SIMILAR PATTERNS OF AMINO ACIDS FOR 3CFL_A_5CHA693_1

List of similar pattern of amino acids derived from ASSAM search

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click link on the last column to view superposed patterns of amino acids in NGL viewer)
(Note that only 3-12 residue patterns can be used for ASSAM searches)
Filter list by:
Hit Macromolecule/
Organism		 Pfam Res. Interface HETATM RMSD Dali Z-score Seq. Identity (%) View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1biy LACTOFERRIN

(Bubalus bubalis) 		PF00405
(Transferrin) 		4 THR A 377
VAL A 516
GLY A 525
THR A 527
 None
 1.04A 3cflA-1biyA:
41.1		 3cflA-1biyA:
91.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1biy LACTOFERRIN

(Bubalus bubalis) 		PF00405
(Transferrin) 		4 THR A 430
VAL A 591
GLY A 662
THR A 663
 None
 0.57A 3cflA-1biyA:
41.1		 3cflA-1biyA:
91.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1dlp LECTIN SCAFET
PRECURSOR

(Hyacinthoides
hispanica) 		PF01453
(B_lectin) 		4 THR A 140
VAL A 195
GLY A 182
THR A 181
 None
 0.82A 3cflA-1dlpA:
0.0		 3cflA-1dlpA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1fgp FD GENE 3 PROTEIN

(Enterobacteria
phage fd) 		PF05357
(Phage_Coat_A) 		4 THR A  46
VAL A  19
GLY A  54
THR A  55
 None
 0.92A 3cflA-1fgpA:
0.0		 3cflA-1fgpA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1flo FLP RECOMBINASE

(Saccharomyces
cerevisiae) 		PF03930
(Flp_N)
PF05202
(Flp_C) 		4 THR A 224
VAL A 219
GLY A 190
THR A 185
 None
 0.70A 3cflA-1floA:
0.0		 3cflA-1floA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1hg0 L-ASPARAGINASE

(Dickeya
chrysanthemi) 		PF00710
(Asparaginase) 		4 THR A 312
VAL A 220
GLY A  67
THR A  66
 None
 1.09A 3cflA-1hg0A:
1.7		 3cflA-1hg0A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1igw ISOCITRATE LYASE

(Escherichia
coli) 		PF00463
(ICL) 		4 THR A 395
VAL A 403
GLY A  75
THR A  73
 None
 1.09A 3cflA-1igwA:
0.0		 3cflA-1igwA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1jye LACTOSE OPERON
REPRESSOR

(Escherichia
coli) 		PF13377
(Peripla_BP_3) 		4 THR A 229
VAL A 264
GLY A 272
THR A 288
 None
 1.02A 3cflA-1jyeA:
0.2		 3cflA-1jyeA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1lcy HTRA2 SERINE
PROTEASE

(Homo sapiens) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 THR A 138
VAL A 178
GLY A 174
THR A  62
 None
 0.86A 3cflA-1lcyA:
0.0		 3cflA-1lcyA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1oqw FIMBRIAL PROTEIN

(Pseudomonas
aeruginosa) 		PF00114
(Pilin)
PF07963
(N_methyl) 		4 THR A  45
VAL A  57
GLY A  74
THR A  61
 None
 1.02A 3cflA-1oqwA:
0.0		 3cflA-1oqwA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1qqj FUMARYLACETOACETATE
HYDROLASE

(Mus musculus) 		PF01557
(FAA_hydrolase)
PF09298
(FAA_hydrolase_N) 		4 THR A 393
VAL A 390
GLY A 170
THR A 171
 None
 1.03A 3cflA-1qqjA:
undetectable		 3cflA-1qqjA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1rc9 CYSTEINE-RICH
SECRETORY PROTEIN

(Trimeresurus
stejnegeri) 		PF00188
(CAP)
PF08562
(Crisp) 		4 THR A 159
VAL A  29
GLY A 164
THR A 165
 None
 1.08A 3cflA-1rc9A:
undetectable		 3cflA-1rc9A:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tlf LAC REPRESSOR

(Escherichia
coli) 		PF13377
(Peripla_BP_3) 		4 THR A 229
VAL A 264
GLY A 272
THR A 288
 None
 1.03A 3cflA-1tlfA:
undetectable		 3cflA-1tlfA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1tol PROTEIN (FUSION
PROTEIN CONSISTING
OF MINOR COAT
PROTEIN, GLYCINE
RICH LINKER, TOLA,
AND A HIS TAG)

(Escherichia
coli;
Escherichia
virus M13) 		PF05357
(Phage_Coat_A)
PF06519
(TolA) 		4 THR A  47
VAL A  20
GLY A  55
THR A  56
 None
 1.08A 3cflA-1tolA:
undetectable		 3cflA-1tolA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1uyp BETA-FRUCTOSIDASE

(Thermotoga
maritima) 		PF00251
(Glyco_hydro_32N)
PF08244
(Glyco_hydro_32C) 		4 THR A 263
VAL A 276
GLY A  13
THR A  12
 None
 0.86A 3cflA-1uypA:
undetectable		 3cflA-1uypA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cda GLUCOSE
DEHYDROGENASE

(Sulfolobus
solfataricus) 		PF08240
(ADH_N)
PF16912
(Glu_dehyd_C) 		4 THR A 336
VAL A 350
GLY A  40
THR A  41
 None
 1.01A 3cflA-2cdaA:
undetectable		 3cflA-2cdaA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2cvt RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE
LARGE CHAIN 1

(Saccharomyces
cerevisiae) 		PF00317
(Ribonuc_red_lgN)
PF02867
(Ribonuc_red_lgC)
PF03477
(ATP-cone) 		4 THR A 189
VAL A 484
GLY A 209
THR A 210
 None
 1.04A 3cflA-2cvtA:
undetectable		 3cflA-2cvtA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2do8 UPF0301 PROTEIN
HD_1794

([Haemophilus]
ducreyi) 		PF02622
(DUF179) 		4 THR A  45
VAL A  49
GLY A  83
THR A 108
 None
 1.10A 3cflA-2do8A:
undetectable		 3cflA-2do8A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ill TITIN

(Homo sapiens) 		PF07679
(I-set) 		4 THR A  27
VAL A  34
GLY A  88
THR A  89
 None
 1.06A 3cflA-2illA:
undetectable		 3cflA-2illA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2iq7 ENDOPOLYGALACTURONAS
E

(Colletotrichum
lupini) 		PF00295
(Glyco_hydro_28) 		4 THR A 213
VAL A 159
GLY A 187
THR A 186
 None
 0.93A 3cflA-2iq7A:
undetectable		 3cflA-2iq7A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2l1t UNCHARACTERIZED
PROTEIN

(Geobacter
sulfurreducens) 		no annotation 4 THR A  59
VAL A  66
GLY A  33
THR A  34
 None
 1.00A 3cflA-2l1tA:
undetectable		 3cflA-2l1tA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2o9r BETA-GLUCOSIDASE B

(Paenibacillus
polymyxa) 		PF00232
(Glyco_hydro_1) 		4 THR A  39
VAL A  47
GLY A 179
THR A 178
 None
 1.03A 3cflA-2o9rA:
undetectable		 3cflA-2o9rA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2paf LACTOSE OPERON
REPRESSOR

(Escherichia
coli) 		PF13377
(Peripla_BP_3) 		4 THR A 229
VAL A 264
GLY A 272
THR A 288
 None
 1.07A 3cflA-2pafA:
undetectable		 3cflA-2pafA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2py0 FIMBRIAL PROTEIN

(Pseudomonas
aeruginosa) 		PF00114
(Pilin) 		4 THR A  45
VAL A  57
GLY A  74
THR A  61
 None
 1.07A 3cflA-2py0A:
undetectable		 3cflA-2py0A:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2qve TYROSINE AMINOMUTASE

(Streptomyces
globisporus) 		PF00221
(Lyase_aromatic) 		4 THR A 141
VAL A  28
GLY A 212
THR A 211
 None
 0.91A 3cflA-2qveA:
undetectable		 3cflA-2qveA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2vz9 FATTY ACID SYNTHASE

(Sus scrofa) 		PF00107
(ADH_zinc_N)
PF00109
(ketoacyl-synt)
PF00698
(Acyl_transf_1)
PF02801
(Ketoacyl-synt_C)
PF08242
(Methyltransf_12)
PF08659
(KR)
PF14765
(PS-DH)
PF16197
(KAsynt_C_assoc) 		4 THR A1922
VAL A1929
GLY A1892
THR A1890
 None
 1.10A 3cflA-2vz9A:
undetectable		 3cflA-2vz9A:
9.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2w6d DYNAMIN FAMILY
PROTEIN

(Nostoc
punctiforme) 		PF00350
(Dynamin_N) 		4 THR A 565
VAL A 608
GLY A 556
THR A 553
 CPL  A1705 (-3.7A)
None
None
None
 1.09A 3cflA-2w6dA:
undetectable		 3cflA-2w6dA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2wek ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2

(Homo sapiens) 		PF00107
(ADH_zinc_N)
PF08240
(ADH_N) 		4 THR A 179
VAL A 241
GLY A 230
THR A 231
 None
 0.90A 3cflA-2wekA:
undetectable		 3cflA-2wekA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2xt4 MCBG-LIKE PROTEIN

(Xanthomonas
albilineans) 		PF00805
(Pentapeptide)
PF13599
(Pentapeptide_4) 		4 THR A 143
VAL A 120
GLY A 159
THR A 158
 None
 1.09A 3cflA-2xt4A:
undetectable		 3cflA-2xt4A:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2z22 PERIPLASMIC
PHOSPHATE-BINDING
PROTEIN

(Yersinia pestis) 		no annotation 4 THR X  74
VAL X 260
GLY X   6
THR X   5
 None
 1.03A 3cflA-2z22X:
5.8		 3cflA-2z22X:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ztu D(-)-3-HYDROXYBUTYRA
TE DEHYDROGENASE

(Pseudomonas
fragi) 		PF13561
(adh_short_C2) 		4 THR A 122
VAL A 162
GLY A 248
THR A 249
 None
 1.00A 3cflA-2ztuA:
undetectable		 3cflA-2ztuA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3cdi POLYNUCLEOTIDE
PHOSPHORYLASE

(Escherichia
coli) 		PF01138
(RNase_PH)
PF03725
(RNase_PH_C)
PF03726
(PNPase) 		4 THR A 376
VAL A 478
GLY A 380
THR A 381
 None
 0.96A 3cflA-3cdiA:
undetectable		 3cflA-3cdiA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dc8 DIHYDROPYRIMIDINASE

(Sinorhizobium
meliloti) 		PF01979
(Amidohydro_1) 		4 THR A 405
VAL A 440
GLY A  82
THR A  84
 None
 0.79A 3cflA-3dc8A:
undetectable		 3cflA-3dc8A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3dhv D-ALANINE-POLY(PHOSP
HORIBITOL) LIGASE

(Bacillus cereus) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C) 		4 THR A 265
VAL A 308
GLY A 305
THR A 304
 None
 0.99A 3cflA-3dhvA:
undetectable		 3cflA-3dhvA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3f44 PUTATIVE
MONOOXYGENASE

(Lactobacillus
acidophilus) 		PF03992
(ABM) 		4 THR A 101
VAL A  60
GLY A 156
THR A 157
 None
 1.06A 3cflA-3f44A:
undetectable		 3cflA-3f44A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3frn FLAGELLAR PROTEIN
FLGA

(Thermotoga
maritima) 		PF13144
(ChapFlgA) 		4 THR A 244
VAL A 278
GLY A 271
THR A 257
 None
 1.10A 3cflA-3frnA:
undetectable		 3cflA-3frnA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ga4 DOLICHYL-DIPHOSPHOOL
IGOSACCHARIDE-PROTEI
N
GLYCOSYLTRANSFERASE
SUBUNIT OST6

(Saccharomyces
cerevisiae) 		PF04756
(OST3_OST6) 		4 THR A  85
VAL A 103
GLY A  47
THR A  48
 None
 1.09A 3cflA-3ga4A:
undetectable		 3cflA-3ga4A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hag CAPSID PROTEIN

(Orthohepevirus
A) 		PF03014
(SP2) 		4 THR A 144
VAL A 439
GLY A 169
THR A 170
 None
 1.10A 3cflA-3hagA:
undetectable		 3cflA-3hagA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hhs PHENOLOXIDASE
SUBUNIT 1

(Manduca sexta) 		PF00372
(Hemocyanin_M)
PF03722
(Hemocyanin_N)
PF03723
(Hemocyanin_C) 		4 THR B 493
VAL B 489
GLY B 499
THR B 500
 None
 1.03A 3cflA-3hhsB:
undetectable		 3cflA-3hhsB:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hkz DNA-DIRECTED RNA
POLYMERASE SUBUNIT B

(Sulfolobus
solfataricus) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 THR B 176
VAL B 322
GLY B 208
THR B 209
 None
 1.06A 3cflA-3hkzB:
undetectable		 3cflA-3hkzB:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3hrv TOXIN COREGULATED
PILIN

(Vibrio cholerae) 		PF05946
(TcpA) 		4 THR A 125
VAL A 194
GLY A 160
THR A 159
 None
 1.09A 3cflA-3hrvA:
undetectable		 3cflA-3hrvA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3jcx FAB E HEAVY CHAIN
FAB E LIGHT CHAIN

(Rattus
norvegicus) 		PF07686
(V-set) 		4 THR L  95
VAL L  27
GLY H 207
THR H 205
 None
 1.09A 3cflA-3jcxL:
undetectable		 3cflA-3jcxL:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3k8z NAD-SPECIFIC
GLUTAMATE
DEHYDROGENASE

(Bacillus
subtilis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 THR A  21
VAL A 410
GLY A 113
THR A  78
 None
 1.06A 3cflA-3k8zA:
undetectable		 3cflA-3k8zA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3l76 ASPARTOKINASE

(Synechocystis
sp. PCC 6803) 		PF00696
(AA_kinase)
PF01842
(ACT)
PF13840
(ACT_7) 		4 THR A 149
VAL A  39
GLY A  10
THR A  11
 None
 0.93A 3cflA-3l76A:
undetectable		 3cflA-3l76A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3lg3 ISOCITRATE LYASE

(Yersinia pestis) 		PF00463
(ICL) 		4 THR A 396
VAL A 404
GLY A  76
THR A  74
 None
 1.03A 3cflA-3lg3A:
undetectable		 3cflA-3lg3A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3num SERINE PROTEASE
HTRA1

(Homo sapiens) 		PF13365
(Trypsin_2) 		4 THR A 293
VAL A 333
GLY A 329
THR A 217
 None
 0.88A 3cflA-3numA:
undetectable		 3cflA-3numA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3nwu SERINE PROTEASE
HTRA1

(Homo sapiens) 		PF13365
(Trypsin_2) 		4 THR A 293
VAL A 333
GLY A 329
THR A 217
 None
 0.90A 3cflA-3nwuA:
undetectable		 3cflA-3nwuA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3p41 GERANYLTRANSTRANSFER
ASE

(Pseudomonas
protegens) 		PF00348
(polyprenyl_synt) 		4 THR A 209
VAL A 189
GLY A 182
THR A 181
 None
 1.04A 3cflA-3p41A:
undetectable		 3cflA-3p41A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ss7 D-SERINE DEHYDRATASE

(Escherichia
coli) 		PF00291
(PALP) 		4 THR X 424
VAL X 429
GLY X 169
THR X 168
 PLP  X 502 (-3.0A)
None
None
None
 1.06A 3cflA-3ss7X:
undetectable		 3cflA-3ss7X:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3uzb BRANCHED-CHAIN-AMINO
-ACID
AMINOTRANSFERASE

(Deinococcus
radiodurans) 		PF01063
(Aminotran_4) 		4 THR A 304
VAL A 341
GLY A 140
THR A 138
 PLP  A 371 ( 3.7A)
None
None
None
 1.04A 3cflA-3uzbA:
undetectable		 3cflA-3uzbA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3vdr D-3-HYDROXYBUTYRATE
DEHYDROGENASE

(Alcaligenes
faecalis) 		PF00106
(adh_short) 		4 THR A 122
VAL A 162
GLY A 248
THR A 249
 None
 1.01A 3cflA-3vdrA:
undetectable		 3cflA-3vdrA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4con ANAEROBIC
RIBONUCLEOSIDE-TRIPH
OSPHATE REDUCTASE

(Thermotoga
maritima) 		PF13597
(NRDD) 		4 THR A 453
VAL A 470
GLY A 442
THR A 441
 None
 0.91A 3cflA-4conA:
undetectable		 3cflA-4conA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fbv MYXOBACTERIAL
HEMAGGLUTININ

(Myxococcus
xanthus) 		no annotation 4 THR A 161
VAL A 170
GLY A 197
THR A 180
 None
None
EDO  A 311 (-3.5A)
None
 1.07A 3cflA-4fbvA:
undetectable		 3cflA-4fbvA:
22.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4fim LACTOTRANSFERRIN

(Bos taurus) 		PF00405
(Transferrin) 		4 THR A 430
VAL A 591
GLY A 662
THR A 663
 None
None
CEL  A 711 (-3.3A)
None
 0.33A 3cflA-4fimA:
31.3		 3cflA-4fimA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4fln PROTEASE DO-LIKE 2,
CHLOROPLASTIC

(Arabidopsis
thaliana) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 THR A 235
VAL A 298
GLY A 269
THR A 156
 None
 1.09A 3cflA-4flnA:
undetectable		 3cflA-4flnA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4h61 MEDIATOR OF RNA
POLYMERASE II
TRANSCRIPTION
SUBUNIT 6

(Schizosaccharomyces
pombe) 		PF04934
(Med6) 		4 THR A 106
VAL A  79
GLY A  75
THR A  74
 None
 0.90A 3cflA-4h61A:
undetectable		 3cflA-4h61A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4hwv PECTATE LYASE/AMB
ALLERGEN

(Acidovorax
citrulli) 		PF00544
(Pec_lyase_C) 		4 THR A 384
VAL A 360
GLY A 321
THR A 298
 None
 1.06A 3cflA-4hwvA:
undetectable		 3cflA-4hwvA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyo CYSTATHIONINE
GAMMA-LYASE-LIKE
PROTEIN, LYS201A
MODIFIED

(Xanthomonas
oryzae) 		PF01053
(Cys_Met_Meta_PP) 		4 THR B  94
VAL B 205
GLY B 220
THR B 209
 None
None
None
LLP  B 210 ( 3.5A)
 1.05A 3cflA-4iyoB:
undetectable		 3cflA-4iyoB:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4iyp IMMUNOGLOBULIN-BINDI
NG PROTEIN 1

(Homo sapiens) 		PF04177
(TAP42) 		4 THR A  89
VAL A  26
GLY A  19
THR A  18
 None
 0.87A 3cflA-4iypA:
undetectable		 3cflA-4iypA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4mla CYTOKININ OXIDASE 2

(Zea mays) 		PF01565
(FAD_binding_4)
PF09265
(Cytokin-bind) 		4 THR A 417
VAL A 187
GLY A 172
THR A 157
 IPA  A 602 (-4.6A)
None
FAD  A 601 (-3.4A)
FAD  A 601 (-4.2A)
 1.05A 3cflA-4mlaA:
undetectable		 3cflA-4mlaA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n0i GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A,
MITOCHONDRIAL
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT B,
MITOCHONDRIAL

(Saccharomyces
cerevisiae) 		PF01425
(Amidase)
PF02934
(GatB_N) 		4 THR A 149
VAL A  80
GLY B  73
THR B  74
 None
 1.04A 3cflA-4n0iA:
2.3		 3cflA-4n0iA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4n6d TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Desulfovibrio
salexigens) 		PF03480
(DctP) 		4 THR A 115
VAL A 274
GLY A 267
THR A 266
 None
 0.90A 3cflA-4n6dA:
undetectable		 3cflA-4n6dA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nap EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 7

(Desulfovibrio
alaskensis) 		PF03480
(DctP) 		4 THR A 118
VAL A 277
GLY A 270
THR A 269
 None
 0.95A 3cflA-4napA:
2.1		 3cflA-4napA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4nq8 PUTATIVE PERIPLASMIC
SUBSTRATE-BINDING
TRANSPORT PROTEIN

(Bordetella
bronchiseptica) 		PF03480
(DctP) 		4 THR A 178
VAL A 232
GLY A 102
THR A 101
 SO4  A 402 (-3.1A)
None
None
None
 0.95A 3cflA-4nq8A:
undetectable		 3cflA-4nq8A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4p7y METHIONINE
GAMMA-LYASE

(Citrobacter
freundii) 		PF01053
(Cys_Met_Meta_PP) 		4 THR A  94
VAL A 205
GLY A 220
THR A 209
 None
None
LLP  A 210 ( 4.8A)
LLP  A 210 ( 3.4A)
 1.04A 3cflA-4p7yA:
undetectable		 3cflA-4p7yA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pdh TRAP DICARBOXYLATE
TRANSPORTER, DCTP
SUBUNIT

(Polaromonas sp.
JS666) 		PF03480
(DctP) 		4 THR A  73
VAL A  61
GLY A 273
THR A 274
 None
 0.98A 3cflA-4pdhA:
2.8		 3cflA-4pdhA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pet EXTRACELLULAR
SOLUTE-BINDING
PROTEIN, FAMILY 7

(Colwellia
psychrerythraea) 		PF03480
(DctP) 		4 THR A 115
VAL A 218
GLY A 238
THR A 237
 None
PYR  A 402 ( 4.6A)
None
None
 1.10A 3cflA-4petA:
1.6		 3cflA-4petA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4pka PATATIN-17

(Solanum
cardiophyllum) 		PF01734
(Patatin) 		4 THR X 148
VAL X 231
GLY X  75
THR X  76
 None
None
None
MIS  X  77 ( 3.8A)
 1.08A 3cflA-4pkaX:
undetectable		 3cflA-4pkaX:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qiw DNA-DIRECTED RNA
POLYMERASE

(Thermococcus
kodakarensis) 		PF00562
(RNA_pol_Rpb2_6)
PF04560
(RNA_pol_Rpb2_7)
PF04561
(RNA_pol_Rpb2_2)
PF04563
(RNA_pol_Rpb2_1)
PF04565
(RNA_pol_Rpb2_3)
PF04566
(RNA_pol_Rpb2_4)
PF04567
(RNA_pol_Rpb2_5) 		4 THR B 443
VAL B 167
GLY B 414
THR B 413
 None
 1.08A 3cflA-4qiwB:
undetectable		 3cflA-4qiwB:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4qzv SPIKE PROTEIN S1

(Tylonycteris
bat coronavirus
HKU4) 		PF09408
(Spike_rec_bind) 		4 THR B  76
VAL B 218
GLY B 212
THR B 213
 None
 1.10A 3cflA-4qzvB:
undetectable		 3cflA-4qzvB:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ri0 SERINE PROTEASE
HTRA3

(Homo sapiens) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 THR A 270
VAL A 310
GLY A 306
THR A 188
 None
 0.88A 3cflA-4ri0A:
undetectable		 3cflA-4ri0A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4trt DNA POLYMERASE III
SUBUNIT BETA

(Deinococcus
radiodurans) 		PF00712
(DNA_pol3_beta)
PF02767
(DNA_pol3_beta_2)
PF02768
(DNA_pol3_beta_3) 		4 THR A 251
VAL A 280
GLY A 306
THR A 307
 None
 0.78A 3cflA-4trtA:
undetectable		 3cflA-4trtA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4u3t PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase) 		4 THR A 539
VAL A 548
GLY A 263
THR A 264
 None
 0.89A 3cflA-4u3tA:
undetectable		 3cflA-4u3tA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4uml GANGLIOSIDE-INDUCED
DIFFERENTIATION-ASSO
CIATED PROTEIN 2

(Homo sapiens) 		PF01661
(Macro) 		4 THR A 188
VAL A 152
GLY A 110
THR A 109
 None
 1.05A 3cflA-4umlA:
undetectable		 3cflA-4umlA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4wj3 ASPARTYL/GLUTAMYL-TR
NA(ASN/GLN)
AMIDOTRANSFERASE
SUBUNIT B
GLUTAMYL-TRNA(GLN)
AMIDOTRANSFERASE
SUBUNIT A

(Pseudomonas
aeruginosa) 		PF01425
(Amidase)
PF02637
(GatB_Yqey)
PF02934
(GatB_N) 		4 THR A 171
VAL A 105
GLY B  46
THR B  47
 None
 1.08A 3cflA-4wj3A:
2.0		 3cflA-4wj3A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4xgi GLUTAMATE
DEHYDROGENASE

(Burkholderia
thailandensis) 		PF00208
(ELFV_dehydrog)
PF02812
(ELFV_dehydrog_N) 		4 THR A 273
VAL A 234
GLY A 209
THR A 208
 None
None
None
NAD  A 500 (-3.3A)
 1.05A 3cflA-4xgiA:
undetectable		 3cflA-4xgiA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ynn PROTEASE DO

(Legionella
pneumophila) 		PF13180
(PDZ_2)
PF13365
(Trypsin_2) 		4 THR A 158
VAL A 195
GLY A 191
THR A  78
 None
 1.07A 3cflA-4ynnA:
undetectable		 3cflA-4ynnA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4yo7 SUGAR ABC
TRANSPORTER
(SUGAR-BINDING
PROTEIN)

(Bacillus
halodurans) 		PF13407
(Peripla_BP_4) 		4 THR A 224
VAL A 229
GLY A 203
THR A 204
 None
 0.55A 3cflA-4yo7A:
2.3		 3cflA-4yo7A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5cm6 TRAP DICARBOXYLATE
TRANSPORTER-DCTP
SUBUNIT

(Pseudoalteromonas
atlantica) 		PF03480
(DctP) 		4 THR A 109
VAL A 212
GLY A 232
THR A 231
 None
PYR  A 401 ( 4.6A)
None
None
 1.07A 3cflA-5cm6A:
1.7		 3cflA-5cm6A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5eio N-ACETYL-GAMMA-GLUTA
MYL-PHOSPHATE/N-ACET
YL-GAMMA-AMINOADIPYL
-PHOSPHATE REDUCTASE

(Thermus
thermophilus) 		PF01118
(Semialdhyde_dh)
PF02774
(Semialdhyde_dhC) 		4 THR A 308
VAL A 285
GLY A 316
THR A 317
 None
None
None
NAP  A 401 (-3.0A)
 1.09A 3cflA-5eioA:
undetectable		 3cflA-5eioA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fuu HIV-1 ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		PF00516
(GP120)
PF00517
(GP41) 		4 THR A  37
VAL A  42
GLY B 531
THR B 529
 None
 1.09A 3cflA-5fuuA:
undetectable		 3cflA-5fuuA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5fyj GP120 ENV ECTODOMAIN
GP41 ENV ECTODOMAIN

(Human
immunodeficiency
virus 1) 		PF00516
(GP120)
PF00517
(GP41) 		4 THR G  37
VAL G  42
GLY B 531
THR B 529
 None
 1.00A 3cflA-5fyjG:
undetectable		 3cflA-5fyjG:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5gxd AMP-DEPENDENT
SYNTHETASE AND
LIGASE

(Dinoroseobacter
shibae) 		PF00501
(AMP-binding)
PF13193
(AMP-binding_C)
PF16177
(ACAS_N) 		4 THR A 507
VAL A 528
GLY A 592
THR A 593
 None
 0.94A 3cflA-5gxdA:
undetectable		 3cflA-5gxdA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5i67 PHOSPHOENOLPYRUVATE
CARBOXYKINASE [GTP]

(Mycobacterium
tuberculosis) 		PF00821
(PEPCK_C)
PF17297
(PEPCK_N) 		4 THR A 442
VAL A 424
GLY A 540
THR A 541
 None
 0.60A 3cflA-5i67A:
undetectable		 3cflA-5i67A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE

(Flavobacterium
psychrophilum) 		PF10459
(Peptidase_S46) 		4 THR A 570
VAL A 649
GLY A 645
THR A  80
 None
 0.89A 3cflA-5jxfA:
undetectable		 3cflA-5jxfA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ksh PENICILLIN-BINDING
PROTEIN 2

(Neisseria
gonorrhoeae) 		PF00905
(Transpeptidase)
PF03717
(PBP_dimer) 		4 THR A 539
VAL A 548
GLY A 263
THR A 264
 None
 0.87A 3cflA-5kshA:
undetectable		 3cflA-5kshA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ltm PHENYLALANINE
AMMONIA LYASE

(Anabaena) 		no annotation 4 THR B 156
VAL B  41
GLY B 230
THR B 229
 None
 0.91A 3cflA-5ltmB:
undetectable		 3cflA-5ltmB:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5n8m RISC-LOADING COMPLEX
SUBUNIT TARBP2

(Homo sapiens) 		no annotation 4 THR A  71
VAL A  47
GLY A  39
THR A  40
 None
None
None
C  B  19 ( 2.9A)
 1.05A 3cflA-5n8mA:
undetectable		 3cflA-5n8mA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5oup PERFORIN-LIKE
PROTEIN 1

(Toxoplasma
gondii) 		no annotation 4 THR A 609
VAL A 616
GLY A 662
THR A 663
 None
 1.04A 3cflA-5oupA:
undetectable		 3cflA-5oupA:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5szs SPIKE GLYCOPROTEIN

(Human
coronavirus
NL63) 		PF01600
(Corona_S1)
PF01601
(Corona_S2) 		4 THR A 653
VAL A 474
GLY A 637
THR A 638
 None
NAG  A1442 ( 4.3A)
None
None
 1.09A 3cflA-5szsA:
undetectable		 3cflA-5szsA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u0s MEDIATOR COMPLEX
SUBUNIT 6

(Schizosaccharomyces
pombe) 		PF04934
(Med6) 		4 THR F 106
VAL F  79
GLY F  75
THR F  74
 None
 0.87A 3cflA-5u0sF:
undetectable		 3cflA-5u0sF:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5u65 VHH-5

(Camelus
dromedarius) 		PF07686
(V-set) 		4 THR A  28
VAL A  78
GLY A  55
THR A  56
 SO4  A 202 (-3.4A)
None
None
None
 0.66A 3cflA-5u65A:
undetectable		 3cflA-5u65A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5um8 GLYCOPROTEIN GP120
GLYCOPROTEIN GP41

(Human
immunodeficiency
virus 1) 		PF00516
(GP120)
PF00517
(GP41) 		4 THR G  37
VAL G  42
GLY B 531
THR B 529
 None
 1.10A 3cflA-5um8G:
undetectable		 3cflA-5um8G:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5yu1 LYSINE
CYCLODEAMINASE

(Streptomyces
pristinaespiralis) 		no annotation 4 THR A 118
VAL A 233
GLY A 147
THR A 146
 YCP  A 403 (-4.0A)
NAD  A 402 (-4.2A)
NAD  A 402 (-3.3A)
None
 1.04A 3cflA-5yu1A:
undetectable		 3cflA-5yu1A:
13.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6b0n ENVELOPE
GLYCOPROTEIN GP140

(Human
immunodeficiency
virus 1) 		no annotation 4 THR G  37
VAL G  42
GLY G 531
THR G 529
 None
 1.04A 3cflA-6b0nG:
undetectable		 3cflA-6b0nG:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ca7 PCT64_13C HEAVY
CHAIN

(Homo sapiens) 		no annotation 4 THR H  28
VAL H  78
GLY H  55
THR H  56
 None
 0.79A 3cflA-6ca7H:
undetectable		 3cflA-6ca7H:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ccb GLYCOPROTEIN 120
GLYCOPROTEIN 41

(Human
immunodeficiency
virus 1) 		no annotation 4 THR C  37
VAL C  42
GLY A 531
THR A 529
 None
 1.04A 3cflA-6ccbC:
undetectable		 3cflA-6ccbC:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6cfw MONOVALENT CATION/H+
ANTIPORTER SUBUNIT E
MONOVALENT CATION/H+
ANTIPORTER SUBUNIT G

(Pyrococcus
furiosus) 		no annotation 4 THR C  33
VAL A  83
GLY A  90
THR A  89
 None
 1.09A 3cflA-6cfwC:
undetectable		 3cflA-6cfwC:
12.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ck9 GP120 OF ENVELOPE
GLYCOPROTEIN GP160
GP41 ECTODOMAIN OF
ENVELOPE
GLYCOPROTEIN GP160

(Human
immunodeficiency
virus 1) 		no annotation 4 THR G  37
VAL G  42
GLY B 531
THR B 529
 None
 1.05A 3cflA-6ck9G:
undetectable		 3cflA-6ck9G:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6fq3 E3 UBIQUITIN-PROTEIN
LIGASE TRIM71

(Danio rerio) 		no annotation 4 THR A 806
VAL A 577
GLY A 593
THR A 594
 None
 0.98A 3cflA-6fq3A:
undetectable		 3cflA-6fq3A:
13.04