens) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		5 TYR A   7
ARG A  13
ILE A 104
TYR A 108
THR A 109
 None
GSH  A 504 (-3.7A)
None
None
None
 0.58A 3dgqA-1lbkA:
36.0		 3dgqA-1lbkA:
97.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1s4k PUTATIVE CYTOPLASMIC
PROTEIN YDIL

(Salmonella
enterica) 		PF08965
(DUF1870) 		4 ARG A  80
ILE A  91
TYR A  92
THR A  93
 None
 1.44A 3dgqA-1s4kA:
0.0		 3dgqA-1s4kA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1t8q GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE,
PERIPLASMIC

(Escherichia
coli) 		PF03009
(GDPD) 		4 TYR A 273
ILE A 236
TYR A 258
THR A 239
 None
 1.46A 3dgqA-1t8qA:
0.0		 3dgqA-1t8qA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wcd MAJOR STRUCTURAL
PROTEIN VP2

(Infectious
bursal disease
virus) 		PF01766
(Birna_VP2) 		4 TYR J 342
ARG J 100
ILE J  28
THR J 398
 None
 1.19A 3dgqA-1wcdJ:
undetectable		 3dgqA-1wcdJ:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xzq PROBABLE TRNA
MODIFICATION GTPASE
TRME

(Thermotoga
maritima) 		PF01926
(MMR_HSR1)
PF10396
(TrmE_N)
PF12631
(MnmE_helical) 		4 TYR B  65
ARG B  20
ILE A  16
THR A   9
 None
FON  B 118 (-4.5A)
FON  B 118 (-4.3A)
None
 1.15A 3dgqA-1xzqB:
0.0		 3dgqA-1xzqB:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zpu IRON TRANSPORT
MULTICOPPER OXIDASE
FET3

(Saccharomyces
cerevisiae) 		PF00394
(Cu-oxidase)
PF07731
(Cu-oxidase_2)
PF07732
(Cu-oxidase_3) 		4 TYR A 461
ILE A 236
TYR A 257
THR A 258
 None
 1.26A 3dgqA-1zpuA:
undetectable		 3dgqA-1zpuA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zsq MYOTUBULARIN-RELATED
PROTEIN 2

(Homo sapiens) 		PF02893
(GRAM)
PF06602
(Myotub-related) 		4 TYR A 371
ILE A  94
TYR A  93
THR A  92
 None
 1.45A 3dgqA-1zsqA:
undetectable		 3dgqA-1zsqA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2dw4 LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM) 		4 ARG A 820
ILE A 804
TYR A 807
THR A 810
 None
None
None
FAD  A1001 (-4.3A)
 1.43A 3dgqA-2dw4A:
undetectable		 3dgqA-2dw4A:
16.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gsr CLASS PI GST
GLUTATHIONE
S-TRANSFERASE

(Sus scrofa) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
ARG A  13
TYR A 106
THR A 107
 GTS  A 208 (-4.5A)
GTS  A 208 (-4.0A)
None
None
 0.23A 3dgqA-2gsrA:
35.6		 3dgqA-2gsrA:
82.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j42 C2 TOXIN
COMPONENT-II

(Clostridium
botulinum) 		PF03495
(Binary_toxB)
PF07691
(PA14)
PF17475
(Binary_toxB_2)
PF17476
(Binary_toxB_3) 		4 TYR A 377
ILE A 248
TYR A 238
THR A 239
 None
 1.34A 3dgqA-2j42A:
undetectable		 3dgqA-2j42A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2jx2 NEGATIVE ELONGATION
FACTOR E

(Homo sapiens) 		PF00076
(RRM_1) 		4 ARG A  55
ILE A  64
TYR A  80
THR A  41
 None
 1.30A 3dgqA-2jx2A:
undetectable		 3dgqA-2jx2A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pok PEPTIDASE,
M20/M25/M40 FAMILY

(Streptococcus
pneumoniae) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 ARG A  55
ILE A  52
TYR A  22
THR A 129
 None
 1.05A 3dgqA-2pokA:
undetectable		 3dgqA-2pokA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ahm OLIGOPEPTIDASE

(Geobacillus sp.
MO-1) 		no annotation 4 TYR A 467
ARG A 476
TYR A 481
THR A 482
 None
 1.01A 3dgqA-3ahmA:
2.0		 3dgqA-3ahmA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3al9 PLEXIN-A2

(Mus musculus) 		PF01403
(Sema)
PF01437
(PSI) 		4 TYR A 293
ILE A 241
TYR A 243
THR A 167
 None
 1.30A 3dgqA-3al9A:
undetectable		 3dgqA-3al9A:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3byw PUTATIVE
ARABINOFURANOSYLTRAN
SFERASE

(Corynebacterium
diphtheriae) 		PF04602
(Arabinose_trans) 		4 TYR A  60
ILE A 169
TYR A 170
THR A 171
 None
 1.42A 3dgqA-3bywA:
undetectable		 3dgqA-3bywA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3c1o EUGENOL SYNTHASE

(Clarkia breweri) 		PF05368
(NmrA) 		4 ARG A 117
ILE A 209
TYR A 147
THR A 146
 None
 1.26A 3dgqA-3c1oA:
undetectable		 3dgqA-3c1oA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3h51 PUTATIVE
CALCIUM/CALMODULIN
DEPENDENT PROTEIN
KINASE II
ASSOCIATION DOMAIN

(Xanthomonas
campestris) 		PF08332
(CaMKII_AD) 		4 ARG A 103
ILE A 100
TYR A 119
THR A 120
 None
 1.28A 3dgqA-3h51A:
undetectable		 3dgqA-3h51A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hsi PHOSPHATIDYLSERINE
SYNTHASE

(Haemophilus
influenzae) 		PF13091
(PLDc_2) 		4 TYR A 172
ARG A 171
ILE A 412
THR A 416
 None
 1.30A 3dgqA-3hsiA:
undetectable		 3dgqA-3hsiA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jb9 PRE-MRNA-SPLICING
FACTOR SPP42

(Schizosaccharomyces
pombe) 		PF08082
(PRO8NT)
PF08083
(PROCN)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 TYR A1114
ARG A1461
TYR A1297
THR A1296
 None
 0.98A 3dgqA-3jb9A:
undetectable		 3dgqA-3jb9A:
6.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8p DSL1

(Kluyveromyces
lactis) 		PF11989
(Dsl1_C) 		4 TYR C 558
ILE C 570
TYR C 618
THR C 617
 None
 1.47A 3dgqA-3k8pC:
undetectable		 3dgqA-3k8pC:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kx2 PRE-MRNA-SPLICING
FACTOR ATP-DEPENDENT
RNA HELICASE PRP43

(Saccharomyces
cerevisiae) 		no annotation 4 ARG B 159
ILE B  86
TYR B  83
THR B  80
 ADP  B1000 (-3.6A)
None
None
None
 1.32A 3dgqA-3kx2B:
undetectable		 3dgqA-3kx2B:
15.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus musculus) 		PF02798
(GST_N)
PF14497
(GST_C_3) 		4 TYR A   7
ARG A  13
TYR A 108
THR A 109
 None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
None
 0.17A 3dgqA-3o76A:
36.4		 3dgqA-3o76A:
84.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3oky PLEXIN-A2

(Mus musculus) 		PF01403
(Sema)
PF01437
(PSI) 		4 TYR A 293
ILE A 241
TYR A 243
THR A 167
 None
 1.24A 3dgqA-3okyA:
undetectable		 3dgqA-3okyA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p0s CAPSID PROTEIN VP

(Lepidopteran
iteradensovirus
1) 		PF01057
(Parvo_NS1) 		4 TYR A 349
ARG A 423
ILE A 427
THR A 285
 None
 1.49A 3dgqA-3p0sA:
undetectable		 3dgqA-3p0sA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vxi DYP

(Bjerkandera
adusta) 		PF04261
(Dyp_perox) 		4 TYR A 427
ARG A 368
ILE A 372
THR A 397
 None
 1.25A 3dgqA-3vxiA:
undetectable		 3dgqA-3vxiA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3wwt PROTEIN C'

(Murine
respirovirus) 		PF01692
(Paramyxo_C) 		4 ARG B 157
ILE B 104
TYR B 108
THR B 109
 None
 0.99A 3dgqA-3wwtB:
undetectable		 3dgqA-3wwtB:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3zef PRE-MRNA-SPLICING
FACTOR 8

(Saccharomyces
cerevisiae) 		PF08084
(PROCT)
PF10596
(U6-snRNA_bdg)
PF10597
(U5_2-snRNA_bdg)
PF10598
(RRM_4)
PF12134
(PRP8_domainIV) 		4 TYR B1164
ARG B1509
TYR B1345
THR B1344
 None
 1.12A 3dgqA-3zefB:
undetectable		 3dgqA-3zefB:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bfe CELL SURFACE
GLYCOPROTEIN CD200
RECEPTOR 4

(Mus musculus) 		PF07686
(V-set)
PF08205
(C2-set_2) 		4 ARG A  76
ILE A  50
TYR A 103
THR A 104
 None
 1.33A 3dgqA-4bfeA:
undetectable		 3dgqA-4bfeA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bfg CELL SURFACE
GLYCOPROTEIN CD200
RECEPTOR 1

(Mus musculus) 		PF07686
(V-set)
PF08205
(C2-set_2) 		4 ARG A  76
ILE A  50
TYR A 103
THR A 104
 None
 1.29A 3dgqA-4bfgA:
undetectable		 3dgqA-4bfgA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d10 COP9 SIGNALOSOME
COMPLEX SUBUNIT 8

(Homo sapiens) 		PF10075
(CSN8_PSD8_EIF3K) 		4 ARG H 116
ILE H  89
TYR H  90
THR H  91
 None
 1.39A 3dgqA-4d10H:
undetectable		 3dgqA-4d10H:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4grv NEUROTENSIN RECEPTOR
TYPE 1, LYSOZYME
CHIMERA

(Escherichia
virus T4;
Rattus
norvegicus) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme) 		4 TYR A 347
ARG A 328
ILE A 238
THR A 233
 None
 1.25A 3dgqA-4grvA:
undetectable		 3dgqA-4grvA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jlc SERINE/THREONINE-PRO
TEIN KINASE TBK1

(Mus musculus) 		PF00069
(Pkinase) 		4 ARG A 525
ILE A 522
TYR A 454
THR A 457
 None
 1.46A 3dgqA-4jlcA:
undetectable		 3dgqA-4jlcA:
14.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4k7g 3-HYDROXYPROLINE
DEHYDRATSE

(Agrobacterium
vitis) 		PF05544
(Pro_racemase) 		4 ARG B 282
ILE B 280
TYR B 279
THR B 278
 None
 1.38A 3dgqA-4k7gB:
undetectable		 3dgqA-4k7gB:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l39 4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12

(Arabidopsis
thaliana) 		PF03321
(GH3) 		4 TYR A 120
ILE A 188
TYR A 181
THR A 182
 SAL  A 602 (-4.3A)
None
None
None
 1.48A 3dgqA-4l39A:
undetectable		 3dgqA-4l39A:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p6q MSX2-INTERACTING
PROTEIN

(Homo sapiens) 		PF00076
(RRM_1) 		4 ARG A 455
ILE A 464
TYR A 483
THR A 439
 None
 1.43A 3dgqA-4p6qA:
undetectable		 3dgqA-4p6qA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydo UNCHARACTERIZED
PROTEIN

(Candida
albicans) 		PF00432
(Prenyltrans) 		4 TYR B 373
ILE B 559
TYR B 199
THR B 264
 None
 1.42A 3dgqA-4ydoB:
2.2		 3dgqA-4ydoB:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5bn4 NEQ263

(Nanoarchaeum
equitans) 		PF00006
(ATP-synt_ab) 		4 TYR B  69
ILE B  94
TYR B  61
THR B  60
 None
 1.40A 3dgqA-5bn4B:
undetectable		 3dgqA-5bn4B:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e5d PEPTIDE DEFORMYLASE

(Xanthomonas
oryzae) 		PF01327
(Pep_deformylase) 		4 TYR A  69
ARG A 137
ILE A 109
TYR A 151
 None
 1.12A 3dgqA-5e5dA:
undetectable		 3dgqA-5e5dA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e66 HEMAGGLUTININ-ESTERA
SE

(Influenza D
virus) 		PF02710
(Hema_HEFG)
PF03996
(Hema_esterase) 		4 TYR A 101
ARG A  81
ILE A  52
THR A 150
 None
 0.94A 3dgqA-5e66A:
undetectable		 3dgqA-5e66A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fbh EXTRACELLULAR
CALCIUM-SENSING
RECEPTOR

(Homo sapiens) 		no annotation 4 ARG B  66
ILE B 416
TYR B 167
THR B 186
 TCR  B 609 ( 3.6A)
BCT  B 604 (-4.5A)
None
None
 1.49A 3dgqA-5fbhB:
undetectable		 3dgqA-5fbhB:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gz4 SNAKE VENOM
PHOSPHODIESTERASE
(PDE)

(Naja atra) 		PF01033
(Somatomedin_B)
PF01223
(Endonuclease_NS)
PF01663
(Phosphodiest) 		4 TYR A 756
ILE A 750
TYR A 658
THR A 654
 None
 1.37A 3dgqA-5gz4A:
undetectable		 3dgqA-5gz4A:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h42 UNCHARACTERIZED
PROTEIN

(Lachnoclostridium
phytofermentans) 		PF17167
(Glyco_hydro_36) 		4 ARG A 743
ILE A 751
TYR A 744
THR A 748
 None
 1.22A 3dgqA-5h42A:
undetectable		 3dgqA-5h42A:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i51 TRANSKETOLASE

(Scheffersomyces
stipitis) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 ARG A 407
ILE A 373
TYR A 435
THR A 461
 None
 1.41A 3dgqA-5i51A:
undetectable		 3dgqA-5i51A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l3d LYSINE-SPECIFIC
HISTONE DEMETHYLASE
1A

(Homo sapiens) 		PF01593
(Amino_oxidase)
PF04433
(SWIRM) 		4 ARG A 820
ILE A 804
TYR A 807
THR A 810
 None
None
None
FAD  A 901 (-4.2A)
 1.48A 3dgqA-5l3dA:
undetectable		 3dgqA-5l3dA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l5g PLEXIN-A2

(Mus musculus) 		PF01403
(Sema)
PF01437
(PSI)
PF01833
(TIG) 		4 TYR A 293
ILE A 241
TYR A 243
THR A 167
 None
 1.34A 3dgqA-5l5gA:
undetectable		 3dgqA-5l5gA:
11.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mc5 XAA-PRO DIPEPTIDASE

(Homo sapiens) 		no annotation 4 ARG A 450
ILE A 244
TYR A 241
THR A 242
 PRO  A 504 (-3.7A)
None
GLY  A 503 ( 3.6A)
None
 1.31A 3dgqA-5mc5A:
undetectable		 3dgqA-5mc5A:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ndz LYSOZYME,PROTEINASE-
ACTIVATED RECEPTOR
2,SOLUBLE CYTOCHROME
B562,PROTEINASE-ACTI
VATED RECEPTOR 2

(Escherichia
coli;
Escherichia
virus T4;
Homo sapiens) 		PF00001
(7tm_1)
PF00959
(Phage_lysozyme)
PF07361
(Cytochrom_B562) 		4 TYR A 326
ILE A 152
TYR A 156
THR A 206
 None
 1.47A 3dgqA-5ndzA:
1.0		 3dgqA-5ndzA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uj1 DNA TOPOISOMERASE 1

(Mycobacterium
tuberculosis) 		no annotation 4 TYR A 580
ILE A 203
TYR A 517
THR A 518
 None
 1.44A 3dgqA-5uj1A:
undetectable		 3dgqA-5uj1A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xmd EPOXIDE HYDROLASE A

(Vigna radiata) 		no annotation 4 TYR A 232
ARG A  60
ILE A  14
THR A   8
 None
 1.46A 3dgqA-5xmdA:
undetectable		 3dgqA-5xmdA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fb3 TENEURIN-2

(Gallus gallus) 		no annotation 4 TYR A2105
ILE A2131
TYR A2119
THR A2120
 None
 1.19A 3dgqA-6fb3A:
undetectable		 3dgqA-6fb3A:
18.45