SIMILAR PATTERNS OF AMINO ACIDS FOR 3D1Y_A_ROCA201_2
List of similar pattern of amino acids derived from ASSAM searchHit | Macromolecule/ Organism |
Pfam | Res. | Interface | HETATM | RMSD | Dali Z-score | Seq. Identity (%) | View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1bou | 4,5-DIOXYGENASE BETACHAIN (Sphingomonaspaucimobilis) |
PF02900(LigB) | 5 | LEU B 133ILE B 277GLY B 7PRO B 51ILE B 136 | None | 1.13A | 3d1yB-1bouB:undetectable | 3d1yB-1bouB:14.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1fxl | PARANEOPLASTICENCEPHALOMYELITISANTIGEN HUD (Homo sapiens) |
PF00076(RRM_1) | 5 | LEU A 186GLY A 167ILE A 156VAL A 200ILE A 198 | None | 1.08A | 3d1yB-1fxlA:undetectable | 3d1yB-1fxlA:22.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1g5u | PROFILIN (Heveabrasiliensis) |
PF00235(Profilin) | 5 | ILE A1102GLY A1104ILE A1105VAL A1032ILE A1026 | None | 1.16A | 3d1yB-1g5uA:undetectable | 3d1yB-1g5uA:24.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 9 | ARG A 8LEU A 23ASP A 25ILE A 47GLY A 49ILE A 50PRO A 81VAL A 82ILE A 84 | A79 A 800 (-3.4A)A79 A 800 ( 3.8A)A79 A 800 (-2.7A)A79 A 800 ( 3.2A)A79 A 800 ( 3.7A)A79 A 800 (-3.8A)A79 A 800 ( 3.9A)A79 A 800 (-4.5A)A79 A 800 (-3.6A) | 0.60A | 3d1yB-1hvcA:13.9 | 3d1yB-1hvcA:46.31 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1hvc | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 9 | ARG A 8LEU A 23ASP A 25ILE A 47GLY A 49ILE A 50PRO A 81VAL A 82ILE A 84 | A79 A 800 (-3.6A)A79 A 800 ( 4.0A)A79 A 800 (-2.8A)A79 A 800 ( 3.4A)A79 A 800 (-3.4A)A79 A 800 ( 4.0A)A79 A 800 ( 3.4A)A79 A 800 (-4.5A)A79 A 800 (-3.8A) | 0.68A | 3d1yB-1hvcA:13.9 | 3d1yB-1hvcA:46.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ji6 | PESTICIDIAL CRYSTALPROTEIN CRY3BB (Bacillusthuringiensis) |
PF00555(Endotoxin_M)PF03944(Endotoxin_C)PF03945(Endotoxin_N) | 5 | LEU A 541ILE A 592ILE A 628VAL A 517ILE A 642 | None | 1.16A | 3d1yB-1ji6A:undetectable | 3d1yB-1ji6A:10.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqe | HISTAMINEN-METHYLTRANSFERASE (Homo sapiens) |
PF13489(Methyltransf_23) | 5 | LEU A 71ASP A 67ILE A 171ILE A 59ILE A 70 | None | 1.06A | 3d1yB-1jqeA:undetectable | 3d1yB-1jqeA:13.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1jqe | HISTAMINEN-METHYLTRANSFERASE (Homo sapiens) |
PF13489(Methyltransf_23) | 5 | LEU A 71ASP A 67ILE A 171ILE A 139ILE A 70 | None | 1.14A | 3d1yB-1jqeA:undetectable | 3d1yB-1jqeA:13.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1l6r | HYPOTHETICAL PROTEINTA0175 (Thermoplasmaacidophilum) |
PF08282(Hydrolase_3) | 5 | LEU A 40ILE A 217GLY A 215VAL A 9ILE A 7 | None | 0.98A | 3d1yB-1l6rA:undetectable | 3d1yB-1l6rA:19.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lk5 | D-RIBOSE-5-PHOSPHATEISOMERASE (Pyrococcushorikoshii) |
PF06026(Rib_5-P_isom_A) | 5 | LEU A 161ILE A 200GLY A 202ILE A 141ILE A 180 | None | 1.05A | 3d1yB-1lk5A:undetectable | 3d1yB-1lk5A:20.09 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1lua | METHYLENETETRAHYDROMETHANOPTERIN DEHYDROGENASE (Methylobacteriumextorquens) |
PF09176(Mpt_N) | 5 | LEU A 126ILE A 252GLY A 248ILE A 232VAL A 193 | None | 1.15A | 3d1yB-1luaA:undetectable | 3d1yB-1luaA:15.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1nba | N-CARBAMOYLSARCOSINEAMIDOHYDROLASE (Arthrobactersp.) |
PF00857(Isochorismatase) | 5 | ARG A 196LEU A 211ILE A 186ILE A 168ILE A 214 | None | 1.11A | 3d1yB-1nbaA:undetectable | 3d1yB-1nbaA:16.15 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1o94 | TRIMETHYLAMINEDEHYDROGENASE (Methylophilusmethylotrophus) |
PF00724(Oxidored_FMN)PF07992(Pyr_redox_2) | 5 | LEU A 650GLY A 668ILE A 666VAL A 395ILE A 485 | ADP A1731 ( 4.6A)NoneNoneADP A1731 (-4.7A)None | 0.94A | 3d1yB-1o94A:undetectable | 3d1yB-1o94A:10.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1oed | ACETYLCHOLINERECEPTOR PROTEIN,BETA CHAIN (Torpedomarmorata) |
PF02932(Neur_chan_memb) | 5 | LEU B 218ILE B 287ILE B 454VAL B 222ILE B 221 | None | 1.08A | 3d1yB-1oedB:undetectable | 3d1yB-1oedB:16.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1ohf | NUDAURELIA CAPENSISOMEGA VIRUS CAPSIDPROTEIN (Nudaureliacapensis omegavirus) |
PF03566(Peptidase_A21) | 5 | ARG A 194ILE A 155ILE A 475VAL A 217ILE A 215 | None | 1.15A | 3d1yB-1ohfA:undetectable | 3d1yB-1ohfA:11.54 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1poi | GLUTACONATE COENZYMEA-TRANSFERASE (Acidaminococcusfermentans) |
PF01144(CoA_trans) | 5 | ILE B 21GLY B 37ILE B 36VAL B 53ILE B 51 | None | 0.91A | 3d1yB-1poiB:undetectable | 3d1yB-1poiB:16.80 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1q90 | APOCYTOCHROME F (Chlamydomonasreinhardtii) |
PF01333(Apocytochr_F_C)PF16639(Apocytochr_F_N) | 5 | LEU A 83ILE A 244ILE A 76VAL A 128ILE A 130 | None | 1.13A | 3d1yB-1q90A:undetectable | 3d1yB-1q90A:18.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sd5 | PUTATIVEANTITERMINATOR (Mycobacteriumtuberculosis) |
PF00072(Response_reg)PF03861(ANTAR) | 5 | LEU A 61ILE A 25ILE A 118VAL A 16ILE A 63 | NoneIOD A 414 ( 4.4A)NoneNoneNone | 1.17A | 3d1yB-1sd5A:undetectable | 3d1yB-1sd5A:19.02 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1siv | SIV PROTEASE (Simianimmunodeficiencyvirus) |
PF00077(RVP) | 7 | ARG A 8LEU A 23ASP A 25GLY A 49ILE A 50PRO A 81ILE A 84 | None | 0.75A | 3d1yB-1sivA:18.3 | 3d1yB-1sivA:50.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1sr8 | COBALAMINBIOSYNTHESIS PROTEIN(CBID) (Archaeoglobusfulgidus) |
PF01888(CbiD) | 5 | LEU A 243ASP A 240ILE A 260GLY A 263ILE A 239 | None | 1.15A | 3d1yB-1sr8A:undetectable | 3d1yB-1sr8A:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tf1 | NEGATIVE REGULATOROF ALLANTOIN ANDGLYOXYLATEUTILIZATION OPERONS (Escherichiacoli) |
PF01614(IclR) | 5 | LEU A 180GLY A 46ILE A 45VAL A 16ILE A 176 | None | 1.14A | 3d1yB-1tf1A:undetectable | 3d1yB-1tf1A:18.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1tkk | SIMILAR TOCHLOROMUCONATECYCLOISOMERASE (Bacillussubtilis) |
PF02746(MR_MLE_N)PF13378(MR_MLE_C) | 5 | ILE A 354GLY A 44ILE A 36VAL A 32ILE A 33 | None | 1.09A | 3d1yB-1tkkA:undetectable | 3d1yB-1tkkA:17.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1vhe | AMINOPEPTIDASE/GLUCANASE HOMOLOG (Bacillussubtilis) |
PF05343(Peptidase_M42) | 5 | LEU A 350ILE A 305GLY A 235ILE A 317ILE A 232 | None | 1.18A | 3d1yB-1vheA:undetectable | 3d1yB-1vheA:14.66 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1wn1 | DIPEPTIDASE (Pyrococcushorikoshii) |
PF00557(Peptidase_M24)PF01321(Creatinase_N) | 5 | LEU A 167ILE A 182GLY A 217ILE A 227VAL A 188 | None | 1.04A | 3d1yB-1wn1A:undetectable | 3d1yB-1wn1A:14.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1xr4 | PUTATIVE CITRATELYASE ALPHACHAIN/CITRATE-ACPTRANSFERASE (Salmonellaenterica) |
PF04223(CitF) | 5 | LEU A 460ILE A 250ILE A 258VAL A 442ILE A 440 | None | 1.10A | 3d1yB-1xr4A:undetectable | 3d1yB-1xr4A:12.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2afv | COBALAMINBIOSYNTHESISPRECORRIN ISOMERASE (Leptospirainterrogans) |
PF02570(CbiC) | 5 | ILE A 194GLY A 165ILE A 139PRO A 160ILE A 136 | None | 0.91A | 3d1yB-2afvA:undetectable | 3d1yB-2afvA:18.58 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bmf | RNA HELICASE (Dengue virus) |
PF07652(Flavi_DEAD) | 5 | LEU A 204GLY A 311ILE A 281VAL A 208ILE A 207 | None | 1.13A | 3d1yB-2bmfA:undetectable | 3d1yB-2bmfA:13.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2bri | URIDYLATE KINASE (Pyrococcusfuriosus) |
PF00696(AA_kinase) | 5 | ASP A 206ILE A 214GLY A 216VAL A 201ILE A 202 | None | 1.14A | 3d1yB-2briA:undetectable | 3d1yB-2briA:19.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cev | PROTEIN (ARGINASE) ([Bacillus]caldovelox) |
PF00491(Arginase) | 5 | LEU A 46ILE A 101GLY A 104PRO A 92ILE A 7 | None | 1.03A | 3d1yB-2cevA:undetectable | 3d1yB-2cevA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cun | PHOSPHOGLYCERATEKINASE (Pyrococcushorikoshii) |
PF00162(PGK) | 5 | LEU A 316ILE A 376GLY A 357VAL A 343ILE A 347 | None | 0.81A | 3d1yB-2cunA:undetectable | 3d1yB-2cunA:15.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2cv6 | SEED STORAGE PROTEIN (Vigna radiata) |
PF00190(Cupin_1) | 5 | LEU A 296ILE A 287ILE A 284VAL A 336ILE A 294 | None | 1.14A | 3d1yB-2cv6A:undetectable | 3d1yB-2cv6A:14.46 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2fmb | EQUINE INFECTIOUSANEMIA VIRUSPROTEASE (Equineinfectiousanemia virus) |
PF00077(RVP) | 8 | ARG A 8LEU A 23ASP A 25ILE A 53GLY A 55PRO A 86VAL A 87ILE A 89 | LP1 A 201 (-3.5A)NoneLP1 A 201 (-2.3A)LP1 A 201 (-4.6A)LP1 A 201 (-3.4A)LP1 A 201 (-3.9A)LP1 A 201 ( 4.9A)LP1 A 201 (-4.2A) | 0.62A | 3d1yB-2fmbA:14.9 | 3d1yB-2fmbA:34.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2jir | PERIPLASMIC NITRATEREDUCTASE (Desulfovibriodesulfuricans) |
PF00384(Molybdopterin)PF01568(Molydop_binding)PF04879(Molybdop_Fe4S4) | 5 | LEU A 613ILE A 655ILE A 662VAL A 687ILE A 685 | None | 0.97A | 3d1yB-2jirA:undetectable | 3d1yB-2jirA:10.70 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2k4m | UPF0146 PROTEINMTH_1000 (Methanothermobacterthermautotrophicus) |
PF03686(UPF0146) | 5 | LEU A 92GLY A 43ILE A 96VAL A 39ILE A 93 | None | 0.98A | 3d1yB-2k4mA:undetectable | 3d1yB-2k4mA:18.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2nr7 | SECRETION ACTIVATORPROTEIN, PUTATIVE (Porphyromonasgingivalis) |
PF05838(Glyco_hydro_108)PF09374(PG_binding_3) | 5 | LEU A 134GLY A 102ILE A 103VAL A 87ILE A 138 | None | 0.75A | 3d1yB-2nr7A:undetectable | 3d1yB-2nr7A:22.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qu8 | PUTATIVE NUCLEOLARGTP-BINDING PROTEIN1 (Plasmodiumfalciparum) |
PF06858(NOG1) | 5 | ILE A 136GLY A 36ILE A 115VAL A 111ILE A 145 | None | 1.09A | 3d1yB-2qu8A:undetectable | 3d1yB-2qu8A:18.75 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2qw8 | EUGENOL SYNTHASE 1 (Ocimumbasilicum) |
PF05368(NmrA) | 5 | ARG A 106LEU A 108GLY A 26VAL A 78ILE A 80 | None | 1.16A | 3d1yB-2qw8A:undetectable | 3d1yB-2qw8A:15.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2r1v | DJ-1 (Homo sapiens) |
PF01965(DJ-1_PfpI) | 5 | LEU A 101GLY A 108ILE A 105VAL A 69ILE A 102 | None | 1.11A | 3d1yB-2r1vA:undetectable | 3d1yB-2r1vA:20.94 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2rkf | PROTEASE RETROPEPSIN (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 7 | ARG A 8LEU A 23ASP A 25GLY A 49ILE A 50PRO A 81ILE A 84 | AB1 A 501 ( 4.7A)NoneAB1 A 501 (-2.4A)AB1 A 501 (-3.5A)AB1 A 501 (-3.8A)AB1 A 501 (-4.2A)AB1 A 501 ( 4.2A) | 0.67A | 3d1yB-2rkfA:20.5 | 3d1yB-2rkfA:82.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2wfd | LEUCYL-TRNASYNTHETASE,CYTOPLASMIC (Homo sapiens) |
PF00133(tRNA-synt_1) | 5 | ILE A 287GLY A 315ILE A 314VAL A 307ILE A 357 | None | 1.08A | 3d1yB-2wfdA:undetectable | 3d1yB-2wfdA:21.52 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2y23 | MYOMESIN (Homo sapiens) |
PF07679(I-set) | 5 | ASP A1401GLY A1409ILE A1410VAL A1428ILE A1389 | None | 0.82A | 3d1yB-2y23A:undetectable | 3d1yB-2y23A:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2zj4 | GLUCOSAMINE--FRUCTOSE-6-PHOSPHATEAMINOTRANSFERASE[ISOMERIZING] 1 (Homo sapiens) |
PF01380(SIS) | 5 | ILE A 634ILE A 592PRO A 615VAL A 588ILE A 589 | None | 0.98A | 3d1yB-2zj4A:undetectable | 3d1yB-2zj4A:15.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3b8y | ENDO-PECTATE LYASE (Dickeyachrysanthemi) |
PF03211(Pectate_lyase) | 5 | LEU A 153ILE A 206GLY A 209ILE A 188ILE A 175 | None | 1.12A | 3d1yB-3b8yA:undetectable | 3d1yB-3b8yA:17.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3clj | PROTEIN NRD1 (Saccharomycescerevisiae) |
PF04818(CTD_bind) | 5 | LEU A 108GLY A 73ILE A 72VAL A 104ILE A 105 | None | 1.00A | 3d1yB-3cljA:undetectable | 3d1yB-3cljA:20.38 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3e9k | KYNURENINASE (Homo sapiens) |
PF00266(Aminotran_5) | 5 | LEU A 133ASP A 113ILE A 331GLY A 307ILE A 323 | None | 1.14A | 3d1yB-3e9kA:undetectable | 3d1yB-3e9kA:12.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3euj | CHROMOSOME PARTITIONPROTEIN MUKB, LINKER ([Haemophilus]ducreyi) |
PF04310(MukB)PF13558(SbcCD_C) | 5 | LEU A1290GLY A1396ILE A1399VAL A1301ILE A1293 | None | 1.16A | 3d1yB-3eujA:undetectable | 3d1yB-3eujA:12.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3i0m | DNA REPAIR ANDTELOMERE MAINTENANCEPROTEIN NBS1 (Schizosaccharomycespombe) |
PF00498(FHA) | 5 | ILE A 52GLY A 137ILE A 138VAL A 191ILE A 17 | None | 0.97A | 3d1yB-3i0mA:undetectable | 3d1yB-3i0mA:16.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3lun | ULILYSIN (Methanosarcinaacetivorans) |
PF05572(Peptidase_M43) | 5 | LEU A 171GLY A 211ILE A 93VAL A 69ILE A 173 | None | 1.10A | 3d1yB-3lunA:undetectable | 3d1yB-3lunA:17.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3moy | PROBABLE ENOYL-COAHYDRATASE (Mycolicibacteriumsmegmatis) |
PF00378(ECH_1) | 5 | ILE A 198GLY A 52ILE A 51VAL A 56ILE A 99 | None | 1.11A | 3d1yB-3moyA:undetectable | 3d1yB-3moyA:14.62 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mws | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 7 | ARG A 8LEU A 23ILE A 47GLY A 49ILE A 50PRO A 81VAL A 82 | None | 0.82A | 3d1yB-3mwsA:19.4 | 3d1yB-3mwsA:78.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3mws | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 8 | LEU A 23ASP A 25ILE A 47GLY A 49ILE A 50PRO A 81VAL A 82ILE A 84 | None | 0.67A | 3d1yB-3mwsA:19.4 | 3d1yB-3mwsA:78.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3qo6 | PROTEASE DO-LIKE 1,CHLOROPLASTIC (Arabidopsisthaliana) |
PF13180(PDZ_2)PF13365(Trypsin_2) | 5 | ILE A 236GLY A 284ILE A 296VAL A 221ILE A 219 | None | 1.16A | 3d1yB-3qo6A:undetectable | 3d1yB-3qo6A:17.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3rv6 | ISOCHORISMATESYNTHASE/ISOCHORISMATE-PYRUVATE LYASEMBTI (Mycobacteriumtuberculosis) |
PF00425(Chorismate_bind) | 5 | ARG A 376ASP A 378GLY A 421ILE A 422ILE A 374 | NoneNoneVAE A 451 ( 4.2A)NoneNone | 1.17A | 3d1yB-3rv6A:undetectable | 3d1yB-3rv6A:13.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3sc3 | PUTATIVE DNAREPLICATIONREGULATOR HDA (Shewanellaamazonensis) |
PF00308(Bac_DnaA) | 5 | LEU A 166ILE A 68ILE A 39VAL A 51ILE A 54 | None | 1.18A | 3d1yB-3sc3A:undetectable | 3d1yB-3sc3A:16.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t32 | AMINOTRANSFERASE,CLASS I/II (Bacillusanthracis) |
PF00155(Aminotran_1_2) | 5 | ARG A 334LEU A 338ILE A 302VAL A 346ILE A 344 | None | 1.10A | 3d1yB-3t32A:undetectable | 3d1yB-3t32A:17.15 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3t3c | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 5 | LEU A 23ASP A 25ILE A 47GLY A 49ILE A 50 | SO4 A 101 (-4.2A)017 A 201 (-2.6A)None017 A 201 (-4.0A)017 A 201 (-3.3A) | 0.46A | 3d1yB-3t3cA:18.2 | 3d1yB-3t3cA:75.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3t7s | PUTATIVEMETHYLTRANSFERASE (Bacteroidesvulgatus) |
PF13649(Methyltransf_25) | 5 | LEU A 146ILE A 72GLY A 74ILE A 75VAL A 148 | None | 1.10A | 3d1yB-3t7sA:undetectable | 3d1yB-3t7sA:18.66 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ttp | HIV-1 PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 7 | ARG A 8LEU A 23ASP A 25GLY A 49ILE A 50PRO A 81ILE A 84 | 017 A 201 ( 4.8A)None017 A 201 (-2.6A)017 A 201 (-3.0A)017 A 201 (-3.3A)017 A 201 (-4.1A)017 A 201 (-4.7A) | 0.66A | 3d1yB-3ttpA:19.3 | 3d1yB-3ttpA:76.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3u7s | POL POLYPROTEIN (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 7 | ARG A 8LEU A 23ASP A 25ILE A 47GLY A 49ILE A 50PRO A 81 | NoneNone017 A 202 ( 2.5A)017 A 202 (-3.6A)017 A 202 (-2.9A)017 A 201 ( 3.5A)017 A 202 (-4.0A) | 0.62A | 3d1yB-3u7sA:19.9 | 3d1yB-3u7sA:76.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vb9 | UNCHARACTERIZEDPROTEIN VPA0735 (Vibrioparahaemolyticus) |
PF06742(DUF1214)PF06863(DUF1254) | 5 | LEU A 160GLY A 86PRO A 163VAL A 162ILE A 161 | None | 1.14A | 3d1yB-3vb9A:undetectable | 3d1yB-3vb9A:13.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3vzq | ACETOACETYL-COAREDUCTASE (Cupriavidusnecator) |
PF00106(adh_short) | 5 | LEU A 199GLY A 184ILE A 186VAL A 203ILE A 202 | None | 1.18A | 3d1yB-3vzqA:undetectable | 3d1yB-3vzqA:16.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4a9a | RIBOSOME-INTERACTINGGTPASE 1 (Saccharomycescerevisiae) |
PF01926(MMR_HSR1)PF02824(TGS)PF16897(MMR_HSR1_Xtn) | 5 | LEU A 145ILE A 122GLY A 72ILE A 149VAL A 68 | None | 0.81A | 3d1yB-4a9aA:undetectable | 3d1yB-4a9aA:15.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4avo | BETA-1,4-EXOCELLULASE (Thermobifidafusca) |
PF01341(Glyco_hydro_6) | 5 | LEU A 178GLY A 313ILE A 315VAL A 217ILE A 219 | None | 0.91A | 3d1yB-4avoA:undetectable | 3d1yB-4avoA:13.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ex9 | ALNA (Streptomycessp. CM020) |
PF04227(Indigoidine_A) | 5 | LEU A 9ILE A 87GLY A 108ILE A 110VAL A 68 | None | 1.07A | 3d1yB-4ex9A:undetectable | 3d1yB-4ex9A:15.49 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4fmz | INTERNALIN (Listeriamonocytogenes) |
PF12354(Internalin_N)PF12799(LRR_4)PF13855(LRR_8) | 5 | LEU A 343ILE A 356ILE A 310VAL A 339ILE A 340 | NoneEDO A 405 (-3.8A)NoneNoneNone | 1.03A | 3d1yB-4fmzA:undetectable | 3d1yB-4fmzA:17.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4h0o | ACETATE KINASE (Entamoebahistolytica) |
PF00871(Acetate_kinase) | 5 | LEU A 183GLY A 208ILE A 195VAL A 179ILE A 180 | None | 0.98A | 3d1yB-4h0oA:undetectable | 3d1yB-4h0oA:13.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4jwy | GLUTAMATE RECEPTORIONOTROPIC, NMDA 2D (Rattusnorvegicus) |
PF10613(Lig_chan-Glu_bd) | 5 | LEU A 264ASP A 260ILE A 112GLY A 246ILE A 117 | None | 1.07A | 3d1yB-4jwyA:undetectable | 3d1yB-4jwyA:18.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4kpo | NUCLEOSIDEN-RIBOHYDROLASE 3 (Zea mays) |
PF01156(IU_nuc_hydro) | 5 | ASP A 8ILE A 129ILE A 167PRO A 68ILE A 34 | CA A 401 (-3.1A)NoneNoneNoneNone | 1.17A | 3d1yB-4kpoA:undetectable | 3d1yB-4kpoA:18.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l4y | TRANSCRIPTIONALREGULATOR LSRR (Escherichiacoli) |
PF04198(Sugar-bind) | 5 | LEU A 84ILE A 207GLY A 209ILE A 210VAL A 87 | None | 1.07A | 3d1yB-4l4yA:undetectable | 3d1yB-4l4yA:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4l5i | TRANSCRIPTIONALREGULATOR LSRR (Escherichiacoli) |
PF04198(Sugar-bind) | 5 | LEU A 84ILE A 207GLY A 209ILE A 210VAL A 87 | None | 1.08A | 3d1yB-4l5iA:undetectable | 3d1yB-4l5iA:14.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lik | DNA PRIMASE SMALLSUBUNIT (Homo sapiens) |
PF01896(DNA_primase_S) | 5 | LEU A 336GLY A 164ILE A 110VAL A 339ILE A 334 | None | 0.87A | 3d1yB-4likA:undetectable | 3d1yB-4likA:11.51 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4lmp | ALANINEDEHYDROGENASE (Mycobacteriumtuberculosis) |
PF01262(AlaDh_PNT_C)PF05222(AlaDh_PNT_N) | 5 | LEU A 207GLY A 189ILE A 186VAL A 196ILE A 215 | None | 1.06A | 3d1yB-4lmpA:undetectable | 3d1yB-4lmpA:16.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4njv | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 7 | ARG A 8LEU A 23ASP A 25ILE A 47GLY A 49ILE A 50ILE A 84 | RIT A 500 (-3.2A)NoneRIT A 500 (-2.4A)RIT A 500 ( 4.5A)RIT A 500 (-3.4A)RIT A 500 (-4.3A)RIT A 500 (-4.3A) | 0.42A | 3d1yB-4njvA:20.0 | 3d1yB-4njvA:85.86 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4njv | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 7 | LEU A 23ASP A 25ILE A 47GLY A 49ILE A 50PRO A 81ILE A 84 | NoneRIT A 500 (-2.4A)RIT A 500 ( 4.5A)RIT A 500 (-3.4A)RIT A 500 (-4.3A)RIT A 500 (-3.9A)RIT A 500 (-4.3A) | 0.67A | 3d1yB-4njvA:20.0 | 3d1yB-4njvA:85.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4o7h | GLUTATHIONES-TRANSFERASE (Rhodospirillumrubrum) |
PF13410(GST_C_2)PF13417(GST_N_3) | 5 | LEU A 170ILE A 130PRO A 180VAL A 179ILE A 173 | None | 1.10A | 3d1yB-4o7hA:undetectable | 3d1yB-4o7hA:17.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4p9n | CARBOXYLESTERASE (Sulfolobusshibatae) |
PF07859(Abhydrolase_3) | 5 | ARG A 221LEU A 163ILE A 51GLY A 53VAL A 122 | None | 1.04A | 3d1yB-4p9nA:undetectable | 3d1yB-4p9nA:16.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4pxq | D-GLUCURONYL C5EPIMERASE B (Danio rerio) |
PF06662(C5-epim_C) | 6 | LEU A 322ASP A 325GLY A 308ILE A 309VAL A 276ILE A 289 | None | 1.15A | 3d1yB-4pxqA:undetectable | 3d1yB-4pxqA:11.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4qs9 | HEXOKINASE-1 (Arabidopsisthaliana) |
PF00349(Hexokinase_1)PF03727(Hexokinase_2) | 5 | LEU A 302ASP A 299GLY A 406ILE A 318ILE A 326 | None | 1.15A | 3d1yB-4qs9A:undetectable | 3d1yB-4qs9A:12.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4re2 | BETA-MANNOSIDASE/BETA-GLUCOSIDASE (Oryza sativa) |
PF00232(Glyco_hydro_1) | 5 | LEU A 438ILE A 410PRO A 466VAL A 455ILE A 454 | None | 1.10A | 3d1yB-4re2A:undetectable | 3d1yB-4re2A:11.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ydf | HTLV-1 PROTEASE (PrimateT-lymphotropicvirus 1) |
PF00077(RVP) | 5 | ARG A 10LEU A 30ASP A 32GLY A 58ILE A 100 | NoneNone4B1 A 201 (-2.9A)4B1 A 201 (-3.4A)4B1 A 201 (-4.8A) | 0.58A | 3d1yB-4ydfA:12.8 | 3d1yB-4ydfA:32.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ywl | CELL DIVISIONCONTROL PROTEIN 21 (Pyrococcusfuriosus) |
PF14551(MCM_N)PF17207(MCM_OB) | 5 | ILE A 187GLY A 205ILE A 206VAL A 214ILE A 249 | None | 0.92A | 3d1yB-4ywlA:undetectable | 3d1yB-4ywlA:17.84 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5awm | STRESS-ACTIVATEDPROTEIN KINASE JNK (Drosophilamelanogaster) |
PF00069(Pkinase) | 5 | LEU A 113ILE A 83GLY A 136VAL A 157ILE A 155 | None | 1.17A | 3d1yB-5awmA:undetectable | 3d1yB-5awmA:14.32 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5boe | ENOLASE (Staphylococcusaureus) |
PF00113(Enolase_C)PF03952(Enolase_N) | 5 | ILE A 384ILE A 347PRO A 38VAL A 37ILE A 118 | None | 1.14A | 3d1yB-5boeA:undetectable | 3d1yB-5boeA:15.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5dlq | EXPORTIN-4 (Mus musculus) |
no annotation | 5 | LEU B 608ILE B 578ILE B 660VAL B 604ILE B 605 | None | 1.11A | 3d1yB-5dlqB:undetectable | 3d1yB-5dlqB:6.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5g5n | LH3HEXON-INTERLACINGCAPSID PROTEIN (Snakeatadenovirus A) |
PF01696(Adeno_E1B_55K) | 5 | LEU A 49ILE A 86ILE A 83PRO A 37ILE A 68 | None | 1.18A | 3d1yB-5g5nA:undetectable | 3d1yB-5g5nA:14.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5kk5 | CRISPR-ASSOCIATEDENDONUCLEASE CPF1 (Acidaminococcussp. BV3L6) |
no annotation | 5 | LEU A 66ILE A 121GLY A 112ILE A 111VAL A 69 | None | 1.14A | 3d1yB-5kk5A:undetectable | 3d1yB-5kk5A:5.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5mz9 | - (-) |
no annotation | 5 | LEU A 552GLY A 387ILE A 385VAL A 547ILE A 395 | None | 1.11A | 3d1yB-5mz9A:undetectable | 3d1yB-5mz9A:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5nr1 | FTSZ-BINDING PROTEINFZLA (Caulobactervibrioides) |
PF00043(GST_C)PF13417(GST_N_3) | 5 | LEU A 176GLY A 139PRO A 186VAL A 185ILE A 179 | None | 0.99A | 3d1yB-5nr1A:undetectable | 3d1yB-5nr1A:17.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5t2z | PROTEASE (Humanimmunodeficiencyvirus 1) |
PF00077(RVP) | 8 | ARG A 8LEU A 23ASP A 25ILE A 47GLY A 49ILE A 50PRO A 81ILE A 84 | None | 0.68A | 3d1yB-5t2zA:20.1 | 3d1yB-5t2zA:81.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5t5i | TUNGSTENFORMYLMETHANOFURANDEHYDROGENASESUBUNIT FWDG (Methanothermobacterwolfeii) |
PF12838(Fer4_7) | 5 | LEU G 60ILE G 76PRO G 23VAL G 24ILE G 45 | NoneSF4 G 101 ( 3.8A)NoneNoneSF4 G 102 ( 3.9A) | 1.02A | 3d1yB-5t5iG:undetectable | 3d1yB-5t5iG:25.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5vc2 | SERINEHYDROXYMETHYLTRANSFERASE (Helicobacterpylori) |
PF00464(SHMT) | 5 | LEU A 195ASP A 197GLY A 234ILE A 235VAL A 102 | None | 1.17A | 3d1yB-5vc2A:undetectable | 3d1yB-5vc2A:13.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5wka | BETA-GLUCOSIDASE (metagenome) |
no annotation | 5 | LEU A 418ILE A 390PRO A 446VAL A 435ILE A 434 | None | 1.13A | 3d1yB-5wkaA:undetectable | 3d1yB-5wkaA:22.99 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5xir | HEAT SHOCK 70 KDAPROTEIN 1A (Homo sapiens) |
no annotation | 5 | LEU A 22ILE A 41GLY A 105PRO A 19ILE A 35 | None | 1.13A | 3d1yB-5xirA:undetectable | 3d1yB-5xirA:20.79 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6fiv | RETROPEPSIN (Felineimmunodeficiencyvirus) |
PF00077(RVP) | 5 | ARG A 13LEU A 28ASP A 30GLY A 58VAL A 99 | NoneNone3TL A 201 (-3.5A)3TL A 201 (-3.4A)None | 0.47A | 3d1yB-6fivA:15.8 | 3d1yB-6fivA:30.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6fml | INO80 (Chaetomiumthermophilum) |
no annotation | 5 | LEU G1190ILE G 991GLY G 993ILE G 994ILE G1193 | None | 1.10A | 3d1yB-6fmlG:undetectable | 3d1yB-6fmlG:18.37 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g43 | PUTATIVE MAJORCAPSID PROTEIN (Cafeteriavirus-dependentmavirus) |
no annotation | 5 | ILE A 262GLY A 51ILE A 52PRO A 104VAL A 105 | None | 1.10A | 3d1yB-6g43A:undetectable | 3d1yB-6g43A:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6g45 | PUTATIVE MAJORCAPSID PROTEIN (Cafeteriavirus-dependentmavirus) |
no annotation | 5 | ILE A 262GLY A 51ILE A 52PRO A 104VAL A 105 | None | 1.02A | 3d1yB-6g45A:undetectable | 3d1yB-6g45A:17.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6gdg | TRXA,ADENOSINERECEPTOR A2A (Escherichiacoli;Homo sapiens) |
no annotation | 5 | LEU A 241ILE A 98ILE A 92VAL A 283ILE A 287 | None | 1.14A | 3d1yB-6gdgA:undetectable | 3d1yB-6gdgA:19.80 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6upj | HIV-2 PROTEASE (Humanimmunodeficiencyvirus 2) |
PF00077(RVP) | 5 | ARG A 8ASP A 25GLY A 49ILE A 50ILE A 84 | NoneNIU A 100 (-2.8A)NIU A 100 ( 3.8A)NIU A 100 (-3.9A)None | 0.84A | 3d1yB-6upjA:17.8 | 3d1yB-6upjA:48.48 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6upj | HIV-2 PROTEASE (Humanimmunodeficiencyvirus 2) |
PF00077(RVP) | 6 | LEU A 23ASP A 25GLY A 49ILE A 50PRO A 81ILE A 84 | NoneNIU A 100 (-2.8A)NIU A 100 ( 3.8A)NIU A 100 (-3.9A)NoneNone | 0.89A | 3d1yB-6upjA:17.8 | 3d1yB-6upjA:48.48 |