SIMILAR PATTERNS OF AMINO ACIDS FOR 3DEU_B_SALB306_1
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1aye | PROCARBOXYPEPTIDASEA2 (Homo sapiens) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 4 | THR A 289THR A 293LEU A 195THR A 78 | None | 0.73A | 3deuB-1ayeA:1.4 | 3deuB-1ayeA:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cwu | ENOYL ACP REDUCTASE (Brassica napus) |
PF13561(adh_short_C2) | 4 | THR A 288THR A 230LEU A 209THR A 187 | None | 0.96A | 3deuB-1cwuA:0.0 | 3deuB-1cwuA:18.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1dtd | CARBOXYPEPTIDASE A2 (Homo sapiens) |
PF00246(Peptidase_M14) | 4 | THR A 645THR A 649LEU A 551THR A 433 | None | 0.73A | 3deuB-1dtdA:0.0 | 3deuB-1dtdA:21.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fc9 | PHOTOSYSTEM II D1PROTEASE (Tetradesmusobliquus) |
PF03572(Peptidase_S41)PF13180(PDZ_2) | 4 | THR A 289ILE A 312SER A 374LEU A 377 | None | 0.89A | 3deuB-1fc9A:undetectable | 3deuB-1fc9A:16.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g6o | CAG-ALPHA (Helicobacterpylori) |
PF00437(T2SSE) | 4 | THR A 270THR A 268ILE A 310LEU A 261 | None | 0.78A | 3deuB-1g6oA:0.0 | 3deuB-1g6oA:19.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1hs7 | SYNTAXIN VAM3 (Saccharomycescerevisiae) |
PF14523(Syntaxin_2) | 4 | THR A 27ILE A 85SER A 92LEU A 91 | None | 0.94A | 3deuB-1hs7A:undetectable | 3deuB-1hs7A:18.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1iip | CYCLOPHILIN 40 (Bos taurus) |
PF00160(Pro_isomerase)PF13176(TPR_7) | 4 | THR A 139SER A 119LEU A 117THR A 135 | None | 0.88A | 3deuB-1iipA:undetectable | 3deuB-1iipA:17.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jsd | HAEMAGGLUTININ (HA1CHAIN) (Influenza Avirus) |
PF00509(Hemagglutinin) | 4 | THR A 261ILE A 51SER A 265LEU A 41 | None | 0.88A | 3deuB-1jsdA:undetectable | 3deuB-1jsdA:18.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k27 | 5'-DEOXY-5'-METHYLTHIOADENOSINEPHOSPHORYLASE (Homo sapiens) |
PF01048(PNP_UDP_1) | 4 | THR A 155SER A 249LEU A 250THR A 253 | None | 0.94A | 3deuB-1k27A:undetectable | 3deuB-1k27A:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1k32 | TRICORN PROTEASE (Thermoplasmaacidophilum) |
PF03572(Peptidase_S41)PF07676(PD40)PF14684(Tricorn_C1)PF14685(Tricorn_PDZ) | 4 | THR A1004ILE A 735SER A 732LEU A 731 | None | 0.87A | 3deuB-1k32A:0.0 | 3deuB-1k32A:9.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kzl | RIBOFLAVIN SYNTHASE (Schizosaccharomycespombe) |
PF00677(Lum_binding) | 4 | THR A 47ILE A 63LEU A 73THR A 71 | CRM A 502 (-4.0A)CRM A 502 (-4.6A)NoneNone | 0.72A | 3deuB-1kzlA:undetectable | 3deuB-1kzlA:22.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nhw | ENOYL-ACYL CARRIERREDUCTASE (Plasmodiumfalciparum) |
PF13561(adh_short_C2) | 4 | THR C 410THR A 309LEU A 288THR A 266 | None | 0.97A | 3deuB-1nhwC:undetectable | 3deuB-1nhwC:16.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p1m | HYPOTHETICAL PROTEINTM0936 (Thermotogamaritima) |
PF01979(Amidohydro_1) | 4 | THR A 56ILE A 108LEU A 289THR A 278 | None | 0.77A | 3deuB-1p1mA:2.1 | 3deuB-1p1mA:15.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1rlj | NRDI PROTEIN (Bacillussubtilis) |
PF07972(Flavodoxin_NdrI) | 4 | THR A 42ILE A 87LEU A 58THR A 54 | None | 0.97A | 3deuB-1rljA:undetectable | 3deuB-1rljA:19.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xc6 | BETA-GALACTOSIDASE (Penicillium sp.) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | THR A 478ILE A 459LEU A 457THR A 452 | NoneNoneEDO A9081 (-4.5A)None | 0.72A | 3deuB-1xc6A:undetectable | 3deuB-1xc6A:9.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zi0 | DNA GYRASE SUBUNIT A (Escherichiacoli) |
PF03989(DNA_gyraseA_C) | 4 | THR A 654THR A 650ILE A 674LEU A 676 | None | 0.93A | 3deuB-1zi0A:undetectable | 3deuB-1zi0A:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1zmf | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEE (Homo sapiens) |
PF00160(Pro_isomerase) | 4 | THR A 255SER A 235LEU A 233THR A 251 | None | 0.88A | 3deuB-1zmfA:undetectable | 3deuB-1zmfA:18.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2afb | 2-KETO-3-DEOXYGLUCONATE KINASE (Thermotogamaritima) |
PF00294(PfkB) | 4 | THR A 160ILE A 287SER A 290LEU A 291 | None | 0.88A | 3deuB-2afbA:undetectable | 3deuB-2afbA:19.03 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2boa | CARBOXYPEPTIDASE A4 (Homo sapiens) |
PF00246(Peptidase_M14)PF02244(Propep_M14) | 4 | THR A1289THR A1293LEU A1195THR A1078 | None | 0.63A | 3deuB-2boaA:1.3 | 3deuB-2boaA:16.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cfe | ALLERGEN (Malasseziasympodialis) |
PF00160(Pro_isomerase) | 4 | THR A 117SER A 97LEU A 95THR A 113 | NoneNoneGOL A1163 ( 4.7A)None | 0.83A | 3deuB-2cfeA:undetectable | 3deuB-2cfeA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2exr | CYTOKININDEHYDROGENASE 7 (Arabidopsisthaliana) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | THR A 167ILE A 228SER A 173LEU A 172 | FAD A 525 (-3.1A)FAD A 525 (-4.0A)FAD A 525 (-3.1A)None | 0.96A | 3deuB-2exrA:undetectable | 3deuB-2exrA:13.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2g7z | CONSERVEDHYPOTHETICAL PROTEINSPY1493 (Streptococcuspyogenes) |
PF02645(DegV) | 4 | THR A 25ILE A 85LEU A 77THR A 73 | None | 0.88A | 3deuB-2g7zA:undetectable | 3deuB-2g7zA:19.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gwn | DIHYDROOROTASE (Porphyromonasgingivalis) |
PF01979(Amidohydro_1) | 4 | THR A 261ILE A 309LEU A 368THR A 255 | None | 0.94A | 3deuB-2gwnA:undetectable | 3deuB-2gwnA:16.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hi9 | PLASMA SERINEPROTEASE INHIBITOR (Homo sapiens) |
PF00079(Serpin) | 4 | THR A 116ILE A 317LEU A 122THR A 138 | None | 0.83A | 3deuB-2hi9A:undetectable | 3deuB-2hi9A:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nmp | CYSTATHIONINEGAMMA-LYASE (Homo sapiens) |
PF01053(Cys_Met_Meta_PP) | 4 | THR A 98ILE A 132SER A 126LEU A 130 | None | 0.88A | 3deuB-2nmpA:undetectable | 3deuB-2nmpA:19.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pcu | CARBOXYPEPTIDASE A4 (Homo sapiens) |
PF00246(Peptidase_M14) | 4 | THR A 289THR A 293LEU A 195THR A 78 | None | 0.65A | 3deuB-2pcuA:1.5 | 3deuB-2pcuA:19.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qdx | FERREDOXIN REDUCTASE (Pseudomonasaeruginosa) |
PF00175(NAD_binding_1)PF00970(FAD_binding_6) | 4 | THR A 192ILE A 218SER A 229LEU A 232 | None | 0.94A | 3deuB-2qdxA:undetectable | 3deuB-2qdxA:21.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qv3 | VACUOLATINGCYTOTOXIN (Helicobacterpylori) |
PF02691(VacA) | 4 | THR A 502THR A 478LEU A 486THR A 505 | None | 0.77A | 3deuB-2qv3A:undetectable | 3deuB-2qv3A:16.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uv8 | FATTY ACID SYNTHASESUBUNIT BETA (FAS1) (Saccharomycescerevisiae) |
PF00698(Acyl_transf_1)PF01575(MaoC_dehydratas)PF08354(DUF1729)PF13452(MaoC_dehydrat_N)PF16073(SAT) | 4 | ILE G 483SER G 274LEU G 277THR G 462 | None | 0.94A | 3deuB-2uv8G:undetectable | 3deuB-2uv8G:5.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vbf | BRANCHED-CHAINALPHA-KETOACIDDECARBOXYLASE (Lactococcuslactis) |
PF00205(TPP_enzyme_M)PF02775(TPP_enzyme_C)PF02776(TPP_enzyme_N) | 4 | ILE A 427SER A 431LEU A 432THR A 435 | ILE A 427 ( 0.7A)SER A 431 (-0.0A)LEU A 432 ( 0.5A)THR A 435 ( 0.8A) | 0.86A | 3deuB-2vbfA:undetectable | 3deuB-2vbfA:14.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vhl | N-ACETYLGLUCOSAMINE-6-PHOSPHATEDEACETYLASE (Bacillussubtilis) |
PF01979(Amidohydro_1) | 4 | THR A 332ILE A 342SER A 273LEU A 276 | None | 0.92A | 3deuB-2vhlA:undetectable | 3deuB-2vhlA:16.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vn7 | GLUCOAMYLASE (Trichodermareesei) |
PF00686(CBM_20)PF00723(Glyco_hydro_15) | 4 | THR A 10SER A 425LEU A 427THR A 430 | None | 0.96A | 3deuB-2vn7A:undetectable | 3deuB-2vn7A:11.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2vrc | TRIPHENYLMETHANEREDUCTASE (Citrobacter sp.MY-5) |
PF05368(NmrA) | 4 | THR A 174THR A 144LEU A 277THR A 280 | None | 0.80A | 3deuB-2vrcA:undetectable | 3deuB-2vrcA:20.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wfi | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEG (Homo sapiens) |
PF00160(Pro_isomerase) | 4 | THR A 131SER A 111LEU A 109THR A 127 | None | 0.84A | 3deuB-2wfiA:undetectable | 3deuB-2wfiA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wsu | PUTATIVE FIBERPROTEIN (PorcinemastadenovirusB) |
PF00337(Gal-bind_lectin) | 4 | THR A 560THR A 639ILE A 666LEU A 663 | None | 0.89A | 3deuB-2wsuA:undetectable | 3deuB-2wsuA:20.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zbk | TYPE 2 DNATOPOISOMERASE 6SUBUNIT B (Sulfolobusshibatae) |
PF02518(HATPase_c)PF09239(Topo-VIb_trans) | 4 | ILE B 56SER B 43LEU B 44THR B 47 | NoneRDC B 531 (-3.2A)NoneNone | 0.79A | 3deuB-2zbkB:undetectable | 3deuB-2zbkB:15.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zux | YESW PROTEIN (Bacillussubtilis) |
no annotation | 4 | THR A 269ILE A 203LEU A 205THR A 235 | None | 0.74A | 3deuB-2zuxA:undetectable | 3deuB-2zuxA:13.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zuy | YESX PROTEIN (Bacillussubtilis) |
PF01839(FG-GAP) | 4 | THR A 236ILE A 170LEU A 172THR A 202 | None | 0.76A | 3deuB-2zuyA:undetectable | 3deuB-2zuyA:12.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3a24 | ALPHA-GALACTOSIDASE (Bacteroidesthetaiotaomicron) |
PF10566(Glyco_hydro_97)PF14508(GH97_N)PF14509(GH97_C) | 4 | ILE A 272SER A 288LEU A 287THR A 285 | None | 0.93A | 3deuB-3a24A:undetectable | 3deuB-3a24A:10.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3am3 | ENOYL-ACP REDUCTASE (Plasmodiumfalciparum) |
PF13561(adh_short_C2) | 4 | THR A 410THR A 309LEU A 288THR A 266 | None | 0.94A | 3deuB-3am3A:undetectable | 3deuB-3am3A:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b0h | NITRITE REDUCTASE (Nicotianatabacum) |
PF01077(NIR_SIR)PF03460(NIR_SIR_ferr) | 4 | THR A 122ILE A 404LEU A 396THR A 117 | None | 0.90A | 3deuB-3b0hA:undetectable | 3deuB-3b0hA:18.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bt6 | INFLUENZA BHEMAGGLUTININ (HA) (Influenza Bvirus) |
PF00509(Hemagglutinin) | 4 | THR A 47THR A 49ILE A 315LEU A 293 | None | 0.96A | 3deuB-3bt6A:undetectable | 3deuB-3bt6A:16.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3co8 | ALANINE RACEMASE (Oenococcus oeni) |
PF00842(Ala_racemase_C)PF01168(Ala_racemase_N) | 4 | THR A 165ILE A 189LEU A 188THR A 131 | None | 0.93A | 3deuB-3co8A:undetectable | 3deuB-3co8A:19.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3d2l | SAM-DEPENDENTMETHYLTRANSFERASE (Exiguobacteriumsibiricum) |
PF13649(Methyltransf_25) | 4 | THR A 118ILE A 101SER A 105LEU A 106 | None | 0.77A | 3deuB-3d2lA:undetectable | 3deuB-3d2lA:21.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3dy5 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | THR A 765SER A 934LEU A 935THR A 938 | None | 0.91A | 3deuB-3dy5A:undetectable | 3deuB-3dy5A:8.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euj | CHROMOSOME PARTITIONPROTEIN MUKB, LINKER ([Haemophilus]ducreyi) |
PF04310(MukB)PF13558(SbcCD_C) | 4 | THR A1378ILE A 238SER A1390LEU A1393 | None | 0.82A | 3deuB-3eujA:1.7 | 3deuB-3eujA:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3f4b | ENOYL-ACYL CARRIERPROTEIN REDUCTASE (Plasmodiumberghei) |
PF13561(adh_short_C2) | 4 | THR A 374THR A 294LEU A 273THR A 251 | None | 0.97A | 3deuB-3f4bA:undetectable | 3deuB-3f4bA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fg4 | ALLENE OXIDESYNTHASE-LIPOXYGENASE PROTEIN (Plexaurahomomalla) |
PF00305(Lipoxygenase)PF01477(PLAT) | 4 | THR A 765SER A 934LEU A 935THR A 938 | None | 0.82A | 3deuB-3fg4A:undetectable | 3deuB-3fg4A:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3jb9 | PEPTIDYL-PROLYLCIS-TRANS ISOMERASEPPI1 (Schizosaccharomycespombe) |
PF01423(LSM) | 4 | THR d 109ILE d 118SER d 89THR d 105 | None | 0.74A | 3deuB-3jb9d:undetectable | 3deuB-3jb9d:21.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3k6k | ESTERASE/LIPASE (unculturedbacterium) |
PF07859(Abhydrolase_3) | 4 | THR A 164ILE A 245SER A 257LEU A 260 | None | 0.91A | 3deuB-3k6kA:undetectable | 3deuB-3k6kA:19.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3l6v | DNA GYRASE SUBUNIT A (Xanthomonascampestris) |
PF03989(DNA_gyraseA_C) | 4 | THR A 653THR A 649ILE A 673LEU A 675 | None | 0.91A | 3deuB-3l6vA:undetectable | 3deuB-3l6vA:18.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3mq0 | TRANSCRIPTIONALREPRESSOR OF THEBLCABC OPERON (Agrobacteriumtumefaciens) |
PF01614(IclR)PF09339(HTH_IclR) | 4 | THR A 105ILE A 225SER A 265LEU A 268 | None | 0.88A | 3deuB-3mq0A:5.3 | 3deuB-3mq0A:20.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o3x | GP41-5 (syntheticconstruct) |
no annotation | 4 | THR A 105THR A 24LEU A 183THR A 186 | NoneMPD A 199 ( 4.6A)NoneNone | 0.96A | 3deuB-3o3xA:undetectable | 3deuB-3o3xA:20.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3o7t | CYCLOPHILIN A (Moniliophthoraperniciosa) |
PF00160(Pro_isomerase) | 4 | THR A 117SER A 97LEU A 95THR A 113 | None | 0.89A | 3deuB-3o7tA:undetectable | 3deuB-3o7tA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ogr | BETA-GALACTOSIDASE (Trichodermareesei) |
PF01301(Glyco_hydro_35)PF10435(BetaGal_dom2)PF13363(BetaGal_dom3)PF13364(BetaGal_dom4_5) | 4 | THR A 475ILE A 456LEU A 454THR A 449 | None | 0.81A | 3deuB-3ogrA:undetectable | 3deuB-3ogrA:9.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3pie | 5'->3'EXORIBONUCLEASE(XRN1) (Kluyveromyceslactis) |
PF03159(XRN_N) | 4 | THR A 814THR A 811SER A 783LEU A 782 | None | 0.74A | 3deuB-3pieA:undetectable | 3deuB-3pieA:8.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3prl | NADP-DEPENDENTGLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE (Bacillushalodurans) |
PF00171(Aldedh) | 4 | THR A 179SER A 472LEU A 471THR A 474 | None | 0.95A | 3deuB-3prlA:undetectable | 3deuB-3prlA:15.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qpt | TRANSCRIPTIONALREGULATOR SLYA (Salmonellaenterica) |
PF01047(MarR) | 5 | THR A 32THR A 36SER A 62LEU A 63THR A 66 | None | 0.71A | 3deuB-3qptA:17.4 | 3deuB-3qptA:94.16 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3qpt | TRANSCRIPTIONALREGULATOR SLYA (Salmonellaenterica) |
PF01047(MarR) | 5 | THR A 36ILE A 58SER A 62LEU A 63THR A 66 | None | 0.73A | 3deuB-3qptA:17.4 | 3deuB-3qptA:94.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3s51 | FANCONI ANEMIA GROUPI PROTEIN HOMOLOG (Mus musculus) |
PF14674(FANCI_S1-cap)PF14675(FANCI_S1)PF14676(FANCI_S2)PF14677(FANCI_S3)PF14678(FANCI_S4)PF14679(FANCI_HD1)PF14680(FANCI_HD2) | 4 | THR A1006ILE A 982SER A1023LEU A1024 | None | 0.96A | 3deuB-3s51A:undetectable | 3deuB-3s51A:8.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7v | METHYLORNITHINESYNTHASE PYLB (Methanosarcinabarkeri) |
PF04055(Radical_SAM) | 4 | THR A 219SER A 257LEU A 256THR A 210 | None | 0.93A | 3deuB-3t7vA:undetectable | 3deuB-3t7vA:18.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3uw3 | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Burkholderiathailandensis) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | THR A 70ILE A 130LEU A 100THR A 77 | None | 0.94A | 3deuB-3uw3A:undetectable | 3deuB-3uw3A:16.27 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wec | CYTOCHROME P450 (Rhodococcuserythropolis) |
PF00067(p450) | 4 | ILE A 167SER A 162LEU A 165THR A 251 | None | 0.92A | 3deuB-3wecA:undetectable | 3deuB-3wecA:18.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wxm | PROTEIN PELOTAHOMOLOG (Aeropyrumpernix) |
PF03463(eRF1_1)PF03465(eRF1_3) | 4 | THR B 96ILE B 60LEU B 58THR B 40 | None | 0.56A | 3deuB-3wxmB:undetectable | 3deuB-3wxmB:23.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3x38 | MITOCHONDRIALMORPHOGENESISPROTEIN SLD7 (Saccharomycescerevisiae) |
no annotation | 4 | THR A 222SER A 242LEU A 243THR A 246 | None | 0.91A | 3deuB-3x38A:undetectable | 3deuB-3x38A:18.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a64 | CULLIN-4B (Homo sapiens) |
PF00888(Cullin) | 4 | THR A 375SER A 421LEU A 422THR A 425 | None | 0.76A | 3deuB-4a64A:undetectable | 3deuB-4a64A:18.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ac1 | ENDO-N-ACETYL-BETA-D-GLUCOSAMINIDASE (Trichodermareesei) |
PF00704(Glyco_hydro_18) | 4 | ILE X 234SER X 238LEU X 239THR X 242 | None | 0.61A | 3deuB-4ac1X:undetectable | 3deuB-4ac1X:18.90 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4aij | TRANSCRIPTIONALREGULATOR SLYA (Yersiniapseudotuberculosis) |
PF01047(MarR) | 4 | THR A 32THR A 36LEU A 63THR A 66 | None | 0.46A | 3deuB-4aijA:17.9 | 3deuB-4aijA:63.01 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4aij | TRANSCRIPTIONALREGULATOR SLYA (Yersiniapseudotuberculosis) |
PF01047(MarR) | 4 | THR A 36ILE A 58LEU A 63THR A 66 | None | 0.65A | 3deuB-4aijA:17.9 | 3deuB-4aijA:63.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4cag | POLYSACCHARIDE LYASEFAMILY 11 PROTEIN (Bacilluslicheniformis) |
PF01839(FG-GAP) | 4 | THR A 239ILE A 173LEU A 175THR A 205 | None | 0.75A | 3deuB-4cagA:undetectable | 3deuB-4cagA:14.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4eyv | PEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Serendipitaindica) |
PF00160(Pro_isomerase) | 4 | THR A 119SER A 99LEU A 97THR A 115 | None | 0.85A | 3deuB-4eyvA:undetectable | 3deuB-4eyvA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fha | DIHYDRODIPICOLINATESYNTHASE (Streptococcuspneumoniae) |
PF00701(DHDPS) | 4 | THR A 13ILE A 34LEU A 38THR A 42 | None | 0.84A | 3deuB-4fhaA:undetectable | 3deuB-4fhaA:18.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fmc | RORF2 (Escherichiacoli) |
PF06872(EspG) | 4 | THR A 393THR A 362LEU A 173THR A 176 | None | 0.91A | 3deuB-4fmcA:undetectable | 3deuB-4fmcA:18.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fqj | HEMAGGLUTININ (Influenza Bvirus) |
PF00509(Hemagglutinin) | 4 | THR A 47THR A 49ILE A 315LEU A 293 | None | 0.93A | 3deuB-4fqjA:undetectable | 3deuB-4fqjA:18.10 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4g1p | CYS-GLYMETALLODIPEPTIDASEDUG1 (Saccharomycescerevisiae) |
PF01546(Peptidase_M20)PF07687(M20_dimer) | 4 | THR A 165ILE A 61SER A 50LEU A 53 | None | 0.95A | 3deuB-4g1pA:undetectable | 3deuB-4g1pA:15.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h1x | PHOSPHATE-BINDINGPROTEIN PSTS 2 (Streptococcuspneumoniae) |
PF12849(PBP_like_2) | 4 | ILE A 97SER A 101LEU A 102THR A 103 | None | 0.83A | 3deuB-4h1xA:undetectable | 3deuB-4h1xA:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h8n | CONJUGATEDPOLYKETONE REDUCTASEC2 (Candidaparapsilosis) |
PF00248(Aldo_ket_red) | 4 | THR A 59ILE A 46LEU A 42THR A 65 | None | 0.90A | 3deuB-4h8nA:undetectable | 3deuB-4h8nA:19.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hkt | INOSITOL2-DEHYDROGENASE (Sinorhizobiummeliloti) |
PF01408(GFO_IDH_MocA)PF02894(GFO_IDH_MocA_C) | 4 | THR A 74ILE A 54LEU A 8THR A 70 | None | 0.81A | 3deuB-4hktA:undetectable | 3deuB-4hktA:17.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4hqs | THIOREDOXIN FAMILYPROTEIN (Streptococcuspneumoniae) |
PF00578(AhpC-TSA) | 4 | THR A 109SER A 90LEU A 91THR A 94 | None | 0.81A | 3deuB-4hqsA:undetectable | 3deuB-4hqsA:23.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jwy | GLUTAMATE RECEPTORIONOTROPIC, NMDA 2D (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 4 | THR A 134THR A 243ILE A 136THR A 116 | NoneNoneNone1N4 A 301 (-3.6A) | 0.97A | 3deuB-4jwyA:undetectable | 3deuB-4jwyA:19.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mla | CYTOKININ OXIDASE 2 (Zea mays) |
PF01565(FAD_binding_4)PF09265(Cytokin-bind) | 4 | THR A 163ILE A 224SER A 169LEU A 168 | FAD A 601 (-2.9A)FAD A 601 (-3.9A)FAD A 601 (-3.2A)None | 0.96A | 3deuB-4mlaA:undetectable | 3deuB-4mlaA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4r3u | 2-HYDROXYISOBUTYRYL-COA MUTASE LARGESUBUNIT (Aquincolatertiaricarbonis) |
PF01642(MM_CoA_mutase) | 4 | THR A 116ILE A 144LEU A 153THR A 99 | None | 0.95A | 3deuB-4r3uA:1.5 | 3deuB-4r3uA:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4w87 | XYLOGLUCAN-SPECIFICENDO-BETA-1,4-GLUCANASE (unculturedbacterium) |
PF00150(Cellulase) | 4 | THR A 133ILE A 151LEU A 113THR A 112 | None | 0.97A | 3deuB-4w87A:undetectable | 3deuB-4w87A:16.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wwu | MRNA TRANSPORTREGULATOR MTR2 (Saccharomycescerevisiae) |
PF10429(Mtr2) | 4 | THR C 19THR C 23ILE C 153LEU C 151 | None | 0.78A | 3deuB-4wwuC:undetectable | 3deuB-4wwuC:17.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4wy9 | PUTATIVE MCP-TYPESIGNAL TRANSDUCTIONPROTEIN (Campylobacterjejuni) |
PF02743(dCache_1) | 4 | THR A 99ILE A 213SER A 72LEU A 75 | None | 0.67A | 3deuB-4wy9A:undetectable | 3deuB-4wy9A:17.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4xgj | UNCHARACTERIZEDPROTEIN (Pectobacteriumatrosepticum) |
PF07005(DUF1537)PF17042(DUF1357_C) | 4 | THR A 312ILE A 378SER A 340LEU A 343 | None | 0.95A | 3deuB-4xgjA:undetectable | 3deuB-4xgjA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5bnt | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Pseudomonasaeruginosa) |
no annotation | 4 | THR C 71ILE C 131LEU C 101THR C 78 | None | 0.95A | 3deuB-5bntC:undetectable | 3deuB-5bntC:19.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ckm | MANNAN-BINDINGLECTIN SERINEPEPTIDASE 2 (Rattusnorvegicus) |
PF00431(CUB)PF07645(EGF_CA) | 4 | THR A 78THR A 76SER A 50LEU A 49 | None | 0.92A | 3deuB-5ckmA:undetectable | 3deuB-5ckmA:18.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5cxf | ENVELOPEGLYCOPROTEIN B (Humanbetaherpesvirus5) |
PF00606(Glycoprotein_B)PF17416(Glycoprot_B_PH1)PF17417(Glycoprot_B_PH2) | 4 | THR A 255THR A 253ILE A 332THR A 270 | None | 0.83A | 3deuB-5cxfA:undetectable | 3deuB-5cxfA:13.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5czl | GLUCANASE (Raoultellaornithinolytica) |
PF01270(Glyco_hydro_8) | 4 | THR A 94SER A 126LEU A 127THR A 131 | None | 0.83A | 3deuB-5czlA:undetectable | 3deuB-5czlA:19.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ern | FUSICOCCADIENESYNTHASE (Diaportheamygdali) |
PF00348(polyprenyl_synt) | 4 | ILE A 286SER A 291LEU A 292THR A 295 | None | 0.63A | 3deuB-5ernA:undetectable | 3deuB-5ernA:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5iob | BETA-GLUCOSIDASE-RELATED GLYCOSIDASES (Corynebacteriumglutamicum) |
PF00933(Glyco_hydro_3) | 4 | THR A 214SER A 268LEU A 267THR A 270 | None | 0.91A | 3deuB-5iobA:undetectable | 3deuB-5iobA:17.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nva | PUTATIVESODIUM:SOLUTESYMPORTER (Proteusmirabilis) |
no annotation | 4 | THR A 264ILE A 179SER A 53THR A 273 | None | 0.92A | 3deuB-5nvaA:undetectable | 3deuB-5nvaA:15.48 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5opt | ACTIVATED PROTEINKINASE C RECEPTOR,PUTATIVE (Trypanosomacruzi) |
no annotation | 4 | THR p 27SER p 76LEU p 75THR p 25 | None | 0.85A | 3deuB-5optp:undetectable | 3deuB-5optp:19.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vmn | BAK PROTEIN (Singaporegrouperiridovirus) |
no annotation | 4 | THR A 30ILE A 72SER A 73LEU A 75 | None | 0.93A | 3deuB-5vmnA:undetectable | 3deuB-5vmnA:20.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wuq | ECF RNA POLYMERASESIGMA FACTOR SIGW (Bacillussubtilis) |
PF04542(Sigma70_r2)PF08281(Sigma70_r4_2) | 4 | THR A 143ILE A 158LEU A 162THR A 78 | None | 0.95A | 3deuB-5wuqA:3.1 | 3deuB-5wuqA:22.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5x5t | ALPHA-KETOGLUTARICSEMIALDEHYDEDEHYDROGENASE (Azospirillumbrasilense) |
PF00171(Aldedh) | 4 | THR A 9THR A 7SER A 186LEU A 91 | None | 0.92A | 3deuB-5x5tA:undetectable | 3deuB-5x5tA:17.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yba | PEPTIDYL-PROLYLCIS-TRANS ISOMERASE (Trichomonasvaginalis) |
no annotation | 4 | THR A 127SER A 107LEU A 105THR A 123 | None | 0.84A | 3deuB-5ybaA:undetectable | 3deuB-5ybaA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5zvs | PUTATIVE COREPROTEIN NTPASE/VP5VP2 (Aquareovirus C) |
no annotation | 4 | THR 2 652ILE 2 515SER 4 218THR 2 631 | None | 0.78A | 3deuB-5zvs2:undetectable | 3deuB-5zvs2:18.63 |