SIMILAR PATTERNS OF AMINO ACIDS FOR 3DCJ_B_THHB401
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bco | BACTERIOPHAGE MUTRANSPOSASE (Escherichiavirus Mu) |
PF02914(DDE_2)PF09299(Mu-transpos_C) | 4 | LEU A 260ASN A 267VAL A 295GLY A 386 | None | 0.74A | 3dcjB-1bcoA:undetectable | 3dcjB-1bcoA:21.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bt4 | PHOSPHOSERINEAMINOTRANSFERASE (Bacilluscirculans) |
PF00266(Aminotran_5) | 4 | SER A 176ASN A 151THR A 301GLY A 101 | PLP A 363 ( 3.9A)NoneNoneNone | 0.81A | 3dcjB-1bt4A:undetectable | 3dcjB-1bt4A:20.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1c3e | GLYCINAMIDERIBONUCLEOTIDETRANSFORMYLASE (Escherichiacoli) |
PF00551(Formyl_trans_N) | 4 | ILE A 91LEU A 92ASN A 106VAL A 139 | NHR A 220 (-4.3A)NHR A 220 (-3.9A)NHR A 220 (-3.0A)NHR A 220 (-4.5A) | 0.63A | 3dcjB-1c3eA:28.4 | 3dcjB-1c3eA:32.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1cvm | PHYTASE (Bacillusamyloliquefaciens) |
PF02333(Phytase) | 4 | ILE A 316LEU A 275THR A 310GLY A 261 | None | 0.83A | 3dcjB-1cvmA:undetectable | 3dcjB-1cvmA:20.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e5p | APHRODISIN (Mesocricetusauratus) |
PF00061(Lipocalin) | 4 | ILE A 125LEU A 126LEU A 118VAL A 111 | None | 0.86A | 3dcjB-1e5pA:undetectable | 3dcjB-1e5pA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1e6y | METHYL-COENZYME MREDUCTASE SUBUNITALPHA (Methanosarcinabarkeri) |
PF02249(MCR_alpha)PF02745(MCR_alpha_N) | 4 | SER A1517ILE A1511THR A1360GLY A1443 | None | 0.82A | 3dcjB-1e6yA:undetectable | 3dcjB-1e6yA:18.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fnf | FIBRONECTIN (Homo sapiens) |
PF00041(fn3) | 4 | ILE A1232LEU A1149THR A1157VAL A1162 | None | 0.83A | 3dcjB-1fnfA:undetectable | 3dcjB-1fnfA:23.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1h6f | T-BOX TRANSCRIPTIONFACTOR TBX3 (Homo sapiens) |
PF00907(T-box) | 4 | SER A 246ILE A 240LEU A 152VAL A 235 | None | 0.80A | 3dcjB-1h6fA:undetectable | 3dcjB-1h6fA:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jgc | BACTERIOFERRITIN (Rhodobactercapsulatus) |
PF00210(Ferritin) | 4 | SER A 116ILE A 8LEU A 11GLY A 67 | None | 0.74A | 3dcjB-1jgcA:undetectable | 3dcjB-1jgcA:22.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1krt | LYSYL-TRNASYNTHETASE (PRODUCTOF LYSS GENE) (Escherichiacoli) |
PF01336(tRNA_anti-codon) | 4 | SER A 46ILE A 138LEU A 128GLY A 126 | None | 0.73A | 3dcjB-1krtA:undetectable | 3dcjB-1krtA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1kzh | PHOSPHOFRUCTOKINASE (Borreliellaburgdorferi) |
PF00365(PFK) | 4 | SER A 92LEU A 79ASN A 89GLY A 138 | None | 0.81A | 3dcjB-1kzhA:2.7 | 3dcjB-1kzhA:15.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lam | LEUCINEAMINOPEPTIDASE (Bos taurus) |
PF00883(Peptidase_M17)PF02789(Peptidase_M17_N) | 4 | ILE A 284LEU A 230VAL A 200GLY A 298 | None | 0.83A | 3dcjB-1lamA:undetectable | 3dcjB-1lamA:20.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1mzh | DEOXYRIBOSE-PHOSPHATE ALDOLASE (Aquifexaeolicus) |
PF01791(DeoC) | 4 | SER A 129ILE A 122ASN A 110VAL A 137 | None | 0.70A | 3dcjB-1mzhA:undetectable | 3dcjB-1mzhA:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1p43 | ENOLASE 1 (Saccharomycescerevisiae) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 390THR A 397VAL A 369GLY A 393 | None | 0.60A | 3dcjB-1p43A:undetectable | 3dcjB-1p43A:21.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vig | VIGILIN (Homo sapiens) |
PF00013(KH_1) | 4 | SER A 76ILE A 32LEU A 24GLY A 29 | None | 0.87A | 3dcjB-1vigA:undetectable | 3dcjB-1vigA:14.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1zly | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Homo sapiens) |
PF00551(Formyl_trans_N) | 4 | ILE A 91LEU A 92ASN A 106VAL A 139 | DQB A1301 (-3.5A)DQB A1301 (-4.4A)DQB A1301 (-3.6A)DQB A1301 (-4.3A) | 0.57A | 3dcjB-1zlyA:29.4 | 3dcjB-1zlyA:37.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2akz | GAMMA ENOLASE (Homo sapiens) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 387THR A 394VAL A 366GLY A 390 | None | 0.73A | 3dcjB-2akzA:undetectable | 3dcjB-2akzA:22.64 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2b5m | DAMAGE-SPECIFIC DNABINDING PROTEIN 1 (Homo sapiens) |
PF03178(CPSF_A)PF10433(MMS1_N) | 5 | LEU A1000ASN A1005THR A 377VAL A1004GLY A1038 | None | 1.33A | 3dcjB-2b5mA:undetectable | 3dcjB-2b5mA:11.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bp1 | AFLATOXIN B1ALDEHYDE REDUCTASEMEMBER 2 (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | LEU A 92THR A 105VAL A 101GLY A 95 | None | 0.82A | 3dcjB-2bp1A:undetectable | 3dcjB-2bp1A:21.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2c91 | AFLATOXIN B1ALDEHYDE REDUCTASEMEMBER 2 (Mus musculus) |
PF00248(Aldo_ket_red) | 4 | LEU A 59THR A 72VAL A 68GLY A 62 | None | 0.79A | 3dcjB-2c91A:undetectable | 3dcjB-2c91A:22.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2clp | AFLATOXIN B1ALDEHYDE REDUCTASEMEMBER 3 (Homo sapiens) |
PF00248(Aldo_ket_red) | 4 | LEU A 92THR A 105VAL A 101GLY A 95 | None | 0.71A | 3dcjB-2clpA:undetectable | 3dcjB-2clpA:20.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2col | BIFUNCTIONALHEMOLYSIN-ADENYLATECYCLASE (Bordetellapertussis) |
PF03497(Anthrax_toxA) | 4 | LEU A 104THR A 114VAL A 78GLY A 178 | None | 0.76A | 3dcjB-2colA:undetectable | 3dcjB-2colA:22.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2e4u | METABOTROPICGLUTAMATE RECEPTOR 3 (Rattusnorvegicus) |
PF01094(ANF_receptor)PF07562(NCD3G) | 4 | ILE A 497LEU A 492THR A 296VAL A 468 | None | 0.72A | 3dcjB-2e4uA:3.1 | 3dcjB-2e4uA:17.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fkz | BACTERIOFERRITIN (Azotobactervinelandii) |
PF00210(Ferritin) | 4 | SER A 116ILE A 8LEU A 11GLY A 67 | None | 0.70A | 3dcjB-2fkzA:undetectable | 3dcjB-2fkzA:17.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fyi | HTH-TYPETRANSCRIPTIONALREGULATOR CBL (Escherichiacoli) |
PF03466(LysR_substrate) | 4 | ILE A 230LEU A 222THR A 202GLY A 241 | None | 0.87A | 3dcjB-2fyiA:undetectable | 3dcjB-2fyiA:22.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2fym | ENOLASE (Escherichiacoli) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 348LEU A 115THR A 323GLY A 346 | None | 0.81A | 3dcjB-2fymA:undetectable | 3dcjB-2fymA:21.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2gm8 | TENA HOMOLOG/THI-4THIAMINASE (Pyrobaculumaerophilum) |
PF03070(TENA_THI-4) | 4 | SER A 183LEU A 190LEU A 6VAL A 2 | None | 0.87A | 3dcjB-2gm8A:undetectable | 3dcjB-2gm8A:26.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2hcf | HYDROLASE, HALOACIDDEHALOGENASE-LIKEFAMILY (Chlorobaculumtepidum) |
PF13419(HAD_2) | 4 | SER A 58ILE A 52LEU A 29ASN A 59 | None | 0.86A | 3dcjB-2hcfA:3.2 | 3dcjB-2hcfA:22.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ift | PUTATIVE METHYLASEHI0767 (Haemophilusinfluenzae) |
PF03602(Cons_hypoth95) | 4 | ILE A 144LEU A 153THR A 163VAL A 129 | None | 0.78A | 3dcjB-2iftA:3.1 | 3dcjB-2iftA:21.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2iik | 3-KETOACYL-COATHIOLASE,PEROXISOMAL (Homo sapiens) |
PF00108(Thiolase_N)PF02803(Thiolase_C) | 4 | ILE A 389LEU A 392VAL A 40GLY A 43 | None | 0.76A | 3dcjB-2iikA:undetectable | 3dcjB-2iikA:23.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2l5e | BROMODOMAIN-CONTAINING PROTEIN 3 (Mus musculus) |
PF00439(Bromodomain) | 4 | LEU A 90THR A 107VAL A 47GLY A 84 | None | 0.86A | 3dcjB-2l5eA:undetectable | 3dcjB-2l5eA:19.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nq2 | HYPOTHETICAL ABCTRANSPORTER PERMEASEPROTEIN HI1471 (Haemophilusinfluenzae) |
PF01032(FecCD) | 4 | ILE A 267LEU A 270THR A 315GLY A 290 | None | 0.86A | 3dcjB-2nq2A:undetectable | 3dcjB-2nq2A:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2owo | DNA LIGASE (Escherichiacoli) |
PF01653(DNA_ligase_aden)PF03119(DNA_ligase_ZBD)PF03120(DNA_ligase_OB)PF12826(HHH_2)PF14520(HHH_5) | 4 | SER A 254ILE A 284LEU A 116GLY A 286 | None | 0.82A | 3dcjB-2owoA:undetectable | 3dcjB-2owoA:17.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2prx | THIOESTERASESUPERFAMILY PROTEIN (Shewanellaloihica) |
PF03061(4HBT) | 4 | SER A 72ILE A 65VAL A 129GLY A 143 | None | 0.68A | 3dcjB-2prxA:undetectable | 3dcjB-2prxA:23.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2pyw | UNCHARACTERIZEDPROTEIN (Arabidopsisthaliana) |
PF01636(APH) | 4 | ILE A 235LEU A 234ASN A 174GLY A 262 | None | 0.72A | 3dcjB-2pywA:undetectable | 3dcjB-2pywA:20.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qv6 | GTP CYCLOHYDROLASEIII (Methanocaldococcusjannaschii) |
PF05165(GCH_III) | 5 | SER A 90LEU A 126LEU A 66ASN A 124VAL A 122 | None | 1.45A | 3dcjB-2qv6A:undetectable | 3dcjB-2qv6A:21.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qz9 | ASPARTATE-SEMIALDEHYDE DEHYDROGENASE (Vibrio cholerae) |
PF01118(Semialdhyde_dh)PF02774(Semialdhyde_dhC) | 4 | ILE A 136LEU A 139ASN A 115VAL A 114 | None | 0.78A | 3dcjB-2qz9A:5.4 | 3dcjB-2qz9A:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r7h | PUTATIVE D-ALANINEN-ACETYLTRANSFERASEOF GNAT FAMILY (Desulfovibrioalaskensis) |
PF00583(Acetyltransf_1) | 4 | LEU A 96LEU A 130VAL A 118GLY A 85 | None | 0.73A | 3dcjB-2r7hA:undetectable | 3dcjB-2r7hA:23.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2uvf | EXOPOLYGALACTURONASE (Yersiniaenterocolitica) |
PF00295(Glyco_hydro_28)PF12708(Pectate_lyase_3) | 4 | SER A 388ILE A 383ASN A 362VAL A 365 | None | 0.70A | 3dcjB-2uvfA:undetectable | 3dcjB-2uvfA:17.69 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2w01 | ADENYLATE CYCLASE (Synechocystissp. PCC 6803) |
PF00211(Guanylate_cyc) | 5 | ILE A 541LEU A 630THR A 571VAL A 619GLY A 515 | None | 1.33A | 3dcjB-2w01A:undetectable | 3dcjB-2w01A:22.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2x4f | MYOSIN LIGHT CHAINKINASE FAMILY MEMBER4 (Homo sapiens) |
PF00069(Pkinase) | 4 | SER A 301ILE A 315LEU A 342VAL A 291 | None | 0.83A | 3dcjB-2x4fA:undetectable | 3dcjB-2x4fA:20.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2xsx | BETA-ENOLASE (Homo sapiens) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 388THR A 395VAL A 367GLY A 391 | None | 0.67A | 3dcjB-2xsxA:undetectable | 3dcjB-2xsxA:19.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yhg | CELLULOSE-BINDINGPROTEIN (Saccharophagusdegradans) |
PF07632(DUF1593) | 4 | ILE A 559ASN A 651THR A 569GLY A 626 | None | 0.72A | 3dcjB-2yhgA:3.7 | 3dcjB-2yhgA:17.81 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ywr | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Aquifexaeolicus) |
PF00551(Formyl_trans_N) | 4 | ILE A 92LEU A 93ASN A 107VAL A 140 | NoneNone CO A 704 ( 4.4A)None | 0.44A | 3dcjB-2ywrA:29.0 | 3dcjB-2ywrA:33.92 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2ywr | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Aquifexaeolicus) |
PF00551(Formyl_trans_N) | 4 | LEU A 93LEU A 98ASN A 107VAL A 140 | NoneNone CO A 704 ( 4.4A)None | 0.47A | 3dcjB-2ywrA:29.0 | 3dcjB-2ywrA:33.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2yx6 | HYPOTHETICAL PROTEINPH0822 (Pyrococcushorikoshii) |
PF02579(Nitro_FeMo-Co) | 4 | SER A 24ILE A 59LEU A 55VAL A 45 | None | 0.76A | 3dcjB-2yx6A:undetectable | 3dcjB-2yx6A:17.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3auf | GLYCINAMIDERIBONUCLEOTIDETRANSFORMYLASE 1 (Symbiobacteriumtoebii) |
PF00551(Formyl_trans_N) | 4 | LEU A 98ASN A 107VAL A 140GLY A 143 | None | 0.69A | 3dcjB-3aufA:30.2 | 3dcjB-3aufA:38.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3bqr | DEATH-ASSOCIATEDPROTEIN KINASE 3 (Homo sapiens) |
PF00069(Pkinase) | 4 | SER A 215ILE A 229LEU A 256VAL A 205 | None | 0.70A | 3dcjB-3bqrA:undetectable | 3dcjB-3bqrA:21.50 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3da8 | PROBABLE5'-PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASEPURN (Mycobacteriumtuberculosis) |
PF00551(Formyl_trans_N) | 5 | ILE A 101LEU A 102LEU A 107ASN A 116VAL A 149 | NoneNoneNone MG A 601 (-2.8A)None | 0.44A | 3dcjB-3da8A:34.2 | 3dcjB-3da8A:100.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3fi9 | MALATE DEHYDROGENASE (Porphyromonasgingivalis) |
PF00056(Ldh_1_N)PF02866(Ldh_1_C) | 4 | ILE A 102LEU A 106VAL A 12GLY A 83 | None | 0.87A | 3dcjB-3fi9A:5.4 | 3dcjB-3fi9A:19.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ftp | 3-OXOACYL-[ACYL-CARRIER PROTEIN]REDUCTASE (Burkholderiapseudomallei) |
PF13561(adh_short_C2) | 4 | SER A 123LEU A 170THR A 142GLY A 237 | None | 0.68A | 3dcjB-3ftpA:5.2 | 3dcjB-3ftpA:23.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gqp | HEMOGLOBIN SUBUNITBETA-A/B (Felis catus) |
PF00042(Globin) | 4 | LEU B 14ASN B 123VAL B 126GLY B 9 | None | 0.70A | 3dcjB-3gqpB:undetectable | 3dcjB-3gqpB:22.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3gvy | BACTERIOFERRITIN (Rhodobactersphaeroides) |
PF00210(Ferritin) | 4 | SER A 116ILE A 8LEU A 11GLY A 67 | None | 0.73A | 3dcjB-3gvyA:undetectable | 3dcjB-3gvyA:23.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3hjl | FLAGELLAR MOTORSWITCH PROTEIN FLIG (Aquifexaeolicus) |
PF01706(FliG_C)PF14841(FliG_M)PF14842(FliG_N) | 4 | SER A 279ILE A 242LEU A 262ASN A 280 | None | 0.76A | 3dcjB-3hjlA:undetectable | 3dcjB-3hjlA:20.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3if8 | PROTEIN ZWILCHHOMOLOG (Homo sapiens) |
PF09817(Zwilch) | 4 | ILE A 110LEU A 109THR A 148VAL A 64 | None | 0.79A | 3dcjB-3if8A:undetectable | 3dcjB-3if8A:22.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ist | GLUTAMATE RACEMASE (Listeriamonocytogenes) |
PF01177(Asp_Glu_race) | 4 | ILE A 180LEU A 181THR A 106GLY A 98 | None | 0.81A | 3dcjB-3istA:3.8 | 3dcjB-3istA:23.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3kbb | PHOSPHORYLATEDCARBOHYDRATESPHOSPHATASE TM_1254 (Thermotogamaritima) |
PF13419(HAD_2) | 5 | LEU A 123LEU A 93ASN A 86THR A 15VAL A 89 | LEU A 123 ( 0.6A)LEU A 93 ( 0.6A)ASN A 86 ( 0.6A)THR A 15 ( 0.8A)VAL A 89 ( 0.6A) | 1.35A | 3dcjB-3kbbA:3.7 | 3dcjB-3kbbA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3n58 | ADENOSYLHOMOCYSTEINASE (Brucellaabortus) |
PF00670(AdoHcyase_NAD)PF05221(AdoHcyase) | 4 | ILE A 186LEU A 141ASN A 415THR A 410 | None | 0.75A | 3dcjB-3n58A:4.8 | 3dcjB-3n58A:20.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3obi | FORMYLTETRAHYDROFOLATE DEFORMYLASE (Rhodopseudomonaspalustris) |
PF00551(Formyl_trans_N) | 4 | ILE A 177LEU A 178ASN A 192VAL A 225 | None | 0.75A | 3dcjB-3obiA:19.0 | 3dcjB-3obiA:28.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ow8 | WD REPEAT-CONTAININGPROTEIN 61 (Homo sapiens) |
PF00400(WD40) | 4 | SER A 165LEU A 163ASN A 173GLY A 180 | None | 0.85A | 3dcjB-3ow8A:undetectable | 3dcjB-3ow8A:23.99 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3p9x | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Bacillushalodurans) |
PF00551(Formyl_trans_N) | 4 | LEU A 98ASN A 107VAL A 140GLY A 143 | None | 0.64A | 3dcjB-3p9xA:26.5 | 3dcjB-3p9xA:33.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q33 | HISTONEACETYLTRANSFERASERTT109 (Saccharomycescerevisiae) |
PF08214(HAT_KAT11) | 4 | ILE A 111LEU A 65THR A 187VAL A 85 | NoneNoneNoneACO A 501 (-4.9A) | 0.79A | 3dcjB-3q33A:undetectable | 3dcjB-3q33A:18.46 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3q94 | FRUCTOSE-BISPHOSPHATE ALDOLASE, CLASS II (Bacillusanthracis) |
PF01116(F_bP_aldolase) | 4 | LEU A 173LEU A 206VAL A 198GLY A 203 | None | 0.76A | 3dcjB-3q94A:2.1 | 3dcjB-3q94A:26.28 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rjo | ENDOPLASMICRETICULUMAMINOPEPTIDASE 1 (Homo sapiens) |
PF11838(ERAP1_C) | 4 | LEU A 710LEU A 707THR A 629VAL A 673 | None | 0.85A | 3dcjB-3rjoA:undetectable | 3dcjB-3rjoA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3tr3 | BOLA (Coxiellaburnetii) |
PF01722(BolA) | 4 | SER A 18ILE A 7LEU A 68VAL A 51 | None | 0.87A | 3dcjB-3tr3A:undetectable | 3dcjB-3tr3A:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ue9 | ADENYLOSUCCINATESYNTHETASE (Burkholderiathailandensis) |
PF00709(Adenylsucc_synt) | 4 | SER A 336ILE A 275ASN A 340VAL A 342 | None | 0.72A | 3dcjB-3ue9A:undetectable | 3dcjB-3ue9A:22.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vss | BETA-FRUCTOFURANOSIDASE (Microbacteriumsaccharophilum) |
PF02435(Glyco_hydro_68) | 4 | LEU A 514THR A 485VAL A 490GLY A 516 | FRU A 604 (-3.7A)NoneNoneFRU A 604 ( 4.7A) | 0.81A | 3dcjB-3vssA:undetectable | 3dcjB-3vssA:18.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3wiq | KOJIBIOSEPHOSPHORYLASE (Caldicellulosiruptorsaccharolyticus) |
PF03632(Glyco_hydro_65m)PF03633(Glyco_hydro_65C)PF03636(Glyco_hydro_65N) | 4 | ILE A 34LEU A 27THR A 246GLY A 33 | None | 0.83A | 3dcjB-3wiqA:undetectable | 3dcjB-3wiqA:13.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a2l | TWO-COMPONENT SYSTEMSENSOR HISTIDINEKINASE/RESPONSE (Bacteroidesthetaiotaomicron) |
PF07494(Reg_prop)PF07495(Y_Y_Y) | 4 | LEU A 429LEU A 449VAL A 454GLY A 427 | None | 0.73A | 3dcjB-4a2lA:undetectable | 3dcjB-4a2lA:12.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4alz | YOP PROTEINSTRANSLOCATIONPROTEIN D (Yersiniaenterocolitica) |
PF16693(Yop-YscD_ppl) | 4 | LEU A 265LEU A 272ASN A 277VAL A 275 | None | 0.72A | 3dcjB-4alzA:undetectable | 3dcjB-4alzA:22.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ayg | GLUCANSUCRASE (Lactobacillusreuteri) |
PF01473(CW_binding_1)PF02324(Glyco_hydro_70) | 4 | ILE A1061LEU A1081ASN A1403VAL A1200 | NoneNoneGOL A2788 ( 4.7A)None | 0.85A | 3dcjB-4aygA:undetectable | 3dcjB-4aygA:14.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4f92 | U5 SMALL NUCLEARRIBONUCLEOPROTEIN200 KDA HELICASE (Homo sapiens) |
PF00270(DEAD)PF00271(Helicase_C)PF02889(Sec63) | 4 | SER B 420LEU B 887LEU B 655THR B 831 | None | 0.85A | 3dcjB-4f92B:undetectable | 3dcjB-4f92B:9.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fc7 | PEROXISOMAL2,4-DIENOYL-COAREDUCTASE (Homo sapiens) |
PF13561(adh_short_C2) | 4 | SER A 145LEU A 192THR A 164GLY A 262 | None | 0.86A | 3dcjB-4fc7A:5.2 | 3dcjB-4fc7A:26.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fdy | SIMILAR TOLIPOPROTEIN, NLP/P60FAMILY (Staphylococcusaureus) |
PF00877(NLPC_P60)PF13702(Lysozyme_like) | 4 | ILE A 221LEU A 285VAL A 337GLY A 283 | None | 0.81A | 3dcjB-4fdyA:undetectable | 3dcjB-4fdyA:19.57 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ga6 | PUTATIVE THYMIDINEPHOSPHORYLASE (Thermococcuskodakarensis) |
PF00591(Glycos_transf_3)PF02885(Glycos_trans_3N)PF07831(PYNP_C) | 4 | LEU A 361ASN A 175VAL A 178GLY A 356 | NoneSO4 A 602 (-3.8A)NoneNone | 0.72A | 3dcjB-4ga6A:4.3 | 3dcjB-4ga6A:17.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h0n | DNMT2 (Spodopterafrugiperda) |
PF00145(DNA_methylase) | 4 | SER A 229ILE A 197LEU A 194ASN A 156 | None | 0.87A | 3dcjB-4h0nA:5.3 | 3dcjB-4h0nA:20.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m03 | SERINE-RICH ADHESINFOR PLATELETS (Staphylococcusaureus) |
PF05345(He_PIG) | 4 | ILE A 137LEU A 156ASN A 151VAL A 153 | None | 0.78A | 3dcjB-4m03A:undetectable | 3dcjB-4m03A:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4m03 | SERINE-RICH ADHESINFOR PLATELETS (Staphylococcusaureus) |
PF05345(He_PIG) | 4 | LEU A 245ASN A 240THR A 210VAL A 242 | None | 0.84A | 3dcjB-4m03A:undetectable | 3dcjB-4m03A:19.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4mks | ENOLASE 2 (Lactobacillusgasseri) |
PF00113(Enolase_C)PF03952(Enolase_N) | 4 | LEU A 346LEU A 116THR A 321GLY A 344 | None | 0.79A | 3dcjB-4mksA:undetectable | 3dcjB-4mksA:21.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ng4 | PHOSPHOGLYCERATEKINASE (Coxiellaburnetii) |
PF00162(PGK) | 4 | LEU A 207LEU A 214ASN A 315VAL A 192 | NoneNoneADP A 402 (-3.1A)None | 0.87A | 3dcjB-4ng4A:3.7 | 3dcjB-4ng4A:22.56 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4s1n | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Streptococcuspneumoniae) |
PF00551(Formyl_trans_N) | 4 | ILE A 85LEU A 91ASN A 100VAL A 133 | NoneNone CL A 201 ( 4.1A)None | 0.58A | 3dcjB-4s1nA:26.5 | 3dcjB-4s1nA:35.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4s1n | PHOSPHORIBOSYLGLYCINAMIDEFORMYLTRANSFERASE (Streptococcuspneumoniae) |
PF00551(Formyl_trans_N) | 4 | LEU A 91ASN A 100VAL A 133GLY A 136 | None CL A 201 ( 4.1A)NoneNone | 0.65A | 3dcjB-4s1nA:26.5 | 3dcjB-4s1nA:35.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4u3g | BACTERIOFERRITIN (Escherichiacoli) |
PF00210(Ferritin) | 4 | SER A 116ILE A 8LEU A 11GLY A 67 | None | 0.71A | 3dcjB-4u3gA:undetectable | 3dcjB-4u3gA:17.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4yw5 | NEURAMINIDASE C (Streptococcuspneumoniae) |
PF02012(BNR)PF02973(Sialidase)PF13088(BNR_2) | 4 | LEU A 232LEU A 94ASN A 100GLY A 234 | None | 0.85A | 3dcjB-4yw5A:undetectable | 3dcjB-4yw5A:15.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5agt | LEUCINE--TRNA LIGASE (Mycobacteriumtuberculosis) |
PF13603(tRNA-synt_1_2) | 4 | LEU A 348ASN A 416THR A 341VAL A 423 | NoneNoneA2H A1514 (-3.6A)GOL A1515 (-4.3A) | 0.65A | 3dcjB-5agtA:undetectable | 3dcjB-5agtA:23.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5es6 | LINEAR GRAMICIDINSYNTHASE SUBUNIT A (Brevibacillusparabrevis) |
PF00501(AMP-binding)PF00551(Formyl_trans_N) | 4 | SER A 50ILE A 56LEU A 57ASN A 71 | FMT A 703 ( 3.6A)NoneFMT A 703 ( 4.5A)FMT A 702 (-3.0A) | 0.77A | 3dcjB-5es6A:12.7 | 3dcjB-5es6A:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ey2 | GTP-SENSINGTRANSCRIPTIONALPLEIOTROPICREPRESSOR CODY (Bacillus cereus) |
PF06018(CodY)PF08222(HTH_CodY) | 4 | SER A 28LEU A 126VAL A 150GLY A 124 | None | 0.68A | 3dcjB-5ey2A:undetectable | 3dcjB-5ey2A:24.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5fqd | DNA DAMAGE-BINDINGPROTEIN 1 (Homo sapiens) |
PF03178(CPSF_A)PF10433(MMS1_N) | 5 | LEU A1000ASN A1005THR A 377VAL A1004GLY A1038 | None | 1.38A | 3dcjB-5fqdA:undetectable | 3dcjB-5fqdA:14.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5gz4 | SNAKE VENOMPHOSPHODIESTERASE(PDE) (Naja atra) |
PF01033(Somatomedin_B)PF01223(Endonuclease_NS)PF01663(Phosphodiest) | 4 | SER A 297LEU A 286LEU A 341GLY A 335 | None | 0.84A | 3dcjB-5gz4A:undetectable | 3dcjB-5gz4A:13.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5hz5 | FATTY ACID-BINDINGPROTEIN, EPIDERMAL (Homo sapiens) |
PF00061(Lipocalin) | 4 | LEU A 52LEU A 69VAL A 4GLY A 49 | None | 0.86A | 3dcjB-5hz5A:undetectable | 3dcjB-5hz5A:22.94 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5j7z | PUTATIVE SECRETEDENDOGLYCOSYLCERAMIDASE (Rhodococcushoagii) |
PF00150(Cellulase) | 4 | ILE A 77LEU A 80ASN A 58VAL A 88 | None | 0.81A | 3dcjB-5j7zA:undetectable | 3dcjB-5j7zA:21.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5m8h | ATPPHOSPHORIBOSYLTRANSFERASE REGULATORYSUBUNIT (Psychrobacterarcticus) |
PF13393(tRNA-synt_His) | 4 | ILE A 136LEU A 152THR A 305VAL A 283 | MPD A 406 (-4.6A)NoneMPD A 406 (-3.8A)None | 0.80A | 3dcjB-5m8hA:undetectable | 3dcjB-5m8hA:22.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nbo | GLYCOSYL HYDROLASEFAMILY 16 (Bacteroidesovatus) |
no annotation | 4 | LEU A 255LEU A 252VAL A 239GLY A 122 | None | 0.81A | 3dcjB-5nboA:undetectable | 3dcjB-5nboA:21.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uvm | HISTIDINE TRIAD(HIT) PROTEIN (Ruminiclostridiumthermocellum) |
PF11969(DcpS_C) | 4 | ILE A 77LEU A 75VAL A 39GLY A 105 | None | 0.82A | 3dcjB-5uvmA:undetectable | 3dcjB-5uvmA:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5uxn | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATEALDOLASE (Pseudomonasaeruginosa) |
no annotation | 5 | ILE A 391LEU A 64THR A 442VAL A 103GLY A 390 | None | 1.20A | 3dcjB-5uxnA:undetectable | 3dcjB-5uxnA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6f | FLAGELLAR BRAKEPROTEIN YCGR (Escherichiacoli) |
no annotation | 4 | LEU A 32ASN A 62VAL A 65GLY A 37 | None | 0.75A | 3dcjB-5y6fA:undetectable | 3dcjB-5y6fA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5y6h | FLAGELLAR BRAKEPROTEIN YCGR (Escherichiacoli) |
no annotation | 4 | LEU A 32ASN A 62VAL A 65GLY A 37 | None | 0.72A | 3dcjB-5y6hA:undetectable | 3dcjB-5y6hA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5yo8 | TETRAPRENYL-BETA-CURCUMENE SYNTHASE (Bacillusalcalophilus) |
no annotation | 5 | ILE A 61LEU A 19THR A 218VAL A 22GLY A 58 | None | 1.50A | 3dcjB-5yo8A:undetectable | 3dcjB-5yo8A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6f72 | MTVAO615 (Thermothelomycesthermophila) |
no annotation | 4 | LEU A 278THR A 155VAL A 289GLY A 283 | NoneFAD A 601 (-2.8A)FAD A 601 (-3.8A)FAD A 601 ( 3.8A) | 0.86A | 3dcjB-6f72A:undetectable | 3dcjB-6f72A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6ffl | MALTOSE/MALTODEXTRINTRANSPORT PERMEASEHOMOLOGUE (Bdellovibriobacteriovorus) |
no annotation | 4 | LEU A 310LEU A 328VAL A 322GLY A 308 | None | 0.84A | 3dcjB-6fflA:undetectable | 3dcjB-6fflA:undetectable |