SIMILAR PATTERNS OF AMINO ACIDS FOR 3CYX_A_ROCA201_4

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1axd GLUTATHIONE
S-TRANSFERASE I

(Zea mays) 		PF00043
(GST_C)
PF02798
(GST_N) 		4 LEU A 110
ASP A 133
VAL A 117
THR A 178
 None
 1.00A 3cyxB-1axdA:
undetectable		 3cyxB-1axdA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1e6w SHORT CHAIN
3-HYDROXYACYL-COA
DEHYDROGENASE

(Rattus
norvegicus) 		PF00106
(adh_short) 		4 LEU A  39
ASP A  86
VAL A  89
THR A  26
 None
 1.27A 3cyxB-1e6wA:
0.0		 3cyxB-1e6wA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ezv UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN 2

(Saccharomyces
cerevisiae) 		PF00675
(Peptidase_M16) 		4 LEU B 264
ASP B 345
VAL B 255
THR B 321
 None
 1.21A 3cyxB-1ezvB:
0.0		 3cyxB-1ezvB:
14.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gnx BETA-GLUCOSIDASE

(Streptomyces
sp.) 		PF00232
(Glyco_hydro_1) 		4 LEU A 234
ASP A 302
VAL A 380
THR A 382
 None
 1.20A 3cyxB-1gnxA:
undetectable		 3cyxB-1gnxA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1gvf TAGATOSE-BISPHOSPHAT
E ALDOLASE AGAY

(Escherichia
coli) 		PF01116
(F_bP_aldolase) 		4 LEU A 135
ASP A 202
VAL A 169
THR A 167
 None
 1.12A 3cyxB-1gvfA:
undetectable		 3cyxB-1gvfA:
15.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 LEU A  23
ASP A  29
VAL A  32
THR A  80
 A79  A 800 ( 3.8A)
A79  A 800 (-2.8A)
A79  A 800 ( 4.4A)
None
 0.63A 3cyxB-1hvcA:
14.0		 3cyxB-1hvcA:
46.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1hvc HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 LEU A  23
ASP A  29
VAL A  32
THR A  80
 A79  A 800 ( 4.0A)
A79  A 800 (-2.7A)
A79  A 800 ( 4.3A)
None
 0.48A 3cyxB-1hvcA:
14.0		 3cyxB-1hvcA:
46.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ile ISOLEUCYL-TRNA
SYNTHETASE

(Thermus
thermophilus) 		PF00133
(tRNA-synt_1)
PF08264
(Anticodon_1) 		4 LEU A 329
ASP A 443
VAL A 178
THR A 401
 None
 1.21A 3cyxB-1ileA:
0.0		 3cyxB-1ileA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jzo THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBC

(Escherichia
coli) 		PF10411
(DsbC_N)
PF13098
(Thioredoxin_2) 		4 LEU A 173
ASP A  18
VAL A  36
THR A  63
 None
 1.07A 3cyxB-1jzoA:
0.0		 3cyxB-1jzoA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1pn3 GLYCOSYLTRANSFERASE
GTFA

(Amycolatopsis
orientalis) 		PF03033
(Glyco_transf_28) 		4 LEU A 101
ASP A  84
VAL A 108
THR A   6
 None
 1.27A 3cyxB-1pn3A:
undetectable		 3cyxB-1pn3A:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1so8 3-HYDROXYACYL-COA
DEHYDROGENASE TYPE
II

(Homo sapiens) 		PF00106
(adh_short) 		4 LEU A  39
ASP A  86
VAL A  89
THR A  26
 None
 1.16A 3cyxB-1so8A:
undetectable		 3cyxB-1so8A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1spx SHORT-CHAIN
REDUCTASE FAMILY
MEMBER (5L265)

(Caenorhabditis
elegans) 		PF13561
(adh_short_C2) 		4 LEU A  77
ASP A  66
VAL A  63
THR A  34
 None
 1.16A 3cyxB-1spxA:
undetectable		 3cyxB-1spxA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1upx HYDROXYLAMINE
REDUCTASE

(Desulfovibrio
desulfuricans) 		PF03063
(Prismane) 		4 LEU A 178
ASP A  35
VAL A  40
THR A  91
 None
 1.16A 3cyxB-1upxA:
undetectable		 3cyxB-1upxA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1v8b ADENOSYLHOMOCYSTEINA
SE

(Plasmodium
falciparum) 		PF00670
(AdoHcyase_NAD)
PF05221
(AdoHcyase) 		4 LEU A 218
ASP A 129
VAL A 197
THR A 139
 None
 1.01A 3cyxB-1v8bA:
undetectable		 3cyxB-1v8bA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vpx PROTEIN
(TRANSALDOLASE (EC
2.2.1.2))

(Thermotoga
maritima) 		PF00923
(TAL_FSA) 		4 LEU A  73
ASP A  48
VAL A  54
THR A  27
 None
 1.18A 3cyxB-1vpxA:
undetectable		 3cyxB-1vpxA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1vqr HYPOTHETICAL PROTEIN
CJ0248

(Campylobacter
jejuni) 		PF08668
(HDOD) 		4 LEU A  51
ASP A  93
VAL A  90
THR A  22
 None
 0.99A 3cyxB-1vqrA:
undetectable		 3cyxB-1vqrA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1w27 PHENYLALANINE
AMMONIA-LYASE 1

(Petroselinum
crispum) 		PF00221
(Lyase_aromatic) 		4 LEU A 641
ASP A 580
VAL A 634
THR A 535
 None
 1.05A 3cyxB-1w27A:
undetectable		 3cyxB-1w27A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1xfg GLUCOSAMINE--FRUCTOS
E-6-PHOSPHATE
AMINOTRANSFERASE
[ISOMERIZING]

(Escherichia
coli) 		PF13522
(GATase_6) 		4 LEU A 130
ASP A 162
VAL A  95
THR A 158
 None
 1.21A 3cyxB-1xfgA:
undetectable		 3cyxB-1xfgA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2b5m DAMAGE-SPECIFIC DNA
BINDING PROTEIN 1

(Homo sapiens) 		PF03178
(CPSF_A)
PF10433
(MMS1_N) 		4 LEU A  32
ASP A 318
VAL A  43
THR A  24
 None
 1.31A 3cyxB-2b5mA:
undetectable		 3cyxB-2b5mA:
6.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cxe RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Pyrococcus
horikoshii) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 LEU A 351
ASP A 391
VAL A 375
THR A 157
 None
 1.20A 3cyxB-2cxeA:
undetectable		 3cyxB-2cxeA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gm3 UNKNOWN PROTEIN

(Arabidopsis
thaliana) 		PF00582
(Usp) 		4 LEU A  50
ASP A 126
VAL A 129
THR A  34
 None
 1.30A 3cyxB-2gm3A:
undetectable		 3cyxB-2gm3A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gnp TRANSCRIPTIONAL
REGULATOR

(Streptococcus
pneumoniae) 		PF04198
(Sugar-bind) 		4 LEU A 293
ASP A 317
VAL A 286
THR A 307
 None
 1.22A 3cyxB-2gnpA:
undetectable		 3cyxB-2gnpA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2gwr DNA-BINDING RESPONSE
REGULATOR MTRA

(Mycobacterium
tuberculosis) 		PF00072
(Response_reg)
PF00486
(Trans_reg_C) 		4 LEU A  54
ASP A  13
VAL A  34
THR A  22
 None
CA  A2644 (-3.2A)
None
None
 1.17A 3cyxB-2gwrA:
undetectable		 3cyxB-2gwrA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2htm THIAZOLE
BIOSYNTHESIS PROTEIN
THIG

(Thermus
thermophilus) 		PF05690
(ThiG) 		4 LEU A  97
ASP A 134
VAL A 149
THR A 146
 None
 0.98A 3cyxB-2htmA:
undetectable		 3cyxB-2htmA:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2hvq HYPOTHETICAL 37.6
KDA PROTEIN IN
GP24-HOC INTERGENIC
REGION

(Escherichia
virus T4) 		PF09414
(RNA_ligase) 		4 LEU A 264
ASP A 180
VAL A 270
THR A 289
 None
 1.26A 3cyxB-2hvqA:
undetectable		 3cyxB-2hvqA:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2j6h GLUCOSAMINE-FRUCTOSE
-6-PHOSPHATE
AMINOTRANSFERASE

(Escherichia
coli) 		PF01380
(SIS)
PF13522
(GATase_6) 		4 LEU A 130
ASP A 162
VAL A  95
THR A 158
 None
 1.28A 3cyxB-2j6hA:
undetectable		 3cyxB-2j6hA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2mma MONOTHIOL
GLUTAREDOXIN-S14,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00462
(Glutaredoxin) 		4 LEU A 110
ASP A 116
VAL A 103
THR A 154
 None
 1.24A 3cyxB-2mmaA:
undetectable		 3cyxB-2mmaA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2nxf PUTATIVE DIMETAL
PHOSPHATASE

(Danio rerio) 		PF00149
(Metallophos) 		4 LEU A 301
ASP A  89
VAL A  52
THR A 298
 None
None
EOH  A 502 (-4.7A)
None
 1.29A 3cyxB-2nxfA:
undetectable		 3cyxB-2nxfA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1s 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE

(Escherichia
coli) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
PF13292
(DXP_synthase_N) 		4 LEU A 437
ASP A 539
VAL A 569
THR A 555
 None
 1.27A 3cyxB-2o1sA:
undetectable		 3cyxB-2o1sA:
10.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o1x 1-DEOXY-D-XYLULOSE-5
-PHOSPHATE SYNTHASE

(Deinococcus
radiodurans) 		PF02779
(Transket_pyr)
PF02780
(Transketolase_C)
PF13292
(DXP_synthase_N) 		4 LEU A 440
ASP A 542
VAL A 572
THR A 558
 None
 1.16A 3cyxB-2o1xA:
undetectable		 3cyxB-2o1xA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2p3e DIAMINOPIMELATE
DECARBOXYLASE

(Aquifex
aeolicus) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 LEU A 316
ASP A 342
VAL A 309
THR A 293
 None
 1.22A 3cyxB-2p3eA:
undetectable		 3cyxB-2p3eA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2pz0 GLYCEROPHOSPHORYL
DIESTER
PHOSPHODIESTERASE

(Caldanaerobacter
subterraneus) 		PF03009
(GDPD) 		4 LEU A  84
ASP A  46
VAL A  56
THR A  50
 None
CA  A 501 (-2.8A)
None
None
 1.29A 3cyxB-2pz0A:
undetectable		 3cyxB-2pz0A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qiw PEP PHOSPHONOMUTASE

(Corynebacterium
glutamicum) 		PF13714
(PEP_mutase) 		4 LEU A 102
ASP A  85
VAL A  71
THR A  75
 None
 1.31A 3cyxB-2qiwA:
undetectable		 3cyxB-2qiwA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2x60 MANNOSE-1-PHOSPHATE
GUANYLYLTRANSFERASE

(Thermotoga
maritima) 		PF00483
(NTP_transferase) 		4 LEU A 135
ASP A 100
VAL A 103
THR A  94
 None
 1.20A 3cyxB-2x60A:
undetectable		 3cyxB-2x60A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xfg ENDOGLUCANASE 1

(Ruminiclostridium
thermocellum) 		PF00759
(Glyco_hydro_9) 		4 LEU A 216
ASP A 234
VAL A 221
THR A 267
 None
 1.27A 3cyxB-2xfgA:
undetectable		 3cyxB-2xfgA:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xqy ENVELOPE
GLYCOPROTEIN H

(Suid
alphaherpesvirus
1) 		PF02489
(Herpes_glycop_H)
PF17488
(Herpes_glycoH_C) 		4 LEU A 383
ASP A 373
VAL A 359
THR A 396
 None
 1.30A 3cyxB-2xqyA:
undetectable		 3cyxB-2xqyA:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z99 PUTATIVE
UNCHARACTERIZED
PROTEIN

(Mycobacterium
tuberculosis) 		PF04079
(SMC_ScpB) 		4 LEU A  63
ASP A  26
VAL A  31
THR A  52
 None
 1.28A 3cyxB-2z99A:
undetectable		 3cyxB-2z99A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2zau SELENIDE, WATER
DIKINASE

(Aquifex
aeolicus) 		PF00586
(AIRS)
PF02769
(AIRS_C) 		4 LEU A 177
ASP A  68
VAL A  65
THR A 294
 None
 1.00A 3cyxB-2zauA:
undetectable		 3cyxB-2zauA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3a5v ALPHA-GALACTOSIDASE

(Umbelopsis
vinacea) 		PF16499
(Melibiase_2) 		4 LEU A 388
ASP A 296
VAL A 290
THR A 259
 None
1PG  A 851 (-4.3A)
None
None
 1.32A 3cyxB-3a5vA:
undetectable		 3cyxB-3a5vA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3asu SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE SDR

(Escherichia
coli) 		PF00106
(adh_short) 		4 LEU A  37
ASP A  46
VAL A  27
THR A  17
 None
 1.15A 3cyxB-3asuA:
undetectable		 3cyxB-3asuA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3d4o DIPICOLINATE
SYNTHASE SUBUNIT A

(Bacillus
halodurans) 		PF01262
(AlaDh_PNT_C)
PF16924
(DpaA_N) 		4 LEU A 162
ASP A 126
VAL A 165
THR A 219
 None
None
TAR  A 295 ( 3.8A)
None
 1.26A 3cyxB-3d4oA:
undetectable		 3cyxB-3d4oA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3esh PROTEIN SIMILAR TO
METAL-DEPENDENT
HYDROLASE

(Staphylococcus
aureus) 		PF00753
(Lactamase_B) 		4 LEU A 272
ASP A 268
VAL A 258
THR A 211
 None
 1.26A 3cyxB-3eshA:
undetectable		 3cyxB-3eshA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3fxg RHAMNONATE
DEHYDRATASE

(Fusarium
graminearum) 		PF02746
(MR_MLE_N)
PF13378
(MR_MLE_C) 		4 LEU A 308
ASP A 297
VAL A 321
THR A 340
 None
 1.24A 3cyxB-3fxgA:
undetectable		 3cyxB-3fxgA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3gfm 146AA LONG
HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR

(Sulfurisphaera
tokodaii) 		PF13463
(HTH_27) 		4 LEU A  93
ASP A  72
VAL A  80
THR A  46
 None
 1.26A 3cyxB-3gfmA:
undetectable		 3cyxB-3gfmA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3igf ALL4481 PROTEIN

(Nostoc sp. PCC
7120) 		PF02374
(ArsA_ATPase) 		4 LEU A 226
ASP A 135
VAL A 231
THR A 221
 None
 1.14A 3cyxB-3igfA:
undetectable		 3cyxB-3igfA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE

(Thermococcus
kodakarensis) 		PF00016
(RuBisCO_large)
PF02788
(RuBisCO_large_N) 		4 LEU A 370
ASP A 191
VAL A 160
THR A 394
 None
MG  A 500 ( 3.0A)
None
None
 1.22A 3cyxB-3kdnA:
undetectable		 3cyxB-3kdnA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lgx D-ALANINE--POLY(PHOS
PHORIBITOL) LIGASE
SUBUNIT 1

(Streptococcus
pyogenes) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 LEU A 118
ASP A  80
VAL A  54
THR A  65
 None
 0.81A 3cyxB-3lgxA:
undetectable		 3cyxB-3lgxA:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3mos TRANSKETOLASE

(Homo sapiens) 		PF00456
(Transketolase_N)
PF02779
(Transket_pyr)
PF02780
(Transketolase_C) 		4 LEU A 434
ASP A 541
VAL A 572
THR A 558
 None
 1.15A 3cyxB-3mosA:
undetectable		 3cyxB-3mosA:
12.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3mws HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 LEU A  23
ASP A  29
VAL A  32
THR A  80
 None
 0.44A 3cyxB-3mwsA:
19.7		 3cyxB-3mwsA:
78.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3on6 UNCHARACTERIZED
PROTEIN

(Bacteroides
ovatus) 		PF06824
(Glyco_hydro_125) 		4 LEU A 343
ASP A 346
VAL A 375
THR A 371
 None
 1.20A 3cyxB-3on6A:
undetectable		 3cyxB-3on6A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p2c PUTATIVE GLYCOSYL
HYDROLASE

(Bacteroides
ovatus) 		PF06824
(Glyco_hydro_125) 		4 LEU A 349
ASP A 352
VAL A 381
THR A 377
 None
 1.19A 3cyxB-3p2cA:
undetectable		 3cyxB-3p2cA:
12.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pvd CAPSID

(Norwalk virus) 		PF08435
(Calici_coat_C) 		4 LEU A 449
ASP A 269
VAL A 455
THR A 276
 None
 1.21A 3cyxB-3pvdA:
undetectable		 3cyxB-3pvdA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3pw3 AMINOPEPTIDASE C

(Parabacteroides
distasonis) 		PF03051
(Peptidase_C1_2) 		4 LEU A 186
ASP A  91
VAL A 178
THR A 149
 None
 1.26A 3cyxB-3pw3A:
undetectable		 3cyxB-3pw3A:
12.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3t3c HIV-1 PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 LEU A  23
ASP A  29
VAL A  32
THR A  80
 SO4  A 101 (-4.2A)
017  A 201 (-3.5A)
None
None
 0.47A 3cyxB-3t3cA:
18.4		 3cyxB-3t3cA:
73.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tkt CYTOCHROME P450

(Novosphingobium
aromaticivorans) 		PF00067
(p450) 		4 LEU A 172
ASP A 238
VAL A 243
THR A 119
 None
 1.25A 3cyxB-3tktA:
undetectable		 3cyxB-3tktA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3tx8 SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE

(Corynebacterium
glutamicum) 		PF01546
(Peptidase_M20)
PF07687
(M20_dimer) 		4 LEU A 162
ASP A 358
VAL A 110
THR A 114
 None
 1.30A 3cyxB-3tx8A:
undetectable		 3cyxB-3tx8A:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ty4 PROBABLE
HOMOISOCITRATE
DEHYDROGENASE

(Schizosaccharomyces
pombe) 		PF00180
(Iso_dh) 		4 LEU A  11
ASP A  15
VAL A  21
THR A 305
 None
 1.09A 3cyxB-3ty4A:
undetectable		 3cyxB-3ty4A:
11.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vab DIAMINOPIMELATE
DECARBOXYLASE 1

(Brucella
melitensis) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 LEU A 313
ASP A 341
VAL A 306
THR A 290
 None
EDO  A 424 (-3.8A)
None
None
 1.10A 3cyxB-3vabA:
undetectable		 3cyxB-3vabA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4bax GLUTAMINE SYNTHETASE

(Streptomyces
coelicolor) 		PF00120
(Gln-synt_C)
PF03951
(Gln-synt_N) 		4 LEU A 196
ASP A 337
VAL A 330
THR A  98
 None
 1.30A 3cyxB-4baxA:
undetectable		 3cyxB-4baxA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fh8 ACEPRX-1

(Ancylostoma
ceylanicum) 		PF00578
(AhpC-TSA)
PF10417
(1-cysPrx_C) 		4 LEU A  66
ASP A 131
VAL A  37
THR A 153
 None
 1.19A 3cyxB-4fh8A:
undetectable		 3cyxB-4fh8A:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4gys ALLOPHANATE
HYDROLASE

(Granulibacter
bethesdensis) 		PF01425
(Amidase) 		4 LEU A 192
ASP A  98
VAL A 197
THR A 167
 None
 1.27A 3cyxB-4gysA:
undetectable		 3cyxB-4gysA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4haq GH7 FAMILY PROTEIN

(Limnoria
quadripunctata) 		PF00840
(Glyco_hydro_7) 		4 LEU A  34
ASP A  52
VAL A  93
THR A  97
 None
 1.22A 3cyxB-4haqA:
undetectable		 3cyxB-4haqA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4jb3 HALOACID
DEHALOGENASE-LIKE
HYDROLASE

(Bacteroides
thetaiotaomicron) 		PF13419
(HAD_2) 		4 LEU A 183
ASP A 159
VAL A 162
THR A 167
 None
 1.31A 3cyxB-4jb3A:
undetectable		 3cyxB-4jb3A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4kw6 PEROXIREDOXIN-1

(Ancylostoma
ceylanicum) 		PF00578
(AhpC-TSA) 		4 LEU A  66
ASP A 131
VAL A  37
THR A 153
 None
 1.20A 3cyxB-4kw6A:
undetectable		 3cyxB-4kw6A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n01 PERIPLASMIC BINDING
PROTEIN

(Veillonella
parvula) 		PF01497
(Peripla_BP_2) 		4 LEU A  97
ASP A  81
VAL A 104
THR A  86
 None
 1.22A 3cyxB-4n01A:
undetectable		 3cyxB-4n01A:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nbq POLYRIBONUCLEOTIDE
NUCLEOTIDYLTRANSFERA
SE

(Coxiella
burnetii) 		PF00013
(KH_1)
PF00575
(S1)
PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		4 LEU A 371
ASP A 167
VAL A 123
THR A  37
 None
 1.30A 3cyxB-4nbqA:
undetectable		 3cyxB-4nbqA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nbv 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE PUTATIVE
SHORT-CHAIN
DEHYDROGENASES/REDUC
TASES (SDR) FAMILY
PROTEIN

(Cupriavidus
taiwanensis) 		PF13561
(adh_short_C2) 		4 LEU A  34
ASP A  84
VAL A  87
THR A  21
 None
 1.24A 3cyxB-4nbvA:
undetectable		 3cyxB-4nbvA:
15.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4njv PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 LEU A  23
ASP A  29
VAL A  32
THR A  80
 None
RIT  A 500 (-3.2A)
None
None
 0.56A 3cyxB-4njvA:
20.2		 3cyxB-4njvA:
83.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nnp LIPOPROTEIN

(Staphylococcus
aureus) 		PF01297
(ZnuA) 		4 LEU A  42
ASP A  55
VAL A  84
THR A 158
 None
 1.31A 3cyxB-4nnpA:
undetectable		 3cyxB-4nnpA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oht SUCCINATE-SEMIALDEHY
DE DEHYDROGENASE

(Streptococcus
pyogenes) 		PF00171
(Aldedh) 		4 LEU A  35
ASP A 197
VAL A  28
THR A 182
 None
 1.26A 3cyxB-4ohtA:
undetectable		 3cyxB-4ohtA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4oj2 AQUAPORIN-2

(Homo sapiens) 		PF00230
(MIP) 		4 LEU X 189
ASP X 200
VAL X 118
THR X 195
 None
 1.12A 3cyxB-4oj2X:
undetectable		 3cyxB-4oj2X:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pfs COBYRINIC ACID
A,C-DIAMIDE SYNTHASE

(Mycolicibacterium
smegmatis) 		PF13614
(AAA_31) 		4 LEU A  44
ASP A 150
VAL A  15
THR A  27
 None
 1.32A 3cyxB-4pfsA:
undetectable		 3cyxB-4pfsA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qlj BETA-GLUCOSIDASE 7

(Oryza sativa) 		PF00232
(Glyco_hydro_1) 		4 LEU A 242
ASP A 308
VAL A 383
THR A 385
 None
 1.24A 3cyxB-4qljA:
undetectable		 3cyxB-4qljA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4r10 PROTEIN HUMPBACK-2

(Caenorhabditis
elegans) 		PF00514
(Arm) 		4 LEU A 335
ASP A 375
VAL A 368
THR A 358
 None
 1.26A 3cyxB-4r10A:
undetectable		 3cyxB-4r10A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rlz CAPSID PROTEIN

(Norwalk virus) 		PF00915
(Calici_coat)
PF08435
(Calici_coat_C) 		4 LEU A 449
ASP A 267
VAL A 455
THR A 274
 None
 1.17A 3cyxB-4rlzA:
undetectable		 3cyxB-4rlzA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4rpd CAPSID PROTEIN

(Norwalk virus) 		PF08435
(Calici_coat_C) 		4 LEU A 447
ASP A 269
VAL A 453
THR A 276
 None
 1.20A 3cyxB-4rpdA:
undetectable		 3cyxB-4rpdA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xg1 DIAMINOPIMELATE
DECARBOXYLASE

(Psychromonas
ingrahamii) 		PF00278
(Orn_DAP_Arg_deC)
PF02784
(Orn_Arg_deC_N) 		4 LEU A 311
ASP A 342
VAL A 304
THR A 288
 None
 1.07A 3cyxB-4xg1A:
undetectable		 3cyxB-4xg1A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xhm THIOREDOXIN (TRX-3)

(Archaeoglobus
fulgidus) 		PF00085
(Thioredoxin) 		4 LEU A  29
ASP A  53
VAL A  50
THR A  43
 None
 1.15A 3cyxB-4xhmA:
undetectable		 3cyxB-4xhmA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ydo UNCHARACTERIZED
PROTEIN

(Candida
albicans) 		PF00432
(Prenyltrans) 		4 LEU B 381
ASP B 339
VAL B 345
THR B 313
 None
 0.97A 3cyxB-4ydoB:
undetectable		 3cyxB-4ydoB:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ywc TRANSCRIPTION FACTOR
MYC3

(Arabidopsis
thaliana) 		PF14215
(bHLH-MYC_N) 		4 LEU A  90
ASP A  94
VAL A 213
THR A 208
 None
 1.31A 3cyxB-4ywcA:
undetectable		 3cyxB-4ywcA:
17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4zqg 1-DEOXY-D-XYLULOSE
5-PHOSPHATE
REDUCTOISOMERASE

(Moraxella
catarrhalis) 		PF02670
(DXP_reductoisom)
PF08436
(DXP_redisom_C)
PF13288
(DXPR_C) 		4 LEU A  37
ASP A  98
VAL A 101
THR A  21
 None
 0.95A 3cyxB-4zqgA:
undetectable		 3cyxB-4zqgA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aho 5' EXONUCLEASE
APOLLO

(Homo sapiens) 		PF07522
(DRMBL) 		4 LEU A 144
ASP A  14
VAL A 298
THR A 147
 None
None
None
TLA  A1319 ( 4.7A)
 1.29A 3cyxB-5ahoA:
undetectable		 3cyxB-5ahoA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5aid MEP2

(Candida
albicans) 		PF00909
(Ammonium_transp) 		4 LEU A 355
ASP A 359
VAL A 304
THR A 308
 None
 1.27A 3cyxB-5aidA:
undetectable		 3cyxB-5aidA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5b4x REELIN

(Mus musculus) 		PF07974
(EGF_2) 		4 LEU A2379
ASP A2376
VAL A2373
THR A2450
 None
 1.27A 3cyxB-5b4xA:
undetectable		 3cyxB-5b4xA:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gzt CHITINASE

(Paenibacillus
sp. FPU-7) 		no annotation 4 LEU A 243
ASP A 231
VAL A 270
THR A 274
 None
 0.92A 3cyxB-5gztA:
undetectable		 3cyxB-5gztA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5hu6 HAPTOGLOBIN-HEMOGLOB
IN RECEPTOR

(Trypanosoma
brucei) 		no annotation 4 LEU D 157
ASP D 147
VAL D 247
THR D  69
 None
 1.26A 3cyxB-5hu6D:
undetectable		 3cyxB-5hu6D:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ip9 DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB1
DNA-DIRECTED RNA
POLYMERASE II
SUBUNIT RPB2

(Saccharomyces
cerevisiae) 		PF00562
(RNA_pol_Rpb2_6)
PF00623
(RNA_pol_Rpb1_2)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5)
PF04983
(RNA_pol_Rpb1_3)
PF04990
(RNA_pol_Rpb1_7)
PF04992
(RNA_pol_Rpb1_6)
PF04997
(RNA_pol_Rpb1_1)
PF04998
(RNA_pol_Rpb1_5)
PF05000
(RNA_pol_Rpb1_4) 		4 LEU B1030
ASP B 760
VAL B1023
THR A 669
 None
 0.96A 3cyxB-5ip9B:
undetectable		 3cyxB-5ip9B:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5j32 3-ISOPROPYLMALATE
DEHYDROGENASE 2,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF00180
(Iso_dh) 		4 LEU A  47
ASP A  51
VAL A  57
THR A 338
 None
 1.14A 3cyxB-5j32A:
undetectable		 3cyxB-5j32A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5k9z PUTATIVE SHORT-CHAIN
DEHYDROGENASE/REDUCT
ASE

(Paraburkholderia
xenovorans) 		PF13561
(adh_short_C2) 		4 LEU A  44
ASP A  90
VAL A  93
THR A  31
 None
 1.25A 3cyxB-5k9zA:
undetectable		 3cyxB-5k9zA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5kl0 PHOSPHOGLUCOMUTASE

(Xanthomonas
citri) 		PF00408
(PGM_PMM_IV)
PF02878
(PGM_PMM_I)
PF02879
(PGM_PMM_II)
PF02880
(PGM_PMM_III) 		4 LEU A 435
ASP A 427
VAL A 448
THR A 461
 None
 1.32A 3cyxB-5kl0A:
undetectable		 3cyxB-5kl0A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5lxv CARBOHYDRATE-BINDING
PROTEIN WP_009985128
SCAFFOLDIN C

(Ruminococcus
flavefaciens) 		PF00963
(Cohesin)
no annotation 		4 LEU B 904
ASP B 933
VAL B 911
THR A  69
 None
 1.15A 3cyxB-5lxvB:
undetectable		 3cyxB-5lxvB:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5omm CAPSID PROTEIN

(Norwalk virus) 		PF08435
(Calici_coat_C) 		4 LEU A 460
ASP A 269
VAL A 466
THR A 276
 None
 1.23A 3cyxB-5ommA:
undetectable		 3cyxB-5ommA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5sv9 BOR1P BORON
TRANSPORTER

(Saccharomyces
mikatae) 		PF00955
(HCO3_cotransp) 		4 LEU A 412
ASP A 197
VAL A 204
THR A 248
 None
 1.14A 3cyxB-5sv9A:
undetectable		 3cyxB-5sv9A:
13.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5t2z PROTEASE

(Human
immunodeficiency
virus 1) 		PF00077
(RVP) 		4 LEU A  23
ASP A  29
VAL A  32
THR A  80
 None
 0.39A 3cyxB-5t2zA:
20.3		 3cyxB-5t2zA:
79.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5w7m GLANDICOLINE B
O-METHYLTRANSFERASE
ROQN

(Penicillium
rubens) 		no annotation 4 LEU A  64
ASP A  82
VAL A  59
THR A  31
 None
SAH  A 301 (-2.9A)
SAH  A 301 (-4.5A)
None
 1.29A 3cyxB-5w7mA:
undetectable		 3cyxB-5w7mA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ysx -

(-) 		no annotation 4 LEU A 233
ASP A  48
VAL A 239
THR A  55
 None
 1.24A 3cyxB-5ysxA:
undetectable		 3cyxB-5ysxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5zzk MONOFUNCTIONAL
GLYCOSYLTRANSFERASE

(Staphylococcus
aureus) 		no annotation 4 LEU A 157
ASP A  68
VAL A 163
THR A 135
 None
 1.10A 3cyxB-5zzkA:
undetectable		 3cyxB-5zzkA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6daw NON-HEME IRON
HYDROXYLASE

(Streptomyces
lusitanus) 		no annotation 4 LEU A 162
ASP A  73
VAL A  95
THR A  19
 None
 1.24A 3cyxB-6dawA:
undetectable		 3cyxB-6dawA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ek9 -

(-) 		no annotation 4 LEU A 131
ASP A  82
VAL A  89
THR A  71
 None
None
None
CU1  A 214 (-3.6A)
 1.13A 3cyxB-6ek9A:
undetectable		 3cyxB-6ek9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6eoj PROTEIN CFT1

(Saccharomyces
cerevisiae) 		no annotation 4 LEU A 927
ASP A 878
VAL A 508
THR A 552
 None
 1.25A 3cyxB-6eojA:
undetectable		 3cyxB-6eojA:
6.67