SIMILAR PATTERNS OF AMINO ACIDS FOR 3DD1_A_CFFA903_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1aor ALDEHYDE FERREDOXIN
OXIDOREDUCTASE

(Pyrococcus
furiosus) 		PF01314
(AFOR_C)
PF02730
(AFOR_N) 		4 ASN A 260
PHE A 261
ALA A 352
GLY A 349
 None
 0.91A 3dd1A-1aorA:
undetectable		 3dd1A-1aorA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ayz UBIQUITIN-CONJUGATIN
G ENZYME RAD6

(Saccharomyces
cerevisiae) 		PF00179
(UQ_con) 		4 ASN A 114
HIS A  78
GLY A  42
TYR A  48
 None
 1.07A 3dd1A-1ayzA:
undetectable		 3dd1A-1ayzA:
12.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1e4o MALTODEXTRIN
PHOSPHORYLASE

(Escherichia
coli) 		PF00343
(Phosphorylase) 		4 HIS A 536
ALA A 575
GLY A 577
TYR A 578
 GLC  A 995 (-4.4A)
GLC  A 995 (-3.5A)
None
GLC  A 995 (-3.8A)
 0.76A 3dd1A-1e4oA:
49.7		 3dd1A-1e4oA:
42.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1eyy ALDEHYDE
DEHYDROGENASE

(Vibrio harveyi) 		PF00171
(Aldedh) 		4 ASN A 147
HIS A 177
ALA A 145
GLY A 229
 None
None
None
NAP  A 650 (-3.7A)
 1.14A 3dd1A-1eyyA:
undetectable		 3dd1A-1eyyA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ig8 HEXOKINASE PII

(Saccharomyces
cerevisiae) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 ASN A 267
ALA A 239
GLY A 238
TYR A 240
 None
 1.08A 3dd1A-1ig8A:
undetectable		 3dd1A-1ig8A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1omo ALANINE
DEHYDROGENASE

(Archaeoglobus
fulgidus) 		PF02423
(OCD_Mu_crystall) 		4 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.06A 3dd1A-1omoA:
2.1		 3dd1A-1omoA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pz1 GENERAL STRESS
PROTEIN 69

(Bacillus
subtilis) 		PF00248
(Aldo_ket_red) 		4 HIS A 125
ALA A  56
GLY A  58
TYR A  57
 NAP  A 500 ( 4.8A)
None
None
None
 1.15A 3dd1A-1pz1A:
2.0		 3dd1A-1pz1A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vjz ENDOGLUCANASE

(Thermotoga
maritima) 		PF00150
(Cellulase) 		4 PHE A  30
ALA A  34
GLY A  78
TYR A  77
 None
 1.11A 3dd1A-1vjzA:
undetectable		 3dd1A-1vjzA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1wif RIKEN CDNA
4930408O21

(Mus musculus) 		PF00595
(PDZ) 		4 ASN A  58
HIS A  55
ALA A  63
GLY A  60
 None
 1.12A 3dd1A-1wifA:
undetectable		 3dd1A-1wifA:
10.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ygp YEAST GLYCOGEN
PHOSPHORYLASE

(Saccharomyces
cerevisiae) 		PF00343
(Phosphorylase) 		4 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.73A 3dd1A-1ygpA:
45.6		 3dd1A-1ygpA:
48.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1zef ALKALINE PHOSPHATASE

(Homo sapiens) 		PF00245
(Alk_phosphatase) 		4 ASN A  84
PHE A 107
ALA A  94
GLY A  93
 None
PHE  A 802 (-4.4A)
None
SEP  A  92 ( 2.4A)
 1.01A 3dd1A-1zefA:
undetectable		 3dd1A-1zefA:
21.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2c4m GLYCOGEN
PHOSPHORYLASE

(Corynebacterium
callunae) 		PF00343
(Phosphorylase) 		4 HIS A 525
ALA A 564
GLY A 566
TYR A 567
 None
 0.80A 3dd1A-2c4mA:
49.9		 3dd1A-2c4mA:
42.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2d3a GLUTAMINE SYNTHETASE

(Zea mays) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 HIS A 280
ALA A 283
GLY A 285
TYR A 284
 None
 1.07A 3dd1A-2d3aA:
undetectable		 3dd1A-2d3aA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ehq 1-PYRROLINE-5-CARBOX
YLATE DEHYDROGENASE

(Thermus
thermophilus) 		PF00171
(Aldedh) 		4 HIS A 250
ALA A  76
GLY A  72
TYR A 246
 None
 1.12A 3dd1A-2ehqA:
1.6		 3dd1A-2ehqA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2fck RIBOSOMAL-PROTEIN-SE
RINE
ACETYLTRANSFERASE,
PUTATIVE

(Vibrio cholerae) 		PF13302
(Acetyltransf_3) 		4 ASN A  61
ALA A  67
GLY A  69
TYR A  68
 None
 1.14A 3dd1A-2fckA:
undetectable		 3dd1A-2fckA:
13.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2gj4 GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM

(Oryctolagus
cuniculus) 		PF00343
(Phosphorylase) 		6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.47A 3dd1A-2gj4A:
54.0		 3dd1A-2gj4A:
80.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gmh ELECTRON TRANSFER
FLAVOPROTEIN-UBIQUIN
ONE OXIDOREDUCTASE

(Sus scrofa) 		PF05187
(ETF_QO)
PF13450
(NAD_binding_8) 		4 HIS A 216
ALA A 332
GLY A 239
TYR A 238
 None
 0.98A 3dd1A-2gmhA:
2.2		 3dd1A-2gmhA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i00 ACETYLTRANSFERASE,
GNAT FAMILY

(Enterococcus
faecalis) 		PF13527
(Acetyltransf_9)
PF13530
(SCP2_2) 		4 ASN A 247
ALA A 250
GLY A 227
TYR A 245
 None
 1.08A 3dd1A-2i00A:
undetectable		 3dd1A-2i00A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2i7g MONOOXYGENASE

(Agrobacterium
fabrum) 		PF00296
(Bac_luciferase) 		4 ASN A 306
PHE A 304
HIS A 216
GLY A 302
 None
 1.00A 3dd1A-2i7gA:
2.5		 3dd1A-2i7gA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nwb CONSERVED DOMAIN
PROTEIN

(Shewanella
oneidensis) 		PF08933
(DUF1864) 		4 ASN A 235
ALA A 234
GLY A 233
TYR A 221
 HEM  A 401 (-2.6A)
None
None
None
 1.09A 3dd1A-2nwbA:
undetectable		 3dd1A-2nwbA:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2oaa R.MVAI

(Kocuria varians) 		PF15515
(MvaI_BcnI) 		4 HIS A 225
ALA A 212
GLY A 220
TYR A 213
 None
 1.14A 3dd1A-2oaaA:
undetectable		 3dd1A-2oaaA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ox4 PUTATIVE MANDELATE
RACEMASE

(Zymomonas
mobilis) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 ASN A 120
ALA A 332
GLY A 117
TYR A 113
 None
None
GOL  A3414 (-3.8A)
None
 0.96A 3dd1A-2ox4A:
undetectable		 3dd1A-2ox4A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pnc COPPER AMINE
OXIDASE, LIVER
ISOZYME

(Bos taurus) 		PF01179
(Cu_amine_oxid)
PF02727
(Cu_amine_oxidN2)
PF02728
(Cu_amine_oxidN3) 		4 PHE A 414
ALA A 342
GLY A 391
TYR A 392
 None
 1.02A 3dd1A-2pncA:
undetectable		 3dd1A-2pncA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rbb GLYOXALASE/BLEOMYCIN
RESISTANCE
PROTEIN/DIOXYGENASE

(Paraburkholderia
phytofirmans) 		PF00903
(Glyoxalase) 		4 ASN A  83
HIS A  85
ALA A  87
TYR A  88
 None
 1.13A 3dd1A-2rbbA:
undetectable		 3dd1A-2rbbA:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2rdy BH0842 PROTEIN

(Bacillus
halodurans) 		PF14498
(Glyco_hyd_65N_2) 		4 HIS A 421
ALA A 409
GLY A 414
TYR A 413
 None
 1.15A 3dd1A-2rdyA:
2.4		 3dd1A-2rdyA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2uv8 FATTY ACID SYNTHASE
SUBUNIT BETA (FAS1)

(Saccharomyces
cerevisiae) 		PF00698
(Acyl_transf_1)
PF01575
(MaoC_dehydratas)
PF08354
(DUF1729)
PF13452
(MaoC_dehydrat_N)
PF16073
(SAT) 		4 ASN G 153
HIS G 500
ALA G 148
GLY G 150
 None
 0.97A 3dd1A-2uv8G:
2.0		 3dd1A-2uv8G:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2v7y CHAPERONE PROTEIN
DNAK

(Geobacillus
kaustophilus) 		PF00012
(HSP70) 		4 ASN A 121
PHE A 120
ALA A 123
GLY A  72
 None
 1.09A 3dd1A-2v7yA:
undetectable		 3dd1A-2v7yA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wj3 1-H-3-HYDROXY-4-OXOQ
UINALDINE
2,4-DIOXYGENASE

(Paenarthrobacter
nitroguajacolicus) 		PF00561
(Abhydrolase_1) 		4 ASN A 199
ALA A 195
GLY A 197
TYR A 196
 None
 1.12A 3dd1A-2wj3A:
3.9		 3dd1A-2wj3A:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN

(Bordetella
bronchiseptica) 		PF04183
(IucA_IucC)
PF06276
(FhuF) 		4 PHE A 174
HIS A 130
GLY A 181
TYR A 179
 None
 1.13A 3dd1A-2x0qA:
2.1		 3dd1A-2x0qA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2y8d ERYTHROCYTE MEMBRANE
PROTEIN 1

(Plasmodium
falciparum) 		PF05424
(Duffy_binding) 		4 ASN A2352
ALA A2410
GLY A2412
TYR A2411
 None
 0.97A 3dd1A-2y8dA:
undetectable		 3dd1A-2y8dA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z3k LEUCYL/PHENYLALANYL-
TRNA-PROTEIN
TRANSFERASE

(Escherichia
coli) 		PF03588
(Leu_Phe_trans) 		4 PHE A  47
ALA A  41
GLY A  45
TYR A  42
 None
 1.05A 3dd1A-2z3kA:
undetectable		 3dd1A-2z3kA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zt9 CYTOCHROME B6
CYTOCHROME B6-F
COMPLEX SUBUNIT 5

(Nostoc sp. PCC
7120) 		PF00033
(Cytochrome_B)
PF02529
(PetG) 		4 ASN A  31
ALA G  24
GLY G  20
TYR G  23
 None
None
BCR  G 101 (-3.4A)
BCR  G 101 (-3.7A)
 1.02A 3dd1A-2zt9A:
undetectable		 3dd1A-2zt9A:
13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3b8p CHAIN LENGTH
DETERMINANT PROTEIN

(Salmonella
enterica) 		PF02706
(Wzz) 		4 ASN A  78
ALA A  85
GLY A  83
TYR A  81
 None
 1.13A 3dd1A-3b8pA:
undetectable		 3dd1A-3b8pA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3bws PROTEIN LP49

(Leptospira
interrogans) 		PF10282
(Lactonase) 		4 ASN A 435
HIS A 136
GLY A 379
TYR A 381
 None
 0.88A 3dd1A-3bwsA:
undetectable		 3dd1A-3bwsA:
19.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3cem GLYCOGEN
PHOSPHORYLASE, LIVER
FORM

(Homo sapiens) 		PF00343
(Phosphorylase) 		6 ASN A 282
PHE A 285
HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.86A 3dd1A-3cemA:
57.5		 3dd1A-3cemA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f44 PUTATIVE
MONOOXYGENASE

(Lactobacillus
acidophilus) 		PF03992
(ABM) 		4 ASN A 173
ALA A 176
GLY A 149
TYR A 171
 None
 1.06A 3dd1A-3f44A:
undetectable		 3dd1A-3f44A:
14.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fcr PUTATIVE
AMINOTRANSFERASE

(Ruegeria sp.
TM1040) 		PF00202
(Aminotran_3) 		4 ASN A 126
HIS A 322
GLY A 299
TYR A 114
 None
 1.14A 3dd1A-3fcrA:
undetectable		 3dd1A-3fcrA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3flo DNA POLYMERASE ALPHA
SUBUNIT B

(Saccharomyces
cerevisiae) 		PF04042
(DNA_pol_E_B)
PF08418
(Pol_alpha_B_N) 		4 ASN A 407
HIS A 440
ALA A 404
GLY A 660
 None
 1.14A 3dd1A-3floA:
undetectable		 3dd1A-3floA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3g7n LIPASE

(Penicillium
expansum) 		PF01764
(Lipase_3) 		4 ASN A 185
HIS A 131
ALA A 243
GLY A 246
 None
 1.04A 3dd1A-3g7nA:
undetectable		 3dd1A-3g7nA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gl1 HEAT SHOCK PROTEIN
SSB1

(Saccharomyces
cerevisiae) 		PF00012
(HSP70) 		4 ASN A 153
PHE A 152
ALA A 155
GLY A  77
 None
 1.07A 3dd1A-3gl1A:
undetectable		 3dd1A-3gl1A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gnq GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE, TYPE
I

(Burkholderia
pseudomallei) 		PF00044
(Gp_dh_N)
PF02800
(Gp_dh_C) 		4 ASN A 290
PHE A 287
ALA A 292
GLY A 276
 None
 0.82A 3dd1A-3gnqA:
2.0		 3dd1A-3gnqA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3i4j AMINOTRANSFERASE,
CLASS III

(Deinococcus
radiodurans) 		PF00202
(Aminotran_3) 		4 ASN A 171
ALA A 210
GLY A 212
TYR A 213
 None
 0.95A 3dd1A-3i4jA:
undetectable		 3dd1A-3i4jA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ldo 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo sapiens) 		PF00012
(HSP70) 		4 ASN A 177
PHE A 176
ALA A 179
GLY A 100
 None
 1.12A 3dd1A-3ldoA:
undetectable		 3dd1A-3ldoA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ll7 PUTATIVE
METHYLTRANSFERASE

(Porphyromonas
gingivalis) 		no annotation 4 PHE A 269
HIS A 295
ALA A 301
GLY A 302
 None
FMT  A 504 ( 4.1A)
None
None
 1.06A 3dd1A-3ll7A:
undetectable		 3dd1A-3ll7A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3o80 HEXOKINASE

(Kluyveromyces
lactis) 		PF00349
(Hexokinase_1)
PF03727
(Hexokinase_2) 		4 ASN A 266
ALA A 238
GLY A 237
TYR A 239
 None
 1.11A 3dd1A-3o80A:
undetectable		 3dd1A-3o80A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p24 BFT-3

(Bacteroides
fragilis) 		PF13583
(Reprolysin_4)
PF16376
(fragilysinNterm) 		4 ASN A 357
HIS A 348
ALA A 356
GLY A 355
 None
ZN  A 999 (-3.2A)
None
None
 0.97A 3dd1A-3p24A:
undetectable		 3dd1A-3p24A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3phg SHIKIMATE
DEHYDROGENASE

(Helicobacter
pylori) 		PF08501
(Shikimate_dh_N) 		4 HIS A  15
ALA A 209
GLY A 230
TYR A 210
 None
 1.05A 3dd1A-3phgA:
undetectable		 3dd1A-3phgA:
16.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qfw RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE/OXYGENAS
E LARGE SUBUNIT

(Rhodopseudomonas
palustris) 		PF00016
(RuBisCO_large) 		4 ASN A 192
HIS A 153
ALA A 156
GLY A 159
 None
 1.13A 3dd1A-3qfwA:
undetectable		 3dd1A-3qfwA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qj3 CATHEPSIN L-LIKE
PROTEIN

(Tenebrio
molitor) 		PF00112
(Peptidase_C1)
PF08246
(Inhibitor_I29) 		4 ASN A 287
PHE A 299
GLY A 248
TYR A 250
 None
 1.10A 3dd1A-3qj3A:
undetectable		 3dd1A-3qj3A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3qml 78 KDA
GLUCOSE-REGULATED
PROTEIN HOMOLOG

(Saccharomyces
cerevisiae) 		PF00012
(HSP70) 		4 ASN A 197
PHE A 196
ALA A 199
GLY A 121
 None
 1.10A 3dd1A-3qmlA:
undetectable		 3dd1A-3qmlA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3riq TAILSPIKE PROTEIN

(Salmonella
virus 9NA) 		PF09251
(PhageP22-tail) 		4 ASN A 355
PHE A 352
HIS A 440
GLY A 334
 None
 1.01A 3dd1A-3riqA:
undetectable		 3dd1A-3riqA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3u4j NAD-DEPENDENT
ALDEHYDE
DEHYDROGENASE

(Sinorhizobium
meliloti) 		PF00171
(Aldedh) 		4 ASN A 297
HIS A 349
ALA A 298
GLY A 342
 None
 1.10A 3dd1A-3u4jA:
4.9		 3dd1A-3u4jA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4c51 CATALASE-PEROXIDASE

(Mycobacterium
tuberculosis) 		PF00141
(peroxidase) 		4 PHE A 720
ALA A 716
GLY A 712
TYR A 711
 None
 1.02A 3dd1A-4c51A:
undetectable		 3dd1A-4c51A:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4czw PAB-DEPENDENT
POLY(A)-SPECIFIC
RIBONUCLEASE SUBUNIT
PAN2

(Neurospora
crassa) 		PF00929
(RNase_T)
PF13423
(UCH_1) 		4 HIS A 513
ALA A 806
GLY A 804
TYR A 514
 None
 0.94A 3dd1A-4czwA:
undetectable		 3dd1A-4czwA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4d72 GLYCOSIDE HYDROLASE

(Streptococcus
pneumoniae) 		PF08306
(Glyco_hydro_98M)
PF08307
(Glyco_hydro_98C) 		4 ASN A 591
ALA A 595
GLY A 593
TYR A 560
 None
None
None
NAG  A2009 (-4.6A)
 1.03A 3dd1A-4d72A:
undetectable		 3dd1A-4d72A:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hea NADH-QUINONE
OXIDOREDUCTASE
SUBUNIT 14

(Thermus
thermophilus) 		PF00361
(Proton_antipo_M) 		4 PHE N  48
ALA N  54
GLY N  51
TYR N  53
 None
 1.13A 3dd1A-4heaN:
2.2		 3dd1A-4heaN:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hpe PUTATIVE CELL WALL
HYDROLASE
TN916-LIKE,CTN1-ORF1
7

(Clostridioides
difficile) 		PF00877
(NLPC_P60)
PF13702
(Lysozyme_like) 		4 ASN A 139
HIS A 155
GLY A 141
TYR A 144
 GOL  A 406 ( 3.9A)
None
None
None
 1.08A 3dd1A-4hpeA:
undetectable		 3dd1A-4hpeA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4i3m AEROTAXIS TRANSDUCER
AER2

(Pseudomonas
aeruginosa) 		no annotation 4 PHE A 130
ALA A 124
GLY A 126
TYR A 125
 None
 0.93A 3dd1A-4i3mA:
undetectable		 3dd1A-4i3mA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jlw GLUTATHIONE-INDEPEND
ENT FORMALDEHYDE
DEHYDROGENASE

(Pseudomonas
aeruginosa) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 ASN A   4
HIS A 393
ALA A 137
GLY A   6
 None
 1.12A 3dd1A-4jlwA:
undetectable		 3dd1A-4jlwA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4l7t NANU SIALIC ACID
BINDING PROTEIN

(Bacteroides
fragilis) 		PF07980
(SusD_RagB)
PF14322
(SusD-like_3) 		4 ASN A  53
HIS A 141
ALA A  97
GLY A  98
 None
 1.09A 3dd1A-4l7tA:
undetectable		 3dd1A-4l7tA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4lyp EXO-BETA-1,4-MANNOSI
DASE

(Rhizomucor
miehei) 		no annotation 4 ASN A 166
PHE A 169
ALA A 165
TYR A 126
 None
 1.01A 3dd1A-4lypA:
undetectable		 3dd1A-4lypA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qfe ENOYL-COA HYDRATASE

(Mycolicibacterium
smegmatis) 		PF00378
(ECH_1) 		4 ASN A 176
ALA A 175
GLY A 173
TYR A 170
 None
 1.09A 3dd1A-4qfeA:
undetectable		 3dd1A-4qfeA:
14.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rtf CHAPERONE PROTEIN
DNAK

(Mycobacterium
tuberculosis) 		PF00012
(HSP70) 		4 ASN D 123
PHE D 122
ALA D 125
GLY D  74
 None
 1.11A 3dd1A-4rtfD:
undetectable		 3dd1A-4rtfD:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u0t ADC-7 BETA-LACTAMASE

(Acinetobacter
baumannii) 		PF00144
(Beta-lactamase) 		4 ASN A  79
ALA A 251
GLY A  74
TYR A  76
 None
 1.06A 3dd1A-4u0tA:
undetectable		 3dd1A-4u0tA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uis GAMMA-SECRETASE

(Homo sapiens) 		PF05450
(Nicastrin) 		4 PHE A 448
HIS A 449
ALA A 442
GLY A 366
 None
 1.13A 3dd1A-4uisA:
2.6		 3dd1A-4uisA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wjb PUTATIVE
AMIDOHYDROLASE/PEPTI
DASE

(Burkholderia
cenocepacia) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 PHE A 292
ALA A 265
GLY A 258
TYR A 261
 None
 1.01A 3dd1A-4wjbA:
undetectable		 3dd1A-4wjbA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wqt RNA CLEAVAGE
STIMULATING FACTOR
(GREA/GFH1 CHIMERIC
PROTEIN GRE-C1)

(Thermus
thermophilus) 		PF01272
(GreA_GreB)
PF03449
(GreA_GreB_N) 		4 PHE X  33
ALA X  36
GLY X  47
TYR X  48
 None
 1.01A 3dd1A-4wqtX:
2.2		 3dd1A-4wqtX:
11.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wy9 PUTATIVE MCP-TYPE
SIGNAL TRANSDUCTION
PROTEIN

(Campylobacter
jejuni) 		PF02743
(dCache_1) 		4 ASN A 265
HIS A 251
ALA A 289
GLY A 292
 ACT  A 401 ( 4.3A)
ACT  A 401 (-4.0A)
ACT  A 401 (-3.5A)
None
 1.05A 3dd1A-4wy9A:
undetectable		 3dd1A-4wy9A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4x9n L-ALPHA-GLYCEROPHOSP
HATE OXIDASE

(Mycoplasma
pneumoniae) 		PF01266
(DAO) 		4 ASN A  66
ALA A 353
GLY A  69
TYR A  65
 None
 1.13A 3dd1A-4x9nA:
undetectable		 3dd1A-4x9nA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgc ORIGIN RECOGNITION
COMPLEX SUBUNIT 2
ORIGIN RECOGNITION
COMPLEX SUBUNIT 3

(Drosophila
melanogaster) 		PF04084
(ORC2)
PF07034
(ORC3_N) 		4 ASN B 484
PHE B 351
GLY C 317
TYR C 320
 None
 1.09A 3dd1A-4xgcB:
undetectable		 3dd1A-4xgcB:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zgj NITRILE HYDRATASE
BETA SUBUNIT

(Comamonas
testosteroni) 		PF02211
(NHase_beta) 		4 ASN B  47
HIS B 135
ALA B 162
GLY B 165
 None
 1.12A 3dd1A-4zgjB:
undetectable		 3dd1A-4zgjB:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5af3 VAPBC49

(Mycobacterium
tuberculosis) 		PF04255
(DUF433) 		4 ASN A 182
ALA A 181
GLY A 179
TYR A 178
 None
 0.96A 3dd1A-5af3A:
undetectable		 3dd1A-5af3A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5e84 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Homo sapiens) 		PF00012
(HSP70) 		4 ASN A 177
PHE A 176
ALA A 179
GLY A 100
 None
 1.07A 3dd1A-5e84A:
undetectable		 3dd1A-5e84A:
22.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fn4 NICASTRIN

(Homo sapiens) 		PF05450
(Nicastrin) 		4 PHE A 448
HIS A 449
ALA A 442
GLY A 366
 None
 1.03A 3dd1A-5fn4A:
2.9		 3dd1A-5fn4A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gai TAIL FIBER PROTEIN

(Salmonella
virus P22) 		no annotation 4 ASN Y 340
PHE Y 337
HIS Y 427
GLY Y 348
 None
 1.06A 3dd1A-5gaiY:
undetectable		 3dd1A-5gaiY:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5h4r BETA-1,3-1,4-GLUCANA
SE

(Caldicellulosiruptor
sp. F32) 		PF00150
(Cellulase) 		4 ASN A 362
PHE A 372
ALA A 364
GLY A 369
 CTT  A 401 (-4.0A)
CTT  A 401 ( 4.5A)
None
None
 1.11A 3dd1A-5h4rA:
undetectable		 3dd1A-5h4rA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5iai SUGAR ABC
TRANSPORTER

(Agrobacterium
tumefaciens) 		PF01547
(SBP_bac_1) 		4 PHE A 356
HIS A 345
ALA A 353
GLY A 352
 None
 0.87A 3dd1A-5iaiA:
undetectable		 3dd1A-5iaiA:
19.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ikp GLYCOGEN
PHOSPHORYLASE, BRAIN
FORM

(Homo sapiens) 		PF00343
(Phosphorylase) 		4 HIS A 571
ALA A 610
GLY A 612
TYR A 613
 None
 0.77A 3dd1A-5ikpA:
51.3		 3dd1A-5ikpA:
81.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jjo UNCHARACTERIZED
PROTEIN

(Pseudomonas
aeruginosa) 		PF08238
(Sel1) 		4 ASN A 188
ALA A 185
GLY A 183
TYR A 184
 None
 1.12A 3dd1A-5jjoA:
undetectable		 3dd1A-5jjoA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k9h 0940_GH29

(unidentified) 		PF00754
(F5_F8_type_C)
PF01120
(Alpha_L_fucos) 		4 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.89A 3dd1A-5k9hA:
undetectable		 3dd1A-5k9hA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kqi CATALASE-PEROXIDASE

(Burkholderia
pseudomallei) 		PF00141
(peroxidase) 		4 PHE A 728
ALA A 724
GLY A 720
TYR A 719
 None
 0.99A 3dd1A-5kqiA:
undetectable		 3dd1A-5kqiA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kx4 10.7 KDA SALIVARY
PROTEIN

(Lutzomyia
longipalpis) 		no annotation 4 ASN A  13
PHE A  10
ALA A  14
TYR A  79
 None
 1.06A 3dd1A-5kx4A:
undetectable		 3dd1A-5kx4A:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5l2p ARYLESTERASE

(Sulfolobus
solfataricus) 		PF07859
(Abhydrolase_3) 		4 PHE A 185
HIS A 281
ALA A  85
GLY A 213
 None
 1.01A 3dd1A-5l2pA:
undetectable		 3dd1A-5l2pA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5mtv EH DOMAIN-CONTAINING
PROTEIN 4

(Mus musculus) 		PF00350
(Dynamin_N)
PF16880
(EHD_N) 		4 ASN A 137
ALA A 134
GLY A 132
TYR A 172
 None
 1.13A 3dd1A-5mtvA:
undetectable		 3dd1A-5mtvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5na4 NADH
DEHYDROGENASE-LIKE
PROTEIN
SAOUHSC_00878

(Staphylococcus
aureus) 		no annotation 4 PHE A 145
ALA A 149
GLY A 189
TYR A 188
 None
 1.06A 3dd1A-5na4A:
2.8		 3dd1A-5na4A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5obu CHAPERONE PROTEIN
DNAK

(Mycoplasma
genitalium) 		no annotation 4 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 None
 1.09A 3dd1A-5obuA:
undetectable		 3dd1A-5obuA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5obw CHAPERONE PROTEIN
DNAK

(Mycoplasma
genitalium) 		no annotation 4 ASN A 130
PHE A 129
ALA A 132
GLY A  76
 SO4  A 406 (-4.3A)
GOL  A 410 (-4.8A)
None
None
 1.11A 3dd1A-5obwA:
undetectable		 3dd1A-5obwA:
6.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5pep PEPSIN

(Sus scrofa) 		PF00026
(Asp) 		4 ASN A 180
ALA A 324
GLY A 177
TYR A 175
 None
 1.06A 3dd1A-5pepA:
undetectable		 3dd1A-5pepA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5uds LACTATE RACEMIZATION
OPERON PROTEIN LARE

(Lactobacillus
plantarum) 		PF02540
(NAD_synthase) 		4 ASN A 109
ALA A 142
GLY A 143
TYR A 105
 None
 1.11A 3dd1A-5udsA:
undetectable		 3dd1A-5udsA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8o HOMOSERINE
O-ACETYLTRANSFERASE

(Mycolicibacterium
hassiacum) 		PF00561
(Abhydrolase_1) 		4 PHE A 277
ALA A 279
GLY A 280
TYR A 282
 None
 1.13A 3dd1A-5w8oA:
undetectable		 3dd1A-5w8oA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8p HOMOSERINE
O-ACETYLTRANSFERASE

(Mycobacteroides
abscessus) 		PF00561
(Abhydrolase_1) 		4 PHE A 284
ALA A 286
GLY A 287
TYR A 289
 None
 1.15A 3dd1A-5w8pA:
2.7		 3dd1A-5w8pA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w8x LIPID-A-DISACCHARIDE
SYNTHASE

(Escherichia
coli) 		no annotation 4 ASN A 103
PHE A 102
ALA A  99
GLY A  14
 None
 0.78A 3dd1A-5w8xA:
6.1		 3dd1A-5w8xA:
5.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5wya ISOLEUCINE
2-EPIMERASE

(Lactobacillus
buchneri) 		PF00202
(Aminotran_3) 		4 ASN A 113
HIS A 306
ALA A 311
GLY A 312
 None
 1.14A 3dd1A-5wyaA:
undetectable		 3dd1A-5wyaA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5xbl CRISPR-ASSOCIATED
ENDONUCLEASE
CAS9/CSN1

(Streptococcus
pyogenes) 		PF13395
(HNH_4)
PF16592
(Cas9_REC)
PF16593
(Cas9-BH)
PF16595
(Cas9_PI) 		4 PHE A 351
ALA A 360
GLY A 358
TYR A 359
 G  B  43 ( 4.9A)
G  B  43 ( 3.4A)
None
G  B  43 ( 4.8A)
 0.81A 3dd1A-5xblA:
2.2		 3dd1A-5xblA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5y9d ACYL-COENZYME A
OXIDASE 1

(Yarrowia
lipolytica) 		no annotation 4 ASN A 428
PHE A 430
ALA A 636
GLY A 639
 None
 1.04A 3dd1A-5y9dA:
undetectable		 3dd1A-5y9dA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ys9 ACYL-COENZYME A
OXIDASE 3

(Yarrowia
lipolytica) 		no annotation 4 ASN A 439
PHE A 441
ALA A 646
GLY A 649
 None
 0.99A 3dd1A-5ys9A:
undetectable		 3dd1A-5ys9A:
6.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b7p SDED

(Legionella
pneumophila) 		no annotation 4 PHE A 176
HIS A  93
GLY A 182
TYR A 183
 None
 1.01A 3dd1A-6b7pA:
undetectable		 3dd1A-6b7pA:
6.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus) 		no annotation 4 ASN A 177
PHE A 176
ALA A 179
GLY A 100
 None
 1.06A 3dd1A-6eoeA:
undetectable		 3dd1A-6eoeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6f74 ALCOHOL OXIDASE

(Thermothelomyces
thermophila) 		no annotation 4 HIS A 301
ALA A 203
GLY A 201
TYR A 188
 None
 1.02A 3dd1A-6f74A:
undetectable		 3dd1A-6f74A:
7.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fyd PUTATIVE
FAD-DEPENDENT
OXYGENASE ENCM

(Streptomyces
maritimus) 		no annotation 4 ASN A 375
ALA A 431
GLY A 433
TYR A 432
 None
 1.07A 3dd1A-6fydA:
undetectable		 3dd1A-6fydA:
7.11